Browse entries in the PDBbind-CN Database
HEADER RNA BINDING PROTEIN/RNA 01-JAN-17 5WWG TITLE CRYSTAL STRUCTURE OF HNRNPA2B1 IN COMPLEX WITH AAGGACUUGC COMPND MOL_ID: 1; COMPND 2 MOLECULE: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: RRMS (UNP RESIDUES 12-195); COMPND 5 SYNONYM: HNRNP A2/B1; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3'); COMPND 9 CHAIN: B; COMPND 10 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: HNRNPA2B1, HNRPA2B1; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 MOL_ID: 2; SOURCE 9 SYNTHETIC: YES; SOURCE 10 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 11 ORGANISM_TAXID: 32630 KEYWDS HNRNP, RRM, RNA BINDING PROTEIN-RNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR B.X.WU,S.C.SU,J.B.MA REVDAT 3 14-FEB-18 5WWG 1 JRNL REVDAT 2 07-FEB-18 5WWG 1 JRNL REVDAT 1 17-JAN-18 5WWG 0 JRNL AUTH B.WU,S.SU,D.P.PATIL,H.LIU,J.GAN,S.R.JAFFREY,J.MA JRNL TITL MOLECULAR BASIS FOR THE SPECIFIC AND MULTIVARIANT JRNL TITL 2 RECOGNITIONS OF RNA SUBSTRATES BY HUMAN HNRNP A2/B1. JRNL REF NAT COMMUN V. 9 420 2018 JRNL REFN ESSN 2041-1723 JRNL PMID 29379020 JRNL DOI 10.1038/S41467-017-02770-Z REMARK 2 REMARK 2 RESOLUTION. 2.03 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.8.0135 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.03 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 30.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 COMPLETENESS FOR RANGE (%) : 97.1 REMARK 3 NUMBER OF REFLECTIONS : 12210 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.201 REMARK 3 R VALUE (WORKING SET) : 0.199 REMARK 3 FREE R VALUE : 0.256 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.800 REMARK 3 FREE R VALUE TEST SET COUNT : 616 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.03 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.08 REMARK 3 REFLECTION IN BIN (WORKING SET) : 874 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 94.72 REMARK 3 BIN R VALUE (WORKING SET) : 0.2640 REMARK 3 BIN FREE R VALUE SET COUNT : 41 REMARK 3 BIN FREE R VALUE : 0.3070 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 1491 REMARK 3 NUCLEIC ACID ATOMS : 169 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 33 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 42.80 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : -0.09000 REMARK 3 B22 (A**2) : 2.35000 REMARK 3 B33 (A**2) : -1.67000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : -1.01000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.237 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.201 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.163 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 6.235 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.960 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.934 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1754 ; 0.016 ; 0.018 REMARK 3 BOND LENGTHS OTHERS (A): 1579 ; 0.002 ; 0.020 REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 2390 ; 1.831 ; 1.859 REMARK 3 BOND ANGLES OTHERS (DEGREES): 3649 ; 1.115 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 192 ; 6.895 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 81 ;32.666 ;22.840 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 297 ;17.665 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 17 ;17.684 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 248 ; 0.111 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 1868 ; 0.008 ; 0.020 REMARK 3 GENERAL PLANES OTHERS (A): 421 ; 0.002 ; 0.020 REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 760 ; 3.499 ; 3.882 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): 759 ; 3.485 ; 3.880 REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 953 ; 4.781 ; 5.799 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): 954 ; 4.780 ; 5.802 REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 994 ; 4.388 ; 4.505 REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): 993 ; 4.389 ; 4.503 REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): 1437 ; 6.590 ; 6.569 REMARK 3 LONG RANGE B REFINED ATOMS (A**2): 2008 ; 8.125 ;32.306 REMARK 3 LONG RANGE B OTHER ATOMS (A**2): 2005 ; 8.127 ;32.285 REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.20 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS REMARK 4 REMARK 4 5WWG COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 06-JAN-17. REMARK 100 THE DEPOSITION ID IS D_1300002508. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 13-OCT-16 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 9.0 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : SSRF REMARK 200 BEAMLINE : BL18U1 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.97776 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS3 S 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO REMARK 200 DATA SCALING SOFTWARE : HKL-3000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 14087 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.030 REMARK 200 RESOLUTION RANGE LOW (A) : 50.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 95.9 REMARK 200 DATA REDUNDANCY : 4.900 REMARK 200 R MERGE (I) : NULL REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 2.4000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.03 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.08 REMARK 200 COMPLETENESS FOR SHELL (%) : NULL REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : NULL REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: 5EN1 REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 42.35 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.13 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 25% (W/V) PEG 1500, 0.1M MMT/SODIUM REMARK 280 HYDROXIDE PH 9.0, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y,-Z REMARK 290 3555 X+1/2,Y+1/2,Z REMARK 290 4555 -X+1/2,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 3 1.000000 0.000000 0.000000 66.40500 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 23.11400 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 66.40500 REMARK 290 SMTRY2 4 0.000000 1.000000 0.000000 23.11400 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 1420 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 11880 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -1.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 G B 9 REMARK 465 C B 10 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS REMARK 500 REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC REMARK 500 SYMMETRY ARE IN CLOSE CONTACT. AN ATOM LOCATED WITHIN 0.15 REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375 REMARK 500 INSTEAD OF REMARK 500. ATOMS WITH NON-BLANK ALTERNATE REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS. REMARK 500 REMARK 500 DISTANCE CUTOFF: REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI SSYMOP DISTANCE REMARK 500 NH1 ARG A 89 O TYR A 174 1556 2.14 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 ASP A 76 CB - CG - OD1 ANGL. DEV. = 7.3 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 LYS A 120 -155.78 57.08 REMARK 500 LYS A 173 -56.14 75.02 REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 5WWE RELATED DB: PDB REMARK 900 RELATED ID: 5WWF RELATED DB: PDB REMARK 900 RELATED ID: 5WWH RELATED DB: PDB DBREF 5WWG A 12 195 UNP P22626 ROA2_HUMAN 12 195 DBREF 5WWG B 1 10 PDB 5WWG 5WWG 1 10 SEQRES 1 A 184 ARG LYS LYS ARG GLU LYS GLU GLN PHE ARG LYS LEU PHE SEQRES 2 A 184 ILE GLY GLY LEU SER PHE GLU THR THR GLU GLU SER LEU SEQRES 3 A 184 ARG ASN TYR TYR GLU GLN TRP GLY LYS LEU THR ASP CYS SEQRES 4 A 184 VAL VAL MET ARG ASP PRO ALA SER LYS ARG SER ARG GLY SEQRES 5 A 184 PHE GLY PHE VAL THR PHE SER SER MET ALA GLU VAL ASP SEQRES 6 A 184 ALA ALA MET ALA ALA ARG PRO HIS SER ILE ASP GLY ARG SEQRES 7 A 184 VAL VAL GLU PRO LYS ARG ALA VAL ALA ARG GLU GLU SER SEQRES 8 A 184 GLY LYS PRO GLY ALA HIS VAL THR VAL LYS LYS LEU PHE SEQRES 9 A 184 VAL GLY GLY ILE LYS GLU ASP THR GLU GLU HIS HIS LEU SEQRES 10 A 184 ARG ASP TYR PHE GLU GLU TYR GLY LYS ILE ASP THR ILE SEQRES 11 A 184 GLU ILE ILE THR ASP ARG GLN SER GLY LYS LYS ARG GLY SEQRES 12 A 184 PHE GLY PHE VAL THR PHE ASP ASP HIS ASP PRO VAL ASP SEQRES 13 A 184 LYS ILE VAL LEU GLN LYS TYR HIS THR ILE ASN GLY HIS SEQRES 14 A 184 ASN ALA GLU VAL ARG LYS ALA LEU SER ARG GLN GLU MET SEQRES 15 A 184 GLN GLU SEQRES 1 B 10 A A G G A C U U G C FORMUL 3 HOH *33(H2 O) HELIX 1 AA1 ARG A 12 PHE A 20 1 9 HELIX 2 AA2 THR A 33 GLU A 42 1 10 HELIX 3 AA3 GLN A 43 GLY A 45 5 3 HELIX 4 AA4 SER A 71 ALA A 81 1 11 HELIX 5 AA5 ALA A 98 SER A 102 5 5 HELIX 6 AA6 GLU A 124 GLU A 133 1 10 HELIX 7 AA7 GLU A 134 GLY A 136 5 3 HELIX 8 AA8 ASP A 162 LYS A 173 1 12 HELIX 9 AA9 SER A 189 GLN A 194 1 6 SHEET 1 AA1 4 LEU A 47 ARG A 54 0 SHEET 2 AA1 4 SER A 61 PHE A 69 -1 O PHE A 66 N VAL A 51 SHEET 3 AA1 4 LYS A 22 GLY A 26 -1 N ILE A 25 O GLY A 65 SHEET 4 AA1 4 GLU A 92 ARG A 95 -1 O LYS A 94 N PHE A 24 SHEET 1 AA2 2 SER A 85 ILE A 86 0 SHEET 2 AA2 2 ARG A 89 VAL A 90 -1 O ARG A 89 N ILE A 86 SHEET 1 AA3 5 ILE A 138 THR A 145 0 SHEET 2 AA3 5 LYS A 152 PHE A 160 -1 O THR A 159 N ASP A 139 SHEET 3 AA3 5 LYS A 113 GLY A 117 -1 N LEU A 114 O VAL A 158 SHEET 4 AA3 5 HIS A 180 LYS A 186 -1 O ARG A 185 N PHE A 115 SHEET 5 AA3 5 HIS A 175 ILE A 177 -1 N ILE A 177 O HIS A 180 CISPEP 1 ARG A 82 PRO A 83 0 2.55 CRYST1 132.810 46.228 33.994 90.00 102.22 90.00 C 1 2 1 4 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.007530 0.000000 0.001631 0.00000 SCALE2 0.000000 0.021632 0.000000 0.00000 SCALE3 0.000000 0.000000 0.030099 0.00000 ATOM 1 N ARG A 12 37.755 14.311 9.021 1.00 66.59 N ATOM 2 CA ARG A 12 37.171 15.643 8.832 1.00 61.11 C ATOM 3 C ARG A 12 35.842 15.508 8.067 1.00 61.29 C ATOM 4 O ARG A 12 34.795 15.953 8.528 1.00 59.13 O ATOM 5 CB ARG A 12 38.119 16.551 8.010 1.00 66.73 C ATOM 6 CG ARG A 12 39.444 16.981 8.646 1.00 71.87 C ATOM 7 CD ARG A 12 39.283 17.837 9.909 1.00 74.48 C ATOM 8 NE ARG A 12 39.080 19.275 9.678 1.00 75.68 N ATOM 9 CZ ARG A 12 37.900 19.900 9.526 1.00 73.59 C ATOM 10 NH1 ARG A 12 37.886 21.221 9.352 1.00 72.10 N ATOM 11 NH2 ARG A 12 36.737 19.239 9.530 1.00 66.61 N ATOM 12 N LYS A 13 35.909 14.861 6.905 1.00 60.02 N ATOM 13 CA LYS A 13 34.774 14.682 5.992 1.00 61.81 C ATOM 14 C LYS A 13 33.535 14.067 6.659 1.00 61.57 C ATOM 15 O LYS A 13 32.428 14.555 6.453 1.00 57.93 O ATOM 16 CB LYS A 13 35.231 13.798 4.826 1.00 70.04 C ATOM 17 CG LYS A 13 34.323 13.748 3.605 1.00 79.35 C ATOM 18 CD LYS A 13 34.947 12.896 2.488 1.00 86.89 C ATOM 19 CE LYS A 13 36.389 13.301 2.145 1.00 92.25 C ATOM 20 NZ LYS A 13 36.851 12.858 0.800 1.00 97.83 N ATOM 21 N LYS A 14 33.718 13.002 7.452 1.00 63.87 N ATOM 22 CA LYS A 14 32.602 12.411 8.245 1.00 65.72 C ATOM 23 C LYS A 14 31.952 13.456 9.173 1.00 56.81 C ATOM 24 O LYS A 14 30.717 13.642 9.210 1.00 46.64 O ATOM 25 CB LYS A 14 33.066 11.207 9.105 1.00 74.16 C ATOM 26 CG LYS A 14 33.009 9.848 8.413 1.00 81.43 C ATOM 27 CD LYS A 14 32.885 8.674 9.390 1.00 83.14 C ATOM 28 CE LYS A 14 34.115 8.488 10.273 1.00 90.26 C ATOM 29 NZ LYS A 14 33.952 9.074 11.637 1.00 95.41 N ATOM 30 N ARG A 15 32.808 14.111 9.935 1.00 51.81 N ATOM 31 CA ARG A 15 32.406 15.162 10.867 1.00 52.39 C ATOM 32 C ARG A 15 31.502 16.232 10.230 1.00 50.14 C ATOM 33 O ARG A 15 30.495 16.731 10.798 1.00 45.47 O ATOM 34 CB ARG A 15 33.672 15.815 11.395 1.00 53.33 C ATOM 35 CG ARG A 15 33.474 16.454 12.720 1.00 63.51 C ATOM 36 CD ARG A 15 33.455 15.417 13.835 1.00 65.87 C ATOM 37 NE ARG A 15 33.299 16.207 15.038 1.00 68.95 N ATOM 38 CZ ARG A 15 34.288 16.700 15.779 1.00 75.29 C ATOM 39 NH1 ARG A 15 33.966 17.467 16.814 1.00 87.56 N ATOM 40 NH2 ARG A 15 35.576 16.432 15.527 1.00 74.83 N ATOM 41 N GLU A 16 31.851 16.582 9.015 1.00 47.62 N ATOM 42 CA GLU A 16 31.043 17.526 8.309 1.00 47.13 C ATOM 43 C GLU A 16 29.698 16.955 8.079 1.00 44.22 C ATOM 44 O GLU A 16 28.718 17.657 8.265 1.00 46.11 O ATOM 45 CB GLU A 16 31.677 17.927 6.985 1.00 58.97 C ATOM 46 CG GLU A 16 33.120 18.403 7.104 1.00 65.94 C ATOM 47 CD GLU A 16 33.384 19.251 8.342 1.00 76.85 C ATOM 48 OE1 GLU A 16 34.079 18.754 9.261 1.00100.35 O ATOM 49 OE2 GLU A 16 32.885 20.399 8.402 1.00 82.09 O ATOM 50 N LYS A 17 29.636 15.686 7.682 1.00 45.10 N ATOM 51 CA LYS A 17 28.336 14.994 7.430 1.00 46.12 C ATOM 52 C LYS A 17 27.451 14.910 8.646 1.00 45.55 C ATOM 53 O LYS A 17 26.236 15.168 8.592 1.00 41.96 O ATOM 54 CB LYS A 17 28.526 13.540 6.899 1.00 46.86 C ATOM 55 CG LYS A 17 28.439 13.377 5.383 1.00 54.21 C ATOM 56 CD LYS A 17 29.067 12.072 4.846 1.00 56.39 C ATOM 57 CE LYS A 17 29.320 12.179 3.348 1.00 64.72 C ATOM 58 NZ LYS A 17 30.759 12.011 2.994 1.00 66.96 N ATOM 59 N GLU A 18 28.050 14.464 9.736 1.00 44.88 N ATOM 60 CA GLU A 18 27.298 14.244 10.930 1.00 47.78 C ATOM 61 C GLU A 18 26.810 15.559 11.538 1.00 44.53 C ATOM 62 O GLU A 18 25.774 15.581 12.227 1.00 42.24 O ATOM 63 CB GLU A 18 28.093 13.361 11.906 1.00 58.28 C ATOM 64 CG GLU A 18 29.317 14.026 12.516 1.00 64.97 C ATOM 65 CD GLU A 18 30.049 13.152 13.546 1.00 66.07 C ATOM 66 OE1 GLU A 18 30.506 12.039 13.150 1.00 60.23 O ATOM 67 OE2 GLU A 18 30.171 13.612 14.734 1.00 58.57 O ATOM 68 N GLN A 19 27.447 16.688 11.206 1.00 40.41 N ATOM 69 CA GLN A 19 26.940 17.924 11.736 1.00 35.38 C ATOM 70 C GLN A 19 25.511 18.073 11.338 1.00 42.89 C ATOM 71 O GLN A 19 24.739 18.592 12.124 1.00 48.79 O ATOM 72 CB GLN A 19 27.720 19.145 11.287 1.00 40.93 C ATOM 73 CG GLN A 19 27.271 20.436 11.970 1.00 43.34 C ATOM 74 CD GLN A 19 27.374 20.362 13.508 1.00 43.44 C ATOM 75 OE1 GLN A 19 28.419 19.910 14.034 1.00 42.25 O ATOM 76 NE2 GLN A 19 26.291 20.781 14.238 1.00 33.35 N ATOM 77 N PHE A 20 25.132 17.571 10.155 1.00 34.27 N ATOM 78 CA PHE A 20 23.763 17.692 9.649 1.00 33.28 C ATOM 79 C PHE A 20 22.810 16.608 10.112 1.00 30.98 C ATOM 80 O PHE A 20 21.685 16.519 9.658 1.00 32.51 O ATOM 81 CB PHE A 20 23.808 17.740 8.115 1.00 39.23 C ATOM 82 CG PHE A 20 24.613 18.908 7.583 1.00 42.29 C ATOM 83 CD1 PHE A 20 24.055 20.193 7.495 1.00 44.69 C ATOM 84 CD2 PHE A 20 25.954 18.749 7.243 1.00 45.51 C ATOM 85 CE1 PHE A 20 24.812 21.276 7.035 1.00 46.42 C ATOM 86 CE2 PHE A 20 26.725 19.838 6.762 1.00 48.90 C ATOM 87 CZ PHE A 20 26.149 21.102 6.677 1.00 48.49 C ATOM 88 N ARG A 21 23.280 15.791 11.037 1.00 30.16 N ATOM 89 CA ARG A 21 22.533 14.720 11.618 1.00 30.56 C ATOM 90 C ARG A 21 22.405 14.883 13.125 1.00 28.78 C ATOM 91 O ARG A 21 22.089 13.927 13.825 1.00 27.01 O ATOM 92 CB ARG A 21 23.315 13.427 11.343 1.00 32.96 C ATOM 93 CG ARG A 21 23.433 13.090 9.849 1.00 34.34 C ATOM 94 CD ARG A 21 24.403 11.937 9.619 1.00 37.87 C ATOM 95 NE ARG A 21 24.667 11.732 8.191 1.00 37.70 N ATOM 96 CZ ARG A 21 25.322 10.690 7.702 1.00 43.61 C ATOM 97 NH1 ARG A 21 25.776 9.739 8.522 1.00 44.39 N ATOM 98 NH2 ARG A 21 25.512 10.575 6.393 1.00 40.88 N ATOM 99 N LYS A 22 22.606 16.087 13.616 1.00 27.84 N ATOM 100 CA LYS A 22 22.757 16.303 15.020 1.00 27.76 C ATOM 101 C LYS A 22 21.596 17.147 15.493 1.00 27.36 C ATOM 102 O LYS A 22 21.227 18.097 14.829 1.00 26.06 O ATOM 103 CB LYS A 22 24.052 17.046 15.220 1.00 30.22 C ATOM 104 CG LYS A 22 24.567 17.157 16.613 1.00 35.93 C ATOM 105 CD LYS A 22 26.081 17.347 16.507 1.00 39.76 C ATOM 106 CE LYS A 22 26.712 17.088 17.826 1.00 47.40 C ATOM 107 NZ LYS A 22 28.117 17.510 17.761 1.00 47.05 N ATOM 108 N LEU A 23 21.023 16.779 16.634 1.00 24.92 N ATOM 109 CA LEU A 23 20.051 17.585 17.315 1.00 24.72 C ATOM 110 C LEU A 23 20.623 18.165 18.614 1.00 24.70 C ATOM 111 O LEU A 23 21.235 17.442 19.376 1.00 24.30 O ATOM 112 CB LEU A 23 18.844 16.737 17.661 1.00 26.03 C ATOM 113 CG LEU A 23 17.982 16.277 16.530 1.00 29.07 C ATOM 114 CD1 LEU A 23 16.760 15.614 17.149 1.00 27.94 C ATOM 115 CD2 LEU A 23 17.634 17.441 15.581 1.00 29.04 C ATOM 116 N PHE A 24 20.468 19.482 18.786 1.00 24.31 N ATOM 117 CA PHE A 24 20.420 20.159 20.069 1.00 23.41 C ATOM 118 C PHE A 24 19.158 19.777 20.828 1.00 24.66 C ATOM 119 O PHE A 24 18.049 19.905 20.287 1.00 25.81 O ATOM 120 CB PHE A 24 20.407 21.665 19.822 1.00 27.10 C ATOM 121 CG PHE A 24 20.358 22.500 21.080 1.00 24.51 C ATOM 122 CD1 PHE A 24 21.516 22.916 21.666 1.00 25.16 C ATOM 123 CD2 PHE A 24 19.156 22.881 21.619 1.00 27.43 C ATOM 124 CE1 PHE A 24 21.474 23.773 22.764 1.00 29.65 C ATOM 125 CE2 PHE A 24 19.102 23.663 22.775 1.00 29.24 C ATOM 126 CZ PHE A 24 20.256 24.113 23.340 1.00 26.48 C ATOM 127 N ILE A 25 19.314 19.287 22.058 1.00 23.60 N ATOM 128 CA ILE A 25 18.175 18.984 22.927 1.00 25.85 C ATOM 129 C ILE A 25 18.227 19.850 24.165 1.00 26.58 C ATOM 130 O ILE A 25 19.055 19.613 25.053 1.00 27.10 O ATOM 131 CB ILE A 25 18.104 17.493 23.377 1.00 24.39 C ATOM 132 CG1 ILE A 25 18.371 16.518 22.210 1.00 25.66 C ATOM 133 CG2 ILE A 25 16.765 17.213 24.014 1.00 27.02 C ATOM 134 CD1 ILE A 25 17.342 16.536 21.083 1.00 28.07 C ATOM 135 N GLY A 26 17.363 20.860 24.226 1.00 29.91 N ATOM 136 CA GLY A 26 17.353 21.777 25.367 1.00 28.66 C ATOM 137 C GLY A 26 16.167 21.504 26.259 1.00 26.87 C ATOM 138 O GLY A 26 15.369 20.591 25.985 1.00 28.03 O ATOM 139 N GLY A 27 16.093 22.209 27.373 1.00 27.53 N ATOM 140 CA GLY A 27 14.999 21.962 28.321 1.00 28.28 C ATOM 141 C GLY A 27 15.110 20.619 29.059 1.00 29.18 C ATOM 142 O GLY A 27 14.094 20.030 29.439 1.00 32.05 O ATOM 143 N LEU A 28 16.334 20.122 29.241 1.00 31.47 N ATOM 144 CA LEU A 28 16.543 18.798 29.877 1.00 33.12 C ATOM 145 C LEU A 28 16.260 18.818 31.361 1.00 29.50 C ATOM 146 O LEU A 28 16.725 19.702 32.063 1.00 26.34 O ATOM 147 CB LEU A 28 17.988 18.295 29.754 1.00 32.60 C ATOM 148 CG LEU A 28 18.448 17.928 28.329 1.00 29.33 C ATOM 149 CD1 LEU A 28 19.854 17.366 28.374 1.00 30.29 C ATOM 150 CD2 LEU A 28 17.513 17.003 27.630 1.00 30.52 C ATOM 151 N SER A 29 15.520 17.819 31.839 1.00 32.63 N ATOM 152 CA SER A 29 15.510 17.542 33.277 1.00 31.97 C ATOM 153 C SER A 29 16.969 17.449 33.709 1.00 32.14 C ATOM 154 O SER A 29 17.872 16.922 32.978 1.00 29.52 O ATOM 155 CB SER A 29 14.712 16.288 33.648 1.00 33.03 C ATOM 156 OG SER A 29 15.059 15.897 34.952 1.00 36.45 O ATOM 157 N PHE A 30 17.227 17.966 34.888 1.00 31.71 N ATOM 158 CA PHE A 30 18.535 17.778 35.529 1.00 36.64 C ATOM 159 C PHE A 30 18.763 16.340 35.908 1.00 35.93 C ATOM 160 O PHE A 30 19.879 15.973 36.226 1.00 37.00 O ATOM 161 CB PHE A 30 18.690 18.698 36.772 1.00 39.88 C ATOM 162 CG PHE A 30 18.753 20.163 36.406 1.00 44.42 C ATOM 163 CD1 PHE A 30 19.828 20.654 35.690 1.00 48.28 C ATOM 164 CD2 PHE A 30 17.714 21.036 36.720 1.00 42.97 C ATOM 165 CE1 PHE A 30 19.874 21.991 35.313 1.00 57.21 C ATOM 166 CE2 PHE A 30 17.773 22.365 36.376 1.00 46.83 C ATOM 167 CZ PHE A 30 18.838 22.852 35.655 1.00 50.03 C ATOM 168 N GLU A 31 17.737 15.506 35.866 1.00 35.71 N ATOM 169 CA GLU A 31 17.999 14.077 35.970 1.00 40.96 C ATOM 170 C GLU A 31 18.469 13.358 34.692 1.00 36.75 C ATOM 171 O GLU A 31 18.873 12.237 34.742 1.00 29.94 O ATOM 172 CB GLU A 31 16.792 13.350 36.506 1.00 44.19 C ATOM 173 CG GLU A 31 16.734 13.343 38.025 1.00 46.44 C ATOM 174 CD GLU A 31 15.521 12.570 38.508 1.00 46.94 C ATOM 175 OE1 GLU A 31 14.470 12.614 37.815 1.00 45.13 O ATOM 176 OE2 GLU A 31 15.619 11.900 39.564 1.00 43.03 O ATOM 177 N THR A 32 18.438 14.006 33.555 1.00 32.71 N ATOM 178 CA THR A 32 18.589 13.297 32.312 1.00 29.87 C ATOM 179 C THR A 32 20.073 12.999 32.139 1.00 31.48 C ATOM 180 O THR A 32 20.877 13.793 32.443 1.00 35.33 O ATOM 181 CB THR A 32 17.940 14.102 31.149 1.00 30.07 C ATOM 182 OG1 THR A 32 16.495 14.009 31.265 1.00 29.79 O ATOM 183 CG2 THR A 32 18.355 13.571 29.808 1.00 32.04 C ATOM 184 N THR A 33 20.392 11.792 31.721 1.00 32.62 N ATOM 185 CA THR A 33 21.732 11.393 31.415 1.00 35.91 C ATOM 186 C THR A 33 21.877 11.068 29.930 1.00 30.44 C ATOM 187 O THR A 33 20.899 11.042 29.179 1.00 29.90 O ATOM 188 CB THR A 33 22.043 10.099 32.185 1.00 36.79 C ATOM 189 OG1 THR A 33 21.101 9.112 31.766 1.00 32.19 O ATOM 190 CG2 THR A 33 21.935 10.314 33.693 1.00 40.41 C ATOM 191 N GLU A 34 23.111 10.820 29.523 1.00 30.03 N ATOM 192 CA GLU A 34 23.410 10.278 28.198 1.00 31.90 C ATOM 193 C GLU A 34 22.618 9.032 27.929 1.00 32.37 C ATOM 194 O GLU A 34 22.037 8.867 26.864 1.00 27.59 O ATOM 195 CB GLU A 34 24.870 9.888 28.026 1.00 34.75 C ATOM 196 CG GLU A 34 25.813 11.037 27.761 1.00 38.61 C ATOM 197 CD GLU A 34 26.152 11.871 28.999 1.00 38.58 C ATOM 198 OE1 GLU A 34 26.849 12.946 28.881 1.00 29.45 O ATOM 199 OE2 GLU A 34 25.680 11.475 30.090 1.00 42.69 O ATOM 200 N GLU A 35 22.602 8.129 28.907 1.00 33.46 N ATOM 201 CA GLU A 35 21.821 6.887 28.733 1.00 33.13 C ATOM 202 C GLU A 35 20.324 7.106 28.527 1.00 30.86 C ATOM 203 O GLU A 35 19.745 6.436 27.675 1.00 29.97 O ATOM 204 CB GLU A 35 22.063 5.791 29.821 1.00 37.54 C ATOM 205 CG GLU A 35 22.666 6.202 31.148 1.00 45.65 C ATOM 206 CD GLU A 35 24.090 6.593 30.989 1.00 43.22 C ATOM 207 OE1 GLU A 35 24.782 5.944 30.172 1.00 47.93 O ATOM 208 OE2 GLU A 35 24.483 7.582 31.616 1.00 49.92 O ATOM 209 N SER A 36 19.683 8.004 29.277 1.00 28.99 N ATOM 210 CA SER A 36 18.225 8.222 29.135 1.00 33.37 C ATOM 211 C SER A 36 17.937 9.039 27.882 1.00 33.25 C ATOM 212 O SER A 36 16.904 8.906 27.229 1.00 33.34 O ATOM 213 CB SER A 36 17.623 8.903 30.397 1.00 37.95 C ATOM 214 OG SER A 36 18.170 10.214 30.697 1.00 33.08 O ATOM 215 N LEU A 37 18.894 9.871 27.511 1.00 31.76 N ATOM 216 CA LEU A 37 18.755 10.612 26.283 1.00 30.96 C ATOM 217 C LEU A 37 18.842 9.625 25.098 1.00 32.65 C ATOM 218 O LEU A 37 18.025 9.626 24.156 1.00 28.02 O ATOM 219 CB LEU A 37 19.862 11.671 26.246 1.00 36.23 C ATOM 220 CG LEU A 37 19.684 12.848 25.291 1.00 39.82 C ATOM 221 CD1 LEU A 37 18.311 13.508 25.500 1.00 37.37 C ATOM 222 CD2 LEU A 37 20.834 13.838 25.457 1.00 35.69 C ATOM 223 N ARG A 38 19.842 8.753 25.161 1.00 32.53 N ATOM 224 CA ARG A 38 20.078 7.775 24.082 1.00 34.08 C ATOM 225 C ARG A 38 18.913 6.797 23.936 1.00 34.11 C ATOM 226 O ARG A 38 18.481 6.500 22.840 1.00 31.38 O ATOM 227 CB ARG A 38 21.416 7.079 24.361 1.00 38.47 C ATOM 228 CG ARG A 38 21.911 6.095 23.334 1.00 43.27 C ATOM 229 CD ARG A 38 23.291 5.550 23.768 1.00 45.32 C ATOM 230 NE ARG A 38 24.417 6.506 23.734 1.00 47.68 N ATOM 231 CZ ARG A 38 25.168 6.795 22.649 1.00 48.92 C ATOM 232 NH1 ARG A 38 24.930 6.247 21.454 1.00 44.19 N ATOM 233 NH2 ARG A 38 26.174 7.663 22.749 1.00 45.67 N ATOM 234 N ASN A 39 18.380 6.303 25.052 1.00 36.57 N ATOM 235 CA ASN A 39 17.175 5.444 25.033 1.00 35.57 C ATOM 236 C ASN A 39 16.015 6.070 24.365 1.00 32.09 C ATOM 237 O ASN A 39 15.324 5.427 23.641 1.00 37.15 O ATOM 238 CB ASN A 39 16.699 5.126 26.415 1.00 40.44 C ATOM 239 CG ASN A 39 17.399 3.972 26.954 1.00 51.33 C ATOM 240 OD1 ASN A 39 17.203 2.862 26.458 1.00 67.81 O ATOM 241 ND2 ASN A 39 18.296 4.200 27.902 1.00 53.94 N ATOM 242 N TYR A 40 15.784 7.341 24.639 1.00 35.12 N ATOM 243 CA TYR A 40 14.645 8.013 24.052 1.00 30.08 C ATOM 244 C TYR A 40 14.872 8.180 22.549 1.00 28.78 C ATOM 245 O TYR A 40 14.011 7.854 21.768 1.00 31.74 O ATOM 246 CB TYR A 40 14.336 9.334 24.754 1.00 32.67 C ATOM 247 CG TYR A 40 13.063 9.994 24.183 1.00 33.36 C ATOM 248 CD1 TYR A 40 11.777 9.673 24.696 1.00 34.97 C ATOM 249 CD2 TYR A 40 13.145 10.880 23.156 1.00 29.84 C ATOM 250 CE1 TYR A 40 10.624 10.221 24.161 1.00 35.02 C ATOM 251 CE2 TYR A 40 12.008 11.406 22.605 1.00 35.78 C ATOM 252 CZ TYR A 40 10.748 11.088 23.149 1.00 33.28 C ATOM 253 OH TYR A 40 9.668 11.655 22.603 1.00 34.53 O ATOM 254 N TYR A 41 16.029 8.657 22.126 1.00 30.34 N ATOM 255 CA TYR A 41 16.163 9.010 20.706 1.00 29.33 C ATOM 256 C TYR A 41 16.446 7.809 19.839 1.00 31.66 C ATOM 257 O TYR A 41 16.243 7.880 18.632 1.00 31.26 O ATOM 258 CB TYR A 41 17.140 10.174 20.469 1.00 30.09 C ATOM 259 CG TYR A 41 16.452 11.472 20.770 1.00 31.66 C ATOM 260 CD1 TYR A 41 15.500 11.988 19.900 1.00 31.30 C ATOM 261 CD2 TYR A 41 16.703 12.156 21.949 1.00 32.98 C ATOM 262 CE1 TYR A 41 14.847 13.165 20.186 1.00 32.15 C ATOM 263 CE2 TYR A 41 16.014 13.326 22.267 1.00 32.76 C ATOM 264 CZ TYR A 41 15.117 13.834 21.376 1.00 31.63 C ATOM 265 OH TYR A 41 14.470 14.982 21.714 1.00 32.76 O ATOM 266 N GLU A 42 16.857 6.687 20.430 1.00 35.40 N ATOM 267 CA GLU A 42 17.086 5.469 19.637 1.00 36.82 C ATOM 268 C GLU A 42 15.826 4.952 18.982 1.00 37.99 C ATOM 269 O GLU A 42 15.924 4.238 17.997 1.00 37.01 O ATOM 270 CB GLU A 42 17.766 4.389 20.449 1.00 39.57 C ATOM 271 CG GLU A 42 19.259 4.610 20.426 1.00 46.38 C ATOM 272 CD GLU A 42 20.053 3.689 21.303 1.00 55.27 C ATOM 273 OE1 GLU A 42 21.319 3.751 21.208 1.00 67.27 O ATOM 274 OE2 GLU A 42 19.419 2.935 22.081 1.00 58.04 O ATOM 275 N GLN A 43 14.646 5.336 19.474 1.00 37.58 N ATOM 276 CA GLN A 43 13.438 4.946 18.766 1.00 41.03 C ATOM 277 C GLN A 43 13.323 5.476 17.363 1.00 44.99 C ATOM 278 O GLN A 43 12.451 4.996 16.643 1.00 46.30 O ATOM 279 CB GLN A 43 12.161 5.260 19.572 1.00 46.07 C ATOM 280 CG GLN A 43 11.873 6.724 19.837 1.00 49.33 C ATOM 281 CD GLN A 43 10.919 6.953 21.041 1.00 52.06 C ATOM 282 OE1 GLN A 43 11.291 7.507 22.093 1.00 42.93 O ATOM 283 NE2 GLN A 43 9.655 6.546 20.857 1.00 52.07 N ATOM 284 N TRP A 44 14.140 6.461 16.953 1.00 37.31 N ATOM 285 CA TRP A 44 14.103 6.926 15.560 1.00 37.56 C ATOM 286 C TRP A 44 15.362 6.666 14.765 1.00 37.82 C ATOM 287 O TRP A 44 15.425 7.002 13.572 1.00 46.43 O ATOM 288 CB TRP A 44 13.798 8.410 15.483 1.00 35.57 C ATOM 289 CG TRP A 44 12.508 8.690 16.043 1.00 38.97 C ATOM 290 CD1 TRP A 44 11.277 8.429 15.477 1.00 37.56 C ATOM 291 CD2 TRP A 44 12.263 9.246 17.308 1.00 39.83 C ATOM 292 NE1 TRP A 44 10.299 8.790 16.341 1.00 39.76 N ATOM 293 CE2 TRP A 44 10.874 9.336 17.458 1.00 40.66 C ATOM 294 CE3 TRP A 44 13.089 9.704 18.334 1.00 40.67 C ATOM 295 CZ2 TRP A 44 10.283 9.852 18.610 1.00 40.94 C ATOM 296 CZ3 TRP A 44 12.505 10.235 19.458 1.00 41.88 C ATOM 297 CH2 TRP A 44 11.107 10.297 19.592 1.00 39.76 C ATOM 298 N GLY A 45 16.365 6.118 15.408 1.00 40.17 N ATOM 299 CA GLY A 45 17.588 5.762 14.693 1.00 40.97 C ATOM 300 C GLY A 45 18.717 5.248 15.543 1.00 39.93 C ATOM 301 O GLY A 45 18.559 4.981 16.735 1.00 42.45 O ATOM 302 N LYS A 46 19.870 5.159 14.892 1.00 42.99 N ATOM 303 CA LYS A 46 21.099 4.702 15.501 1.00 43.71 C ATOM 304 C LYS A 46 21.924 5.923 15.835 1.00 38.27 C ATOM 305 O LYS A 46 22.263 6.707 14.956 1.00 40.01 O ATOM 306 CB LYS A 46 21.879 3.840 14.527 1.00 49.20 C ATOM 307 CG LYS A 46 21.079 2.674 13.950 1.00 59.26 C ATOM 308 CD LYS A 46 21.538 2.381 12.535 1.00 61.42 C ATOM 309 CE LYS A 46 20.831 1.158 12.002 1.00 65.16 C ATOM 310 NZ LYS A 46 21.671 0.528 10.961 1.00 68.65 N ATOM 311 N LEU A 47 22.257 6.069 17.098 1.00 30.65 N ATOM 312 CA LEU A 47 23.001 7.206 17.507 1.00 33.64 C ATOM 313 C LEU A 47 24.491 6.908 17.433 1.00 32.45 C ATOM 314 O LEU A 47 24.932 5.837 17.826 1.00 37.18 O ATOM 315 CB LEU A 47 22.639 7.614 18.890 1.00 30.39 C ATOM 316 CG LEU A 47 21.142 7.714 19.186 1.00 33.60 C ATOM 317 CD1 LEU A 47 21.031 8.502 20.466 1.00 34.05 C ATOM 318 CD2 LEU A 47 20.322 8.391 18.126 1.00 34.47 C ATOM 319 N THR A 48 25.269 7.846 16.915 1.00 30.36 N ATOM 320 CA THR A 48 26.744 7.708 16.933 1.00 27.06 C ATOM 321 C THR A 48 27.377 8.554 18.012 1.00 27.10 C ATOM 322 O THR A 48 28.580 8.484 18.227 1.00 26.24 O ATOM 323 CB THR A 48 27.352 8.062 15.571 1.00 28.22 C ATOM 324 OG1 THR A 48 27.111 9.423 15.331 1.00 28.62 O ATOM 325 CG2 THR A 48 26.701 7.307 14.432 1.00 31.50 C ATOM 326 N ASP A 49 26.572 9.374 18.707 1.00 28.49 N ATOM 327 CA ASP A 49 27.061 10.265 19.770 1.00 28.82 C ATOM 328 C ASP A 49 25.876 10.775 20.586 1.00 30.77 C ATOM 329 O ASP A 49 24.747 10.903 20.099 1.00 29.56 O ATOM 330 CB ASP A 49 27.786 11.485 19.179 1.00 27.50 C ATOM 331 CG ASP A 49 28.616 12.252 20.213 1.00 31.94 C ATOM 332 OD1 ASP A 49 28.964 11.647 21.259 1.00 33.62 O ATOM 333 OD2 ASP A 49 28.902 13.482 20.018 1.00 29.77 O ATOM 334 N CYS A 50 26.145 11.073 21.830 1.00 31.16 N ATOM 335 CA CYS A 50 25.135 11.561 22.730 1.00 32.99 C ATOM 336 C CYS A 50 25.849 12.220 23.916 1.00 37.01 C ATOM 337 O CYS A 50 26.741 11.608 24.505 1.00 40.96 O ATOM 338 CB CYS A 50 24.219 10.445 23.191 1.00 31.79 C ATOM 339 SG CYS A 50 23.022 11.156 24.361 1.00 39.87 S ATOM 340 N VAL A 51 25.506 13.461 24.258 1.00 32.89 N ATOM 341 CA VAL A 51 26.239 14.127 25.333 1.00 34.24 C ATOM 342 C VAL A 51 25.305 15.054 26.052 1.00 32.14 C ATOM 343 O VAL A 51 24.463 15.631 25.408 1.00 34.09 O ATOM 344 CB VAL A 51 27.490 14.849 24.789 1.00 38.05 C ATOM 345 CG1 VAL A 51 27.144 15.876 23.685 1.00 36.24 C ATOM 346 CG2 VAL A 51 28.296 15.481 25.906 1.00 38.82 C ATOM 347 N VAL A 52 25.396 15.090 27.384 1.00 29.22 N ATOM 348 CA VAL A 52 24.764 16.076 28.228 1.00 30.02 C ATOM 349 C VAL A 52 25.864 17.040 28.666 1.00 33.46 C ATOM 350 O VAL A 52 26.829 16.643 29.318 1.00 36.63 O ATOM 351 CB VAL A 52 24.110 15.529 29.495 1.00 30.25 C ATOM 352 CG1 VAL A 52 23.546 16.700 30.327 1.00 30.98 C ATOM 353 CG2 VAL A 52 23.004 14.543 29.176 1.00 29.95 C ATOM 354 N AMET A 53 25.708 18.309 28.304 0.50 31.51 N ATOM 355 N BMET A 53 25.720 18.306 28.269 0.50 33.06 N ATOM 356 CA AMET A 53 26.722 19.301 28.533 0.50 32.54 C ATOM 357 CA BMET A 53 26.708 19.328 28.527 0.50 34.93 C ATOM 358 C AMET A 53 26.599 19.725 29.993 0.50 32.60 C ATOM 359 C BMET A 53 26.599 19.695 29.999 0.50 33.99 C ATOM 360 O AMET A 53 25.492 19.864 30.516 0.50 29.66 O ATOM 361 O BMET A 53 25.493 19.791 30.539 0.50 30.44 O ATOM 362 CB AMET A 53 26.547 20.444 27.527 0.50 31.19 C ATOM 363 CB BMET A 53 26.465 20.539 27.613 0.50 35.09 C ATOM 364 CG AMET A 53 27.037 20.042 26.144 0.50 31.54 C ATOM 365 CG BMET A 53 27.427 20.612 26.440 0.50 36.88 C ATOM 366 SD AMET A 53 28.832 19.701 26.076 0.50 28.36 S ATOM 367 SD BMET A 53 27.321 19.141 25.396 0.50 36.91 S ATOM 368 CE AMET A 53 29.252 19.382 27.778 0.50 32.51 C ATOM 369 CE BMET A 53 28.966 19.080 24.697 0.50 32.07 C ATOM 370 N ARG A 54 27.733 19.807 30.673 1.00 36.20 N ATOM 371 CA AARG A 54 27.760 20.036 32.124 0.50 37.12 C ATOM 372 CA BARG A 54 27.704 20.064 32.110 0.50 37.75 C ATOM 373 C ARG A 54 28.728 21.143 32.463 1.00 37.56 C ATOM 374 O ARG A 54 29.685 21.396 31.702 1.00 38.98 O ATOM 375 CB AARG A 54 28.237 18.791 32.881 0.50 36.32 C ATOM 376 CB BARG A 54 27.955 18.775 32.940 0.50 37.24 C ATOM 377 CG AARG A 54 27.211 17.703 33.043 0.50 35.72 C ATOM 378 CG BARG A 54 26.979 17.615 32.704 0.50 38.79 C ATOM 379 CD AARG A 54 27.880 16.364 33.271 0.50 35.11 C ATOM 380 CD BARG A 54 27.250 16.416 33.614 0.50 37.80 C ATOM 381 NE AARG A 54 26.893 15.309 33.253 0.50 34.05 N ATOM 382 NE BARG A 54 26.227 15.359 33.575 0.50 40.97 N ATOM 383 CZ AARG A 54 26.686 14.469 32.243 0.50 32.57 C ATOM 384 CZ BARG A 54 25.143 15.313 34.348 0.50 39.57 C ATOM 385 NH1AARG A 54 27.441 14.535 31.138 0.50 29.13 N ATOM 386 NH1BARG A 54 24.907 16.276 35.223 0.50 39.72 N ATOM 387 NH2AARG A 54 25.726 13.549 32.367 0.50 30.42 N ATOM 388 NH2BARG A 54 24.303 14.295 34.251 0.50 40.66 N ATOM 389 N ASP A 55 28.507 21.791 33.617 1.00 39.62 N ATOM 390 CA ASP A 55 29.492 22.772 34.100 1.00 47.00 C ATOM 391 C ASP A 55 30.803 22.022 34.323 1.00 44.95 C ATOM 392 O ASP A 55 30.760 20.972 34.994 1.00 43.02 O ATOM 393 CB ASP A 55 29.070 23.450 35.437 1.00 51.18 C ATOM 394 CG ASP A 55 30.076 24.508 35.894 1.00 54.42 C ATOM 395 OD1 ASP A 55 30.259 25.491 35.146 1.00 69.46 O ATOM 396 OD2 ASP A 55 30.711 24.355 36.966 1.00 58.66 O ATOM 397 N PRO A 56 31.948 22.541 33.771 1.00 43.49 N ATOM 398 CA PRO A 56 33.261 21.941 34.045 1.00 48.67 C ATOM 399 C PRO A 56 33.510 21.737 35.537 1.00 52.67 C ATOM 400 O PRO A 56 33.790 20.599 35.935 1.00 51.52 O ATOM 401 CB PRO A 56 34.245 22.931 33.425 1.00 48.47 C ATOM 402 CG PRO A 56 33.489 23.461 32.255 1.00 47.23 C ATOM 403 CD PRO A 56 32.057 23.580 32.734 1.00 44.21 C ATOM 404 N ALA A 57 33.332 22.781 36.355 1.00 45.43 N ATOM 405 CA ALA A 57 33.626 22.664 37.759 1.00 41.73 C ATOM 406 C ALA A 57 32.620 21.767 38.457 1.00 46.35 C ATOM 407 O ALA A 57 32.983 20.770 39.040 1.00 53.85 O ATOM 408 CB ALA A 57 33.618 24.019 38.401 1.00 41.27 C ATOM 409 N SER A 58 31.353 22.133 38.409 1.00 47.11 N ATOM 410 CA SER A 58 30.355 21.481 39.243 1.00 49.96 C ATOM 411 C SER A 58 29.845 20.147 38.686 1.00 49.68 C ATOM 412 O SER A 58 29.372 19.329 39.483 1.00 39.07 O ATOM 413 CB SER A 58 29.174 22.424 39.540 1.00 54.34 C ATOM 414 OG SER A 58 28.374 22.718 38.396 1.00 56.10 O ATOM 415 N LYS A 59 29.891 19.950 37.344 1.00 46.74 N ATOM 416 CA LYS A 59 29.320 18.763 36.689 1.00 44.53 C ATOM 417 C LYS A 59 27.816 18.846 36.708 1.00 47.85 C ATOM 418 O LYS A 59 27.157 17.839 36.394 1.00 43.51 O ATOM 419 CB LYS A 59 29.697 17.414 37.385 1.00 47.18 C ATOM 420 CG LYS A 59 31.189 17.122 37.487 1.00 50.64 C ATOM 421 CD LYS A 59 31.752 16.800 36.118 1.00 54.14 C ATOM 422 CE LYS A 59 32.200 18.027 35.352 1.00 53.09 C ATOM 423 NZ LYS A 59 33.691 18.015 35.166 1.00 55.48 N ATOM 424 N ARG A 60 27.271 20.006 37.110 1.00 44.36 N ATOM 425 CA ARG A 60 25.837 20.234 37.082 1.00 51.49 C ATOM 426 C ARG A 60 25.471 20.334 35.586 1.00 40.13 C ATOM 427 O ARG A 60 26.197 20.934 34.798 1.00 36.38 O ATOM 428 CB ARG A 60 25.450 21.505 37.886 1.00 58.34 C ATOM 429 CG ARG A 60 24.003 21.527 38.385 1.00 67.05 C ATOM 430 CD ARG A 60 23.770 22.719 39.305 1.00 67.57 C ATOM 431 NE ARG A 60 22.364 23.138 39.300 1.00 75.36 N ATOM 432 CZ ARG A 60 21.733 23.784 38.302 1.00 76.85 C ATOM 433 NH1 ARG A 60 22.362 24.096 37.170 1.00 77.20 N ATOM 434 NH2 ARG A 60 20.441 24.117 38.425 1.00 68.08 N ATOM 435 N SER A 61 24.368 19.705 35.236 1.00 41.17 N ATOM 436 CA SER A 61 23.837 19.722 33.853 1.00 38.96 C ATOM 437 C SER A 61 23.580 21.187 33.494 1.00 40.51 C ATOM 438 O SER A 61 23.102 21.976 34.331 1.00 34.04 O ATOM 439 CB SER A 61 22.579 18.840 33.800 1.00 37.32 C ATOM 440 OG SER A 61 21.817 18.988 32.616 1.00 38.97 O ATOM 441 N ARG A 62 23.968 21.574 32.279 1.00 37.60 N ATOM 442 CA ARG A 62 23.621 22.891 31.748 1.00 35.24 C ATOM 443 C ARG A 62 22.225 22.885 31.127 1.00 32.43 C ATOM 444 O ARG A 62 21.831 23.829 30.489 1.00 30.40 O ATOM 445 CB ARG A 62 24.683 23.360 30.756 1.00 35.88 C ATOM 446 CG ARG A 62 26.034 23.559 31.440 1.00 36.26 C ATOM 447 CD ARG A 62 27.139 23.878 30.473 1.00 38.04 C ATOM 448 NE ARG A 62 26.757 25.028 29.675 1.00 38.10 N ATOM 449 CZ ARG A 62 27.354 25.394 28.557 1.00 37.35 C ATOM 450 NH1 ARG A 62 28.340 24.685 28.036 1.00 42.73 N ATOM 451 NH2 ARG A 62 26.943 26.467 27.926 1.00 40.41 N ATOM 452 N GLY A 63 21.488 21.805 31.317 1.00 27.64 N ATOM 453 CA GLY A 63 20.128 21.716 30.865 1.00 29.96 C ATOM 454 C GLY A 63 19.970 21.485 29.385 1.00 26.59 C ATOM 455 O GLY A 63 18.852 21.568 28.895 1.00 26.91 O ATOM 456 N PHE A 64 21.053 21.114 28.702 1.00 28.10 N ATOM 457 CA PHE A 64 20.976 20.753 27.270 1.00 27.71 C ATOM 458 C PHE A 64 22.015 19.722 26.849 1.00 26.03 C ATOM 459 O PHE A 64 23.032 19.504 27.530 1.00 29.06 O ATOM 460 CB PHE A 64 21.120 22.043 26.359 1.00 27.89 C ATOM 461 CG PHE A 64 22.534 22.528 26.238 1.00 28.56 C ATOM 462 CD1 PHE A 64 23.059 23.346 27.219 1.00 31.61 C ATOM 463 CD2 PHE A 64 23.352 22.143 25.172 1.00 27.45 C ATOM 464 CE1 PHE A 64 24.374 23.759 27.168 1.00 28.39 C ATOM 465 CE2 PHE A 64 24.675 22.543 25.105 1.00 27.64 C ATOM 466 CZ PHE A 64 25.177 23.380 26.080 1.00 28.87 C ATOM 467 N GLY A 65 21.766 19.110 25.695 1.00 22.12 N ATOM 468 CA GLY A 65 22.712 18.217 25.119 1.00 26.76 C ATOM 469 C GLY A 65 22.575 18.066 23.626 1.00 23.71 C ATOM 470 O GLY A 65 21.809 18.768 22.991 1.00 24.53 O ATOM 471 N PHE A 66 23.323 17.111 23.104 1.00 26.34 N ATOM 472 CA PHE A 66 23.284 16.760 21.684 1.00 24.97 C ATOM 473 C PHE A 66 23.170 15.256 21.539 1.00 25.43 C ATOM 474 O PHE A 66 23.763 14.488 22.300 1.00 25.59 O ATOM 475 CB PHE A 66 24.566 17.258 20.936 1.00 26.88 C ATOM 476 CG PHE A 66 24.758 18.762 20.932 1.00 26.68 C ATOM 477 CD1 PHE A 66 24.164 19.537 19.975 1.00 26.28 C ATOM 478 CD2 PHE A 66 25.560 19.416 21.907 1.00 28.85 C ATOM 479 CE1 PHE A 66 24.291 20.905 19.969 1.00 26.60 C ATOM 480 CE2 PHE A 66 25.700 20.793 21.884 1.00 29.30 C ATOM 481 CZ PHE A 66 25.058 21.539 20.886 1.00 27.02 C ATOM 482 N VAL A 67 22.445 14.853 20.515 1.00 27.41 N ATOM 483 CA VAL A 67 22.455 13.510 19.980 1.00 31.60 C ATOM 484 C VAL A 67 22.747 13.621 18.480 1.00 29.02 C ATOM 485 O VAL A 67 22.210 14.514 17.784 1.00 27.59 O ATOM 486 CB VAL A 67 21.108 12.758 20.219 1.00 33.85 C ATOM 487 CG1 VAL A 67 20.724 12.699 21.704 1.00 34.38 C ATOM 488 CG2 VAL A 67 19.987 13.383 19.464 1.00 35.67 C ATOM 489 N THR A 68 23.540 12.673 17.989 1.00 27.55 N ATOM 490 CA THR A 68 23.918 12.567 16.568 1.00 26.28 C ATOM 491 C THR A 68 23.413 11.218 16.025 1.00 27.23 C ATOM 492 O THR A 68 23.665 10.179 16.611 1.00 26.35 O ATOM 493 CB THR A 68 25.456 12.576 16.451 1.00 26.73 C ATOM 494 OG1 THR A 68 25.946 13.720 17.110 1.00 26.95 O ATOM 495 CG2 THR A 68 25.913 12.595 15.036 1.00 27.46 C ATOM 496 N PHE A 69 22.629 11.273 14.966 1.00 28.01 N ATOM 497 CA PHE A 69 21.986 10.102 14.345 1.00 30.60 C ATOM 498 C PHE A 69 22.867 9.629 13.158 1.00 30.20 C ATOM 499 O PHE A 69 23.820 10.266 12.827 1.00 27.09 O ATOM 500 CB PHE A 69 20.610 10.496 13.770 1.00 27.85 C ATOM 501 CG PHE A 69 19.585 10.802 14.795 1.00 30.22 C ATOM 502 CD1 PHE A 69 19.476 12.097 15.326 1.00 34.98 C ATOM 503 CD2 PHE A 69 18.751 9.807 15.262 1.00 30.29 C ATOM 504 CE1 PHE A 69 18.548 12.386 16.303 1.00 34.95 C ATOM 505 CE2 PHE A 69 17.807 10.094 16.236 1.00 33.01 C ATOM 506 CZ PHE A 69 17.694 11.372 16.736 1.00 33.51 C ATOM 507 N SER A 70 22.470 8.561 12.483 1.00 34.19 N ATOM 508 CA SER A 70 23.252 8.001 11.382 1.00 37.32 C ATOM 509 C SER A 70 22.917 8.612 10.041 1.00 41.99 C ATOM 510 O SER A 70 23.750 8.566 9.174 1.00 44.80 O ATOM 511 CB SER A 70 23.075 6.503 11.383 1.00 37.71 C ATOM 512 OG SER A 70 23.619 6.051 12.618 1.00 40.29 O ATOM 513 N SER A 71 21.743 9.238 9.918 1.00 40.30 N ATOM 514 CA SER A 71 21.300 9.910 8.710 1.00 41.26 C ATOM 515 C SER A 71 20.386 11.094 9.000 1.00 41.21 C ATOM 516 O SER A 71 19.717 11.135 10.067 1.00 33.61 O ATOM 517 CB SER A 71 20.486 8.921 7.874 1.00 43.71 C ATOM 518 OG SER A 71 19.125 8.981 8.249 1.00 45.76 O ATOM 519 N MET A 72 20.275 11.990 8.012 1.00 40.10 N ATOM 520 CA MET A 72 19.355 13.142 8.099 1.00 42.33 C ATOM 521 C MET A 72 17.891 12.706 8.079 1.00 40.36 C ATOM 522 O MET A 72 17.046 13.373 8.654 1.00 33.32 O ATOM 523 CB MET A 72 19.572 14.159 6.980 1.00 44.99 C ATOM 524 CG MET A 72 20.903 14.908 7.038 1.00 51.60 C ATOM 525 SD MET A 72 21.069 16.246 5.788 1.00 68.90 S ATOM 526 CE MET A 72 22.819 16.329 5.414 1.00 71.37 C ATOM 527 N ALA A 73 17.612 11.555 7.481 1.00 40.02 N ATOM 528 CA ALA A 73 16.286 10.968 7.561 1.00 44.12 C ATOM 529 C ALA A 73 15.856 10.619 8.979 1.00 39.53 C ATOM 530 O ALA A 73 14.663 10.688 9.299 1.00 39.47 O ATOM 531 CB ALA A 73 16.183 9.718 6.689 1.00 47.18 C ATOM 532 N GLU A 74 16.785 10.196 9.817 1.00 35.71 N ATOM 533 CA GLU A 74 16.419 9.741 11.176 1.00 37.03 C ATOM 534 C GLU A 74 16.139 10.974 12.058 1.00 36.15 C ATOM 535 O GLU A 74 15.270 10.966 12.911 1.00 40.37 O ATOM 536 CB GLU A 74 17.507 8.865 11.791 1.00 37.06 C ATOM 537 CG GLU A 74 17.811 7.513 11.125 1.00 39.25 C ATOM 538 CD GLU A 74 19.083 6.888 11.692 1.00 40.35 C ATOM 539 OE1 GLU A 74 19.940 7.634 12.140 1.00 43.26 O ATOM 540 OE2 GLU A 74 19.243 5.667 11.739 1.00 43.89 O ATOM 541 N VAL A 75 16.857 12.039 11.766 1.00 34.87 N ATOM 542 CA VAL A 75 16.587 13.320 12.337 1.00 31.43 C ATOM 543 C VAL A 75 15.202 13.753 11.956 1.00 34.88 C ATOM 544 O VAL A 75 14.462 14.252 12.800 1.00 30.50 O ATOM 545 CB VAL A 75 17.596 14.374 11.887 1.00 35.74 C ATOM 546 CG1 VAL A 75 17.243 15.778 12.446 1.00 38.32 C ATOM 547 CG2 VAL A 75 19.011 13.962 12.318 1.00 37.63 C ATOM 548 N ASP A 76 14.848 13.600 10.682 1.00 39.22 N ATOM 549 CA ASP A 76 13.555 14.098 10.218 1.00 39.21 C ATOM 550 C ASP A 76 12.438 13.311 10.909 1.00 34.68 C ATOM 551 O ASP A 76 11.449 13.878 11.309 1.00 37.96 O ATOM 552 CB ASP A 76 13.430 14.007 8.715 1.00 37.09 C ATOM 553 CG ASP A 76 14.244 15.060 7.957 1.00 40.22 C ATOM 554 OD1 ASP A 76 14.610 16.174 8.415 1.00 41.61 O ATOM 555 OD2 ASP A 76 14.514 14.782 6.813 1.00 36.70 O ATOM 556 N ALA A 77 12.653 12.019 11.082 1.00 35.46 N ATOM 557 CA ALA A 77 11.685 11.157 11.738 1.00 35.73 C ATOM 558 C ALA A 77 11.549 11.563 13.207 1.00 38.09 C ATOM 559 O ALA A 77 10.441 11.640 13.709 1.00 40.91 O ATOM 560 CB ALA A 77 12.102 9.714 11.630 1.00 32.09 C ATOM 561 N ALA A 78 12.659 11.837 13.896 1.00 33.88 N ATOM 562 CA ALA A 78 12.570 12.348 15.263 1.00 31.64 C ATOM 563 C ALA A 78 11.804 13.670 15.309 1.00 29.42 C ATOM 564 O ALA A 78 10.864 13.802 16.083 1.00 32.75 O ATOM 565 CB ALA A 78 13.957 12.465 15.939 1.00 31.80 C ATOM 566 N MET A 79 12.143 14.635 14.459 1.00 29.06 N ATOM 567 CA MET A 79 11.450 15.935 14.499 1.00 28.21 C ATOM 568 C MET A 79 9.987 15.837 14.096 1.00 33.03 C ATOM 569 O MET A 79 9.199 16.561 14.637 1.00 33.48 O ATOM 570 CB MET A 79 12.150 16.993 13.673 1.00 28.76 C ATOM 571 CG MET A 79 13.578 17.249 14.154 1.00 31.81 C ATOM 572 SD MET A 79 13.549 17.955 15.821 1.00 31.56 S ATOM 573 CE MET A 79 12.986 19.635 15.603 1.00 29.09 C ATOM 574 N ALA A 80 9.636 14.950 13.159 1.00 37.66 N ATOM 575 CA ALA A 80 8.213 14.675 12.820 1.00 36.49 C ATOM 576 C ALA A 80 7.412 14.109 14.031 1.00 39.13 C ATOM 577 O ALA A 80 6.171 14.214 14.074 1.00 37.85 O ATOM 578 CB ALA A 80 8.134 13.709 11.631 1.00 36.11 C ATOM 579 N ALA A 81 8.100 13.557 15.026 1.00 35.52 N ATOM 580 CA ALA A 81 7.416 13.004 16.192 1.00 37.65 C ATOM 581 C ALA A 81 7.435 13.877 17.451 1.00 37.75 C ATOM 582 O ALA A 81 7.261 13.360 18.541 1.00 39.21 O ATOM 583 CB ALA A 81 7.958 11.618 16.484 1.00 37.34 C ATOM 584 N ARG A 82 7.647 15.199 17.312 1.00 35.54 N ATOM 585 CA ARG A 82 7.480 16.076 18.429 1.00 31.49 C ATOM 586 C ARG A 82 6.006 16.047 18.847 1.00 38.84 C ATOM 587 O ARG A 82 5.198 15.772 17.999 1.00 37.06 O ATOM 588 CB ARG A 82 7.903 17.472 18.066 1.00 31.91 C ATOM 589 CG ARG A 82 9.443 17.578 18.081 1.00 34.65 C ATOM 590 CD ARG A 82 9.927 18.850 17.451 1.00 32.69 C ATOM 591 NE ARG A 82 9.494 18.884 16.070 1.00 35.28 N ATOM 592 CZ ARG A 82 9.251 19.991 15.366 1.00 35.45 C ATOM 593 NH1 ARG A 82 9.348 21.191 15.909 1.00 33.67 N ATOM 594 NH2 ARG A 82 8.854 19.879 14.103 1.00 35.25 N ATOM 595 N PRO A 83 5.645 16.344 20.095 1.00 34.35 N ATOM 596 CA PRO A 83 6.548 16.769 21.166 1.00 34.31 C ATOM 597 C PRO A 83 7.252 15.585 21.780 1.00 35.96 C ATOM 598 O PRO A 83 6.758 14.468 21.675 1.00 33.70 O ATOM 599 CB PRO A 83 5.588 17.406 22.199 1.00 39.34 C ATOM 600 CG PRO A 83 4.266 16.734 21.973 1.00 38.77 C ATOM 601 CD PRO A 83 4.223 16.396 20.496 1.00 36.60 C ATOM 602 N HIS A 84 8.439 15.815 22.334 1.00 33.02 N ATOM 603 CA HIS A 84 9.233 14.792 22.961 1.00 32.91 C ATOM 604 C HIS A 84 9.279 14.998 24.447 1.00 33.02 C ATOM 605 O HIS A 84 9.538 16.078 24.921 1.00 34.27 O ATOM 606 CB HIS A 84 10.671 14.832 22.463 1.00 31.09 C ATOM 607 CG HIS A 84 10.806 14.554 21.008 1.00 31.67 C ATOM 608 ND1 HIS A 84 11.945 14.860 20.282 1.00 30.71 N ATOM 609 CD2 HIS A 84 9.948 13.988 20.136 1.00 29.34 C ATOM 610 CE1 HIS A 84 11.764 14.516 19.025 1.00 27.79 C ATOM 611 NE2 HIS A 84 10.581 13.936 18.921 1.00 32.53 N ATOM 612 N SER A 85 8.999 13.968 25.206 1.00 35.77 N ATOM 613 CA SER A 85 9.183 14.090 26.642 1.00 37.89 C ATOM 614 C SER A 85 10.061 12.973 27.116 1.00 31.49 C ATOM 615 O SER A 85 9.956 11.828 26.716 1.00 34.51 O ATOM 616 CB SER A 85 7.859 14.244 27.428 1.00 42.03 C ATOM 617 OG SER A 85 6.975 13.237 27.073 1.00 43.63 O ATOM 618 N ILE A 86 10.991 13.364 27.941 1.00 30.18 N ATOM 619 CA ILE A 86 12.092 12.573 28.380 1.00 29.69 C ATOM 620 C ILE A 86 12.208 12.902 29.842 1.00 29.50 C ATOM 621 O ILE A 86 12.155 14.101 30.233 1.00 28.14 O ATOM 622 CB ILE A 86 13.392 13.011 27.654 1.00 33.59 C ATOM 623 CG1 ILE A 86 13.185 12.992 26.127 1.00 34.08 C ATOM 624 CG2 ILE A 86 14.579 12.184 28.107 1.00 30.13 C ATOM 625 CD1 ILE A 86 14.421 13.300 25.299 1.00 36.40 C ATOM 626 N ASP A 87 12.338 11.861 30.651 1.00 30.57 N ATOM 627 CA ASP A 87 12.484 11.958 32.080 1.00 32.37 C ATOM 628 C ASP A 87 11.453 12.894 32.708 1.00 34.20 C ATOM 629 O ASP A 87 11.789 13.625 33.619 1.00 35.86 O ATOM 630 CB ASP A 87 13.940 12.377 32.426 1.00 34.71 C ATOM 631 CG ASP A 87 14.975 11.278 32.106 1.00 37.67 C ATOM 632 OD1 ASP A 87 14.650 10.074 32.214 1.00 47.15 O ATOM 633 OD2 ASP A 87 16.135 11.586 31.769 1.00 38.19 O ATOM 634 N GLY A 88 10.216 12.885 32.187 1.00 35.63 N ATOM 635 CA GLY A 88 9.117 13.646 32.731 1.00 39.99 C ATOM 636 C GLY A 88 9.082 15.127 32.369 1.00 46.59 C ATOM 637 O GLY A 88 8.423 15.900 33.043 1.00 41.95 O ATOM 638 N ARG A 89 9.773 15.522 31.308 1.00 42.25 N ATOM 639 CA ARG A 89 9.707 16.882 30.800 1.00 44.22 C ATOM 640 C ARG A 89 9.526 16.869 29.301 1.00 46.96 C ATOM 641 O ARG A 89 10.196 16.102 28.601 1.00 43.62 O ATOM 642 CB ARG A 89 11.028 17.577 31.071 1.00 46.42 C ATOM 643 CG ARG A 89 11.009 18.546 32.209 1.00 50.87 C ATOM 644 CD ARG A 89 12.389 19.104 32.370 1.00 55.29 C ATOM 645 NE ARG A 89 12.405 20.533 32.609 1.00 62.63 N ATOM 646 CZ ARG A 89 12.246 21.460 31.683 1.00 61.92 C ATOM 647 NH1 ARG A 89 12.335 22.718 32.045 1.00 64.29 N ATOM 648 NH2 ARG A 89 12.000 21.145 30.406 1.00 68.20 N ATOM 649 N VAL A 90 8.713 17.776 28.788 1.00 41.18 N ATOM 650 CA VAL A 90 8.750 18.035 27.369 1.00 40.28 C ATOM 651 C VAL A 90 10.061 18.798 27.067 1.00 39.91 C ATOM 652 O VAL A 90 10.390 19.749 27.733 1.00 42.57 O ATOM 653 CB VAL A 90 7.569 18.849 26.932 1.00 42.23 C ATOM 654 CG1 VAL A 90 7.598 18.999 25.402 1.00 43.93 C ATOM 655 CG2 VAL A 90 6.299 18.162 27.413 1.00 46.32 C ATOM 656 N VAL A 91 10.834 18.340 26.105 1.00 35.73 N ATOM 657 CA VAL A 91 12.160 18.922 25.888 1.00 34.18 C ATOM 658 C VAL A 91 12.011 19.702 24.618 1.00 35.45 C ATOM 659 O VAL A 91 10.919 19.699 23.992 1.00 32.32 O ATOM 660 CB VAL A 91 13.267 17.872 25.780 1.00 36.19 C ATOM 661 CG1 VAL A 91 13.629 17.345 27.159 1.00 35.86 C ATOM 662 CG2 VAL A 91 12.906 16.757 24.811 1.00 38.92 C ATOM 663 N GLU A 92 13.092 20.355 24.234 1.00 31.11 N ATOM 664 CA GLU A 92 13.086 21.238 23.079 1.00 34.18 C ATOM 665 C GLU A 92 14.222 20.825 22.088 1.00 29.74 C ATOM 666 O GLU A 92 15.347 21.286 22.201 1.00 26.72 O ATOM 667 CB GLU A 92 13.223 22.690 23.529 1.00 38.96 C ATOM 668 CG GLU A 92 12.630 23.674 22.539 1.00 49.67 C ATOM 669 CD GLU A 92 13.423 24.985 22.428 1.00 64.38 C ATOM 670 OE1 GLU A 92 13.456 25.547 21.303 1.00 77.38 O ATOM 671 OE2 GLU A 92 13.994 25.484 23.453 1.00 61.37 O ATOM 672 N PRO A 93 13.894 19.942 21.136 1.00 30.27 N ATOM 673 CA PRO A 93 14.845 19.489 20.142 1.00 29.71 C ATOM 674 C PRO A 93 14.945 20.496 18.942 1.00 32.10 C ATOM 675 O PRO A 93 13.946 21.063 18.481 1.00 24.97 O ATOM 676 CB PRO A 93 14.286 18.143 19.774 1.00 31.29 C ATOM 677 CG PRO A 93 12.811 18.374 19.800 1.00 34.60 C ATOM 678 CD PRO A 93 12.608 19.243 21.013 1.00 28.91 C ATOM 679 N LYS A 94 16.155 20.726 18.452 1.00 27.67 N ATOM 680 CA LYS A 94 16.345 21.709 17.409 1.00 29.87 C ATOM 681 C LYS A 94 17.530 21.211 16.625 1.00 29.39 C ATOM 682 O LYS A 94 18.513 20.679 17.203 1.00 24.52 O ATOM 683 CB LYS A 94 16.689 23.134 17.960 1.00 32.96 C ATOM 684 CG LYS A 94 15.659 23.761 18.885 1.00 40.48 C ATOM 685 CD LYS A 94 15.968 25.207 19.289 1.00 46.77 C ATOM 686 CE LYS A 94 16.601 25.289 20.672 1.00 50.32 C ATOM 687 NZ LYS A 94 16.588 26.658 21.239 1.00 56.09 N ATOM 688 N ARG A 95 17.511 21.463 15.325 1.00 27.95 N ATOM 689 CA ARG A 95 18.663 21.079 14.495 1.00 28.66 C ATOM 690 C ARG A 95 19.848 21.903 14.990 1.00 27.98 C ATOM 691 O ARG A 95 19.711 23.099 15.319 1.00 28.43 O ATOM 692 CB ARG A 95 18.330 21.273 13.012 1.00 31.84 C ATOM 693 CG ARG A 95 17.286 20.252 12.565 1.00 30.98 C ATOM 694 CD ARG A 95 16.870 20.495 11.184 1.00 32.60 C ATOM 695 NE ARG A 95 15.615 19.810 10.971 1.00 34.89 N ATOM 696 CZ ARG A 95 15.458 18.667 10.319 1.00 35.08 C ATOM 697 NH1 ARG A 95 16.473 18.031 9.740 1.00 33.59 N ATOM 698 NH2 ARG A 95 14.235 18.169 10.216 1.00 38.45 N ATOM 699 N ALA A 96 21.001 21.265 15.088 1.00 29.09 N ATOM 700 CA ALA A 96 22.153 21.835 15.810 1.00 31.15 C ATOM 701 C ALA A 96 22.809 22.844 14.886 1.00 32.65 C ATOM 702 O ALA A 96 23.042 22.529 13.714 1.00 33.18 O ATOM 703 CB ALA A 96 23.155 20.732 16.171 1.00 30.90 C ATOM 704 N VAL A 97 23.104 24.042 15.379 1.00 34.51 N ATOM 705 CA VAL A 97 23.968 24.954 14.588 1.00 34.85 C ATOM 706 C VAL A 97 25.396 24.636 14.919 1.00 31.05 C ATOM 707 O VAL A 97 25.719 24.488 16.084 1.00 30.08 O ATOM 708 CB VAL A 97 23.638 26.429 14.866 1.00 41.66 C ATOM 709 CG1 VAL A 97 24.381 27.337 13.878 1.00 40.88 C ATOM 710 CG2 VAL A 97 22.119 26.631 14.733 1.00 44.43 C ATOM 711 N ALA A 98 26.241 24.490 13.908 1.00 33.07 N ATOM 712 CA ALA A 98 27.666 24.185 14.095 1.00 31.84 C ATOM 713 C ALA A 98 28.326 25.209 14.915 1.00 31.64 C ATOM 714 O ALA A 98 28.008 26.400 14.820 1.00 27.55 O ATOM 715 CB ALA A 98 28.404 24.090 12.757 1.00 36.85 C ATOM 716 N ARG A 99 29.334 24.762 15.625 1.00 33.56 N ATOM 717 CA ARG A 99 30.074 25.624 16.553 1.00 34.76 C ATOM 718 C ARG A 99 30.740 26.770 15.838 1.00 29.85 C ATOM 719 O ARG A 99 30.805 27.889 16.350 1.00 27.02 O ATOM 720 CB ARG A 99 31.167 24.861 17.280 1.00 40.01 C ATOM 721 CG ARG A 99 30.751 23.541 17.899 1.00 43.38 C ATOM 722 CD ARG A 99 31.915 22.561 17.898 1.00 49.54 C ATOM 723 NE ARG A 99 31.447 21.175 17.841 1.00 53.02 N ATOM 724 CZ ARG A 99 31.836 20.205 18.639 1.00 51.08 C ATOM 725 NH1 ARG A 99 32.720 20.411 19.592 1.00 60.65 N ATOM 726 NH2 ARG A 99 31.329 18.998 18.482 1.00 58.63 N ATOM 727 N GLU A 100 31.169 26.531 14.627 1.00 29.69 N ATOM 728 CA GLU A 100 31.863 27.565 13.848 1.00 35.98 C ATOM 729 C GLU A 100 30.968 28.703 13.326 1.00 32.66 C ATOM 730 O GLU A 100 31.469 29.712 12.870 1.00 32.74 O ATOM 731 CB GLU A 100 32.793 26.982 12.725 1.00 41.49 C ATOM 732 CG GLU A 100 32.455 25.651 12.048 1.00 54.56 C ATOM 733 CD GLU A 100 32.631 24.421 12.942 1.00 54.31 C ATOM 734 OE1 GLU A 100 33.785 24.069 13.324 1.00 54.88 O ATOM 735 OE2 GLU A 100 31.577 23.839 13.293 1.00 54.32 O ATOM 736 N GLU A 101 29.653 28.541 13.406 1.00 33.38 N ATOM 737 CA GLU A 101 28.716 29.557 13.057 1.00 36.38 C ATOM 738 C GLU A 101 27.820 29.995 14.244 1.00 35.32 C ATOM 739 O GLU A 101 26.858 30.719 14.037 1.00 38.22 O ATOM 740 CB GLU A 101 27.798 29.059 11.942 1.00 41.36 C ATOM 741 CG GLU A 101 28.483 28.074 11.006 1.00 47.68 C ATOM 742 CD GLU A 101 27.783 27.891 9.701 1.00 56.76 C ATOM 743 OE1 GLU A 101 26.603 28.294 9.591 1.00 60.21 O ATOM 744 OE2 GLU A 101 28.452 27.327 8.804 1.00 64.88 O ATOM 745 N ASER A 102 28.129 29.572 15.447 0.50 30.73 N ATOM 746 N BSER A 102 28.132 29.528 15.448 0.50 31.98 N ATOM 747 CA ASER A 102 27.246 29.805 16.558 0.50 31.75 C ATOM 748 CA BSER A 102 27.300 29.791 16.605 0.50 33.69 C ATOM 749 C ASER A 102 27.464 31.191 17.183 0.50 29.96 C ATOM 750 C BSER A 102 27.312 31.281 16.915 0.50 31.98 C ATOM 751 O ASER A 102 26.785 31.548 18.123 0.50 25.63 O ATOM 752 O BSER A 102 26.282 31.830 17.229 0.50 30.76 O ATOM 753 CB ASER A 102 27.398 28.666 17.579 0.50 29.33 C ATOM 754 CB BSER A 102 27.669 28.924 17.850 0.50 31.03 C ATOM 755 OG ASER A 102 26.847 27.471 17.035 0.50 26.76 O ATOM 756 OG BSER A 102 29.059 28.897 18.160 0.50 29.98 O ATOM 757 N GLY A 103 28.432 31.945 16.686 1.00 33.38 N ATOM 758 CA GLY A 103 28.561 33.353 17.021 1.00 37.72 C ATOM 759 C GLY A 103 27.980 34.367 16.048 1.00 35.50 C ATOM 760 O GLY A 103 27.943 35.503 16.378 1.00 37.28 O ATOM 761 N LYS A 104 27.592 33.968 14.851 1.00 32.57 N ATOM 762 CA LYS A 104 26.870 34.805 13.940 1.00 38.71 C ATOM 763 C LYS A 104 25.597 35.361 14.559 1.00 41.43 C ATOM 764 O LYS A 104 24.868 34.642 15.225 1.00 35.56 O ATOM 765 CB LYS A 104 26.378 34.008 12.736 1.00 49.91 C ATOM 766 CG LYS A 104 27.416 33.660 11.729 1.00 61.09 C ATOM 767 CD LYS A 104 26.804 32.838 10.610 1.00 71.38 C ATOM 768 CE LYS A 104 27.919 32.237 9.771 1.00 80.87 C ATOM 769 NZ LYS A 104 27.394 31.269 8.768 1.00 92.53 N ATOM 770 N PRO A 105 25.297 36.632 14.283 1.00 43.31 N ATOM 771 CA PRO A 105 24.048 37.238 14.770 1.00 41.20 C ATOM 772 C PRO A 105 22.824 36.436 14.369 1.00 36.12 C ATOM 773 O PRO A 105 22.724 35.964 13.249 1.00 33.44 O ATOM 774 CB PRO A 105 24.048 38.628 14.101 1.00 44.40 C ATOM 775 CG PRO A 105 25.509 38.939 13.866 1.00 46.00 C ATOM 776 CD PRO A 105 26.247 37.632 13.742 1.00 42.48 C ATOM 777 N GLY A 106 21.901 36.221 15.289 1.00 40.19 N ATOM 778 CA GLY A 106 20.710 35.444 14.890 1.00 40.55 C ATOM 779 C GLY A 106 20.837 33.921 14.827 1.00 38.26 C ATOM 780 O GLY A 106 19.843 33.230 14.639 1.00 36.63 O ATOM 781 N ALA A 107 22.032 33.370 15.051 1.00 34.64 N ATOM 782 CA ALA A 107 22.253 31.975 14.699 1.00 33.38 C ATOM 783 C ALA A 107 21.322 31.002 15.466 1.00 29.86 C ATOM 784 O ALA A 107 20.867 30.028 14.893 1.00 30.00 O ATOM 785 CB ALA A 107 23.726 31.589 14.906 1.00 35.73 C ATOM 786 N HIS A 108 21.012 31.281 16.723 1.00 27.58 N ATOM 787 CA HIS A 108 20.238 30.360 17.522 1.00 32.01 C ATOM 788 C HIS A 108 18.824 30.809 17.647 1.00 33.56 C ATOM 789 O HIS A 108 18.083 30.199 18.379 1.00 31.45 O ATOM 790 CB HIS A 108 20.911 30.105 18.879 1.00 31.89 C ATOM 791 CG HIS A 108 22.236 29.434 18.710 1.00 33.62 C ATOM 792 ND1 HIS A 108 23.299 29.664 19.533 1.00 33.62 N ATOM 793 CD2 HIS A 108 22.705 28.647 17.715 1.00 37.47 C ATOM 794 CE1 HIS A 108 24.350 29.017 19.091 1.00 32.73 C ATOM 795 NE2 HIS A 108 24.019 28.382 17.991 1.00 35.94 N ATOM 796 N VAL A 109 18.422 31.826 16.896 1.00 31.75 N ATOM 797 CA VAL A 109 17.082 32.310 17.042 1.00 33.54 C ATOM 798 C VAL A 109 16.132 31.452 16.237 1.00 36.81 C ATOM 799 O VAL A 109 16.384 31.186 15.097 1.00 40.75 O ATOM 800 CB VAL A 109 16.962 33.741 16.598 1.00 35.67 C ATOM 801 CG1 VAL A 109 15.515 34.230 16.774 1.00 35.54 C ATOM 802 CG2 VAL A 109 17.944 34.563 17.429 1.00 40.52 C ATOM 803 N THR A 110 15.031 31.069 16.865 1.00 34.93 N ATOM 804 CA THR A 110 14.121 30.108 16.356 1.00 42.53 C ATOM 805 C THR A 110 12.945 30.886 15.775 1.00 36.61 C ATOM 806 O THR A 110 12.293 31.545 16.502 1.00 35.17 O ATOM 807 CB THR A 110 13.659 29.192 17.520 1.00 40.78 C ATOM 808 OG1 THR A 110 14.784 28.451 17.968 1.00 47.42 O ATOM 809 CG2 THR A 110 12.658 28.229 17.054 1.00 50.23 C ATOM 810 N VAL A 111 12.716 30.837 14.478 1.00 34.86 N ATOM 811 CA VAL A 111 11.579 31.561 13.821 1.00 34.91 C ATOM 812 C VAL A 111 10.905 30.671 12.798 1.00 32.07 C ATOM 813 O VAL A 111 11.445 29.658 12.371 1.00 27.86 O ATOM 814 CB VAL A 111 12.011 32.907 13.132 1.00 38.07 C ATOM 815 CG1 VAL A 111 12.513 33.880 14.149 1.00 38.36 C ATOM 816 CG2 VAL A 111 13.098 32.701 12.064 1.00 37.66 C ATOM 817 N LYS A 112 9.698 31.064 12.394 1.00 32.76 N ATOM 818 CA LYS A 112 8.911 30.323 11.443 1.00 32.19 C ATOM 819 C LYS A 112 8.978 30.966 10.085 1.00 29.20 C ATOM 820 O LYS A 112 8.308 30.515 9.148 1.00 30.73 O ATOM 821 CB LYS A 112 7.431 30.311 11.884 1.00 35.90 C ATOM 822 CG LYS A 112 7.260 29.583 13.200 1.00 38.64 C ATOM 823 CD LYS A 112 5.811 29.434 13.640 1.00 44.13 C ATOM 824 CE LYS A 112 5.770 28.707 14.983 1.00 48.78 C ATOM 825 NZ LYS A 112 4.481 28.989 15.653 1.00 58.57 N ATOM 826 N LYS A 113 9.721 32.043 9.966 1.00 28.92 N ATOM 827 CA LYS A 113 9.709 32.815 8.713 1.00 31.40 C ATOM 828 C LYS A 113 11.021 32.732 7.994 1.00 30.78 C ATOM 829 O LYS A 113 12.060 32.895 8.593 1.00 33.29 O ATOM 830 CB LYS A 113 9.407 34.252 9.056 1.00 35.11 C ATOM 831 CG LYS A 113 9.144 35.172 7.891 1.00 38.56 C ATOM 832 CD LYS A 113 8.834 36.552 8.424 1.00 43.14 C ATOM 833 CE LYS A 113 7.780 37.226 7.576 1.00 55.08 C ATOM 834 NZ LYS A 113 7.262 38.384 8.337 1.00 59.24 N ATOM 835 N LEU A 114 10.951 32.571 6.686 1.00 28.52 N ATOM 836 CA LEU A 114 12.078 32.428 5.858 1.00 31.27 C ATOM 837 C LEU A 114 12.182 33.631 4.916 1.00 35.04 C ATOM 838 O LEU A 114 11.195 34.011 4.298 1.00 35.32 O ATOM 839 CB LEU A 114 11.880 31.125 5.107 1.00 32.07 C ATOM 840 CG LEU A 114 13.090 30.659 4.297 1.00 34.00 C ATOM 841 CD1 LEU A 114 14.131 29.985 5.204 1.00 36.40 C ATOM 842 CD2 LEU A 114 12.679 29.742 3.170 1.00 31.05 C ATOM 843 N PHE A 115 13.376 34.202 4.789 1.00 32.62 N ATOM 844 CA PHE A 115 13.700 35.225 3.767 1.00 31.97 C ATOM 845 C PHE A 115 14.218 34.479 2.566 1.00 34.31 C ATOM 846 O PHE A 115 14.987 33.537 2.714 1.00 30.62 O ATOM 847 CB PHE A 115 14.779 36.165 4.261 1.00 32.51 C ATOM 848 CG PHE A 115 15.497 36.942 3.136 1.00 37.28 C ATOM 849 CD1 PHE A 115 14.919 38.064 2.545 1.00 36.79 C ATOM 850 CD2 PHE A 115 16.753 36.561 2.701 1.00 37.25 C ATOM 851 CE1 PHE A 115 15.577 38.778 1.539 1.00 40.41 C ATOM 852 CE2 PHE A 115 17.424 37.261 1.675 1.00 41.01 C ATOM 853 CZ PHE A 115 16.842 38.388 1.104 1.00 38.23 C ATOM 854 N VAL A 116 13.736 34.852 1.379 1.00 34.05 N ATOM 855 CA VAL A 116 14.180 34.245 0.132 1.00 33.36 C ATOM 856 C VAL A 116 14.619 35.361 -0.833 1.00 31.83 C ATOM 857 O VAL A 116 13.795 36.086 -1.368 1.00 36.46 O ATOM 858 CB VAL A 116 13.048 33.401 -0.511 1.00 36.15 C ATOM 859 CG1 VAL A 116 13.573 32.609 -1.715 1.00 35.08 C ATOM 860 CG2 VAL A 116 12.409 32.461 0.523 1.00 36.98 C ATOM 861 N GLY A 117 15.917 35.518 -1.022 1.00 31.49 N ATOM 862 CA GLY A 117 16.428 36.551 -1.923 1.00 31.79 C ATOM 863 C GLY A 117 17.052 35.993 -3.180 1.00 31.92 C ATOM 864 O GLY A 117 17.263 34.780 -3.292 1.00 32.59 O ATOM 865 N GLY A 118 17.380 36.893 -4.096 1.00 34.39 N ATOM 866 CA GLY A 118 18.011 36.546 -5.375 1.00 35.41 C ATOM 867 C GLY A 118 17.001 36.021 -6.394 1.00 36.83 C ATOM 868 O GLY A 118 17.379 35.349 -7.374 1.00 32.59 O ATOM 869 N ILE A 119 15.724 36.328 -6.180 1.00 36.98 N ATOM 870 CA ILE A 119 14.686 35.748 -7.040 1.00 38.65 C ATOM 871 C ILE A 119 14.248 36.694 -8.133 1.00 38.66 C ATOM 872 O ILE A 119 13.408 36.328 -8.975 1.00 43.79 O ATOM 873 CB ILE A 119 13.475 35.219 -6.234 1.00 37.26 C ATOM 874 CG1 ILE A 119 12.876 36.283 -5.334 1.00 35.18 C ATOM 875 CG2 ILE A 119 13.908 34.023 -5.411 1.00 40.34 C ATOM 876 CD1 ILE A 119 11.620 35.832 -4.619 1.00 40.15 C ATOM 877 N LYS A 120 14.801 37.905 -8.135 1.00 41.86 N ATOM 878 CA LYS A 120 14.637 38.860 -9.263 1.00 43.83 C ATOM 879 C LYS A 120 13.164 39.149 -9.541 1.00 43.15 C ATOM 880 O LYS A 120 12.313 38.971 -8.665 1.00 40.85 O ATOM 881 CB LYS A 120 15.353 38.365 -10.528 1.00 42.80 C ATOM 882 CG LYS A 120 16.716 37.711 -10.300 1.00 53.46 C ATOM 883 CD LYS A 120 17.765 38.608 -9.652 1.00 58.75 C ATOM 884 CE LYS A 120 18.731 39.250 -10.651 1.00 72.89 C ATOM 885 NZ LYS A 120 19.602 38.268 -11.356 1.00 75.05 N ATOM 886 N GLU A 121 12.853 39.556 -10.766 1.00 44.94 N ATOM 887 CA GLU A 121 11.495 40.033 -11.100 1.00 43.83 C ATOM 888 C GLU A 121 10.503 39.004 -11.648 1.00 41.43 C ATOM 889 O GLU A 121 9.305 39.254 -11.704 1.00 43.26 O ATOM 890 CB GLU A 121 11.646 41.196 -12.105 1.00 47.94 C ATOM 891 CG GLU A 121 12.287 42.393 -11.463 1.00 52.29 C ATOM 892 CD GLU A 121 11.966 43.661 -12.215 1.00 66.27 C ATOM 893 OE1 GLU A 121 10.762 44.016 -12.334 1.00 67.86 O ATOM 894 OE2 GLU A 121 12.928 44.296 -12.684 1.00 63.72 O ATOM 895 N ASP A 122 11.014 37.894 -12.138 1.00 42.85 N ATOM 896 CA ASP A 122 10.196 36.892 -12.764 1.00 42.53 C ATOM 897 C ASP A 122 9.629 35.900 -11.716 1.00 48.45 C ATOM 898 O ASP A 122 8.738 35.136 -12.037 1.00 45.22 O ATOM 899 CB ASP A 122 10.984 36.167 -13.853 1.00 42.17 C ATOM 900 CG ASP A 122 12.237 35.495 -13.349 1.00 47.74 C ATOM 901 OD1 ASP A 122 12.641 35.635 -12.148 1.00 46.09 O ATOM 902 OD2 ASP A 122 12.841 34.808 -14.187 1.00 51.64 O ATOM 903 N THR A 123 10.113 35.925 -10.472 1.00 43.28 N ATOM 904 CA THR A 123 9.709 34.896 -9.497 1.00 41.79 C ATOM 905 C THR A 123 8.395 35.251 -8.785 1.00 40.56 C ATOM 906 O THR A 123 8.183 36.358 -8.298 1.00 39.47 O ATOM 907 CB THR A 123 10.842 34.562 -8.527 1.00 39.40 C ATOM 908 OG1 THR A 123 11.970 34.046 -9.282 1.00 38.79 O ATOM 909 CG2 THR A 123 10.388 33.457 -7.534 1.00 41.18 C ATOM 910 N GLU A 124 7.520 34.256 -8.739 1.00 42.09 N ATOM 911 CA GLU A 124 6.159 34.379 -8.273 1.00 47.93 C ATOM 912 C GLU A 124 5.930 33.602 -6.973 1.00 39.59 C ATOM 913 O GLU A 124 6.677 32.687 -6.654 1.00 38.99 O ATOM 914 CB GLU A 124 5.196 33.746 -9.314 1.00 52.01 C ATOM 915 CG GLU A 124 5.288 34.286 -10.724 1.00 54.17 C ATOM 916 CD GLU A 124 4.540 35.577 -10.888 1.00 61.40 C ATOM 917 OE1 GLU A 124 4.328 36.314 -9.880 1.00 65.04 O ATOM 918 OE2 GLU A 124 4.156 35.838 -12.045 1.00 70.15 O ATOM 919 N GLU A 125 4.817 33.913 -6.315 1.00 46.30 N ATOM 920 CA GLU A 125 4.324 33.133 -5.159 1.00 45.59 C ATOM 921 C GLU A 125 4.344 31.649 -5.448 1.00 45.93 C ATOM 922 O GLU A 125 4.966 30.839 -4.708 1.00 44.60 O ATOM 923 CB GLU A 125 2.938 33.610 -4.787 1.00 51.56 C ATOM 924 CG GLU A 125 2.449 33.005 -3.490 1.00 50.94 C ATOM 925 CD GLU A 125 1.294 33.710 -2.854 1.00 45.39 C ATOM 926 OE1 GLU A 125 1.184 34.933 -2.899 1.00 51.76 O ATOM 927 OE2 GLU A 125 0.517 33.018 -2.188 1.00 46.06 O ATOM 928 N HIS A 126 3.789 31.287 -6.597 1.00 38.98 N ATOM 929 CA HIS A 126 3.620 29.897 -6.907 1.00 38.03 C ATOM 930 C HIS A 126 4.921 29.183 -7.064 1.00 39.21 C ATOM 931 O HIS A 126 5.022 27.998 -6.727 1.00 38.69 O ATOM 932 CB HIS A 126 2.695 29.699 -8.127 1.00 39.61 C ATOM 933 CG HIS A 126 3.384 29.842 -9.444 1.00 35.27 C ATOM 934 ND1 HIS A 126 3.345 31.003 -10.184 1.00 36.09 N ATOM 935 CD2 HIS A 126 4.095 28.957 -10.170 1.00 37.25 C ATOM 936 CE1 HIS A 126 4.053 30.852 -11.285 1.00 33.88 C ATOM 937 NE2 HIS A 126 4.524 29.618 -11.300 1.00 40.76 N ATOM 938 N HIS A 127 5.941 29.867 -7.591 1.00 42.83 N ATOM 939 CA HIS A 127 7.276 29.283 -7.593 1.00 37.90 C ATOM 940 C HIS A 127 7.709 28.872 -6.169 1.00 33.91 C ATOM 941 O HIS A 127 8.203 27.773 -5.977 1.00 36.31 O ATOM 942 CB HIS A 127 8.319 30.217 -8.234 1.00 45.63 C ATOM 943 CG HIS A 127 8.228 30.305 -9.727 1.00 44.20 C ATOM 944 ND1 HIS A 127 7.724 31.409 -10.375 1.00 40.86 N ATOM 945 CD2 HIS A 127 8.556 29.416 -10.695 1.00 46.33 C ATOM 946 CE1 HIS A 127 7.750 31.206 -11.676 1.00 44.96 C ATOM 947 NE2 HIS A 127 8.256 30.006 -11.899 1.00 49.38 N ATOM 948 N LEU A 128 7.496 29.755 -5.211 1.00 35.54 N ATOM 949 CA LEU A 128 7.986 29.531 -3.856 1.00 38.77 C ATOM 950 C LEU A 128 7.143 28.453 -3.199 1.00 43.01 C ATOM 951 O LEU A 128 7.707 27.464 -2.663 1.00 38.52 O ATOM 952 CB LEU A 128 7.940 30.798 -3.020 1.00 39.76 C ATOM 953 CG LEU A 128 8.732 32.037 -3.437 1.00 39.88 C ATOM 954 CD1 LEU A 128 8.618 33.135 -2.364 1.00 39.71 C ATOM 955 CD2 LEU A 128 10.153 31.664 -3.745 1.00 37.17 C ATOM 956 N ARG A 129 5.802 28.594 -3.305 1.00 42.73 N ATOM 957 CA ARG A 129 4.882 27.589 -2.768 1.00 43.00 C ATOM 958 C ARG A 129 5.347 26.247 -3.195 1.00 42.83 C ATOM 959 O ARG A 129 5.498 25.348 -2.386 1.00 42.08 O ATOM 960 CB ARG A 129 3.414 27.828 -3.226 1.00 47.74 C ATOM 961 CG ARG A 129 2.413 26.734 -2.856 1.00 50.93 C ATOM 962 CD ARG A 129 2.233 25.643 -3.942 1.00 51.50 C ATOM 963 NE ARG A 129 1.460 26.070 -5.124 1.00 52.57 N ATOM 964 CZ ARG A 129 1.856 26.105 -6.412 1.00 60.38 C ATOM 965 NH1 ARG A 129 1.009 26.542 -7.355 1.00 65.34 N ATOM 966 NH2 ARG A 129 3.063 25.699 -6.791 1.00 66.07 N ATOM 967 N ASP A 130 5.602 26.128 -4.489 1.00 42.07 N ATOM 968 CA ASP A 130 5.998 24.903 -5.096 1.00 37.53 C ATOM 969 C ASP A 130 7.266 24.331 -4.566 1.00 44.49 C ATOM 970 O ASP A 130 7.372 23.141 -4.269 1.00 39.70 O ATOM 971 CB ASP A 130 6.267 25.173 -6.554 1.00 44.66 C ATOM 972 CG ASP A 130 5.912 24.066 -7.372 1.00 44.94 C ATOM 973 OD1 ASP A 130 4.691 23.876 -7.529 1.00 36.12 O ATOM 974 OD2 ASP A 130 6.832 23.391 -7.842 1.00 53.70 O ATOM 975 N TYR A 131 8.291 25.167 -4.596 1.00 40.04 N ATOM 976 CA TYR A 131 9.603 24.726 -4.194 1.00 39.72 C ATOM 977 C TYR A 131 9.612 24.312 -2.700 1.00 34.04 C ATOM 978 O TYR A 131 10.279 23.379 -2.331 1.00 43.17 O ATOM 979 CB TYR A 131 10.561 25.872 -4.415 1.00 35.17 C ATOM 980 CG TYR A 131 11.909 25.498 -3.982 1.00 37.06 C ATOM 981 CD1 TYR A 131 12.743 24.825 -4.838 1.00 39.59 C ATOM 982 CD2 TYR A 131 12.348 25.782 -2.726 1.00 35.13 C ATOM 983 CE1 TYR A 131 13.986 24.470 -4.459 1.00 42.73 C ATOM 984 CE2 TYR A 131 13.602 25.406 -2.327 1.00 40.89 C ATOM 985 CZ TYR A 131 14.412 24.770 -3.204 1.00 38.55 C ATOM 986 OH TYR A 131 15.644 24.399 -2.829 1.00 43.32 O ATOM 987 N PHE A 132 8.901 25.049 -1.871 1.00 36.92 N ATOM 988 CA PHE A 132 9.004 24.936 -0.437 1.00 40.36 C ATOM 989 C PHE A 132 7.911 24.077 0.242 1.00 44.12 C ATOM 990 O PHE A 132 8.130 23.592 1.357 1.00 37.25 O ATOM 991 CB PHE A 132 8.983 26.340 0.194 1.00 41.06 C ATOM 992 CG PHE A 132 10.283 27.074 0.075 1.00 39.16 C ATOM 993 CD1 PHE A 132 11.406 26.612 0.734 1.00 37.90 C ATOM 994 CD2 PHE A 132 10.387 28.233 -0.671 1.00 38.44 C ATOM 995 CE1 PHE A 132 12.635 27.283 0.642 1.00 37.01 C ATOM 996 CE2 PHE A 132 11.597 28.903 -0.787 1.00 33.56 C ATOM 997 CZ PHE A 132 12.728 28.432 -0.137 1.00 32.93 C ATOM 998 N GLU A 133 6.754 23.895 -0.404 1.00 43.73 N ATOM 999 CA GLU A 133 5.661 23.103 0.201 1.00 50.94 C ATOM 1000 C GLU A 133 6.126 21.717 0.715 1.00 44.56 C ATOM 1001 O GLU A 133 5.580 21.228 1.682 1.00 38.58 O ATOM 1002 CB GLU A 133 4.451 22.925 -0.749 1.00 50.23 C ATOM 1003 CG GLU A 133 4.753 22.069 -1.989 1.00 55.26 C ATOM 1004 CD GLU A 133 3.611 22.012 -3.012 1.00 64.97 C ATOM 1005 OE1 GLU A 133 2.550 22.664 -2.775 1.00 62.28 O ATOM 1006 OE2 GLU A 133 3.795 21.317 -4.060 1.00 58.14 O ATOM 1007 N GLU A 134 7.128 21.093 0.090 1.00 44.41 N ATOM 1008 CA GLU A 134 7.527 19.743 0.494 1.00 52.23 C ATOM 1009 C GLU A 134 8.150 19.723 1.925 1.00 48.59 C ATOM 1010 O GLU A 134 8.214 18.669 2.549 1.00 41.84 O ATOM 1011 CB GLU A 134 8.433 19.045 -0.562 1.00 64.65 C ATOM 1012 CG GLU A 134 9.943 19.102 -0.279 1.00 76.84 C ATOM 1013 CD GLU A 134 10.812 18.508 -1.384 1.00 83.09 C ATOM 1014 OE1 GLU A 134 10.689 18.942 -2.550 1.00 85.73 O ATOM 1015 OE2 GLU A 134 11.644 17.622 -1.086 1.00 81.59 O ATOM 1016 N TYR A 135 8.559 20.877 2.438 1.00 42.04 N ATOM 1017 CA TYR A 135 9.276 20.946 3.709 1.00 44.43 C ATOM 1018 C TYR A 135 8.396 21.065 4.948 1.00 42.38 C ATOM 1019 O TYR A 135 8.868 20.929 6.047 1.00 41.90 O ATOM 1020 CB TYR A 135 10.172 22.167 3.704 1.00 40.87 C ATOM 1021 CG TYR A 135 11.379 22.051 2.808 1.00 41.94 C ATOM 1022 CD1 TYR A 135 12.568 21.519 3.292 1.00 40.27 C ATOM 1023 CD2 TYR A 135 11.361 22.547 1.485 1.00 41.89 C ATOM 1024 CE1 TYR A 135 13.721 21.473 2.498 1.00 40.51 C ATOM 1025 CE2 TYR A 135 12.492 22.481 0.684 1.00 42.44 C ATOM 1026 CZ TYR A 135 13.671 21.947 1.223 1.00 40.28 C ATOM 1027 OH TYR A 135 14.787 21.872 0.480 1.00 43.21 O ATOM 1028 N GLY A 136 7.131 21.358 4.779 1.00 41.97 N ATOM 1029 CA GLY A 136 6.272 21.510 5.928 1.00 42.24 C ATOM 1030 C GLY A 136 5.101 22.306 5.485 1.00 47.72 C ATOM 1031 O GLY A 136 4.952 22.622 4.300 1.00 52.28 O ATOM 1032 N LYS A 137 4.302 22.704 6.457 1.00 52.13 N ATOM 1033 CA LYS A 137 3.042 23.395 6.216 1.00 46.20 C ATOM 1034 C LYS A 137 3.271 24.880 6.118 1.00 39.49 C ATOM 1035 O LYS A 137 3.780 25.493 7.050 1.00 43.88 O ATOM 1036 CB LYS A 137 2.089 23.048 7.370 1.00 51.27 C ATOM 1037 CG LYS A 137 0.625 23.147 7.064 1.00 53.01 C ATOM 1038 CD LYS A 137 0.196 22.008 6.150 1.00 65.80 C ATOM 1039 CE LYS A 137 -1.257 22.152 5.697 1.00 70.59 C ATOM 1040 NZ LYS A 137 -2.219 22.483 6.792 1.00 66.19 N ATOM 1041 N ILE A 138 2.933 25.482 4.971 1.00 37.74 N ATOM 1042 CA ILE A 138 3.197 26.904 4.747 1.00 36.09 C ATOM 1043 C ILE A 138 2.015 27.687 5.196 1.00 39.10 C ATOM 1044 O ILE A 138 0.912 27.318 4.832 1.00 52.19 O ATOM 1045 CB ILE A 138 3.519 27.186 3.251 1.00 40.79 C ATOM 1046 CG1 ILE A 138 4.940 26.729 2.909 1.00 40.79 C ATOM 1047 CG2 ILE A 138 3.374 28.660 2.886 1.00 39.40 C ATOM 1048 CD1 ILE A 138 5.115 26.448 1.432 1.00 42.30 C ATOM 1049 N ASP A 139 2.191 28.772 5.954 1.00 43.39 N ATOM 1050 CA ASP A 139 1.055 29.595 6.334 1.00 45.40 C ATOM 1051 C ASP A 139 0.864 30.594 5.232 1.00 57.24 C ATOM 1052 O ASP A 139 -0.219 30.650 4.603 1.00 53.48 O ATOM 1053 CB ASP A 139 1.201 30.329 7.692 1.00 42.13 C ATOM 1054 CG ASP A 139 0.831 29.426 8.899 1.00 46.89 C ATOM 1055 OD1 ASP A 139 0.549 28.218 8.733 1.00 43.43 O ATOM 1056 OD2 ASP A 139 0.860 29.925 10.036 1.00 46.17 O ATOM 1057 N THR A 140 1.923 31.381 5.006 1.00 50.60 N ATOM 1058 CA THR A 140 1.868 32.511 4.108 1.00 48.50 C ATOM 1059 C THR A 140 3.096 32.606 3.223 1.00 52.28 C ATOM 1060 O THR A 140 4.082 31.899 3.460 1.00 44.20 O ATOM 1061 CB THR A 140 1.720 33.786 4.867 1.00 45.26 C ATOM 1062 OG1 THR A 140 2.989 34.121 5.411 1.00 58.29 O ATOM 1063 CG2 THR A 140 0.678 33.604 5.968 1.00 52.97 C ATOM 1064 N ILE A 141 2.962 33.408 2.164 1.00 47.47 N ATOM 1065 CA ILE A 141 4.033 33.691 1.190 1.00 46.15 C ATOM 1066 C ILE A 141 3.808 35.102 0.700 1.00 48.69 C ATOM 1067 O ILE A 141 2.705 35.390 0.215 1.00 49.40 O ATOM 1068 CB ILE A 141 4.048 32.771 -0.037 1.00 46.41 C ATOM 1069 CG1 ILE A 141 4.250 31.319 0.340 1.00 47.35 C ATOM 1070 CG2 ILE A 141 5.183 33.192 -0.995 1.00 46.44 C ATOM 1071 CD1 ILE A 141 3.970 30.308 -0.747 1.00 48.38 C ATOM 1072 N GLU A 142 4.822 35.957 0.834 1.00 43.82 N ATOM 1073 CA GLU A 142 4.783 37.356 0.393 1.00 46.31 C ATOM 1074 C GLU A 142 5.959 37.632 -0.544 1.00 47.27 C ATOM 1075 O GLU A 142 7.119 37.400 -0.187 1.00 42.34 O ATOM 1076 CB GLU A 142 4.921 38.343 1.562 1.00 53.23 C ATOM 1077 CG GLU A 142 4.188 38.012 2.854 1.00 60.71 C ATOM 1078 CD GLU A 142 4.870 38.638 4.064 1.00 68.76 C ATOM 1079 OE1 GLU A 142 5.365 37.878 4.938 1.00 65.87 O ATOM 1080 OE2 GLU A 142 4.941 39.893 4.122 1.00 71.88 O ATOM 1081 N ILE A 143 5.654 38.142 -1.729 1.00 47.32 N ATOM 1082 CA ILE A 143 6.633 38.672 -2.697 1.00 44.46 C ATOM 1083 C ILE A 143 6.619 40.153 -2.540 1.00 41.95 C ATOM 1084 O ILE A 143 5.555 40.755 -2.540 1.00 49.84 O ATOM 1085 CB ILE A 143 6.210 38.342 -4.145 1.00 48.88 C ATOM 1086 CG1 ILE A 143 6.117 36.826 -4.334 1.00 49.90 C ATOM 1087 CG2 ILE A 143 7.187 38.904 -5.188 1.00 44.35 C ATOM 1088 CD1 ILE A 143 7.446 36.099 -4.232 1.00 48.83 C ATOM 1089 N ILE A 144 7.785 40.750 -2.385 1.00 38.96 N ATOM 1090 CA ILE A 144 7.876 42.153 -2.073 1.00 44.18 C ATOM 1091 C ILE A 144 8.020 42.965 -3.353 1.00 51.73 C ATOM 1092 O ILE A 144 8.762 42.562 -4.274 1.00 50.15 O ATOM 1093 CB ILE A 144 9.051 42.467 -1.155 1.00 45.30 C ATOM 1094 CG1 ILE A 144 9.032 41.515 0.063 1.00 49.31 C ATOM 1095 CG2 ILE A 144 9.032 43.952 -0.765 1.00 43.42 C ATOM 1096 CD1 ILE A 144 7.710 41.488 0.829 1.00 52.77 C ATOM 1097 N THR A 145 7.286 44.081 -3.391 1.00 52.09 N ATOM 1098 CA THR A 145 7.220 44.974 -4.554 1.00 53.93 C ATOM 1099 C THR A 145 7.427 46.377 -4.018 1.00 60.84 C ATOM 1100 O THR A 145 7.245 46.616 -2.813 1.00 61.88 O ATOM 1101 CB THR A 145 5.862 44.882 -5.322 1.00 50.94 C ATOM 1102 OG1 THR A 145 4.786 45.083 -4.409 1.00 48.28 O ATOM 1103 CG2 THR A 145 5.647 43.526 -5.958 1.00 47.73 C ATOM 1104 N ASP A 146 7.832 47.295 -4.900 1.00 70.69 N ATOM 1105 CA ASP A 146 8.023 48.702 -4.531 1.00 74.70 C ATOM 1106 C ASP A 146 6.658 49.294 -4.181 1.00 81.67 C ATOM 1107 O ASP A 146 5.635 48.891 -4.763 1.00 66.74 O ATOM 1108 CB ASP A 146 8.664 49.486 -5.682 1.00 79.13 C ATOM 1109 CG ASP A 146 9.162 50.868 -5.258 1.00 76.28 C ATOM 1110 OD1 ASP A 146 10.085 50.921 -4.425 1.00 77.90 O ATOM 1111 OD2 ASP A 146 8.653 51.892 -5.777 1.00 71.05 O ATOM 1112 N ARG A 147 6.644 50.227 -3.221 1.00 90.62 N ATOM 1113 CA ARG A 147 5.381 50.809 -2.746 1.00 94.82 C ATOM 1114 C ARG A 147 4.686 51.715 -3.791 1.00101.64 C ATOM 1115 O ARG A 147 3.474 51.576 -3.976 1.00 99.06 O ATOM 1116 CB ARG A 147 5.512 51.500 -1.369 1.00 96.37 C ATOM 1117 CG ARG A 147 6.594 52.566 -1.215 1.00 97.15 C ATOM 1118 CD ARG A 147 6.066 53.841 -0.551 1.00 98.46 C ATOM 1119 NE ARG A 147 5.276 53.616 0.673 1.00 97.92 N ATOM 1120 CZ ARG A 147 4.520 54.541 1.282 1.00 94.61 C ATOM 1121 NH1 ARG A 147 4.425 55.783 0.808 1.00 91.63 N ATOM 1122 NH2 ARG A 147 3.847 54.230 2.388 1.00 89.90 N ATOM 1123 N GLN A 148 5.430 52.587 -4.494 1.00104.53 N ATOM 1124 CA GLN A 148 4.828 53.466 -5.534 1.00100.70 C ATOM 1125 C GLN A 148 4.800 52.732 -6.859 1.00 93.09 C ATOM 1126 O GLN A 148 3.725 52.524 -7.423 1.00 91.34 O ATOM 1127 CB GLN A 148 5.541 54.821 -5.720 1.00101.95 C ATOM 1128 CG GLN A 148 6.016 55.491 -4.441 1.00 99.91 C ATOM 1129 CD GLN A 148 7.432 55.084 -4.055 1.00103.92 C ATOM 1130 OE1 GLN A 148 8.234 54.673 -4.905 1.00 99.02 O ATOM 1131 NE2 GLN A 148 7.745 55.188 -2.766 1.00104.07 N ATOM 1132 N SER A 149 5.979 52.325 -7.340 1.00 90.43 N ATOM 1133 CA SER A 149 6.089 51.646 -8.650 1.00 86.57 C ATOM 1134 C SER A 149 5.540 50.196 -8.742 1.00 83.83 C ATOM 1135 O SER A 149 5.277 49.705 -9.842 1.00 81.69 O ATOM 1136 CB SER A 149 7.531 51.716 -9.185 1.00 81.17 C ATOM 1137 OG SER A 149 8.452 51.106 -8.314 1.00 75.53 O ATOM 1138 N GLY A 150 5.362 49.505 -7.615 1.00 83.87 N ATOM 1139 CA GLY A 150 5.020 48.084 -7.648 1.00 75.59 C ATOM 1140 C GLY A 150 5.978 47.259 -8.500 1.00 75.51 C ATOM 1141 O GLY A 150 5.573 46.247 -9.061 1.00 72.83 O ATOM 1142 N LYS A 151 7.237 47.691 -8.623 1.00 74.26 N ATOM 1143 CA LYS A 151 8.297 46.869 -9.224 1.00 71.36 C ATOM 1144 C LYS A 151 8.711 45.815 -8.198 1.00 59.64 C ATOM 1145 O LYS A 151 8.955 46.168 -7.043 1.00 56.77 O ATOM 1146 CB LYS A 151 9.520 47.728 -9.593 1.00 78.97 C ATOM 1147 CG LYS A 151 9.246 48.777 -10.674 1.00 82.66 C ATOM 1148 CD LYS A 151 10.393 48.920 -11.667 1.00 87.34 C ATOM 1149 CE LYS A 151 10.677 47.615 -12.411 1.00 86.74 C ATOM 1150 NZ LYS A 151 11.209 47.805 -13.788 1.00 85.96 N ATOM 1151 N LYS A 152 8.781 44.547 -8.612 1.00 54.69 N ATOM 1152 CA LYS A 152 9.203 43.454 -7.716 1.00 51.40 C ATOM 1153 C LYS A 152 10.648 43.663 -7.322 1.00 51.76 C ATOM 1154 O LYS A 152 11.506 43.879 -8.194 1.00 55.56 O ATOM 1155 CB LYS A 152 9.084 42.116 -8.401 1.00 50.57 C ATOM 1156 CG LYS A 152 7.668 41.576 -8.500 1.00 51.31 C ATOM 1157 CD LYS A 152 7.749 40.261 -9.267 1.00 54.55 C ATOM 1158 CE LYS A 152 6.559 39.334 -9.075 1.00 54.62 C ATOM 1159 NZ LYS A 152 6.846 37.998 -9.691 1.00 55.99 N ATOM 1160 N ARG A 153 10.919 43.608 -6.025 1.00 47.57 N ATOM 1161 CA ARG A 153 12.226 44.002 -5.509 1.00 49.06 C ATOM 1162 C ARG A 153 13.235 42.860 -5.481 1.00 46.93 C ATOM 1163 O ARG A 153 14.385 43.088 -5.192 1.00 49.83 O ATOM 1164 CB ARG A 153 12.099 44.706 -4.143 1.00 54.73 C ATOM 1165 CG ARG A 153 11.592 46.145 -4.275 1.00 59.16 C ATOM 1166 CD ARG A 153 11.328 46.830 -2.955 1.00 60.86 C ATOM 1167 NE ARG A 153 12.556 46.909 -2.168 1.00 61.37 N ATOM 1168 CZ ARG A 153 12.607 47.057 -0.837 1.00 69.11 C ATOM 1169 NH1 ARG A 153 11.495 47.168 -0.100 1.00 73.57 N ATOM 1170 NH2 ARG A 153 13.794 47.093 -0.217 1.00 68.60 N ATOM 1171 N GLY A 154 12.799 41.643 -5.800 1.00 45.71 N ATOM 1172 CA GLY A 154 13.684 40.510 -5.939 1.00 41.22 C ATOM 1173 C GLY A 154 13.831 39.679 -4.695 1.00 38.27 C ATOM 1174 O GLY A 154 14.837 38.976 -4.532 1.00 34.74 O ATOM 1175 N PHE A 155 12.861 39.776 -3.790 1.00 38.53 N ATOM 1176 CA PHE A 155 12.880 38.912 -2.628 1.00 36.95 C ATOM 1177 C PHE A 155 11.513 38.607 -2.099 1.00 36.11 C ATOM 1178 O PHE A 155 10.559 39.303 -2.427 1.00 34.36 O ATOM 1179 CB PHE A 155 13.825 39.411 -1.525 1.00 37.16 C ATOM 1180 CG PHE A 155 13.531 40.796 -0.956 1.00 34.53 C ATOM 1181 CD1 PHE A 155 14.113 41.934 -1.504 1.00 35.66 C ATOM 1182 CD2 PHE A 155 12.788 40.951 0.199 1.00 34.57 C ATOM 1183 CE1 PHE A 155 13.885 43.203 -0.960 1.00 36.89 C ATOM 1184 CE2 PHE A 155 12.565 42.216 0.769 1.00 37.13 C ATOM 1185 CZ PHE A 155 13.137 43.347 0.209 1.00 38.76 C ATOM 1186 N GLY A 156 11.423 37.538 -1.304 1.00 34.57 N ATOM 1187 CA GLY A 156 10.171 37.230 -0.607 1.00 37.62 C ATOM 1188 C GLY A 156 10.330 36.563 0.749 1.00 36.73 C ATOM 1189 O GLY A 156 11.452 36.333 1.244 1.00 35.72 O ATOM 1190 N PHE A 157 9.198 36.279 1.366 1.00 34.95 N ATOM 1191 CA PHE A 157 9.144 35.587 2.677 1.00 32.42 C ATOM 1192 C PHE A 157 8.132 34.513 2.695 1.00 34.92 C ATOM 1193 O PHE A 157 6.970 34.698 2.177 1.00 37.96 O ATOM 1194 CB PHE A 157 8.823 36.550 3.796 1.00 33.76 C ATOM 1195 CG PHE A 157 9.743 37.691 3.869 1.00 35.31 C ATOM 1196 CD1 PHE A 157 10.922 37.605 4.639 1.00 39.10 C ATOM 1197 CD2 PHE A 157 9.470 38.871 3.181 1.00 38.53 C ATOM 1198 CE1 PHE A 157 11.804 38.672 4.705 1.00 38.73 C ATOM 1199 CE2 PHE A 157 10.353 39.938 3.241 1.00 39.28 C ATOM 1200 CZ PHE A 157 11.526 39.838 4.017 1.00 40.75 C ATOM 1201 N VAL A 158 8.560 33.369 3.234 1.00 33.92 N ATOM 1202 CA VAL A 158 7.726 32.200 3.420 1.00 32.06 C ATOM 1203 C VAL A 158 7.656 31.912 4.925 1.00 35.69 C ATOM 1204 O VAL A 158 8.682 31.764 5.554 1.00 27.67 O ATOM 1205 CB VAL A 158 8.306 30.984 2.735 1.00 33.44 C ATOM 1206 CG1 VAL A 158 7.394 29.772 2.897 1.00 36.14 C ATOM 1207 CG2 VAL A 158 8.577 31.235 1.261 1.00 36.62 C ATOM 1208 N THR A 159 6.450 31.822 5.482 1.00 33.80 N ATOM 1209 CA THR A 159 6.270 31.565 6.899 1.00 36.84 C ATOM 1210 C THR A 159 5.651 30.205 6.998 1.00 37.81 C ATOM 1211 O THR A 159 4.667 29.877 6.297 1.00 36.26 O ATOM 1212 CB THR A 159 5.397 32.638 7.560 1.00 37.32 C ATOM 1213 OG1 THR A 159 5.932 33.929 7.290 1.00 36.67 O ATOM 1214 CG2 THR A 159 5.348 32.517 9.068 1.00 34.43 C ATOM 1215 N PHE A 160 6.232 29.368 7.843 1.00 34.11 N ATOM 1216 CA PHE A 160 5.694 28.042 8.050 1.00 32.82 C ATOM 1217 C PHE A 160 4.912 28.004 9.364 1.00 31.28 C ATOM 1218 O PHE A 160 4.828 29.001 10.032 1.00 30.74 O ATOM 1219 CB PHE A 160 6.766 26.986 8.040 1.00 33.02 C ATOM 1220 CG PHE A 160 7.505 26.837 6.727 1.00 34.03 C ATOM 1221 CD1 PHE A 160 8.546 27.683 6.411 1.00 35.90 C ATOM 1222 CD2 PHE A 160 7.233 25.754 5.874 1.00 35.83 C ATOM 1223 CE1 PHE A 160 9.258 27.521 5.232 1.00 36.22 C ATOM 1224 CE2 PHE A 160 7.939 25.562 4.695 1.00 37.19 C ATOM 1225 CZ PHE A 160 8.971 26.435 4.368 1.00 38.33 C ATOM 1226 N ASP A 161 4.289 26.867 9.681 1.00 38.08 N ATOM 1227 CA ASP A 161 3.559 26.749 10.959 1.00 42.99 C ATOM 1228 C ASP A 161 4.485 26.276 12.076 1.00 38.70 C ATOM 1229 O ASP A 161 4.051 26.174 13.213 1.00 34.45 O ATOM 1230 CB ASP A 161 2.313 25.853 10.840 1.00 43.56 C ATOM 1231 CG ASP A 161 2.638 24.355 10.799 1.00 54.97 C ATOM 1232 OD1 ASP A 161 3.817 23.953 10.631 1.00 49.29 O ATOM 1233 OD2 ASP A 161 1.670 23.563 10.930 1.00 57.14 O ATOM 1234 N ASP A 162 5.776 26.074 11.761 1.00 37.80 N ATOM 1235 CA ASP A 162 6.754 25.463 12.677 1.00 36.07 C ATOM 1236 C ASP A 162 8.150 25.957 12.248 1.00 37.03 C ATOM 1237 O ASP A 162 8.377 26.264 11.093 1.00 35.60 O ATOM 1238 CB ASP A 162 6.666 23.933 12.543 1.00 42.63 C ATOM 1239 CG ASP A 162 7.677 23.172 13.431 1.00 45.19 C ATOM 1240 OD1 ASP A 162 8.119 23.690 14.468 1.00 47.17 O ATOM 1241 OD2 ASP A 162 8.026 22.044 13.043 1.00 49.27 O ATOM 1242 N HIS A 163 9.059 26.039 13.199 1.00 31.78 N ATOM 1243 CA HIS A 163 10.374 26.572 12.952 1.00 34.65 C ATOM 1244 C HIS A 163 11.262 25.565 12.276 1.00 31.24 C ATOM 1245 O HIS A 163 12.247 25.953 11.673 1.00 36.87 O ATOM 1246 CB HIS A 163 11.011 27.011 14.251 1.00 37.16 C ATOM 1247 CG HIS A 163 11.332 25.845 15.133 1.00 40.69 C ATOM 1248 ND1 HIS A 163 12.532 25.173 15.048 1.00 37.05 N ATOM 1249 CD2 HIS A 163 10.592 25.197 16.064 1.00 37.95 C ATOM 1250 CE1 HIS A 163 12.506 24.133 15.865 1.00 40.11 C ATOM 1251 NE2 HIS A 163 11.347 24.138 16.504 1.00 43.41 N ATOM 1252 N ASP A 164 10.972 24.271 12.405 1.00 30.58 N ATOM 1253 CA ASP A 164 11.859 23.260 11.911 1.00 28.88 C ATOM 1254 C ASP A 164 12.129 23.247 10.409 1.00 28.11 C ATOM 1255 O ASP A 164 13.278 23.024 9.982 1.00 32.78 O ATOM 1256 CB ASP A 164 11.434 21.858 12.372 1.00 30.34 C ATOM 1257 CG ASP A 164 12.501 20.816 12.042 1.00 27.42 C ATOM 1258 OD1 ASP A 164 13.687 20.960 12.462 1.00 31.03 O ATOM 1259 OD2 ASP A 164 12.213 19.861 11.352 1.00 31.24 O ATOM 1260 N PRO A 165 11.083 23.456 9.584 1.00 32.39 N ATOM 1261 CA PRO A 165 11.312 23.650 8.166 1.00 33.26 C ATOM 1262 C PRO A 165 12.333 24.711 7.869 1.00 30.65 C ATOM 1263 O PRO A 165 13.244 24.463 7.082 1.00 32.81 O ATOM 1264 CB PRO A 165 9.918 24.107 7.652 1.00 32.42 C ATOM 1265 CG PRO A 165 8.985 23.314 8.535 1.00 32.47 C ATOM 1266 CD PRO A 165 9.631 23.441 9.887 1.00 31.31 C ATOM 1267 N VAL A 166 12.189 25.868 8.520 1.00 28.03 N ATOM 1268 CA VAL A 166 13.108 26.950 8.343 1.00 29.45 C ATOM 1269 C VAL A 166 14.561 26.503 8.692 1.00 30.62 C ATOM 1270 O VAL A 166 15.495 26.774 7.920 1.00 23.78 O ATOM 1271 CB VAL A 166 12.635 28.195 9.124 1.00 34.12 C ATOM 1272 CG1 VAL A 166 13.668 29.307 9.068 1.00 35.37 C ATOM 1273 CG2 VAL A 166 11.276 28.704 8.592 1.00 36.69 C ATOM 1274 N ASP A 167 14.720 25.764 9.801 1.00 27.42 N ATOM 1275 CA ASP A 167 16.031 25.292 10.204 1.00 29.70 C ATOM 1276 C ASP A 167 16.607 24.339 9.158 1.00 29.43 C ATOM 1277 O ASP A 167 17.781 24.429 8.818 1.00 30.36 O ATOM 1278 CB ASP A 167 15.977 24.637 11.573 1.00 27.75 C ATOM 1279 CG ASP A 167 15.667 25.642 12.667 1.00 28.77 C ATOM 1280 OD1 ASP A 167 15.908 26.879 12.507 1.00 31.36 O ATOM 1281 OD2 ASP A 167 15.107 25.204 13.663 1.00 31.60 O ATOM 1282 N LYS A 168 15.783 23.463 8.626 1.00 30.56 N ATOM 1283 CA LYS A 168 16.286 22.503 7.677 1.00 32.22 C ATOM 1284 C LYS A 168 16.714 23.251 6.378 1.00 32.45 C ATOM 1285 O LYS A 168 17.839 23.119 5.842 1.00 29.59 O ATOM 1286 CB LYS A 168 15.206 21.416 7.465 1.00 31.22 C ATOM 1287 CG LYS A 168 15.617 20.337 6.478 1.00 32.65 C ATOM 1288 CD LYS A 168 14.690 19.137 6.476 1.00 35.16 C ATOM 1289 CE LYS A 168 14.718 18.430 5.133 1.00 41.44 C ATOM 1290 NZ LYS A 168 14.155 17.053 5.282 1.00 43.79 N ATOM 1291 N ILE A 169 15.829 24.131 5.942 1.00 31.79 N ATOM 1292 CA ILE A 169 16.047 24.871 4.712 1.00 30.36 C ATOM 1293 C ILE A 169 17.361 25.639 4.760 1.00 32.13 C ATOM 1294 O ILE A 169 18.142 25.527 3.847 1.00 31.19 O ATOM 1295 CB ILE A 169 14.876 25.763 4.436 1.00 33.12 C ATOM 1296 CG1 ILE A 169 13.681 24.865 4.091 1.00 30.25 C ATOM 1297 CG2 ILE A 169 15.188 26.685 3.236 1.00 34.84 C ATOM 1298 CD1 ILE A 169 12.299 25.521 4.192 1.00 31.78 C ATOM 1299 N VAL A 170 17.616 26.348 5.849 1.00 28.59 N ATOM 1300 CA VAL A 170 18.747 27.214 5.931 1.00 32.34 C ATOM 1301 C VAL A 170 19.994 26.369 6.066 1.00 32.45 C ATOM 1302 O VAL A 170 21.009 26.697 5.504 1.00 33.87 O ATOM 1303 CB VAL A 170 18.733 28.274 7.092 1.00 36.56 C ATOM 1304 CG1 VAL A 170 17.566 29.243 7.001 1.00 40.24 C ATOM 1305 CG2 VAL A 170 18.706 27.614 8.429 1.00 43.23 C ATOM 1306 N LEU A 171 19.903 25.265 6.801 1.00 31.76 N ATOM 1307 CA LEU A 171 21.023 24.374 6.912 1.00 33.60 C ATOM 1308 C LEU A 171 21.407 23.726 5.593 1.00 30.71 C ATOM 1309 O LEU A 171 22.559 23.514 5.333 1.00 28.78 O ATOM 1310 CB LEU A 171 20.744 23.348 8.008 1.00 35.10 C ATOM 1311 CG LEU A 171 20.884 24.022 9.380 1.00 34.45 C ATOM 1312 CD1 LEU A 171 20.203 23.198 10.463 1.00 42.08 C ATOM 1313 CD2 LEU A 171 22.356 24.190 9.763 1.00 39.47 C ATOM 1314 N GLN A 172 20.442 23.501 4.726 1.00 28.22 N ATOM 1315 CA GLN A 172 20.736 22.994 3.387 1.00 31.72 C ATOM 1316 C GLN A 172 21.501 23.996 2.504 1.00 36.04 C ATOM 1317 O GLN A 172 22.175 23.593 1.540 1.00 31.87 O ATOM 1318 CB GLN A 172 19.448 22.612 2.685 1.00 29.15 C ATOM 1319 CG GLN A 172 18.812 21.357 3.202 1.00 30.48 C ATOM 1320 CD GLN A 172 17.580 21.007 2.343 1.00 30.55 C ATOM 1321 OE1 GLN A 172 17.041 21.847 1.658 1.00 34.03 O ATOM 1322 NE2 GLN A 172 17.176 19.762 2.372 1.00 32.89 N ATOM 1323 N LYS A 173 21.312 25.290 2.801 1.00 30.06 N ATOM 1324 CA LYS A 173 22.113 26.337 2.284 1.00 32.50 C ATOM 1325 C LYS A 173 21.877 26.720 0.840 1.00 31.78 C ATOM 1326 O LYS A 173 21.647 27.847 0.570 1.00 33.32 O ATOM 1327 CB LYS A 173 23.601 26.071 2.538 1.00 43.07 C ATOM 1328 CG LYS A 173 24.416 27.338 2.477 1.00 48.14 C ATOM 1329 CD LYS A 173 25.890 27.119 2.787 1.00 51.46 C ATOM 1330 CE LYS A 173 26.659 28.381 2.439 1.00 55.23 C ATOM 1331 NZ LYS A 173 27.987 28.424 3.104 1.00 60.97 N ATOM 1332 N TYR A 174 21.978 25.792 -0.089 1.00 35.13 N ATOM 1333 CA TYR A 174 21.957 26.130 -1.515 1.00 37.70 C ATOM 1334 C TYR A 174 20.611 25.776 -2.029 1.00 38.33 C ATOM 1335 O TYR A 174 20.116 24.698 -1.753 1.00 35.21 O ATOM 1336 CB TYR A 174 23.012 25.333 -2.229 1.00 37.44 C ATOM 1337 CG TYR A 174 24.375 25.577 -1.639 1.00 36.43 C ATOM 1338 CD1 TYR A 174 24.924 26.845 -1.685 1.00 40.37 C ATOM 1339 CD2 TYR A 174 25.101 24.547 -1.005 1.00 40.75 C ATOM 1340 CE1 TYR A 174 26.159 27.110 -1.137 1.00 42.59 C ATOM 1341 CE2 TYR A 174 26.359 24.792 -0.435 1.00 39.09 C ATOM 1342 CZ TYR A 174 26.864 26.089 -0.517 1.00 40.57 C ATOM 1343 OH TYR A 174 28.085 26.424 -0.041 1.00 46.81 O ATOM 1344 N HIS A 175 19.993 26.700 -2.740 1.00 33.13 N ATOM 1345 CA HIS A 175 18.692 26.471 -3.303 1.00 34.22 C ATOM 1346 C HIS A 175 18.593 27.228 -4.617 1.00 35.61 C ATOM 1347 O HIS A 175 18.972 28.419 -4.700 1.00 31.65 O ATOM 1348 CB HIS A 175 17.611 27.021 -2.394 1.00 33.64 C ATOM 1349 CG HIS A 175 17.612 26.396 -1.044 1.00 33.11 C ATOM 1350 ND1 HIS A 175 17.094 25.153 -0.808 1.00 35.43 N ATOM 1351 CD2 HIS A 175 18.149 26.811 0.121 1.00 32.02 C ATOM 1352 CE1 HIS A 175 17.252 24.849 0.469 1.00 34.38 C ATOM 1353 NE2 HIS A 175 17.874 25.848 1.061 1.00 32.53 N ATOM 1354 N THR A 176 18.034 26.531 -5.594 1.00 31.54 N ATOM 1355 CA THR A 176 17.752 27.097 -6.868 1.00 35.19 C ATOM 1356 C THR A 176 16.255 27.171 -7.034 1.00 33.09 C ATOM 1357 O THR A 176 15.552 26.185 -6.859 1.00 38.70 O ATOM 1358 CB THR A 176 18.343 26.234 -7.957 1.00 39.03 C ATOM 1359 OG1 THR A 176 19.772 26.216 -7.825 1.00 39.34 O ATOM 1360 CG2 THR A 176 17.903 26.759 -9.305 1.00 41.81 C ATOM 1361 N ILE A 177 15.766 28.354 -7.348 1.00 34.57 N ATOM 1362 CA ILE A 177 14.351 28.582 -7.336 1.00 35.21 C ATOM 1363 C ILE A 177 14.020 29.409 -8.559 1.00 39.67 C ATOM 1364 O ILE A 177 14.443 30.585 -8.665 1.00 34.64 O ATOM 1365 CB ILE A 177 13.950 29.342 -6.052 1.00 33.50 C ATOM 1366 CG1 ILE A 177 14.407 28.576 -4.775 1.00 32.68 C ATOM 1367 CG2 ILE A 177 12.471 29.672 -6.049 1.00 35.26 C ATOM 1368 CD1 ILE A 177 14.175 29.384 -3.504 1.00 33.31 C ATOM 1369 N ASN A 178 13.222 28.826 -9.460 1.00 42.19 N ATOM 1370 CA ASN A 178 12.846 29.457 -10.723 1.00 41.64 C ATOM 1371 C ASN A 178 14.059 29.878 -11.523 1.00 41.76 C ATOM 1372 O ASN A 178 14.134 31.037 -11.981 1.00 43.98 O ATOM 1373 CB ASN A 178 11.910 30.664 -10.529 1.00 45.59 C ATOM 1374 CG ASN A 178 11.373 31.182 -11.861 1.00 48.90 C ATOM 1375 OD1 ASN A 178 11.147 30.379 -12.755 1.00 43.09 O ATOM 1376 ND2 ASN A 178 11.186 32.508 -12.003 1.00 47.86 N ATOM 1377 N GLY A 179 14.992 28.936 -11.661 1.00 38.87 N ATOM 1378 CA GLY A 179 16.262 29.135 -12.344 1.00 44.95 C ATOM 1379 C GLY A 179 17.283 30.030 -11.646 1.00 41.52 C ATOM 1380 O GLY A 179 18.336 30.269 -12.220 1.00 46.28 O ATOM 1381 N HIS A 180 17.002 30.511 -10.429 1.00 41.89 N ATOM 1382 CA HIS A 180 17.912 31.441 -9.731 1.00 40.47 C ATOM 1383 C HIS A 180 18.579 30.768 -8.539 1.00 38.86 C ATOM 1384 O HIS A 180 17.934 30.074 -7.767 1.00 33.63 O ATOM 1385 CB HIS A 180 17.136 32.659 -9.226 1.00 40.74 C ATOM 1386 CG HIS A 180 16.391 33.414 -10.291 1.00 47.00 C ATOM 1387 ND1 HIS A 180 17.022 34.093 -11.318 1.00 48.03 N ATOM 1388 CD2 HIS A 180 15.066 33.639 -10.457 1.00 51.45 C ATOM 1389 CE1 HIS A 180 16.118 34.684 -12.078 1.00 49.55 C ATOM 1390 NE2 HIS A 180 14.921 34.430 -11.574 1.00 52.07 N ATOM 1391 N ASN A 181 19.858 31.026 -8.358 1.00 36.26 N ATOM 1392 CA ASN A 181 20.537 30.671 -7.102 1.00 36.30 C ATOM 1393 C ASN A 181 20.130 31.636 -5.994 1.00 38.18 C ATOM 1394 O ASN A 181 20.554 32.778 -5.975 1.00 34.86 O ATOM 1395 CB ASN A 181 22.049 30.681 -7.280 1.00 40.56 C ATOM 1396 CG ASN A 181 22.528 29.562 -8.205 1.00 42.55 C ATOM 1397 OD1 ASN A 181 23.738 29.379 -8.409 1.00 57.07 O ATOM 1398 ND2 ASN A 181 21.586 28.804 -8.764 1.00 37.25 N ATOM 1399 N ALA A 182 19.232 31.192 -5.119 1.00 35.41 N ATOM 1400 CA ALA A 182 18.564 32.095 -4.194 1.00 34.16 C ATOM 1401 C ALA A 182 19.355 32.171 -2.894 1.00 32.04 C ATOM 1402 O ALA A 182 20.179 31.331 -2.613 1.00 32.35 O ATOM 1403 CB ALA A 182 17.123 31.658 -3.936 1.00 32.23 C ATOM 1404 N GLU A 183 19.115 33.209 -2.100 1.00 34.78 N ATOM 1405 CA GLU A 183 19.753 33.312 -0.826 1.00 36.73 C ATOM 1406 C GLU A 183 18.677 33.070 0.170 1.00 32.61 C ATOM 1407 O GLU A 183 17.861 33.932 0.348 1.00 30.66 O ATOM 1408 CB GLU A 183 20.342 34.714 -0.636 1.00 43.56 C ATOM 1409 CG GLU A 183 21.553 34.694 0.282 1.00 57.79 C ATOM 1410 CD GLU A 183 22.710 33.818 -0.243 1.00 69.78 C ATOM 1411 OE1 GLU A 183 23.521 33.382 0.606 1.00 77.88 O ATOM 1412 OE2 GLU A 183 22.792 33.534 -1.482 1.00 65.66 O ATOM 1413 N VAL A 184 18.678 31.935 0.856 1.00 31.49 N ATOM 1414 CA VAL A 184 17.569 31.667 1.742 1.00 36.24 C ATOM 1415 C VAL A 184 18.095 31.752 3.163 1.00 35.63 C ATOM 1416 O VAL A 184 19.097 31.150 3.449 1.00 36.32 O ATOM 1417 CB VAL A 184 16.876 30.338 1.423 1.00 37.74 C ATOM 1418 CG1 VAL A 184 16.656 30.172 -0.084 1.00 33.06 C ATOM 1419 CG2 VAL A 184 17.658 29.172 2.002 1.00 46.68 C ATOM 1420 N ARG A 185 17.445 32.544 4.021 1.00 32.90 N ATOM 1421 CA ARG A 185 17.884 32.698 5.419 1.00 33.41 C ATOM 1422 C ARG A 185 16.701 32.839 6.313 1.00 32.62 C ATOM 1423 O ARG A 185 15.577 33.009 5.830 1.00 29.65 O ATOM 1424 CB ARG A 185 18.739 33.955 5.564 1.00 38.10 C ATOM 1425 CG ARG A 185 20.204 33.604 5.802 1.00 50.97 C ATOM 1426 CD ARG A 185 21.149 34.081 4.745 1.00 52.19 C ATOM 1427 NE ARG A 185 21.124 35.536 4.733 1.00 61.52 N ATOM 1428 CZ ARG A 185 21.795 36.291 3.882 1.00 58.29 C ATOM 1429 NH1 ARG A 185 21.676 37.601 3.956 1.00 58.20 N ATOM 1430 NH2 ARG A 185 22.585 35.732 2.969 1.00 55.12 N ATOM 1431 N ALYS A 186 16.943 32.796 7.618 0.50 28.45 N ATOM 1432 N BLYS A 186 16.939 32.774 7.619 0.50 31.19 N ATOM 1433 CA ALYS A 186 15.909 33.203 8.564 0.50 29.84 C ATOM 1434 CA BLYS A 186 15.910 33.139 8.598 0.50 34.52 C ATOM 1435 C ALYS A 186 15.585 34.671 8.314 0.50 32.47 C ATOM 1436 C BLYS A 186 15.606 34.649 8.437 0.50 35.14 C ATOM 1437 O ALYS A 186 16.451 35.463 7.881 0.50 30.20 O ATOM 1438 O BLYS A 186 16.523 35.451 8.169 0.50 33.11 O ATOM 1439 CB ALYS A 186 16.340 33.067 10.009 0.50 27.63 C ATOM 1440 CB BLYS A 186 16.357 32.813 10.032 0.50 35.68 C ATOM 1441 CG ALYS A 186 16.515 31.671 10.526 0.50 24.29 C ATOM 1442 CG BLYS A 186 16.466 31.337 10.375 0.50 36.26 C ATOM 1443 CD ALYS A 186 17.109 31.771 11.920 0.50 23.12 C ATOM 1444 CD BLYS A 186 17.436 31.088 11.534 0.50 39.23 C ATOM 1445 CE ALYS A 186 17.690 30.449 12.398 0.50 22.88 C ATOM 1446 CE BLYS A 186 17.162 29.778 12.266 0.50 40.62 C ATOM 1447 NZ ALYS A 186 18.531 30.689 13.607 0.50 22.85 N ATOM 1448 NZ BLYS A 186 18.251 29.268 13.164 0.50 43.03 N ATOM 1449 N ALA A 187 14.318 35.009 8.552 1.00 32.38 N ATOM 1450 CA ALA A 187 13.849 36.376 8.453 1.00 32.63 C ATOM 1451 C ALA A 187 13.755 36.835 9.893 1.00 35.08 C ATOM 1452 O ALA A 187 12.771 36.542 10.597 1.00 33.66 O ATOM 1453 CB ALA A 187 12.482 36.411 7.731 1.00 32.82 C ATOM 1454 N LEU A 188 14.848 37.458 10.358 1.00 33.68 N ATOM 1455 CA LEU A 188 14.943 37.932 11.720 1.00 36.66 C ATOM 1456 C LEU A 188 14.577 39.403 11.884 1.00 34.27 C ATOM 1457 O LEU A 188 14.956 40.214 11.057 1.00 35.76 O ATOM 1458 CB LEU A 188 16.393 37.682 12.224 1.00 34.51 C ATOM 1459 CG LEU A 188 16.681 36.181 12.301 1.00 34.00 C ATOM 1460 CD1 LEU A 188 18.046 35.892 12.868 1.00 39.45 C ATOM 1461 CD2 LEU A 188 15.637 35.453 13.137 1.00 37.29 C ATOM 1462 N SER A 189 13.888 39.748 12.978 1.00 40.12 N ATOM 1463 CA SER A 189 13.636 41.164 13.346 1.00 44.97 C ATOM 1464 C SER A 189 14.934 41.848 13.850 1.00 47.20 C ATOM 1465 O SER A 189 15.946 41.183 14.055 1.00 42.25 O ATOM 1466 CB SER A 189 12.503 41.238 14.382 1.00 42.47 C ATOM 1467 OG SER A 189 13.018 40.852 15.638 1.00 45.73 O ATOM 1468 N ARG A 190 14.937 43.176 14.054 1.00 54.76 N ATOM 1469 CA ARG A 190 16.157 43.842 14.566 1.00 52.58 C ATOM 1470 C ARG A 190 16.461 43.329 15.970 1.00 48.32 C ATOM 1471 O ARG A 190 17.610 43.010 16.277 1.00 46.35 O ATOM 1472 CB ARG A 190 16.069 45.392 14.550 1.00 59.41 C ATOM 1473 CG ARG A 190 17.441 46.124 14.636 1.00 64.05 C ATOM 1474 CD ARG A 190 17.371 47.625 15.021 1.00 65.36 C ATOM 1475 NE ARG A 190 16.389 48.342 14.195 1.00 66.16 N ATOM 1476 CZ ARG A 190 15.165 48.750 14.566 1.00 67.68 C ATOM 1477 NH1 ARG A 190 14.716 48.604 15.811 1.00 73.16 N ATOM 1478 NH2 ARG A 190 14.369 49.346 13.673 1.00 65.77 N ATOM 1479 N GLN A 191 15.429 43.229 16.811 1.00 53.03 N ATOM 1480 CA GLN A 191 15.576 42.580 18.135 1.00 59.99 C ATOM 1481 C GLN A 191 16.260 41.217 18.046 1.00 50.50 C ATOM 1482 O GLN A 191 17.306 40.967 18.687 1.00 47.70 O ATOM 1483 CB GLN A 191 14.235 42.380 18.819 1.00 65.06 C ATOM 1484 CG GLN A 191 13.640 43.681 19.305 1.00 73.01 C ATOM 1485 CD GLN A 191 12.220 43.832 18.830 1.00 81.03 C ATOM 1486 OE1 GLN A 191 11.948 43.897 17.619 1.00 78.06 O ATOM 1487 NE2 GLN A 191 11.298 43.861 19.775 1.00 88.23 N ATOM 1488 N GLU A 192 15.684 40.363 17.210 1.00 43.46 N ATOM 1489 CA GLU A 192 16.183 39.012 17.050 1.00 41.41 C ATOM 1490 C GLU A 192 17.659 39.027 16.609 1.00 40.46 C ATOM 1491 O GLU A 192 18.485 38.238 17.140 1.00 38.76 O ATOM 1492 CB GLU A 192 15.252 38.234 16.125 1.00 42.24 C ATOM 1493 CG GLU A 192 13.913 37.945 16.786 1.00 43.34 C ATOM 1494 CD GLU A 192 12.885 37.386 15.848 1.00 44.48 C ATOM 1495 OE1 GLU A 192 13.050 37.458 14.608 1.00 42.53 O ATOM 1496 OE2 GLU A 192 11.881 36.858 16.362 1.00 45.04 O ATOM 1497 N MET A 193 18.018 39.986 15.751 1.00 40.79 N ATOM 1498 CA MET A 193 19.387 40.121 15.304 1.00 45.59 C ATOM 1499 C MET A 193 20.358 40.445 16.429 1.00 46.41 C ATOM 1500 O MET A 193 21.555 40.189 16.290 1.00 50.90 O ATOM 1501 CB MET A 193 19.508 41.165 14.181 1.00 49.79 C ATOM 1502 CG MET A 193 18.995 40.724 12.814 1.00 53.38 C ATOM 1503 SD MET A 193 19.761 39.214 12.162 1.00 58.09 S ATOM 1504 CE MET A 193 21.409 39.803 11.694 1.00 57.99 C ATOM 1505 N GLN A 194 19.884 40.979 17.543 1.00 48.87 N ATOM 1506 CA GLN A 194 20.764 41.169 18.703 1.00 54.22 C ATOM 1507 C GLN A 194 21.076 39.882 19.514 1.00 55.75 C ATOM 1508 O GLN A 194 21.886 39.949 20.448 1.00 61.88 O ATOM 1509 CB GLN A 194 20.194 42.240 19.631 1.00 59.60 C ATOM 1510 CG GLN A 194 19.904 43.588 18.975 1.00 59.54 C ATOM 1511 CD GLN A 194 19.826 44.689 20.021 1.00 72.65 C ATOM 1512 OE1 GLN A 194 19.162 44.540 21.057 1.00 81.12 O ATOM 1513 NE2 GLN A 194 20.528 45.790 19.778 1.00 74.19 N ATOM 1514 N GLU A 195 20.463 38.730 19.190 1.00 59.57 N ATOM 1515 CA GLU A 195 20.779 37.437 19.886 1.00 65.64 C ATOM 1516 C GLU A 195 22.039 36.732 19.354 1.00 60.59 C ATOM 1517 O GLU A 195 22.297 36.745 18.155 1.00 52.61 O ATOM 1518 CB GLU A 195 19.607 36.435 19.835 1.00 68.83 C ATOM 1519 CG GLU A 195 18.780 36.348 21.107 1.00 66.46 C ATOM 1520 CD GLU A 195 17.695 37.385 21.142 1.00 69.64 C ATOM 1521 OE1 GLU A 195 16.600 37.046 21.591 1.00 70.68 O ATOM 1522 OE2 GLU A 195 17.919 38.522 20.693 1.00 72.52 O TER 1523 GLU A 195 ATOM 1524 O5' A B 1 20.246 30.336 28.167 1.00 52.01 O ATOM 1525 C5' A B 1 21.007 30.028 29.337 1.00 51.31 C ATOM 1526 C4' A B 1 21.413 28.576 29.310 1.00 50.41 C ATOM 1527 O4' A B 1 20.238 27.713 29.393 1.00 44.04 O ATOM 1528 C3' A B 1 22.134 28.055 28.060 1.00 50.60 C ATOM 1529 O3' A B 1 23.537 28.403 28.014 1.00 62.35 O ATOM 1530 C2' A B 1 21.971 26.544 28.243 1.00 43.45 C ATOM 1531 O2' A B 1 22.901 26.140 29.236 1.00 40.41 O ATOM 1532 C1' A B 1 20.583 26.429 28.889 1.00 46.12 C ATOM 1533 N9 A B 1 19.476 25.929 28.061 1.00 43.37 N ATOM 1534 C8 A B 1 18.537 25.018 28.488 1.00 44.31 C ATOM 1535 N7 A B 1 17.597 24.774 27.609 1.00 44.61 N ATOM 1536 C5 A B 1 17.925 25.592 26.535 1.00 43.56 C ATOM 1537 C6 A B 1 17.333 25.774 25.270 1.00 42.98 C ATOM 1538 N6 A B 1 16.223 25.146 24.883 1.00 36.82 N ATOM 1539 N1 A B 1 17.919 26.646 24.416 1.00 37.26 N ATOM 1540 C2 A B 1 19.032 27.280 24.815 1.00 35.23 C ATOM 1541 N3 A B 1 19.690 27.185 25.976 1.00 39.27 N ATOM 1542 C4 A B 1 19.074 26.318 26.803 1.00 42.04 C ATOM 1543 P A B 2 24.274 28.993 26.650 1.00 66.45 P ATOM 1544 OP1 A B 2 25.745 28.909 26.868 1.00 80.25 O ATOM 1545 OP2 A B 2 23.651 30.292 26.279 1.00 76.51 O ATOM 1546 O5' A B 2 23.844 28.016 25.463 1.00 62.41 O ATOM 1547 C5' A B 2 24.212 26.630 25.486 1.00 48.94 C ATOM 1548 C4' A B 2 25.207 26.283 24.399 1.00 41.43 C ATOM 1549 O4' A B 2 24.529 25.562 23.348 1.00 35.61 O ATOM 1550 C3' A B 2 25.980 27.413 23.709 1.00 35.90 C ATOM 1551 O3' A B 2 27.206 26.925 23.198 1.00 32.04 O ATOM 1552 C2' A B 2 25.200 27.636 22.434 1.00 33.83 C ATOM 1553 O2' A B 2 25.896 27.852 21.234 1.00 36.20 O ATOM 1554 C1' A B 2 24.729 26.230 22.126 1.00 34.19 C ATOM 1555 N9 A B 2 23.465 26.276 21.421 1.00 32.58 N ATOM 1556 C8 A B 2 22.281 26.898 21.722 1.00 31.83 C ATOM 1557 N7 A B 2 21.336 26.681 20.845 1.00 32.68 N ATOM 1558 C5 A B 2 21.932 25.837 19.923 1.00 32.29 C ATOM 1559 C6 A B 2 21.469 25.260 18.743 1.00 35.97 C ATOM 1560 N6 A B 2 20.222 25.422 18.274 1.00 30.92 N ATOM 1561 N1 A B 2 22.324 24.475 18.056 1.00 35.73 N ATOM 1562 C2 A B 2 23.566 24.308 18.525 1.00 37.00 C ATOM 1563 N3 A B 2 24.125 24.821 19.609 1.00 31.75 N ATOM 1564 C4 A B 2 23.238 25.569 20.278 1.00 31.44 C ATOM 1565 P G B 3 28.417 26.671 24.129 1.00 33.04 P ATOM 1566 OP1 G B 3 28.270 27.498 25.336 1.00 41.13 O ATOM 1567 OP2 G B 3 29.655 26.709 23.287 1.00 32.13 O ATOM 1568 O5' G B 3 28.262 25.150 24.566 1.00 31.78 O ATOM 1569 C5' G B 3 28.045 24.145 23.549 1.00 31.96 C ATOM 1570 C4' G B 3 28.949 22.987 23.810 1.00 30.66 C ATOM 1571 O4' G B 3 28.506 21.872 23.003 1.00 31.54 O ATOM 1572 C3' G B 3 30.433 23.150 23.478 1.00 31.69 C ATOM 1573 O3' G B 3 31.124 22.258 24.377 1.00 33.86 O ATOM 1574 C2' G B 3 30.440 22.725 22.023 1.00 31.95 C ATOM 1575 O2' G B 3 31.587 22.237 21.380 1.00 29.29 O ATOM 1576 C1' G B 3 29.517 21.522 22.094 1.00 28.82 C ATOM 1577 N9 G B 3 28.894 21.123 20.847 1.00 29.29 N ATOM 1578 C8 G B 3 28.774 19.835 20.388 1.00 28.87 C ATOM 1579 N7 G B 3 28.150 19.755 19.246 1.00 30.71 N ATOM 1580 C5 G B 3 27.882 21.074 18.907 1.00 29.52 C ATOM 1581 C6 G B 3 27.168 21.604 17.808 1.00 27.25 C ATOM 1582 O6 G B 3 26.696 21.008 16.842 1.00 26.37 O ATOM 1583 N1 G B 3 27.092 22.989 17.867 1.00 27.59 N ATOM 1584 C2 G B 3 27.537 23.760 18.909 1.00 29.95 C ATOM 1585 N2 G B 3 27.351 25.078 18.782 1.00 28.73 N ATOM 1586 N3 G B 3 28.172 23.274 19.968 1.00 32.91 N ATOM 1587 C4 G B 3 28.310 21.930 19.898 1.00 28.87 C ATOM 1588 P G B 4 32.647 22.586 24.909 1.00 37.49 P ATOM 1589 OP1 G B 4 32.524 23.591 25.963 1.00 38.57 O ATOM 1590 OP2 G B 4 33.480 22.772 23.739 1.00 33.74 O ATOM 1591 O5' G B 4 33.098 21.234 25.618 1.00 34.27 O ATOM 1592 C5' G B 4 32.346 20.671 26.698 1.00 35.47 C ATOM 1593 C4' G B 4 32.765 19.239 26.916 1.00 38.08 C ATOM 1594 O4' G B 4 32.018 18.370 26.010 1.00 37.49 O ATOM 1595 C3' G B 4 34.246 18.954 26.645 1.00 37.65 C ATOM 1596 O3' G B 4 34.702 17.932 27.512 1.00 41.57 O ATOM 1597 C2' G B 4 34.237 18.501 25.184 1.00 35.16 C ATOM 1598 O2' G B 4 35.325 17.711 24.829 1.00 35.54 O ATOM 1599 C1' G B 4 32.911 17.731 25.101 1.00 34.64 C ATOM 1600 N9 G B 4 32.308 17.770 23.767 1.00 36.57 N ATOM 1601 C8 G B 4 32.327 18.825 22.885 1.00 33.95 C ATOM 1602 N7 G B 4 31.701 18.571 21.769 1.00 36.02 N ATOM 1603 C5 G B 4 31.253 17.265 21.914 1.00 33.59 C ATOM 1604 C6 G B 4 30.481 16.455 21.037 1.00 28.20 C ATOM 1605 O6 G B 4 30.109 16.705 19.891 1.00 25.39 O ATOM 1606 N1 G B 4 30.254 15.196 21.576 1.00 28.40 N ATOM 1607 C2 G B 4 30.676 14.782 22.821 1.00 33.01 C ATOM 1608 N2 G B 4 30.333 13.540 23.182 1.00 42.03 N ATOM 1609 N3 G B 4 31.371 15.533 23.653 1.00 29.40 N ATOM 1610 C4 G B 4 31.618 16.756 23.143 1.00 32.05 C ATOM 1611 P A B 5 35.522 18.301 28.882 1.00 37.97 P ATOM 1612 OP1 A B 5 35.805 17.032 29.573 1.00 44.39 O ATOM 1613 OP2 A B 5 34.791 19.340 29.565 1.00 43.90 O ATOM 1614 O5' A B 5 36.806 19.043 28.322 1.00 38.16 O ATOM 1615 C5' A B 5 37.818 18.231 27.768 1.00 42.98 C ATOM 1616 C4' A B 5 38.870 19.082 27.142 1.00 40.76 C ATOM 1617 O4' A B 5 39.957 18.203 26.769 1.00 40.38 O ATOM 1618 C3' A B 5 38.436 19.798 25.861 1.00 45.80 C ATOM 1619 O3' A B 5 39.115 21.037 25.654 1.00 47.91 O ATOM 1620 C2' A B 5 38.867 18.822 24.766 1.00 46.62 C ATOM 1621 O2' A B 5 39.165 19.358 23.479 1.00 50.29 O ATOM 1622 C1' A B 5 40.144 18.240 25.374 1.00 43.07 C ATOM 1623 N9 A B 5 40.486 16.892 24.932 1.00 43.81 N ATOM 1624 C8 A B 5 41.691 16.429 24.452 1.00 44.76 C ATOM 1625 N7 A B 5 41.673 15.163 24.114 1.00 41.69 N ATOM 1626 C5 A B 5 40.367 14.769 24.377 1.00 42.80 C ATOM 1627 C6 A B 5 39.707 13.535 24.249 1.00 45.39 C ATOM 1628 N6 A B 5 40.297 12.428 23.798 1.00 45.64 N ATOM 1629 N1 A B 5 38.402 13.476 24.611 1.00 48.02 N ATOM 1630 C2 A B 5 37.810 14.588 25.071 1.00 40.85 C ATOM 1631 N3 A B 5 38.322 15.806 25.225 1.00 39.99 N ATOM 1632 C4 A B 5 39.628 15.821 24.887 1.00 42.31 C ATOM 1633 P C B 6 38.681 22.381 26.431 1.00 54.57 P ATOM 1634 OP1 C B 6 37.194 22.335 26.730 1.00 55.68 O ATOM 1635 OP2 C B 6 39.284 23.526 25.713 1.00 50.16 O ATOM 1636 O5' C B 6 39.334 22.201 27.871 1.00 47.02 O ATOM 1637 C5' C B 6 40.702 22.481 28.211 1.00 50.49 C ATOM 1638 C4' C B 6 40.735 22.578 29.711 1.00 56.79 C ATOM 1639 O4' C B 6 40.141 23.849 30.104 1.00 57.36 O ATOM 1640 C3' C B 6 39.902 21.502 30.433 1.00 58.39 C ATOM 1641 O3' C B 6 40.511 21.034 31.626 1.00 60.05 O ATOM 1642 C2' C B 6 38.614 22.232 30.804 1.00 58.42 C ATOM 1643 O2' C B 6 37.783 21.913 31.913 1.00 56.03 O ATOM 1644 C1' C B 6 39.181 23.601 31.118 1.00 63.88 C ATOM 1645 N1 C B 6 38.112 24.590 31.069 1.00 72.23 N ATOM 1646 C2 C B 6 37.575 25.031 32.282 1.00 80.03 C ATOM 1647 O2 C B 6 38.077 24.626 33.344 1.00 74.09 O ATOM 1648 N3 C B 6 36.545 25.907 32.267 1.00 82.42 N ATOM 1649 C4 C B 6 36.032 26.313 31.103 1.00 86.12 C ATOM 1650 N4 C B 6 35.020 27.179 31.138 1.00 93.77 N ATOM 1651 C5 C B 6 36.535 25.846 29.853 1.00 81.33 C ATOM 1652 C6 C B 6 37.552 24.978 29.883 1.00 72.84 C ATOM 1653 P U B 7 40.929 19.514 31.731 1.00 53.44 P ATOM 1654 OP1 U B 7 39.814 18.664 31.208 1.00 51.42 O ATOM 1655 OP2 U B 7 41.466 19.269 33.093 1.00 55.92 O ATOM 1656 O5' U B 7 42.098 19.445 30.654 1.00 48.56 O ATOM 1657 C5' U B 7 43.461 19.758 30.982 1.00 49.32 C ATOM 1658 C4' U B 7 44.314 19.504 29.765 1.00 49.58 C ATOM 1659 O4' U B 7 44.204 18.095 29.401 1.00 50.23 O ATOM 1660 C3' U B 7 43.923 20.293 28.517 1.00 49.52 C ATOM 1661 O3' U B 7 45.090 20.579 27.766 1.00 57.77 O ATOM 1662 C2' U B 7 43.038 19.323 27.739 1.00 45.98 C ATOM 1663 O2' U B 7 42.979 19.565 26.349 1.00 39.75 O ATOM 1664 C1' U B 7 43.686 17.976 28.081 1.00 47.07 C ATOM 1665 N1 U B 7 42.737 16.849 28.046 1.00 44.68 N ATOM 1666 C2 U B 7 43.041 15.758 27.249 1.00 42.39 C ATOM 1667 O2 U B 7 44.063 15.678 26.584 1.00 44.85 O ATOM 1668 N3 U B 7 42.086 14.774 27.237 1.00 40.77 N ATOM 1669 C4 U B 7 40.902 14.748 27.949 1.00 42.77 C ATOM 1670 O4 U B 7 40.158 13.779 27.841 1.00 42.31 O ATOM 1671 C5 U B 7 40.673 15.898 28.770 1.00 38.81 C ATOM 1672 C6 U B 7 41.573 16.885 28.788 1.00 37.55 C ATOM 1673 P U B 8 45.614 22.076 27.654 1.00 67.13 P ATOM 1674 OP1 U B 8 44.675 22.959 28.416 1.00 70.66 O ATOM 1675 OP2 U B 8 45.863 22.331 26.212 1.00 70.16 O ATOM 1676 O5' U B 8 47.013 22.025 28.422 1.00 66.26 O ATOM 1677 C5' U B 8 47.178 22.571 29.752 1.00 71.31 C ATOM 1678 C4' U B 8 48.559 22.257 30.277 1.00 70.38 C ATOM 1679 O4' U B 8 48.872 20.871 29.976 1.00 65.39 O ATOM 1680 C3' U B 8 49.704 23.100 29.710 1.00 70.74 C ATOM 1681 O3' U B 8 50.565 23.585 30.745 1.00 68.09 O ATOM 1682 C2' U B 8 50.377 22.171 28.699 1.00 68.09 C ATOM 1683 O2' U B 8 51.766 22.357 28.555 1.00 75.91 O ATOM 1684 C1' U B 8 50.112 20.792 29.296 1.00 68.89 C ATOM 1685 N1 U B 8 50.014 19.736 28.273 1.00 70.50 N ATOM 1686 C2 U B 8 51.105 18.904 28.077 1.00 65.72 C ATOM 1687 O2 U B 8 52.144 19.015 28.702 1.00 62.06 O ATOM 1688 N3 U B 8 50.928 17.938 27.115 1.00 63.63 N ATOM 1689 C4 U B 8 49.804 17.728 26.333 1.00 71.37 C ATOM 1690 O4 U B 8 49.799 16.813 25.505 1.00 66.94 O ATOM 1691 C5 U B 8 48.723 18.631 26.590 1.00 71.96 C ATOM 1692 C6 U B 8 48.863 19.585 27.521 1.00 74.91 C TER 1693 U B 8 HETATM 1694 O HOH A 201 19.775 35.747 -7.964 1.00 46.94 O HETATM 1695 O HOH A 202 11.302 37.091 12.845 1.00 38.23 O HETATM 1696 O HOH A 203 21.957 29.614 12.595 1.00 42.45 O HETATM 1697 O HOH A 204 21.935 3.780 18.700 1.00 46.32 O HETATM 1698 O HOH A 205 14.778 7.761 28.186 1.00 40.57 O HETATM 1699 O HOH A 206 9.395 18.213 21.952 1.00 35.45 O HETATM 1700 O HOH A 207 20.381 16.862 32.110 1.00 35.76 O HETATM 1701 O HOH A 208 -0.825 26.465 10.106 1.00 37.57 O HETATM 1702 O HOH A 209 10.388 40.688 -5.276 1.00 44.49 O HETATM 1703 O HOH A 210 15.040 22.651 14.359 1.00 31.02 O HETATM 1704 O HOH A 211 11.066 19.437 8.993 1.00 39.46 O HETATM 1705 O HOH A 212 14.918 15.769 30.039 1.00 28.80 O HETATM 1706 O HOH A 213 5.607 35.224 4.842 1.00 38.70 O HETATM 1707 O HOH A 214 26.087 14.267 19.741 1.00 32.79 O HETATM 1708 O HOH A 215 20.625 18.882 12.293 1.00 34.29 O HETATM 1709 O HOH A 216 14.066 28.995 12.832 1.00 31.19 O HETATM 1710 O HOH A 217 10.261 37.853 -7.191 1.00 37.05 O HETATM 1711 O HOH A 218 15.138 20.873 34.065 1.00 31.05 O HETATM 1712 O HOH A 219 30.111 22.055 15.133 1.00 39.13 O HETATM 1713 O HOH A 220 16.850 39.327 -6.728 1.00 32.35 O HETATM 1714 O HOH A 221 24.464 36.946 11.194 1.00 48.00 O HETATM 1715 O HOH A 222 12.504 18.233 1.592 1.00 44.08 O HETATM 1716 O HOH A 223 14.597 31.279 19.718 1.00 44.99 O HETATM 1717 O HOH A 224 19.645 32.337 8.600 1.00 28.84 O HETATM 1718 O HOH A 225 13.383 6.235 11.581 1.00 42.69 O HETATM 1719 O HOH A 226 14.855 19.172 36.209 1.00 33.47 O HETATM 1720 O HOH A 227 11.342 26.658 -8.592 1.00 45.67 O HETATM 1721 O HOH A 228 19.261 10.499 5.160 1.00 39.17 O HETATM 1722 O HOH A 229 20.400 31.939 11.402 1.00 39.15 O HETATM 1723 O HOH A 230 19.612 17.655 2.851 1.00 38.69 O HETATM 1724 O HOH A 231 21.964 20.312 5.293 1.00 40.87 O HETATM 1725 O HOH A 232 6.089 26.535 -9.979 1.00 48.44 O HETATM 1726 O HOH B 101 48.803 25.529 30.464 1.00 53.44 O MASTER 309 0 0 9 11 0 0 6 1693 2 0 16 END
Display Options:
Goto PDB code:
3D presentation of molecule is powered by
3Dmol
, which supports all modern browsers and mobile devices via WebGL.
Hold mouse button:
left to rotate,middle to shift,right to zoom
Related entries of code: 5wwg
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
5en1
RCSB PDB
PDBbind
184aa, >5EN1_1|Chain... *
5ho4
RCSB PDB
PDBbind
179aa, >5HO4_1|Chain... at 100%
5wwe
RCSB PDB
PDBbind
184aa, >5WWE_1|Chain... at 100%
5wwf
RCSB PDB
PDBbind
184aa, >5WWF_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
5wwg
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNPA2B1
Ligand Name
10-bp RNA mutant A7U
EC.Number
E.C.-.-.-.-
Resolution
2.03(Å)
Affinity (Kd/Ki/IC50)
Kd=219.8nM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) Nat Commun Vol. 9: pp. 420-420
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P22626
Entrez Gene ID
NCBI Entrez Gene ID:
3181
ASD
Information of known allosteric effects of PDB entries
This site has been visited
times since Nov 2007.
Copyright ©2007-2024 涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃 缃戠珯澶囨鍙凤細
娌狪CP澶2021015625鍙-3
娌叕缃戝畨澶囷細
姝ｅ湪鐢宠涓
Technical Support锛堟妧鏈敮鎸侊級:
yingsaisi@foxmail.com
times since Nov 2007. 
娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓