Browse entries in the PDBbind-CN Database
HEADER RNA BINDING PROTEIN/RNA 01-JAN-17 5WWE TITLE CRYSTAL STRUCTURE OF HNRNPA2B1 IN COMPLEX WITH RNA COMPND MOL_ID: 1; COMPND 2 MOLECULE: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: RRMS (UNP RESIDUES 12-195); COMPND 5 SYNONYM: HNRNP A2/B1; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3'); COMPND 9 CHAIN: B; COMPND 10 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: HNRNPA2B1, HNRPA2B1; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 MOL_ID: 2; SOURCE 9 SYNTHETIC: YES; SOURCE 10 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 11 ORGANISM_TAXID: 32630 KEYWDS HNRNP, RRM, RNA BINDING PROTEIN-RNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR B.X.WU,S.C.SU,J.B.MA REVDAT 3 14-FEB-18 5WWE 1 JRNL REVDAT 2 07-FEB-18 5WWE 1 JRNL REVDAT 1 17-JAN-18 5WWE 0 JRNL AUTH B.WU,S.SU,D.P.PATIL,H.LIU,J.GAN,S.R.JAFFREY,J.MA JRNL TITL MOLECULAR BASIS FOR THE SPECIFIC AND MULTIVARIANT JRNL TITL 2 RECOGNITIONS OF RNA SUBSTRATES BY HUMAN HNRNP A2/B1. JRNL REF NAT COMMUN V. 9 420 2018 JRNL REFN ESSN 2041-1723 JRNL PMID 29379020 JRNL DOI 10.1038/S41467-017-02770-Z REMARK 2 REMARK 2 RESOLUTION. 2.40 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.8.0135 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.40 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 30.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 COMPLETENESS FOR RANGE (%) : 99.8 REMARK 3 NUMBER OF REFLECTIONS : 7719 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.227 REMARK 3 R VALUE (WORKING SET) : 0.224 REMARK 3 FREE R VALUE : 0.274 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.800 REMARK 3 FREE R VALUE TEST SET COUNT : 385 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.40 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.46 REMARK 3 REFLECTION IN BIN (WORKING SET) : 556 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 98.31 REMARK 3 BIN R VALUE (WORKING SET) : 0.3370 REMARK 3 BIN FREE R VALUE SET COUNT : 26 REMARK 3 BIN FREE R VALUE : 0.3430 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 1408 REMARK 3 NUCLEIC ACID ATOMS : 199 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 6 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 68.28 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : -1.01000 REMARK 3 B22 (A**2) : -1.01000 REMARK 3 B33 (A**2) : 2.01000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.648 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.309 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.301 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 13.410 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.949 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.938 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1686 ; 0.012 ; 0.018 REMARK 3 BOND LENGTHS OTHERS (A): 1488 ; 0.002 ; 0.020 REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 2308 ; 1.581 ; 1.837 REMARK 3 BOND ANGLES OTHERS (DEGREES): 3436 ; 1.067 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 177 ; 7.481 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 76 ;35.555 ;22.632 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 273 ;19.498 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 16 ;22.546 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 239 ; 0.097 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 1757 ; 0.008 ; 0.020 REMARK 3 GENERAL PLANES OTHERS (A): 407 ; 0.002 ; 0.020 REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 706 ; 5.054 ; 6.697 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): 705 ; 5.056 ; 6.694 REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 882 ; 7.487 ;10.015 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): 883 ; 7.483 ;10.019 REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 980 ; 5.082 ; 7.098 REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): 976 ; 5.037 ; 7.086 REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): 1423 ; 7.542 ;10.517 REMARK 3 LONG RANGE B REFINED ATOMS (A**2): 1872 ;10.377 ;54.432 REMARK 3 LONG RANGE B OTHER ATOMS (A**2): 1873 ;10.376 ;54.468 REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.20 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS REMARK 4 REMARK 4 5WWE COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 06-JAN-17. REMARK 100 THE DEPOSITION ID IS D_1300002506. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 13-OCT-16 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 5.5 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : SSRF REMARK 200 BEAMLINE : BL18U1 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.97776 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS3 S 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO REMARK 200 DATA SCALING SOFTWARE : HKL-3000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 8124 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.400 REMARK 200 RESOLUTION RANGE LOW (A) : 30.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 100.0 REMARK 200 DATA REDUNDANCY : 13.40 REMARK 200 R MERGE (I) : NULL REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 2.3330 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.40 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.44 REMARK 200 COMPLETENESS FOR SHELL (%) : NULL REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : NULL REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: 5EN1 REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 42.06 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.12 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 0.1M SODIUM CITRATE/CITRIC ACID PH REMARK 280 5.5, 20% PEG 3000, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE REMARK 280 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 43 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -Y,X,Z+3/4 REMARK 290 4555 Y,-X,Z+1/4 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 26.52150 REMARK 290 SMTRY1 3 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 39.78225 REMARK 290 SMTRY1 4 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 13.26075 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 1210 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 11590 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: 0.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 ARG A 12 REMARK 465 LYS A 13 REMARK 465 LYS A 14 REMARK 465 GLN A 148 REMARK 465 SER A 149 REMARK 465 GLY A 150 REMARK 465 GLU A 192 REMARK 465 MET A 193 REMARK 465 GLN A 194 REMARK 465 GLU A 195 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 C B 10 C5' C4' O4' C3' O3' C2' O2' REMARK 470 C B 10 C1' N1 C2 O2 N3 C4 N4 REMARK 470 C B 10 C5 C6 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 ARG A 89 NE - CZ - NH2 ANGL. DEV. = 3.5 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 GLN A 43 1.74 -65.75 REMARK 500 ASP A 49 148.75 -173.20 REMARK 500 VAL A 51 124.27 -173.54 REMARK 500 GLU A 100 -45.08 -21.59 REMARK 500 LYS A 120 -174.09 60.35 REMARK 500 ASP A 122 32.58 -91.44 REMARK 500 ASP A 146 -89.38 -131.79 REMARK 500 LYS A 152 117.52 -178.24 REMARK 500 ASN A 181 92.67 -69.31 REMARK 500 SER A 189 -124.84 -56.75 REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 5WWF RELATED DB: PDB REMARK 900 RELATED ID: 5WWG RELATED DB: PDB REMARK 900 RELATED ID: 5WWH RELATED DB: PDB DBREF 5WWE A 12 195 UNP P22626 ROA2_HUMAN 12 195 DBREF 5WWE B 1 10 PDB 5WWE 5WWE 1 10 SEQRES 1 A 184 ARG LYS LYS ARG GLU LYS GLU GLN PHE ARG LYS LEU PHE SEQRES 2 A 184 ILE GLY GLY LEU SER PHE GLU THR THR GLU GLU SER LEU SEQRES 3 A 184 ARG ASN TYR TYR GLU GLN TRP GLY LYS LEU THR ASP CYS SEQRES 4 A 184 VAL VAL MET ARG ASP PRO ALA SER LYS ARG SER ARG GLY SEQRES 5 A 184 PHE GLY PHE VAL THR PHE SER SER MET ALA GLU VAL ASP SEQRES 6 A 184 ALA ALA MET ALA ALA ARG PRO HIS SER ILE ASP GLY ARG SEQRES 7 A 184 VAL VAL GLU PRO LYS ARG ALA VAL ALA ARG GLU GLU SER SEQRES 8 A 184 GLY LYS PRO GLY ALA HIS VAL THR VAL LYS LYS LEU PHE SEQRES 9 A 184 VAL GLY GLY ILE LYS GLU ASP THR GLU GLU HIS HIS LEU SEQRES 10 A 184 ARG ASP TYR PHE GLU GLU TYR GLY LYS ILE ASP THR ILE SEQRES 11 A 184 GLU ILE ILE THR ASP ARG GLN SER GLY LYS LYS ARG GLY SEQRES 12 A 184 PHE GLY PHE VAL THR PHE ASP ASP HIS ASP PRO VAL ASP SEQRES 13 A 184 LYS ILE VAL LEU GLN LYS TYR HIS THR ILE ASN GLY HIS SEQRES 14 A 184 ASN ALA GLU VAL ARG LYS ALA LEU SER ARG GLN GLU MET SEQRES 15 A 184 GLN GLU SEQRES 1 B 10 A G G G A C U A G C FORMUL 3 HOH *6(H2 O) HELIX 1 AA1 LYS A 17 PHE A 20 5 4 HELIX 2 AA2 THR A 33 GLU A 42 1 10 HELIX 3 AA3 GLN A 43 GLY A 45 5 3 HELIX 4 AA4 SER A 71 ALA A 81 1 11 HELIX 5 AA5 ALA A 98 SER A 102 5 5 HELIX 6 AA6 GLU A 124 GLU A 133 1 10 HELIX 7 AA7 ASP A 162 VAL A 170 1 9 SHEET 1 AA1 4 LEU A 47 ARG A 54 0 SHEET 2 AA1 4 SER A 61 PHE A 69 -1 O THR A 68 N THR A 48 SHEET 3 AA1 4 LYS A 22 GLY A 26 -1 N ILE A 25 O GLY A 65 SHEET 4 AA1 4 GLU A 92 ARG A 95 -1 O LYS A 94 N PHE A 24 SHEET 1 AA2 2 SER A 85 ILE A 86 0 SHEET 2 AA2 2 ARG A 89 VAL A 90 -1 O ARG A 89 N ILE A 86 SHEET 1 AA3 5 ILE A 138 ILE A 143 0 SHEET 2 AA3 5 PHE A 155 PHE A 160 -1 O THR A 159 N ASP A 139 SHEET 3 AA3 5 LYS A 113 GLY A 117 -1 N VAL A 116 O GLY A 156 SHEET 4 AA3 5 HIS A 180 LYS A 186 -1 O ARG A 185 N PHE A 115 SHEET 5 AA3 5 TYR A 174 ILE A 177 -1 N HIS A 175 O ALA A 182 CISPEP 1 ARG A 82 PRO A 83 0 7.51 CISPEP 2 ARG A 190 GLN A 191 0 5.57 CRYST1 62.591 62.591 53.043 90.00 90.00 90.00 P 43 4 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.015977 0.000000 0.000000 0.00000 SCALE2 0.000000 0.015977 0.000000 0.00000 SCALE3 0.000000 0.000000 0.018853 0.00000 ATOM 1 N ARG A 15 -5.649 20.241 19.111 1.00105.55 N ATOM 2 CA ARG A 15 -6.079 19.297 18.032 1.00102.42 C ATOM 3 C ARG A 15 -5.744 19.918 16.686 1.00 94.43 C ATOM 4 O ARG A 15 -5.820 21.139 16.545 1.00 94.69 O ATOM 5 CB ARG A 15 -7.589 19.024 18.133 1.00105.29 C ATOM 6 CG ARG A 15 -8.034 17.639 17.652 1.00102.98 C ATOM 7 CD ARG A 15 -9.540 17.423 17.843 1.00 90.47 C ATOM 8 NE ARG A 15 -9.854 16.124 18.459 1.00 89.30 N ATOM 9 CZ ARG A 15 -11.021 15.790 19.040 1.00 90.54 C ATOM 10 NH1 ARG A 15 -11.170 14.578 19.577 1.00 90.92 N ATOM 11 NH2 ARG A 15 -12.051 16.635 19.099 1.00 83.50 N ATOM 12 N GLU A 16 -5.397 19.073 15.709 1.00 90.35 N ATOM 13 CA GLU A 16 -4.961 19.505 14.356 1.00 81.92 C ATOM 14 C GLU A 16 -6.066 20.260 13.610 1.00 79.84 C ATOM 15 O GLU A 16 -7.251 20.074 13.879 1.00 74.74 O ATOM 16 CB GLU A 16 -4.538 18.295 13.504 1.00 80.15 C ATOM 17 CG GLU A 16 -3.370 17.473 14.056 1.00 77.43 C ATOM 18 CD GLU A 16 -3.305 16.058 13.512 1.00 77.66 C ATOM 19 OE1 GLU A 16 -4.337 15.534 13.042 1.00 74.39 O ATOM 20 OE2 GLU A 16 -2.204 15.465 13.555 1.00 79.54 O ATOM 21 N LYS A 17 -5.667 21.117 12.674 1.00 83.31 N ATOM 22 CA LYS A 17 -6.622 21.887 11.848 1.00 85.40 C ATOM 23 C LYS A 17 -7.606 20.922 11.153 1.00 78.54 C ATOM 24 O LYS A 17 -7.202 19.839 10.699 1.00 77.98 O ATOM 25 CB LYS A 17 -5.859 22.726 10.813 1.00 87.29 C ATOM 26 CG LYS A 17 -6.648 23.841 10.135 1.00 98.56 C ATOM 27 CD LYS A 17 -5.701 24.717 9.309 1.00106.15 C ATOM 28 CE LYS A 17 -6.402 25.782 8.462 1.00108.12 C ATOM 29 NZ LYS A 17 -6.734 25.337 7.074 1.00104.45 N ATOM 30 N GLU A 18 -8.885 21.288 11.131 1.00 66.88 N ATOM 31 CA GLU A 18 -9.942 20.428 10.539 1.00 69.71 C ATOM 32 C GLU A 18 -9.655 20.043 9.079 1.00 59.05 C ATOM 33 O GLU A 18 -9.765 18.880 8.697 1.00 55.15 O ATOM 34 CB GLU A 18 -11.340 21.071 10.665 1.00 75.32 C ATOM 35 CG GLU A 18 -12.244 20.882 9.447 1.00 80.44 C ATOM 36 CD GLU A 18 -13.587 21.560 9.571 1.00 79.42 C ATOM 37 OE1 GLU A 18 -13.856 22.481 8.742 1.00 78.40 O ATOM 38 OE2 GLU A 18 -14.354 21.156 10.479 1.00 67.57 O ATOM 39 N GLN A 19 -9.238 21.016 8.285 1.00 58.73 N ATOM 40 CA GLN A 19 -8.939 20.807 6.875 1.00 60.72 C ATOM 41 C GLN A 19 -7.952 19.647 6.609 1.00 63.28 C ATOM 42 O GLN A 19 -7.953 19.094 5.516 1.00 71.82 O ATOM 43 CB GLN A 19 -8.438 22.130 6.241 1.00 63.54 C ATOM 44 CG GLN A 19 -9.003 22.486 4.852 1.00 70.60 C ATOM 45 CD GLN A 19 -10.522 22.284 4.722 1.00 72.99 C ATOM 46 OE1 GLN A 19 -11.326 23.047 5.260 1.00 67.98 O ATOM 47 NE2 GLN A 19 -10.906 21.232 4.017 1.00 70.69 N ATOM 48 N PHE A 20 -7.136 19.289 7.606 1.00 59.19 N ATOM 49 CA PHE A 20 -6.115 18.233 7.508 1.00 55.13 C ATOM 50 C PHE A 20 -6.646 16.870 7.964 1.00 49.45 C ATOM 51 O PHE A 20 -6.019 15.853 7.710 1.00 43.41 O ATOM 52 CB PHE A 20 -4.899 18.602 8.382 1.00 65.26 C ATOM 53 CG PHE A 20 -4.050 19.734 7.831 1.00 71.48 C ATOM 54 CD1 PHE A 20 -4.555 21.028 7.719 1.00 74.92 C ATOM 55 CD2 PHE A 20 -2.726 19.502 7.449 1.00 82.85 C ATOM 56 CE1 PHE A 20 -3.772 22.051 7.218 1.00 81.25 C ATOM 57 CE2 PHE A 20 -1.934 20.525 6.945 1.00 83.31 C ATOM 58 CZ PHE A 20 -2.460 21.797 6.830 1.00 88.46 C ATOM 59 N ARG A 21 -7.806 16.880 8.611 1.00 46.01 N ATOM 60 CA ARG A 21 -8.486 15.717 9.142 1.00 52.67 C ATOM 61 C ARG A 21 -9.818 15.327 8.398 1.00 53.81 C ATOM 62 O ARG A 21 -10.523 14.419 8.845 1.00 46.91 O ATOM 63 CB ARG A 21 -8.825 16.031 10.594 1.00 52.86 C ATOM 64 CG ARG A 21 -7.606 16.176 11.464 1.00 56.58 C ATOM 65 CD ARG A 21 -8.021 16.356 12.896 1.00 59.64 C ATOM 66 NE ARG A 21 -8.705 17.633 13.074 1.00 61.85 N ATOM 67 CZ ARG A 21 -9.895 17.820 13.653 1.00 59.44 C ATOM 68 NH1 ARG A 21 -10.626 16.825 14.152 1.00 61.15 N ATOM 69 NH2 ARG A 21 -10.363 19.044 13.725 1.00 60.17 N ATOM 70 N LYS A 22 -10.148 16.004 7.295 1.00 45.01 N ATOM 71 CA LYS A 22 -11.478 15.910 6.682 1.00 45.86 C ATOM 72 C LYS A 22 -11.469 15.341 5.263 1.00 44.43 C ATOM 73 O LYS A 22 -10.739 15.808 4.395 1.00 45.31 O ATOM 74 CB LYS A 22 -12.051 17.316 6.601 1.00 46.65 C ATOM 75 CG LYS A 22 -13.519 17.404 6.261 1.00 48.94 C ATOM 76 CD LYS A 22 -14.058 18.733 6.765 1.00 55.07 C ATOM 77 CE LYS A 22 -15.379 19.125 6.139 1.00 53.77 C ATOM 78 NZ LYS A 22 -15.921 20.391 6.719 1.00 55.72 N ATOM 79 N LEU A 23 -12.336 14.392 5.000 1.00 41.54 N ATOM 80 CA LEU A 23 -12.570 13.938 3.632 1.00 45.46 C ATOM 81 C LEU A 23 -13.880 14.439 3.042 1.00 42.20 C ATOM 82 O LEU A 23 -14.903 14.389 3.703 1.00 41.04 O ATOM 83 CB LEU A 23 -12.645 12.408 3.603 1.00 47.35 C ATOM 84 CG LEU A 23 -11.433 11.708 4.145 1.00 44.15 C ATOM 85 CD1 LEU A 23 -11.682 10.232 4.047 1.00 41.40 C ATOM 86 CD2 LEU A 23 -10.230 12.117 3.314 1.00 48.87 C ATOM 87 N PHE A 24 -13.824 14.847 1.779 1.00 42.77 N ATOM 88 CA PHE A 24 -14.995 14.949 0.885 1.00 41.16 C ATOM 89 C PHE A 24 -15.348 13.543 0.378 1.00 45.33 C ATOM 90 O PHE A 24 -14.465 12.816 -0.064 1.00 42.44 O ATOM 91 CB PHE A 24 -14.642 15.860 -0.304 1.00 42.54 C ATOM 92 CG PHE A 24 -15.629 15.794 -1.429 1.00 44.42 C ATOM 93 CD1 PHE A 24 -15.516 14.825 -2.404 1.00 46.11 C ATOM 94 CD2 PHE A 24 -16.654 16.702 -1.515 1.00 44.74 C ATOM 95 CE1 PHE A 24 -16.439 14.728 -3.420 1.00 48.85 C ATOM 96 CE2 PHE A 24 -17.579 16.621 -2.541 1.00 46.47 C ATOM 97 CZ PHE A 24 -17.484 15.623 -3.487 1.00 44.86 C ATOM 98 N ILE A 25 -16.617 13.150 0.469 1.00 43.35 N ATOM 99 CA ILE A 25 -17.094 11.854 -0.056 1.00 41.54 C ATOM 100 C ILE A 25 -18.134 12.061 -1.177 1.00 42.36 C ATOM 101 O ILE A 25 -19.286 12.417 -0.919 1.00 45.49 O ATOM 102 CB ILE A 25 -17.716 10.975 1.052 1.00 40.92 C ATOM 103 CG1 ILE A 25 -16.877 10.991 2.336 1.00 38.29 C ATOM 104 CG2 ILE A 25 -17.854 9.533 0.559 1.00 40.52 C ATOM 105 CD1 ILE A 25 -15.474 10.389 2.155 1.00 41.93 C ATOM 106 N GLY A 26 -17.706 11.890 -2.417 1.00 40.53 N ATOM 107 CA GLY A 26 -18.578 12.047 -3.576 1.00 40.84 C ATOM 108 C GLY A 26 -19.184 10.732 -4.018 1.00 46.09 C ATOM 109 O GLY A 26 -18.693 9.656 -3.659 1.00 58.84 O ATOM 110 N GLY A 27 -20.254 10.810 -4.792 1.00 41.87 N ATOM 111 CA GLY A 27 -20.823 9.636 -5.481 1.00 38.42 C ATOM 112 C GLY A 27 -21.727 8.866 -4.566 1.00 39.22 C ATOM 113 O GLY A 27 -21.838 7.636 -4.683 1.00 38.91 O ATOM 114 N LEU A 28 -22.282 9.543 -3.569 1.00 40.23 N ATOM 115 CA LEU A 28 -23.084 8.832 -2.564 1.00 46.49 C ATOM 116 C LEU A 28 -24.424 8.486 -3.189 1.00 51.84 C ATOM 117 O LEU A 28 -24.858 9.097 -4.173 1.00 49.36 O ATOM 118 CB LEU A 28 -23.324 9.656 -1.284 1.00 44.31 C ATOM 119 CG LEU A 28 -22.125 9.949 -0.369 1.00 45.98 C ATOM 120 CD1 LEU A 28 -22.577 10.753 0.841 1.00 46.77 C ATOM 121 CD2 LEU A 28 -21.481 8.655 0.073 1.00 44.28 C ATOM 122 N SER A 29 -25.067 7.489 -2.597 1.00 57.81 N ATOM 123 CA SER A 29 -26.422 7.141 -2.964 1.00 57.26 C ATOM 124 C SER A 29 -27.256 8.260 -2.410 1.00 55.84 C ATOM 125 O SER A 29 -26.943 8.806 -1.365 1.00 54.70 O ATOM 126 CB SER A 29 -26.814 5.753 -2.394 1.00 54.09 C ATOM 127 OG SER A 29 -28.201 5.620 -2.206 1.00 49.37 O ATOM 128 N PHE A 30 -28.346 8.575 -3.091 1.00 62.80 N ATOM 129 CA PHE A 30 -29.356 9.538 -2.575 1.00 57.03 C ATOM 130 C PHE A 30 -30.090 8.920 -1.385 1.00 49.91 C ATOM 131 O PHE A 30 -30.714 9.619 -0.645 1.00 56.02 O ATOM 132 CB PHE A 30 -30.290 10.037 -3.699 1.00 50.21 C ATOM 133 CG PHE A 30 -29.545 10.746 -4.772 1.00 50.34 C ATOM 134 CD1 PHE A 30 -28.962 10.050 -5.817 1.00 55.65 C ATOM 135 CD2 PHE A 30 -29.323 12.099 -4.682 1.00 53.88 C ATOM 136 CE1 PHE A 30 -28.188 10.706 -6.775 1.00 56.55 C ATOM 137 CE2 PHE A 30 -28.558 12.758 -5.627 1.00 54.04 C ATOM 138 CZ PHE A 30 -27.988 12.068 -6.675 1.00 53.53 C ATOM 139 N GLU A 31 -29.929 7.625 -1.179 1.00 52.33 N ATOM 140 CA GLU A 31 -30.414 6.940 0.006 1.00 64.82 C ATOM 141 C GLU A 31 -29.471 7.034 1.186 1.00 69.15 C ATOM 142 O GLU A 31 -29.905 6.847 2.328 1.00 76.68 O ATOM 143 CB GLU A 31 -30.625 5.448 -0.287 1.00 73.36 C ATOM 144 CG GLU A 31 -31.786 4.815 0.478 1.00 89.77 C ATOM 145 CD GLU A 31 -33.099 4.820 -0.307 1.00 92.69 C ATOM 146 OE1 GLU A 31 -33.545 5.912 -0.755 1.00 91.86 O ATOM 147 OE2 GLU A 31 -33.676 3.717 -0.477 1.00 92.95 O ATOM 148 N THR A 32 -28.185 7.268 0.941 1.00 62.55 N ATOM 149 CA THR A 32 -27.222 7.186 2.034 1.00 59.80 C ATOM 150 C THR A 32 -27.423 8.283 3.065 1.00 51.05 C ATOM 151 O THR A 32 -27.528 9.460 2.751 1.00 46.74 O ATOM 152 CB THR A 32 -25.772 7.200 1.545 1.00 60.83 C ATOM 153 OG1 THR A 32 -25.605 6.172 0.565 1.00 61.87 O ATOM 154 CG2 THR A 32 -24.799 6.949 2.706 1.00 60.99 C ATOM 155 N THR A 33 -27.446 7.858 4.311 1.00 49.73 N ATOM 156 CA THR A 33 -27.649 8.754 5.408 1.00 57.24 C ATOM 157 C THR A 33 -26.327 9.050 6.092 1.00 64.81 C ATOM 158 O THR A 33 -25.294 8.412 5.820 1.00 57.87 O ATOM 159 CB THR A 33 -28.585 8.099 6.417 1.00 60.39 C ATOM 160 OG1 THR A 33 -28.134 6.767 6.671 1.00 55.09 O ATOM 161 CG2 THR A 33 -30.004 8.035 5.839 1.00 63.42 C ATOM 162 N GLU A 34 -26.383 10.020 6.997 1.00 62.10 N ATOM 163 CA GLU A 34 -25.287 10.286 7.897 1.00 63.83 C ATOM 164 C GLU A 34 -24.985 9.037 8.709 1.00 66.77 C ATOM 165 O GLU A 34 -23.861 8.552 8.695 1.00 64.50 O ATOM 166 CB GLU A 34 -25.610 11.480 8.785 1.00 68.54 C ATOM 167 CG GLU A 34 -25.550 12.748 7.960 1.00 77.65 C ATOM 168 CD GLU A 34 -26.033 14.012 8.655 1.00 87.45 C ATOM 169 OE1 GLU A 34 -26.377 14.971 7.916 1.00 75.60 O ATOM 170 OE2 GLU A 34 -26.046 14.062 9.911 1.00 99.25 O ATOM 171 N GLU A 35 -25.999 8.468 9.336 1.00 63.77 N ATOM 172 CA GLU A 35 -25.801 7.275 10.123 1.00 72.10 C ATOM 173 C GLU A 35 -24.930 6.245 9.416 1.00 69.50 C ATOM 174 O GLU A 35 -23.936 5.827 9.999 1.00 83.60 O ATOM 175 CB GLU A 35 -27.143 6.653 10.512 1.00 79.48 C ATOM 176 CG GLU A 35 -27.053 5.450 11.447 1.00 82.81 C ATOM 177 CD GLU A 35 -27.848 4.269 10.923 1.00 87.53 C ATOM 178 OE1 GLU A 35 -27.359 3.584 9.997 1.00 95.64 O ATOM 179 OE2 GLU A 35 -28.968 4.044 11.413 1.00 75.34 O ATOM 180 N SER A 36 -25.274 5.820 8.192 1.00 66.98 N ATOM 181 CA SER A 36 -24.498 4.722 7.540 1.00 65.35 C ATOM 182 C SER A 36 -23.131 5.190 7.007 1.00 65.64 C ATOM 183 O SER A 36 -22.187 4.407 6.939 1.00 66.71 O ATOM 184 CB SER A 36 -25.324 3.960 6.470 1.00 68.80 C ATOM 185 OG SER A 36 -25.078 4.372 5.137 1.00 72.09 O ATOM 186 N LEU A 37 -23.044 6.469 6.633 1.00 63.00 N ATOM 187 CA LEU A 37 -21.780 7.101 6.327 1.00 61.65 C ATOM 188 C LEU A 37 -20.901 7.073 7.583 1.00 66.91 C ATOM 189 O LEU A 37 -19.795 6.533 7.565 1.00 63.52 O ATOM 190 CB LEU A 37 -22.026 8.522 5.843 1.00 56.32 C ATOM 191 CG LEU A 37 -20.867 9.267 5.205 1.00 57.23 C ATOM 192 CD1 LEU A 37 -20.448 8.581 3.914 1.00 60.23 C ATOM 193 CD2 LEU A 37 -21.194 10.719 4.943 1.00 53.38 C ATOM 194 N ARG A 38 -21.460 7.584 8.680 1.00 73.84 N ATOM 195 CA ARG A 38 -20.836 7.586 10.004 1.00 77.05 C ATOM 196 C ARG A 38 -20.400 6.201 10.408 1.00 73.77 C ATOM 197 O ARG A 38 -19.312 6.036 10.909 1.00 78.59 O ATOM 198 CB ARG A 38 -21.796 8.168 11.055 1.00 85.27 C ATOM 199 CG ARG A 38 -21.245 8.293 12.477 1.00 93.50 C ATOM 200 CD ARG A 38 -22.166 9.126 13.381 1.00 99.80 C ATOM 201 NE ARG A 38 -21.845 10.566 13.371 1.00100.05 N ATOM 202 CZ ARG A 38 -20.864 11.155 14.070 1.00 95.50 C ATOM 203 NH1 ARG A 38 -20.060 10.449 14.874 1.00 97.71 N ATOM 204 NH2 ARG A 38 -20.679 12.474 13.967 1.00 85.67 N ATOM 205 N ASN A 39 -21.240 5.207 10.163 1.00 77.91 N ATOM 206 CA ASN A 39 -20.918 3.826 10.523 1.00 75.17 C ATOM 207 C ASN A 39 -19.773 3.256 9.721 1.00 68.06 C ATOM 208 O ASN A 39 -18.943 2.538 10.264 1.00 70.92 O ATOM 209 CB ASN A 39 -22.143 2.894 10.379 1.00 78.38 C ATOM 210 CG ASN A 39 -23.065 2.943 11.597 1.00 82.01 C ATOM 211 OD1 ASN A 39 -22.633 2.704 12.728 1.00 78.95 O ATOM 212 ND2 ASN A 39 -24.338 3.243 11.371 1.00 86.80 N ATOM 213 N TYR A 40 -19.738 3.526 8.427 1.00 64.17 N ATOM 214 CA TYR A 40 -18.735 2.872 7.579 1.00 60.08 C ATOM 215 C TYR A 40 -17.350 3.482 7.859 1.00 69.90 C ATOM 216 O TYR A 40 -16.385 2.736 8.012 1.00 65.61 O ATOM 217 CB TYR A 40 -19.110 2.987 6.123 1.00 52.76 C ATOM 218 CG TYR A 40 -18.117 2.426 5.137 1.00 54.36 C ATOM 219 CD1 TYR A 40 -17.090 3.225 4.622 1.00 50.95 C ATOM 220 CD2 TYR A 40 -18.215 1.115 4.680 1.00 52.91 C ATOM 221 CE1 TYR A 40 -16.185 2.720 3.701 1.00 50.54 C ATOM 222 CE2 TYR A 40 -17.302 0.593 3.762 1.00 54.63 C ATOM 223 CZ TYR A 40 -16.297 1.406 3.263 1.00 55.19 C ATOM 224 OH TYR A 40 -15.405 0.916 2.330 1.00 57.23 O ATOM 225 N TYR A 41 -17.269 4.817 7.960 1.00 66.80 N ATOM 226 CA TYR A 41 -15.989 5.485 8.233 1.00 64.05 C ATOM 227 C TYR A 41 -15.458 5.340 9.680 1.00 69.40 C ATOM 228 O TYR A 41 -14.283 5.594 9.907 1.00 76.06 O ATOM 229 CB TYR A 41 -15.981 6.967 7.728 1.00 55.86 C ATOM 230 CG TYR A 41 -15.790 7.012 6.226 1.00 52.45 C ATOM 231 CD1 TYR A 41 -14.564 6.692 5.667 1.00 49.09 C ATOM 232 CD2 TYR A 41 -16.867 7.243 5.352 1.00 50.83 C ATOM 233 CE1 TYR A 41 -14.390 6.660 4.294 1.00 52.46 C ATOM 234 CE2 TYR A 41 -16.703 7.201 3.972 1.00 45.38 C ATOM 235 CZ TYR A 41 -15.470 6.929 3.439 1.00 48.57 C ATOM 236 OH TYR A 41 -15.271 6.877 2.068 1.00 43.05 O ATOM 237 N GLU A 42 -16.274 4.891 10.635 1.00 70.70 N ATOM 238 CA GLU A 42 -15.779 4.641 12.013 1.00 69.19 C ATOM 239 C GLU A 42 -14.853 3.425 12.134 1.00 56.35 C ATOM 240 O GLU A 42 -14.049 3.377 13.033 1.00 68.38 O ATOM 241 CB GLU A 42 -16.919 4.591 13.060 1.00 80.55 C ATOM 242 CG GLU A 42 -17.157 5.916 13.788 1.00 81.71 C ATOM 243 CD GLU A 42 -18.430 5.950 14.638 1.00 92.90 C ATOM 244 OE1 GLU A 42 -18.826 7.063 15.066 1.00 99.19 O ATOM 245 OE2 GLU A 42 -19.047 4.886 14.882 1.00 95.28 O ATOM 246 N GLN A 43 -14.882 2.508 11.183 1.00 55.97 N ATOM 247 CA GLN A 43 -13.953 1.374 11.147 1.00 61.21 C ATOM 248 C GLN A 43 -12.461 1.720 10.922 1.00 71.99 C ATOM 249 O GLN A 43 -11.646 0.779 10.741 1.00 64.51 O ATOM 250 CB GLN A 43 -14.398 0.348 10.080 1.00 66.85 C ATOM 251 CG GLN A 43 -13.964 0.600 8.635 1.00 74.55 C ATOM 252 CD GLN A 43 -14.689 -0.283 7.620 1.00 83.10 C ATOM 253 OE1 GLN A 43 -15.366 0.211 6.707 1.00 85.95 O ATOM 254 NE2 GLN A 43 -14.550 -1.598 7.774 1.00 84.93 N ATOM 255 N TRP A 44 -12.138 3.029 10.815 1.00 70.80 N ATOM 256 CA TRP A 44 -10.764 3.550 10.788 1.00 64.47 C ATOM 257 C TRP A 44 -10.539 4.655 11.825 1.00 64.52 C ATOM 258 O TRP A 44 -9.444 5.212 11.904 1.00 63.07 O ATOM 259 CB TRP A 44 -10.388 4.108 9.401 1.00 62.62 C ATOM 260 CG TRP A 44 -10.434 3.130 8.257 1.00 55.72 C ATOM 261 CD1 TRP A 44 -9.536 2.158 7.976 1.00 55.31 C ATOM 262 CD2 TRP A 44 -11.419 3.072 7.232 1.00 56.78 C ATOM 263 NE1 TRP A 44 -9.897 1.479 6.836 1.00 54.21 N ATOM 264 CE2 TRP A 44 -11.057 2.023 6.361 1.00 53.43 C ATOM 265 CE3 TRP A 44 -12.587 3.805 6.963 1.00 61.86 C ATOM 266 CZ2 TRP A 44 -11.824 1.675 5.244 1.00 58.09 C ATOM 267 CZ3 TRP A 44 -13.343 3.461 5.840 1.00 60.21 C ATOM 268 CH2 TRP A 44 -12.957 2.403 5.001 1.00 57.07 C ATOM 269 N GLY A 45 -11.542 5.008 12.610 1.00 57.96 N ATOM 270 CA GLY A 45 -11.269 5.906 13.719 1.00 58.91 C ATOM 271 C GLY A 45 -12.498 6.605 14.214 1.00 60.15 C ATOM 272 O GLY A 45 -13.604 6.317 13.767 1.00 67.38 O ATOM 273 N LYS A 46 -12.281 7.555 15.108 1.00 54.90 N ATOM 274 CA LYS A 46 -13.339 8.296 15.710 1.00 65.60 C ATOM 275 C LYS A 46 -13.626 9.448 14.793 1.00 70.63 C ATOM 276 O LYS A 46 -12.686 10.164 14.408 1.00 74.24 O ATOM 277 CB LYS A 46 -12.881 8.818 17.078 1.00 77.58 C ATOM 278 CG LYS A 46 -13.996 9.400 17.939 1.00 87.85 C ATOM 279 CD LYS A 46 -13.516 9.751 19.353 1.00 98.32 C ATOM 280 CE LYS A 46 -14.356 9.080 20.445 1.00 99.61 C ATOM 281 NZ LYS A 46 -15.811 9.396 20.366 1.00 99.68 N ATOM 282 N LEU A 47 -14.899 9.627 14.432 1.00 60.28 N ATOM 283 CA LEU A 47 -15.310 10.819 13.723 1.00 60.25 C ATOM 284 C LEU A 47 -15.635 11.923 14.702 1.00 58.60 C ATOM 285 O LEU A 47 -16.073 11.669 15.802 1.00 68.74 O ATOM 286 CB LEU A 47 -16.517 10.536 12.825 1.00 64.37 C ATOM 287 CG LEU A 47 -16.388 9.384 11.816 1.00 62.73 C ATOM 288 CD1 LEU A 47 -17.558 9.386 10.831 1.00 58.83 C ATOM 289 CD2 LEU A 47 -15.066 9.412 11.060 1.00 58.40 C ATOM 290 N THR A 48 -15.371 13.154 14.316 1.00 58.80 N ATOM 291 CA THR A 48 -15.753 14.322 15.105 1.00 58.70 C ATOM 292 C THR A 48 -16.821 15.134 14.397 1.00 62.15 C ATOM 293 O THR A 48 -17.243 16.177 14.896 1.00 64.30 O ATOM 294 CB THR A 48 -14.534 15.250 15.357 1.00 62.91 C ATOM 295 OG1 THR A 48 -14.287 16.106 14.228 1.00 58.61 O ATOM 296 CG2 THR A 48 -13.284 14.427 15.668 1.00 66.71 C ATOM 297 N ASP A 49 -17.204 14.683 13.203 1.00 62.59 N ATOM 298 CA ASP A 49 -18.204 15.337 12.385 1.00 59.64 C ATOM 299 C ASP A 49 -18.498 14.452 11.184 1.00 66.20 C ATOM 300 O ASP A 49 -17.606 13.740 10.660 1.00 58.60 O ATOM 301 CB ASP A 49 -17.769 16.728 11.892 1.00 56.17 C ATOM 302 CG ASP A 49 -18.923 17.524 11.293 1.00 58.04 C ATOM 303 OD1 ASP A 49 -20.075 17.297 11.722 1.00 64.10 O ATOM 304 OD2 ASP A 49 -18.706 18.389 10.389 1.00 53.25 O ATOM 305 N CYS A 50 -19.752 14.556 10.750 1.00 71.69 N ATOM 306 CA CYS A 50 -20.339 13.751 9.693 1.00 67.22 C ATOM 307 C CYS A 50 -21.508 14.502 9.100 1.00 71.08 C ATOM 308 O CYS A 50 -22.254 15.181 9.836 1.00 65.42 O ATOM 309 CB CYS A 50 -20.862 12.475 10.290 1.00 62.26 C ATOM 310 SG CYS A 50 -21.153 11.272 9.025 1.00 72.81 S ATOM 311 N VAL A 51 -21.693 14.378 7.787 1.00 68.28 N ATOM 312 CA VAL A 51 -22.736 15.152 7.110 1.00 57.71 C ATOM 313 C VAL A 51 -22.906 14.766 5.640 1.00 59.26 C ATOM 314 O VAL A 51 -21.934 14.835 4.847 1.00 51.27 O ATOM 315 CB VAL A 51 -22.517 16.692 7.238 1.00 51.71 C ATOM 316 CG1 VAL A 51 -21.284 17.160 6.501 1.00 50.79 C ATOM 317 CG2 VAL A 51 -23.736 17.451 6.749 1.00 57.89 C ATOM 318 N VAL A 52 -24.159 14.399 5.305 1.00 55.33 N ATOM 319 CA VAL A 52 -24.661 14.270 3.943 1.00 47.19 C ATOM 320 C VAL A 52 -25.271 15.615 3.616 1.00 45.94 C ATOM 321 O VAL A 52 -26.249 16.009 4.224 1.00 50.00 O ATOM 322 CB VAL A 52 -25.785 13.201 3.822 1.00 50.10 C ATOM 323 CG1 VAL A 52 -26.411 13.180 2.401 1.00 43.19 C ATOM 324 CG2 VAL A 52 -25.296 11.819 4.277 1.00 46.38 C ATOM 325 N AMET A 53 -24.684 16.332 2.664 0.50 46.10 N ATOM 326 N BMET A 53 -24.743 16.286 2.613 0.50 46.37 N ATOM 327 CA AMET A 53 -25.220 17.609 2.239 0.50 47.79 C ATOM 328 CA BMET A 53 -25.211 17.598 2.260 0.50 48.09 C ATOM 329 C AMET A 53 -26.558 17.412 1.515 0.50 56.69 C ATOM 330 C BMET A 53 -26.502 17.553 1.425 0.50 57.62 C ATOM 331 O AMET A 53 -26.683 16.558 0.613 0.50 56.04 O ATOM 332 O BMET A 53 -26.533 16.974 0.325 0.50 60.20 O ATOM 333 CB AMET A 53 -24.219 18.327 1.351 0.50 49.28 C ATOM 334 CB BMET A 53 -24.068 18.283 1.563 0.50 49.42 C ATOM 335 CG AMET A 53 -22.890 18.606 2.052 0.50 52.23 C ATOM 336 CG BMET A 53 -22.851 18.277 2.489 0.50 50.25 C ATOM 337 SD AMET A 53 -22.774 20.235 2.843 0.50 47.02 S ATOM 338 SD BMET A 53 -23.095 19.508 3.792 0.50 48.57 S ATOM 339 CE AMET A 53 -23.801 21.194 1.756 0.50 49.02 C ATOM 340 CE BMET A 53 -23.505 20.868 2.704 0.50 47.07 C ATOM 341 N ARG A 54 -27.562 18.165 1.968 1.00 56.15 N ATOM 342 CA AARG A 54 -28.906 18.096 1.427 0.50 56.22 C ATOM 343 CA BARG A 54 -28.886 18.081 1.391 0.50 56.76 C ATOM 344 C ARG A 54 -29.347 19.415 0.808 1.00 60.93 C ATOM 345 O ARG A 54 -28.853 20.472 1.159 1.00 55.89 O ATOM 346 CB AARG A 54 -29.883 17.696 2.524 0.50 54.10 C ATOM 347 CB BARG A 54 -29.878 17.558 2.422 0.50 55.12 C ATOM 348 CG AARG A 54 -29.826 16.208 2.861 0.50 55.04 C ATOM 349 CG BARG A 54 -29.840 16.032 2.532 0.50 55.87 C ATOM 350 CD AARG A 54 -30.443 15.896 4.212 0.50 52.76 C ATOM 351 CD BARG A 54 -30.504 15.490 3.792 0.50 53.05 C ATOM 352 NE AARG A 54 -30.406 14.474 4.548 0.50 55.69 N ATOM 353 NE BARG A 54 -30.274 14.052 3.972 0.50 56.28 N ATOM 354 CZ AARG A 54 -29.542 13.916 5.395 0.50 56.46 C ATOM 355 CZ BARG A 54 -30.658 13.116 3.106 0.50 59.36 C ATOM 356 NH1AARG A 54 -28.608 14.653 6.004 0.50 56.20 N ATOM 357 NH1BARG A 54 -31.271 13.470 1.985 0.50 56.49 N ATOM 358 NH2AARG A 54 -29.620 12.613 5.640 0.50 55.77 N ATOM 359 NH2BARG A 54 -30.422 11.827 3.355 0.50 60.01 N ATOM 360 N ASP A 55 -30.292 19.343 -0.117 1.00 71.86 N ATOM 361 CA ASP A 55 -30.844 20.539 -0.750 1.00 77.23 C ATOM 362 C ASP A 55 -31.673 21.266 0.317 1.00 79.29 C ATOM 363 O ASP A 55 -32.404 20.601 1.077 1.00 73.48 O ATOM 364 CB ASP A 55 -31.696 20.139 -1.956 1.00 84.81 C ATOM 365 CG ASP A 55 -32.100 21.315 -2.813 1.00 92.00 C ATOM 366 OD1 ASP A 55 -33.162 21.903 -2.522 1.00106.32 O ATOM 367 OD2 ASP A 55 -31.377 21.633 -3.786 1.00 94.41 O ATOM 368 N PRO A 56 -31.514 22.609 0.432 1.00 82.95 N ATOM 369 CA PRO A 56 -32.290 23.418 1.400 1.00 87.52 C ATOM 370 C PRO A 56 -33.817 23.095 1.477 1.00 90.61 C ATOM 371 O PRO A 56 -34.284 22.578 2.518 1.00 78.32 O ATOM 372 CB PRO A 56 -32.033 24.861 0.928 1.00 93.25 C ATOM 373 CG PRO A 56 -30.704 24.820 0.224 1.00 88.97 C ATOM 374 CD PRO A 56 -30.507 23.421 -0.291 1.00 86.09 C ATOM 375 N ALA A 57 -34.562 23.341 0.388 1.00 93.44 N ATOM 376 CA ALA A 57 -36.020 23.083 0.357 1.00 91.08 C ATOM 377 C ALA A 57 -36.320 21.590 0.408 1.00 89.65 C ATOM 378 O ALA A 57 -36.811 21.074 1.420 1.00 89.01 O ATOM 379 CB ALA A 57 -36.672 23.709 -0.877 1.00 90.29 C ATOM 380 N SER A 58 -35.983 20.883 -0.666 1.00 87.72 N ATOM 381 CA SER A 58 -36.381 19.480 -0.794 1.00 85.31 C ATOM 382 C SER A 58 -35.857 18.605 0.332 1.00 75.97 C ATOM 383 O SER A 58 -36.529 17.674 0.702 1.00 63.48 O ATOM 384 CB SER A 58 -35.955 18.908 -2.153 1.00 86.54 C ATOM 385 OG SER A 58 -34.640 19.309 -2.483 1.00 85.39 O ATOM 386 N LYS A 59 -34.667 18.922 0.867 1.00 86.78 N ATOM 387 CA LYS A 59 -33.904 18.041 1.786 1.00 82.42 C ATOM 388 C LYS A 59 -33.487 16.710 1.115 1.00 75.68 C ATOM 389 O LYS A 59 -33.256 15.695 1.796 1.00 72.15 O ATOM 390 CB LYS A 59 -34.654 17.790 3.109 1.00 93.47 C ATOM 391 CG LYS A 59 -34.899 19.025 3.980 1.00 95.59 C ATOM 392 CD LYS A 59 -36.066 18.824 4.961 1.00 97.79 C ATOM 393 CE LYS A 59 -36.005 17.529 5.788 1.00 97.50 C ATOM 394 NZ LYS A 59 -37.266 17.240 6.547 1.00 95.26 N ATOM 395 N ARG A 60 -33.380 16.729 -0.215 1.00 73.33 N ATOM 396 CA ARG A 60 -32.902 15.586 -0.985 1.00 73.37 C ATOM 397 C ARG A 60 -31.371 15.650 -0.978 1.00 68.02 C ATOM 398 O ARG A 60 -30.790 16.741 -0.964 1.00 61.79 O ATOM 399 CB ARG A 60 -33.416 15.655 -2.428 1.00 76.57 C ATOM 400 CG ARG A 60 -33.319 14.336 -3.180 1.00 84.50 C ATOM 401 CD ARG A 60 -33.006 14.525 -4.662 1.00 92.60 C ATOM 402 NE ARG A 60 -33.016 13.240 -5.376 1.00 96.92 N ATOM 403 CZ ARG A 60 -32.463 13.002 -6.570 1.00 99.07 C ATOM 404 NH1 ARG A 60 -31.826 13.961 -7.246 1.00101.39 N ATOM 405 NH2 ARG A 60 -32.543 11.776 -7.098 1.00 95.73 N ATOM 406 N SER A 61 -30.726 14.490 -1.016 1.00 63.12 N ATOM 407 CA SER A 61 -29.276 14.437 -1.049 1.00 58.31 C ATOM 408 C SER A 61 -28.732 15.096 -2.289 1.00 58.51 C ATOM 409 O SER A 61 -29.343 15.045 -3.389 1.00 54.85 O ATOM 410 CB SER A 61 -28.750 13.010 -1.001 1.00 57.03 C ATOM 411 OG SER A 61 -27.352 13.002 -1.282 1.00 59.23 O ATOM 412 N ARG A 62 -27.564 15.710 -2.102 1.00 52.08 N ATOM 413 CA ARG A 62 -26.809 16.261 -3.223 1.00 49.37 C ATOM 414 C ARG A 62 -25.770 15.291 -3.706 1.00 41.56 C ATOM 415 O ARG A 62 -24.993 15.619 -4.563 1.00 43.50 O ATOM 416 CB ARG A 62 -26.199 17.579 -2.842 1.00 50.87 C ATOM 417 CG ARG A 62 -27.277 18.571 -2.454 1.00 59.46 C ATOM 418 CD ARG A 62 -26.692 19.807 -1.827 1.00 57.29 C ATOM 419 NE ARG A 62 -25.737 20.421 -2.726 1.00 57.54 N ATOM 420 CZ ARG A 62 -24.893 21.385 -2.368 1.00 61.94 C ATOM 421 NH1 ARG A 62 -24.908 21.871 -1.114 1.00 60.44 N ATOM 422 NH2 ARG A 62 -24.044 21.882 -3.278 1.00 56.09 N ATOM 423 N GLY A 63 -25.769 14.089 -3.157 1.00 44.95 N ATOM 424 CA GLY A 63 -24.872 13.045 -3.625 1.00 49.49 C ATOM 425 C GLY A 63 -23.434 13.122 -3.143 1.00 45.76 C ATOM 426 O GLY A 63 -22.617 12.388 -3.635 1.00 40.73 O ATOM 427 N PHE A 64 -23.118 14.019 -2.207 1.00 49.39 N ATOM 428 CA PHE A 64 -21.815 14.012 -1.572 1.00 50.44 C ATOM 429 C PHE A 64 -21.902 14.409 -0.111 1.00 49.74 C ATOM 430 O PHE A 64 -22.811 15.071 0.301 1.00 50.00 O ATOM 431 CB PHE A 64 -20.865 14.939 -2.300 1.00 54.07 C ATOM 432 CG PHE A 64 -21.148 16.393 -2.075 1.00 55.70 C ATOM 433 CD1 PHE A 64 -22.061 17.067 -2.882 1.00 55.42 C ATOM 434 CD2 PHE A 64 -20.510 17.089 -1.052 1.00 55.46 C ATOM 435 CE1 PHE A 64 -22.327 18.418 -2.677 1.00 57.52 C ATOM 436 CE2 PHE A 64 -20.753 18.439 -0.855 1.00 55.91 C ATOM 437 CZ PHE A 64 -21.671 19.102 -1.668 1.00 55.29 C ATOM 438 N GLY A 65 -20.947 13.969 0.682 1.00 49.74 N ATOM 439 CA GLY A 65 -20.882 14.413 2.054 1.00 49.66 C ATOM 440 C GLY A 65 -19.452 14.653 2.508 1.00 49.11 C ATOM 441 O GLY A 65 -18.492 14.570 1.725 1.00 39.07 O ATOM 442 N PHE A 66 -19.324 14.909 3.803 1.00 52.52 N ATOM 443 CA PHE A 66 -18.026 15.087 4.443 1.00 49.38 C ATOM 444 C PHE A 66 -17.957 14.261 5.708 1.00 48.82 C ATOM 445 O PHE A 66 -18.978 14.123 6.390 1.00 47.56 O ATOM 446 CB PHE A 66 -17.845 16.543 4.804 1.00 43.75 C ATOM 447 CG PHE A 66 -17.659 17.457 3.626 1.00 43.55 C ATOM 448 CD1 PHE A 66 -16.467 17.456 2.908 1.00 38.64 C ATOM 449 CD2 PHE A 66 -18.647 18.372 3.279 1.00 40.53 C ATOM 450 CE1 PHE A 66 -16.283 18.315 1.839 1.00 41.67 C ATOM 451 CE2 PHE A 66 -18.467 19.220 2.198 1.00 41.29 C ATOM 452 CZ PHE A 66 -17.288 19.209 1.480 1.00 43.47 C ATOM 453 N VAL A 67 -16.772 13.714 6.006 1.00 45.90 N ATOM 454 CA VAL A 67 -16.465 13.142 7.343 1.00 45.50 C ATOM 455 C VAL A 67 -15.128 13.657 7.884 1.00 50.84 C ATOM 456 O VAL A 67 -14.154 13.843 7.102 1.00 48.08 O ATOM 457 CB VAL A 67 -16.427 11.619 7.354 1.00 44.45 C ATOM 458 CG1 VAL A 67 -17.682 11.072 6.706 1.00 48.77 C ATOM 459 CG2 VAL A 67 -15.172 11.070 6.683 1.00 42.12 C ATOM 460 N THR A 68 -15.099 13.895 9.205 1.00 53.43 N ATOM 461 CA THR A 68 -13.928 14.434 9.873 1.00 51.91 C ATOM 462 C THR A 68 -13.477 13.487 10.983 1.00 55.81 C ATOM 463 O THR A 68 -14.237 13.199 11.903 1.00 58.53 O ATOM 464 CB THR A 68 -14.171 15.847 10.380 1.00 54.67 C ATOM 465 OG1 THR A 68 -14.754 16.623 9.335 1.00 53.97 O ATOM 466 CG2 THR A 68 -12.840 16.522 10.785 1.00 56.58 C ATOM 467 N PHE A 69 -12.241 12.984 10.849 1.00 56.92 N ATOM 468 CA PHE A 69 -11.601 12.080 11.822 1.00 54.20 C ATOM 469 C PHE A 69 -10.900 12.877 12.941 1.00 51.95 C ATOM 470 O PHE A 69 -10.738 14.097 12.854 1.00 49.74 O ATOM 471 CB PHE A 69 -10.579 11.201 11.123 1.00 51.12 C ATOM 472 CG PHE A 69 -11.162 10.137 10.255 1.00 55.63 C ATOM 473 CD1 PHE A 69 -11.514 8.898 10.796 1.00 57.88 C ATOM 474 CD2 PHE A 69 -11.305 10.326 8.868 1.00 59.92 C ATOM 475 CE1 PHE A 69 -12.005 7.874 9.992 1.00 58.16 C ATOM 476 CE2 PHE A 69 -11.822 9.311 8.051 1.00 58.02 C ATOM 477 CZ PHE A 69 -12.169 8.081 8.608 1.00 60.02 C ATOM 478 N SER A 70 -10.492 12.199 14.008 1.00 58.50 N ATOM 479 CA SER A 70 -9.855 12.918 15.133 1.00 64.13 C ATOM 480 C SER A 70 -8.409 13.318 14.818 1.00 59.47 C ATOM 481 O SER A 70 -7.928 14.340 15.318 1.00 55.36 O ATOM 482 CB SER A 70 -9.918 12.107 16.407 1.00 65.11 C ATOM 483 OG SER A 70 -9.197 10.922 16.236 1.00 72.32 O ATOM 484 N SER A 71 -7.753 12.546 13.951 1.00 58.32 N ATOM 485 CA SER A 71 -6.403 12.853 13.496 1.00 55.58 C ATOM 486 C SER A 71 -6.166 12.538 12.011 1.00 58.24 C ATOM 487 O SER A 71 -6.921 11.781 11.375 1.00 57.31 O ATOM 488 CB SER A 71 -5.412 12.052 14.354 1.00 52.03 C ATOM 489 OG SER A 71 -5.513 10.682 14.040 1.00 54.39 O ATOM 490 N MET A 72 -5.088 13.106 11.476 1.00 55.87 N ATOM 491 CA MET A 72 -4.622 12.791 10.123 1.00 53.11 C ATOM 492 C MET A 72 -4.224 11.325 9.943 1.00 51.66 C ATOM 493 O MET A 72 -4.408 10.724 8.857 1.00 54.21 O ATOM 494 CB MET A 72 -3.460 13.704 9.740 1.00 55.83 C ATOM 495 CG MET A 72 -3.199 13.770 8.220 1.00 66.23 C ATOM 496 SD MET A 72 -1.888 14.893 7.620 1.00 61.83 S ATOM 497 CE MET A 72 -1.883 16.072 8.967 1.00 51.25 C ATOM 498 N ALA A 73 -3.695 10.720 10.995 1.00 50.72 N ATOM 499 CA ALA A 73 -3.341 9.302 10.923 1.00 53.09 C ATOM 500 C ALA A 73 -4.551 8.408 10.556 1.00 51.55 C ATOM 501 O ALA A 73 -4.433 7.420 9.813 1.00 47.95 O ATOM 502 CB ALA A 73 -2.757 8.858 12.256 1.00 58.84 C ATOM 503 N GLU A 74 -5.710 8.776 11.105 1.00 48.74 N ATOM 504 CA GLU A 74 -6.941 8.044 10.876 1.00 49.14 C ATOM 505 C GLU A 74 -7.357 8.202 9.441 1.00 48.13 C ATOM 506 O GLU A 74 -7.669 7.203 8.775 1.00 49.40 O ATOM 507 CB GLU A 74 -8.025 8.534 11.845 1.00 53.72 C ATOM 508 CG GLU A 74 -7.808 8.000 13.262 1.00 53.79 C ATOM 509 CD GLU A 74 -8.677 8.640 14.337 1.00 57.99 C ATOM 510 OE1 GLU A 74 -9.203 9.767 14.167 1.00 67.09 O ATOM 511 OE2 GLU A 74 -8.822 8.006 15.387 1.00 55.04 O ATOM 512 N VAL A 75 -7.268 9.445 8.955 1.00 48.22 N ATOM 513 CA VAL A 75 -7.645 9.769 7.594 1.00 46.86 C ATOM 514 C VAL A 75 -6.814 8.956 6.662 1.00 46.52 C ATOM 515 O VAL A 75 -7.371 8.420 5.707 1.00 47.33 O ATOM 516 CB VAL A 75 -7.432 11.229 7.206 1.00 49.06 C ATOM 517 CG1 VAL A 75 -7.706 11.423 5.718 1.00 54.02 C ATOM 518 CG2 VAL A 75 -8.322 12.165 7.993 1.00 47.33 C ATOM 519 N ASP A 76 -5.500 8.860 6.910 1.00 47.01 N ATOM 520 CA ASP A 76 -4.596 8.156 5.955 1.00 49.07 C ATOM 521 C ASP A 76 -4.913 6.700 5.807 1.00 47.27 C ATOM 522 O ASP A 76 -4.740 6.121 4.721 1.00 49.97 O ATOM 523 CB ASP A 76 -3.121 8.288 6.334 1.00 49.14 C ATOM 524 CG ASP A 76 -2.595 9.684 6.110 1.00 56.28 C ATOM 525 OD1 ASP A 76 -3.238 10.466 5.379 1.00 58.98 O ATOM 526 OD2 ASP A 76 -1.520 9.999 6.639 1.00 63.11 O ATOM 527 N ALA A 77 -5.362 6.115 6.905 1.00 43.13 N ATOM 528 CA ALA A 77 -5.651 4.698 6.947 1.00 47.85 C ATOM 529 C ALA A 77 -6.906 4.473 6.158 1.00 43.36 C ATOM 530 O ALA A 77 -6.943 3.600 5.314 1.00 47.70 O ATOM 531 CB ALA A 77 -5.836 4.233 8.398 1.00 46.65 C ATOM 532 N ALA A 78 -7.928 5.270 6.467 1.00 47.83 N ATOM 533 CA ALA A 78 -9.152 5.352 5.638 1.00 46.80 C ATOM 534 C ALA A 78 -8.741 5.346 4.200 1.00 43.62 C ATOM 535 O ALA A 78 -9.153 4.443 3.498 1.00 50.29 O ATOM 536 CB ALA A 78 -9.993 6.573 5.981 1.00 44.64 C ATOM 537 N MET A 79 -7.827 6.249 3.792 1.00 44.53 N ATOM 538 CA MET A 79 -7.393 6.367 2.363 1.00 41.28 C ATOM 539 C MET A 79 -6.469 5.266 1.856 1.00 47.24 C ATOM 540 O MET A 79 -6.437 4.966 0.645 1.00 52.42 O ATOM 541 CB MET A 79 -6.761 7.740 2.088 1.00 42.36 C ATOM 542 CG MET A 79 -7.732 8.920 2.258 1.00 46.72 C ATOM 543 SD MET A 79 -9.090 9.041 1.035 1.00 47.38 S ATOM 544 CE MET A 79 -8.222 9.537 -0.453 1.00 41.03 C ATOM 545 N ALA A 80 -5.688 4.676 2.757 1.00 49.52 N ATOM 546 CA ALA A 80 -4.947 3.444 2.455 1.00 50.80 C ATOM 547 C ALA A 80 -5.890 2.262 2.155 1.00 53.18 C ATOM 548 O ALA A 80 -5.498 1.292 1.500 1.00 53.05 O ATOM 549 CB ALA A 80 -4.032 3.090 3.624 1.00 50.22 C ATOM 550 N ALA A 81 -7.126 2.339 2.646 1.00 57.96 N ATOM 551 CA ALA A 81 -8.082 1.231 2.565 1.00 57.52 C ATOM 552 C ALA A 81 -9.137 1.365 1.440 1.00 60.67 C ATOM 553 O ALA A 81 -10.272 0.915 1.631 1.00 53.66 O ATOM 554 CB ALA A 81 -8.754 1.068 3.918 1.00 50.50 C ATOM 555 N ARG A 82 -8.725 1.905 0.277 1.00 58.31 N ATOM 556 CA ARG A 82 -9.598 2.161 -0.876 1.00 60.42 C ATOM 557 C ARG A 82 -9.593 1.001 -1.888 1.00 62.79 C ATOM 558 O ARG A 82 -8.552 0.385 -2.060 1.00 65.88 O ATOM 559 CB ARG A 82 -9.155 3.433 -1.601 1.00 61.68 C ATOM 560 CG ARG A 82 -9.730 4.716 -1.034 1.00 62.12 C ATOM 561 CD ARG A 82 -9.240 5.922 -1.831 1.00 63.05 C ATOM 562 NE ARG A 82 -7.837 6.220 -1.580 1.00 63.57 N ATOM 563 CZ ARG A 82 -6.957 6.718 -2.460 1.00 65.46 C ATOM 564 NH1 ARG A 82 -7.290 7.007 -3.713 1.00 64.95 N ATOM 565 NH2 ARG A 82 -5.705 6.940 -2.074 1.00 61.00 N ATOM 566 N PRO A 83 -10.694 0.738 -2.615 1.00 60.38 N ATOM 567 CA PRO A 83 -11.877 1.579 -2.634 1.00 56.66 C ATOM 568 C PRO A 83 -12.872 1.390 -1.509 1.00 53.79 C ATOM 569 O PRO A 83 -12.782 0.442 -0.767 1.00 55.02 O ATOM 570 CB PRO A 83 -12.544 1.196 -3.966 1.00 60.34 C ATOM 571 CG PRO A 83 -11.392 0.904 -4.847 1.00 62.08 C ATOM 572 CD PRO A 83 -10.511 0.085 -3.931 1.00 62.82 C ATOM 573 N HIS A 84 -13.816 2.326 -1.417 1.00 49.88 N ATOM 574 CA HIS A 84 -14.885 2.278 -0.452 1.00 48.87 C ATOM 575 C HIS A 84 -16.233 2.149 -1.135 1.00 48.15 C ATOM 576 O HIS A 84 -16.428 2.590 -2.257 1.00 50.72 O ATOM 577 CB HIS A 84 -14.922 3.537 0.418 1.00 52.34 C ATOM 578 CG HIS A 84 -13.652 3.823 1.134 1.00 61.98 C ATOM 579 ND1 HIS A 84 -13.313 5.085 1.569 1.00 60.38 N ATOM 580 CD2 HIS A 84 -12.626 3.013 1.482 1.00 65.57 C ATOM 581 CE1 HIS A 84 -12.134 5.035 2.164 1.00 60.98 C ATOM 582 NE2 HIS A 84 -11.700 3.790 2.129 1.00 64.42 N ATOM 583 N SER A 85 -17.180 1.612 -0.387 1.00 46.35 N ATOM 584 CA SER A 85 -18.420 1.171 -0.919 1.00 52.36 C ATOM 585 C SER A 85 -19.355 1.303 0.196 1.00 49.61 C ATOM 586 O SER A 85 -19.081 0.811 1.258 1.00 52.11 O ATOM 587 CB SER A 85 -18.369 -0.297 -1.335 1.00 62.05 C ATOM 588 OG SER A 85 -18.205 -0.409 -2.735 1.00 65.66 O ATOM 589 N ILE A 86 -20.446 2.008 -0.053 1.00 54.36 N ATOM 590 CA ILE A 86 -21.471 2.267 0.943 1.00 60.25 C ATOM 591 C ILE A 86 -22.790 2.161 0.179 1.00 60.31 C ATOM 592 O ILE A 86 -22.927 2.751 -0.907 1.00 59.67 O ATOM 593 CB ILE A 86 -21.302 3.659 1.626 1.00 62.25 C ATOM 594 CG1 ILE A 86 -19.825 3.928 1.994 1.00 64.42 C ATOM 595 CG2 ILE A 86 -22.175 3.739 2.876 1.00 66.18 C ATOM 596 CD1 ILE A 86 -19.590 5.146 2.880 1.00 59.30 C ATOM 597 N ASP A 87 -23.701 1.342 0.708 1.00 66.25 N ATOM 598 CA ASP A 87 -25.020 1.104 0.118 1.00 60.73 C ATOM 599 C ASP A 87 -24.971 0.835 -1.379 1.00 60.38 C ATOM 600 O ASP A 87 -25.736 1.415 -2.140 1.00 65.83 O ATOM 601 CB ASP A 87 -25.935 2.277 0.430 1.00 60.30 C ATOM 602 CG ASP A 87 -26.031 2.544 1.913 1.00 71.84 C ATOM 603 OD1 ASP A 87 -25.847 1.565 2.684 1.00 70.18 O ATOM 604 OD2 ASP A 87 -26.271 3.720 2.307 1.00 75.51 O ATOM 605 N GLY A 88 -24.034 -0.021 -1.787 1.00 55.57 N ATOM 606 CA GLY A 88 -23.972 -0.531 -3.141 1.00 50.26 C ATOM 607 C GLY A 88 -23.303 0.397 -4.128 1.00 63.39 C ATOM 608 O GLY A 88 -23.284 0.107 -5.347 1.00 69.22 O ATOM 609 N ARG A 89 -22.762 1.518 -3.646 1.00 59.02 N ATOM 610 CA ARG A 89 -22.094 2.443 -4.544 1.00 60.00 C ATOM 611 C ARG A 89 -20.666 2.503 -4.069 1.00 59.72 C ATOM 612 O ARG A 89 -20.395 2.525 -2.855 1.00 53.71 O ATOM 613 CB ARG A 89 -22.703 3.870 -4.540 1.00 54.94 C ATOM 614 CG ARG A 89 -24.216 3.973 -4.461 1.00 56.94 C ATOM 615 CD ARG A 89 -24.933 3.804 -5.804 1.00 58.71 C ATOM 616 NE ARG A 89 -25.287 5.067 -6.461 1.00 59.65 N ATOM 617 CZ ARG A 89 -26.514 5.477 -6.833 1.00 62.85 C ATOM 618 NH1 ARG A 89 -26.633 6.657 -7.436 1.00 68.89 N ATOM 619 NH2 ARG A 89 -27.631 4.774 -6.615 1.00 58.12 N ATOM 620 N VAL A 90 -19.778 2.574 -5.049 1.00 55.74 N ATOM 621 CA VAL A 90 -18.409 2.857 -4.843 1.00 53.44 C ATOM 622 C VAL A 90 -18.440 4.378 -4.702 1.00 56.94 C ATOM 623 O VAL A 90 -19.004 5.063 -5.568 1.00 50.02 O ATOM 624 CB VAL A 90 -17.553 2.489 -6.063 1.00 59.03 C ATOM 625 CG1 VAL A 90 -16.079 2.827 -5.805 1.00 65.05 C ATOM 626 CG2 VAL A 90 -17.718 1.021 -6.437 1.00 68.21 C ATOM 627 N VAL A 91 -17.828 4.890 -3.631 1.00 59.06 N ATOM 628 CA VAL A 91 -17.790 6.332 -3.356 1.00 55.22 C ATOM 629 C VAL A 91 -16.419 6.873 -3.717 1.00 51.92 C ATOM 630 O VAL A 91 -15.503 6.101 -3.975 1.00 53.61 O ATOM 631 CB VAL A 91 -18.204 6.684 -1.919 1.00 47.53 C ATOM 632 CG1 VAL A 91 -19.556 6.113 -1.622 1.00 45.07 C ATOM 633 CG2 VAL A 91 -17.203 6.179 -0.880 1.00 57.71 C ATOM 634 N GLU A 92 -16.317 8.196 -3.778 1.00 54.64 N ATOM 635 CA GLU A 92 -15.070 8.888 -4.158 1.00 60.21 C ATOM 636 C GLU A 92 -14.581 9.772 -3.001 1.00 52.83 C ATOM 637 O GLU A 92 -14.944 10.941 -2.894 1.00 45.41 O ATOM 638 CB GLU A 92 -15.279 9.679 -5.453 1.00 65.16 C ATOM 639 CG GLU A 92 -16.017 8.855 -6.525 1.00 74.07 C ATOM 640 CD GLU A 92 -15.852 9.422 -7.928 1.00 81.57 C ATOM 641 OE1 GLU A 92 -15.718 8.589 -8.896 1.00 71.54 O ATOM 642 OE2 GLU A 92 -15.841 10.694 -8.030 1.00 66.12 O ATOM 643 N PRO A 93 -13.764 9.190 -2.103 1.00 52.11 N ATOM 644 CA PRO A 93 -13.223 9.964 -1.010 1.00 47.81 C ATOM 645 C PRO A 93 -12.075 10.747 -1.554 1.00 46.45 C ATOM 646 O PRO A 93 -11.291 10.215 -2.355 1.00 47.01 O ATOM 647 CB PRO A 93 -12.723 8.908 -0.026 1.00 50.40 C ATOM 648 CG PRO A 93 -13.172 7.603 -0.561 1.00 50.48 C ATOM 649 CD PRO A 93 -13.274 7.807 -2.033 1.00 51.42 C ATOM 650 N LYS A 94 -12.028 12.006 -1.153 1.00 42.04 N ATOM 651 CA LYS A 94 -10.999 12.945 -1.511 1.00 44.27 C ATOM 652 C LYS A 94 -10.722 13.831 -0.283 1.00 41.71 C ATOM 653 O LYS A 94 -11.613 14.113 0.519 1.00 37.78 O ATOM 654 CB LYS A 94 -11.410 13.753 -2.748 1.00 49.00 C ATOM 655 CG LYS A 94 -11.791 12.841 -3.931 1.00 56.82 C ATOM 656 CD LYS A 94 -11.714 13.482 -5.310 1.00 66.76 C ATOM 657 CE LYS A 94 -13.077 13.897 -5.880 1.00 74.39 C ATOM 658 NZ LYS A 94 -13.942 12.750 -6.306 1.00 77.84 N ATOM 659 N ARG A 95 -9.460 14.219 -0.122 1.00 43.23 N ATOM 660 CA ARG A 95 -9.062 15.220 0.878 1.00 42.18 C ATOM 661 C ARG A 95 -9.948 16.444 0.645 1.00 45.02 C ATOM 662 O ARG A 95 -10.107 16.860 -0.510 1.00 48.76 O ATOM 663 CB ARG A 95 -7.613 15.667 0.666 1.00 45.56 C ATOM 664 CG ARG A 95 -6.571 14.592 0.433 1.00 50.60 C ATOM 665 CD ARG A 95 -6.347 13.834 1.723 1.00 50.98 C ATOM 666 NE ARG A 95 -5.684 12.562 1.482 1.00 52.28 N ATOM 667 CZ ARG A 95 -4.867 11.951 2.340 1.00 44.56 C ATOM 668 NH1 ARG A 95 -4.580 12.497 3.500 1.00 43.94 N ATOM 669 NH2 ARG A 95 -4.336 10.772 2.025 1.00 41.84 N ATOM 670 N ALA A 96 -10.507 17.027 1.698 1.00 47.80 N ATOM 671 CA ALA A 96 -11.401 18.167 1.532 1.00 50.99 C ATOM 672 C ALA A 96 -10.603 19.408 1.203 1.00 57.36 C ATOM 673 O ALA A 96 -9.737 19.826 1.993 1.00 59.54 O ATOM 674 CB ALA A 96 -12.266 18.398 2.752 1.00 54.06 C ATOM 675 N VAL A 97 -10.883 19.959 0.012 1.00 56.03 N ATOM 676 CA VAL A 97 -10.358 21.258 -0.439 1.00 64.82 C ATOM 677 C VAL A 97 -11.055 22.440 0.262 1.00 64.23 C ATOM 678 O VAL A 97 -12.274 22.559 0.225 1.00 64.34 O ATOM 679 CB VAL A 97 -10.483 21.433 -1.975 1.00 64.36 C ATOM 680 CG1 VAL A 97 -9.864 22.759 -2.403 1.00 66.65 C ATOM 681 CG2 VAL A 97 -9.843 20.239 -2.708 1.00 55.71 C ATOM 682 N ALA A 98 -10.262 23.317 0.880 1.00 63.15 N ATOM 683 CA ALA A 98 -10.764 24.443 1.677 1.00 63.39 C ATOM 684 C ALA A 98 -11.717 25.393 0.898 1.00 60.98 C ATOM 685 O ALA A 98 -11.555 25.579 -0.302 1.00 55.20 O ATOM 686 CB ALA A 98 -9.574 25.223 2.229 1.00 64.00 C ATOM 687 N ARG A 99 -12.700 25.985 1.584 1.00 63.79 N ATOM 688 CA ARG A 99 -13.625 26.982 0.959 1.00 64.67 C ATOM 689 C ARG A 99 -12.889 28.105 0.226 1.00 67.12 C ATOM 690 O ARG A 99 -13.082 28.292 -0.970 1.00 64.78 O ATOM 691 CB ARG A 99 -14.586 27.564 2.002 1.00 59.78 C ATOM 692 CG ARG A 99 -15.713 26.617 2.335 1.00 58.51 C ATOM 693 CD ARG A 99 -16.470 26.958 3.596 1.00 54.12 C ATOM 694 NE ARG A 99 -15.968 26.160 4.712 1.00 60.04 N ATOM 695 CZ ARG A 99 -16.666 25.331 5.504 1.00 62.95 C ATOM 696 NH1 ARG A 99 -17.983 25.134 5.381 1.00 59.05 N ATOM 697 NH2 ARG A 99 -16.016 24.702 6.486 1.00 63.81 N ATOM 698 N GLU A 100 -12.055 28.827 0.973 1.00 78.47 N ATOM 699 CA GLU A 100 -10.955 29.691 0.463 1.00 84.88 C ATOM 700 C GLU A 100 -10.437 29.371 -0.956 1.00 90.52 C ATOM 701 O GLU A 100 -10.236 30.272 -1.781 1.00 96.18 O ATOM 702 CB GLU A 100 -9.758 29.734 1.473 1.00 87.13 C ATOM 703 CG GLU A 100 -9.801 28.727 2.641 1.00 89.52 C ATOM 704 CD GLU A 100 -8.478 28.563 3.407 1.00 94.80 C ATOM 705 OE1 GLU A 100 -8.524 28.389 4.657 1.00 80.29 O ATOM 706 OE2 GLU A 100 -7.396 28.591 2.775 1.00 88.63 O ATOM 707 N GLU A 101 -10.227 28.089 -1.224 1.00 89.98 N ATOM 708 CA GLU A 101 -9.640 27.620 -2.471 1.00 84.22 C ATOM 709 C GLU A 101 -10.661 27.283 -3.545 1.00 89.45 C ATOM 710 O GLU A 101 -10.344 27.325 -4.734 1.00 94.23 O ATOM 711 CB GLU A 101 -8.829 26.363 -2.183 1.00 88.96 C ATOM 712 CG GLU A 101 -7.679 26.563 -1.208 1.00 90.62 C ATOM 713 CD GLU A 101 -6.446 27.152 -1.858 1.00 97.33 C ATOM 714 OE1 GLU A 101 -6.296 27.039 -3.098 1.00102.10 O ATOM 715 OE2 GLU A 101 -5.614 27.723 -1.115 1.00115.22 O ATOM 716 N SER A 102 -11.875 26.927 -3.129 1.00 95.06 N ATOM 717 CA SER A 102 -12.846 26.291 -4.022 1.00 96.20 C ATOM 718 C SER A 102 -13.524 27.338 -4.889 1.00 97.09 C ATOM 719 O SER A 102 -14.600 27.849 -4.570 1.00100.57 O ATOM 720 CB SER A 102 -13.856 25.455 -3.230 1.00 97.21 C ATOM 721 OG SER A 102 -13.226 24.310 -2.679 1.00 80.07 O ATOM 722 N GLY A 103 -12.862 27.622 -6.003 1.00 99.40 N ATOM 723 CA GLY A 103 -13.184 28.751 -6.850 1.00105.19 C ATOM 724 C GLY A 103 -12.291 28.768 -8.078 1.00122.80 C ATOM 725 O GLY A 103 -12.798 28.830 -9.201 1.00133.71 O ATOM 726 N LYS A 104 -10.968 28.703 -7.870 1.00127.33 N ATOM 727 CA LYS A 104 -9.982 28.727 -8.979 1.00130.16 C ATOM 728 C LYS A 104 -9.851 27.393 -9.732 1.00132.88 C ATOM 729 O LYS A 104 -10.235 26.348 -9.202 1.00145.30 O ATOM 730 CB LYS A 104 -8.593 29.143 -8.470 1.00122.85 C ATOM 731 CG LYS A 104 -7.826 28.067 -7.705 1.00114.44 C ATOM 732 CD LYS A 104 -6.951 28.668 -6.624 1.00112.53 C ATOM 733 CE LYS A 104 -7.780 29.004 -5.395 1.00112.51 C ATOM 734 NZ LYS A 104 -7.093 29.938 -4.466 1.00111.33 N ATOM 735 N PRO A 105 -9.295 27.423 -10.966 1.00128.49 N ATOM 736 CA PRO A 105 -8.954 26.166 -11.638 1.00126.21 C ATOM 737 C PRO A 105 -7.895 25.379 -10.877 1.00124.30 C ATOM 738 O PRO A 105 -7.115 25.957 -10.113 1.00126.35 O ATOM 739 CB PRO A 105 -8.406 26.621 -12.999 1.00125.54 C ATOM 740 CG PRO A 105 -9.032 27.946 -13.226 1.00129.98 C ATOM 741 CD PRO A 105 -9.119 28.578 -11.867 1.00129.52 C ATOM 742 N GLY A 106 -7.878 24.068 -11.087 1.00116.77 N ATOM 743 CA GLY A 106 -6.944 23.195 -10.395 1.00113.52 C ATOM 744 C GLY A 106 -7.200 23.095 -8.907 1.00111.26 C ATOM 745 O GLY A 106 -6.258 22.907 -8.147 1.00115.99 O ATOM 746 N ALA A 107 -8.459 23.249 -8.491 1.00102.95 N ATOM 747 CA ALA A 107 -8.858 23.025 -7.109 1.00 98.58 C ATOM 748 C ALA A 107 -9.247 21.560 -6.980 1.00105.23 C ATOM 749 O ALA A 107 -8.610 20.813 -6.229 1.00101.88 O ATOM 750 CB ALA A 107 -10.014 23.928 -6.710 1.00 97.73 C ATOM 751 N HIS A 108 -10.277 21.148 -7.727 1.00105.57 N ATOM 752 CA HIS A 108 -10.729 19.743 -7.732 1.00108.12 C ATOM 753 C HIS A 108 -10.216 18.957 -8.950 1.00105.29 C ATOM 754 O HIS A 108 -10.664 17.829 -9.180 1.00112.72 O ATOM 755 CB HIS A 108 -12.264 19.637 -7.596 1.00109.39 C ATOM 756 CG HIS A 108 -12.832 20.495 -6.503 1.00107.62 C ATOM 757 ND1 HIS A 108 -13.927 21.311 -6.691 1.00113.61 N ATOM 758 CD2 HIS A 108 -12.428 20.699 -5.227 1.00101.11 C ATOM 759 CE1 HIS A 108 -14.183 21.964 -5.571 1.00108.64 C ATOM 760 NE2 HIS A 108 -13.289 21.611 -4.667 1.00 99.74 N ATOM 761 N VAL A 109 -9.285 19.537 -9.723 1.00100.49 N ATOM 762 CA VAL A 109 -8.475 18.752 -10.664 1.00 92.88 C ATOM 763 C VAL A 109 -7.756 17.711 -9.841 1.00 91.28 C ATOM 764 O VAL A 109 -6.998 18.051 -8.930 1.00 88.10 O ATOM 765 CB VAL A 109 -7.464 19.613 -11.442 1.00 30.00 C ATOM 766 CG1 VAL A 109 -6.536 18.733 -12.266 1.00 30.00 C ATOM 767 CG2 VAL A 109 -8.188 20.614 -12.330 1.00 30.00 C ATOM 768 N THR A 110 -8.032 16.451 -10.137 1.00 84.24 N ATOM 769 CA THR A 110 -7.455 15.364 -9.409 1.00 77.24 C ATOM 770 C THR A 110 -6.275 14.953 -10.268 1.00 77.43 C ATOM 771 O THR A 110 -6.426 14.191 -11.200 1.00 74.58 O ATOM 772 CB THR A 110 -8.508 14.276 -9.189 1.00 80.12 C ATOM 773 OG1 THR A 110 -9.490 14.750 -8.258 1.00 83.87 O ATOM 774 CG2 THR A 110 -7.918 13.047 -8.618 1.00 81.20 C ATOM 775 N VAL A 111 -5.106 15.514 -9.962 1.00 78.06 N ATOM 776 CA VAL A 111 -3.915 15.367 -10.792 1.00 69.88 C ATOM 777 C VAL A 111 -2.802 14.723 -9.980 1.00 77.83 C ATOM 778 O VAL A 111 -2.826 14.778 -8.742 1.00 75.35 O ATOM 779 CB VAL A 111 -3.446 16.725 -11.375 1.00 70.95 C ATOM 780 CG1 VAL A 111 -4.644 17.552 -11.831 1.00 69.32 C ATOM 781 CG2 VAL A 111 -2.583 17.523 -10.398 1.00 64.34 C ATOM 782 N LYS A 112 -1.829 14.147 -10.696 1.00 77.10 N ATOM 783 CA LYS A 112 -0.707 13.391 -10.114 1.00 76.27 C ATOM 784 C LYS A 112 0.661 14.102 -10.147 1.00 78.73 C ATOM 785 O LYS A 112 1.625 13.585 -9.581 1.00 80.70 O ATOM 786 CB LYS A 112 -0.568 12.039 -10.830 1.00 82.82 C ATOM 787 CG LYS A 112 -1.678 11.037 -10.525 1.00 82.55 C ATOM 788 CD LYS A 112 -1.361 9.631 -11.040 1.00 77.93 C ATOM 789 CE LYS A 112 -1.721 9.454 -12.513 1.00 79.49 C ATOM 790 NZ LYS A 112 -3.192 9.381 -12.764 1.00 73.04 N ATOM 791 N LYS A 113 0.752 15.258 -10.817 1.00 75.51 N ATOM 792 CA LYS A 113 1.974 16.071 -10.853 1.00 71.32 C ATOM 793 C LYS A 113 1.863 17.311 -9.956 1.00 64.03 C ATOM 794 O LYS A 113 0.790 17.813 -9.726 1.00 58.14 O ATOM 795 CB LYS A 113 2.251 16.534 -12.273 1.00 77.18 C ATOM 796 CG LYS A 113 3.557 17.298 -12.414 1.00 78.64 C ATOM 797 CD LYS A 113 3.869 17.656 -13.851 1.00 78.90 C ATOM 798 CE LYS A 113 5.309 17.314 -14.165 1.00 76.44 C ATOM 799 NZ LYS A 113 5.694 17.992 -15.402 1.00 77.80 N ATOM 800 N LEU A 114 2.995 17.801 -9.471 1.00 66.19 N ATOM 801 CA LEU A 114 3.027 18.845 -8.451 1.00 66.52 C ATOM 802 C LEU A 114 4.138 19.808 -8.783 1.00 64.83 C ATOM 803 O LEU A 114 5.259 19.364 -9.041 1.00 62.69 O ATOM 804 CB LEU A 114 3.305 18.208 -7.095 1.00 64.44 C ATOM 805 CG LEU A 114 3.373 19.146 -5.908 1.00 64.20 C ATOM 806 CD1 LEU A 114 1.981 19.395 -5.354 1.00 64.99 C ATOM 807 CD2 LEU A 114 4.291 18.559 -4.860 1.00 64.62 C ATOM 808 N PHE A 115 3.811 21.107 -8.755 1.00 62.62 N ATOM 809 CA PHE A 115 4.771 22.210 -8.982 1.00 59.03 C ATOM 810 C PHE A 115 5.319 22.691 -7.652 1.00 50.91 C ATOM 811 O PHE A 115 4.555 22.910 -6.740 1.00 56.34 O ATOM 812 CB PHE A 115 4.079 23.363 -9.738 1.00 55.51 C ATOM 813 CG PHE A 115 4.863 24.646 -9.778 1.00 58.23 C ATOM 814 CD1 PHE A 115 4.791 25.550 -8.725 1.00 59.10 C ATOM 815 CD2 PHE A 115 5.636 24.977 -10.880 1.00 61.05 C ATOM 816 CE1 PHE A 115 5.490 26.746 -8.753 1.00 59.95 C ATOM 817 CE2 PHE A 115 6.348 26.172 -10.911 1.00 60.72 C ATOM 818 CZ PHE A 115 6.271 27.060 -9.850 1.00 60.63 C ATOM 819 N VAL A 116 6.620 22.952 -7.598 1.00 50.70 N ATOM 820 CA VAL A 116 7.328 23.333 -6.389 1.00 54.63 C ATOM 821 C VAL A 116 8.210 24.575 -6.575 1.00 57.60 C ATOM 822 O VAL A 116 9.228 24.489 -7.262 1.00 52.99 O ATOM 823 CB VAL A 116 8.246 22.159 -5.957 1.00 55.15 C ATOM 824 CG1 VAL A 116 9.110 22.549 -4.777 1.00 54.10 C ATOM 825 CG2 VAL A 116 7.399 20.925 -5.649 1.00 58.82 C ATOM 826 N GLY A 117 7.873 25.681 -5.891 1.00 55.93 N ATOM 827 CA GLY A 117 8.551 26.984 -6.076 1.00 50.32 C ATOM 828 C GLY A 117 9.141 27.605 -4.822 1.00 53.46 C ATOM 829 O GLY A 117 8.951 27.100 -3.724 1.00 63.05 O ATOM 830 N GLY A 118 9.876 28.700 -4.984 1.00 50.15 N ATOM 831 CA GLY A 118 10.533 29.369 -3.859 1.00 50.68 C ATOM 832 C GLY A 118 11.748 28.610 -3.294 1.00 57.38 C ATOM 833 O GLY A 118 12.191 28.896 -2.170 1.00 52.23 O ATOM 834 N ILE A 119 12.299 27.677 -4.080 1.00 59.57 N ATOM 835 CA ILE A 119 13.443 26.846 -3.655 1.00 68.50 C ATOM 836 C ILE A 119 14.866 27.438 -3.895 1.00 76.58 C ATOM 837 O ILE A 119 15.844 26.914 -3.354 1.00 80.12 O ATOM 838 CB ILE A 119 13.351 25.394 -4.219 1.00 62.16 C ATOM 839 CG1 ILE A 119 13.241 25.345 -5.746 1.00 62.71 C ATOM 840 CG2 ILE A 119 12.158 24.684 -3.614 1.00 66.66 C ATOM 841 CD1 ILE A 119 13.565 23.996 -6.370 1.00 61.29 C ATOM 842 N LYS A 120 14.982 28.518 -4.679 1.00 85.29 N ATOM 843 CA LYS A 120 16.268 29.226 -4.905 1.00 76.48 C ATOM 844 C LYS A 120 17.331 28.327 -5.539 1.00 71.23 C ATOM 845 O LYS A 120 17.011 27.205 -5.937 1.00 66.75 O ATOM 846 CB LYS A 120 16.745 29.897 -3.613 1.00 79.18 C ATOM 847 CG LYS A 120 15.719 30.873 -3.079 1.00 85.24 C ATOM 848 CD LYS A 120 16.299 31.802 -2.022 1.00 93.38 C ATOM 849 CE LYS A 120 15.239 32.793 -1.564 1.00 95.20 C ATOM 850 NZ LYS A 120 15.801 33.887 -0.732 1.00100.57 N ATOM 851 N GLU A 121 18.565 28.826 -5.676 1.00 83.98 N ATOM 852 CA GLU A 121 19.655 28.097 -6.376 1.00 92.14 C ATOM 853 C GLU A 121 20.347 27.000 -5.553 1.00 95.24 C ATOM 854 O GLU A 121 20.929 26.087 -6.135 1.00107.06 O ATOM 855 CB GLU A 121 20.701 29.073 -6.972 1.00 97.87 C ATOM 856 CG GLU A 121 21.574 29.844 -5.979 1.00103.17 C ATOM 857 CD GLU A 121 22.364 30.987 -6.631 1.00107.29 C ATOM 858 OE1 GLU A 121 23.129 30.742 -7.598 1.00 94.76 O ATOM 859 OE2 GLU A 121 22.229 32.138 -6.160 1.00102.83 O ATOM 860 N ASP A 122 20.251 27.059 -4.221 1.00 90.03 N ATOM 861 CA ASP A 122 20.923 26.086 -3.337 1.00 85.28 C ATOM 862 C ASP A 122 20.087 24.850 -2.958 1.00 83.76 C ATOM 863 O ASP A 122 20.261 24.319 -1.856 1.00 86.94 O ATOM 864 CB ASP A 122 21.413 26.798 -2.066 1.00 87.04 C ATOM 865 CG ASP A 122 20.276 27.344 -1.218 1.00 87.32 C ATOM 866 OD1 ASP A 122 19.127 26.925 -1.436 1.00 81.95 O ATOM 867 OD2 ASP A 122 20.530 28.207 -0.349 1.00 91.11 O ATOM 868 N THR A 123 19.213 24.391 -3.864 1.00 78.94 N ATOM 869 CA THR A 123 18.285 23.273 -3.611 1.00 71.16 C ATOM 870 C THR A 123 18.291 22.300 -4.802 1.00 73.75 C ATOM 871 O THR A 123 18.057 22.714 -5.937 1.00 67.12 O ATOM 872 CB THR A 123 16.824 23.783 -3.366 1.00 70.15 C ATOM 873 OG1 THR A 123 16.702 24.393 -2.063 1.00 60.69 O ATOM 874 CG2 THR A 123 15.802 22.651 -3.463 1.00 68.05 C ATOM 875 N GLU A 124 18.453 21.005 -4.510 1.00 79.44 N ATOM 876 CA GLU A 124 18.790 19.958 -5.507 1.00 85.73 C ATOM 877 C GLU A 124 17.738 18.847 -5.650 1.00 81.50 C ATOM 878 O GLU A 124 17.013 18.558 -4.718 1.00 99.52 O ATOM 879 CB GLU A 124 20.134 19.292 -5.144 1.00 93.88 C ATOM 880 CG GLU A 124 21.344 20.225 -5.065 1.00100.98 C ATOM 881 CD GLU A 124 21.986 20.481 -6.420 1.00110.45 C ATOM 882 OE1 GLU A 124 22.424 19.500 -7.066 1.00112.93 O ATOM 883 OE2 GLU A 124 22.058 21.662 -6.833 1.00114.01 O ATOM 884 N GLU A 125 17.712 18.191 -6.808 1.00 81.50 N ATOM 885 CA GLU A 125 16.798 17.071 -7.124 1.00 82.74 C ATOM 886 C GLU A 125 16.635 16.032 -6.002 1.00 88.39 C ATOM 887 O GLU A 125 15.553 15.466 -5.837 1.00 88.76 O ATOM 888 CB GLU A 125 17.271 16.353 -8.401 1.00 83.12 C ATOM 889 CG GLU A 125 16.198 15.522 -9.083 1.00 85.94 C ATOM 890 CD GLU A 125 16.748 14.529 -10.081 1.00 85.67 C ATOM 891 OE1 GLU A 125 16.459 14.659 -11.291 1.00 86.78 O ATOM 892 OE2 GLU A 125 17.460 13.610 -9.643 1.00 88.23 O ATOM 893 N HIS A 126 17.717 15.777 -5.259 1.00 89.20 N ATOM 894 CA HIS A 126 17.691 14.864 -4.109 1.00 84.95 C ATOM 895 C HIS A 126 16.932 15.487 -2.950 1.00 81.91 C ATOM 896 O HIS A 126 16.219 14.765 -2.239 1.00 81.99 O ATOM 897 CB HIS A 126 19.116 14.422 -3.663 1.00 80.31 C ATOM 898 CG HIS A 126 19.784 15.350 -2.686 1.00 76.51 C ATOM 899 ND1 HIS A 126 20.727 16.283 -3.066 1.00 77.86 N ATOM 900 CD2 HIS A 126 19.655 15.478 -1.342 1.00 75.25 C ATOM 901 CE1 HIS A 126 21.136 16.955 -2.004 1.00 74.44 C ATOM 902 NE2 HIS A 126 20.497 16.490 -0.945 1.00 72.93 N ATOM 903 N HIS A 127 17.115 16.801 -2.737 1.00 75.38 N ATOM 904 CA HIS A 127 16.399 17.520 -1.664 1.00 74.50 C ATOM 905 C HIS A 127 14.880 17.282 -1.770 1.00 72.91 C ATOM 906 O HIS A 127 14.197 17.051 -0.763 1.00 67.09 O ATOM 907 CB HIS A 127 16.666 19.037 -1.688 1.00 80.19 C ATOM 908 CG HIS A 127 17.904 19.477 -0.958 1.00 85.21 C ATOM 909 ND1 HIS A 127 19.152 19.503 -1.540 1.00 81.82 N ATOM 910 CD2 HIS A 127 18.068 19.968 0.293 1.00 86.15 C ATOM 911 CE1 HIS A 127 20.036 19.960 -0.670 1.00 86.17 C ATOM 912 NE2 HIS A 127 19.402 20.264 0.446 1.00 83.27 N ATOM 913 N LEU A 128 14.373 17.315 -3.001 1.00 68.38 N ATOM 914 CA LEU A 128 12.961 17.138 -3.248 1.00 67.88 C ATOM 915 C LEU A 128 12.499 15.707 -2.977 1.00 75.68 C ATOM 916 O LEU A 128 11.453 15.532 -2.351 1.00 72.34 O ATOM 917 CB LEU A 128 12.604 17.609 -4.655 1.00 64.25 C ATOM 918 CG LEU A 128 12.909 19.100 -4.888 1.00 62.85 C ATOM 919 CD1 LEU A 128 12.282 19.570 -6.192 1.00 66.75 C ATOM 920 CD2 LEU A 128 12.428 20.000 -3.758 1.00 58.00 C ATOM 921 N ARG A 129 13.277 14.699 -3.388 1.00 80.67 N ATOM 922 CA ARG A 129 12.962 13.296 -3.022 1.00 86.91 C ATOM 923 C ARG A 129 12.863 13.123 -1.502 1.00 84.03 C ATOM 924 O ARG A 129 11.857 12.632 -0.988 1.00 80.09 O ATOM 925 CB ARG A 129 13.993 12.296 -3.584 1.00 90.25 C ATOM 926 CG ARG A 129 13.556 10.828 -3.441 1.00 86.60 C ATOM 927 CD ARG A 129 14.482 9.864 -4.161 1.00 83.11 C ATOM 928 NE ARG A 129 14.616 10.171 -5.588 1.00 77.27 N ATOM 929 CZ ARG A 129 13.841 9.697 -6.566 1.00 81.02 C ATOM 930 NH1 ARG A 129 12.818 8.864 -6.329 1.00 85.41 N ATOM 931 NH2 ARG A 129 14.090 10.072 -7.815 1.00 83.58 N ATOM 932 N ASP A 130 13.912 13.546 -0.804 1.00 79.18 N ATOM 933 CA ASP A 130 13.977 13.461 0.651 1.00 79.82 C ATOM 934 C ASP A 130 12.635 13.867 1.266 1.00 73.01 C ATOM 935 O ASP A 130 12.080 13.165 2.106 1.00 72.60 O ATOM 936 CB ASP A 130 15.111 14.373 1.206 1.00 85.29 C ATOM 937 CG ASP A 130 16.447 13.631 1.475 1.00 93.53 C ATOM 938 OD1 ASP A 130 16.447 12.469 1.967 1.00 96.77 O ATOM 939 OD2 ASP A 130 17.512 14.263 1.259 1.00 91.50 O ATOM 940 N TYR A 131 12.133 15.016 0.831 1.00 66.53 N ATOM 941 CA TYR A 131 10.972 15.624 1.427 1.00 60.82 C ATOM 942 C TYR A 131 9.676 14.922 0.978 1.00 60.58 C ATOM 943 O TYR A 131 8.813 14.660 1.817 1.00 60.41 O ATOM 944 CB TYR A 131 10.947 17.172 1.184 1.00 58.68 C ATOM 945 CG TYR A 131 9.807 17.845 1.926 1.00 50.11 C ATOM 946 CD1 TYR A 131 8.539 17.937 1.362 1.00 47.95 C ATOM 947 CD2 TYR A 131 9.971 18.308 3.208 1.00 50.26 C ATOM 948 CE1 TYR A 131 7.480 18.495 2.057 1.00 47.41 C ATOM 949 CE2 TYR A 131 8.908 18.871 3.912 1.00 55.46 C ATOM 950 CZ TYR A 131 7.660 18.956 3.317 1.00 52.70 C ATOM 951 OH TYR A 131 6.588 19.519 3.988 1.00 60.77 O ATOM 952 N PHE A 132 9.569 14.589 -0.310 1.00 63.84 N ATOM 953 CA PHE A 132 8.291 14.184 -0.912 1.00 71.65 C ATOM 954 C PHE A 132 8.041 12.682 -0.975 1.00 75.53 C ATOM 955 O PHE A 132 6.886 12.249 -1.044 1.00 73.37 O ATOM 956 CB PHE A 132 8.105 14.828 -2.304 1.00 64.64 C ATOM 957 CG PHE A 132 7.729 16.278 -2.235 1.00 58.18 C ATOM 958 CD1 PHE A 132 6.544 16.665 -1.634 1.00 61.65 C ATOM 959 CD2 PHE A 132 8.566 17.258 -2.731 1.00 65.83 C ATOM 960 CE1 PHE A 132 6.202 17.995 -1.521 1.00 64.30 C ATOM 961 CE2 PHE A 132 8.231 18.605 -2.631 1.00 68.34 C ATOM 962 CZ PHE A 132 7.046 18.977 -2.030 1.00 65.41 C ATOM 963 N GLU A 133 9.109 11.899 -0.934 1.00 79.39 N ATOM 964 CA GLU A 133 9.013 10.434 -0.864 1.00 72.65 C ATOM 965 C GLU A 133 8.071 10.001 0.245 1.00 62.41 C ATOM 966 O GLU A 133 7.368 9.016 0.096 1.00 68.87 O ATOM 967 CB GLU A 133 10.399 9.829 -0.614 1.00 76.92 C ATOM 968 CG GLU A 133 10.951 10.170 0.778 1.00 77.99 C ATOM 969 CD GLU A 133 12.436 9.917 0.957 1.00 80.58 C ATOM 970 OE1 GLU A 133 13.051 9.206 0.122 1.00 74.74 O ATOM 971 OE2 GLU A 133 12.968 10.438 1.962 1.00 75.29 O ATOM 972 N GLU A 134 8.053 10.768 1.334 1.00 58.89 N ATOM 973 CA GLU A 134 7.180 10.549 2.486 1.00 62.51 C ATOM 974 C GLU A 134 5.677 10.560 2.172 1.00 65.79 C ATOM 975 O GLU A 134 4.894 10.029 2.946 1.00 73.43 O ATOM 976 CB GLU A 134 7.416 11.641 3.544 1.00 64.66 C ATOM 977 CG GLU A 134 8.805 11.684 4.183 1.00 77.11 C ATOM 978 CD GLU A 134 8.920 10.824 5.436 1.00 84.78 C ATOM 979 OE1 GLU A 134 8.879 9.578 5.299 1.00 75.82 O ATOM 980 OE2 GLU A 134 9.058 11.407 6.550 1.00 87.06 O ATOM 981 N TYR A 135 5.279 11.217 1.086 1.00 62.61 N ATOM 982 CA TYR A 135 3.873 11.490 0.796 1.00 59.16 C ATOM 983 C TYR A 135 3.348 10.372 -0.079 1.00 56.34 C ATOM 984 O TYR A 135 2.201 9.972 0.051 1.00 60.13 O ATOM 985 CB TYR A 135 3.705 12.893 0.137 1.00 53.41 C ATOM 986 CG TYR A 135 3.837 13.998 1.146 1.00 50.21 C ATOM 987 CD1 TYR A 135 5.086 14.522 1.513 1.00 53.73 C ATOM 988 CD2 TYR A 135 2.734 14.496 1.764 1.00 46.28 C ATOM 989 CE1 TYR A 135 5.185 15.517 2.485 1.00 54.09 C ATOM 990 CE2 TYR A 135 2.828 15.466 2.737 1.00 47.18 C ATOM 991 CZ TYR A 135 4.035 15.973 3.109 1.00 50.79 C ATOM 992 OH TYR A 135 4.037 16.959 4.085 1.00 57.77 O ATOM 993 N GLY A 136 4.186 9.878 -0.981 1.00 50.90 N ATOM 994 CA GLY A 136 3.879 8.656 -1.709 1.00 51.63 C ATOM 995 C GLY A 136 5.044 8.325 -2.590 1.00 57.00 C ATOM 996 O GLY A 136 6.040 9.037 -2.582 1.00 65.31 O ATOM 997 N LYS A 137 4.913 7.281 -3.388 1.00 61.43 N ATOM 998 CA LYS A 137 5.986 6.918 -4.287 1.00 70.01 C ATOM 999 C LYS A 137 5.993 7.823 -5.521 1.00 71.47 C ATOM 1000 O LYS A 137 4.918 8.212 -5.996 1.00 72.97 O ATOM 1001 CB LYS A 137 5.888 5.442 -4.679 1.00 79.21 C ATOM 1002 CG LYS A 137 7.200 4.887 -5.231 1.00 90.07 C ATOM 1003 CD LYS A 137 7.522 3.474 -4.753 1.00 96.06 C ATOM 1004 CE LYS A 137 9.031 3.246 -4.761 1.00 99.23 C ATOM 1005 NZ LYS A 137 9.403 1.813 -4.645 1.00101.59 N ATOM 1006 N ILE A 138 7.202 8.112 -6.033 1.00 69.38 N ATOM 1007 CA ILE A 138 7.452 9.058 -7.136 1.00 77.03 C ATOM 1008 C ILE A 138 7.825 8.388 -8.483 1.00 89.76 C ATOM 1009 O ILE A 138 8.466 7.337 -8.501 1.00104.31 O ATOM 1010 CB ILE A 138 8.611 10.010 -6.750 1.00 82.22 C ATOM 1011 CG1 ILE A 138 8.375 10.651 -5.359 1.00 82.46 C ATOM 1012 CG2 ILE A 138 8.825 11.077 -7.828 1.00 85.91 C ATOM 1013 CD1 ILE A 138 9.571 11.406 -4.799 1.00 79.65 C ATOM 1014 N ASP A 139 7.405 8.998 -9.599 1.00 89.79 N ATOM 1015 CA ASP A 139 7.957 8.712 -10.939 1.00 86.27 C ATOM 1016 C ASP A 139 9.254 9.455 -11.103 1.00 81.53 C ATOM 1017 O ASP A 139 10.319 8.874 -11.273 1.00 85.06 O ATOM 1018 CB ASP A 139 7.051 9.250 -12.062 1.00 86.99 C ATOM 1019 CG ASP A 139 5.963 8.309 -12.447 1.00 86.53 C ATOM 1020 OD1 ASP A 139 6.298 7.282 -13.070 1.00 87.18 O ATOM 1021 OD2 ASP A 139 4.781 8.617 -12.165 1.00 84.26 O ATOM 1022 N THR A 140 9.126 10.771 -11.053 1.00 84.53 N ATOM 1023 CA THR A 140 10.099 11.682 -11.614 1.00 93.19 C ATOM 1024 C THR A 140 10.233 12.945 -10.764 1.00 88.40 C ATOM 1025 O THR A 140 9.325 13.302 -10.014 1.00 85.54 O ATOM 1026 CB THR A 140 9.675 12.090 -13.048 1.00 99.17 C ATOM 1027 OG1 THR A 140 8.244 12.199 -13.113 1.00 93.82 O ATOM 1028 CG2 THR A 140 10.149 11.060 -14.085 1.00 95.10 C ATOM 1029 N ILE A 141 11.395 13.583 -10.898 1.00 86.38 N ATOM 1030 CA ILE A 141 11.702 14.898 -10.344 1.00 84.46 C ATOM 1031 C ILE A 141 12.330 15.747 -11.479 1.00 85.23 C ATOM 1032 O ILE A 141 12.883 15.202 -12.432 1.00 84.44 O ATOM 1033 CB ILE A 141 12.643 14.774 -9.119 1.00 87.90 C ATOM 1034 CG1 ILE A 141 12.031 13.804 -8.093 1.00 85.81 C ATOM 1035 CG2 ILE A 141 12.927 16.145 -8.487 1.00 92.93 C ATOM 1036 CD1 ILE A 141 12.698 13.778 -6.728 1.00 88.22 C ATOM 1037 N GLU A 142 12.199 17.071 -11.392 1.00 89.00 N ATOM 1038 CA GLU A 142 12.754 18.006 -12.383 1.00 92.02 C ATOM 1039 C GLU A 142 13.149 19.324 -11.716 1.00 87.96 C ATOM 1040 O GLU A 142 12.271 20.079 -11.314 1.00 88.05 O ATOM 1041 CB GLU A 142 11.704 18.343 -13.466 1.00 97.16 C ATOM 1042 CG GLU A 142 11.408 17.277 -14.512 1.00 98.09 C ATOM 1043 CD GLU A 142 10.494 17.790 -15.618 1.00103.53 C ATOM 1044 OE1 GLU A 142 9.509 17.083 -15.958 1.00 99.59 O ATOM 1045 OE2 GLU A 142 10.760 18.905 -16.142 1.00 92.24 O ATOM 1046 N ILE A 143 14.442 19.615 -11.603 1.00 85.47 N ATOM 1047 CA ILE A 143 14.877 20.985 -11.273 1.00 87.80 C ATOM 1048 C ILE A 143 14.839 21.797 -12.575 1.00 90.00 C ATOM 1049 O ILE A 143 14.965 21.220 -13.657 1.00 99.25 O ATOM 1050 CB ILE A 143 16.291 21.038 -10.647 1.00 86.05 C ATOM 1051 CG1 ILE A 143 16.419 20.032 -9.502 1.00 91.82 C ATOM 1052 CG2 ILE A 143 16.619 22.449 -10.153 1.00 88.44 C ATOM 1053 CD1 ILE A 143 15.305 20.098 -8.485 1.00 96.63 C ATOM 1054 N ILE A 144 14.650 23.116 -12.486 1.00 87.03 N ATOM 1055 CA ILE A 144 14.571 23.954 -13.691 1.00 93.24 C ATOM 1056 C ILE A 144 15.636 25.068 -13.654 1.00 92.52 C ATOM 1057 O ILE A 144 15.892 25.668 -12.607 1.00 89.04 O ATOM 1058 CB ILE A 144 13.135 24.504 -13.904 1.00 96.44 C ATOM 1059 CG1 ILE A 144 12.084 23.371 -13.951 1.00 95.24 C ATOM 1060 CG2 ILE A 144 13.041 25.324 -15.186 1.00 97.76 C ATOM 1061 CD1 ILE A 144 12.078 22.522 -15.211 1.00 91.70 C ATOM 1062 N THR A 145 16.241 25.321 -14.819 1.00 98.49 N ATOM 1063 CA THR A 145 17.451 26.153 -14.987 1.00103.84 C ATOM 1064 C THR A 145 17.564 26.548 -16.472 1.00105.48 C ATOM 1065 O THR A 145 16.836 25.991 -17.305 1.00 99.40 O ATOM 1066 CB THR A 145 18.712 25.324 -14.610 1.00106.82 C ATOM 1067 OG1 THR A 145 18.655 24.927 -13.230 1.00101.95 O ATOM 1068 CG2 THR A 145 20.029 26.078 -14.881 1.00102.87 C ATOM 1069 N ASP A 146 18.443 27.501 -16.815 1.00108.13 N ATOM 1070 CA ASP A 146 18.987 27.558 -18.191 1.00109.54 C ATOM 1071 C ASP A 146 20.529 27.708 -18.285 1.00109.59 C ATOM 1072 O ASP A 146 21.227 26.683 -18.336 1.00102.69 O ATOM 1073 CB ASP A 146 18.221 28.557 -19.068 1.00105.56 C ATOM 1074 CG ASP A 146 18.268 28.176 -20.541 1.00104.69 C ATOM 1075 OD1 ASP A 146 19.372 28.239 -21.140 1.00 96.32 O ATOM 1076 OD2 ASP A 146 17.208 27.775 -21.079 1.00 89.79 O ATOM 1077 N ARG A 147 21.046 28.949 -18.307 1.00100.92 N ATOM 1078 CA ARG A 147 22.492 29.231 -18.442 1.00103.91 C ATOM 1079 C ARG A 147 23.054 28.882 -19.842 1.00102.15 C ATOM 1080 O ARG A 147 23.062 29.711 -20.770 1.00 88.27 O ATOM 1081 CB ARG A 147 23.278 28.497 -17.334 1.00106.52 C ATOM 1082 CG ARG A 147 24.417 29.282 -16.691 1.00111.40 C ATOM 1083 CD ARG A 147 25.799 28.767 -17.089 1.00119.65 C ATOM 1084 NE ARG A 147 26.837 29.117 -16.103 1.00119.53 N ATOM 1085 CZ ARG A 147 28.092 28.641 -16.085 1.00109.15 C ATOM 1086 NH1 ARG A 147 28.930 29.040 -15.135 1.00101.50 N ATOM 1087 NH2 ARG A 147 28.525 27.768 -16.999 1.00112.91 N ATOM 1088 N LYS A 151 21.652 28.999 -14.112 1.00 86.73 N ATOM 1089 CA LYS A 151 22.162 28.348 -12.915 1.00101.11 C ATOM 1090 C LYS A 151 21.073 27.522 -12.250 1.00104.36 C ATOM 1091 O LYS A 151 21.270 26.333 -12.033 1.00112.00 O ATOM 1092 CB LYS A 151 22.725 29.369 -11.915 1.00106.08 C ATOM 1093 CG LYS A 151 23.366 28.755 -10.662 1.00110.30 C ATOM 1094 CD LYS A 151 24.895 28.641 -10.716 1.00106.81 C ATOM 1095 CE LYS A 151 25.413 27.622 -11.720 1.00104.59 C ATOM 1096 NZ LYS A 151 25.814 28.236 -13.021 1.00104.90 N ATOM 1097 N LYS A 152 19.943 28.159 -11.934 1.00 99.55 N ATOM 1098 CA LYS A 152 18.754 27.501 -11.344 1.00 98.82 C ATOM 1099 C LYS A 152 17.610 28.516 -11.144 1.00 94.52 C ATOM 1100 O LYS A 152 17.768 29.444 -10.366 1.00100.16 O ATOM 1101 CB LYS A 152 19.090 26.808 -9.999 1.00 99.35 C ATOM 1102 CG LYS A 152 19.121 25.278 -10.046 1.00101.79 C ATOM 1103 CD LYS A 152 19.622 24.661 -8.739 1.00105.07 C ATOM 1104 CE LYS A 152 21.141 24.662 -8.600 1.00104.71 C ATOM 1105 NZ LYS A 152 21.845 23.800 -9.587 1.00103.35 N ATOM 1106 N ARG A 153 16.468 28.328 -11.813 1.00 87.43 N ATOM 1107 CA ARG A 153 15.323 29.286 -11.720 1.00 88.94 C ATOM 1108 C ARG A 153 14.605 29.387 -10.340 1.00 82.61 C ATOM 1109 O ARG A 153 13.923 30.383 -10.065 1.00 81.66 O ATOM 1110 CB ARG A 153 14.289 29.043 -12.859 1.00 93.24 C ATOM 1111 CG ARG A 153 14.331 30.079 -13.999 1.00 92.35 C ATOM 1112 CD ARG A 153 13.219 29.913 -15.054 1.00 86.53 C ATOM 1113 NE ARG A 153 13.659 29.156 -16.234 1.00 88.60 N ATOM 1114 CZ ARG A 153 12.864 28.605 -17.166 1.00 89.77 C ATOM 1115 NH1 ARG A 153 13.419 27.940 -18.180 1.00 84.48 N ATOM 1116 NH2 ARG A 153 11.527 28.689 -17.108 1.00 87.33 N ATOM 1117 N GLY A 154 14.777 28.382 -9.477 1.00 84.57 N ATOM 1118 CA GLY A 154 14.177 28.362 -8.124 1.00 79.20 C ATOM 1119 C GLY A 154 12.823 27.664 -8.033 1.00 72.19 C ATOM 1120 O GLY A 154 11.995 27.991 -7.146 1.00 57.43 O ATOM 1121 N PHE A 155 12.592 26.713 -8.949 1.00 67.11 N ATOM 1122 CA PHE A 155 11.370 25.910 -8.958 1.00 69.44 C ATOM 1123 C PHE A 155 11.510 24.585 -9.687 1.00 65.34 C ATOM 1124 O PHE A 155 12.515 24.348 -10.326 1.00 67.45 O ATOM 1125 CB PHE A 155 10.147 26.705 -9.468 1.00 75.45 C ATOM 1126 CG PHE A 155 10.147 27.001 -10.947 1.00 78.70 C ATOM 1127 CD1 PHE A 155 9.565 26.105 -11.855 1.00 79.27 C ATOM 1128 CD2 PHE A 155 10.662 28.205 -11.434 1.00 74.12 C ATOM 1129 CE1 PHE A 155 9.526 26.390 -13.220 1.00 75.29 C ATOM 1130 CE2 PHE A 155 10.626 28.488 -12.793 1.00 74.80 C ATOM 1131 CZ PHE A 155 10.054 27.585 -13.687 1.00 70.25 C ATOM 1132 N GLY A 156 10.505 23.718 -9.556 1.00 64.70 N ATOM 1133 CA GLY A 156 10.563 22.400 -10.154 1.00 65.28 C ATOM 1134 C GLY A 156 9.289 21.591 -10.023 1.00 70.43 C ATOM 1135 O GLY A 156 8.305 22.069 -9.454 1.00 68.03 O ATOM 1136 N PHE A 157 9.322 20.364 -10.557 1.00 67.91 N ATOM 1137 CA PHE A 157 8.168 19.465 -10.610 1.00 73.31 C ATOM 1138 C PHE A 157 8.441 18.065 -10.032 1.00 74.77 C ATOM 1139 O PHE A 157 9.591 17.606 -10.029 1.00 61.87 O ATOM 1140 CB PHE A 157 7.711 19.291 -12.042 1.00 81.78 C ATOM 1141 CG PHE A 157 7.299 20.563 -12.704 1.00 90.59 C ATOM 1142 CD1 PHE A 157 8.245 21.367 -13.342 1.00 90.15 C ATOM 1143 CD2 PHE A 157 5.964 20.962 -12.704 1.00 91.79 C ATOM 1144 CE1 PHE A 157 7.872 22.549 -13.966 1.00 92.10 C ATOM 1145 CE2 PHE A 157 5.587 22.143 -13.332 1.00 92.27 C ATOM 1146 CZ PHE A 157 6.542 22.938 -13.962 1.00 88.68 C ATOM 1147 N VAL A 158 7.364 17.415 -9.559 1.00 73.42 N ATOM 1148 CA VAL A 158 7.396 16.092 -8.902 1.00 73.66 C ATOM 1149 C VAL A 158 6.133 15.316 -9.275 1.00 70.82 C ATOM 1150 O VAL A 158 5.037 15.876 -9.271 1.00 73.45 O ATOM 1151 CB VAL A 158 7.475 16.214 -7.352 1.00 77.65 C ATOM 1152 CG1 VAL A 158 7.555 14.829 -6.699 1.00 83.13 C ATOM 1153 CG2 VAL A 158 8.667 17.081 -6.911 1.00 70.53 C ATOM 1154 N THR A 159 6.264 14.027 -9.571 1.00 75.45 N ATOM 1155 CA THR A 159 5.151 13.287 -10.189 1.00 76.86 C ATOM 1156 C THR A 159 4.905 11.955 -9.498 1.00 76.07 C ATOM 1157 O THR A 159 5.742 11.078 -9.535 1.00 74.50 O ATOM 1158 CB THR A 159 5.436 13.073 -11.688 1.00 76.53 C ATOM 1159 OG1 THR A 159 6.157 14.210 -12.206 1.00 77.37 O ATOM 1160 CG2 THR A 159 4.135 12.861 -12.464 1.00 74.44 C ATOM 1161 N PHE A 160 3.742 11.805 -8.879 1.00 82.66 N ATOM 1162 CA PHE A 160 3.431 10.625 -8.058 1.00 80.18 C ATOM 1163 C PHE A 160 2.588 9.586 -8.809 1.00 87.39 C ATOM 1164 O PHE A 160 2.106 9.841 -9.922 1.00 99.22 O ATOM 1165 CB PHE A 160 2.714 11.062 -6.778 1.00 73.53 C ATOM 1166 CG PHE A 160 3.482 12.076 -5.962 1.00 69.08 C ATOM 1167 CD1 PHE A 160 3.397 13.433 -6.251 1.00 65.98 C ATOM 1168 CD2 PHE A 160 4.293 11.676 -4.908 1.00 66.04 C ATOM 1169 CE1 PHE A 160 4.085 14.375 -5.495 1.00 60.90 C ATOM 1170 CE2 PHE A 160 4.987 12.615 -4.155 1.00 62.97 C ATOM 1171 CZ PHE A 160 4.884 13.962 -4.450 1.00 59.69 C ATOM 1172 N ASP A 161 2.425 8.414 -8.196 1.00 88.41 N ATOM 1173 CA ASP A 161 1.645 7.316 -8.787 1.00 94.83 C ATOM 1174 C ASP A 161 0.121 7.450 -8.560 1.00 93.48 C ATOM 1175 O ASP A 161 -0.668 6.930 -9.358 1.00 95.55 O ATOM 1176 CB ASP A 161 2.171 5.940 -8.305 1.00 97.35 C ATOM 1177 CG ASP A 161 1.622 5.513 -6.933 1.00 95.74 C ATOM 1178 OD1 ASP A 161 1.348 6.385 -6.073 1.00108.28 O ATOM 1179 OD2 ASP A 161 1.486 4.286 -6.713 1.00 90.75 O ATOM 1180 N ASP A 162 -0.284 8.108 -7.469 1.00 86.38 N ATOM 1181 CA ASP A 162 -1.699 8.405 -7.215 1.00 84.91 C ATOM 1182 C ASP A 162 -1.867 9.919 -7.026 1.00 82.42 C ATOM 1183 O ASP A 162 -0.909 10.642 -6.728 1.00 82.98 O ATOM 1184 CB ASP A 162 -2.222 7.598 -6.000 1.00 88.46 C ATOM 1185 CG ASP A 162 -3.774 7.558 -5.901 1.00 91.53 C ATOM 1186 OD1 ASP A 162 -4.445 7.245 -6.909 1.00 99.96 O ATOM 1187 OD2 ASP A 162 -4.330 7.824 -4.803 1.00 81.75 O ATOM 1188 N HIS A 163 -3.088 10.391 -7.259 1.00 83.64 N ATOM 1189 CA HIS A 163 -3.463 11.793 -7.008 1.00 80.08 C ATOM 1190 C HIS A 163 -3.426 12.185 -5.518 1.00 74.44 C ATOM 1191 O HIS A 163 -3.252 13.362 -5.175 1.00 65.98 O ATOM 1192 CB HIS A 163 -4.857 12.103 -7.623 1.00 74.84 C ATOM 1193 CG HIS A 163 -6.002 11.356 -6.999 1.00 71.68 C ATOM 1194 ND1 HIS A 163 -6.678 11.818 -5.888 1.00 75.10 N ATOM 1195 CD2 HIS A 163 -6.635 10.217 -7.369 1.00 75.29 C ATOM 1196 CE1 HIS A 163 -7.655 10.982 -5.580 1.00 72.44 C ATOM 1197 NE2 HIS A 163 -7.648 10.001 -6.461 1.00 73.66 N ATOM 1198 N ASP A 164 -3.606 11.206 -4.634 1.00 69.72 N ATOM 1199 CA ASP A 164 -3.748 11.502 -3.218 1.00 62.01 C ATOM 1200 C ASP A 164 -2.471 12.066 -2.547 1.00 59.61 C ATOM 1201 O ASP A 164 -2.566 12.895 -1.619 1.00 51.75 O ATOM 1202 CB ASP A 164 -4.256 10.280 -2.479 1.00 55.51 C ATOM 1203 CG ASP A 164 -4.575 10.585 -1.045 1.00 61.48 C ATOM 1204 OD1 ASP A 164 -5.368 11.508 -0.779 1.00 64.64 O ATOM 1205 OD2 ASP A 164 -4.001 9.943 -0.146 1.00 66.18 O ATOM 1206 N PRO A 165 -1.284 11.618 -2.985 1.00 53.19 N ATOM 1207 CA PRO A 165 -0.143 12.333 -2.467 1.00 59.85 C ATOM 1208 C PRO A 165 -0.274 13.852 -2.711 1.00 55.81 C ATOM 1209 O PRO A 165 -0.306 14.616 -1.750 1.00 65.40 O ATOM 1210 CB PRO A 165 1.045 11.691 -3.210 1.00 61.35 C ATOM 1211 CG PRO A 165 0.555 10.367 -3.690 1.00 58.50 C ATOM 1212 CD PRO A 165 -0.916 10.268 -3.419 1.00 58.99 C ATOM 1213 N VAL A 166 -0.435 14.254 -3.964 1.00 52.71 N ATOM 1214 CA VAL A 166 -0.638 15.662 -4.314 1.00 51.82 C ATOM 1215 C VAL A 166 -1.729 16.322 -3.493 1.00 55.31 C ATOM 1216 O VAL A 166 -1.472 17.371 -2.822 1.00 50.05 O ATOM 1217 CB VAL A 166 -0.976 15.849 -5.791 1.00 50.27 C ATOM 1218 CG1 VAL A 166 -1.079 17.331 -6.115 1.00 54.71 C ATOM 1219 CG2 VAL A 166 0.068 15.172 -6.659 1.00 50.41 C ATOM 1220 N ASP A 167 -2.926 15.721 -3.532 1.00 51.61 N ATOM 1221 CA ASP A 167 -4.073 16.242 -2.750 1.00 55.94 C ATOM 1222 C ASP A 167 -3.704 16.501 -1.286 1.00 54.70 C ATOM 1223 O ASP A 167 -4.074 17.536 -0.716 1.00 63.94 O ATOM 1224 CB ASP A 167 -5.257 15.291 -2.759 1.00 60.73 C ATOM 1225 CG ASP A 167 -5.838 15.038 -4.158 1.00 72.09 C ATOM 1226 OD1 ASP A 167 -5.290 15.519 -5.199 1.00 73.62 O ATOM 1227 OD2 ASP A 167 -6.868 14.304 -4.192 1.00 77.70 O ATOM 1228 N LYS A 168 -2.958 15.576 -0.679 1.00 49.30 N ATOM 1229 CA LYS A 168 -2.556 15.724 0.716 1.00 48.95 C ATOM 1230 C LYS A 168 -1.601 16.882 0.812 1.00 48.24 C ATOM 1231 O LYS A 168 -1.744 17.731 1.681 1.00 54.22 O ATOM 1232 CB LYS A 168 -1.893 14.432 1.233 1.00 56.61 C ATOM 1233 CG LYS A 168 -1.545 14.336 2.735 1.00 56.80 C ATOM 1234 CD LYS A 168 -0.678 13.072 2.919 1.00 64.92 C ATOM 1235 CE LYS A 168 -0.610 12.515 4.335 1.00 66.78 C ATOM 1236 NZ LYS A 168 -0.282 11.062 4.282 1.00 65.52 N ATOM 1237 N ILE A 169 -0.644 16.909 -0.112 1.00 48.12 N ATOM 1238 CA ILE A 169 0.359 17.970 -0.193 1.00 51.81 C ATOM 1239 C ILE A 169 -0.229 19.392 -0.274 1.00 54.02 C ATOM 1240 O ILE A 169 0.145 20.270 0.522 1.00 52.59 O ATOM 1241 CB ILE A 169 1.349 17.692 -1.359 1.00 49.73 C ATOM 1242 CG1 ILE A 169 2.303 16.583 -0.952 1.00 47.58 C ATOM 1243 CG2 ILE A 169 2.169 18.926 -1.707 1.00 52.47 C ATOM 1244 CD1 ILE A 169 2.996 15.883 -2.100 1.00 47.99 C ATOM 1245 N VAL A 170 -1.159 19.607 -1.207 1.00 56.43 N ATOM 1246 CA VAL A 170 -1.726 20.947 -1.398 1.00 54.19 C ATOM 1247 C VAL A 170 -2.750 21.391 -0.340 1.00 53.51 C ATOM 1248 O VAL A 170 -3.307 22.451 -0.488 1.00 54.75 O ATOM 1249 CB VAL A 170 -2.320 21.143 -2.818 1.00 50.29 C ATOM 1250 CG1 VAL A 170 -1.305 20.763 -3.874 1.00 42.98 C ATOM 1251 CG2 VAL A 170 -3.649 20.403 -2.973 1.00 47.46 C ATOM 1252 N LEU A 171 -2.979 20.623 0.733 1.00 58.67 N ATOM 1253 CA LEU A 171 -3.763 21.130 1.904 1.00 56.70 C ATOM 1254 C LEU A 171 -3.030 22.263 2.609 1.00 53.24 C ATOM 1255 O LEU A 171 -3.575 22.957 3.463 1.00 54.03 O ATOM 1256 CB LEU A 171 -4.048 20.015 2.938 1.00 58.30 C ATOM 1257 CG LEU A 171 -4.882 18.800 2.497 1.00 58.72 C ATOM 1258 CD1 LEU A 171 -4.662 17.655 3.466 1.00 54.85 C ATOM 1259 CD2 LEU A 171 -6.360 19.151 2.379 1.00 57.67 C ATOM 1260 N GLN A 172 -1.765 22.394 2.260 1.00 54.34 N ATOM 1261 CA GLN A 172 -0.843 23.310 2.853 1.00 53.96 C ATOM 1262 C GLN A 172 -0.145 23.972 1.666 1.00 52.70 C ATOM 1263 O GLN A 172 0.440 23.321 0.795 1.00 58.12 O ATOM 1264 CB GLN A 172 0.069 22.482 3.738 1.00 53.00 C ATOM 1265 CG GLN A 172 1.407 23.049 4.101 1.00 57.52 C ATOM 1266 CD GLN A 172 2.333 21.973 4.706 1.00 61.65 C ATOM 1267 OE1 GLN A 172 3.555 22.013 4.515 1.00 53.21 O ATOM 1268 NE2 GLN A 172 1.736 20.971 5.378 1.00 52.88 N ATOM 1269 N LYS A 173 -0.289 25.272 1.590 1.00 51.93 N ATOM 1270 CA LYS A 173 0.311 26.033 0.542 1.00 54.04 C ATOM 1271 C LYS A 173 1.861 26.023 0.678 1.00 51.57 C ATOM 1272 O LYS A 173 2.596 25.813 -0.298 1.00 54.34 O ATOM 1273 CB LYS A 173 -0.271 27.454 0.584 1.00 57.37 C ATOM 1274 CG LYS A 173 0.309 28.396 -0.475 1.00 74.48 C ATOM 1275 CD LYS A 173 1.299 29.408 0.135 1.00 80.74 C ATOM 1276 CE LYS A 173 0.662 30.776 0.421 1.00 78.21 C ATOM 1277 NZ LYS A 173 0.919 31.762 -0.676 1.00 76.26 N ATOM 1278 N TYR A 174 2.355 26.214 1.882 1.00 50.18 N ATOM 1279 CA TYR A 174 3.779 26.328 2.081 1.00 58.83 C ATOM 1280 C TYR A 174 4.342 25.105 2.742 1.00 53.16 C ATOM 1281 O TYR A 174 3.845 24.717 3.776 1.00 55.36 O ATOM 1282 CB TYR A 174 4.063 27.548 2.924 1.00 65.77 C ATOM 1283 CG TYR A 174 4.035 28.873 2.180 1.00 67.71 C ATOM 1284 CD1 TYR A 174 4.803 29.079 1.036 1.00 72.52 C ATOM 1285 CD2 TYR A 174 3.322 29.954 2.682 1.00 78.06 C ATOM 1286 CE1 TYR A 174 4.829 30.304 0.383 1.00 71.40 C ATOM 1287 CE2 TYR A 174 3.351 31.183 2.037 1.00 79.92 C ATOM 1288 CZ TYR A 174 4.097 31.343 0.881 1.00 73.41 C ATOM 1289 OH TYR A 174 4.106 32.557 0.244 1.00 78.57 O ATOM 1290 N HIS A 175 5.365 24.498 2.130 1.00 56.38 N ATOM 1291 CA HIS A 175 6.175 23.399 2.750 1.00 51.72 C ATOM 1292 C HIS A 175 7.593 23.879 2.981 1.00 53.23 C ATOM 1293 O HIS A 175 8.207 24.434 2.048 1.00 52.53 O ATOM 1294 CB HIS A 175 6.248 22.162 1.843 1.00 50.64 C ATOM 1295 CG HIS A 175 4.957 21.432 1.721 1.00 54.41 C ATOM 1296 ND1 HIS A 175 4.670 20.306 2.453 1.00 58.20 N ATOM 1297 CD2 HIS A 175 3.858 21.687 0.974 1.00 60.74 C ATOM 1298 CE1 HIS A 175 3.451 19.892 2.163 1.00 65.07 C ATOM 1299 NE2 HIS A 175 2.930 20.716 1.275 1.00 61.40 N ATOM 1300 N THR A 176 8.114 23.665 4.198 1.00 50.95 N ATOM 1301 CA THR A 176 9.495 24.023 4.545 1.00 50.91 C ATOM 1302 C THR A 176 10.477 22.936 4.019 1.00 55.31 C ATOM 1303 O THR A 176 10.441 21.792 4.490 1.00 59.79 O ATOM 1304 CB THR A 176 9.690 24.148 6.042 1.00 51.32 C ATOM 1305 OG1 THR A 176 8.906 25.219 6.569 1.00 46.64 O ATOM 1306 CG2 THR A 176 11.171 24.366 6.371 1.00 54.16 C ATOM 1307 N ILE A 177 11.315 23.309 3.048 1.00 46.31 N ATOM 1308 CA ILE A 177 12.274 22.420 2.349 1.00 53.43 C ATOM 1309 C ILE A 177 13.614 23.164 2.244 1.00 56.53 C ATOM 1310 O ILE A 177 13.735 24.188 1.547 1.00 51.23 O ATOM 1311 CB ILE A 177 11.837 22.064 0.894 1.00 55.85 C ATOM 1312 CG1 ILE A 177 10.369 21.616 0.839 1.00 58.98 C ATOM 1313 CG2 ILE A 177 12.749 21.004 0.267 1.00 57.72 C ATOM 1314 CD1 ILE A 177 9.891 21.079 -0.519 1.00 60.96 C ATOM 1315 N ASN A 178 14.609 22.670 2.967 1.00 56.20 N ATOM 1316 CA ASN A 178 15.964 23.136 2.806 1.00 55.16 C ATOM 1317 C ASN A 178 16.142 24.604 3.168 1.00 54.78 C ATOM 1318 O ASN A 178 16.657 25.401 2.368 1.00 62.70 O ATOM 1319 CB ASN A 178 16.425 22.877 1.367 1.00 54.96 C ATOM 1320 CG ASN A 178 17.905 23.099 1.202 1.00 63.75 C ATOM 1321 OD1 ASN A 178 18.697 22.581 2.001 1.00 63.80 O ATOM 1322 ND2 ASN A 178 18.295 23.884 0.178 1.00 63.06 N ATOM 1323 N GLY A 179 15.696 24.970 4.359 1.00 49.36 N ATOM 1324 CA GLY A 179 15.731 26.360 4.794 1.00 55.80 C ATOM 1325 C GLY A 179 14.809 27.364 4.084 1.00 61.08 C ATOM 1326 O GLY A 179 14.853 28.564 4.407 1.00 66.18 O ATOM 1327 N HIS A 180 13.944 26.908 3.169 1.00 63.13 N ATOM 1328 CA HIS A 180 13.059 27.821 2.389 1.00 58.82 C ATOM 1329 C HIS A 180 11.593 27.591 2.635 1.00 58.74 C ATOM 1330 O HIS A 180 11.151 26.441 2.675 1.00 52.97 O ATOM 1331 CB HIS A 180 13.218 27.626 0.891 1.00 56.55 C ATOM 1332 CG HIS A 180 14.634 27.618 0.426 1.00 58.84 C ATOM 1333 ND1 HIS A 180 15.523 28.628 0.734 1.00 55.30 N ATOM 1334 CD2 HIS A 180 15.314 26.721 -0.327 1.00 55.00 C ATOM 1335 CE1 HIS A 180 16.700 28.339 0.206 1.00 54.94 C ATOM 1336 NE2 HIS A 180 16.594 27.201 -0.461 1.00 57.92 N ATOM 1337 N ASN A 181 10.842 28.689 2.740 1.00 60.06 N ATOM 1338 CA ASN A 181 9.388 28.648 2.592 1.00 58.99 C ATOM 1339 C ASN A 181 9.022 28.345 1.132 1.00 57.81 C ATOM 1340 O ASN A 181 8.904 29.252 0.309 1.00 77.46 O ATOM 1341 CB ASN A 181 8.740 29.946 3.060 1.00 60.68 C ATOM 1342 CG ASN A 181 7.932 29.767 4.313 1.00 73.40 C ATOM 1343 OD1 ASN A 181 7.099 28.867 4.386 1.00 76.77 O ATOM 1344 ND2 ASN A 181 8.137 30.646 5.302 1.00 81.78 N ATOM 1345 N ALA A 182 8.836 27.065 0.824 1.00 51.30 N ATOM 1346 CA ALA A 182 8.522 26.630 -0.512 1.00 52.34 C ATOM 1347 C ALA A 182 7.002 26.510 -0.757 1.00 54.33 C ATOM 1348 O ALA A 182 6.253 26.138 0.147 1.00 65.61 O ATOM 1349 CB ALA A 182 9.231 25.333 -0.812 1.00 49.87 C ATOM 1350 N GLU A 183 6.571 26.825 -1.982 1.00 48.60 N ATOM 1351 CA GLU A 183 5.140 26.960 -2.323 1.00 51.37 C ATOM 1352 C GLU A 183 4.787 25.795 -3.206 1.00 48.45 C ATOM 1353 O GLU A 183 5.538 25.460 -4.155 1.00 49.66 O ATOM 1354 CB GLU A 183 4.846 28.295 -3.049 1.00 56.42 C ATOM 1355 CG GLU A 183 3.379 28.481 -3.467 1.00 66.25 C ATOM 1356 CD GLU A 183 2.990 29.900 -3.898 1.00 68.19 C ATOM 1357 OE1 GLU A 183 3.644 30.881 -3.489 1.00 60.40 O ATOM 1358 OE2 GLU A 183 1.996 30.023 -4.650 1.00 74.38 O ATOM 1359 N VAL A 184 3.676 25.138 -2.908 1.00 44.89 N ATOM 1360 CA VAL A 184 3.227 24.077 -3.825 1.00 50.03 C ATOM 1361 C VAL A 184 1.890 24.356 -4.489 1.00 47.40 C ATOM 1362 O VAL A 184 1.023 24.986 -3.902 1.00 46.92 O ATOM 1363 CB VAL A 184 3.166 22.669 -3.172 1.00 51.24 C ATOM 1364 CG1 VAL A 184 4.576 22.183 -2.831 1.00 51.80 C ATOM 1365 CG2 VAL A 184 2.201 22.642 -1.986 1.00 50.06 C ATOM 1366 N ARG A 185 1.744 23.785 -5.691 1.00 53.68 N ATOM 1367 CA ARG A 185 0.600 23.974 -6.567 1.00 54.17 C ATOM 1368 C ARG A 185 0.468 22.739 -7.433 1.00 57.34 C ATOM 1369 O ARG A 185 1.488 22.238 -7.921 1.00 53.94 O ATOM 1370 CB ARG A 185 0.868 25.132 -7.526 1.00 52.38 C ATOM 1371 CG ARG A 185 1.169 26.475 -6.893 1.00 53.63 C ATOM 1372 CD ARG A 185 1.870 27.340 -7.933 1.00 55.62 C ATOM 1373 NE ARG A 185 2.261 28.636 -7.397 1.00 58.15 N ATOM 1374 CZ ARG A 185 2.983 29.544 -8.056 1.00 63.61 C ATOM 1375 NH1 ARG A 185 3.396 29.302 -9.291 1.00 56.96 N ATOM 1376 NH2 ARG A 185 3.299 30.708 -7.468 1.00 66.25 N ATOM 1377 N ALYS A 186 -0.764 22.255 -7.628 0.50 60.00 N ATOM 1378 N BLYS A 186 -0.767 22.257 -7.626 0.50 58.24 N ATOM 1379 CA ALYS A 186 -1.052 21.217 -8.620 0.50 60.49 C ATOM 1380 CA BLYS A 186 -1.069 21.214 -8.613 0.50 57.68 C ATOM 1381 C ALYS A 186 -0.577 21.722 -9.963 0.50 65.93 C ATOM 1382 C BLYS A 186 -0.587 21.716 -9.962 0.50 64.26 C ATOM 1383 O ALYS A 186 -0.841 22.874 -10.322 0.50 71.47 O ATOM 1384 O BLYS A 186 -0.856 22.867 -10.323 0.50 70.08 O ATOM 1385 CB ALYS A 186 -2.545 20.940 -8.697 0.50 61.57 C ATOM 1386 CB BLYS A 186 -2.572 20.943 -8.687 0.50 56.72 C ATOM 1387 CG ALYS A 186 -3.120 20.219 -7.488 0.50 63.75 C ATOM 1388 CG BLYS A 186 -3.251 20.550 -7.372 0.50 56.27 C ATOM 1389 CD ALYS A 186 -4.626 20.048 -7.607 0.50 65.63 C ATOM 1390 CD BLYS A 186 -4.593 19.862 -7.620 0.50 56.56 C ATOM 1391 CE ALYS A 186 -5.147 18.974 -6.665 0.50 70.50 C ATOM 1392 CE BLYS A 186 -5.074 19.043 -6.420 0.50 59.30 C ATOM 1393 NZ ALYS A 186 -6.631 19.017 -6.527 0.50 70.23 N ATOM 1394 NZ BLYS A 186 -6.150 19.667 -5.585 0.50 56.87 N ATOM 1395 N ALA A 187 0.154 20.883 -10.690 1.00 68.26 N ATOM 1396 CA ALA A 187 0.706 21.287 -11.982 1.00 67.37 C ATOM 1397 C ALA A 187 -0.438 21.361 -12.979 1.00 74.33 C ATOM 1398 O ALA A 187 -1.253 20.438 -13.075 1.00 66.37 O ATOM 1399 CB ALA A 187 1.758 20.315 -12.465 1.00 68.04 C ATOM 1400 N LEU A 188 -0.523 22.503 -13.651 1.00 79.59 N ATOM 1401 CA LEU A 188 -1.475 22.726 -14.717 1.00 80.12 C ATOM 1402 C LEU A 188 -0.705 22.621 -16.027 1.00 83.42 C ATOM 1403 O LEU A 188 0.522 22.829 -16.049 1.00 76.27 O ATOM 1404 CB LEU A 188 -2.118 24.115 -14.562 1.00 84.47 C ATOM 1405 CG LEU A 188 -2.716 24.486 -13.185 1.00 83.75 C ATOM 1406 CD1 LEU A 188 -2.905 25.997 -13.091 1.00 82.97 C ATOM 1407 CD2 LEU A 188 -4.019 23.746 -12.858 1.00 74.47 C ATOM 1408 N SER A 189 -1.428 22.294 -17.104 1.00 92.84 N ATOM 1409 CA SER A 189 -0.863 22.181 -18.469 1.00 96.76 C ATOM 1410 C SER A 189 -0.160 23.491 -18.933 1.00 95.89 C ATOM 1411 O SER A 189 0.775 23.941 -18.279 1.00 95.94 O ATOM 1412 CB SER A 189 -1.963 21.726 -19.448 1.00 92.35 C ATOM 1413 OG SER A 189 -2.853 22.789 -19.769 1.00 95.71 O ATOM 1414 N ARG A 190 -0.548 24.057 -20.077 1.00105.61 N ATOM 1415 CA ARG A 190 -0.229 25.452 -20.411 1.00102.53 C ATOM 1416 C ARG A 190 -1.416 26.024 -21.197 1.00 89.88 C ATOM 1417 O ARG A 190 -1.295 26.183 -22.402 1.00 88.39 O ATOM 1418 CB ARG A 190 1.064 25.590 -21.248 1.00102.13 C ATOM 1419 CG ARG A 190 2.337 24.960 -20.686 1.00108.27 C ATOM 1420 CD ARG A 190 2.501 23.518 -21.166 1.00114.13 C ATOM 1421 NE ARG A 190 3.732 22.859 -20.716 1.00119.20 N ATOM 1422 CZ ARG A 190 4.962 23.090 -21.189 1.00120.33 C ATOM 1423 NH1 ARG A 190 5.186 24.013 -22.130 1.00120.89 N ATOM 1424 NH2 ARG A 190 5.995 22.398 -20.702 1.00113.86 N ATOM 1425 N GLN A 191 -2.564 26.336 -20.575 1.00 95.72 N ATOM 1426 CA GLN A 191 -2.829 26.303 -19.124 1.00 91.37 C ATOM 1427 C GLN A 191 -4.199 25.671 -18.879 1.00 88.73 C ATOM 1428 O GLN A 191 -4.723 25.681 -17.762 1.00 89.54 O ATOM 1429 CB GLN A 191 -2.799 27.731 -18.554 1.00 89.36 C ATOM 1430 CG GLN A 191 -1.396 28.339 -18.442 1.00 89.19 C ATOM 1431 CD GLN A 191 -1.308 29.800 -18.884 1.00 91.35 C ATOM 1432 OE1 GLN A 191 -0.815 30.642 -18.134 1.00 74.95 O ATOM 1433 NE2 GLN A 191 -1.763 30.103 -20.117 1.00 89.80 N TER 1434 GLN A 191 ATOM 1435 O5' A B 1 -18.723 19.445 -5.722 1.00 68.11 O ATOM 1436 C5' A B 1 -19.717 20.462 -5.528 1.00 74.41 C ATOM 1437 C4' A B 1 -19.547 21.128 -4.180 1.00 71.52 C ATOM 1438 O4' A B 1 -18.673 20.339 -3.331 1.00 68.36 O ATOM 1439 C3' A B 1 -18.888 22.507 -4.210 1.00 66.34 C ATOM 1440 O3' A B 1 -19.088 23.157 -2.975 1.00 63.14 O ATOM 1441 C2' A B 1 -17.418 22.143 -4.203 1.00 67.46 C ATOM 1442 O2' A B 1 -16.538 23.149 -3.748 1.00 71.28 O ATOM 1443 C1' A B 1 -17.431 21.010 -3.186 1.00 66.81 C ATOM 1444 N9 A B 1 -16.356 20.056 -3.404 1.00 70.26 N ATOM 1445 C8 A B 1 -16.102 19.211 -4.461 1.00 68.17 C ATOM 1446 N7 A B 1 -15.025 18.483 -4.308 1.00 63.86 N ATOM 1447 C5 A B 1 -14.533 18.878 -3.071 1.00 60.52 C ATOM 1448 C6 A B 1 -13.414 18.480 -2.331 1.00 53.42 C ATOM 1449 N6 A B 1 -12.541 17.557 -2.744 1.00 53.47 N ATOM 1450 N1 A B 1 -13.201 19.089 -1.145 1.00 59.09 N ATOM 1451 C2 A B 1 -14.083 20.005 -0.722 1.00 57.54 C ATOM 1452 N3 A B 1 -15.170 20.461 -1.325 1.00 60.70 N ATOM 1453 C4 A B 1 -15.338 19.853 -2.511 1.00 62.96 C ATOM 1454 P G B 2 -20.409 23.929 -2.687 1.00 59.03 P ATOM 1455 OP1 G B 2 -21.439 23.538 -3.682 1.00 61.86 O ATOM 1456 OP2 G B 2 -20.060 25.335 -2.487 1.00 68.24 O ATOM 1457 O5' G B 2 -20.914 23.246 -1.356 1.00 55.45 O ATOM 1458 C5' G B 2 -19.991 22.777 -0.389 1.00 57.78 C ATOM 1459 C4' G B 2 -20.695 22.796 0.932 1.00 62.91 C ATOM 1460 O4' G B 2 -19.912 22.058 1.896 1.00 62.29 O ATOM 1461 C3' G B 2 -20.905 24.182 1.527 1.00 63.37 C ATOM 1462 O3' G B 2 -22.036 24.170 2.378 1.00 72.90 O ATOM 1463 C2' G B 2 -19.677 24.355 2.401 1.00 65.25 C ATOM 1464 O2' G B 2 -19.968 25.204 3.489 1.00 61.53 O ATOM 1465 C1' G B 2 -19.478 22.927 2.911 1.00 64.81 C ATOM 1466 N9 G B 2 -18.133 22.528 3.323 1.00 57.23 N ATOM 1467 C8 G B 2 -17.816 21.974 4.539 1.00 58.86 C ATOM 1468 N7 G B 2 -16.539 21.748 4.682 1.00 56.45 N ATOM 1469 C5 G B 2 -15.980 22.156 3.481 1.00 51.41 C ATOM 1470 C6 G B 2 -14.636 22.125 3.046 1.00 48.46 C ATOM 1471 O6 G B 2 -13.645 21.711 3.653 1.00 60.20 O ATOM 1472 N1 G B 2 -14.497 22.660 1.770 1.00 47.48 N ATOM 1473 C2 G B 2 -15.527 23.150 1.003 1.00 48.23 C ATOM 1474 N2 G B 2 -15.186 23.614 -0.214 1.00 46.50 N ATOM 1475 N3 G B 2 -16.792 23.187 1.402 1.00 46.12 N ATOM 1476 C4 G B 2 -16.946 22.661 2.636 1.00 48.34 C ATOM 1477 P G B 3 -23.323 25.056 2.043 1.00 66.59 P ATOM 1478 OP1 G B 3 -23.855 24.611 0.738 1.00 69.67 O ATOM 1479 OP2 G B 3 -22.949 26.470 2.218 1.00 75.25 O ATOM 1480 O5' G B 3 -24.312 24.601 3.198 1.00 59.84 O ATOM 1481 C5' G B 3 -24.052 24.979 4.559 1.00 65.82 C ATOM 1482 C4' G B 3 -24.784 24.050 5.493 1.00 67.81 C ATOM 1483 O4' G B 3 -24.511 22.669 5.130 1.00 63.40 O ATOM 1484 C3' G B 3 -24.393 24.146 6.955 1.00 67.98 C ATOM 1485 O3' G B 3 -25.133 25.142 7.632 1.00 77.68 O ATOM 1486 C2' G B 3 -24.729 22.754 7.448 1.00 66.52 C ATOM 1487 O2' G B 3 -26.110 22.528 7.514 1.00 67.62 O ATOM 1488 C1' G B 3 -24.193 21.922 6.295 1.00 64.02 C ATOM 1489 N9 G B 3 -22.744 21.702 6.329 1.00 59.78 N ATOM 1490 C8 G B 3 -21.817 22.176 5.433 1.00 54.55 C ATOM 1491 N7 G B 3 -20.601 21.783 5.699 1.00 53.30 N ATOM 1492 C5 G B 3 -20.729 21.011 6.843 1.00 50.65 C ATOM 1493 C6 G B 3 -19.750 20.309 7.592 1.00 58.80 C ATOM 1494 O6 G B 3 -18.528 20.238 7.392 1.00 60.82 O ATOM 1495 N1 G B 3 -20.316 19.641 8.675 1.00 57.12 N ATOM 1496 C2 G B 3 -21.653 19.654 9.001 1.00 51.25 C ATOM 1497 N2 G B 3 -22.010 18.950 10.091 1.00 49.72 N ATOM 1498 N3 G B 3 -22.577 20.280 8.293 1.00 46.71 N ATOM 1499 C4 G B 3 -22.048 20.940 7.240 1.00 52.30 C ATOM 1500 P G B 4 -24.374 26.277 8.459 1.00 79.16 P ATOM 1501 OP1 G B 4 -25.405 27.216 8.963 1.00 90.68 O ATOM 1502 OP2 G B 4 -23.293 26.823 7.597 1.00 69.23 O ATOM 1503 O5' G B 4 -23.838 25.467 9.722 1.00 67.40 O ATOM 1504 C5' G B 4 -24.747 25.015 10.749 1.00 73.46 C ATOM 1505 C4' G B 4 -24.081 23.995 11.639 1.00 74.19 C ATOM 1506 O4' G B 4 -23.550 22.932 10.803 1.00 78.51 O ATOM 1507 C3' G B 4 -22.885 24.488 12.453 1.00 75.11 C ATOM 1508 O3' G B 4 -23.221 25.062 13.714 1.00 74.05 O ATOM 1509 C2' G B 4 -22.079 23.208 12.651 1.00 74.28 C ATOM 1510 O2' G B 4 -22.407 22.430 13.791 1.00 73.41 O ATOM 1511 C1' G B 4 -22.291 22.512 11.301 1.00 70.59 C ATOM 1512 N9 G B 4 -21.253 22.886 10.343 1.00 61.63 N ATOM 1513 C8 G B 4 -21.338 23.744 9.270 1.00 56.94 C ATOM 1514 N7 G B 4 -20.193 23.924 8.666 1.00 50.39 N ATOM 1515 C5 G B 4 -19.292 23.171 9.407 1.00 48.70 C ATOM 1516 C6 G B 4 -17.909 22.932 9.204 1.00 50.53 C ATOM 1517 O6 G B 4 -17.171 23.378 8.316 1.00 52.46 O ATOM 1518 N1 G B 4 -17.388 22.082 10.177 1.00 46.85 N ATOM 1519 C2 G B 4 -18.110 21.522 11.207 1.00 49.78 C ATOM 1520 N2 G B 4 -17.430 20.729 12.048 1.00 48.73 N ATOM 1521 N3 G B 4 -19.403 21.720 11.395 1.00 45.86 N ATOM 1522 C4 G B 4 -19.931 22.527 10.449 1.00 54.56 C ATOM 1523 P A B 5 -22.487 26.401 14.244 1.00 74.57 P ATOM 1524 OP1 A B 5 -23.112 26.758 15.541 1.00 84.07 O ATOM 1525 OP2 A B 5 -22.424 27.407 13.132 1.00 54.30 O ATOM 1526 O5' A B 5 -21.008 25.928 14.589 1.00 66.31 O ATOM 1527 C5' A B 5 -20.737 24.813 15.453 1.00 70.03 C ATOM 1528 C4' A B 5 -19.301 24.367 15.271 1.00 74.15 C ATOM 1529 O4' A B 5 -19.079 23.903 13.909 1.00 69.38 O ATOM 1530 C3' A B 5 -18.239 25.444 15.474 1.00 73.83 C ATOM 1531 O3' A B 5 -17.972 25.563 16.869 1.00 70.32 O ATOM 1532 C2' A B 5 -17.061 24.857 14.702 1.00 73.65 C ATOM 1533 O2' A B 5 -16.369 23.878 15.455 1.00 74.97 O ATOM 1534 C1' A B 5 -17.766 24.233 13.493 1.00 64.51 C ATOM 1535 N9 A B 5 -17.848 25.106 12.314 1.00 58.69 N ATOM 1536 C8 A B 5 -18.932 25.801 11.834 1.00 60.90 C ATOM 1537 N7 A B 5 -18.682 26.480 10.738 1.00 62.46 N ATOM 1538 C5 A B 5 -17.344 26.217 10.480 1.00 55.18 C ATOM 1539 C6 A B 5 -16.475 26.648 9.460 1.00 60.64 C ATOM 1540 N6 A B 5 -16.843 27.470 8.472 1.00 66.12 N ATOM 1541 N1 A B 5 -15.193 26.217 9.502 1.00 50.86 N ATOM 1542 C2 A B 5 -14.830 25.381 10.486 1.00 54.55 C ATOM 1543 N3 A B 5 -15.557 24.900 11.496 1.00 56.86 N ATOM 1544 C4 A B 5 -16.815 25.376 11.445 1.00 55.43 C ATOM 1545 P C B 6 -17.716 26.991 17.565 1.00 77.59 P ATOM 1546 OP1 C B 6 -17.687 26.755 19.031 1.00 80.80 O ATOM 1547 OP2 C B 6 -18.653 27.987 16.979 1.00 62.80 O ATOM 1548 O5' C B 6 -16.250 27.428 17.105 1.00 68.57 O ATOM 1549 C5' C B 6 -15.092 26.590 17.283 1.00 74.26 C ATOM 1550 C4' C B 6 -13.980 27.058 16.368 1.00 76.92 C ATOM 1551 O4' C B 6 -14.398 26.966 14.984 1.00 75.16 O ATOM 1552 C3' C B 6 -13.551 28.501 16.605 1.00 81.42 C ATOM 1553 O3' C B 6 -12.170 28.574 16.907 1.00 89.41 O ATOM 1554 C2' C B 6 -13.996 29.260 15.358 1.00 77.91 C ATOM 1555 O2' C B 6 -13.165 30.346 14.990 1.00 72.80 O ATOM 1556 C1' C B 6 -14.068 28.157 14.302 1.00 78.16 C ATOM 1557 N1 C B 6 -15.132 28.468 13.317 1.00 76.18 N ATOM 1558 C2 C B 6 -14.774 29.019 12.077 1.00 71.48 C ATOM 1559 O2 C B 6 -13.571 29.154 11.803 1.00 70.81 O ATOM 1560 N3 C B 6 -15.747 29.372 11.204 1.00 68.64 N ATOM 1561 C4 C B 6 -17.032 29.217 11.538 1.00 74.12 C ATOM 1562 N4 C B 6 -17.958 29.558 10.637 1.00 70.42 N ATOM 1563 C5 C B 6 -17.424 28.670 12.796 1.00 73.55 C ATOM 1564 C6 C B 6 -16.452 28.330 13.653 1.00 76.38 C ATOM 1565 P U B 7 -11.724 28.910 18.402 1.00 91.01 P ATOM 1566 OP1 U B 7 -10.972 27.748 18.941 1.00 82.99 O ATOM 1567 OP2 U B 7 -12.895 29.484 19.150 1.00 72.62 O ATOM 1568 O5' U B 7 -10.652 30.059 18.198 1.00 81.98 O ATOM 1569 C5' U B 7 -10.743 31.077 17.195 1.00 79.73 C ATOM 1570 C4' U B 7 -9.452 31.845 17.258 1.00 82.49 C ATOM 1571 O4' U B 7 -9.197 32.161 18.661 1.00 77.03 O ATOM 1572 C3' U B 7 -8.235 31.057 16.763 1.00 74.64 C ATOM 1573 O3' U B 7 -7.355 31.834 15.954 1.00 79.87 O ATOM 1574 C2' U B 7 -7.593 30.566 18.057 1.00 74.24 C ATOM 1575 O2' U B 7 -6.211 30.270 17.992 1.00 72.51 O ATOM 1576 C1' U B 7 -7.901 31.725 19.004 1.00 77.97 C ATOM 1577 N1 U B 7 -7.858 31.349 20.430 1.00 68.11 N ATOM 1578 C2 U B 7 -6.752 31.759 21.152 1.00 66.19 C ATOM 1579 O2 U B 7 -5.869 32.458 20.677 1.00 61.55 O ATOM 1580 N3 U B 7 -6.724 31.331 22.456 1.00 67.35 N ATOM 1581 C4 U B 7 -7.661 30.553 23.101 1.00 72.71 C ATOM 1582 O4 U B 7 -7.494 30.262 24.288 1.00 83.84 O ATOM 1583 C5 U B 7 -8.771 30.162 22.287 1.00 68.35 C ATOM 1584 C6 U B 7 -8.823 30.551 21.005 1.00 67.17 C ATOM 1585 P A B 8 -6.234 31.122 15.028 1.00 77.46 P ATOM 1586 OP1 A B 8 -6.696 29.759 14.698 1.00 86.14 O ATOM 1587 OP2 A B 8 -4.925 31.292 15.675 1.00 83.12 O ATOM 1588 O5' A B 8 -6.221 32.024 13.715 1.00 82.34 O ATOM 1589 C5' A B 8 -7.427 32.559 13.142 1.00 80.73 C ATOM 1590 C4' A B 8 -7.070 33.601 12.107 1.00 85.18 C ATOM 1591 O4' A B 8 -6.401 34.695 12.773 1.00 84.39 O ATOM 1592 C3' A B 8 -6.163 33.135 10.959 1.00 78.46 C ATOM 1593 O3' A B 8 -6.556 33.527 9.649 1.00 82.26 O ATOM 1594 C2' A B 8 -4.838 33.853 11.190 1.00 76.75 C ATOM 1595 O2' A B 8 -4.279 34.266 9.950 1.00 73.61 O ATOM 1596 C1' A B 8 -5.232 35.039 12.077 1.00 72.55 C ATOM 1597 N9 A B 8 -4.198 35.329 13.064 1.00 62.24 N ATOM 1598 C8 A B 8 -3.767 34.513 14.083 1.00 67.46 C ATOM 1599 N7 A B 8 -2.760 35.005 14.762 1.00 65.25 N ATOM 1600 C5 A B 8 -2.504 36.221 14.145 1.00 64.70 C ATOM 1601 C6 A B 8 -1.564 37.233 14.401 1.00 64.06 C ATOM 1602 N6 A B 8 -0.667 37.178 15.388 1.00 69.53 N ATOM 1603 N1 A B 8 -1.573 38.317 13.595 1.00 68.27 N ATOM 1604 C2 A B 8 -2.472 38.372 12.604 1.00 65.90 C ATOM 1605 N3 A B 8 -3.403 37.485 12.264 1.00 60.35 N ATOM 1606 C4 A B 8 -3.373 36.425 13.088 1.00 61.06 C ATOM 1607 P G B 9 -7.948 33.059 9.046 1.00 85.19 P ATOM 1608 OP1 G B 9 -8.609 32.154 10.016 1.00 74.72 O ATOM 1609 OP2 G B 9 -7.703 32.623 7.657 1.00 96.45 O ATOM 1610 O5' G B 9 -8.811 34.393 9.034 1.00 88.27 O ATOM 1611 C5' G B 9 -8.177 35.663 9.225 1.00 90.96 C ATOM 1612 C4' G B 9 -9.205 36.759 9.179 1.00 89.97 C ATOM 1613 O4' G B 9 -8.674 37.934 9.831 1.00 98.95 O ATOM 1614 C3' G B 9 -9.586 37.234 7.791 1.00 95.19 C ATOM 1615 O3' G B 9 -10.895 37.775 7.861 1.00 97.68 O ATOM 1616 C2' G B 9 -8.495 38.253 7.479 1.00 99.52 C ATOM 1617 O2' G B 9 -8.875 39.230 6.530 1.00106.34 O ATOM 1618 C1' G B 9 -8.220 38.853 8.861 1.00100.60 C ATOM 1619 N9 G B 9 -6.807 39.115 9.111 1.00102.45 N ATOM 1620 C8 G B 9 -5.814 38.206 9.394 1.00107.88 C ATOM 1621 N7 G B 9 -4.643 38.761 9.551 1.00103.04 N ATOM 1622 C5 G B 9 -4.878 40.115 9.366 1.00106.63 C ATOM 1623 C6 G B 9 -3.987 41.217 9.420 1.00116.29 C ATOM 1624 O6 G B 9 -2.772 41.216 9.651 1.00117.60 O ATOM 1625 N1 G B 9 -4.645 42.418 9.166 1.00124.06 N ATOM 1626 C2 G B 9 -5.987 42.541 8.891 1.00130.66 C ATOM 1627 N2 G B 9 -6.440 43.783 8.662 1.00145.25 N ATOM 1628 N3 G B 9 -6.828 41.522 8.851 1.00117.74 N ATOM 1629 C4 G B 9 -6.210 40.349 9.097 1.00105.86 C ATOM 1630 P C B 10 -11.945 37.307 6.795 1.00 76.88 P ATOM 1631 OP1 C B 10 -13.264 37.235 7.435 1.00 78.59 O ATOM 1632 OP2 C B 10 -11.412 36.117 6.137 1.00 75.20 O ATOM 1633 O5' C B 10 -11.973 38.540 5.797 1.00 78.76 O TER 1634 C B 10 HETATM 1635 O HOH A 201 15.508 25.996 -9.582 1.00 55.41 O HETATM 1636 O HOH A 202 -23.693 5.649 -1.071 1.00 46.81 O HETATM 1637 O HOH A 203 -26.813 10.843 0.378 1.00 49.07 O HETATM 1638 O HOH A 204 -5.656 16.284 15.609 1.00 58.20 O HETATM 1639 O HOH A 205 -29.857 4.679 -4.303 1.00 49.48 O HETATM 1640 O HOH A 206 13.415 15.786 3.424 1.00 52.46 O MASTER 316 0 0 7 11 0 0 6 1613 2 0 16 END
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Related entries of code: 5wwe
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
5en1
RCSB PDB
PDBbind
184aa, >5EN1_1|Chain... *
5ho4
RCSB PDB
PDBbind
179aa, >5HO4_1|Chain... at 100%
5wwf
RCSB PDB
PDBbind
184aa, >5WWF_1|Chains... at 100%
5wwg
RCSB PDB
PDBbind
184aa, >5WWG_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
5wwe
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNPA2B1
Ligand Name
10-bp RNA mutant A1G
EC.Number
E.C.-.-.-.-
Resolution
2.4(Å)
Affinity (Kd/Ki/IC50)
Kd=534.8nM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) Nat Commun Vol. 9: pp. 420-420
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P22626
Entrez Gene ID
NCBI Entrez Gene ID:
3181
ASD
Information of known allosteric effects of PDB entries
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