Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION 28-OCT-08 3F1P TITLE CRYSTAL STRUCTURE OF A HIGH AFFINITY HETERODIMER OF HIF2 ALPHA AND TITLE 2 ARNT C-TERMINAL PAS DOMAINS COMPND MOL_ID: 1; COMPND 2 MOLECULE: ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: HIF2 ALPHA C-TERMINAL PAS DOMAIN; COMPND 5 SYNONYM: EPAS-1, MEMBER OF PAS PROTEIN 2, BASIC-HELIX-LOOP-HELIX-PAS COMPND 6 PROTEIN MOP2, HYPOXIA-INDUCIBLE FACTOR 2 ALPHA, HIF-2 ALPHA, HIF2 COMPND 7 ALPHA, HIF-1 ALPHA-LIKE FACTOR, HLF; COMPND 8 ENGINEERED: YES; COMPND 9 MUTATION: YES; COMPND 10 MOL_ID: 2; COMPND 11 MOLECULE: ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; COMPND 12 CHAIN: B; COMPND 13 FRAGMENT: ARNT C-TERMINAL PAS DOMAIN; COMPND 14 SYNONYM: ARNT PROTEIN, DIOXIN RECEPTOR, NUCLEAR TRANSLOCATOR, COMPND 15 HYPOXIA-INDUCIBLE FACTOR 1 BETA, HIF-1 BETA; COMPND 16 ENGINEERED: YES; COMPND 17 MUTATION: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: EPAS1, HIF2A, HYPOXIA INDUCIBLE FACTOR 2 ALPHA, MOP2; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PHIS-GB1-PARALLEL; SOURCE 10 MOL_ID: 2; SOURCE 11 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 12 ORGANISM_COMMON: HUMAN; SOURCE 13 ORGANISM_TAXID: 9606; SOURCE 14 GENE: ARNT, ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; SOURCE 15 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 16 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 17 EXPRESSION_SYSTEM_STRAIN: BL21; SOURCE 18 EXPRESSION_SYSTEM_VECTOR_TYPE: PHIS-PARALLEL KEYWDS PAS DOMAIN, HETERODIMER, INTERNAL CAVITY, ACTIVATOR, ANGIOGENESIS, KEYWDS 2 CONGENITAL ERYTHROCYTOSIS, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, KEYWDS 3 DISEASE MUTATION, DNA-BINDING, HYDROXYLATION, NUCLEUS, KEYWDS 4 PHOSPHOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL KEYWDS 5 CONJUGATION, ALTERNATIVE SPLICING, POLYMORPHISM EXPDTA X-RAY DIFFRACTION AUTHOR T.H.SCHEUERMANN,D.R.TOMCHICK,M.MACHIUS,Y.GUO,R.K.BRUICK,K.H.GARDNER REVDAT 4 25-OCT-17 3F1P 1 REMARK REVDAT 3 17-MAR-09 3F1P 1 AUTHOR REVDAT 2 17-FEB-09 3F1P 1 JRNL REVDAT 1 20-JAN-09 3F1P 0 JRNL AUTH T.H.SCHEUERMANN,D.R.TOMCHICK,M.MACHIUS,Y.GUO,R.K.BRUICK, JRNL AUTH 2 K.H.GARDNER JRNL TITL ARTIFICIAL LIGAND BINDING WITHIN THE HIF2ALPHA PAS-B DOMAIN JRNL TITL 2 OF THE HIF2 TRANSCRIPTION FACTOR. JRNL REF PROC.NATL.ACAD.SCI.USA V. 106 450 2009 JRNL REFN ISSN 0027-8424 JRNL PMID 19129502 JRNL DOI 10.1073/PNAS.0808092106 REMARK 2 REMARK 2 RESOLUTION. 1.17 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX 1.3 REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.17 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 26.93 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.330 REMARK 3 COMPLETENESS FOR RANGE (%) : 95.1 REMARK 3 NUMBER OF REFLECTIONS : 75655 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.141 REMARK 3 R VALUE (WORKING SET) : 0.141 REMARK 3 FREE R VALUE : 0.167 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 2.010 REMARK 3 FREE R VALUE TEST SET COUNT : 1523 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 26.9336 - 2.6014 1.00 7135 180 0.1599 0.1692 REMARK 3 2 2.6014 - 2.0650 1.00 7104 141 0.1340 0.1539 REMARK 3 3 2.0650 - 1.8041 0.99 7056 138 0.1216 0.1787 REMARK 3 4 1.8041 - 1.6391 0.98 6935 154 0.1127 0.1381 REMARK 3 5 1.6391 - 1.5217 0.98 6940 118 0.1094 0.1545 REMARK 3 6 1.5217 - 1.4320 0.97 6884 160 0.1189 0.1358 REMARK 3 7 1.4320 - 1.3602 0.97 6814 139 0.1232 0.1421 REMARK 3 8 1.3602 - 1.3010 0.97 6881 126 0.1302 0.1748 REMARK 3 9 1.3010 - 1.2509 0.96 6810 118 0.1437 0.1989 REMARK 3 10 1.2509 - 1.2078 0.94 6585 145 0.1685 0.2061 REMARK 3 11 1.2078 - 1.1700 0.70 4988 104 0.1796 0.2196 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : 0.43 REMARK 3 B_SOL : 64.81 REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.120 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : NULL REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 11.46 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 18.90 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 1.99210 REMARK 3 B22 (A**2) : -1.66780 REMARK 3 B33 (A**2) : -0.32440 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.75630 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.015 NULL REMARK 3 ANGLE : NULL NULL REMARK 3 CHIRALITY : NULL NULL REMARK 3 PLANARITY : NULL NULL REMARK 3 DIHEDRAL : 16.020 NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 3F1P COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 31-OCT-08. REMARK 100 THE DEPOSITION ID IS D_1000050035. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 15-DEC-07 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 6.5 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : APS REMARK 200 BEAMLINE : 19-ID REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.97904 REMARK 200 MONOCHROMATOR : CUSTOM REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 315 REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-3000 REMARK 200 DATA SCALING SOFTWARE : HKL-3000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 76140 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.170 REMARK 200 RESOLUTION RANGE LOW (A) : 26.930 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 95.8 REMARK 200 DATA REDUNDANCY : 4.700 REMARK 200 R MERGE (I) : 0.06800 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 31.2000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.17 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.18 REMARK 200 COMPLETENESS FOR SHELL (%) : 64.3 REMARK 200 DATA REDUNDANCY IN SHELL : 1.30 REMARK 200 R MERGE FOR SHELL (I) : 0.36900 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 2.100 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: PDB ENTRY 2B02 REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 43.21 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.17 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 30% PEG3350, 0.1M BISTRIS, 0.05M TRIS, REMARK 280 0.017M NACL, 0.005M DTT, PH 6.5, VAPOR DIFFUSION COMBINED WITH REMARK 280 MICROSEEDING, TEMPERATURE 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y,-Z REMARK 290 3555 X+1/2,Y+1/2,Z REMARK 290 4555 -X+1/2,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 3 1.000000 0.000000 0.000000 36.95800 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 41.28250 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 36.95800 REMARK 290 SMTRY2 4 0.000000 1.000000 0.000000 41.28250 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 1910 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 11440 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -11.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLY A 234 REMARK 465 GLU A 235 REMARK 465 ASN A 350 REMARK 465 GLY B 350 REMARK 465 GLU B 351 REMARK 465 PHE B 352 REMARK 465 LYS B 353 REMARK 465 GLY B 354 REMARK 465 LEU B 355 REMARK 465 ASN B 356 REMARK 465 SER B 468 REMARK 465 GLN B 469 REMARK 465 GLU B 470 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 HE3 MET A 338 O HOH B 163 1.42 REMARK 500 O HOH B 166 O HOH B 224 2.07 REMARK 500 SD MET A 338 O HOH B 163 2.16 REMARK 500 CE MET A 338 O HOH B 163 2.18 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS REMARK 500 REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC REMARK 500 SYMMETRY ARE IN CLOSE CONTACT. AN ATOM LOCATED WITHIN 0.15 REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375 REMARK 500 INSTEAD OF REMARK 500. ATOMS WITH NON-BLANK ALTERNATE REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS. REMARK 500 REMARK 500 DISTANCE CUTOFF: REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI SSYMOP DISTANCE REMARK 500 N LEU A 332 CD2 LEU A 332 2556 0.20 REMARK 500 CA LEU A 332 CG LEU A 332 2556 0.24 REMARK 500 C LEU A 332 CD1 LEU A 332 2556 0.45 REMARK 500 CD1 LEU A 332 N GLN A 333 2556 0.88 REMARK 500 CD2 LEU A 332 H LEU A 332 2556 0.90 REMARK 500 CG LEU A 332 HA LEU A 332 2556 0.97 REMARK 500 C LEU A 332 CG LEU A 332 2556 1.34 REMARK 500 CA LEU A 332 CD2 LEU A 332 2556 1.38 REMARK 500 C ASN A 331 CD2 LEU A 332 2556 1.49 REMARK 500 O LEU A 332 CD1 LEU A 332 2556 1.52 REMARK 500 CD1 LEU A 332 H GLN A 333 2556 1.53 REMARK 500 CA LEU A 332 CB LEU A 332 2556 1.61 REMARK 500 N LEU A 332 CG LEU A 332 2556 1.68 REMARK 500 CA LEU A 332 CD1 LEU A 332 2556 1.78 REMARK 500 O LEU A 332 CG LEU A 332 2556 2.19 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 ASP A 258 CB - CG - OD1 ANGL. DEV. = -10.0 DEGREES REMARK 500 ASP A 258 CB - CG - OD2 ANGL. DEV. = 6.2 DEGREES REMARK 500 LEU A 332 CA - CB - CG ANGL. DEV. = 24.4 DEGREES REMARK 500 LEU A 332 CB - CG - CD2 ANGL. DEV. = 22.4 DEGREES REMARK 500 ASP B 377 CB - CG - OD1 ANGL. DEV. = 5.5 DEGREES REMARK 500 ASP B 410 CB - CG - OD2 ANGL. DEV. = -9.2 DEGREES REMARK 500 ARG B 430 NE - CZ - NH2 ANGL. DEV. = -3.9 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS REMARK 500 REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES. REMARK 500 MODEL OMEGA REMARK 500 TYR A 327 ASN A 328 149.27 REMARK 500 REMARK 500 REMARK: NULL REMARK 650 REMARK 650 HELIX REMARK 650 DETERMINATION METHOD: AUTHOR DETERMINED REMARK 700 REMARK 700 SHEET REMARK 700 DETERMINATION METHOD: AUTHOR DETERMINED REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 1X0O RELATED DB: PDB REMARK 900 NMR STRUCTURE OF THE ARNT C-TERMINAL PAS-B DOMAIN REMARK 900 RELATED ID: 1P97 RELATED DB: PDB REMARK 900 NMR STRUCTURE OF THE HIF2 ALPHA C-TERMINAL PAS-B DOMAIN REMARK 900 RELATED ID: 2B02 RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF THE ARNT C-TERMINAL PAS-B DOMAIN REMARK 900 RELATED ID: 2A24 RELATED DB: PDB REMARK 900 NMR-GUIDED MODEL OF THE HETERODIMER OF THE WILD-TYPE HIF2 ALPHA AND REMARK 900 ARNT C-TERMINAL PAS DOMAINS REMARK 900 RELATED ID: 3F1N RELATED DB: PDB REMARK 900 RELATED ID: 3F1O RELATED DB: PDB DBREF 3F1P A 239 350 UNP Q99814 EPAS1_HUMAN 239 350 DBREF 3F1P B 356 470 UNP P27540 ARNT_HUMAN 356 470 SEQADV 3F1P GLY A 234 UNP Q99814 EXPRESSION TAG SEQADV 3F1P GLU A 235 UNP Q99814 EXPRESSION TAG SEQADV 3F1P PHE A 236 UNP Q99814 EXPRESSION TAG SEQADV 3F1P LYS A 237 UNP Q99814 EXPRESSION TAG SEQADV 3F1P GLY A 238 UNP Q99814 EXPRESSION TAG SEQADV 3F1P GLU A 247 UNP Q99814 ARG 247 ENGINEERED SEQADV 3F1P GLY B 350 UNP P27540 EXPRESSION TAG SEQADV 3F1P GLU B 351 UNP P27540 EXPRESSION TAG SEQADV 3F1P PHE B 352 UNP P27540 EXPRESSION TAG SEQADV 3F1P LYS B 353 UNP P27540 EXPRESSION TAG SEQADV 3F1P GLY B 354 UNP P27540 EXPRESSION TAG SEQADV 3F1P LEU B 355 UNP P27540 EXPRESSION TAG SEQADV 3F1P ARG B 362 UNP P27540 GLU 362 ENGINEERED SEQRES 1 A 117 GLY GLU PHE LYS GLY LEU ASP SER LYS THR PHE LEU SER SEQRES 2 A 117 GLU HIS SER MET ASP MET LYS PHE THR TYR CYS ASP ASP SEQRES 3 A 117 ARG ILE THR GLU LEU ILE GLY TYR HIS PRO GLU GLU LEU SEQRES 4 A 117 LEU GLY ARG SER ALA TYR GLU PHE TYR HIS ALA LEU ASP SEQRES 5 A 117 SER GLU ASN MET THR LYS SER HIS GLN ASN LEU CYS THR SEQRES 6 A 117 LYS GLY GLN VAL VAL SER GLY GLN TYR ARG MET LEU ALA SEQRES 7 A 117 LYS HIS GLY GLY TYR VAL TRP LEU GLU THR GLN GLY THR SEQRES 8 A 117 VAL ILE TYR ASN PRO ARG ASN LEU GLN PRO GLN CYS ILE SEQRES 9 A 117 MET CYS VAL ASN TYR VAL LEU SER GLU ILE GLU LYS ASN SEQRES 1 B 121 GLY GLU PHE LYS GLY LEU ASN VAL CYS GLN PRO THR ARG SEQRES 2 B 121 PHE ILE SER ARG HIS ASN ILE GLU GLY ILE PHE THR PHE SEQRES 3 B 121 VAL ASP HIS ARG CYS VAL ALA THR VAL GLY TYR GLN PRO SEQRES 4 B 121 GLN GLU LEU LEU GLY LYS ASN ILE VAL GLU PHE CYS HIS SEQRES 5 B 121 PRO GLU ASP GLN GLN LEU LEU ARG ASP SER PHE GLN GLN SEQRES 6 B 121 VAL VAL LYS LEU LYS GLY GLN VAL LEU SER VAL MET PHE SEQRES 7 B 121 ARG PHE ARG SER LYS ASN GLN GLU TRP LEU TRP MET ARG SEQRES 8 B 121 THR SER SER PHE THR PHE GLN ASN PRO TYR SER ASP GLU SEQRES 9 B 121 ILE GLU TYR ILE ILE CYS THR ASN THR ASN VAL LYS ASN SEQRES 10 B 121 SER SER GLN GLU FORMUL 3 HOH *257(H2 O) HELIX 1 1 LEU A 239 SER A 241 5 3 HELIX 2 2 ARG A 260 ILE A 265 1 6 HELIX 3 3 PRO A 269 LEU A 272 1 4 HELIX 4 4 ALA A 277 PHE A 280 5 4 HELIX 5 5 LEU A 284 LYS A 299 1 16 HELIX 6 6 ARG B 379 VAL B 384 1 6 HELIX 7 7 PRO B 388 LEU B 392 1 5 HELIX 8 8 ILE B 396 CYS B 400 5 5 HELIX 9 9 ASP B 404 LYS B 417 1 14 SHEET 1 A 5 PHE A 254 CYS A 257 0 SHEET 2 A 5 THR A 243 HIS A 248 -1 N GLU A 247 O THR A 255 SHEET 3 A 5 CYS A 336 VAL A 343 -1 O CYS A 339 N SER A 246 SHEET 4 A 5 TYR A 316 ILE A 326 -1 N THR A 324 O MET A 338 SHEET 5 A 5 GLN A 301 LEU A 310 -1 N VAL A 302 O LEU A 319 SHEET 1 B 5 PHE A 254 CYS A 257 0 SHEET 2 B 5 THR A 243 HIS A 248 -1 N GLU A 247 O THR A 255 SHEET 3 B 5 CYS A 336 VAL A 343 -1 O CYS A 339 N SER A 246 SHEET 4 B 5 TYR A 316 ILE A 326 -1 N THR A 324 O MET A 338 SHEET 1 C 5 PHE B 373 VAL B 376 0 SHEET 2 C 5 ARG B 362 HIS B 367 -1 N ARG B 366 O THR B 374 SHEET 3 C 5 TYR B 456 ASN B 463 -1 O CYS B 459 N SER B 365 SHEET 4 C 5 TRP B 436 PHE B 446 -1 N PHE B 444 O ILE B 458 SHEET 5 C 5 LEU B 423 ARG B 430 -1 N PHE B 427 O MET B 439 CRYST1 73.916 82.565 41.032 90.00 106.02 90.00 C 1 2 1 4 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.013529 0.000000 0.003884 0.00000 SCALE2 0.000000 0.012112 0.000000 0.00000 SCALE3 0.000000 0.000000 0.025356 0.00000 ATOM 1 N PHE A 236 29.442 -55.509 -2.324 1.00 24.52 N ANISOU 1 N PHE A 236 2241 3850 3225 -292 135 -482 N ATOM 2 CA PHE A 236 28.061 -55.953 -2.192 1.00 20.08 C ANISOU 2 CA PHE A 236 2102 3051 2475 -299 -96 -211 C ATOM 3 C PHE A 236 27.739 -56.448 -0.776 1.00 19.29 C ANISOU 3 C PHE A 236 2347 2940 2042 -59 501 -287 C ATOM 4 O PHE A 236 28.456 -57.260 -0.208 1.00 23.89 O ANISOU 4 O PHE A 236 2495 3709 2873 652 -463 -341 O ATOM 5 CB PHE A 236 27.788 -57.075 -3.212 1.00 18.33 C ANISOU 5 CB PHE A 236 2128 2740 2095 -250 490 -251 C ATOM 6 CG PHE A 236 26.372 -57.529 -3.244 1.00 17.91 C ANISOU 6 CG PHE A 236 2265 2669 1871 -198 601 -605 C ATOM 7 CD1 PHE A 236 25.446 -56.810 -3.938 1.00 18.63 C ANISOU 7 CD1 PHE A 236 2419 2747 1911 -249 408 -708 C ATOM 8 CD2 PHE A 236 26.009 -58.685 -2.606 1.00 17.74 C ANISOU 8 CD2 PHE A 236 2322 2534 1885 -335 130 -490 C ATOM 9 CE1 PHE A 236 24.136 -57.259 -3.999 1.00 19.39 C ANISOU 9 CE1 PHE A 236 2713 2958 1698 -271 53 -590 C ATOM 10 CE2 PHE A 236 24.674 -59.144 -2.663 1.00 18.13 C ANISOU 10 CE2 PHE A 236 2516 2374 1997 -586 224 -838 C ATOM 11 CZ PHE A 236 23.773 -58.428 -3.372 1.00 17.87 C ANISOU 11 CZ PHE A 236 2719 2642 1430 -217 56 -634 C ATOM 12 HA PHE A 236 27.463 -55.203 -2.396 1.00 24.11 H ATOM 13 HB2 PHE A 236 28.016 -56.754 -4.098 1.00 22.01 H ATOM 14 HB3 PHE A 236 28.339 -57.841 -2.988 1.00 22.01 H ATOM 15 HD1 PHE A 236 25.695 -56.032 -4.383 1.00 22.36 H ATOM 16 HD2 PHE A 236 26.648 -59.178 -2.143 1.00 21.31 H ATOM 17 HE1 PHE A 236 23.500 -56.771 -4.471 1.00 23.29 H ATOM 18 HE2 PHE A 236 24.423 -59.929 -2.232 1.00 21.77 H ATOM 19 HZ PHE A 236 22.886 -58.706 -3.399 1.00 21.46 H ATOM 20 N LYS A 237 26.611 -56.030 -0.274 1.00 17.76 N ANISOU 20 N LYS A 237 1921 2702 2124 -483 -27 -828 N ATOM 21 CA LYS A 237 26.129 -56.425 1.065 1.00 16.84 C ANISOU 21 CA LYS A 237 2110 2357 1934 -166 -118 -814 C ATOM 22 C LYS A 237 24.751 -57.110 0.962 1.00 16.50 C ANISOU 22 C LYS A 237 2081 2396 1794 -143 288 -585 C ATOM 23 O LYS A 237 23.907 -56.785 0.125 1.00 16.10 O ANISOU 23 O LYS A 237 1892 2255 1970 -163 -152 -633 O ATOM 24 CB LYS A 237 25.953 -55.195 1.914 1.00 19.47 C ANISOU 24 CB LYS A 237 2684 2416 2299 -155 20 -699 C ATOM 25 CG LYS A 237 27.240 -54.508 2.233 1.00 26.65 C ANISOU 25 CG LYS A 237 3598 3119 3407 -368 -306 -1503 C ATOM 26 CD LYS A 237 26.942 -53.392 3.245 1.00 32.39 C ANISOU 26 CD LYS A 237 4024 3950 4334 -415 -231 -811 C ATOM 27 CE LYS A 237 28.210 -52.581 3.550 1.00 38.42 C ANISOU 27 CE LYS A 237 4747 4856 4994 -347 22 -648 C ATOM 28 NZ LYS A 237 28.051 -51.508 4.599 1.00 43.33 N ANISOU 28 NZ LYS A 237 5322 5482 5659 172 292 -530 N ATOM 29 H LYS A 237 26.074 -55.499 -0.686 1.00 21.32 H ATOM 30 HA LYS A 237 26.766 -57.032 1.496 1.00 20.23 H ATOM 31 HB2 LYS A 237 25.389 -54.564 1.439 1.00 23.38 H ATOM 32 HB3 LYS A 237 25.534 -55.448 2.751 1.00 23.38 H ATOM 33 HG2 LYS A 237 27.861 -55.137 2.632 1.00 31.99 H ATOM 34 HG3 LYS A 237 27.613 -54.113 1.430 1.00 31.99 H ATOM 35 HD2 LYS A 237 26.276 -52.791 2.875 1.00 38.89 H ATOM 36 HD3 LYS A 237 26.622 -53.784 4.072 1.00 38.89 H ATOM 37 HE2 LYS A 237 28.898 -53.191 3.859 1.00 46.11 H ATOM 38 HE3 LYS A 237 28.503 -52.149 2.733 1.00 46.11 H ATOM 39 HZ1 LYS A 237 28.885 -51.051 4.730 1.00 52.01 H ATOM 40 HZ2 LYS A 237 27.388 -50.872 4.321 1.00 52.01 H ATOM 41 HZ3 LYS A 237 27.777 -51.900 5.432 1.00 52.01 H ATOM 42 N GLY A 238 24.546 -58.104 1.840 1.00 16.43 N ANISOU 42 N GLY A 238 2179 2093 1970 -52 394 -276 N ATOM 43 CA GLY A 238 23.288 -58.808 1.994 1.00 17.39 C ANISOU 43 CA GLY A 238 2378 2296 1934 108 308 -66 C ATOM 44 C GLY A 238 22.253 -57.952 2.655 1.00 15.25 C ANISOU 44 C GLY A 238 1950 2356 1488 124 -13 -219 C ATOM 45 O GLY A 238 22.536 -56.873 3.202 1.00 15.79 O ANISOU 45 O GLY A 238 2061 2252 1686 -69 206 -443 O ATOM 46 H GLY A 238 25.155 -58.390 2.376 1.00 19.73 H ATOM 47 HA2 GLY A 238 22.956 -59.077 1.122 1.00 20.88 H ATOM 48 HA3 GLY A 238 23.423 -59.603 2.533 1.00 20.88 H ATOM 49 N LEU A 239 21.002 -58.390 2.557 1.00 14.22 N ANISOU 49 N LEU A 239 1737 2314 1352 -97 -104 -133 N ATOM 50 CA LEU A 239 19.916 -57.591 2.990 1.00 15.50 C ANISOU 50 CA LEU A 239 1785 2416 1688 -88 -186 -66 C ATOM 51 C LEU A 239 19.968 -57.222 4.485 1.00 13.99 C ANISOU 51 C LEU A 239 1652 2177 1485 -42 -174 -348 C ATOM 52 O LEU A 239 19.654 -56.085 4.831 1.00 14.73 O ANISOU 52 O LEU A 239 1817 2188 1592 210 -35 -241 O ATOM 53 CB LEU A 239 18.600 -58.288 2.691 1.00 16.20 C ANISOU 53 CB LEU A 239 2204 2312 1641 -34 -205 -62 C ATOM 54 CG LEU A 239 18.277 -58.447 1.211 1.00 17.97 C ANISOU 54 CG LEU A 239 2467 2453 1907 220 -186 -342 C ATOM 55 CD1 LEU A 239 17.086 -59.456 1.048 1.00 21.82 C ANISOU 55 CD1 LEU A 239 2855 2588 2849 413 -1095 -259 C ATOM 56 CD2 LEU A 239 17.926 -57.134 0.567 1.00 18.24 C ANISOU 56 CD2 LEU A 239 2653 2570 1709 449 -153 -344 C ATOM 57 H LEU A 239 20.775 -59.155 2.237 1.00 17.08 H ATOM 58 HA LEU A 239 19.927 -56.754 2.481 1.00 18.61 H ATOM 59 HB2 LEU A 239 18.625 -59.176 3.082 1.00 19.46 H ATOM 60 HB3 LEU A 239 17.881 -57.776 3.094 1.00 19.46 H ATOM 61 HG LEU A 239 19.050 -58.813 0.753 1.00 21.57 H ATOM 62 HD11 LEU A 239 16.886 -59.553 0.114 1.00 26.20 H ATOM 63 HD12 LEU A 239 17.342 -60.303 1.418 1.00 26.20 H ATOM 64 HD13 LEU A 239 16.320 -59.112 1.513 1.00 26.20 H ATOM 65 HD21 LEU A 239 17.732 -57.284 -0.361 1.00 21.91 H ATOM 66 HD22 LEU A 239 17.156 -56.766 1.007 1.00 21.91 H ATOM 67 HD23 LEU A 239 18.671 -56.534 0.653 1.00 21.91 H ATOM 68 N ASP A 240 20.282 -58.182 5.345 1.00 14.67 N ANISOU 68 N ASP A 240 2200 2010 1365 -166 91 -210 N ATOM 69 CA ASP A 240 20.253 -57.923 6.782 1.00 14.96 C ANISOU 69 CA ASP A 240 2312 2160 1212 -101 353 -359 C ATOM 70 C ASP A 240 21.196 -56.760 7.103 1.00 14.31 C ANISOU 70 C ASP A 240 2150 1858 1429 149 189 -246 C ATOM 71 O ASP A 240 20.905 -55.900 7.954 1.00 15.70 O ANISOU 71 O ASP A 240 2420 1958 1588 -107 434 -299 O ATOM 72 CB ASP A 240 20.630 -59.180 7.558 1.00 18.79 C ANISOU 72 CB ASP A 240 3267 2309 1562 -389 466 -62 C ATOM 73 CG ASP A 240 20.618 -58.978 9.121 1.00 25.36 C ANISOU 73 CG ASP A 240 3640 3063 2932 -110 -160 56 C ATOM 74 OD1 ASP A 240 19.545 -59.126 9.691 1.00 29.21 O ANISOU 74 OD1 ASP A 240 4680 3046 3374 560 660 -148 O ATOM 75 OD2 ASP A 240 21.700 -58.763 9.676 1.00 31.67 O ANISOU 75 OD2 ASP A 240 5197 3646 3191 10 -290 -22 O ATOM 76 H ASP A 240 20.513 -58.982 5.128 1.00 17.62 H ATOM 77 HA ASP A 240 19.346 -57.662 7.045 1.00 17.96 H ATOM 78 HB2 ASP A 240 19.996 -59.882 7.344 1.00 22.56 H ATOM 79 HB3 ASP A 240 21.524 -59.452 7.299 1.00 22.56 H ATOM 80 N SER A 241 22.308 -56.675 6.423 1.00 12.58 N ANISOU 80 N SER A 241 1744 1543 1494 176 21 -271 N ATOM 81 CA SER A 241 23.325 -55.689 6.774 1.00 14.22 C ANISOU 81 CA SER A 241 1645 1905 1854 264 -69 -82 C ATOM 82 C SER A 241 22.919 -54.291 6.391 1.00 14.46 C ANISOU 82 C SER A 241 1830 1523 2141 195 297 -20 C ATOM 83 O SER A 241 23.494 -53.305 6.913 1.00 18.65 O ANISOU 83 O SER A 241 2347 1769 2970 -278 -44 -385 O ATOM 84 CB SER A 241 24.667 -56.024 6.167 1.00 18.24 C ANISOU 84 CB SER A 241 1726 2516 2688 514 168 -208 C ATOM 85 OG SER A 241 24.685 -55.784 4.809 1.00 20.82 O ANISOU 85 OG SER A 241 1846 3200 2865 401 412 -429 O ATOM 86 H SER A 241 22.511 -57.172 5.751 1.00 15.12 H ATOM 87 HA SER A 241 23.437 -55.701 7.747 1.00 17.08 H ATOM 88 HB2 SER A 241 25.347 -55.478 6.591 1.00 21.90 H ATOM 89 HB3 SER A 241 24.855 -56.963 6.322 1.00 21.90 H ATOM 90 HG SER A 241 23.956 -55.499 4.565 1.00 25.00 H ATOM 91 N LYS A 242 21.937 -54.160 5.488 1.00 12.73 N ANISOU 91 N LYS A 242 1589 1494 1753 495 278 -112 N ATOM 92 CA LYS A 242 21.552 -52.853 4.981 1.00 13.00 C ANISOU 92 CA LYS A 242 1800 1566 1573 499 613 144 C ATOM 93 C LYS A 242 20.295 -52.309 5.629 1.00 11.63 C ANISOU 93 C LYS A 242 1577 1333 1509 252 274 -45 C ATOM 94 O LYS A 242 19.848 -51.221 5.236 1.00 13.64 O ANISOU 94 O LYS A 242 1662 1617 1903 479 566 328 O ATOM 95 CB LYS A 242 21.382 -52.938 3.494 1.00 17.81 C ANISOU 95 CB LYS A 242 2440 2177 2151 685 944 318 C ATOM 96 CG LYS A 242 22.792 -53.046 2.843 1.00 19.37 C ANISOU 96 CG LYS A 242 2779 2508 2074 548 1004 347 C ATOM 97 CD LYS A 242 22.817 -52.814 1.424 1.00 18.76 C ANISOU 97 CD LYS A 242 2904 2452 1772 74 491 123 C ATOM 98 CE LYS A 242 21.979 -53.865 0.690 1.00 16.84 C ANISOU 98 CE LYS A 242 2632 2175 1589 -281 219 -348 C ATOM 99 NZ LYS A 242 22.262 -53.620 -0.818 1.00 19.50 N ANISOU 99 NZ LYS A 242 2724 2183 2504 -262 787 -878 N ATOM 100 H LYS A 242 21.486 -54.814 5.159 1.00 15.29 H ATOM 101 HA LYS A 242 22.278 -52.219 5.162 1.00 15.62 H ATOM 102 HB2 LYS A 242 20.869 -53.729 3.266 1.00 21.39 H ATOM 103 HB3 LYS A 242 20.945 -52.136 3.166 1.00 21.39 H ATOM 104 HG2 LYS A 242 23.376 -52.391 3.257 1.00 23.26 H ATOM 105 HG3 LYS A 242 23.139 -53.938 3.001 1.00 23.26 H ATOM 106 HD2 LYS A 242 22.446 -51.938 1.234 1.00 22.53 H ATOM 107 HD3 LYS A 242 23.730 -52.872 1.104 1.00 22.53 H ATOM 108 HE2 LYS A 242 22.266 -54.759 0.932 1.00 20.22 H ATOM 109 HE3 LYS A 242 21.035 -53.732 0.867 1.00 20.22 H ATOM 110 HZ1 LYS A 242 21.767 -54.247 -1.351 1.00 23.42 H ATOM 111 HZ2 LYS A 242 22.000 -52.729 -1.061 1.00 23.42 H ATOM 112 HZ3 LYS A 242 23.199 -53.729 -0.998 1.00 23.42 H ATOM 113 N THR A 243 19.831 -52.948 6.682 1.00 11.27 N ANISOU 113 N THR A 243 1555 1389 1340 324 354 -100 N ATOM 114 CA THR A 243 18.689 -52.469 7.427 1.00 10.93 C ANISOU 114 CA THR A 243 1467 1489 1197 67 253 11 C ATOM 115 C THR A 243 19.123 -52.164 8.839 1.00 10.35 C ANISOU 115 C THR A 243 1130 1439 1364 153 162 4 C ATOM 116 O THR A 243 19.962 -52.861 9.406 1.00 11.83 O ANISOU 116 O THR A 243 1283 1653 1557 255 -20 -147 O ATOM 117 CB THR A 243 17.545 -53.517 7.444 1.00 14.00 C ANISOU 117 CB THR A 243 2040 1808 1471 -340 21 -42 C ATOM 118 OG1 THR A 243 16.972 -53.640 6.186 1.00 21.18 O ANISOU 118 OG1 THR A 243 3301 2805 1943 -1057 -388 229 O ATOM 119 CG2 THR A 243 16.454 -53.137 8.370 1.00 17.12 C ANISOU 119 CG2 THR A 243 1636 2135 2731 -378 547 -75 C ATOM 120 H THR A 243 20.167 -53.676 6.992 1.00 13.54 H ATOM 121 HA THR A 243 18.351 -51.644 7.018 1.00 13.13 H ATOM 122 HB THR A 243 17.898 -54.377 7.722 1.00 16.82 H ATOM 123 HG1 THR A 243 17.537 -53.879 5.642 1.00 25.43 H ATOM 124 HG21 THR A 243 15.764 -53.806 8.356 1.00 20.55 H ATOM 125 HG22 THR A 243 16.795 -53.059 9.264 1.00 20.55 H ATOM 126 HG23 THR A 243 16.077 -52.295 8.105 1.00 20.55 H ATOM 127 N PHE A 244 18.483 -51.133 9.431 1.00 9.58 N ANISOU 127 N PHE A 244 1054 1447 1141 233 7 -220 N ATOM 128 CA PHE A 244 18.666 -50.923 10.854 1.00 9.96 C ANISOU 128 CA PHE A 244 1050 1310 1424 46 75 -160 C ATOM 129 C PHE A 244 17.362 -50.455 11.422 1.00 9.04 C ANISOU 129 C PHE A 244 985 1235 1217 -76 3 -231 C ATOM 130 O PHE A 244 16.614 -49.677 10.785 1.00 9.78 O ANISOU 130 O PHE A 244 875 1554 1289 89 1 -103 O ATOM 131 CB PHE A 244 19.830 -49.950 11.200 1.00 10.91 C ANISOU 131 CB PHE A 244 1078 1513 1553 -15 -21 -144 C ATOM 132 CG PHE A 244 19.658 -48.563 10.690 1.00 10.88 C ANISOU 132 CG PHE A 244 925 1483 1725 -87 -18 -103 C ATOM 133 CD1 PHE A 244 19.154 -47.561 11.509 1.00 12.55 C ANISOU 133 CD1 PHE A 244 1096 1530 2142 -94 -154 -351 C ATOM 134 CD2 PHE A 244 20.080 -48.201 9.384 1.00 12.29 C ANISOU 134 CD2 PHE A 244 1139 1719 1811 -81 41 29 C ATOM 135 CE1 PHE A 244 19.032 -46.282 11.054 1.00 13.63 C ANISOU 135 CE1 PHE A 244 1464 1554 2162 -173 -486 -212 C ATOM 136 CE2 PHE A 244 19.972 -46.887 8.905 1.00 14.05 C ANISOU 136 CE2 PHE A 244 1487 1690 2159 -520 -470 234 C ATOM 137 CZ PHE A 244 19.473 -45.921 9.782 1.00 14.77 C ANISOU 137 CZ PHE A 244 1468 1563 2579 -405 -699 51 C ATOM 138 H PHE A 244 17.964 -50.571 9.039 1.00 11.52 H ATOM 139 HA PHE A 244 18.874 -51.786 11.270 1.00 11.97 H ATOM 140 HB2 PHE A 244 19.914 -49.899 12.165 1.00 13.11 H ATOM 141 HB3 PHE A 244 20.650 -50.302 10.820 1.00 13.11 H ATOM 142 HD1 PHE A 244 18.883 -47.768 12.374 1.00 15.07 H ATOM 143 HD2 PHE A 244 20.442 -48.855 8.830 1.00 14.76 H ATOM 144 HE1 PHE A 244 18.690 -45.628 11.620 1.00 16.37 H ATOM 145 HE2 PHE A 244 20.248 -46.662 8.046 1.00 16.87 H ATOM 146 HZ PHE A 244 19.356 -45.047 9.485 1.00 17.73 H ATOM 147 N LEU A 245 17.040 -50.928 12.621 1.00 9.01 N ANISOU 147 N LEU A 245 978 1192 1253 -124 33 -128 N ATOM 148 CA LEU A 245 15.832 -50.540 13.345 1.00 9.47 C ANISOU 148 CA LEU A 245 979 1267 1351 -182 121 -220 C ATOM 149 C LEU A 245 16.146 -49.359 14.243 1.00 8.72 C ANISOU 149 C LEU A 245 844 1394 1074 -124 -144 -222 C ATOM 150 O LEU A 245 17.179 -49.304 14.862 1.00 10.83 O ANISOU 150 O LEU A 245 1043 1475 1595 135 -380 -414 O ATOM 151 CB LEU A 245 15.395 -51.698 14.215 1.00 11.58 C ANISOU 151 CB LEU A 245 1308 1524 1567 -349 134 -480 C ATOM 152 CG LEU A 245 15.116 -53.036 13.555 1.00 13.67 C ANISOU 152 CG LEU A 245 2025 1549 1618 -477 379 49 C ATOM 153 CD1 LEU A 245 14.753 -54.119 14.588 1.00 22.27 C ANISOU 153 CD1 LEU A 245 3231 2463 2768 -1156 240 -18 C ATOM 154 CD2 LEU A 245 14.074 -52.902 12.496 1.00 16.90 C ANISOU 154 CD2 LEU A 245 2290 2082 2048 -628 -237 -197 C ATOM 155 H LEU A 245 17.523 -51.495 13.051 1.00 10.83 H ATOM 156 HA LEU A 245 15.114 -50.303 12.722 1.00 11.38 H ATOM 157 HB2 LEU A 245 16.088 -51.850 14.875 1.00 13.91 H ATOM 158 HB3 LEU A 245 14.579 -51.434 14.669 1.00 13.91 H ATOM 159 HG LEU A 245 15.930 -53.327 13.115 1.00 16.41 H ATOM 160 HD11 LEU A 245 14.585 -54.945 14.128 1.00 26.74 H ATOM 161 HD12 LEU A 245 15.486 -54.227 15.199 1.00 26.74 H ATOM 162 HD13 LEU A 245 13.966 -53.844 15.065 1.00 26.74 H ATOM 163 HD21 LEU A 245 13.920 -53.762 12.099 1.00 20.29 H ATOM 164 HD22 LEU A 245 13.264 -52.576 12.895 1.00 20.29 H ATOM 165 HD23 LEU A 245 14.383 -52.284 11.830 1.00 20.29 H ATOM 166 N SER A 246 15.190 -48.423 14.333 1.00 9.64 N ANISOU 166 N SER A 246 903 1497 1265 74 -147 -390 N ATOM 167 CA SER A 246 15.313 -47.352 15.313 1.00 9.59 C ANISOU 167 CA SER A 246 1016 1445 1183 -114 -240 -340 C ATOM 168 C SER A 246 13.956 -47.124 15.952 1.00 9.99 C ANISOU 168 C SER A 246 937 1317 1540 -160 -337 -226 C ATOM 169 O SER A 246 12.894 -47.419 15.387 1.00 12.07 O ANISOU 169 O SER A 246 1173 2113 1302 -47 -283 -763 O ATOM 170 CB SER A 246 15.889 -46.115 14.704 1.00 10.69 C ANISOU 170 CB SER A 246 1258 1499 1306 -92 -174 -410 C ATOM 171 OG SER A 246 15.107 -45.631 13.659 1.00 11.24 O ANISOU 171 OG SER A 246 1420 1548 1303 35 -228 -383 O ATOM 172 H SER A 246 14.480 -48.392 13.849 1.00 11.59 H ATOM 173 HA SER A 246 15.926 -47.644 16.020 1.00 11.52 H ATOM 174 HB2 SER A 246 15.952 -45.431 15.389 1.00 12.85 H ATOM 175 HB3 SER A 246 16.774 -46.319 14.363 1.00 12.85 H ATOM 176 HG SER A 246 15.447 -44.954 13.345 1.00 13.51 H ATOM 177 N GLU A 247 13.986 -46.574 17.157 1.00 8.96 N ANISOU 177 N GLU A 247 1182 1193 1029 -102 -265 -311 N ATOM 178 CA GLU A 247 12.790 -46.156 17.867 1.00 8.52 C ANISOU 178 CA GLU A 247 1179 945 1113 -122 -133 -78 C ATOM 179 C GLU A 247 12.946 -44.689 18.171 1.00 7.73 C ANISOU 179 C GLU A 247 958 1094 884 -96 -138 -144 C ATOM 180 O GLU A 247 14.048 -44.242 18.483 1.00 9.11 O ANISOU 180 O GLU A 247 1205 1067 1191 -92 -377 -110 O ATOM 181 CB GLU A 247 12.624 -46.920 19.175 1.00 9.91 C ANISOU 181 CB GLU A 247 1435 1005 1327 -22 -104 -163 C ATOM 182 CG GLU A 247 11.342 -46.691 19.899 1.00 11.66 C ANISOU 182 CG GLU A 247 1888 1189 1352 -77 -3 154 C ATOM 183 CD GLU A 247 11.500 -47.328 21.274 1.00 14.88 C ANISOU 183 CD GLU A 247 2774 1031 1848 80 193 -18 C ATOM 184 OE1 GLU A 247 11.142 -48.513 21.444 1.00 16.21 O ANISOU 184 OE1 GLU A 247 3207 1300 1651 36 248 199 O ATOM 185 OE2 GLU A 247 12.002 -46.640 22.196 1.00 19.45 O ANISOU 185 OE2 GLU A 247 4533 1128 1729 134 -59 74 O ATOM 186 H GLU A 247 14.711 -46.429 17.597 1.00 10.76 H ATOM 187 HA GLU A 247 11.996 -46.290 17.308 1.00 10.24 H ATOM 188 HB2 GLU A 247 12.684 -47.870 18.985 1.00 11.91 H ATOM 189 HB3 GLU A 247 13.344 -46.664 19.772 1.00 11.91 H ATOM 190 HG2 GLU A 247 11.181 -45.740 20.004 1.00 14.00 H ATOM 191 HG3 GLU A 247 10.610 -47.122 19.430 1.00 14.00 H ATOM 192 N HIS A 248 11.835 -43.983 18.115 1.00 8.48 N ANISOU 192 N HIS A 248 1061 952 1209 -203 -16 -38 N ATOM 193 CA HIS A 248 11.802 -42.557 18.339 1.00 8.72 C ANISOU 193 CA HIS A 248 1066 970 1276 -191 30 -39 C ATOM 194 C HIS A 248 10.668 -42.162 19.239 1.00 8.88 C ANISOU 194 C HIS A 248 1256 1130 988 -242 40 -178 C ATOM 195 O HIS A 248 9.632 -42.805 19.249 1.00 10.05 O ANISOU 195 O HIS A 248 1322 1245 1250 -304 264 -96 O ATOM 196 CB HIS A 248 11.680 -41.801 16.987 1.00 9.05 C ANISOU 196 CB HIS A 248 1036 1054 1349 -107 -153 104 C ATOM 197 CG HIS A 248 12.716 -42.168 16.005 1.00 9.01 C ANISOU 197 CG HIS A 248 1159 1047 1218 -45 22 -201 C ATOM 198 ND1 HIS A 248 13.822 -41.404 15.738 1.00 9.15 N ANISOU 198 ND1 HIS A 248 1164 1155 1158 -280 -91 -135 N ATOM 199 CD2 HIS A 248 12.857 -43.276 15.251 1.00 9.16 C ANISOU 199 CD2 HIS A 248 986 1258 1237 -163 29 -83 C ATOM 200 CE1 HIS A 248 14.598 -42.044 14.851 1.00 9.58 C ANISOU 200 CE1 HIS A 248 1337 1101 1202 -284 73 -185 C ATOM 201 NE2 HIS A 248 14.039 -43.199 14.552 1.00 9.83 N ANISOU 201 NE2 HIS A 248 1184 1238 1313 47 -41 -88 N ATOM 202 H HIS A 248 11.063 -44.320 17.942 1.00 10.19 H ATOM 203 HA HIS A 248 12.639 -42.281 18.767 1.00 10.47 H ATOM 204 HB2 HIS A 248 10.815 -42.001 16.595 1.00 10.88 H ATOM 205 HB3 HIS A 248 11.753 -40.849 17.154 1.00 10.88 H ATOM 206 HD2 HIS A 248 12.268 -43.996 15.236 1.00 11.01 H ATOM 207 HE1 HIS A 248 15.396 -41.722 14.499 1.00 11.51 H ATOM 208 N SER A 249 10.820 -41.055 19.958 1.00 10.54 N ANISOU 208 N SER A 249 1432 1240 1332 -204 140 -363 N ATOM 209 CA SER A 249 9.672 -40.402 20.573 1.00 11.37 C ANISOU 209 CA SER A 249 1830 1337 1152 -99 270 -330 C ATOM 210 C SER A 249 8.867 -39.717 19.443 1.00 11.01 C ANISOU 210 C SER A 249 1618 1319 1248 34 278 -248 C ATOM 211 O SER A 249 9.250 -39.702 18.254 1.00 10.66 O ANISOU 211 O SER A 249 1438 1242 1372 -6 124 -225 O ATOM 212 CB SER A 249 10.132 -39.469 21.669 1.00 14.32 C ANISOU 212 CB SER A 249 2170 1575 1697 -222 486 -482 C ATOM 213 OG SER A 249 11.246 -38.738 21.374 1.00 17.19 O ANISOU 213 OG SER A 249 2885 1642 2005 -405 785 -615 O ATOM 214 H SER A 249 11.572 -40.664 20.104 1.00 12.66 H ATOM 215 HA SER A 249 9.099 -41.084 20.980 1.00 13.65 H ATOM 216 HB2 SER A 249 9.409 -38.852 21.864 1.00 17.20 H ATOM 217 HB3 SER A 249 10.320 -40.000 22.459 1.00 17.20 H ATOM 218 HG SER A 249 11.509 -38.920 20.619 1.00 20.64 H ATOM 219 N MET A 250 7.717 -39.166 19.802 1.00 13.54 N ANISOU 219 N MET A 250 1860 1699 1585 152 530 -365 N ATOM 220 CA MET A 250 6.801 -38.663 18.798 1.00 14.36 C ANISOU 220 CA MET A 250 1750 2031 1675 308 205 -359 C ATOM 221 C MET A 250 7.311 -37.465 18.035 1.00 15.73 C ANISOU 221 C MET A 250 1914 1830 2232 346 334 -143 C ATOM 222 O MET A 250 6.789 -37.166 16.947 1.00 16.82 O ANISOU 222 O MET A 250 2116 2072 2204 368 103 -236 O ATOM 223 CB MET A 250 5.443 -38.375 19.382 1.00 16.09 C ANISOU 223 CB MET A 250 1945 2016 2151 65 615 -551 C ATOM 224 CG MET A 250 4.757 -39.627 19.952 1.00 17.91 C ANISOU 224 CG MET A 250 1881 2230 2694 123 686 -501 C ATOM 225 SD MET A 250 4.596 -41.036 18.819 1.00 17.91 S ANISOU 225 SD MET A 250 2132 1983 2688 46 826 -446 S ATOM 226 CE MET A 250 3.726 -40.335 17.485 1.00 17.76 C ANISOU 226 CE MET A 250 1885 2007 2856 60 497 -87 C ATOM 227 H MET A 250 7.446 -39.074 20.613 1.00 16.26 H ATOM 228 HA MET A 250 6.669 -39.382 18.146 1.00 17.25 H ATOM 229 HB2 MET A 250 5.540 -37.733 20.103 1.00 19.32 H ATOM 230 HB3 MET A 250 4.872 -38.011 18.688 1.00 19.32 H ATOM 231 HG2 MET A 250 5.267 -39.931 20.720 1.00 21.51 H ATOM 232 HG3 MET A 250 3.863 -39.382 20.237 1.00 21.51 H ATOM 233 HE1 MET A 250 3.585 -41.009 16.816 1.00 21.33 H ATOM 234 HE2 MET A 250 2.881 -40.006 17.802 1.00 21.33 H ATOM 235 HE3 MET A 250 4.243 -39.614 17.120 1.00 21.33 H ATOM 236 N ASP A 251 8.344 -36.803 18.598 1.00 14.94 N ANISOU 236 N ASP A 251 2130 1641 1904 309 470 -46 N ATOM 237 CA ASP A 251 9.066 -35.706 17.942 1.00 15.38 C ANISOU 237 CA ASP A 251 2324 1479 2039 284 502 -244 C ATOM 238 C ASP A 251 10.265 -36.154 17.113 1.00 14.07 C ANISOU 238 C ASP A 251 2384 1174 1786 334 384 22 C ATOM 239 O ASP A 251 11.066 -35.319 16.666 1.00 16.24 O ANISOU 239 O ASP A 251 3028 1056 2086 196 557 20 O ATOM 240 CB ASP A 251 9.551 -34.717 19.041 1.00 18.21 C ANISOU 240 CB ASP A 251 2889 1893 2137 -56 668 -723 C ATOM 241 CG ASP A 251 10.415 -35.422 20.133 1.00 18.04 C ANISOU 241 CG ASP A 251 3185 1628 2041 -316 300 -655 C ATOM 242 OD1 ASP A 251 10.818 -36.574 19.937 1.00 17.09 O ANISOU 242 OD1 ASP A 251 2862 1685 1947 -56 439 -270 O ATOM 243 OD2 ASP A 251 10.644 -34.842 21.227 1.00 23.38 O ANISOU 243 OD2 ASP A 251 3627 2298 2957 -404 292 -1119 O ATOM 244 H ASP A 251 8.647 -36.982 19.383 1.00 17.94 H ATOM 245 HA ASP A 251 8.449 -35.226 17.351 1.00 18.47 H ATOM 246 HB2 ASP A 251 10.092 -34.025 18.629 1.00 21.87 H ATOM 247 HB3 ASP A 251 8.779 -34.322 19.476 1.00 21.87 H ATOM 248 N MET A 252 10.407 -37.456 16.909 1.00 11.32 N ANISOU 248 N MET A 252 1775 1149 1378 147 165 -24 N ATOM 249 CA MET A 252 11.469 -38.055 16.119 1.00 9.52 C ANISOU 249 CA MET A 252 1387 1028 1201 70 35 -47 C ATOM 250 C MET A 252 12.841 -38.071 16.804 1.00 10.37 C ANISOU 250 C MET A 252 1650 1026 1264 -144 25 46 C ATOM 251 O MET A 252 13.832 -38.506 16.184 1.00 10.29 O ANISOU 251 O MET A 252 1447 1114 1349 -213 17 -150 O ATOM 252 CB MET A 252 11.604 -37.564 14.699 1.00 11.17 C ANISOU 252 CB MET A 252 1430 1271 1543 -145 -269 54 C ATOM 253 CG MET A 252 10.454 -38.035 13.822 1.00 13.11 C ANISOU 253 CG MET A 252 1771 1670 1541 438 146 83 C ATOM 254 SD MET A 252 10.246 -39.851 13.692 1.00 13.24 S ANISOU 254 SD MET A 252 1385 1941 1706 -415 67 -76 S ATOM 255 CE MET A 252 11.742 -40.287 12.829 1.00 12.42 C ANISOU 255 CE MET A 252 1383 1495 1841 -287 94 40 C ATOM 256 H MET A 252 9.870 -38.041 17.237 1.00 13.60 H ATOM 257 HA MET A 252 11.215 -38.997 16.025 1.00 11.44 H ATOM 258 HB2 MET A 252 11.608 -36.594 14.697 1.00 13.42 H ATOM 259 HB3 MET A 252 12.431 -37.903 14.323 1.00 13.42 H ATOM 260 HG2 MET A 252 9.628 -37.673 14.179 1.00 15.75 H ATOM 261 HG3 MET A 252 10.595 -37.695 12.924 1.00 15.75 H ATOM 262 HE1 MET A 252 11.759 -41.237 12.693 1.00 14.92 H ATOM 263 HE2 MET A 252 11.757 -39.835 11.982 1.00 14.92 H ATOM 264 HE3 MET A 252 12.497 -40.018 13.357 1.00 14.92 H ATOM 265 N LYS A 253 12.907 -37.778 18.105 1.00 10.92 N ANISOU 265 N LYS A 253 1687 1155 1306 -139 31 -76 N ATOM 266 CA LYS A 253 14.171 -37.969 18.804 1.00 10.54 C ANISOU 266 CA LYS A 253 1845 1062 1097 -221 -38 -97 C ATOM 267 C LYS A 253 14.428 -39.493 18.922 1.00 10.18 C ANISOU 267 C LYS A 253 1186 1443 1239 -357 -175 -40 C ATOM 268 O LYS A 253 13.554 -40.257 19.328 1.00 10.81 O ANISOU 268 O LYS A 253 1426 1098 1585 -277 -44 -68 O ATOM 269 CB LYS A 253 14.131 -37.376 20.185 1.00 13.06 C ANISOU 269 CB LYS A 253 2150 1250 1564 -257 120 -220 C ATOM 270 CG LYS A 253 14.208 -35.852 20.203 1.00 16.00 C ANISOU 270 CG LYS A 253 2525 1715 1841 -395 -165 -618 C ATOM 271 CD LYS A 253 13.893 -35.294 21.563 1.00 22.22 C ANISOU 271 CD LYS A 253 3265 2334 2843 -370 -100 -1216 C ATOM 272 CE LYS A 253 14.937 -35.536 22.452 1.00 29.31 C ANISOU 272 CE LYS A 253 3702 3611 3823 -264 -8 -886 C ATOM 273 NZ LYS A 253 14.708 -34.549 23.679 1.00 33.28 N ANISOU 273 NZ LYS A 253 4397 4164 4084 -254 92 -979 N ATOM 274 H LYS A 253 12.260 -37.480 18.586 1.00 13.12 H ATOM 275 HA LYS A 253 14.902 -37.557 18.298 1.00 12.66 H ATOM 276 HB2 LYS A 253 13.300 -37.636 20.613 1.00 15.69 H ATOM 277 HB3 LYS A 253 14.883 -37.717 20.693 1.00 15.69 H ATOM 278 HG2 LYS A 253 15.106 -35.576 19.962 1.00 19.22 H ATOM 279 HG3 LYS A 253 13.566 -35.492 19.571 1.00 19.22 H ATOM 280 HD2 LYS A 253 13.764 -34.335 21.496 1.00 26.68 H ATOM 281 HD3 LYS A 253 13.092 -35.719 21.909 1.00 26.68 H ATOM 282 HE2 LYS A 253 14.906 -36.453 22.768 1.00 35.19 H ATOM 283 HE3 LYS A 253 15.789 -35.335 22.034 1.00 35.19 H ATOM 284 HZ1 LYS A 253 15.402 -34.670 24.331 1.00 39.95 H ATOM 285 HZ2 LYS A 253 14.721 -33.639 23.374 1.00 39.95 H ATOM 286 HZ3 LYS A 253 13.859 -34.728 24.090 1.00 39.95 H ATOM 287 N PHE A 254 15.662 -39.906 18.677 1.00 10.74 N ANISOU 287 N PHE A 254 1372 1274 1434 -545 -365 -18 N ATOM 288 CA PHE A 254 16.045 -41.308 18.845 1.00 10.00 C ANISOU 288 CA PHE A 254 1512 1145 1141 -231 -366 -73 C ATOM 289 C PHE A 254 15.918 -41.704 20.314 1.00 10.86 C ANISOU 289 C PHE A 254 1475 1146 1507 -220 -737 -251 C ATOM 290 O PHE A 254 16.461 -41.032 21.196 1.00 12.70 O ANISOU 290 O PHE A 254 1975 1313 1536 -263 -596 -168 O ATOM 291 CB PHE A 254 17.485 -41.552 18.415 1.00 11.13 C ANISOU 291 CB PHE A 254 1536 1314 1380 -100 -323 -24 C ATOM 292 CG PHE A 254 17.711 -41.637 16.934 1.00 10.91 C ANISOU 292 CG PHE A 254 1292 1285 1567 -76 -205 -221 C ATOM 293 CD1 PHE A 254 17.676 -42.878 16.276 1.00 11.70 C ANISOU 293 CD1 PHE A 254 1202 1407 1837 -115 -272 -223 C ATOM 294 CD2 PHE A 254 18.069 -40.527 16.210 1.00 11.19 C ANISOU 294 CD2 PHE A 254 1408 1399 1444 -283 -385 -29 C ATOM 295 CE1 PHE A 254 17.977 -42.977 14.935 1.00 12.62 C ANISOU 295 CE1 PHE A 254 1266 1607 1920 -86 -144 -411 C ATOM 296 CE2 PHE A 254 18.289 -40.604 14.857 1.00 12.19 C ANISOU 296 CE2 PHE A 254 1379 1476 1777 -234 -207 7 C ATOM 297 CZ PHE A 254 18.249 -41.840 14.224 1.00 12.53 C ANISOU 297 CZ PHE A 254 1446 1542 1775 -339 57 -23 C ATOM 298 H PHE A 254 16.301 -39.396 18.410 1.00 12.90 H ATOM 299 HA PHE A 254 15.455 -41.880 18.312 1.00 12.01 H ATOM 300 HB2 PHE A 254 18.033 -40.825 18.752 1.00 13.37 H ATOM 301 HB3 PHE A 254 17.783 -42.389 18.803 1.00 13.37 H ATOM 302 HD1 PHE A 254 17.491 -43.649 16.762 1.00 14.05 H ATOM 303 HD2 PHE A 254 18.084 -39.696 16.627 1.00 13.44 H ATOM 304 HE1 PHE A 254 17.916 -43.797 14.501 1.00 15.15 H ATOM 305 HE2 PHE A 254 18.508 -39.839 14.375 1.00 14.64 H ATOM 306 HZ PHE A 254 18.422 -41.897 13.312 1.00 15.06 H ATOM 307 N THR A 255 15.275 -42.830 20.572 1.00 10.62 N ANISOU 307 N THR A 255 1738 1178 1121 -199 -407 -240 N ATOM 308 CA THR A 255 15.217 -43.502 21.870 1.00 11.55 C ANISOU 308 CA THR A 255 2098 1276 1014 -178 -448 -168 C ATOM 309 C THR A 255 15.935 -44.842 21.825 1.00 11.65 C ANISOU 309 C THR A 255 2042 1306 1079 -222 -421 -28 C ATOM 310 O THR A 255 16.311 -45.350 22.886 1.00 13.19 O ANISOU 310 O THR A 255 2129 1605 1278 -197 -385 114 O ATOM 311 CB THR A 255 13.797 -43.610 22.376 1.00 14.01 C ANISOU 311 CB THR A 255 2421 1685 1220 -67 120 5 C ATOM 312 OG1 THR A 255 13.041 -44.317 21.417 1.00 14.64 O ANISOU 312 OG1 THR A 255 2244 1898 1418 -333 -116 -176 O ATOM 313 CG2 THR A 255 13.175 -42.287 22.710 1.00 16.58 C ANISOU 313 CG2 THR A 255 2330 1987 1984 115 -133 -126 C ATOM 314 H THR A 255 14.834 -43.256 19.969 1.00 12.76 H ATOM 315 HA THR A 255 15.703 -42.946 22.515 1.00 13.87 H ATOM 316 HB THR A 255 13.809 -44.133 23.193 1.00 16.83 H ATOM 317 HG1 THR A 255 13.356 -45.066 21.308 1.00 17.58 H ATOM 318 HG21 THR A 255 12.277 -42.418 23.025 1.00 19.92 H ATOM 319 HG22 THR A 255 13.685 -41.849 23.395 1.00 19.92 H ATOM 320 HG23 THR A 255 13.154 -41.728 21.930 1.00 19.92 H ATOM 321 N TYR A 256 16.183 -45.407 20.642 1.00 10.76 N ANISOU 321 N TYR A 256 1629 1213 1248 -235 -321 20 N ATOM 322 CA TYR A 256 16.894 -46.656 20.481 1.00 10.59 C ANISOU 322 CA TYR A 256 1382 1350 1292 -202 -322 37 C ATOM 323 C TYR A 256 17.379 -46.690 19.051 1.00 9.98 C ANISOU 323 C TYR A 256 1112 1236 1443 -318 -384 25 C ATOM 324 O TYR A 256 16.676 -46.253 18.149 1.00 9.38 O ANISOU 324 O TYR A 256 1108 1253 1204 -263 -243 1 O ATOM 325 CB TYR A 256 15.969 -47.879 20.762 1.00 10.97 C ANISOU 325 CB TYR A 256 1321 1232 1613 -209 -92 118 C ATOM 326 CG TYR A 256 16.541 -49.152 20.318 1.00 12.09 C ANISOU 326 CG TYR A 256 1753 1312 1530 -396 157 106 C ATOM 327 CD1 TYR A 256 16.262 -49.625 19.065 1.00 14.55 C ANISOU 327 CD1 TYR A 256 2133 1605 1790 -711 210 -191 C ATOM 328 CD2 TYR A 256 17.417 -49.879 21.127 1.00 14.12 C ANISOU 328 CD2 TYR A 256 2071 1544 1748 9 306 362 C ATOM 329 CE1 TYR A 256 16.806 -50.757 18.592 1.00 18.49 C ANISOU 329 CE1 TYR A 256 2656 2000 2369 -972 710 -732 C ATOM 330 CE2 TYR A 256 17.982 -50.999 20.612 1.00 16.24 C ANISOU 330 CE2 TYR A 256 2382 1577 2211 194 106 505 C ATOM 331 CZ TYR A 256 17.709 -51.411 19.328 1.00 18.36 C ANISOU 331 CZ TYR A 256 2733 1381 2862 -124 1021 -86 C ATOM 332 OH TYR A 256 18.293 -52.593 18.836 1.00 25.47 O ANISOU 332 OH TYR A 256 3852 1797 4029 -5 2007 -244 O ATOM 333 H TYR A 256 15.935 -45.063 19.894 1.00 12.93 H ATOM 334 HA TYR A 256 17.666 -46.688 21.085 1.00 12.73 H ATOM 335 HB2 TYR A 256 15.811 -47.940 21.717 1.00 13.17 H ATOM 336 HB3 TYR A 256 15.128 -47.751 20.296 1.00 13.17 H ATOM 337 HD1 TYR A 256 15.686 -49.140 18.519 1.00 17.47 H ATOM 338 HD2 TYR A 256 17.657 -49.567 21.970 1.00 16.95 H ATOM 339 HE1 TYR A 256 16.623 -51.035 17.724 1.00 22.20 H ATOM 340 HE2 TYR A 256 18.586 -51.482 21.127 1.00 19.50 H ATOM 341 HH TYR A 256 18.130 -53.218 19.342 1.00 30.58 H ATOM 342 N CYS A 257 18.546 -47.299 18.830 1.00 10.81 N ANISOU 342 N CYS A 257 1205 1454 1447 -311 -414 117 N ATOM 343 CA CYS A 257 18.989 -47.605 17.487 1.00 11.25 C ANISOU 343 CA CYS A 257 1123 1431 1719 -146 -228 282 C ATOM 344 C CYS A 257 19.772 -48.910 17.524 1.00 10.89 C ANISOU 344 C CYS A 257 1144 1571 1423 -338 -380 150 C ATOM 345 O CYS A 257 20.635 -49.044 18.377 1.00 12.14 O ANISOU 345 O CYS A 257 1338 1415 1859 -69 -593 -40 O ATOM 346 CB CYS A 257 19.791 -46.480 16.879 1.00 13.29 C ANISOU 346 CB CYS A 257 1480 1708 1861 -22 48 408 C ATOM 347 SG CYS A 257 20.059 -46.631 15.101 1.00 14.90 S ANISOU 347 SG CYS A 257 1607 2009 2044 38 119 515 S ATOM 348 H CYS A 257 19.094 -47.542 19.446 1.00 12.98 H ATOM 349 HA CYS A 257 18.201 -47.747 16.922 1.00 13.51 H ATOM 350 HB2 CYS A 257 19.323 -45.645 17.036 1.00 15.96 H ATOM 351 HB3 CYS A 257 20.661 -46.452 17.307 1.00 15.96 H ATOM 352 HG CYS A 257 20.777 -45.582 14.677 1.00 17.89 H ATOM 353 N ASP A 258 19.574 -49.793 16.558 1.00 11.63 N ANISOU 353 N ASP A 258 1288 1708 1423 -230 -254 44 N ATOM 354 CA ASP A 258 20.411 -50.979 16.493 1.00 12.58 C ANISOU 354 CA ASP A 258 1495 1660 1624 -317 -361 -204 C ATOM 355 C ASP A 258 21.785 -50.703 15.889 1.00 12.32 C ANISOU 355 C ASP A 258 1196 1721 1763 -185 -204 -13 C ATOM 356 O ASP A 258 22.020 -49.759 15.154 1.00 13.19 O ANISOU 356 O ASP A 258 1306 1752 1955 -83 -47 320 O ATOM 357 CB ASP A 258 19.737 -52.340 16.101 1.00 17.79 C ANISOU 357 CB ASP A 258 2382 2348 2031 -243 138 -348 C ATOM 358 CG ASP A 258 19.811 -52.667 14.607 1.00 14.07 C ANISOU 358 CG ASP A 258 1315 1965 2067 -597 57 -308 C ATOM 359 OD1 ASP A 258 20.946 -53.082 14.356 1.00 20.84 O ANISOU 359 OD1 ASP A 258 1694 2425 3800 -526 210 -907 O ATOM 360 OD2 ASP A 258 18.799 -52.849 13.858 1.00 13.75 O ANISOU 360 OD2 ASP A 258 1865 1470 1889 -285 -260 242 O ATOM 361 H ASP A 258 18.978 -49.732 15.941 1.00 13.97 H ATOM 362 HA ASP A 258 20.633 -51.137 17.434 1.00 15.11 H ATOM 363 HB2 ASP A 258 20.179 -53.056 16.583 1.00 21.37 H ATOM 364 HB3 ASP A 258 18.800 -52.306 16.350 1.00 21.37 H ATOM 365 N ASP A 259 22.721 -51.531 16.325 1.00 13.70 N ANISOU 365 N ASP A 259 1341 1806 2058 -39 -588 347 N ATOM 366 CA ASP A 259 24.125 -51.368 16.018 1.00 14.97 C ANISOU 366 CA ASP A 259 1538 1897 2254 83 -740 38 C ATOM 367 C ASP A 259 24.462 -51.532 14.538 1.00 13.40 C ANISOU 367 C ASP A 259 1384 1220 2489 74 -643 73 C ATOM 368 O ASP A 259 25.583 -51.178 14.136 1.00 14.72 O ANISOU 368 O ASP A 259 1179 1757 2659 -74 -390 226 O ATOM 369 CB ASP A 259 25.015 -52.309 16.902 1.00 19.76 C ANISOU 369 CB ASP A 259 1886 2823 2799 162 -1065 574 C ATOM 370 CG ASP A 259 24.916 -51.988 18.363 1.00 25.29 C ANISOU 370 CG ASP A 259 3051 2989 3571 -89 -1310 843 C ATOM 371 OD1 ASP A 259 25.514 -50.994 18.793 1.00 32.75 O ANISOU 371 OD1 ASP A 259 4410 3649 4382 568 -1557 880 O ATOM 372 OD2 ASP A 259 24.341 -52.808 19.097 1.00 35.92 O ANISOU 372 OD2 ASP A 259 4745 4360 4545 -276 -259 334 O ATOM 373 H ASP A 259 22.558 -52.216 16.818 1.00 16.45 H ATOM 374 HA ASP A 259 24.372 -50.450 16.257 1.00 17.98 H ATOM 375 HB2 ASP A 259 24.728 -53.227 16.776 1.00 23.73 H ATOM 376 HB3 ASP A 259 25.942 -52.211 16.635 1.00 23.73 H ATOM 377 N ARG A 260 23.550 -52.050 13.720 1.00 13.05 N ANISOU 377 N ARG A 260 1402 1393 2164 -20 -269 106 N ATOM 378 CA ARG A 260 23.798 -52.118 12.293 1.00 12.59 C ANISOU 378 CA ARG A 260 1153 1397 2234 14 -191 -48 C ATOM 379 C ARG A 260 24.043 -50.754 11.671 1.00 13.14 C ANISOU 379 C ARG A 260 1174 1458 2360 74 -139 -120 C ATOM 380 O ARG A 260 24.668 -50.672 10.622 1.00 15.02 O ANISOU 380 O ARG A 260 1558 1662 2486 130 248 -270 O ATOM 381 CB ARG A 260 22.650 -52.822 11.585 1.00 13.44 C ANISOU 381 CB ARG A 260 1368 1387 2351 -33 -373 -70 C ATOM 382 CG ARG A 260 22.719 -54.358 11.792 1.00 15.04 C ANISOU 382 CG ARG A 260 1815 1886 2014 -131 -274 -67 C ATOM 383 CD ARG A 260 21.584 -55.042 11.076 1.00 14.64 C ANISOU 383 CD ARG A 260 1827 1722 2012 37 48 -184 C ATOM 384 NE ARG A 260 20.311 -54.765 11.758 1.00 13.53 N ANISOU 384 NE ARG A 260 1851 1576 1716 22 -53 -172 N ATOM 385 CZ ARG A 260 19.124 -55.170 11.285 1.00 13.73 C ANISOU 385 CZ ARG A 260 2061 1651 1503 -111 187 -190 C ATOM 386 NH1 ARG A 260 19.077 -55.909 10.183 1.00 14.82 N ANISOU 386 NH1 ARG A 260 1914 1908 1808 -170 122 -49 N ATOM 387 NH2 ARG A 260 18.008 -54.876 11.923 1.00 18.04 N ANISOU 387 NH2 ARG A 260 2204 2473 2177 -144 391 -519 N ATOM 388 H ARG A 260 22.788 -52.364 13.966 1.00 15.68 H ATOM 389 HA ARG A 260 24.604 -52.654 12.147 1.00 15.13 H ATOM 390 HB2 ARG A 260 21.807 -52.504 11.944 1.00 16.14 H ATOM 391 HB3 ARG A 260 22.700 -52.640 10.633 1.00 16.14 H ATOM 392 HG2 ARG A 260 23.555 -54.695 11.433 1.00 18.06 H ATOM 393 HG3 ARG A 260 22.651 -54.560 12.738 1.00 18.06 H ATOM 394 HD2 ARG A 260 21.526 -54.707 10.167 1.00 17.58 H ATOM 395 HD3 ARG A 260 21.732 -56.001 11.076 1.00 17.58 H ATOM 396 HE ARG A 260 20.347 -54.432 12.669 1.00 16.26 H ATOM 397 HH11 ARG A 260 19.802 -56.099 9.762 1.00 17.80 H ATOM 398 HH12 ARG A 260 18.320 -56.180 9.879 1.00 17.80 H ATOM 399 HH21 ARG A 260 18.036 -54.409 12.645 1.00 21.66 H ATOM 400 HH22 ARG A 260 17.254 -55.158 11.622 1.00 21.66 H ATOM 401 N ILE A 261 23.595 -49.655 12.325 1.00 11.57 N ANISOU 401 N ILE A 261 1216 1347 1835 50 -109 33 N ATOM 402 CA ILE A 261 23.823 -48.340 11.790 1.00 11.68 C ANISOU 402 CA ILE A 261 1086 1384 1968 167 -259 138 C ATOM 403 C ILE A 261 25.304 -48.046 11.700 1.00 13.57 C ANISOU 403 C ILE A 261 915 1645 2594 100 -106 342 C ATOM 404 O ILE A 261 25.724 -47.273 10.842 1.00 15.15 O ANISOU 404 O ILE A 261 1332 1839 2584 50 150 360 O ATOM 405 CB ILE A 261 23.079 -47.278 12.604 1.00 12.19 C ANISOU 405 CB ILE A 261 1206 1375 2052 -84 -228 158 C ATOM 406 CG1 ILE A 261 22.923 -45.998 11.754 1.00 13.78 C ANISOU 406 CG1 ILE A 261 1447 1567 2222 47 -27 -138 C ATOM 407 CG2 ILE A 261 23.669 -47.022 13.958 1.00 13.12 C ANISOU 407 CG2 ILE A 261 1225 1613 2146 -140 -385 -94 C ATOM 408 CD1 ILE A 261 22.136 -44.905 12.393 1.00 14.37 C ANISOU 408 CD1 ILE A 261 1712 1656 2092 -163 -125 208 C ATOM 409 H ILE A 261 23.165 -49.668 13.070 1.00 13.90 H ATOM 410 HA ILE A 261 23.464 -48.313 10.879 1.00 14.03 H ATOM 411 HB ILE A 261 22.184 -47.621 12.755 1.00 14.65 H ATOM 412 HG12 ILE A 261 23.806 -45.647 11.561 1.00 16.55 H ATOM 413 HG13 ILE A 261 22.478 -46.231 10.925 1.00 16.55 H ATOM 414 HG21 ILE A 261 23.150 -46.348 14.402 1.00 15.75 H ATOM 415 HG22 ILE A 261 23.651 -47.837 14.465 1.00 15.75 H ATOM 416 HG23 ILE A 261 24.575 -46.721 13.852 1.00 15.75 H ATOM 417 HD11 ILE A 261 22.095 -44.157 11.791 1.00 17.26 H ATOM 418 HD12 ILE A 261 21.250 -45.225 12.578 1.00 17.26 H ATOM 419 HD13 ILE A 261 22.568 -44.645 13.210 1.00 17.26 H ATOM 420 N THR A 262 26.107 -48.596 12.594 1.00 15.17 N ANISOU 420 N THR A 262 836 1503 3425 40 -123 173 N ATOM 421 CA THR A 262 27.497 -48.147 12.678 1.00 15.20 C ANISOU 421 CA THR A 262 1002 1826 2946 244 -103 194 C ATOM 422 C THR A 262 28.253 -48.471 11.418 1.00 17.07 C ANISOU 422 C THR A 262 731 1891 3865 114 -55 186 C ATOM 423 O THR A 262 29.040 -47.648 10.933 1.00 19.62 O ANISOU 423 O THR A 262 1214 2043 4197 -296 601 -278 O ATOM 424 CB THR A 262 28.154 -48.787 13.952 1.00 16.24 C ANISOU 424 CB THR A 262 1090 1760 3322 -60 -344 26 C ATOM 425 OG1 THR A 262 27.323 -48.473 15.069 1.00 17.29 O ANISOU 425 OG1 THR A 262 1704 1754 3110 -91 -729 253 O ATOM 426 CG2 THR A 262 29.512 -48.241 14.202 1.00 19.59 C ANISOU 426 CG2 THR A 262 1549 2510 3386 -211 -584 222 C ATOM 427 H THR A 262 25.887 -49.213 13.151 1.00 18.22 H ATOM 428 HA THR A 262 27.509 -47.174 12.791 1.00 18.25 H ATOM 429 HB THR A 262 28.215 -49.749 13.846 1.00 19.51 H ATOM 430 HG1 THR A 262 27.269 -47.659 15.158 1.00 20.76 H ATOM 431 HG21 THR A 262 29.890 -48.648 14.985 1.00 23.53 H ATOM 432 HG22 THR A 262 30.081 -48.422 13.450 1.00 23.53 H ATOM 433 HG23 THR A 262 29.464 -47.291 14.335 1.00 23.53 H ATOM 434 N GLU A 263 28.127 -49.713 10.934 1.00 18.17 N ANISOU 434 N GLU A 263 1494 2004 3408 -10 68 -135 N ATOM 435 CA GLU A 263 28.848 -50.106 9.775 1.00 21.86 C ANISOU 435 CA GLU A 263 2036 2387 3885 -117 600 -189 C ATOM 436 C GLU A 263 28.345 -49.395 8.557 1.00 20.53 C ANISOU 436 C GLU A 263 1932 2486 3384 -3 1144 -404 C ATOM 437 O GLU A 263 29.069 -49.257 7.592 1.00 25.44 O ANISOU 437 O GLU A 263 2183 3363 4119 341 1233 -72 O ATOM 438 CB GLU A 263 28.786 -51.608 9.523 1.00 25.00 C ANISOU 438 CB GLU A 263 3140 2903 3455 333 498 -269 C ATOM 439 CG GLU A 263 29.713 -52.043 8.419 1.00 33.94 C ANISOU 439 CG GLU A 263 4139 4141 4615 -41 45 68 C ATOM 440 CD GLU A 263 31.201 -51.738 8.757 1.00 36.02 C ANISOU 440 CD GLU A 263 4598 4905 4183 -182 12 327 C ATOM 441 OE1 GLU A 263 31.656 -52.063 9.896 1.00 41.02 O ANISOU 441 OE1 GLU A 263 5021 5310 5255 219 -349 335 O ATOM 442 OE2 GLU A 263 31.909 -51.180 7.879 1.00 43.50 O ANISOU 442 OE2 GLU A 263 5311 5431 5787 -209 244 335 O ATOM 443 H GLU A 263 27.629 -50.326 11.272 1.00 21.82 H ATOM 444 HA GLU A 263 29.790 -49.862 9.895 1.00 26.25 H ATOM 445 HB2 GLU A 263 29.042 -52.076 10.333 1.00 30.01 H ATOM 446 HB3 GLU A 263 27.882 -51.850 9.269 1.00 30.01 H ATOM 447 HG2 GLU A 263 29.623 -53.000 8.286 1.00 40.74 H ATOM 448 HG3 GLU A 263 29.485 -51.569 7.605 1.00 40.74 H ATOM 449 N LEU A 264 27.111 -48.921 8.587 1.00 18.19 N ANISOU 449 N LEU A 264 1825 1794 3292 27 809 -121 N ATOM 450 CA LEU A 264 26.516 -48.235 7.461 1.00 17.63 C ANISOU 450 CA LEU A 264 2180 1633 2885 70 741 23 C ATOM 451 C LEU A 264 27.006 -46.796 7.407 1.00 20.08 C ANISOU 451 C LEU A 264 3037 1863 2730 -98 1074 -228 C ATOM 452 O LEU A 264 27.559 -46.338 6.407 1.00 22.79 O ANISOU 452 O LEU A 264 3767 2022 2869 -221 1180 -94 O ATOM 453 CB LEU A 264 24.978 -48.355 7.458 1.00 16.07 C ANISOU 453 CB LEU A 264 2009 1765 2333 472 249 67 C ATOM 454 CG LEU A 264 24.505 -49.785 7.234 1.00 16.23 C ANISOU 454 CG LEU A 264 1807 1919 2441 156 569 -226 C ATOM 455 CD1 LEU A 264 23.055 -49.973 7.562 1.00 16.87 C ANISOU 455 CD1 LEU A 264 1995 2389 2025 486 301 -63 C ATOM 456 CD2 LEU A 264 24.758 -50.224 5.813 1.00 20.11 C ANISOU 456 CD2 LEU A 264 2367 2483 2792 -326 970 -430 C ATOM 457 H LEU A 264 26.587 -48.987 9.266 1.00 21.84 H ATOM 458 HA LEU A 264 26.834 -48.672 6.643 1.00 21.17 H ATOM 459 HB2 LEU A 264 24.635 -48.055 8.314 1.00 19.30 H ATOM 460 HB3 LEU A 264 24.618 -47.804 6.745 1.00 19.30 H ATOM 461 HG LEU A 264 25.014 -50.372 7.816 1.00 19.49 H ATOM 462 HD11 LEU A 264 22.815 -50.889 7.403 1.00 20.25 H ATOM 463 HD12 LEU A 264 22.913 -49.753 8.485 1.00 20.25 H ATOM 464 HD13 LEU A 264 22.531 -49.395 7.002 1.00 20.25 H ATOM 465 HD21 LEU A 264 24.449 -51.127 5.706 1.00 24.15 H ATOM 466 HD22 LEU A 264 24.281 -49.642 5.217 1.00 24.15 H ATOM 467 HD23 LEU A 264 25.700 -50.176 5.635 1.00 24.15 H ATOM 468 N ILE A 265 26.814 -46.036 8.480 1.00 18.57 N ANISOU 468 N ILE A 265 2524 1560 2971 -173 683 22 N ATOM 469 CA ILE A 265 27.106 -44.592 8.483 1.00 19.97 C ANISOU 469 CA ILE A 265 2693 1990 2907 -287 164 499 C ATOM 470 C ILE A 265 27.743 -44.043 9.691 1.00 19.30 C ANISOU 470 C ILE A 265 2338 1991 3005 -201 569 231 C ATOM 471 O ILE A 265 27.780 -42.843 9.848 1.00 22.90 O ANISOU 471 O ILE A 265 2643 1708 4351 -431 277 28 O ATOM 472 CB ILE A 265 25.865 -43.802 8.202 1.00 17.08 C ANISOU 472 CB ILE A 265 2031 2276 2184 -216 -235 117 C ATOM 473 CG1 ILE A 265 24.706 -44.132 9.128 1.00 17.15 C ANISOU 473 CG1 ILE A 265 2028 1835 2654 93 44 70 C ATOM 474 CG2 ILE A 265 25.460 -44.017 6.814 1.00 20.52 C ANISOU 474 CG2 ILE A 265 2458 2616 2723 15 55 20 C ATOM 475 CD1 ILE A 265 23.561 -43.165 8.888 1.00 20.37 C ANISOU 475 CD1 ILE A 265 2568 2513 2660 553 -134 -167 C ATOM 476 H ILE A 265 26.511 -46.329 9.230 1.00 22.30 H ATOM 477 HA ILE A 265 27.723 -44.417 7.741 1.00 23.98 H ATOM 478 HB ILE A 265 26.077 -42.862 8.311 1.00 20.51 H ATOM 479 HG12 ILE A 265 24.393 -45.032 8.949 1.00 20.59 H ATOM 480 HG13 ILE A 265 24.993 -44.048 10.050 1.00 20.59 H ATOM 481 HG21 ILE A 265 24.664 -43.509 6.639 1.00 24.64 H ATOM 482 HG22 ILE A 265 26.168 -43.727 6.234 1.00 24.64 H ATOM 483 HG23 ILE A 265 25.288 -44.952 6.680 1.00 24.64 H ATOM 484 HD11 ILE A 265 22.837 -43.386 9.479 1.00 24.46 H ATOM 485 HD12 ILE A 265 23.865 -42.271 9.062 1.00 24.46 H ATOM 486 HD13 ILE A 265 23.273 -43.242 7.976 1.00 24.46 H ATOM 487 N GLY A 266 28.339 -44.904 10.487 1.00 19.55 N ANISOU 487 N GLY A 266 2425 1788 3215 -424 580 17 N ATOM 488 CA GLY A 266 29.349 -44.505 11.411 1.00 20.88 C ANISOU 488 CA GLY A 266 2140 2120 3673 -406 84 -89 C ATOM 489 C GLY A 266 28.913 -44.269 12.820 1.00 18.24 C ANISOU 489 C GLY A 266 1711 2055 3163 -231 -573 164 C ATOM 490 O GLY A 266 29.692 -44.449 13.749 1.00 22.99 O ANISOU 490 O GLY A 266 1416 2940 4379 234 -762 -417 O ATOM 491 H GLY A 266 28.163 -45.745 10.506 1.00 23.47 H ATOM 492 HA2 GLY A 266 30.038 -45.188 11.428 1.00 25.07 H ATOM 493 HA3 GLY A 266 29.755 -43.685 11.089 1.00 25.07 H ATOM 494 N TYR A 267 27.673 -43.896 13.060 1.00 16.99 N ANISOU 494 N TYR A 267 1152 1963 3339 -43 -505 466 N ATOM 495 CA TYR A 267 27.294 -43.555 14.411 1.00 15.69 C ANISOU 495 CA TYR A 267 1236 1785 2942 5 -598 239 C ATOM 496 C TYR A 267 27.255 -44.744 15.310 1.00 15.08 C ANISOU 496 C TYR A 267 1247 1700 2781 -109 -538 348 C ATOM 497 O TYR A 267 26.808 -45.841 14.932 1.00 15.69 O ANISOU 497 O TYR A 267 1486 1619 2857 -56 -539 102 O ATOM 498 CB TYR A 267 25.909 -42.962 14.420 1.00 15.13 C ANISOU 498 CB TYR A 267 1436 1722 2591 -55 -571 203 C ATOM 499 CG TYR A 267 25.776 -41.770 13.498 1.00 13.11 C ANISOU 499 CG TYR A 267 1236 1599 2144 60 -434 131 C ATOM 500 CD1 TYR A 267 26.392 -40.579 13.851 1.00 14.39 C ANISOU 500 CD1 TYR A 267 1586 1664 2219 -55 -258 86 C ATOM 501 CD2 TYR A 267 25.043 -41.808 12.321 1.00 14.08 C ANISOU 501 CD2 TYR A 267 1355 1809 2186 132 -379 52 C ATOM 502 CE1 TYR A 267 26.288 -39.478 13.053 1.00 14.75 C ANISOU 502 CE1 TYR A 267 1787 1535 2283 -184 -269 -40 C ATOM 503 CE2 TYR A 267 24.959 -40.687 11.473 1.00 13.76 C ANISOU 503 CE2 TYR A 267 1344 1801 2081 -90 -703 144 C ATOM 504 CZ TYR A 267 25.591 -39.524 11.876 1.00 13.11 C ANISOU 504 CZ TYR A 267 1405 1535 2042 28 -321 94 C ATOM 505 OH TYR A 267 25.536 -38.401 11.099 1.00 14.65 O ANISOU 505 OH TYR A 267 1500 1647 2418 -31 -200 145 O ATOM 506 H TYR A 267 27.046 -43.833 12.475 1.00 20.40 H ATOM 507 HA TYR A 267 27.922 -42.900 14.779 1.00 18.85 H ATOM 508 HB2 TYR A 267 25.275 -43.636 14.132 1.00 18.17 H ATOM 509 HB3 TYR A 267 25.697 -42.669 15.320 1.00 18.17 H ATOM 510 HD1 TYR A 267 26.876 -40.529 14.644 1.00 17.29 H ATOM 511 HD2 TYR A 267 24.636 -42.604 12.065 1.00 16.91 H ATOM 512 HE1 TYR A 267 26.720 -38.692 13.298 1.00 17.72 H ATOM 513 HE2 TYR A 267 24.473 -40.720 10.681 1.00 16.52 H ATOM 514 HH TYR A 267 24.757 -38.165 11.001 1.00 17.59 H ATOM 515 N HIS A 268 27.615 -44.512 16.552 1.00 17.50 N ANISOU 515 N HIS A 268 1517 2116 3016 -342 -1148 480 N ATOM 516 CA HIS A 268 27.286 -45.458 17.610 1.00 18.02 C ANISOU 516 CA HIS A 268 1926 2185 2737 -352 -727 700 C ATOM 517 C HIS A 268 25.914 -45.117 18.119 1.00 17.73 C ANISOU 517 C HIS A 268 1691 2053 2991 -136 -985 470 C ATOM 518 O HIS A 268 25.619 -43.963 18.280 1.00 17.69 O ANISOU 518 O HIS A 268 1698 1937 3087 -182 -768 288 O ATOM 519 CB HIS A 268 28.288 -45.270 18.764 1.00 21.92 C ANISOU 519 CB HIS A 268 2303 3062 2964 -130 -1289 554 C ATOM 520 CG HIS A 268 29.649 -45.759 18.426 1.00 24.12 C ANISOU 520 CG HIS A 268 2997 3327 2842 48 -972 397 C ATOM 521 ND1 HIS A 268 29.947 -47.100 18.278 1.00 30.11 N ANISOU 521 ND1 HIS A 268 3042 4267 4130 612 -406 202 N ATOM 522 CD2 HIS A 268 30.732 -45.074 18.026 1.00 27.82 C ANISOU 522 CD2 HIS A 268 3503 3756 3313 144 -1001 298 C ATOM 523 CE1 HIS A 268 31.208 -47.212 17.897 1.00 30.90 C ANISOU 523 CE1 HIS A 268 3544 3893 4304 328 -361 305 C ATOM 524 NE2 HIS A 268 31.700 -45.994 17.726 1.00 25.45 N ANISOU 524 NE2 HIS A 268 3002 3068 3600 35 -819 50 N ATOM 525 H HIS A 268 28.050 -43.819 16.815 1.00 21.01 H ATOM 526 HA HIS A 268 27.310 -46.382 17.284 1.00 21.64 H ATOM 527 HB2 HIS A 268 28.352 -44.325 18.977 1.00 26.32 H ATOM 528 HB3 HIS A 268 27.975 -45.764 19.539 1.00 26.32 H ATOM 529 HD2 HIS A 268 30.822 -44.148 17.998 1.00 33.40 H ATOM 530 HE1 HIS A 268 31.667 -48.009 17.761 1.00 37.10 H ATOM 531 N PRO A 269 25.067 -46.135 18.398 1.00 16.98 N ANISOU 531 N PRO A 269 1631 1831 2989 -26 -990 304 N ATOM 532 CA PRO A 269 23.712 -45.865 18.859 1.00 17.56 C ANISOU 532 CA PRO A 269 1824 2037 2812 -7 -1097 56 C ATOM 533 C PRO A 269 23.644 -44.862 20.012 1.00 16.87 C ANISOU 533 C PRO A 269 1886 2151 2372 -343 -1028 335 C ATOM 534 O PRO A 269 22.811 -43.968 20.034 1.00 16.91 O ANISOU 534 O PRO A 269 1773 2023 2630 -124 -530 359 O ATOM 535 CB PRO A 269 23.194 -47.213 19.234 1.00 17.89 C ANISOU 535 CB PRO A 269 2034 2058 2706 -401 -677 158 C ATOM 536 CG PRO A 269 23.837 -48.077 18.213 1.00 17.89 C ANISOU 536 CG PRO A 269 2182 2142 2475 -251 -461 124 C ATOM 537 CD PRO A 269 25.225 -47.566 18.042 1.00 18.17 C ANISOU 537 CD PRO A 269 1970 1869 3066 -34 -667 449 C ATOM 538 HA PRO A 269 23.175 -45.520 18.116 1.00 21.09 H ATOM 539 HB2 PRO A 269 23.485 -47.449 20.129 1.00 21.48 H ATOM 540 HB3 PRO A 269 22.227 -47.236 19.157 1.00 21.48 H ATOM 541 HG2 PRO A 269 23.850 -48.995 18.528 1.00 21.49 H ATOM 542 HG3 PRO A 269 23.346 -48.012 17.379 1.00 21.49 H ATOM 543 HD2 PRO A 269 25.831 -48.007 18.658 1.00 21.82 H ATOM 544 HD3 PRO A 269 25.514 -47.660 17.121 1.00 21.82 H ATOM 545 N GLU A 270 24.543 -45.010 20.952 1.00 19.98 N ANISOU 545 N GLU A 270 2551 2309 2731 -233 -1277 447 N ATOM 546 CA GLU A 270 24.483 -44.219 22.182 1.00 22.34 C ANISOU 546 CA GLU A 270 2994 2631 2863 -163 -1537 460 C ATOM 547 C GLU A 270 24.590 -42.737 21.876 1.00 19.75 C ANISOU 547 C GLU A 270 2611 2386 2508 -301 -1049 237 C ATOM 548 O GLU A 270 23.986 -41.878 22.586 1.00 21.47 O ANISOU 548 O GLU A 270 2772 2665 2722 -219 -935 16 O ATOM 549 CB GLU A 270 25.530 -44.624 23.222 1.00 28.51 C ANISOU 549 CB GLU A 270 3894 3435 3502 130 -768 439 C ATOM 550 CG GLU A 270 26.878 -44.601 22.667 1.00 33.86 C ANISOU 550 CG GLU A 270 4348 4280 4238 122 -635 255 C ATOM 551 CD GLU A 270 27.341 -45.912 21.958 1.00 39.38 C ANISOU 551 CD GLU A 270 4598 5113 5251 395 13 394 C ATOM 552 OE1 GLU A 270 26.556 -46.871 21.544 1.00 34.91 O ANISOU 552 OE1 GLU A 270 3704 5390 4170 1157 -1233 1952 O ATOM 553 OE2 GLU A 270 28.605 -45.939 21.808 1.00 43.72 O ANISOU 553 OE2 GLU A 270 4937 5706 5968 -177 -180 357 O ATOM 554 H GLU A 270 25.204 -45.559 20.915 1.00 23.99 H ATOM 555 HA GLU A 270 23.604 -44.365 22.590 1.00 26.82 H ATOM 556 HB2 GLU A 270 25.498 -44.003 23.966 1.00 34.22 H ATOM 557 HB3 GLU A 270 25.344 -45.525 23.530 1.00 34.22 H ATOM 558 HG2 GLU A 270 26.927 -43.886 22.014 1.00 40.65 H ATOM 559 HG3 GLU A 270 27.503 -44.425 23.387 1.00 40.65 H ATOM 560 N GLU A 271 25.314 -42.392 20.817 1.00 18.93 N ANISOU 560 N GLU A 271 2014 2173 3006 -273 -1333 -48 N ATOM 561 CA GLU A 271 25.481 -40.972 20.483 1.00 20.20 C ANISOU 561 CA GLU A 271 2099 2377 3199 13 -550 -427 C ATOM 562 C GLU A 271 24.282 -40.369 19.774 1.00 18.34 C ANISOU 562 C GLU A 271 1867 2109 2991 -76 -782 -231 C ATOM 563 O GLU A 271 24.188 -39.145 19.668 1.00 20.04 O ANISOU 563 O GLU A 271 2094 1776 3743 -473 -1159 -75 O ATOM 564 CB GLU A 271 26.744 -40.761 19.615 1.00 21.10 C ANISOU 564 CB GLU A 271 2267 2519 3230 -171 -865 344 C ATOM 565 CG GLU A 271 26.597 -40.955 18.149 1.00 21.43 C ANISOU 565 CG GLU A 271 2419 2472 3250 -529 -859 615 C ATOM 566 CD GLU A 271 27.957 -40.869 17.498 1.00 24.27 C ANISOU 566 CD GLU A 271 3077 2549 3595 -843 -121 204 C ATOM 567 OE1 GLU A 271 28.406 -39.728 17.302 1.00 30.99 O ANISOU 567 OE1 GLU A 271 3892 3032 4849 -1293 -8 77 O ATOM 568 OE2 GLU A 271 28.610 -41.864 17.137 1.00 23.33 O ANISOU 568 OE2 GLU A 271 2777 2656 3431 -771 -919 210 O ATOM 569 H GLU A 271 25.711 -42.939 20.286 1.00 22.73 H ATOM 570 HA GLU A 271 25.610 -40.472 21.316 1.00 24.25 H ATOM 571 HB2 GLU A 271 27.056 -39.853 19.753 1.00 25.33 H ATOM 572 HB3 GLU A 271 27.425 -41.382 19.918 1.00 25.33 H ATOM 573 HG2 GLU A 271 26.221 -41.831 17.970 1.00 25.73 H ATOM 574 HG3 GLU A 271 26.031 -40.257 17.781 1.00 25.73 H ATOM 575 N LEU A 272 23.348 -41.209 19.305 1.00 15.96 N ANISOU 575 N LEU A 272 1548 1881 2636 -422 -696 -92 N ATOM 576 CA LEU A 272 22.141 -40.697 18.656 1.00 15.15 C ANISOU 576 CA LEU A 272 1770 1600 2385 -419 -769 47 C ATOM 577 C LEU A 272 21.063 -40.397 19.623 1.00 14.93 C ANISOU 577 C LEU A 272 1894 1690 2087 -398 -887 68 C ATOM 578 O LEU A 272 20.140 -39.639 19.322 1.00 14.56 O ANISOU 578 O LEU A 272 2028 1502 2002 -441 -891 -131 O ATOM 579 CB LEU A 272 21.615 -41.719 17.691 1.00 16.72 C ANISOU 579 CB LEU A 272 2120 1594 2639 -204 -739 -156 C ATOM 580 CG LEU A 272 22.572 -42.053 16.579 1.00 18.56 C ANISOU 580 CG LEU A 272 1948 2052 3053 155 -817 -282 C ATOM 581 CD1 LEU A 272 22.047 -43.181 15.730 1.00 20.89 C ANISOU 581 CD1 LEU A 272 2257 2574 3107 322 -917 -857 C ATOM 582 CD2 LEU A 272 22.852 -40.897 15.701 1.00 20.26 C ANISOU 582 CD2 LEU A 272 2303 2527 2870 371 136 -45 C ATOM 583 H LEU A 272 23.392 -42.066 19.352 1.00 19.17 H ATOM 584 HA LEU A 272 22.355 -39.879 18.161 1.00 18.19 H ATOM 585 HB2 LEU A 272 21.426 -42.538 18.176 1.00 20.08 H ATOM 586 HB3 LEU A 272 20.800 -41.379 17.290 1.00 20.08 H ATOM 587 HG LEU A 272 23.413 -42.341 16.967 1.00 22.29 H ATOM 588 HD11 LEU A 272 22.679 -43.367 15.033 1.00 25.08 H ATOM 589 HD12 LEU A 272 21.929 -43.957 16.282 1.00 25.08 H ATOM 590 HD13 LEU A 272 21.205 -42.919 15.349 1.00 25.08 H ATOM 591 HD21 LEU A 272 23.465 -41.169 15.014 1.00 24.33 H ATOM 592 HD22 LEU A 272 22.030 -40.597 15.307 1.00 24.33 H ATOM 593 HD23 LEU A 272 23.240 -40.193 16.227 1.00 24.33 H ATOM 594 N LEU A 273 21.092 -41.027 20.784 1.00 14.91 N ANISOU 594 N LEU A 273 1726 1671 2267 -166 -840 83 N ATOM 595 CA LEU A 273 19.958 -40.918 21.683 1.00 14.88 C ANISOU 595 CA LEU A 273 1996 1589 2069 -375 -902 243 C ATOM 596 C LEU A 273 19.735 -39.518 22.112 1.00 15.77 C ANISOU 596 C LEU A 273 2357 1926 1709 -475 -1060 -92 C ATOM 597 O LEU A 273 20.686 -38.820 22.471 1.00 16.97 O ANISOU 597 O LEU A 273 2522 1930 1995 -597 -1048 -158 O ATOM 598 CB LEU A 273 20.144 -41.832 22.875 1.00 19.51 C ANISOU 598 CB LEU A 273 2520 2037 2857 -631 -972 271 C ATOM 599 CG LEU A 273 20.346 -43.320 22.542 1.00 20.12 C ANISOU 599 CG LEU A 273 2749 2009 2888 -246 -1156 596 C ATOM 600 CD1 LEU A 273 20.202 -44.173 23.809 1.00 24.67 C ANISOU 600 CD1 LEU A 273 3174 2609 3590 -305 -432 940 C ATOM 601 CD2 LEU A 273 19.349 -43.897 21.500 1.00 21.35 C ANISOU 601 CD2 LEU A 273 2375 2377 3359 -660 -1031 88 C ATOM 602 H LEU A 273 21.740 -41.513 21.071 1.00 17.90 H ATOM 603 HA LEU A 273 19.154 -41.213 21.207 1.00 17.87 H ATOM 604 HB2 LEU A 273 20.924 -41.536 23.370 1.00 23.43 H ATOM 605 HB3 LEU A 273 19.358 -41.764 23.440 1.00 23.43 H ATOM 606 HG LEU A 273 21.244 -43.446 22.198 1.00 24.16 H ATOM 607 HD11 LEU A 273 20.331 -45.096 23.581 1.00 29.62 H ATOM 608 HD12 LEU A 273 20.864 -43.898 24.448 1.00 29.62 H ATOM 609 HD13 LEU A 273 19.323 -44.045 24.173 1.00 29.62 H ATOM 610 HD21 LEU A 273 19.550 -44.825 21.356 1.00 25.63 H ATOM 611 HD22 LEU A 273 18.455 -43.804 21.838 1.00 25.63 H ATOM 612 HD23 LEU A 273 19.441 -43.411 20.677 1.00 25.63 H ATOM 613 N GLY A 274 18.503 -39.085 22.049 1.00 14.93 N ANISOU 613 N GLY A 274 2340 1642 1691 -472 -902 175 N ATOM 614 CA GLY A 274 18.112 -37.729 22.421 1.00 15.54 C ANISOU 614 CA GLY A 274 2778 1595 1531 -376 -616 -171 C ATOM 615 C GLY A 274 18.264 -36.730 21.311 1.00 17.15 C ANISOU 615 C GLY A 274 3262 1252 2002 -409 -1111 -371 C ATOM 616 O GLY A 274 17.889 -35.570 21.494 1.00 20.23 O ANISOU 616 O GLY A 274 3892 1370 2424 -310 -838 -258 O ATOM 617 H GLY A 274 17.843 -39.568 21.785 1.00 17.93 H ATOM 618 HA2 GLY A 274 17.183 -37.731 22.701 1.00 18.66 H ATOM 619 HA3 GLY A 274 18.654 -37.435 23.169 1.00 18.66 H ATOM 620 N ARG A 275 18.823 -37.106 20.156 1.00 15.48 N ANISOU 620 N ARG A 275 2915 1292 1674 -350 -1122 -56 N ATOM 621 CA ARG A 275 18.919 -36.204 19.032 1.00 16.06 C ANISOU 621 CA ARG A 275 2687 1398 2019 -419 -1092 -175 C ATOM 622 C ARG A 275 17.741 -36.491 18.108 1.00 12.00 C ANISOU 622 C ARG A 275 1954 1103 1501 -158 -534 -102 C ATOM 623 O ARG A 275 17.358 -37.624 17.857 1.00 10.82 O ANISOU 623 O ARG A 275 1549 1003 1560 -232 -421 -64 O ATOM 624 CB ARG A 275 20.207 -36.451 18.280 1.00 16.74 C ANISOU 624 CB ARG A 275 2392 1907 2061 -750 -1349 185 C ATOM 625 CG ARG A 275 21.488 -36.121 19.088 1.00 20.72 C ANISOU 625 CG ARG A 275 2762 2182 2928 -835 -1040 500 C ATOM 626 CD ARG A 275 22.828 -36.137 18.244 1.00 23.45 C ANISOU 626 CD ARG A 275 2833 2867 3210 -617 -1505 598 C ATOM 627 NE ARG A 275 22.814 -35.319 17.056 1.00 24.19 N ANISOU 627 NE ARG A 275 2999 2737 3455 -535 -702 369 N ATOM 628 CZ ARG A 275 23.757 -35.263 16.091 1.00 27.14 C ANISOU 628 CZ ARG A 275 3595 3037 3680 208 -197 1053 C ATOM 629 NH1 ARG A 275 24.820 -36.053 16.118 1.00 33.40 N ANISOU 629 NH1 ARG A 275 3876 4269 4547 -237 42 684 N ATOM 630 NH2 ARG A 275 23.563 -34.474 15.041 1.00 31.57 N ANISOU 630 NH2 ARG A 275 4002 3922 4070 565 -298 1573 N ATOM 631 H ARG A 275 19.153 -37.887 20.008 1.00 18.59 H ATOM 632 HA ARG A 275 18.884 -35.272 19.331 1.00 19.29 H ATOM 633 HB2 ARG A 275 20.248 -37.388 18.032 1.00 20.10 H ATOM 634 HB3 ARG A 275 20.212 -35.900 17.482 1.00 20.10 H ATOM 635 HG2 ARG A 275 21.393 -35.235 19.470 1.00 24.88 H ATOM 636 HG3 ARG A 275 21.582 -36.775 19.798 1.00 24.88 H ATOM 637 HD2 ARG A 275 23.550 -35.820 18.809 1.00 28.16 H ATOM 638 HD3 ARG A 275 23.007 -37.049 17.969 1.00 28.16 H ATOM 639 HE ARG A 275 22.042 -34.745 16.937 1.00 29.04 H ATOM 640 HH11 ARG A 275 24.946 -36.581 16.785 1.00 40.10 H ATOM 641 HH12 ARG A 275 25.403 -36.011 15.487 1.00 40.10 H ATOM 642 HH21 ARG A 275 22.871 -33.964 15.009 1.00 37.89 H ATOM 643 HH22 ARG A 275 24.154 -34.436 14.418 1.00 37.89 H ATOM 644 N SER A 276 17.202 -35.429 17.530 1.00 14.83 N ANISOU 644 N SER A 276 2941 1156 1536 -330 -861 -150 N ATOM 645 CA SER A 276 16.124 -35.566 16.545 1.00 13.09 C ANISOU 645 CA SER A 276 2338 1258 1377 -119 -355 -82 C ATOM 646 C SER A 276 16.628 -36.132 15.221 1.00 10.85 C ANISOU 646 C SER A 276 1538 1112 1473 -123 -446 -34 C ATOM 647 O SER A 276 17.653 -35.679 14.746 1.00 11.06 O ANISOU 647 O SER A 276 1380 1095 1727 -196 -556 85 O ATOM 648 CB SER A 276 15.544 -34.171 16.311 1.00 15.89 C ANISOU 648 CB SER A 276 2692 1632 1714 556 -305 -295 C ATOM 649 OG SER A 276 14.618 -34.264 15.293 1.00 16.47 O ANISOU 649 OG SER A 276 2745 1941 1573 810 -284 -208 O ATOM 650 H SER A 276 17.436 -34.617 17.687 1.00 17.81 H ATOM 651 HA SER A 276 15.420 -36.150 16.896 1.00 15.72 H ATOM 652 HB2 SER A 276 15.108 -33.860 17.119 1.00 19.08 H ATOM 653 HB3 SER A 276 16.254 -33.563 16.050 1.00 19.08 H ATOM 654 HG SER A 276 14.289 -33.528 15.145 1.00 19.78 H ATOM 655 N ALA A 277 15.875 -37.022 14.601 1.00 10.47 N ANISOU 655 N ALA A 277 1374 1176 1429 -78 -198 -118 N ATOM 656 CA ALA A 277 16.189 -37.472 13.265 1.00 9.62 C ANISOU 656 CA ALA A 277 1010 1139 1505 -195 -166 -78 C ATOM 657 C ALA A 277 16.328 -36.316 12.319 1.00 9.30 C ANISOU 657 C ALA A 277 964 1001 1569 -222 -133 -183 C ATOM 658 O ALA A 277 17.073 -36.401 11.340 1.00 9.96 O ANISOU 658 O ALA A 277 1094 1069 1619 -160 -32 -266 O ATOM 659 CB ALA A 277 15.162 -38.473 12.767 1.00 11.63 C ANISOU 659 CB ALA A 277 1354 1335 1729 -359 -108 -153 C ATOM 660 H ALA A 277 15.171 -37.383 14.938 1.00 12.58 H ATOM 661 HA ALA A 277 17.054 -37.931 13.291 1.00 11.55 H ATOM 662 HB1 ALA A 277 15.401 -38.750 11.879 1.00 13.97 H ATOM 663 HB2 ALA A 277 15.155 -39.231 13.356 1.00 13.97 H ATOM 664 HB3 ALA A 277 14.298 -38.056 12.759 1.00 13.97 H ATOM 665 N TYR A 278 15.598 -35.225 12.545 1.00 9.07 N ANISOU 665 N TYR A 278 957 1097 1395 -91 -76 -43 N ATOM 666 CA TYR A 278 15.675 -34.082 11.684 1.00 8.71 C ANISOU 666 CA TYR A 278 948 1086 1274 -74 -160 -107 C ATOM 667 C TYR A 278 17.075 -33.473 11.586 1.00 9.26 C ANISOU 667 C TYR A 278 1261 1036 1220 19 -157 -81 C ATOM 668 O TYR A 278 17.394 -32.838 10.573 1.00 11.10 O ANISOU 668 O TYR A 278 1204 1413 1599 -31 -113 220 O ATOM 669 CB TYR A 278 14.694 -33.014 12.111 1.00 9.47 C ANISOU 669 CB TYR A 278 1039 1292 1268 -39 -152 39 C ATOM 670 CG TYR A 278 13.258 -33.335 11.823 1.00 9.35 C ANISOU 670 CG TYR A 278 1139 1144 1270 -50 -171 33 C ATOM 671 CD1 TYR A 278 12.461 -33.900 12.773 1.00 11.48 C ANISOU 671 CD1 TYR A 278 1290 1462 1612 -177 -322 417 C ATOM 672 CD2 TYR A 278 12.715 -33.045 10.568 1.00 10.53 C ANISOU 672 CD2 TYR A 278 1321 1237 1444 -96 -166 -134 C ATOM 673 CE1 TYR A 278 11.102 -34.184 12.499 1.00 13.27 C ANISOU 673 CE1 TYR A 278 1238 1896 1907 -195 -286 181 C ATOM 674 CE2 TYR A 278 11.366 -33.279 10.298 1.00 12.58 C ANISOU 674 CE2 TYR A 278 1192 1597 1989 -447 -177 226 C ATOM 675 CZ TYR A 278 10.576 -33.858 11.270 1.00 13.03 C ANISOU 675 CZ TYR A 278 1121 1662 2167 -344 -755 136 C ATOM 676 OH TYR A 278 9.238 -34.016 11.043 1.00 17.51 O ANISOU 676 OH TYR A 278 1567 2747 2340 -777 -620 646 O ATOM 677 H TYR A 278 15.050 -35.135 13.201 1.00 10.90 H ATOM 678 HA TYR A 278 15.420 -34.365 10.780 1.00 10.46 H ATOM 679 HB2 TYR A 278 14.778 -32.881 13.068 1.00 11.38 H ATOM 680 HB3 TYR A 278 14.910 -32.191 11.646 1.00 11.38 H ATOM 681 HD1 TYR A 278 12.816 -34.108 13.608 1.00 13.79 H ATOM 682 HD2 TYR A 278 13.246 -32.636 9.923 1.00 12.65 H ATOM 683 HE1 TYR A 278 10.554 -34.532 13.164 1.00 15.93 H ATOM 684 HE2 TYR A 278 11.006 -33.052 9.472 1.00 15.11 H ATOM 685 HH TYR A 278 8.808 -33.556 11.568 1.00 21.03 H ATOM 686 N AGLU A 279 17.920 -33.615 12.596 0.54 9.36 N ANISOU 686 N AGLU A 279 1132 940 1485 -301 -238 -97 N ATOM 687 N BGLU A 279 17.915 -33.758 12.584 0.46 8.73 N ANISOU 687 N BGLU A 279 1010 1171 1135 -14 -217 -127 N ATOM 688 CA AGLU A 279 19.288 -33.118 12.464 0.54 9.04 C ANISOU 688 CA AGLU A 279 983 742 1710 -264 -271 -288 C ATOM 689 CA BGLU A 279 19.270 -33.221 12.646 0.46 10.63 C ANISOU 689 CA BGLU A 279 1179 1084 1776 -75 -268 -133 C ATOM 690 C AGLU A 279 20.055 -33.755 11.316 0.54 8.86 C ANISOU 690 C AGLU A 279 721 771 1875 -87 -307 -399 C ATOM 691 C BGLU A 279 20.165 -33.909 11.603 0.46 10.95 C ANISOU 691 C BGLU A 279 1384 1026 1750 -61 -220 -130 C ATOM 692 O AGLU A 279 21.094 -33.222 10.869 0.54 10.03 O ANISOU 692 O AGLU A 279 701 882 2227 -305 -219 -34 O ATOM 693 O BGLU A 279 21.323 -33.485 11.384 0.46 11.66 O ANISOU 693 O BGLU A 279 1532 992 1905 21 -525 -144 O ATOM 694 CB AGLU A 279 20.051 -33.348 13.748 0.54 11.37 C ANISOU 694 CB AGLU A 279 1624 1094 1600 -13 -349 -101 C ATOM 695 CB BGLU A 279 19.834 -33.342 14.072 0.46 11.92 C ANISOU 695 CB BGLU A 279 1304 1642 1583 -602 -1 -187 C ATOM 696 CG AGLU A 279 19.473 -32.606 14.881 0.54 11.05 C ANISOU 696 CG AGLU A 279 1567 1071 1561 -43 -460 -445 C ATOM 697 CG BGLU A 279 19.141 -32.421 15.093 0.46 13.39 C ANISOU 697 CG BGLU A 279 1902 1880 1307 -113 131 -219 C ATOM 698 CD AGLU A 279 20.093 -33.019 16.188 0.54 12.15 C ANISOU 698 CD AGLU A 279 1587 1327 1703 172 5 -86 C ATOM 699 CD BGLU A 279 19.790 -32.425 16.492 0.46 15.19 C ANISOU 699 CD BGLU A 279 2094 1976 1701 0 124 -83 C ATOM 700 OE1AGLU A 279 19.349 -33.137 17.164 0.54 13.80 O ANISOU 700 OE1AGLU A 279 2116 1391 1738 -2 -208 -30 O ATOM 701 OE1BGLU A 279 20.772 -33.143 16.702 0.46 16.84 O ANISOU 701 OE1BGLU A 279 2272 2150 1977 -135 -175 10 O ATOM 702 OE2AGLU A 279 21.312 -33.234 16.222 0.54 11.38 O ANISOU 702 OE2AGLU A 279 1349 1264 1710 -341 -114 114 O ATOM 703 OE2BGLU A 279 19.324 -31.731 17.412 0.46 16.31 O ANISOU 703 OE2BGLU A 279 2294 2247 1657 -647 284 -708 O ATOM 704 H AGLU A 279 17.738 -33.985 13.351 0.54 11.25 H ATOM 705 H BGLU A 279 17.716 -34.269 13.247 0.46 10.49 H ATOM 706 HA AGLU A 279 19.258 -32.152 12.303 0.54 10.86 H ATOM 707 HA BGLU A 279 19.237 -32.268 12.422 0.46 12.77 H ATOM 708 HB2AGLU A 279 20.031 -34.294 13.964 0.54 13.65 H ATOM 709 HB2BGLU A 279 19.724 -34.257 14.375 0.46 14.32 H ATOM 710 HB3AGLU A 279 20.968 -33.053 13.630 0.54 13.65 H ATOM 711 HB3BGLU A 279 20.776 -33.112 14.056 0.46 14.32 H ATOM 712 HG2AGLU A 279 19.631 -31.657 14.756 0.54 13.28 H ATOM 713 HG2BGLU A 279 19.166 -31.511 14.758 0.46 16.09 H ATOM 714 HG3AGLU A 279 18.520 -32.784 14.928 0.54 13.28 H ATOM 715 HG3BGLU A 279 18.219 -32.707 15.194 0.46 16.09 H ATOM 716 N PHE A 280 19.645 -34.969 10.972 1.00 9.11 N ANISOU 716 N PHE A 280 946 929 1585 -116 -5 -217 N ATOM 717 CA PHE A 280 20.395 -35.790 10.038 1.00 10.15 C ANISOU 717 CA PHE A 280 985 920 1950 -116 -298 -88 C ATOM 718 C PHE A 280 19.824 -35.795 8.625 1.00 9.93 C ANISOU 718 C PHE A 280 1065 1123 1584 -109 140 -170 C ATOM 719 O PHE A 280 20.443 -36.376 7.738 1.00 13.43 O ANISOU 719 O PHE A 280 1322 1704 2075 330 108 -461 O ATOM 720 CB PHE A 280 20.466 -37.256 10.568 1.00 11.18 C ANISOU 720 CB PHE A 280 1061 1053 2134 -76 -232 -130 C ATOM 721 CG PHE A 280 20.990 -37.387 11.977 1.00 11.75 C ANISOU 721 CG PHE A 280 1164 1104 2196 214 -308 -119 C ATOM 722 CD1 PHE A 280 22.334 -37.536 12.195 1.00 18.39 C ANISOU 722 CD1 PHE A 280 1973 2409 2604 792 27 600 C ATOM 723 CD2 PHE A 280 20.159 -37.292 13.088 1.00 12.69 C ANISOU 723 CD2 PHE A 280 1422 1249 2151 17 -62 82 C ATOM 724 CE1 PHE A 280 22.837 -37.646 13.531 1.00 20.78 C ANISOU 724 CE1 PHE A 280 1744 3112 3040 733 -811 449 C ATOM 725 CE2 PHE A 280 20.648 -37.401 14.362 1.00 13.71 C ANISOU 725 CE2 PHE A 280 1655 1516 2037 106 -363 158 C ATOM 726 CZ PHE A 280 21.953 -37.601 14.599 1.00 19.41 C ANISOU 726 CZ PHE A 280 2292 2549 2533 671 -253 432 C ATOM 727 H APHE A 280 18.929 -35.341 11.269 0.54 10.94 H ATOM 728 H BPHE A 280 18.834 -35.233 11.078 0.46 10.94 H ATOM 729 HA PHE A 280 21.311 -35.448 9.986 1.00 12.19 H ATOM 730 HB2 PHE A 280 19.573 -37.636 10.550 1.00 13.43 H ATOM 731 HB3 PHE A 280 21.051 -37.768 9.988 1.00 13.43 H ATOM 732 HD1 PHE A 280 22.917 -37.594 11.473 1.00 22.08 H ATOM 733 HD2 PHE A 280 19.244 -37.184 12.962 1.00 15.24 H ATOM 734 HE1 PHE A 280 23.746 -37.775 13.680 1.00 24.95 H ATOM 735 HE2 PHE A 280 20.058 -37.360 15.079 1.00 16.46 H ATOM 736 HZ PHE A 280 22.268 -37.651 15.472 1.00 23.31 H ATOM 737 N TYR A 281 18.677 -35.191 8.392 1.00 9.78 N ANISOU 737 N TYR A 281 1174 1180 1360 -58 -2 86 N ATOM 738 CA TYR A 281 18.129 -35.180 7.089 1.00 9.57 C ANISOU 738 CA TYR A 281 1261 974 1402 -184 -109 89 C ATOM 739 C TYR A 281 18.798 -34.121 6.228 1.00 9.37 C ANISOU 739 C TYR A 281 1392 1069 1099 -148 -24 -57 C ATOM 740 O TYR A 281 19.004 -33.001 6.669 1.00 10.65 O ANISOU 740 O TYR A 281 1705 1018 1323 -176 79 -112 O ATOM 741 CB TYR A 281 16.640 -34.851 7.081 1.00 10.16 C ANISOU 741 CB TYR A 281 1238 1182 1440 -85 -52 87 C ATOM 742 CG TYR A 281 15.733 -35.797 7.866 1.00 10.07 C ANISOU 742 CG TYR A 281 1381 1188 1258 -172 -232 -83 C ATOM 743 CD1 TYR A 281 16.019 -37.165 7.984 1.00 11.18 C ANISOU 743 CD1 TYR A 281 1363 1369 1517 -27 260 -21 C ATOM 744 CD2 TYR A 281 14.571 -35.352 8.471 1.00 10.15 C ANISOU 744 CD2 TYR A 281 1209 1105 1541 -128 -197 -10 C ATOM 745 CE1 TYR A 281 15.167 -38.017 8.711 1.00 11.32 C ANISOU 745 CE1 TYR A 281 1620 1273 1409 -198 195 -11 C ATOM 746 CE2 TYR A 281 13.752 -36.181 9.163 1.00 9.99 C ANISOU 746 CE2 TYR A 281 1290 1210 1297 -195 -199 -283 C ATOM 747 CZ TYR A 281 14.018 -37.507 9.257 1.00 10.32 C ANISOU 747 CZ TYR A 281 1455 1350 1115 -429 221 -195 C ATOM 748 OH TYR A 281 13.119 -38.350 9.904 1.00 11.31 O ANISOU 748 OH TYR A 281 1464 1592 1242 -397 27 -83 O ATOM 749 H TYR A 281 18.206 -34.781 8.984 1.00 11.74 H ATOM 750 HA TYR A 281 18.260 -36.056 6.669 1.00 11.50 H ATOM 751 HB2 TYR A 281 16.522 -33.964 7.455 1.00 12.20 H ATOM 752 HB3 TYR A 281 16.332 -34.855 6.161 1.00 12.20 H ATOM 753 HD1 TYR A 281 16.790 -37.509 7.594 1.00 13.43 H ATOM 754 HD2 TYR A 281 14.347 -34.451 8.405 1.00 12.19 H ATOM 755 HE1 TYR A 281 15.344 -38.929 8.759 1.00 13.60 H ATOM 756 HE2 TYR A 281 12.964 -35.846 9.527 1.00 12.01 H ATOM 757 HH TYR A 281 13.487 -38.718 10.538 1.00 13.59 H ATOM 758 N HIS A 282 19.062 -34.464 4.977 1.00 10.35 N ANISOU 758 N HIS A 282 1535 1009 1390 -130 -93 -76 N ATOM 759 CA HIS A 282 19.530 -33.493 4.019 1.00 9.92 C ANISOU 759 CA HIS A 282 1526 1104 1139 -111 175 -57 C ATOM 760 C HIS A 282 18.596 -32.307 3.952 1.00 9.70 C ANISOU 760 C HIS A 282 1363 1109 1213 -115 124 35 C ATOM 761 O HIS A 282 17.367 -32.471 3.979 1.00 10.25 O ANISOU 761 O HIS A 282 1437 1211 1248 -97 14 -12 O ATOM 762 CB HIS A 282 19.717 -34.144 2.653 1.00 11.22 C ANISOU 762 CB HIS A 282 1597 1221 1445 -85 298 -111 C ATOM 763 CG HIS A 282 20.564 -33.364 1.704 1.00 11.66 C ANISOU 763 CG HIS A 282 1708 1145 1577 65 290 -117 C ATOM 764 ND1 HIS A 282 20.113 -32.233 1.041 1.00 12.68 N ANISOU 764 ND1 HIS A 282 1820 1505 1495 196 397 -97 N ATOM 765 CD2 HIS A 282 21.825 -33.584 1.288 1.00 13.64 C ANISOU 765 CD2 HIS A 282 1785 1607 1789 16 350 115 C ATOM 766 CE1 HIS A 282 21.094 -31.805 0.278 1.00 13.72 C ANISOU 766 CE1 HIS A 282 1754 1614 1845 193 673 5 C ATOM 767 NE2 HIS A 282 22.152 -32.568 0.444 1.00 14.52 N ANISOU 767 NE2 HIS A 282 2047 1825 1646 -44 768 128 N ATOM 768 H HIS A 282 18.977 -35.259 4.661 1.00 12.44 H ATOM 769 HA HIS A 282 20.405 -33.163 4.312 1.00 11.92 H ATOM 770 HB2 HIS A 282 20.137 -35.010 2.777 1.00 13.48 H ATOM 771 HB3 HIS A 282 18.846 -34.260 2.242 1.00 13.48 H ATOM 772 HD2 HIS A 282 22.391 -34.261 1.581 1.00 16.38 H ATOM 773 HE1 HIS A 282 21.061 -31.047 -0.260 1.00 16.48 H ATOM 774 N ALA A 283 19.133 -31.105 3.741 1.00 9.67 N ANISOU 774 N ALA A 283 1398 1075 1202 -29 228 64 N ATOM 775 CA ALA A 283 18.331 -29.912 3.587 1.00 9.86 C ANISOU 775 CA ALA A 283 1593 987 1165 10 111 19 C ATOM 776 C ALA A 283 17.264 -30.094 2.542 1.00 9.77 C ANISOU 776 C ALA A 283 1607 1062 1042 -44 150 70 C ATOM 777 O ALA A 283 16.141 -29.603 2.715 1.00 10.72 O ANISOU 777 O ALA A 283 1689 1147 1235 24 4 31 O ATOM 778 CB ALA A 283 19.184 -28.727 3.233 1.00 11.67 C ANISOU 778 CB ALA A 283 1791 1261 1383 -75 46 -48 C ATOM 779 H ALA A 283 19.979 -30.961 3.682 1.00 11.62 H ATOM 780 HA ALA A 283 17.887 -29.719 4.439 1.00 11.84 H ATOM 781 HB1 ALA A 283 18.622 -27.955 3.139 1.00 14.02 H ATOM 782 HB2 ALA A 283 19.825 -28.583 3.933 1.00 14.02 H ATOM 783 HB3 ALA A 283 19.638 -28.905 2.406 1.00 14.02 H ATOM 784 N LEU A 284 17.584 -30.741 1.417 1.00 10.47 N ANISOU 784 N LEU A 284 1756 1101 1121 60 -76 139 N ATOM 785 CA LEU A 284 16.618 -30.843 0.324 1.00 11.93 C ANISOU 785 CA LEU A 284 2011 1425 1097 60 -62 113 C ATOM 786 C LEU A 284 15.529 -31.830 0.551 1.00 11.45 C ANISOU 786 C LEU A 284 2048 1108 1195 -138 -70 -26 C ATOM 787 O LEU A 284 14.571 -31.876 -0.216 1.00 13.69 O ANISOU 787 O LEU A 284 2421 1469 1312 -47 -371 -39 O ATOM 788 CB LEU A 284 17.349 -31.114 -0.977 1.00 13.92 C ANISOU 788 CB LEU A 284 2363 1674 1252 -117 39 -141 C ATOM 789 CG LEU A 284 18.351 -30.010 -1.386 1.00 16.69 C ANISOU 789 CG LEU A 284 2968 2145 1226 -135 520 31 C ATOM 790 CD1 LEU A 284 19.148 -30.376 -2.682 1.00 21.04 C ANISOU 790 CD1 LEU A 284 3150 2967 1877 -96 744 32 C ATOM 791 CD2 LEU A 284 17.633 -28.653 -1.584 1.00 20.94 C ANISOU 791 CD2 LEU A 284 3040 2262 2655 -183 349 513 C ATOM 792 H LEU A 284 18.340 -31.121 1.265 1.00 12.58 H ATOM 793 HA LEU A 284 16.186 -29.968 0.228 1.00 14.33 H ATOM 794 HB2 LEU A 284 17.844 -31.943 -0.888 1.00 16.72 H ATOM 795 HB3 LEU A 284 16.695 -31.198 -1.689 1.00 16.72 H ATOM 796 HG LEU A 284 18.995 -29.897 -0.669 1.00 20.04 H ATOM 797 HD11 LEU A 284 19.752 -29.660 -2.890 1.00 25.26 H ATOM 798 HD12 LEU A 284 19.640 -31.186 -2.528 1.00 25.26 H ATOM 799 HD13 LEU A 284 18.528 -30.502 -3.404 1.00 25.26 H ATOM 800 HD21 LEU A 284 18.280 -27.991 -1.837 1.00 25.15 H ATOM 801 HD22 LEU A 284 16.973 -28.747 -2.275 1.00 25.15 H ATOM 802 HD23 LEU A 284 17.210 -28.401 -0.760 1.00 25.15 H ATOM 803 N ASP A 285 15.632 -32.621 1.627 1.00 10.60 N ANISOU 803 N ASP A 285 1571 1065 1392 -73 -214 -83 N ATOM 804 CA ASP A 285 14.598 -33.581 1.995 1.00 10.71 C ANISOU 804 CA ASP A 285 1648 1129 1292 48 -31 -128 C ATOM 805 C ASP A 285 13.822 -33.143 3.215 1.00 10.32 C ANISOU 805 C ASP A 285 1544 1091 1285 -16 -170 -85 C ATOM 806 O ASP A 285 12.938 -33.857 3.637 1.00 11.70 O ANISOU 806 O ASP A 285 1463 1309 1675 -201 -122 -91 O ATOM 807 CB ASP A 285 15.218 -34.955 2.242 1.00 11.65 C ANISOU 807 CB ASP A 285 1616 1089 1719 0 -38 -134 C ATOM 808 CG ASP A 285 15.940 -35.476 1.006 1.00 13.49 C ANISOU 808 CG ASP A 285 1992 1205 1929 124 -313 -46 C ATOM 809 OD1 ASP A 285 15.378 -35.271 -0.121 1.00 17.21 O ANISOU 809 OD1 ASP A 285 2501 1893 2143 469 -295 -542 O ATOM 810 OD2 ASP A 285 17.037 -36.015 1.125 1.00 13.37 O ANISOU 810 OD2 ASP A 285 1969 1225 1887 83 72 82 O ATOM 811 H ASP A 285 16.303 -32.616 2.164 1.00 12.74 H ATOM 812 HA ASP A 285 13.966 -33.666 1.251 1.00 12.87 H ATOM 813 HB2 ASP A 285 15.861 -34.890 2.965 1.00 13.99 H ATOM 814 HB3 ASP A 285 14.517 -35.585 2.472 1.00 13.99 H ATOM 815 N SER A 286 14.138 -31.995 3.778 1.00 10.47 N ANISOU 815 N SER A 286 1456 1201 1321 -74 33 -261 N ATOM 816 CA SER A 286 13.616 -31.653 5.096 1.00 11.80 C ANISOU 816 CA SER A 286 1590 1361 1532 -86 153 -140 C ATOM 817 C SER A 286 12.112 -31.411 5.062 1.00 10.95 C ANISOU 817 C SER A 286 1476 1248 1436 -152 204 -139 C ATOM 818 O SER A 286 11.384 -31.904 5.910 1.00 11.69 O ANISOU 818 O SER A 286 1466 1596 1378 -19 -76 -155 O ATOM 819 CB SER A 286 14.376 -30.484 5.665 1.00 12.40 C ANISOU 819 CB SER A 286 1439 1733 1541 -31 36 -443 C ATOM 820 OG SER A 286 15.696 -30.888 6.066 1.00 16.06 O ANISOU 820 OG SER A 286 2206 1814 2080 -351 230 -299 O ATOM 821 H SER A 286 14.647 -31.397 3.427 1.00 12.58 H ATOM 822 HA SER A 286 13.771 -32.416 5.692 1.00 14.17 H ATOM 823 HB2 SER A 286 14.448 -29.793 4.988 1.00 14.90 H ATOM 824 HB3 SER A 286 13.901 -30.144 6.439 1.00 14.90 H ATOM 825 HG SER A 286 15.803 -31.686 5.914 1.00 19.28 H ATOM 826 N GLU A 287 11.640 -30.635 4.081 1.00 11.64 N ANISOU 826 N GLU A 287 1393 1413 1618 -127 -2 -49 N ATOM 827 CA GLU A 287 10.203 -30.364 4.026 1.00 13.29 C ANISOU 827 CA GLU A 287 1438 1436 2176 -6 -240 20 C ATOM 828 C GLU A 287 9.413 -31.654 3.744 1.00 11.92 C ANISOU 828 C GLU A 287 1231 1558 1740 150 -433 82 C ATOM 829 O GLU A 287 8.380 -31.897 4.356 1.00 12.85 O ANISOU 829 O GLU A 287 1378 1675 1829 12 -196 -82 O ATOM 830 CB GLU A 287 9.935 -29.280 2.961 1.00 15.07 C ANISOU 830 CB GLU A 287 1830 1503 2392 99 -393 164 C ATOM 831 CG GLU A 287 10.449 -27.893 3.397 1.00 17.25 C ANISOU 831 CG GLU A 287 2307 1572 2677 213 -216 91 C ATOM 832 CD GLU A 287 9.729 -27.391 4.593 1.00 21.32 C ANISOU 832 CD GLU A 287 2811 1811 3480 -35 -437 -485 C ATOM 833 OE1 GLU A 287 8.490 -27.250 4.473 1.00 24.10 O ANISOU 833 OE1 GLU A 287 2764 2409 3984 -241 204 -777 O ATOM 834 OE2 GLU A 287 10.421 -27.061 5.614 1.00 21.94 O ANISOU 834 OE2 GLU A 287 3508 2119 2708 35 141 -234 O ATOM 835 H GLU A 287 12.110 -30.269 3.461 1.00 13.99 H ATOM 836 HA GLU A 287 9.911 -30.014 4.893 1.00 15.96 H ATOM 837 HB2 GLU A 287 10.388 -29.524 2.139 1.00 18.10 H ATOM 838 HB3 GLU A 287 8.980 -29.214 2.809 1.00 18.10 H ATOM 839 HG2 GLU A 287 11.392 -27.955 3.615 1.00 20.72 H ATOM 840 HG3 GLU A 287 10.313 -27.260 2.674 1.00 20.72 H ATOM 841 N ASN A 288 9.947 -32.510 2.866 1.00 12.17 N ANISOU 841 N ASN A 288 1538 1507 1580 -60 -389 58 N ATOM 842 CA ASN A 288 9.267 -33.786 2.618 1.00 12.16 C ANISOU 842 CA ASN A 288 1442 1626 1551 -32 -325 -16 C ATOM 843 C ASN A 288 9.194 -34.692 3.826 1.00 11.33 C ANISOU 843 C ASN A 288 1256 1582 1465 -64 -420 -188 C ATOM 844 O ASN A 288 8.208 -35.367 4.049 1.00 12.67 O ANISOU 844 O ASN A 288 1423 1691 1701 -194 -481 -81 O ATOM 845 CB ASN A 288 9.901 -34.508 1.404 1.00 15.69 C ANISOU 845 CB ASN A 288 2140 2037 1784 -251 -472 -228 C ATOM 846 CG ASN A 288 9.555 -33.816 0.081 1.00 19.89 C ANISOU 846 CG ASN A 288 2929 2594 2033 -295 -509 -485 C ATOM 847 OD1 ASN A 288 8.519 -33.146 -0.002 1.00 22.40 O ANISOU 847 OD1 ASN A 288 3575 3018 1917 -7 -707 -36 O ATOM 848 ND2 ASN A 288 10.398 -33.956 -0.929 1.00 22.59 N ANISOU 848 ND2 ASN A 288 3390 2897 2296 -432 -382 -97 N ATOM 849 H ASN A 288 10.671 -32.384 2.418 1.00 14.62 H ATOM 850 HA ASN A 288 8.342 -33.582 2.368 1.00 14.60 H ATOM 851 HB2 ASN A 288 10.866 -34.508 1.502 1.00 18.84 H ATOM 852 HB3 ASN A 288 9.569 -35.418 1.365 1.00 18.84 H ATOM 853 HD21 ASN A 288 10.208 -33.527 -1.789 1.00 27.12 H ATOM 854 HD22 ASN A 288 11.213 -34.488 -0.816 1.00 27.12 H ATOM 855 N MET A 289 10.274 -34.754 4.574 1.00 10.71 N ANISOU 855 N MET A 289 1194 1385 1490 -51 -309 -69 N ATOM 856 CA MET A 289 10.310 -35.594 5.764 1.00 10.16 C ANISOU 856 CA MET A 289 1225 1211 1424 30 -237 -136 C ATOM 857 C MET A 289 9.414 -35.021 6.854 1.00 11.28 C ANISOU 857 C MET A 289 1406 1221 1657 -9 -284 22 C ATOM 858 O MET A 289 8.824 -35.782 7.625 1.00 12.84 O ANISOU 858 O MET A 289 1714 1431 1735 20 -18 -20 O ATOM 859 CB MET A 289 11.715 -35.788 6.242 1.00 11.29 C ANISOU 859 CB MET A 289 1159 1497 1635 -36 -247 4 C ATOM 860 CG MET A 289 12.538 -36.648 5.318 1.00 13.76 C ANISOU 860 CG MET A 289 1174 1800 2255 92 102 373 C ATOM 861 SD MET A 289 11.878 -38.277 4.948 1.00 13.95 S ANISOU 861 SD MET A 289 1945 1645 1710 248 -143 -221 S ATOM 862 CE MET A 289 12.103 -39.120 6.470 1.00 14.97 C ANISOU 862 CE MET A 289 1884 1785 2018 96 -89 -98 C ATOM 863 H MET A 289 11.002 -34.322 4.421 1.00 12.87 H ATOM 864 HA MET A 289 9.965 -36.479 5.522 1.00 12.21 H ATOM 865 HB2 MET A 289 12.147 -34.922 6.309 1.00 13.57 H ATOM 866 HB3 MET A 289 11.695 -36.217 7.112 1.00 13.57 H ATOM 867 HG2 MET A 289 12.638 -36.180 4.474 1.00 16.53 H ATOM 868 HG3 MET A 289 13.412 -36.776 5.719 1.00 16.53 H ATOM 869 HE1 MET A 289 11.777 -40.018 6.381 1.00 17.98 H ATOM 870 HE2 MET A 289 13.038 -39.131 6.686 1.00 17.98 H ATOM 871 HE3 MET A 289 11.614 -38.660 7.157 1.00 17.98 H ATOM 872 N THR A 290 9.237 -33.696 6.912 1.00 11.02 N ANISOU 872 N THR A 290 1297 1386 1503 39 -224 -95 N ATOM 873 CA THR A 290 8.281 -33.107 7.883 1.00 11.36 C ANISOU 873 CA THR A 290 1216 1411 1689 72 -281 -218 C ATOM 874 C THR A 290 6.876 -33.542 7.498 1.00 11.88 C ANISOU 874 C THR A 290 1284 1417 1812 135 -258 19 C ATOM 875 O THR A 290 6.079 -33.945 8.342 1.00 12.99 O ANISOU 875 O THR A 290 1361 1587 1987 110 -132 -49 O ATOM 876 CB THR A 290 8.397 -31.579 7.842 1.00 11.78 C ANISOU 876 CB THR A 290 1359 1538 1576 105 -281 -340 C ATOM 877 OG1 THR A 290 9.694 -31.225 8.276 1.00 14.12 O ANISOU 877 OG1 THR A 290 1758 1587 2019 122 -407 -275 O ATOM 878 CG2 THR A 290 7.413 -30.895 8.749 1.00 15.68 C ANISOU 878 CG2 THR A 290 1972 1917 2068 54 116 -229 C ATOM 879 H THR A 290 9.643 -33.123 6.417 1.00 13.23 H ATOM 880 HA THR A 290 8.479 -33.422 8.790 1.00 13.64 H ATOM 881 HB THR A 290 8.258 -31.263 6.935 1.00 14.15 H ATOM 882 HG1 THR A 290 10.256 -31.561 7.782 1.00 16.96 H ATOM 883 HG21 THR A 290 7.521 -29.942 8.691 1.00 18.83 H ATOM 884 HG22 THR A 290 6.517 -31.123 8.492 1.00 18.83 H ATOM 885 HG23 THR A 290 7.558 -31.171 9.657 1.00 18.83 H ATOM 886 N LYS A 291 6.561 -33.495 6.197 1.00 12.52 N ANISOU 886 N LYS A 291 1009 1665 2085 -14 -476 105 N ATOM 887 CA LYS A 291 5.239 -33.931 5.754 1.00 14.26 C ANISOU 887 CA LYS A 291 1240 2069 2111 -66 -377 270 C ATOM 888 C LYS A 291 5.018 -35.423 6.034 1.00 13.82 C ANISOU 888 C LYS A 291 1262 1813 2177 -52 -413 -39 C ATOM 889 O LYS A 291 3.908 -35.827 6.430 1.00 15.54 O ANISOU 889 O LYS A 291 1232 2125 2549 -124 -413 200 O ATOM 890 CB LYS A 291 5.089 -33.637 4.273 1.00 17.32 C ANISOU 890 CB LYS A 291 1653 2325 2605 -197 -855 153 C ATOM 891 CG LYS A 291 4.941 -32.135 3.978 1.00 24.31 C ANISOU 891 CG LYS A 291 2983 3021 3231 30 -702 121 C ATOM 892 CD LYS A 291 4.860 -31.870 2.486 1.00 29.87 C ANISOU 892 CD LYS A 291 3884 3831 3634 23 -374 295 C ATOM 893 CE LYS A 291 4.928 -30.386 2.223 1.00 34.23 C ANISOU 893 CE LYS A 291 4373 4351 4281 308 -109 236 C ATOM 894 NZ LYS A 291 5.036 -30.184 0.770 1.00 39.76 N ANISOU 894 NZ LYS A 291 5075 4997 5035 65 209 103 N ATOM 895 H LYS A 291 7.081 -33.221 5.569 1.00 15.04 H ATOM 896 HA LYS A 291 4.554 -33.425 6.238 1.00 17.13 H ATOM 897 HB2 LYS A 291 5.876 -33.958 3.805 1.00 20.80 H ATOM 898 HB3 LYS A 291 4.297 -34.087 3.940 1.00 20.80 H ATOM 899 HG2 LYS A 291 4.126 -31.806 4.390 1.00 29.18 H ATOM 900 HG3 LYS A 291 5.711 -31.661 4.330 1.00 29.18 H ATOM 901 HD2 LYS A 291 5.608 -32.298 2.039 1.00 35.86 H ATOM 902 HD3 LYS A 291 4.019 -32.207 2.140 1.00 35.86 H ATOM 903 HE2 LYS A 291 4.118 -29.957 2.541 1.00 41.09 H ATOM 904 HE3 LYS A 291 5.711 -30.009 2.652 1.00 41.09 H ATOM 905 HZ1 LYS A 291 5.081 -29.246 0.572 1.00 47.73 H ATOM 906 HZ2 LYS A 291 5.829 -30.612 0.438 1.00 47.73 H ATOM 907 HZ3 LYS A 291 4.271 -30.560 0.329 1.00 47.73 H ATOM 908 N ASER A 292 6.055 -36.211 5.792 0.53 13.19 N ANISOU 908 N ASER A 292 1429 1832 1752 -184 -437 21 N ATOM 909 N BSER A 292 6.056 -36.232 5.828 0.20 13.05 N ANISOU 909 N BSER A 292 1471 1772 1715 -121 -234 7 N ATOM 910 N CSER A 292 6.026 -36.263 5.844 0.27 13.48 N ANISOU 910 N CSER A 292 1511 1808 1801 -161 -278 84 N ATOM 911 CA ASER A 292 5.972 -37.642 6.038 0.53 13.41 C ANISOU 911 CA ASER A 292 1557 1632 1908 -243 -81 -154 C ATOM 912 CA BSER A 292 5.982 -37.679 6.066 0.20 13.47 C ANISOU 912 CA BSER A 292 1660 1718 1741 -71 -76 -33 C ATOM 913 CA CSER A 292 5.807 -37.695 6.068 0.27 14.76 C ANISOU 913 CA CSER A 292 1841 1751 2018 3 -41 -16 C ATOM 914 C ASER A 292 5.612 -37.893 7.512 0.53 11.60 C ANISOU 914 C ASER A 292 957 1641 1810 -160 -397 100 C ATOM 915 C BSER A 292 5.680 -37.994 7.535 0.20 12.44 C ANISOU 915 C BSER A 292 1369 1635 1724 76 -87 -8 C ATOM 916 C CSER A 292 5.676 -38.032 7.568 0.27 13.15 C ANISOU 916 C CSER A 292 1454 1712 1829 193 -94 -44 C ATOM 917 O ASER A 292 4.696 -38.654 7.803 0.53 11.83 O ANISOU 917 O ASER A 292 1018 1282 2195 -108 -6 74 O ATOM 918 O BSER A 292 4.906 -38.891 7.850 0.20 13.05 O ANISOU 918 O BSER A 292 1446 1702 1809 280 -20 -31 O ATOM 919 O CSER A 292 4.987 -38.972 7.943 0.27 14.14 O ANISOU 919 O CSER A 292 1571 1845 1958 526 9 -288 O ATOM 920 CB ASER A 292 7.258 -38.359 5.592 0.53 14.21 C ANISOU 920 CB ASER A 292 2029 1689 1681 -429 -137 -350 C ATOM 921 CB BSER A 292 7.292 -38.362 5.642 0.20 15.15 C ANISOU 921 CB BSER A 292 2002 1959 1796 -223 -61 -38 C ATOM 922 CB CSER A 292 6.882 -38.537 5.373 0.27 16.09 C ANISOU 922 CB CSER A 292 2188 1978 1950 58 126 25 C ATOM 923 OG ASER A 292 7.107 -39.752 5.728 0.53 14.16 O ANISOU 923 OG ASER A 292 2146 1365 1867 -222 284 -454 O ATOM 924 OG BSER A 292 7.421 -38.425 4.235 0.20 16.21 O ANISOU 924 OG BSER A 292 2178 2067 1914 -301 68 32 O ATOM 925 OG CSER A 292 8.159 -38.298 5.921 0.27 19.54 O ANISOU 925 OG CSER A 292 2390 2235 2798 293 -153 -1 O ATOM 926 H ASER A 292 6.814 -35.944 5.487 0.53 15.84 H ATOM 927 H BSER A 292 6.825 -35.967 5.548 0.19 15.68 H ATOM 928 H CSER A 292 6.820 -36.046 5.595 0.28 16.19 H ATOM 929 HA ASER A 292 5.238 -38.002 5.496 0.53 16.11 H ATOM 930 HA BSER A 292 5.258 -38.053 5.522 0.19 16.18 H ATOM 931 HA CSER A 292 4.952 -37.933 5.653 0.28 17.73 H ATOM 932 HB2ASER A 292 7.435 -38.148 4.662 0.53 17.07 H ATOM 933 HB2BSER A 292 8.038 -37.858 6.002 0.19 18.20 H ATOM 934 HB2CSER A 292 6.664 -39.476 5.482 0.28 19.33 H ATOM 935 HB3ASER A 292 7.996 -38.064 6.148 0.53 17.07 H ATOM 936 HB3BSER A 292 7.302 -39.265 5.998 0.19 18.20 H ATOM 937 HB3CSER A 292 6.897 -38.309 4.430 0.28 19.33 H ATOM 938 HG ASER A 292 6.360 -39.925 6.020 0.53 17.00 H ATOM 939 HG BSER A 292 6.767 -38.082 3.878 0.19 19.47 H ATOM 940 HG CSER A 292 8.107 -37.745 6.523 0.28 23.46 H ATOM 941 N HIS A 293 6.322 -37.258 8.425 1.00 12.53 N ANISOU 941 N HIS A 293 1325 1588 1846 15 -216 -106 N ATOM 942 CA HIS A 293 6.117 -37.382 9.854 1.00 12.57 C ANISOU 942 CA HIS A 293 1337 1634 1804 56 14 -11 C ATOM 943 C HIS A 293 4.684 -36.985 10.210 1.00 12.34 C ANISOU 943 C HIS A 293 1276 1480 1933 22 22 -271 C ATOM 944 O HIS A 293 4.029 -37.653 11.027 1.00 13.74 O ANISOU 944 O HIS A 293 1275 1683 2262 -79 21 -203 O ATOM 945 CB HIS A 293 7.173 -36.498 10.558 1.00 12.92 C ANISOU 945 CB HIS A 293 1418 1723 1766 -47 -230 -57 C ATOM 946 CG HIS A 293 7.146 -36.515 12.046 1.00 13.15 C ANISOU 946 CG HIS A 293 1300 1484 2213 -76 8 9 C ATOM 947 ND1 HIS A 293 7.790 -35.521 12.775 1.00 14.01 N ANISOU 947 ND1 HIS A 293 1419 1733 2170 -180 -205 -17 N ATOM 948 CD2 HIS A 293 6.648 -37.397 12.957 1.00 14.67 C ANISOU 948 CD2 HIS A 293 1548 1709 2316 -330 -205 -177 C ATOM 949 CE1 HIS A 293 7.638 -35.767 14.066 1.00 14.54 C ANISOU 949 CE1 HIS A 293 1558 2194 1774 -210 -220 -90 C ATOM 950 NE2 HIS A 293 6.920 -36.886 14.207 1.00 14.67 N ANISOU 950 NE2 HIS A 293 1385 1956 2233 -190 33 63 N ATOM 951 H AHIS A 293 6.963 -36.720 8.228 0.53 15.05 H ATOM 952 H BHIS A 293 6.902 -36.658 8.216 0.20 15.05 H ATOM 953 H CHIS A 293 6.887 -36.649 8.201 0.27 15.05 H ATOM 954 HA HIS A 293 6.259 -38.312 10.126 1.00 15.10 H ATOM 955 HB2 HIS A 293 8.054 -36.795 10.281 1.00 15.51 H ATOM 956 HB3 HIS A 293 7.039 -35.579 10.277 1.00 15.51 H ATOM 957 HD2 HIS A 293 6.151 -38.160 12.770 1.00 17.61 H ATOM 958 HE1 HIS A 293 7.959 -35.238 14.759 1.00 17.47 H ATOM 959 N GLN A 294 4.191 -35.882 9.662 1.00 13.60 N ANISOU 959 N GLN A 294 1297 1527 2341 147 144 -142 N ATOM 960 CA GLN A 294 2.795 -35.510 9.900 1.00 16.63 C ANISOU 960 CA GLN A 294 1651 1966 2702 247 -42 -355 C ATOM 961 C GLN A 294 1.845 -36.602 9.447 1.00 16.09 C ANISOU 961 C GLN A 294 1198 1923 2994 271 -184 -436 C ATOM 962 O GLN A 294 0.878 -36.940 10.151 1.00 18.26 O ANISOU 962 O GLN A 294 1141 2284 3511 274 -1 -110 O ATOM 963 CB GLN A 294 2.487 -34.201 9.147 1.00 19.14 C ANISOU 963 CB GLN A 294 1611 2302 3360 379 -210 -77 C ATOM 964 CG GLN A 294 3.276 -33.029 9.708 1.00 26.27 C ANISOU 964 CG GLN A 294 3023 3038 3922 206 -7 49 C ATOM 965 CD GLN A 294 3.367 -31.711 8.882 1.00 31.18 C ANISOU 965 CD GLN A 294 3803 3873 4172 752 -123 -277 C ATOM 966 OE1 GLN A 294 3.208 -31.653 7.648 1.00 31.87 O ANISOU 966 OE1 GLN A 294 3831 3988 4289 1578 -47 262 O ATOM 967 NE2 GLN A 294 3.729 -30.638 9.623 1.00 35.43 N ANISOU 967 NE2 GLN A 294 4099 3908 5455 89 294 -451 N ATOM 968 H GLN A 294 4.629 -35.339 9.159 1.00 16.33 H ATOM 969 HA GLN A 294 2.657 -35.357 10.858 1.00 19.97 H ATOM 970 HB2 GLN A 294 2.724 -34.307 8.213 1.00 22.99 H ATOM 971 HB3 GLN A 294 1.542 -33.998 9.232 1.00 22.99 H ATOM 972 HG2 GLN A 294 2.885 -32.794 10.564 1.00 31.54 H ATOM 973 HG3 GLN A 294 4.187 -33.330 9.852 1.00 31.54 H ATOM 974 HE21 GLN A 294 3.806 -29.866 9.252 1.00 42.53 H ATOM 975 HE22 GLN A 294 3.883 -30.729 10.464 1.00 42.53 H ATOM 976 N ASN A 295 2.090 -37.167 8.271 1.00 15.83 N ANISOU 976 N ASN A 295 1316 1848 2850 121 -660 -156 N ATOM 977 CA ASN A 295 1.246 -38.266 7.786 1.00 16.84 C ANISOU 977 CA ASN A 295 1249 2334 2815 110 -661 11 C ATOM 978 C ASN A 295 1.311 -39.499 8.648 1.00 15.72 C ANISOU 978 C ASN A 295 966 2339 2666 66 -492 -131 C ATOM 979 O ASN A 295 0.298 -40.153 8.860 1.00 16.23 O ANISOU 979 O ASN A 295 1126 2214 2826 -71 -303 9 O ATOM 980 CB ASN A 295 1.658 -38.645 6.365 1.00 20.25 C ANISOU 980 CB ASN A 295 2444 2704 2546 -115 -897 109 C ATOM 981 CG ASN A 295 1.233 -37.614 5.356 1.00 28.90 C ANISOU 981 CG ASN A 295 3397 3832 3751 42 -375 30 C ATOM 982 OD1 ASN A 295 0.345 -36.821 5.643 1.00 33.46 O ANISOU 982 OD1 ASN A 295 4078 4415 4220 591 -706 723 O ATOM 983 ND2 ASN A 295 1.888 -37.587 4.186 1.00 28.88 N ANISOU 983 ND2 ASN A 295 3766 3958 3248 -341 -813 218 N ATOM 984 H ASN A 295 2.726 -36.941 7.738 1.00 19.01 H ATOM 985 HA ASN A 295 0.314 -37.963 7.761 1.00 20.22 H ATOM 986 HB2 ASN A 295 2.624 -38.725 6.326 1.00 24.31 H ATOM 987 HB3 ASN A 295 1.243 -39.489 6.128 1.00 24.31 H ATOM 988 HD21 ASN A 295 1.641 -36.930 3.501 1.00 34.67 H ATOM 989 HD22 ASN A 295 2.613 -38.224 4.015 1.00 34.67 H ATOM 990 N LEU A 296 2.481 -39.811 9.129 1.00 13.27 N ANISOU 990 N LEU A 296 1230 1780 2031 -169 -250 -13 N ATOM 991 CA LEU A 296 2.669 -40.916 10.050 1.00 12.81 C ANISOU 991 CA LEU A 296 1020 1598 2247 -158 -57 -36 C ATOM 992 C LEU A 296 1.857 -40.740 11.317 1.00 13.77 C ANISOU 992 C LEU A 296 1263 1655 2316 -195 13 54 C ATOM 993 O LEU A 296 1.181 -41.640 11.765 1.00 15.03 O ANISOU 993 O LEU A 296 1157 1935 2617 -100 0 -142 O ATOM 994 CB LEU A 296 4.153 -41.006 10.396 1.00 12.41 C ANISOU 994 CB LEU A 296 1285 1603 1826 -38 -91 -122 C ATOM 995 CG LEU A 296 4.516 -42.021 11.473 1.00 12.99 C ANISOU 995 CG LEU A 296 1407 1676 1854 30 -274 -157 C ATOM 996 CD1 LEU A 296 4.107 -43.465 11.125 1.00 14.41 C ANISOU 996 CD1 LEU A 296 1474 1768 2234 125 -76 -55 C ATOM 997 CD2 LEU A 296 6.022 -41.983 11.720 1.00 14.91 C ANISOU 997 CD2 LEU A 296 1821 1899 1943 5 -433 -71 C ATOM 998 H LEU A 296 3.208 -39.391 8.938 1.00 15.94 H ATOM 999 HA LEU A 296 2.398 -41.753 9.619 1.00 15.38 H ATOM 1000 HB2 LEU A 296 4.641 -41.247 9.593 1.00 14.91 H ATOM 1001 HB3 LEU A 296 4.449 -40.135 10.706 1.00 14.91 H ATOM 1002 HG LEU A 296 4.071 -41.775 12.299 1.00 15.61 H ATOM 1003 HD11 LEU A 296 4.366 -44.045 11.844 1.00 17.31 H ATOM 1004 HD12 LEU A 296 3.155 -43.499 11.003 1.00 17.31 H ATOM 1005 HD13 LEU A 296 4.551 -43.729 10.315 1.00 17.31 H ATOM 1006 HD21 LEU A 296 6.243 -42.625 12.399 1.00 17.90 H ATOM 1007 HD22 LEU A 296 6.478 -42.200 10.904 1.00 17.90 H ATOM 1008 HD23 LEU A 296 6.269 -41.102 12.010 1.00 17.90 H ATOM 1009 N CYS A 297 1.847 -39.527 11.871 1.00 14.67 N ANISOU 1009 N CYS A 297 1521 1783 2272 5 162 -218 N ATOM 1010 CA CYS A 297 1.109 -39.276 13.105 1.00 16.54 C ANISOU 1010 CA CYS A 297 1621 2348 2315 285 135 -618 C ATOM 1011 C CYS A 297 -0.400 -39.312 12.860 1.00 19.60 C ANISOU 1011 C CYS A 297 1669 2662 3116 545 628 -86 C ATOM 1012 O CYS A 297 -1.185 -39.734 13.725 1.00 23.09 O ANISOU 1012 O CYS A 297 1847 3427 3499 116 867 -161 O ATOM 1013 CB CYS A 297 1.522 -37.918 13.653 1.00 19.73 C ANISOU 1013 CB CYS A 297 2301 2724 2472 -125 529 -566 C ATOM 1014 SG CYS A 297 3.217 -37.905 14.373 1.00 20.75 S ANISOU 1014 SG CYS A 297 2385 2986 2512 -247 355 -477 S ATOM 1015 H CYS A 297 2.257 -38.840 11.555 1.00 17.62 H ATOM 1016 HA CYS A 297 1.335 -39.962 13.767 1.00 19.86 H ATOM 1017 HB2 CYS A 297 1.499 -37.269 12.933 1.00 23.69 H ATOM 1018 HB3 CYS A 297 0.900 -37.660 14.351 1.00 23.69 H ATOM 1019 HG CYS A 297 3.488 -36.674 14.827 1.00 24.91 H ATOM 1020 N THR A 298 -0.833 -38.945 11.658 1.00 18.97 N ANISOU 1020 N THR A 298 1314 2341 3553 311 207 -471 N ATOM 1021 CA THR A 298 -2.255 -38.929 11.315 1.00 22.72 C ANISOU 1021 CA THR A 298 1460 3139 4035 406 301 -352 C ATOM 1022 C THR A 298 -2.743 -40.337 11.006 1.00 20.88 C ANISOU 1022 C THR A 298 980 3176 3778 -18 -9 -535 C ATOM 1023 O THR A 298 -3.811 -40.753 11.413 1.00 26.09 O ANISOU 1023 O THR A 298 1229 3793 4890 -60 517 -788 O ATOM 1024 CB THR A 298 -2.469 -38.061 10.081 1.00 24.96 C ANISOU 1024 CB THR A 298 2127 3107 4249 673 -744 -83 C ATOM 1025 OG1 THR A 298 -2.095 -36.703 10.387 1.00 29.30 O ANISOU 1025 OG1 THR A 298 2757 3497 4878 586 -521 -124 O ATOM 1026 CG2 THR A 298 -3.896 -38.108 9.695 1.00 30.50 C ANISOU 1026 CG2 THR A 298 3330 3751 4509 568 -661 -180 C ATOM 1027 H THR A 298 -0.318 -38.698 11.015 1.00 22.78 H ATOM 1028 HA THR A 298 -2.777 -38.564 12.060 1.00 27.28 H ATOM 1029 HB THR A 298 -1.933 -38.394 9.345 1.00 29.97 H ATOM 1030 HG1 THR A 298 -1.306 -36.672 10.608 1.00 35.17 H ATOM 1031 HG21 THR A 298 -4.043 -37.564 8.917 1.00 36.62 H ATOM 1032 HG22 THR A 298 -4.152 -39.011 9.496 1.00 36.62 H ATOM 1033 HG23 THR A 298 -4.441 -37.780 10.413 1.00 36.62 H ATOM 1034 N LYS A 299 -1.968 -41.110 10.285 1.00 19.35 N ANISOU 1034 N LYS A 299 1330 2923 3101 194 -147 -403 N ATOM 1035 CA LYS A 299 -2.402 -42.351 9.734 1.00 18.99 C ANISOU 1035 CA LYS A 299 946 2912 3357 87 -292 -684 C ATOM 1036 C LYS A 299 -1.977 -43.563 10.595 1.00 19.44 C ANISOU 1036 C LYS A 299 752 2582 4050 -65 -22 -896 C ATOM 1037 O LYS A 299 -2.621 -44.624 10.603 1.00 21.58 O ANISOU 1037 O LYS A 299 1132 2899 4167 -579 -584 -377 O ATOM 1038 CB LYS A 299 -1.908 -42.518 8.294 1.00 22.64 C ANISOU 1038 CB LYS A 299 2168 3086 3346 -666 -488 -571 C ATOM 1039 CG LYS A 299 -2.449 -41.523 7.307 1.00 31.08 C ANISOU 1039 CG LYS A 299 3572 4086 4153 -473 -418 13 C ATOM 1040 CD LYS A 299 -1.809 -41.693 5.953 1.00 40.89 C ANISOU 1040 CD LYS A 299 5084 5273 5178 -60 -236 30 C ATOM 1041 CE LYS A 299 -2.249 -40.582 4.996 1.00 49.95 C ANISOU 1041 CE LYS A 299 6226 6321 6433 -80 -10 32 C ATOM 1042 NZ LYS A 299 -3.678 -40.733 4.609 1.00 55.32 N ANISOU 1042 NZ LYS A 299 6970 6994 7053 -66 -62 89 N ATOM 1043 H LYS A 299 -1.151 -40.921 10.096 1.00 23.24 H ATOM 1044 HA LYS A 299 -3.382 -42.346 9.705 1.00 22.80 H ATOM 1045 HB2 LYS A 299 -0.942 -42.436 8.290 1.00 27.18 H ATOM 1046 HB3 LYS A 299 -2.160 -43.402 7.984 1.00 27.18 H ATOM 1047 HG2 LYS A 299 -3.406 -41.653 7.211 1.00 37.32 H ATOM 1048 HG3 LYS A 299 -2.262 -40.624 7.622 1.00 37.32 H ATOM 1049 HD2 LYS A 299 -0.844 -41.653 6.045 1.00 49.08 H ATOM 1050 HD3 LYS A 299 -2.077 -42.546 5.575 1.00 49.08 H ATOM 1051 HE2 LYS A 299 -2.141 -39.722 5.432 1.00 59.96 H ATOM 1052 HE3 LYS A 299 -1.710 -40.620 4.191 1.00 59.96 H ATOM 1053 HZ1 LYS A 299 -3.932 -40.027 4.010 1.00 66.39 H ATOM 1054 HZ2 LYS A 299 -3.812 -41.577 4.170 1.00 66.39 H ATOM 1055 HZ3 LYS A 299 -4.235 -40.695 5.390 1.00 66.39 H ATOM 1056 N GLY A 300 -0.867 -43.442 11.289 1.00 16.67 N ANISOU 1056 N GLY A 300 725 2456 3155 110 -87 -659 N ATOM 1057 CA GLY A 300 -0.329 -44.524 12.100 1.00 15.29 C ANISOU 1057 CA GLY A 300 837 2270 2702 -50 94 -770 C ATOM 1058 C GLY A 300 0.804 -45.333 11.494 1.00 14.72 C ANISOU 1058 C GLY A 300 821 2182 2589 -254 -126 -381 C ATOM 1059 O GLY A 300 1.535 -45.968 12.214 1.00 13.95 O ANISOU 1059 O GLY A 300 883 2025 2393 -147 -126 -317 O ATOM 1060 H GLY A 300 -0.391 -42.726 11.311 1.00 20.02 H ATOM 1061 HA2 GLY A 300 -0.007 -44.151 12.936 1.00 18.36 H ATOM 1062 HA3 GLY A 300 -1.049 -45.139 12.310 1.00 18.36 H ATOM 1063 N AGLN A 301 0.953 -45.285 10.170 0.51 15.13 N ANISOU 1063 N AGLN A 301 985 2260 2502 62 -118 -484 N ATOM 1064 N BGLN A 301 0.914 -45.304 10.173 0.49 14.84 N ANISOU 1064 N BGLN A 301 785 2372 2480 117 -66 -410 N ATOM 1065 CA AGLN A 301 1.985 -46.047 9.470 0.51 15.63 C ANISOU 1065 CA AGLN A 301 1297 2451 2188 -141 -680 -379 C ATOM 1066 CA BGLN A 301 2.043 -45.871 9.477 0.49 15.05 C ANISOU 1066 CA BGLN A 301 1045 2396 2278 158 -334 -144 C ATOM 1067 C AGLN A 301 2.240 -45.417 8.106 0.51 15.56 C ANISOU 1067 C AGLN A 301 1179 2627 2108 -120 -503 -379 C ATOM 1068 C BGLN A 301 2.322 -45.007 8.291 0.49 13.98 C ANISOU 1068 C BGLN A 301 1048 2326 1939 463 -377 -11 C ATOM 1069 O AGLN A 301 1.274 -45.179 7.349 0.51 17.27 O ANISOU 1069 O AGLN A 301 1395 2783 2385 269 -116 49 O ATOM 1070 O BGLN A 301 1.483 -44.274 7.800 0.49 17.03 O ANISOU 1070 O BGLN A 301 1695 2659 2116 859 -368 3 O ATOM 1071 CB AGLN A 301 1.594 -47.515 9.345 0.51 16.32 C ANISOU 1071 CB AGLN A 301 1789 2365 2048 -169 -359 31 C ATOM 1072 CB BGLN A 301 1.764 -47.306 9.011 0.49 14.76 C ANISOU 1072 CB BGLN A 301 1355 2105 2149 56 -185 -718 C ATOM 1073 CG AGLN A 301 2.737 -48.346 8.882 0.51 15.85 C ANISOU 1073 CG AGLN A 301 2014 2065 1942 72 -227 -446 C ATOM 1074 CG BGLN A 301 1.749 -48.301 10.160 0.49 15.64 C ANISOU 1074 CG BGLN A 301 1749 1693 2502 -236 -548 -463 C ATOM 1075 CD AGLN A 301 2.367 -49.816 8.708 0.51 18.31 C ANISOU 1075 CD AGLN A 301 2428 2454 2077 -144 -327 -739 C ATOM 1076 CD BGLN A 301 1.641 -49.757 9.731 0.49 19.09 C ANISOU 1076 CD BGLN A 301 2066 2245 2942 -300 -248 -324 C ATOM 1077 OE1AGLN A 301 1.456 -50.182 7.952 0.51 21.47 O ANISOU 1077 OE1AGLN A 301 2746 2894 2518 -358 -443 -524 O ATOM 1078 OE1BGLN A 301 0.688 -50.142 9.111 0.49 19.74 O ANISOU 1078 OE1BGLN A 301 2272 2312 2914 -316 -207 -956 O ATOM 1079 NE2AGLN A 301 3.124 -50.680 9.364 0.51 18.97 N ANISOU 1079 NE2AGLN A 301 2702 2139 2368 -287 -231 -185 N ATOM 1080 NE2BGLN A 301 2.599 -50.568 10.131 0.49 16.18 N ANISOU 1080 NE2BGLN A 301 1817 1790 2539 -28 -772 -571 N ATOM 1081 H AGLN A 301 0.461 -44.811 9.648 0.51 18.17 H ATOM 1082 H BGLN A 301 0.330 -44.951 9.651 0.49 17.82 H ATOM 1083 HA AGLN A 301 2.818 -46.000 9.984 0.51 18.76 H ATOM 1084 HA BGLN A 301 2.830 -45.873 10.061 0.49 18.08 H ATOM 1085 HB2AGLN A 301 1.309 -47.845 10.211 0.51 19.60 H ATOM 1086 HB2BGLN A 301 0.897 -47.335 8.577 0.49 17.73 H ATOM 1087 HB3AGLN A 301 0.875 -47.600 8.699 0.51 19.60 H ATOM 1088 HB3BGLN A 301 2.457 -47.577 8.388 0.49 17.73 H ATOM 1089 HG2AGLN A 301 3.044 -48.011 8.025 0.51 19.03 H ATOM 1090 HG2BGLN A 301 2.570 -48.204 10.667 0.49 18.79 H ATOM 1091 HG3AGLN A 301 3.451 -48.292 9.535 0.51 19.03 H ATOM 1092 HG3BGLN A 301 0.988 -48.106 10.730 0.49 18.79 H ATOM 1093 HE21AGLN A 301 2.964 -51.523 9.305 0.51 22.78 H ATOM 1094 HE21BGLN A 301 2.578 -51.400 9.911 0.49 19.43 H ATOM 1095 HE22AGLN A 301 3.775 -50.399 9.849 0.51 22.78 H ATOM 1096 HE22BGLN A 301 3.246 -50.267 10.611 0.49 19.43 H ATOM 1097 N VAL A 302 3.524 -45.172 7.790 1.00 14.05 N ANISOU 1097 N VAL A 302 1216 2147 1974 142 -301 -17 N ATOM 1098 CA VAL A 302 3.921 -44.572 6.514 1.00 16.76 C ANISOU 1098 CA VAL A 302 1836 2494 2039 657 -61 -5 C ATOM 1099 C VAL A 302 5.192 -45.165 6.011 1.00 13.62 C ANISOU 1099 C VAL A 302 1141 2508 1528 -124 -86 -440 C ATOM 1100 O VAL A 302 6.011 -45.638 6.752 1.00 14.96 O ANISOU 1100 O VAL A 302 1218 2898 1569 226 -334 -71 O ATOM 1101 CB VAL A 302 4.163 -43.012 6.706 1.00 24.97 C ANISOU 1101 CB VAL A 302 3248 3192 3047 1260 614 654 C ATOM 1102 CG1 VAL A 302 5.519 -42.720 7.272 1.00 34.45 C ANISOU 1102 CG1 VAL A 302 4660 4146 4282 67 878 -218 C ATOM 1103 CG2 VAL A 302 3.953 -42.282 5.416 1.00 41.80 C ANISOU 1103 CG2 VAL A 302 5251 5099 5531 606 335 -133 C ATOM 1104 H AVAL A 302 4.187 -45.349 8.308 0.51 16.87 H ATOM 1105 H BVAL A 302 4.145 -45.632 8.167 0.49 16.87 H ATOM 1106 HA VAL A 302 3.218 -44.708 5.845 1.00 20.13 H ATOM 1107 HB VAL A 302 3.501 -42.673 7.345 1.00 29.98 H ATOM 1108 HG11 VAL A 302 5.618 -41.770 7.370 1.00 41.35 H ATOM 1109 HG12 VAL A 302 5.598 -43.148 8.128 1.00 41.35 H ATOM 1110 HG13 VAL A 302 6.187 -43.060 6.673 1.00 41.35 H ATOM 1111 HG21 VAL A 302 4.105 -41.345 5.559 1.00 50.17 H ATOM 1112 HG22 VAL A 302 4.572 -42.618 4.763 1.00 50.17 H ATOM 1113 HG23 VAL A 302 3.052 -42.427 5.118 1.00 50.17 H ATOM 1114 N AVAL A 303 5.379 -45.159 4.702 0.67 13.23 N ANISOU 1114 N AVAL A 303 1096 2386 1546 231 -319 -211 N ATOM 1115 N BVAL A 303 5.428 -44.990 4.718 0.33 15.45 N ANISOU 1115 N BVAL A 303 1654 2364 1851 -169 -87 -207 N ATOM 1116 CA AVAL A 303 6.686 -45.338 4.078 0.67 11.82 C ANISOU 1116 CA AVAL A 303 1256 1841 1394 -67 -130 -301 C ATOM 1117 CA BVAL A 303 6.763 -45.088 4.130 0.33 15.97 C ANISOU 1117 CA BVAL A 303 1867 2092 2109 -43 -91 -159 C ATOM 1118 C AVAL A 303 7.179 -44.003 3.585 0.67 11.66 C ANISOU 1118 C AVAL A 303 1339 1990 1100 238 -409 -124 C ATOM 1119 C BVAL A 303 7.204 -43.672 3.789 0.33 15.29 C ANISOU 1119 C BVAL A 303 1818 2014 1979 99 -81 -521 C ATOM 1120 O AVAL A 303 6.478 -43.344 2.838 0.67 13.08 O ANISOU 1120 O AVAL A 303 1298 2250 1423 144 -492 -77 O ATOM 1121 O BVAL A 303 6.388 -42.831 3.372 0.33 17.12 O ANISOU 1121 O BVAL A 303 1933 2307 2265 103 -318 -447 O ATOM 1122 CB AVAL A 303 6.644 -46.393 2.963 0.67 16.47 C ANISOU 1122 CB AVAL A 303 1990 2162 2106 -327 352 -720 C ATOM 1123 CB BVAL A 303 6.819 -45.980 2.868 0.33 20.30 C ANISOU 1123 CB BVAL A 303 2463 2552 2698 136 123 -151 C ATOM 1124 CG1AVAL A 303 8.078 -46.607 2.429 0.67 16.74 C ANISOU 1124 CG1AVAL A 303 1969 2151 2241 -284 201 -554 C ATOM 1125 CG1BVAL A 303 6.709 -47.451 3.243 0.33 20.19 C ANISOU 1125 CG1BVAL A 303 2540 2616 2514 107 166 -547 C ATOM 1126 CG2AVAL A 303 6.054 -47.694 3.498 0.67 20.38 C ANISOU 1126 CG2AVAL A 303 2485 2532 2728 -889 169 -1012 C ATOM 1127 CG2BVAL A 303 5.741 -45.609 1.891 0.33 21.66 C ANISOU 1127 CG2BVAL A 303 2830 2771 2628 -228 -131 -317 C ATOM 1128 H AVAL A 303 4.744 -45.050 4.132 0.67 15.89 H ATOM 1129 H BVAL A 303 4.815 -44.808 4.142 0.33 18.55 H ATOM 1130 HA AVAL A 303 7.316 -45.653 4.759 0.67 14.20 H ATOM 1131 HA BVAL A 303 7.384 -45.454 4.794 0.33 19.18 H ATOM 1132 HB AVAL A 303 6.080 -46.072 2.228 0.67 19.78 H ATOM 1133 HB BVAL A 303 7.683 -45.847 2.425 0.33 24.37 H ATOM 1134 HG11AVAL A 303 8.056 -47.267 1.731 0.67 20.11 H ATOM 1135 HG11BVAL A 303 6.747 -47.981 2.443 0.33 24.24 H ATOM 1136 HG12AVAL A 303 8.411 -45.776 2.083 0.67 20.11 H ATOM 1137 HG12BVAL A 303 7.439 -47.681 3.823 0.33 24.24 H ATOM 1138 HG13AVAL A 303 8.637 -46.910 3.148 0.67 20.11 H ATOM 1139 HG13BVAL A 303 5.875 -47.597 3.694 0.33 24.24 H ATOM 1140 HG21AVAL A 303 6.034 -48.342 2.790 0.67 24.47 H ATOM 1141 HG21BVAL A 303 5.806 -46.181 1.122 0.33 26.00 H ATOM 1142 HG22AVAL A 303 6.602 -48.012 4.219 0.67 24.47 H ATOM 1143 HG22BVAL A 303 4.886 -45.722 2.312 0.33 26.00 H ATOM 1144 HG23AVAL A 303 5.163 -47.526 3.814 0.67 24.47 H ATOM 1145 HG23BVAL A 303 5.859 -44.693 1.628 0.33 26.00 H ATOM 1146 N ASER A 304 8.355 -43.588 4.024 0.67 11.56 N ANISOU 1146 N ASER A 304 1224 1785 1384 178 -224 -260 N ATOM 1147 N BSER A 304 8.485 -43.396 3.977 0.33 14.52 N ANISOU 1147 N BSER A 304 1782 1894 1840 270 -241 -387 N ATOM 1148 CA ASER A 304 8.924 -42.328 3.517 0.67 12.57 C ANISOU 1148 CA ASER A 304 1389 1784 1603 219 -522 68 C ATOM 1149 CA BSER A 304 9.004 -42.033 3.843 0.33 13.71 C ANISOU 1149 CA BSER A 304 1782 1590 1837 156 -104 -483 C ATOM 1150 C ASER A 304 9.217 -42.387 2.033 0.67 12.74 C ANISOU 1150 C ASER A 304 1501 1791 1548 170 -527 65 C ATOM 1151 C BSER A 304 9.244 -41.562 2.411 0.33 14.47 C ANISOU 1151 C BSER A 304 1910 1584 2002 -99 -515 -181 C ATOM 1152 O ASER A 304 9.313 -43.474 1.478 0.67 13.74 O ANISOU 1152 O ASER A 304 1772 1918 1530 11 -325 -169 O ATOM 1153 O BSER A 304 9.262 -40.350 2.146 0.33 13.99 O ANISOU 1153 O BSER A 304 1734 1611 1970 104 -133 246 O ATOM 1154 CB ASER A 304 10.207 -42.014 4.255 0.67 11.96 C ANISOU 1154 CB ASER A 304 1712 1326 1505 408 -137 -306 C ATOM 1155 CB BSER A 304 10.322 -41.928 4.590 0.33 13.51 C ANISOU 1155 CB BSER A 304 1723 1654 1756 -40 -30 36 C ATOM 1156 OG ASER A 304 11.263 -42.832 3.788 0.67 11.59 O ANISOU 1156 OG ASER A 304 1505 1454 1444 -204 -545 121 O ATOM 1157 OG BSER A 304 11.271 -42.831 4.030 0.33 12.95 O ANISOU 1157 OG BSER A 304 1519 1779 1620 -26 154 -309 O ATOM 1158 H ASER A 304 8.842 -43.999 4.601 0.67 13.89 H ATOM 1159 H BSER A 304 9.082 -43.979 4.184 0.33 17.44 H ATOM 1160 HA ASER A 304 8.289 -41.599 3.677 0.67 15.10 H ATOM 1161 HA BSER A 304 8.371 -41.412 4.261 0.33 16.47 H ATOM 1162 HB2ASER A 304 10.438 -41.084 4.106 0.67 14.36 H ATOM 1163 HB2BSER A 304 10.660 -41.022 4.514 0.33 16.22 H ATOM 1164 HB3ASER A 304 10.075 -42.177 5.202 0.67 14.36 H ATOM 1165 HB3BSER A 304 10.179 -42.154 5.523 0.33 16.22 H ATOM 1166 HG ASER A 304 11.954 -42.656 4.193 0.67 13.92 H ATOM 1167 HG BSER A 304 10.932 -43.243 3.406 0.33 15.55 H ATOM 1168 N AGLY A 305 9.386 -41.220 1.407 0.67 13.63 N ANISOU 1168 N AGLY A 305 1496 2089 1593 362 -522 -198 N ATOM 1169 N BGLY A 305 9.478 -42.496 1.491 0.33 12.74 N ANISOU 1169 N BGLY A 305 1960 1517 1364 -224 -478 -163 N ATOM 1170 CA AGLY A 305 10.065 -41.166 0.130 0.67 14.19 C ANISOU 1170 CA AGLY A 305 1925 1994 1474 116 -119 -184 C ATOM 1171 CA BGLY A 305 10.034 -42.159 0.186 0.33 14.53 C ANISOU 1171 CA BGLY A 305 1753 1834 1934 -178 -525 -23 C ATOM 1172 C AGLY A 305 11.528 -41.517 0.356 0.67 14.14 C ANISOU 1172 C AGLY A 305 1756 2133 1484 82 -432 -384 C ATOM 1173 C BGLY A 305 11.544 -42.026 0.333 0.33 12.55 C ANISOU 1173 C BGLY A 305 1463 1536 1769 -74 -498 -9 C ATOM 1174 O AGLY A 305 12.010 -41.671 1.477 0.67 12.87 O ANISOU 1174 O AGLY A 305 1615 1807 1467 25 -175 -103 O ATOM 1175 O BGLY A 305 12.089 -42.216 1.409 0.33 11.35 O ANISOU 1175 O BGLY A 305 1631 1260 1423 -69 -283 -109 O ATOM 1176 HA2AGLY A 305 9.673 -41.804 -0.487 0.67 17.05 H ATOM 1177 HA2BGLY A 305 9.834 -42.858 -0.456 0.33 17.45 H ATOM 1178 HA3AGLY A 305 10.003 -40.274 -0.247 0.67 17.05 H ATOM 1179 HA3BGLY A 305 9.667 -41.318 -0.130 0.33 17.45 H ATOM 1180 N GLN A 306 12.273 -41.677 -0.724 1.00 13.97 N ANISOU 1180 N GLN A 306 1790 1908 1609 -66 -227 -175 N ATOM 1181 CA GLN A 306 13.688 -41.749 -0.617 1.00 12.96 C ANISOU 1181 CA GLN A 306 1849 1657 1417 -211 12 -113 C ATOM 1182 C GLN A 306 14.211 -40.453 -0.036 1.00 12.82 C ANISOU 1182 C GLN A 306 1953 1309 1609 -377 61 -148 C ATOM 1183 O GLN A 306 13.742 -39.377 -0.410 1.00 16.01 O ANISOU 1183 O GLN A 306 2599 1324 2161 80 -500 43 O ATOM 1184 CB GLN A 306 14.310 -41.921 -2.001 1.00 14.91 C ANISOU 1184 CB GLN A 306 2211 1888 1568 -301 222 -158 C ATOM 1185 CG GLN A 306 13.830 -43.189 -2.726 1.00 17.96 C ANISOU 1185 CG GLN A 306 2700 2263 1862 -161 125 -431 C ATOM 1186 CD GLN A 306 14.416 -43.352 -4.085 1.00 21.42 C ANISOU 1186 CD GLN A 306 3462 2245 2433 -175 644 -463 C ATOM 1187 OE1 GLN A 306 14.783 -42.373 -4.759 1.00 26.31 O ANISOU 1187 OE1 GLN A 306 4205 3066 2725 -504 829 -339 O ATOM 1188 NE2 GLN A 306 14.482 -44.582 -4.527 1.00 23.22 N ANISOU 1188 NE2 GLN A 306 3643 2726 2454 -508 579 -514 N ATOM 1189 H AGLN A 306 11.970 -41.745 -1.526 0.67 16.77 H ATOM 1190 H BGLN A 306 11.969 -41.406 -1.482 0.33 16.77 H ATOM 1191 HA GLN A 306 13.952 -42.497 -0.042 1.00 15.56 H ATOM 1192 HB2 GLN A 306 14.074 -41.157 -2.550 1.00 17.91 H ATOM 1193 HB3 GLN A 306 15.274 -41.977 -1.908 1.00 17.91 H ATOM 1194 HG2 GLN A 306 14.079 -43.965 -2.200 1.00 21.57 H ATOM 1195 HG3 GLN A 306 12.865 -43.151 -2.821 1.00 21.57 H ATOM 1196 HE21 GLN A 306 14.811 -44.742 -5.305 1.00 27.88 H ATOM 1197 HE22 GLN A 306 14.197 -45.231 -4.039 1.00 27.88 H ATOM 1198 N TYR A 307 15.197 -40.531 0.861 1.00 10.80 N ANISOU 1198 N TYR A 307 1503 1243 1356 -151 74 -99 N ATOM 1199 CA TYR A 307 15.766 -39.340 1.431 1.00 10.13 C ANISOU 1199 CA TYR A 307 1320 1071 1459 -94 11 -102 C ATOM 1200 C TYR A 307 17.235 -39.624 1.716 1.00 10.55 C ANISOU 1200 C TYR A 307 1563 1173 1273 -131 215 7 C ATOM 1201 O TYR A 307 17.684 -40.769 1.742 1.00 11.38 O ANISOU 1201 O TYR A 307 1463 1073 1788 7 230 -88 O ATOM 1202 CB TYR A 307 15.045 -38.831 2.640 1.00 10.76 C ANISOU 1202 CB TYR A 307 1440 1033 1615 -58 245 -49 C ATOM 1203 CG TYR A 307 15.096 -39.739 3.855 1.00 10.60 C ANISOU 1203 CG TYR A 307 1406 1084 1536 -139 258 -295 C ATOM 1204 CD1 TYR A 307 14.277 -40.835 3.973 1.00 10.61 C ANISOU 1204 CD1 TYR A 307 1388 1351 1293 -153 176 -261 C ATOM 1205 CD2 TYR A 307 15.963 -39.468 4.911 1.00 11.14 C ANISOU 1205 CD2 TYR A 307 1672 1223 1338 -373 267 -163 C ATOM 1206 CE1 TYR A 307 14.282 -41.649 5.098 1.00 10.17 C ANISOU 1206 CE1 TYR A 307 1466 1206 1191 -201 159 -129 C ATOM 1207 CE2 TYR A 307 16.006 -40.247 6.010 1.00 11.61 C ANISOU 1207 CE2 TYR A 307 1648 1528 1237 -361 142 -293 C ATOM 1208 CZ TYR A 307 15.158 -41.329 6.118 1.00 10.64 C ANISOU 1208 CZ TYR A 307 1631 1396 1017 -395 168 -57 C ATOM 1209 OH TYR A 307 15.151 -42.012 7.273 1.00 12.66 O ANISOU 1209 OH TYR A 307 1834 1640 1337 -346 -10 -110 O ATOM 1210 H TYR A 307 15.544 -41.264 1.147 1.00 12.97 H ATOM 1211 HA TYR A 307 15.732 -38.631 0.756 1.00 12.17 H ATOM 1212 HB2 TYR A 307 15.435 -37.980 2.895 1.00 12.93 H ATOM 1213 HB3 TYR A 307 14.111 -38.704 2.410 1.00 12.93 H ATOM 1214 HD1 TYR A 307 13.680 -41.025 3.285 1.00 12.75 H ATOM 1215 HD2 TYR A 307 16.526 -38.729 4.856 1.00 13.38 H ATOM 1216 HE1 TYR A 307 13.697 -42.368 5.175 1.00 12.21 H ATOM 1217 HE2 TYR A 307 16.567 -40.023 6.718 1.00 13.95 H ATOM 1218 HH TYR A 307 15.311 -42.803 7.131 1.00 15.21 H ATOM 1219 N ARG A 308 17.968 -38.529 1.997 1.00 10.56 N ANISOU 1219 N ARG A 308 1269 1199 1543 -62 94 -276 N ATOM 1220 CA ARG A 308 19.361 -38.591 2.342 1.00 10.93 C ANISOU 1220 CA ARG A 308 1409 1119 1626 -70 299 -205 C ATOM 1221 C ARG A 308 19.582 -38.356 3.834 1.00 10.27 C ANISOU 1221 C ARG A 308 1343 1168 1389 102 217 -234 C ATOM 1222 O ARG A 308 19.091 -37.371 4.378 1.00 10.57 O ANISOU 1222 O ARG A 308 1462 1133 1420 -15 132 -154 O ATOM 1223 CB ARG A 308 20.140 -37.584 1.521 1.00 11.82 C ANISOU 1223 CB ARG A 308 1674 1328 1490 -176 191 -154 C ATOM 1224 CG ARG A 308 20.262 -37.985 0.054 1.00 14.28 C ANISOU 1224 CG ARG A 308 2062 1788 1574 -324 408 -154 C ATOM 1225 CD ARG A 308 20.452 -36.650 -0.834 1.00 17.63 C ANISOU 1225 CD ARG A 308 2598 2126 1973 419 249 -238 C ATOM 1226 NE ARG A 308 19.180 -35.920 -0.908 1.00 18.69 N ANISOU 1226 NE ARG A 308 3139 2202 1760 -828 387 -155 N ATOM 1227 CZ ARG A 308 18.917 -35.043 -1.862 1.00 19.11 C ANISOU 1227 CZ ARG A 308 2984 2069 2208 75 272 -25 C ATOM 1228 NH1 ARG A 308 19.878 -34.659 -2.693 1.00 24.16 N ANISOU 1228 NH1 ARG A 308 3845 2790 2546 550 1453 597 N ATOM 1229 NH2 ARG A 308 17.714 -34.498 -1.940 1.00 20.28 N ANISOU 1229 NH2 ARG A 308 3275 2348 2081 32 409 -236 N ATOM 1230 H ARG A 308 17.653 -37.729 1.988 1.00 12.68 H ATOM 1231 HA ARG A 308 19.701 -39.484 2.125 1.00 13.13 H ATOM 1232 HB2 ARG A 308 19.688 -36.727 1.560 1.00 14.20 H ATOM 1233 HB3 ARG A 308 21.035 -37.504 1.885 1.00 14.20 H ATOM 1234 HG2 ARG A 308 21.038 -38.555 -0.067 1.00 17.15 H ATOM 1235 HG3 ARG A 308 19.454 -38.438 -0.231 1.00 17.15 H ATOM 1236 HD2 ARG A 308 21.116 -36.075 -0.421 1.00 21.17 H ATOM 1237 HD3 ARG A 308 20.723 -36.892 -1.734 1.00 21.17 H ATOM 1238 HE ARG A 308 18.438 -36.245 -0.374 1.00 22.44 H ATOM 1239 HH11 ARG A 308 20.651 -35.034 -2.658 1.00 29.01 H ATOM 1240 HH12 ARG A 308 19.713 -34.069 -3.297 1.00 29.01 H ATOM 1241 HH21 ARG A 308 17.104 -34.719 -1.375 1.00 24.35 H ATOM 1242 HH22 ARG A 308 17.559 -33.879 -2.517 1.00 24.35 H ATOM 1243 N MET A 309 20.366 -39.244 4.464 1.00 10.06 N ANISOU 1243 N MET A 309 1089 1163 1572 -26 131 -257 N ATOM 1244 CA MET A 309 20.733 -39.154 5.862 1.00 10.13 C ANISOU 1244 CA MET A 309 1063 1134 1653 21 185 -124 C ATOM 1245 C MET A 309 22.222 -38.902 5.945 1.00 10.63 C ANISOU 1245 C MET A 309 1091 1294 1654 26 232 -4 C ATOM 1246 O MET A 309 23.041 -39.587 5.345 1.00 11.50 O ANISOU 1246 O MET A 309 1060 1389 1921 7 286 -37 O ATOM 1247 CB MET A 309 20.366 -40.450 6.596 1.00 11.67 C ANISOU 1247 CB MET A 309 1340 1235 1858 -35 65 -220 C ATOM 1248 CG MET A 309 20.642 -40.339 8.125 1.00 13.08 C ANISOU 1248 CG MET A 309 1575 1520 1874 -48 172 123 C ATOM 1249 SD MET A 309 20.204 -41.749 9.063 1.00 15.47 S ANISOU 1249 SD MET A 309 2320 1524 2034 -173 211 127 S ATOM 1250 CE MET A 309 20.698 -41.193 10.714 1.00 20.91 C ANISOU 1250 CE MET A 309 2676 2348 2920 31 34 466 C ATOM 1251 H MET A 309 20.704 -39.931 4.074 1.00 12.09 H ATOM 1252 HA MET A 309 20.250 -38.411 6.281 1.00 12.18 H ATOM 1253 HB2 MET A 309 19.422 -40.633 6.470 1.00 14.02 H ATOM 1254 HB3 MET A 309 20.899 -41.179 6.243 1.00 14.02 H ATOM 1255 HG2 MET A 309 21.591 -40.184 8.256 1.00 15.71 H ATOM 1256 HG3 MET A 309 20.139 -39.587 8.475 1.00 15.71 H ATOM 1257 HE1 MET A 309 20.509 -41.890 11.347 1.00 25.10 H ATOM 1258 HE2 MET A 309 21.639 -41.001 10.710 1.00 25.10 H ATOM 1259 HE3 MET A 309 20.203 -40.402 10.938 1.00 25.10 H ATOM 1260 N LEU A 310 22.558 -37.890 6.734 1.00 11.03 N ANISOU 1260 N LEU A 310 1114 1224 1854 -103 52 65 N ATOM 1261 CA LEU A 310 23.939 -37.491 6.969 1.00 12.76 C ANISOU 1261 CA LEU A 310 1556 1127 2163 -111 -322 144 C ATOM 1262 C LEU A 310 24.719 -38.565 7.692 1.00 12.75 C ANISOU 1262 C LEU A 310 1165 1324 2358 -180 3 108 C ATOM 1263 O LEU A 310 24.309 -39.069 8.721 1.00 13.17 O ANISOU 1263 O LEU A 310 1454 1487 2063 -128 -30 356 O ATOM 1264 CB LEU A 310 23.893 -36.265 7.843 1.00 15.70 C ANISOU 1264 CB LEU A 310 1909 1513 2542 -75 -909 66 C ATOM 1265 CG LEU A 310 25.206 -35.663 8.332 1.00 18.56 C ANISOU 1265 CG LEU A 310 2433 1858 2759 -599 -974 389 C ATOM 1266 CD1 LEU A 310 25.889 -34.963 7.209 1.00 21.17 C ANISOU 1266 CD1 LEU A 310 2406 2250 3389 -797 -593 457 C ATOM 1267 CD2 LEU A 310 25.025 -34.716 9.566 1.00 20.01 C ANISOU 1267 CD2 LEU A 310 2617 2203 2782 -429 -1114 265 C ATOM 1268 H LEU A 310 21.987 -37.405 7.156 1.00 13.25 H ATOM 1269 HA LEU A 310 24.384 -37.274 6.123 1.00 15.32 H ATOM 1270 HB2 LEU A 310 23.433 -35.568 7.350 1.00 18.85 H ATOM 1271 HB3 LEU A 310 23.375 -36.485 8.633 1.00 18.85 H ATOM 1272 HG LEU A 310 25.785 -36.389 8.612 1.00 22.28 H ATOM 1273 HD11 LEU A 310 26.713 -34.589 7.530 1.00 25.42 H ATOM 1274 HD12 LEU A 310 26.067 -35.595 6.509 1.00 25.42 H ATOM 1275 HD13 LEU A 310 25.317 -34.264 6.883 1.00 25.42 H ATOM 1276 HD21 LEU A 310 25.884 -34.372 9.823 1.00 24.03 H ATOM 1277 HD22 LEU A 310 24.442 -33.993 9.321 1.00 24.03 H ATOM 1278 HD23 LEU A 310 24.642 -35.216 10.290 1.00 24.03 H ATOM 1279 N ALA A 311 25.865 -38.916 7.124 1.00 13.21 N ANISOU 1279 N ALA A 311 1359 1427 2232 -286 -74 212 N ATOM 1280 CA ALA A 311 26.762 -39.896 7.734 1.00 15.08 C ANISOU 1280 CA ALA A 311 1124 1603 3004 -62 -306 359 C ATOM 1281 C ALA A 311 27.738 -39.238 8.691 1.00 14.10 C ANISOU 1281 C ALA A 311 1187 1412 2757 -197 -378 276 C ATOM 1282 O ALA A 311 28.051 -38.051 8.560 1.00 18.02 O ANISOU 1282 O ALA A 311 1594 1689 3562 -391 -612 237 O ATOM 1283 CB ALA A 311 27.544 -40.607 6.613 1.00 16.89 C ANISOU 1283 CB ALA A 311 1535 1809 3072 -27 190 72 C ATOM 1284 H ALA A 311 26.151 -38.599 6.377 1.00 15.86 H ATOM 1285 HA ALA A 311 26.239 -40.563 8.226 1.00 18.11 H ATOM 1286 HB1 ALA A 311 28.135 -41.252 7.007 1.00 20.28 H ATOM 1287 HB2 ALA A 311 26.921 -41.046 6.029 1.00 20.28 H ATOM 1288 HB3 ALA A 311 28.049 -39.954 6.123 1.00 20.28 H ATOM 1289 N LYS A 312 28.253 -40.033 9.616 1.00 15.63 N ANISOU 1289 N LYS A 312 1201 1623 3115 -80 -280 199 N ATOM 1290 CA LYS A 312 29.125 -39.476 10.680 1.00 16.50 C ANISOU 1290 CA LYS A 312 1282 2067 2920 -383 -657 9 C ATOM 1291 C LYS A 312 30.354 -38.785 10.132 1.00 20.06 C ANISOU 1291 C LYS A 312 1810 2421 3392 -600 -772 224 C ATOM 1292 O LYS A 312 30.718 -37.723 10.610 1.00 23.88 O ANISOU 1292 O LYS A 312 2297 2489 4285 -1108 -922 217 O ATOM 1293 CB LYS A 312 29.497 -40.574 11.689 1.00 17.91 C ANISOU 1293 CB LYS A 312 1701 2024 3082 -254 -754 538 C ATOM 1294 CG LYS A 312 30.344 -40.017 12.871 1.00 20.59 C ANISOU 1294 CG LYS A 312 1896 2622 3306 -350 -1099 766 C ATOM 1295 CD LYS A 312 30.562 -41.054 13.913 1.00 24.05 C ANISOU 1295 CD LYS A 312 2504 3168 3466 -748 -1491 637 C ATOM 1296 CE LYS A 312 31.257 -40.433 15.123 1.00 25.70 C ANISOU 1296 CE LYS A 312 2817 3588 3358 -596 -1522 746 C ATOM 1297 NZ LYS A 312 31.402 -41.510 16.123 1.00 33.41 N ANISOU 1297 NZ LYS A 312 3801 4287 4605 -107 -884 354 N ATOM 1298 H LYS A 312 28.126 -40.882 9.663 1.00 18.77 H ATOM 1299 HA LYS A 312 28.611 -38.799 11.169 1.00 19.81 H ATOM 1300 HB2 LYS A 312 28.685 -40.959 12.053 1.00 21.51 H ATOM 1301 HB3 LYS A 312 30.018 -41.257 11.238 1.00 21.51 H ATOM 1302 HG2 LYS A 312 31.209 -39.732 12.539 1.00 24.72 H ATOM 1303 HG3 LYS A 312 29.876 -39.271 13.277 1.00 24.72 H ATOM 1304 HD2 LYS A 312 29.708 -41.413 14.198 1.00 28.88 H ATOM 1305 HD3 LYS A 312 31.128 -41.757 13.558 1.00 28.88 H ATOM 1306 HE2 LYS A 312 32.137 -40.108 14.874 1.00 30.85 H ATOM 1307 HE3 LYS A 312 30.712 -39.722 15.495 1.00 30.85 H ATOM 1308 HZ1 LYS A 312 31.836 -41.171 16.910 1.00 40.10 H ATOM 1309 HZ2 LYS A 312 30.537 -41.850 16.366 1.00 40.10 H ATOM 1310 HZ3 LYS A 312 31.928 -42.226 15.760 1.00 40.10 H ATOM 1311 N HIS A 313 30.940 -39.332 9.077 1.00 22.45 N ANISOU 1311 N HIS A 313 1931 3233 3365 -796 -257 733 N ATOM 1312 CA HIS A 313 32.195 -38.744 8.603 1.00 27.58 C ANISOU 1312 CA HIS A 313 2817 3726 3938 -704 -74 615 C ATOM 1313 C HIS A 313 32.095 -37.956 7.361 1.00 31.82 C ANISOU 1313 C HIS A 313 3327 4305 4458 -910 363 545 C ATOM 1314 O HIS A 313 33.124 -37.652 6.717 1.00 34.22 O ANISOU 1314 O HIS A 313 3120 5084 4796 -877 568 254 O ATOM 1315 CB HIS A 313 33.237 -39.840 8.453 1.00 29.45 C ANISOU 1315 CB HIS A 313 3218 3840 4130 -355 -157 629 C ATOM 1316 CG HIS A 313 33.478 -40.542 9.743 1.00 31.49 C ANISOU 1316 CG HIS A 313 3676 4234 4057 -257 98 367 C ATOM 1317 ND1 HIS A 313 33.956 -39.882 10.858 1.00 35.51 N ANISOU 1317 ND1 HIS A 313 4136 4576 4780 -108 133 -76 N ATOM 1318 CD2 HIS A 313 33.209 -41.810 10.138 1.00 32.82 C ANISOU 1318 CD2 HIS A 313 3993 4152 4326 153 -102 399 C ATOM 1319 CE1 HIS A 313 34.026 -40.731 11.870 1.00 34.39 C ANISOU 1319 CE1 HIS A 313 4175 4419 4473 27 -124 -33 C ATOM 1320 NE2 HIS A 313 33.572 -41.906 11.461 1.00 36.35 N ANISOU 1320 NE2 HIS A 313 4406 4488 4916 101 148 -107 N ATOM 1321 H HIS A 313 30.654 -40.010 8.633 1.00 26.95 H ATOM 1322 HA HIS A 313 32.520 -38.135 9.298 1.00 33.12 H ATOM 1323 HB2 HIS A 313 32.927 -40.491 7.805 1.00 35.35 H ATOM 1324 HB3 HIS A 313 34.074 -39.447 8.159 1.00 35.35 H ATOM 1325 HD2 HIS A 313 32.865 -42.493 9.608 1.00 39.40 H ATOM 1326 HE1 HIS A 313 34.336 -40.534 12.724 1.00 41.28 H ATOM 1327 N GLY A 314 30.882 -37.512 7.064 1.00 30.08 N ANISOU 1327 N GLY A 314 3185 3712 4533 -1160 3 1172 N ATOM 1328 CA GLY A 314 30.661 -36.698 5.909 1.00 27.10 C ANISOU 1328 CA GLY A 314 3011 3405 3880 -1370 -262 765 C ATOM 1329 C GLY A 314 29.918 -37.475 4.851 1.00 22.46 C ANISOU 1329 C GLY A 314 2184 2779 3571 -1220 244 631 C ATOM 1330 O GLY A 314 29.951 -38.684 4.805 1.00 23.37 O ANISOU 1330 O GLY A 314 1762 2652 4466 -719 294 613 O ATOM 1331 H GLY A 314 30.174 -37.676 7.525 1.00 36.11 H ATOM 1332 HA2 GLY A 314 30.137 -35.918 6.151 1.00 32.53 H ATOM 1333 HA3 GLY A 314 31.510 -36.405 5.545 1.00 32.53 H ATOM 1334 N GLY A 315 29.271 -36.744 4.011 1.00 22.08 N ANISOU 1334 N GLY A 315 2014 3004 3372 -961 10 570 N ATOM 1335 CA GLY A 315 28.486 -37.361 2.969 1.00 18.51 C ANISOU 1335 CA GLY A 315 1938 2101 2996 -550 262 355 C ATOM 1336 C GLY A 315 27.119 -37.825 3.506 1.00 14.79 C ANISOU 1336 C GLY A 315 1488 1611 2519 -338 700 112 C ATOM 1337 O GLY A 315 26.753 -37.600 4.701 1.00 17.07 O ANISOU 1337 O GLY A 315 1763 1875 2849 -503 335 199 O ATOM 1338 H GLY A 315 29.260 -35.884 4.010 1.00 26.51 H ATOM 1339 HA2 GLY A 315 28.339 -36.726 2.250 1.00 22.23 H ATOM 1340 HA3 GLY A 315 28.959 -38.129 2.614 1.00 22.23 H ATOM 1341 N TYR A 316 26.369 -38.405 2.594 1.00 15.02 N ANISOU 1341 N TYR A 316 1875 1506 2326 -265 757 -13 N ATOM 1342 CA TYR A 316 25.013 -38.823 2.897 1.00 13.21 C ANISOU 1342 CA TYR A 316 1336 1428 2255 -453 545 -224 C ATOM 1343 C TYR A 316 24.792 -40.194 2.289 1.00 14.60 C ANISOU 1343 C TYR A 316 1404 1606 2539 -76 844 -243 C ATOM 1344 O TYR A 316 25.425 -40.562 1.312 1.00 16.71 O ANISOU 1344 O TYR A 316 2066 1755 2527 -409 1233 -424 O ATOM 1345 CB TYR A 316 23.981 -37.876 2.219 1.00 15.76 C ANISOU 1345 CB TYR A 316 1836 1536 2616 -53 324 -288 C ATOM 1346 CG TYR A 316 23.959 -36.480 2.822 1.00 15.33 C ANISOU 1346 CG TYR A 316 2049 1497 2279 -204 -36 263 C ATOM 1347 CD1 TYR A 316 23.030 -36.169 3.837 1.00 15.39 C ANISOU 1347 CD1 TYR A 316 2216 1548 2085 183 -350 109 C ATOM 1348 CD2 TYR A 316 24.898 -35.510 2.483 1.00 18.16 C ANISOU 1348 CD2 TYR A 316 2550 1580 2770 -260 -193 423 C ATOM 1349 CE1 TYR A 316 23.017 -34.960 4.491 1.00 16.29 C ANISOU 1349 CE1 TYR A 316 2512 1608 2069 9 -377 -103 C ATOM 1350 CE2 TYR A 316 24.892 -34.260 3.097 1.00 18.31 C ANISOU 1350 CE2 TYR A 316 2458 1647 2851 -282 -731 207 C ATOM 1351 CZ TYR A 316 23.933 -33.973 4.091 1.00 18.12 C ANISOU 1351 CZ TYR A 316 2909 1485 2490 -20 -807 -120 C ATOM 1352 OH TYR A 316 23.940 -32.759 4.710 1.00 20.97 O ANISOU 1352 OH TYR A 316 3482 1684 2800 26 -1237 -265 O ATOM 1353 H TYR A 316 26.618 -38.569 1.787 1.00 18.04 H ATOM 1354 HA TYR A 316 24.859 -38.854 3.864 1.00 15.87 H ATOM 1355 HB2 TYR A 316 24.203 -37.792 1.279 1.00 18.93 H ATOM 1356 HB3 TYR A 316 23.094 -38.257 2.316 1.00 18.93 H ATOM 1357 HD1 TYR A 316 22.424 -36.823 4.101 1.00 18.49 H ATOM 1358 HD2 TYR A 316 25.528 -35.693 1.823 1.00 21.81 H ATOM 1359 HE1 TYR A 316 22.374 -34.776 5.138 1.00 19.56 H ATOM 1360 HE2 TYR A 316 25.511 -33.614 2.846 1.00 21.98 H ATOM 1361 HH TYR A 316 23.789 -32.165 4.165 1.00 25.17 H ATOM 1362 N AVAL A 317 23.889 -40.969 2.886 0.54 12.58 N ANISOU 1362 N AVAL A 317 1235 1405 2140 -165 542 -344 N ATOM 1363 N BVAL A 317 23.876 -40.941 2.892 0.46 12.81 N ANISOU 1363 N BVAL A 317 1345 1363 2158 -136 455 -137 N ATOM 1364 CA AVAL A 317 23.419 -42.212 2.294 0.54 12.82 C ANISOU 1364 CA AVAL A 317 1281 1224 2366 -111 895 -148 C ATOM 1365 CA BVAL A 317 23.403 -42.197 2.344 0.46 13.16 C ANISOU 1365 CA BVAL A 317 1436 1331 2234 0 858 -81 C ATOM 1366 C AVAL A 317 21.935 -42.065 1.994 0.54 11.62 C ANISOU 1366 C AVAL A 317 1227 1020 2167 -7 606 -247 C ATOM 1367 C BVAL A 317 21.954 -41.943 1.932 0.46 12.82 C ANISOU 1367 C BVAL A 317 1324 1221 2328 -196 538 -450 C ATOM 1368 O AVAL A 317 21.168 -41.482 2.770 0.54 10.48 O ANISOU 1368 O AVAL A 317 1153 1009 1819 146 93 -538 O ATOM 1369 O BVAL A 317 21.253 -41.156 2.563 0.46 13.24 O ANISOU 1369 O BVAL A 317 1712 1283 2036 32 513 71 O ATOM 1370 CB AVAL A 317 23.588 -43.438 3.230 0.54 15.87 C ANISOU 1370 CB AVAL A 317 1561 1383 3084 57 682 98 C ATOM 1371 CB BVAL A 317 23.541 -43.353 3.398 0.46 16.32 C ANISOU 1371 CB BVAL A 317 1658 1488 3054 416 823 -26 C ATOM 1372 CG1AVAL A 317 22.615 -43.393 4.385 0.54 13.65 C ANISOU 1372 CG1AVAL A 317 1439 1548 2200 239 852 158 C ATOM 1373 CG1BVAL A 317 22.754 -44.539 3.095 0.46 17.13 C ANISOU 1373 CG1BVAL A 317 2366 2058 2086 272 727 -135 C ATOM 1374 CG2AVAL A 317 23.407 -44.696 2.517 0.54 19.29 C ANISOU 1374 CG2AVAL A 317 1828 2153 3349 152 389 -2 C ATOM 1375 CG2BVAL A 317 24.961 -43.734 3.506 0.46 15.40 C ANISOU 1375 CG2BVAL A 317 1407 1876 2568 412 1020 603 C ATOM 1376 H AVAL A 317 23.529 -40.791 3.647 0.54 15.11 H ATOM 1377 H BVAL A 317 23.505 -40.732 3.640 0.46 15.38 H ATOM 1378 HA AVAL A 317 23.897 -42.384 1.456 0.54 15.40 H ATOM 1379 HA BVAL A 317 23.924 -42.430 1.547 0.46 15.81 H ATOM 1380 HB AVAL A 317 24.495 -43.430 3.601 0.54 19.05 H ATOM 1381 HB BVAL A 317 23.254 -43.018 4.273 0.46 19.59 H ATOM 1382 HG11AVAL A 317 22.751 -44.165 4.939 0.54 16.40 H ATOM 1383 HG11BVAL A 317 22.895 -45.192 3.784 0.46 20.57 H ATOM 1384 HG12AVAL A 317 22.771 -42.594 4.894 0.54 16.40 H ATOM 1385 HG12BVAL A 317 21.826 -44.297 3.058 0.46 20.57 H ATOM 1386 HG13AVAL A 317 21.720 -43.391 4.039 0.54 16.40 H ATOM 1387 HG13BVAL A 317 23.034 -44.892 2.247 0.46 20.57 H ATOM 1388 HG21AVAL A 317 23.520 -45.423 3.134 0.54 23.16 H ATOM 1389 HG21BVAL A 317 25.046 -44.441 4.150 0.46 18.49 H ATOM 1390 HG22AVAL A 317 22.523 -44.718 2.143 0.54 23.16 H ATOM 1391 HG22BVAL A 317 25.270 -44.034 2.648 0.46 18.49 H ATOM 1392 HG23AVAL A 317 24.061 -44.755 1.817 0.54 23.16 H ATOM 1393 HG23BVAL A 317 25.469 -42.970 3.789 0.46 18.49 H ATOM 1394 N TRP A 318 21.512 -42.564 0.850 1.00 12.27 N ANISOU 1394 N TRP A 318 1574 1256 1831 -155 647 -326 N ATOM 1395 CA TRP A 318 20.101 -42.659 0.521 1.00 11.47 C ANISOU 1395 CA TRP A 318 1540 1233 1586 -249 382 -312 C ATOM 1396 C TRP A 318 19.467 -43.770 1.316 1.00 11.43 C ANISOU 1396 C TRP A 318 1601 1146 1597 -147 479 -266 C ATOM 1397 O TRP A 318 20.009 -44.871 1.396 1.00 12.13 O ANISOU 1397 O TRP A 318 1594 1165 1848 -10 401 -254 O ATOM 1398 CB TRP A 318 19.866 -42.913 -0.977 1.00 13.69 C ANISOU 1398 CB TRP A 318 2113 1396 1692 -63 791 -38 C ATOM 1399 CG TRP A 318 20.168 -41.735 -1.849 1.00 14.59 C ANISOU 1399 CG TRP A 318 2459 1330 1756 -77 437 -196 C ATOM 1400 CD1 TRP A 318 21.317 -41.457 -2.544 1.00 16.42 C ANISOU 1400 CD1 TRP A 318 2568 1563 2109 -284 874 -193 C ATOM 1401 CD2 TRP A 318 19.267 -40.668 -2.140 1.00 13.89 C ANISOU 1401 CD2 TRP A 318 2413 1305 1558 -89 350 -120 C ATOM 1402 NE1 TRP A 318 21.169 -40.284 -3.213 1.00 17.86 N ANISOU 1402 NE1 TRP A 318 2967 1677 2141 -377 1254 100 N ATOM 1403 CE2 TRP A 318 19.925 -39.790 -2.997 1.00 15.78 C ANISOU 1403 CE2 TRP A 318 2550 1465 1981 -427 856 -109 C ATOM 1404 CE3 TRP A 318 17.956 -40.384 -1.760 1.00 14.13 C ANISOU 1404 CE3 TRP A 318 2242 1487 1638 -115 303 -225 C ATOM 1405 CZ2 TRP A 318 19.320 -38.612 -3.470 1.00 16.52 C ANISOU 1405 CZ2 TRP A 318 2947 1561 1769 -305 324 26 C ATOM 1406 CZ3 TRP A 318 17.377 -39.255 -2.219 1.00 16.03 C ANISOU 1406 CZ3 TRP A 318 2570 1794 1725 163 -111 -196 C ATOM 1407 CH2 TRP A 318 18.046 -38.372 -3.077 1.00 16.55 C ANISOU 1407 CH2 TRP A 318 2817 1656 1816 95 168 -65 C ATOM 1408 H ATRP A 318 22.031 -42.861 0.232 0.54 14.73 H ATOM 1409 H BTRP A 318 22.024 -42.948 0.275 0.46 14.73 H ATOM 1410 HA TRP A 318 19.657 -41.818 0.762 1.00 13.78 H ATOM 1411 HB2 TRP A 318 20.435 -43.645 -1.262 1.00 16.44 H ATOM 1412 HB3 TRP A 318 18.935 -43.149 -1.111 1.00 16.44 H ATOM 1413 HD1 TRP A 318 22.087 -41.979 -2.539 1.00 19.72 H ATOM 1414 HE1 TRP A 318 21.768 -39.919 -3.711 1.00 21.44 H ATOM 1415 HE3 TRP A 318 17.494 -40.955 -1.190 1.00 16.97 H ATOM 1416 HZ2 TRP A 318 19.805 -37.977 -3.946 1.00 19.84 H ATOM 1417 HZ3 TRP A 318 16.504 -39.061 -1.964 1.00 19.25 H ATOM 1418 HH2 TRP A 318 17.612 -37.605 -3.373 1.00 19.88 H ATOM 1419 N ALEU A 319 18.274 -43.559 1.793 0.47 10.21 N ANISOU 1419 N ALEU A 319 1374 1084 1422 -220 533 -262 N ATOM 1420 N BLEU A 319 18.314 -43.432 1.927 0.53 11.97 N ANISOU 1420 N BLEU A 319 1463 1285 1800 -25 39 202 N ATOM 1421 CA ALEU A 319 17.583 -44.634 2.445 0.47 10.64 C ANISOU 1421 CA ALEU A 319 1475 1223 1345 -392 523 -394 C ATOM 1422 CA BLEU A 319 17.501 -44.302 2.799 0.53 8.84 C ANISOU 1422 CA BLEU A 319 1034 1350 976 181 207 -145 C ATOM 1423 C ALEU A 319 16.102 -44.349 2.379 0.47 10.13 C ANISOU 1423 C ALEU A 319 1313 1106 1432 57 379 -172 C ATOM 1424 C BLEU A 319 16.045 -44.326 2.321 0.53 9.02 C ANISOU 1424 C BLEU A 319 1087 1050 1288 84 249 -100 C ATOM 1425 O ALEU A 319 15.677 -43.254 2.004 0.47 11.32 O ANISOU 1425 O ALEU A 319 1705 1504 1093 237 116 -284 O ATOM 1426 O BLEU A 319 15.547 -43.391 1.675 0.53 9.05 O ANISOU 1426 O BLEU A 319 1314 839 1286 -202 132 -151 O ATOM 1427 CB ALEU A 319 18.038 -44.888 3.892 0.47 12.52 C ANISOU 1427 CB ALEU A 319 1638 1377 1743 -109 537 -247 C ATOM 1428 CB BLEU A 319 17.413 -43.839 4.327 0.53 12.32 C ANISOU 1428 CB BLEU A 319 830 1615 2236 22 -65 -171 C ATOM 1429 CG ALEU A 319 18.419 -43.871 4.968 0.47 13.84 C ANISOU 1429 CG ALEU A 319 2539 1187 1534 -461 526 -431 C ATOM 1430 CG BLEU A 319 18.065 -44.487 5.483 0.53 20.00 C ANISOU 1430 CG BLEU A 319 2459 2303 2836 -245 673 -839 C ATOM 1431 CD1ALEU A 319 18.090 -42.408 4.551 0.47 15.26 C ANISOU 1431 CD1ALEU A 319 2079 1751 1968 -548 814 -473 C ATOM 1432 CD1BLEU A 319 19.334 -45.204 4.976 0.53 15.49 C ANISOU 1432 CD1BLEU A 319 2082 1923 1881 -23 52 -661 C ATOM 1433 CD2ALEU A 319 17.907 -44.205 6.409 0.47 14.57 C ANISOU 1433 CD2ALEU A 319 2221 1809 1505 -157 160 -258 C ATOM 1434 CD2BLEU A 319 18.398 -43.516 6.493 0.53 14.54 C ANISOU 1434 CD2BLEU A 319 2131 1952 1443 -875 66 -129 C ATOM 1435 H ALEU A 319 17.845 -42.814 1.756 0.47 12.27 H ATOM 1436 H BLEU A 319 17.965 -42.650 1.843 0.53 14.38 H ATOM 1437 HA ALEU A 319 17.746 -45.457 1.939 0.47 12.78 H ATOM 1438 HA BLEU A 319 17.855 -45.216 2.769 0.53 10.63 H ATOM 1439 HB2ALEU A 319 17.329 -45.412 4.296 0.47 15.04 H ATOM 1440 HB2BLEU A 319 17.728 -42.922 4.345 0.53 14.80 H ATOM 1441 HB3ALEU A 319 18.817 -45.462 3.818 0.47 15.04 H ATOM 1442 HB3BLEU A 319 16.468 -43.829 4.547 0.53 14.80 H ATOM 1443 HG ALEU A 319 19.386 -43.902 5.033 0.47 16.63 H ATOM 1444 HG BLEU A 319 17.468 -45.146 5.869 0.53 24.01 H ATOM 1445 HD11ALEU A 319 18.349 -41.816 5.262 0.47 18.32 H ATOM 1446 HD11BLEU A 319 19.769 -45.630 5.718 0.53 18.60 H ATOM 1447 HD12ALEU A 319 18.578 -42.194 3.752 0.47 18.32 H ATOM 1448 HD12BLEU A 319 19.082 -45.860 4.322 0.53 18.60 H ATOM 1449 HD13ALEU A 319 17.147 -42.334 4.390 0.47 18.32 H ATOM 1450 HD13BLEU A 319 19.922 -44.555 4.580 0.53 18.60 H ATOM 1451 HD21ALEU A 319 18.194 -43.513 7.010 0.47 17.49 H ATOM 1452 HD21BLEU A 319 18.819 -43.964 7.230 0.53 17.47 H ATOM 1453 HD22ALEU A 319 16.948 -44.252 6.397 0.47 17.49 H ATOM 1454 HD22BLEU A 319 18.998 -42.868 6.117 0.53 17.47 H ATOM 1455 HD23ALEU A 319 18.273 -45.049 6.682 0.47 17.49 H ATOM 1456 HD23BLEU A 319 17.592 -43.084 6.788 0.53 17.47 H ATOM 1457 N GLU A 320 15.341 -45.354 2.735 1.00 10.27 N ANISOU 1457 N GLU A 320 1339 1277 1288 -64 231 93 N ATOM 1458 CA GLU A 320 13.888 -45.256 2.906 1.00 11.27 C ANISOU 1458 CA GLU A 320 1558 1520 1204 -217 -70 35 C ATOM 1459 C GLU A 320 13.533 -45.843 4.266 1.00 10.25 C ANISOU 1459 C GLU A 320 1101 1375 1418 -63 42 -20 C ATOM 1460 O GLU A 320 14.224 -46.724 4.751 1.00 11.16 O ANISOU 1460 O GLU A 320 1071 1451 1717 178 273 168 O ATOM 1461 CB GLU A 320 13.248 -46.058 1.813 1.00 16.99 C ANISOU 1461 CB GLU A 320 2003 2678 1774 -627 -47 192 C ATOM 1462 CG GLU A 320 11.754 -46.026 1.618 1.00 23.65 C ANISOU 1462 CG GLU A 320 3036 3326 2626 -625 807 -35 C ATOM 1463 CD GLU A 320 11.450 -46.710 0.240 1.00 29.37 C ANISOU 1463 CD GLU A 320 3434 4203 3521 -37 -603 -63 C ATOM 1464 OE1 GLU A 320 10.868 -47.784 0.267 1.00 28.22 O ANISOU 1464 OE1 GLU A 320 3356 4389 2975 932 -346 -915 O ATOM 1465 OE2 GLU A 320 11.913 -46.229 -0.837 1.00 30.35 O ANISOU 1465 OE2 GLU A 320 3561 4583 3389 76 49 -933 O ATOM 1466 H AGLU A 320 15.645 -46.143 2.893 0.47 12.34 H ATOM 1467 H BGLU A 320 15.669 -46.125 2.926 0.53 12.34 H ATOM 1468 HA GLU A 320 13.591 -44.324 2.856 1.00 13.54 H ATOM 1469 HB2 GLU A 320 13.639 -45.767 0.974 1.00 20.40 H ATOM 1470 HB3 GLU A 320 13.484 -46.987 1.959 1.00 20.40 H ATOM 1471 HG2 GLU A 320 11.315 -46.525 2.324 1.00 28.40 H ATOM 1472 HG3 GLU A 320 11.441 -45.108 1.592 1.00 28.40 H ATOM 1473 N THR A 321 12.494 -45.309 4.893 1.00 10.21 N ANISOU 1473 N THR A 321 1132 1412 1337 40 5 -60 N ATOM 1474 CA THR A 321 12.090 -45.690 6.203 1.00 10.08 C ANISOU 1474 CA THR A 321 1060 1386 1384 19 27 65 C ATOM 1475 C THR A 321 10.613 -46.002 6.257 1.00 10.67 C ANISOU 1475 C THR A 321 907 1726 1421 63 69 85 C ATOM 1476 O THR A 321 9.771 -45.162 5.839 1.00 13.16 O ANISOU 1476 O THR A 321 1149 1865 1986 98 -110 231 O ATOM 1477 CB THR A 321 12.410 -44.569 7.204 1.00 10.65 C ANISOU 1477 CB THR A 321 1149 1537 1362 15 101 -53 C ATOM 1478 OG1 THR A 321 13.836 -44.368 7.245 1.00 11.37 O ANISOU 1478 OG1 THR A 321 1370 1358 1593 -49 98 33 O ATOM 1479 CG2 THR A 321 11.908 -44.889 8.603 1.00 12.53 C ANISOU 1479 CG2 THR A 321 1550 1593 1618 -155 151 -21 C ATOM 1480 H THR A 321 11.995 -44.698 4.550 1.00 12.27 H ATOM 1481 HA THR A 321 12.584 -46.492 6.473 1.00 12.11 H ATOM 1482 HB THR A 321 11.982 -43.749 6.911 1.00 12.80 H ATOM 1483 HG1 THR A 321 14.210 -45.058 7.481 1.00 13.66 H ATOM 1484 HG21 THR A 321 12.124 -44.171 9.202 1.00 15.05 H ATOM 1485 HG22 THR A 321 10.956 -45.009 8.590 1.00 15.05 H ATOM 1486 HG23 THR A 321 12.320 -45.696 8.922 1.00 15.05 H ATOM 1487 N GLN A 322 10.277 -47.159 6.784 1.00 10.02 N ANISOU 1487 N GLN A 322 906 1632 1268 51 69 -62 N ATOM 1488 CA GLN A 322 8.886 -47.465 7.115 1.00 10.89 C ANISOU 1488 CA GLN A 322 853 1791 1491 -63 -99 -35 C ATOM 1489 C GLN A 322 8.719 -47.133 8.619 1.00 10.08 C ANISOU 1489 C GLN A 322 757 1762 1312 -142 -7 -303 C ATOM 1490 O GLN A 322 9.412 -47.689 9.459 1.00 11.19 O ANISOU 1490 O GLN A 322 875 1968 1409 39 -94 93 O ATOM 1491 CB GLN A 322 8.599 -48.939 6.893 1.00 13.20 C ANISOU 1491 CB GLN A 322 1141 2348 1526 -440 49 -104 C ATOM 1492 CG GLN A 322 7.204 -49.224 7.318 1.00 21.54 C ANISOU 1492 CG GLN A 322 2302 3011 2870 -746 -583 -168 C ATOM 1493 CD GLN A 322 6.856 -50.582 7.153 1.00 27.60 C ANISOU 1493 CD GLN A 322 3309 3266 3909 -697 -132 -730 C ATOM 1494 OE1 GLN A 322 7.021 -51.189 6.016 1.00 33.86 O ANISOU 1494 OE1 GLN A 322 4585 3815 4464 -1544 -1034 -1820 O ATOM 1495 NE2 GLN A 322 6.373 -51.176 8.281 1.00 26.34 N ANISOU 1495 NE2 GLN A 322 3737 2847 3426 -755 312 47 N ATOM 1496 H GLN A 322 10.830 -47.792 6.965 1.00 12.03 H ATOM 1497 HA GLN A 322 8.271 -46.920 6.582 1.00 13.08 H ATOM 1498 HB2 GLN A 322 8.689 -49.153 5.952 1.00 15.86 H ATOM 1499 HB3 GLN A 322 9.204 -49.476 7.428 1.00 15.86 H ATOM 1500 HG2 GLN A 322 7.106 -49.001 8.257 1.00 25.86 H ATOM 1501 HG3 GLN A 322 6.594 -48.691 6.783 1.00 25.86 H ATOM 1502 HE21 GLN A 322 6.139 -52.004 8.264 1.00 31.63 H ATOM 1503 HE22 GLN A 322 6.303 -50.724 9.009 1.00 31.63 H ATOM 1504 N GLY A 323 7.765 -46.257 8.870 1.00 10.91 N ANISOU 1504 N GLY A 323 813 1808 1524 -7 -18 -89 N ATOM 1505 CA GLY A 323 7.455 -45.835 10.240 1.00 10.32 C ANISOU 1505 CA GLY A 323 767 1479 1676 135 -136 -255 C ATOM 1506 C GLY A 323 6.109 -46.380 10.689 1.00 9.90 C ANISOU 1506 C GLY A 323 591 1387 1784 -178 11 -318 C ATOM 1507 O GLY A 323 5.157 -46.394 9.919 1.00 10.60 O ANISOU 1507 O GLY A 323 637 1801 1591 -86 -139 -189 O ATOM 1508 H GLY A 323 7.275 -45.885 8.269 1.00 13.10 H ATOM 1509 HA2 GLY A 323 8.140 -46.160 10.845 1.00 12.40 H ATOM 1510 HA3 GLY A 323 7.432 -44.867 10.288 1.00 12.40 H ATOM 1511 N THR A 324 6.042 -46.722 11.975 1.00 9.27 N ANISOU 1511 N THR A 324 685 1368 1470 -100 -6 -159 N ATOM 1512 CA THR A 324 4.808 -47.214 12.551 1.00 9.78 C ANISOU 1512 CA THR A 324 983 1238 1493 -181 110 -186 C ATOM 1513 C THR A 324 4.674 -46.632 13.962 1.00 9.80 C ANISOU 1513 C THR A 324 705 1244 1776 -79 6 -81 C ATOM 1514 O THR A 324 5.591 -46.703 14.745 1.00 11.71 O ANISOU 1514 O THR A 324 901 1812 1738 8 175 -252 O ATOM 1515 CB THR A 324 4.908 -48.760 12.688 1.00 12.54 C ANISOU 1515 CB THR A 324 1314 1333 2116 -358 29 -354 C ATOM 1516 OG1 THR A 324 5.069 -49.345 11.415 1.00 14.15 O ANISOU 1516 OG1 THR A 324 1627 1480 2271 -266 -64 -399 O ATOM 1517 CG2 THR A 324 3.644 -49.340 13.340 1.00 16.53 C ANISOU 1517 CG2 THR A 324 1659 1678 2943 -389 -38 93 C ATOM 1518 H THR A 324 6.699 -46.677 12.528 1.00 11.14 H ATOM 1519 HA THR A 324 4.033 -46.968 12.004 1.00 11.75 H ATOM 1520 HB THR A 324 5.670 -48.985 13.245 1.00 15.06 H ATOM 1521 HG1 THR A 324 5.754 -49.064 11.061 1.00 17.00 H ATOM 1522 HG21 THR A 324 3.723 -50.294 13.416 1.00 19.85 H ATOM 1523 HG22 THR A 324 3.525 -48.966 14.216 1.00 19.85 H ATOM 1524 HG23 THR A 324 2.874 -49.133 12.804 1.00 19.85 H ATOM 1525 N VAL A 325 3.516 -46.053 14.264 1.00 10.21 N ANISOU 1525 N VAL A 325 823 1395 1661 -110 87 -74 N ATOM 1526 CA VAL A 325 3.283 -45.527 15.586 1.00 11.19 C ANISOU 1526 CA VAL A 325 955 1510 1787 -76 344 -166 C ATOM 1527 C VAL A 325 2.786 -46.674 16.480 1.00 11.37 C ANISOU 1527 C VAL A 325 834 1412 2074 -252 545 -80 C ATOM 1528 O VAL A 325 1.912 -47.449 16.082 1.00 13.27 O ANISOU 1528 O VAL A 325 1136 1547 2358 -377 324 -43 O ATOM 1529 CB VAL A 325 2.256 -44.367 15.629 1.00 12.75 C ANISOU 1529 CB VAL A 325 1137 1638 2068 4 47 -390 C ATOM 1530 CG1 VAL A 325 2.107 -43.809 17.029 1.00 14.61 C ANISOU 1530 CG1 VAL A 325 1562 1615 2372 -23 444 -464 C ATOM 1531 CG2 VAL A 325 2.667 -43.283 14.691 1.00 13.19 C ANISOU 1531 CG2 VAL A 325 1358 1526 2126 19 186 -2 C ATOM 1532 H VAL A 325 2.857 -45.957 13.719 1.00 12.27 H ATOM 1533 HA VAL A 325 4.130 -45.198 15.954 1.00 13.44 H ATOM 1534 HB VAL A 325 1.382 -44.702 15.341 1.00 15.31 H ATOM 1535 HG11 VAL A 325 1.465 -43.095 17.013 1.00 17.54 H ATOM 1536 HG12 VAL A 325 1.806 -44.508 17.613 1.00 17.54 H ATOM 1537 HG13 VAL A 325 2.958 -43.477 17.325 1.00 17.54 H ATOM 1538 HG21 VAL A 325 2.021 -42.574 14.731 1.00 15.84 H ATOM 1539 HG22 VAL A 325 3.531 -42.955 14.953 1.00 15.84 H ATOM 1540 HG23 VAL A 325 2.708 -43.640 13.801 1.00 15.84 H ATOM 1541 N ILE A 326 3.358 -46.737 17.670 1.00 11.46 N ANISOU 1541 N ILE A 326 1148 1369 1836 -194 566 -178 N ATOM 1542 CA ILE A 326 2.935 -47.694 18.694 1.00 13.11 C ANISOU 1542 CA ILE A 326 1547 1340 2096 -141 912 121 C ATOM 1543 C ILE A 326 2.123 -46.937 19.702 1.00 15.33 C ANISOU 1543 C ILE A 326 1629 1396 2799 -316 1359 -130 C ATOM 1544 O ILE A 326 2.525 -45.906 20.179 1.00 16.28 O ANISOU 1544 O ILE A 326 1986 1689 2510 -505 1323 -495 O ATOM 1545 CB ILE A 326 4.155 -48.349 19.349 1.00 15.40 C ANISOU 1545 CB ILE A 326 2230 1629 1993 -184 866 156 C ATOM 1546 CG1 ILE A 326 5.088 -48.949 18.289 1.00 15.40 C ANISOU 1546 CG1 ILE A 326 2027 1786 2038 316 1005 143 C ATOM 1547 CG2 ILE A 326 3.718 -49.317 20.447 1.00 19.73 C ANISOU 1547 CG2 ILE A 326 2688 1995 2815 -325 1474 488 C ATOM 1548 CD1 ILE A 326 4.512 -50.028 17.444 1.00 16.98 C ANISOU 1548 CD1 ILE A 326 2185 1882 2382 194 863 -167 C ATOM 1549 H ILE A 326 4.005 -46.228 17.919 1.00 13.77 H ATOM 1550 HA ILE A 326 2.376 -48.391 18.291 1.00 15.75 H ATOM 1551 HB ILE A 326 4.652 -47.640 19.786 1.00 18.49 H ATOM 1552 HG12 ILE A 326 5.371 -48.238 17.694 1.00 18.49 H ATOM 1553 HG13 ILE A 326 5.863 -49.319 18.740 1.00 18.49 H ATOM 1554 HG21 ILE A 326 4.497 -49.714 20.842 1.00 23.70 H ATOM 1555 HG22 ILE A 326 3.224 -48.832 21.112 1.00 23.70 H ATOM 1556 HG23 ILE A 326 3.163 -49.999 20.060 1.00 23.70 H ATOM 1557 HD11 ILE A 326 5.179 -50.327 16.822 1.00 20.38 H ATOM 1558 HD12 ILE A 326 4.241 -50.756 18.009 1.00 20.38 H ATOM 1559 HD13 ILE A 326 3.753 -49.682 16.970 1.00 20.38 H ATOM 1560 N TYR A 327 0.929 -47.438 20.001 1.00 18.93 N ANISOU 1560 N TYR A 327 1969 1707 3517 -363 1709 -502 N ATOM 1561 CA TYR A 327 -0.044 -46.798 20.863 1.00 22.47 C ANISOU 1561 CA TYR A 327 2649 2226 3664 -534 1888 -483 C ATOM 1562 C TYR A 327 -0.378 -47.583 22.035 1.00 25.70 C ANISOU 1562 C TYR A 327 3625 2155 3986 -831 2354 -827 C ATOM 1563 O TYR A 327 -0.255 -48.824 22.090 1.00 27.56 O ANISOU 1563 O TYR A 327 4197 2168 4106 -370 2858 -334 O ATOM 1564 CB TYR A 327 -1.381 -46.649 20.144 1.00 26.79 C ANISOU 1564 CB TYR A 327 2669 3158 4351 -75 1667 -973 C ATOM 1565 CG TYR A 327 -1.355 -45.797 18.984 1.00 23.35 C ANISOU 1565 CG TYR A 327 1844 2827 4201 -4 1352 -633 C ATOM 1566 CD1 TYR A 327 -1.107 -46.339 17.751 1.00 24.89 C ANISOU 1566 CD1 TYR A 327 1906 3240 4311 57 863 -910 C ATOM 1567 CD2 TYR A 327 -1.464 -44.406 19.089 1.00 25.51 C ANISOU 1567 CD2 TYR A 327 2576 2955 4163 53 1780 -778 C ATOM 1568 CE1 TYR A 327 -1.080 -45.559 16.640 1.00 22.35 C ANISOU 1568 CE1 TYR A 327 1710 2982 3801 642 83 -781 C ATOM 1569 CE2 TYR A 327 -1.398 -43.619 17.961 1.00 22.88 C ANISOU 1569 CE2 TYR A 327 1911 3001 3780 120 1014 -647 C ATOM 1570 CZ TYR A 327 -1.119 -44.184 16.781 1.00 22.98 C ANISOU 1570 CZ TYR A 327 1785 2814 4134 302 419 -1095 C ATOM 1571 OH TYR A 327 -1.088 -43.436 15.666 1.00 24.83 O ANISOU 1571 OH TYR A 327 1885 2862 4687 206 42 -585 O ATOM 1572 H TYR A 327 0.652 -48.192 19.696 1.00 22.73 H ATOM 1573 HA TYR A 327 0.275 -45.915 21.143 1.00 26.98 H ATOM 1574 HB2 TYR A 327 -1.676 -47.527 19.855 1.00 32.16 H ATOM 1575 HB3 TYR A 327 -2.026 -46.278 20.765 1.00 32.16 H ATOM 1576 HD1 TYR A 327 -1.031 -47.262 17.663 1.00 29.88 H ATOM 1577 HD2 TYR A 327 -1.600 -44.014 19.921 1.00 30.63 H ATOM 1578 HE1 TYR A 327 -0.899 -45.937 15.810 1.00 26.84 H ATOM 1579 HE2 TYR A 327 -1.463 -42.694 18.033 1.00 27.47 H ATOM 1580 HH TYR A 327 -0.432 -42.944 15.677 1.00 29.81 H ATOM 1581 N ASN A 328 -0.942 -46.807 22.910 1.00 25.63 N ANISOU 1581 N ASN A 328 3310 2436 3995 -604 2560 -462 N ATOM 1582 CA ASN A 328 -1.952 -47.370 23.830 1.00 21.91 C ANISOU 1582 CA ASN A 328 2079 2952 3292 -85 -228 140 C ATOM 1583 C ASN A 328 -3.293 -47.714 23.183 1.00 17.49 C ANISOU 1583 C ASN A 328 1942 2527 2178 164 250 761 C ATOM 1584 O ASN A 328 -4.087 -46.814 22.895 1.00 20.43 O ANISOU 1584 O ASN A 328 1931 2674 3159 532 764 731 O ATOM 1585 CB ASN A 328 -2.423 -46.485 24.999 1.00 18.75 C ANISOU 1585 CB ASN A 328 2126 3363 1636 -327 467 12 C ATOM 1586 CG ASN A 328 -2.778 -47.293 26.230 1.00 29.61 C ANISOU 1586 CG ASN A 328 3546 4224 3480 -241 -554 -131 C ATOM 1587 OD1 ASN A 328 -3.597 -48.186 26.191 1.00 30.12 O ANISOU 1587 OD1 ASN A 328 3983 3851 3611 37 -1490 -213 O ATOM 1588 ND2 ASN A 328 -2.083 -47.013 27.324 1.00 39.04 N ANISOU 1588 ND2 ASN A 328 4858 5245 4732 -484 -46 -367 N ATOM 1589 H ASN A 328 -0.781 -45.968 23.011 1.00 30.78 H ATOM 1590 HA ASN A 328 -1.589 -48.196 24.214 1.00 26.30 H ATOM 1591 HB2 ASN A 328 -1.712 -45.870 25.238 1.00 22.52 H ATOM 1592 HB3 ASN A 328 -3.212 -45.992 24.725 1.00 22.52 H ATOM 1593 HD21 ASN A 328 -2.262 -47.498 28.156 1.00 46.87 H ATOM 1594 HD22 ASN A 328 -1.390 -46.320 27.300 1.00 46.87 H ATOM 1595 N PRO A 329 -3.634 -48.987 23.190 1.00 24.77 N ANISOU 1595 N PRO A 329 2193 2587 4631 -60 1097 1198 N ATOM 1596 CA PRO A 329 -4.964 -49.373 22.695 1.00 27.35 C ANISOU 1596 CA PRO A 329 2878 3051 4462 -238 911 -418 C ATOM 1597 C PRO A 329 -6.194 -48.767 23.459 1.00 24.33 C ANISOU 1597 C PRO A 329 2303 3197 3745 -116 607 666 C ATOM 1598 O PRO A 329 -7.321 -48.524 22.845 1.00 27.73 O ANISOU 1598 O PRO A 329 2231 3990 4316 -370 503 727 O ATOM 1599 CB PRO A 329 -4.922 -50.903 22.889 1.00 29.21 C ANISOU 1599 CB PRO A 329 3499 3435 4166 -32 481 255 C ATOM 1600 CG PRO A 329 -3.991 -50.959 24.190 1.00 27.95 C ANISOU 1600 CG PRO A 329 3208 3311 4103 57 283 1205 C ATOM 1601 CD PRO A 329 -2.908 -50.132 23.784 1.00 24.31 C ANISOU 1601 CD PRO A 329 2493 2345 4398 584 236 1164 C ATOM 1602 HA PRO A 329 -5.043 -49.171 21.739 1.00 32.83 H ATOM 1603 HB2 PRO A 329 -5.809 -51.252 23.066 1.00 35.07 H ATOM 1604 HB3 PRO A 329 -4.504 -51.335 22.128 1.00 35.07 H ATOM 1605 HG2 PRO A 329 -4.456 -50.585 24.955 1.00 33.56 H ATOM 1606 HG3 PRO A 329 -3.700 -51.868 24.358 1.00 33.56 H ATOM 1607 HD2 PRO A 329 -2.385 -49.848 24.550 1.00 29.19 H ATOM 1608 HD3 PRO A 329 -2.364 -50.579 23.117 1.00 29.19 H ATOM 1609 N ARG A 330 -5.965 -48.502 24.754 1.00 25.15 N ANISOU 1609 N ARG A 330 2502 3230 3824 509 1144 1409 N ATOM 1610 CA ARG A 330 -7.034 -48.078 25.591 1.00 25.59 C ANISOU 1610 CA ARG A 330 2983 3437 3303 1184 704 578 C ATOM 1611 C ARG A 330 -7.720 -46.817 25.125 1.00 21.69 C ANISOU 1611 C ARG A 330 2101 2704 3437 651 594 775 C ATOM 1612 O ARG A 330 -8.925 -46.614 25.283 1.00 23.20 O ANISOU 1612 O ARG A 330 2106 3227 3481 536 585 171 O ATOM 1613 CB ARG A 330 -6.559 -47.792 27.028 1.00 39.89 C ANISOU 1613 CB ARG A 330 4853 5059 5245 602 227 19 C ATOM 1614 CG ARG A 330 -5.765 -48.884 27.735 1.00 49.49 C ANISOU 1614 CG ARG A 330 6158 6283 6362 302 164 -69 C ATOM 1615 CD ARG A 330 -4.925 -48.243 28.841 1.00 54.37 C ANISOU 1615 CD ARG A 330 6856 6904 6897 93 293 -192 C ATOM 1616 NE ARG A 330 -5.598 -47.061 29.393 1.00 55.76 N ANISOU 1616 NE ARG A 330 7129 7076 6983 -70 36 -270 N ATOM 1617 CZ ARG A 330 -5.236 -45.786 29.212 1.00 55.51 C ANISOU 1617 CZ ARG A 330 7081 7023 6987 63 59 163 C ATOM 1618 NH1 ARG A 330 -4.165 -45.460 28.484 1.00 52.99 N ANISOU 1618 NH1 ARG A 330 6721 6954 6457 189 283 220 N ATOM 1619 NH2 ARG A 330 -5.949 -44.820 29.797 1.00 58.03 N ANISOU 1619 NH2 ARG A 330 7332 7366 7352 264 -307 229 N ATOM 1620 H ARG A 330 -5.202 -48.566 25.145 1.00 30.20 H ATOM 1621 HA ARG A 330 -7.706 -48.789 25.631 1.00 30.72 H ATOM 1622 HB2 ARG A 330 -5.998 -47.001 27.006 1.00 47.88 H ATOM 1623 HB3 ARG A 330 -7.341 -47.612 27.572 1.00 47.88 H ATOM 1624 HG2 ARG A 330 -6.372 -49.525 28.136 1.00 59.40 H ATOM 1625 HG3 ARG A 330 -5.171 -49.319 27.104 1.00 59.40 H ATOM 1626 HD2 ARG A 330 -4.794 -48.884 29.557 1.00 65.26 H ATOM 1627 HD3 ARG A 330 -4.070 -47.966 28.476 1.00 65.26 H ATOM 1628 HE ARG A 330 -6.381 -47.220 29.944 1.00 66.93 H ATOM 1629 HH11 ARG A 330 -3.697 -46.076 28.108 1.00 63.60 H ATOM 1630 HH12 ARG A 330 -3.949 -44.634 28.383 1.00 63.60 H ATOM 1631 HH21 ARG A 330 -6.639 -45.021 30.269 1.00 69.65 H ATOM 1632 HH22 ARG A 330 -5.727 -43.997 29.689 1.00 69.65 H ATOM 1633 N ASN A 331 -6.851 -45.902 24.710 1.00 21.41 N ANISOU 1633 N ASN A 331 2342 2670 3122 119 784 555 N ATOM 1634 CA ASN A 331 -7.222 -44.496 24.494 1.00 20.08 C ANISOU 1634 CA ASN A 331 2043 2177 3408 261 1211 419 C ATOM 1635 C ASN A 331 -6.590 -43.956 23.207 1.00 22.27 C ANISOU 1635 C ASN A 331 2345 2615 3503 636 1071 403 C ATOM 1636 O ASN A 331 -6.721 -42.758 22.890 1.00 23.19 O ANISOU 1636 O ASN A 331 2097 2878 3837 605 524 653 O ATOM 1637 CB ASN A 331 -6.904 -43.569 25.660 1.00 22.38 C ANISOU 1637 CB ASN A 331 2341 3270 2891 670 893 -112 C ATOM 1638 CG ASN A 331 -5.426 -43.532 26.036 1.00 24.48 C ANISOU 1638 CG ASN A 331 2271 3776 3255 394 750 -298 C ATOM 1639 OD1 ASN A 331 -4.564 -44.044 25.351 1.00 26.35 O ANISOU 1639 OD1 ASN A 331 2690 3631 3691 975 822 -658 O ATOM 1640 ND2 ASN A 331 -5.119 -42.780 27.063 1.00 27.04 N ANISOU 1640 ND2 ASN A 331 3276 3899 3099 356 1071 -441 N ATOM 1641 H ASN A 331 -6.024 -46.068 24.542 1.00 25.70 H ATOM 1642 HA ASN A 331 -8.193 -44.463 24.367 1.00 24.11 H ATOM 1643 HB2 ASN A 331 -7.172 -42.668 25.424 1.00 26.87 H ATOM 1644 HB3 ASN A 331 -7.400 -43.866 26.439 1.00 26.87 H ATOM 1645 HD21 ASN A 331 -4.188 -42.710 27.359 1.00 32.46 H ATOM 1646 HD22 ASN A 331 -5.822 -42.286 27.536 1.00 32.46 H ATOM 1647 N LEU A 332 -5.953 -44.812 22.374 1.00 25.96 N ANISOU 1647 N LEU A 332 3126 3436 3303 751 1395 924 N ATOM 1648 CA LEU A 332 -5.216 -44.431 21.090 1.00 29.71 C ANISOU 1648 CA LEU A 332 3525 3729 4034 -185 -90 349 C ATOM 1649 C LEU A 332 -4.167 -43.319 21.354 1.00 22.01 C ANISOU 1649 C LEU A 332 2829 3195 2340 -147 610 334 C ATOM 1650 O LEU A 332 -3.830 -42.583 20.454 1.00 27.13 O ANISOU 1650 O LEU A 332 3112 3447 3749 -104 558 1024 O ATOM 1651 CB LEU A 332 -6.154 -44.054 19.915 0.50 20.00 C ATOM 1652 CG LEU A 332 -6.320 -44.331 18.368 0.50 20.00 C ATOM 1653 CD1 LEU A 332 -7.326 -43.319 17.668 0.50 20.00 C ATOM 1654 CD2 LEU A 332 -5.351 -44.833 17.263 0.50 20.00 C ATOM 1655 H LEU A 332 -5.962 -45.649 22.562 1.00 31.17 H ATOM 1656 HA LEU A 332 -4.707 -45.177 20.709 1.00 35.66 H ATOM 1657 N GLN A 333 -3.646 -43.223 22.573 1.00 21.21 N ANISOU 1657 N GLN A 333 2365 2883 2809 -40 848 -84 N ATOM 1658 CA GLN A 333 -2.557 -42.308 22.898 1.00 21.33 C ANISOU 1658 CA GLN A 333 2148 2793 3164 -29 683 -97 C ATOM 1659 C GLN A 333 -1.244 -42.825 22.208 1.00 21.29 C ANISOU 1659 C GLN A 333 1920 2644 3523 241 987 -205 C ATOM 1660 O GLN A 333 -0.794 -43.962 22.480 1.00 20.14 O ANISOU 1660 O GLN A 333 1746 2415 3490 186 528 -90 O ATOM 1661 CB GLN A 333 -2.325 -42.382 24.381 1.00 26.60 C ANISOU 1661 CB GLN A 333 3161 3655 3291 -27 890 -1640 C ATOM 1662 CG GLN A 333 -1.078 -41.505 24.713 1.00 32.64 C ANISOU 1662 CG GLN A 333 4150 4385 3865 -573 11 -617 C ATOM 1663 CD GLN A 333 -0.328 -41.950 25.973 1.00 41.71 C ANISOU 1663 CD GLN A 333 5118 5202 5528 -6 81 -93 C ATOM 1664 OE1 GLN A 333 0.303 -43.007 25.987 1.00 45.22 O ANISOU 1664 OE1 GLN A 333 5683 5536 5964 241 327 -476 O ATOM 1665 NE2 GLN A 333 -0.395 -41.125 27.046 1.00 43.00 N ANISOU 1665 NE2 GLN A 333 5469 5515 5355 161 247 -439 N ATOM 1666 H GLN A 333 -3.914 -43.675 23.254 1.00 25.46 H ATOM 1667 HA GLN A 333 -2.758 -41.389 22.622 1.00 25.61 H ATOM 1668 HB2 GLN A 333 -3.094 -42.029 24.855 1.00 31.94 H ATOM 1669 HB3 GLN A 333 -2.145 -43.298 24.643 1.00 31.94 H ATOM 1670 HG2 GLN A 333 -0.458 -41.549 23.968 1.00 39.18 H ATOM 1671 HG3 GLN A 333 -1.366 -40.589 24.847 1.00 39.18 H ATOM 1672 HE21 GLN A 333 0.010 -41.334 27.775 1.00 51.62 H ATOM 1673 HE22 GLN A 333 -0.843 -40.393 26.998 1.00 51.62 H ATOM 1674 N PRO A 334 -0.537 -42.011 21.387 1.00 22.70 N ANISOU 1674 N PRO A 334 2292 2397 3937 -217 1331 -529 N ATOM 1675 CA PRO A 334 0.728 -42.502 20.816 1.00 21.58 C ANISOU 1675 CA PRO A 334 2308 2558 3332 -572 1287 -592 C ATOM 1676 C PRO A 334 1.826 -42.656 21.869 1.00 20.19 C ANISOU 1676 C PRO A 334 2519 2384 2768 -462 1355 -1334 C ATOM 1677 O PRO A 334 2.068 -41.750 22.665 1.00 26.49 O ANISOU 1677 O PRO A 334 3432 2708 3927 5 735 -1249 O ATOM 1678 CB PRO A 334 1.096 -41.436 19.816 1.00 23.40 C ANISOU 1678 CB PRO A 334 2851 2774 3265 -443 1400 -687 C ATOM 1679 CG PRO A 334 0.342 -40.211 20.272 1.00 27.06 C ANISOU 1679 CG PRO A 334 3239 3372 3671 302 1634 -414 C ATOM 1680 CD PRO A 334 -0.875 -40.632 20.973 1.00 25.80 C ANISOU 1680 CD PRO A 334 3217 3009 3578 115 1399 -387 C ATOM 1681 HA PRO A 334 0.591 -43.355 20.354 1.00 25.91 H ATOM 1682 HB2 PRO A 334 2.053 -41.280 19.838 1.00 28.09 H ATOM 1683 HB3 PRO A 334 0.810 -41.706 18.929 1.00 28.09 H ATOM 1684 HG2 PRO A 334 0.908 -39.698 20.870 1.00 32.49 H ATOM 1685 HG3 PRO A 334 0.110 -39.677 19.496 1.00 32.49 H ATOM 1686 HD2 PRO A 334 -1.033 -40.072 21.749 1.00 30.98 H ATOM 1687 HD3 PRO A 334 -1.634 -40.633 20.369 1.00 30.98 H ATOM 1688 N GLN A 335 2.580 -43.741 21.748 1.00 23.40 N ANISOU 1688 N GLN A 335 3049 2943 2898 -1039 1714 -1197 N ATOM 1689 CA GLN A 335 3.680 -44.036 22.650 1.00 19.32 C ANISOU 1689 CA GLN A 335 2950 2948 1444 -874 1013 -360 C ATOM 1690 C GLN A 335 5.112 -43.782 22.098 1.00 21.39 C ANISOU 1690 C GLN A 335 3205 2533 2390 -1292 1084 -400 C ATOM 1691 O GLN A 335 5.957 -43.208 22.765 1.00 23.40 O ANISOU 1691 O GLN A 335 3338 3226 2326 -1422 1150 -857 O ATOM 1692 CB GLN A 335 3.622 -45.454 23.176 1.00 28.40 C ANISOU 1692 CB GLN A 335 3678 3973 3141 -498 1118 -26 C ATOM 1693 CG GLN A 335 2.333 -45.649 24.010 1.00 40.65 C ANISOU 1693 CG GLN A 335 5074 5211 5159 -234 185 419 C ATOM 1694 CD GLN A 335 2.569 -46.373 25.349 1.00 45.47 C ANISOU 1694 CD GLN A 335 5668 5971 5638 -152 159 548 C ATOM 1695 OE1 GLN A 335 3.724 -46.660 25.760 1.00 42.22 O ANISOU 1695 OE1 GLN A 335 5289 5688 5063 -393 884 -103 O ATOM 1696 NE2 GLN A 335 1.456 -46.689 26.035 1.00 51.33 N ANISOU 1696 NE2 GLN A 335 6437 6539 6525 42 84 4 N ATOM 1697 H GLN A 335 2.469 -44.334 21.135 1.00 28.09 H ATOM 1698 HA GLN A 335 3.580 -43.448 23.428 1.00 23.20 H ATOM 1699 HB2 GLN A 335 3.607 -46.077 22.433 1.00 34.10 H ATOM 1700 HB3 GLN A 335 4.389 -45.621 23.747 1.00 34.10 H ATOM 1701 HG2 GLN A 335 1.952 -44.779 24.206 1.00 48.79 H ATOM 1702 HG3 GLN A 335 1.703 -46.176 23.494 1.00 48.79 H ATOM 1703 HE21 GLN A 335 1.518 -47.095 26.790 1.00 61.61 H ATOM 1704 HE22 GLN A 335 0.683 -46.486 25.718 1.00 61.61 H ATOM 1705 N CYS A 336 5.376 -44.262 20.888 1.00 16.97 N ANISOU 1705 N CYS A 336 2575 2068 1806 -988 1062 -456 N ATOM 1706 CA CYS A 336 6.645 -44.096 20.204 1.00 14.99 C ANISOU 1706 CA CYS A 336 2098 1881 1716 -601 197 -216 C ATOM 1707 C CYS A 336 6.468 -44.450 18.779 1.00 11.25 C ANISOU 1707 C CYS A 336 1579 1246 1449 -561 220 -112 C ATOM 1708 O CYS A 336 5.391 -44.876 18.350 1.00 12.80 O ANISOU 1708 O CYS A 336 1419 1700 1745 -554 443 -227 O ATOM 1709 CB CYS A 336 7.736 -44.992 20.784 1.00 17.12 C ANISOU 1709 CB CYS A 336 2334 2324 1847 -709 76 76 C ATOM 1710 SG CYS A 336 7.425 -46.732 20.802 1.00 20.13 S ANISOU 1710 SG CYS A 336 2831 1837 2981 -428 239 387 S ATOM 1711 H CYS A 336 4.804 -44.707 20.425 1.00 20.38 H ATOM 1712 HA CYS A 336 6.936 -43.162 20.264 1.00 18.00 H ATOM 1713 HB2 CYS A 336 8.546 -44.853 20.268 1.00 20.56 H ATOM 1714 HB3 CYS A 336 7.892 -44.721 21.702 1.00 20.56 H ATOM 1715 HG CYS A 336 7.236 -47.155 19.545 1.00 24.17 H ATOM 1716 N ILE A 337 7.505 -44.142 17.992 1.00 10.45 N ANISOU 1716 N ILE A 337 1300 1275 1397 -301 166 -228 N ATOM 1717 CA ILE A 337 7.581 -44.474 16.576 1.00 9.72 C ANISOU 1717 CA ILE A 337 1029 1410 1255 -82 20 -227 C ATOM 1718 C ILE A 337 8.616 -45.547 16.376 1.00 9.32 C ANISOU 1718 C ILE A 337 1051 1255 1234 -40 85 -283 C ATOM 1719 O ILE A 337 9.763 -45.390 16.805 1.00 10.71 O ANISOU 1719 O ILE A 337 1016 1442 1611 -184 -170 -306 O ATOM 1720 CB ILE A 337 7.861 -43.223 15.752 1.00 9.70 C ANISOU 1720 CB ILE A 337 1048 1579 1057 -48 169 -169 C ATOM 1721 CG1 ILE A 337 6.674 -42.237 15.824 1.00 12.15 C ANISOU 1721 CG1 ILE A 337 1425 1569 1624 154 329 -34 C ATOM 1722 CG2 ILE A 337 8.230 -43.559 14.316 1.00 12.50 C ANISOU 1722 CG2 ILE A 337 1438 1729 1584 183 66 51 C ATOM 1723 CD1 ILE A 337 6.984 -40.835 15.349 1.00 12.72 C ANISOU 1723 CD1 ILE A 337 1595 1425 1814 -17 298 -25 C ATOM 1724 H ILE A 337 8.201 -43.724 18.274 1.00 12.56 H ATOM 1725 HA ILE A 337 6.717 -44.835 16.289 1.00 11.68 H ATOM 1726 HB ILE A 337 8.627 -42.782 16.149 1.00 11.65 H ATOM 1727 HG12 ILE A 337 5.953 -42.580 15.274 1.00 14.60 H ATOM 1728 HG13 ILE A 337 6.380 -42.175 16.746 1.00 14.60 H ATOM 1729 HG21 ILE A 337 8.396 -42.743 13.837 1.00 15.02 H ATOM 1730 HG22 ILE A 337 9.019 -44.106 14.316 1.00 15.02 H ATOM 1731 HG23 ILE A 337 7.501 -44.035 13.910 1.00 15.02 H ATOM 1732 HD11 ILE A 337 6.193 -40.296 15.431 1.00 15.28 H ATOM 1733 HD12 ILE A 337 7.686 -40.469 15.892 1.00 15.28 H ATOM 1734 HD13 ILE A 337 7.263 -40.871 14.432 1.00 15.28 H ATOM 1735 N AMET A 338 8.271 -46.628 15.675 0.28 10.07 N ANISOU 1735 N AMET A 338 1050 1305 1473 -100 72 -342 N ATOM 1736 N BMET A 338 8.235 -46.597 15.674 0.31 10.10 N ANISOU 1736 N BMET A 338 992 1311 1534 -113 124 -338 N ATOM 1737 N CMET A 338 8.260 -46.652 15.727 0.41 9.77 N ANISOU 1737 N CMET A 338 796 1337 1578 97 -44 -300 N ATOM 1738 CA AMET A 338 9.187 -47.744 15.396 0.28 10.54 C ANISOU 1738 CA AMET A 338 1219 1422 1366 -56 31 -351 C ATOM 1739 CA BMET A 338 9.193 -47.568 15.228 0.31 10.69 C ANISOU 1739 CA BMET A 338 1265 1395 1402 -11 -338 -252 C ATOM 1740 CA CMET A 338 9.216 -47.694 15.360 0.41 10.56 C ANISOU 1740 CA CMET A 338 1097 1425 1491 164 -84 -471 C ATOM 1741 C AMET A 338 9.519 -47.710 13.887 0.28 9.93 C ANISOU 1741 C AMET A 338 857 1380 1537 -10 -309 -360 C ATOM 1742 C BMET A 338 9.515 -47.283 13.803 0.31 10.39 C ANISOU 1742 C BMET A 338 1041 1541 1367 -2 -284 -561 C ATOM 1743 C CMET A 338 9.515 -47.543 13.868 0.41 10.63 C ANISOU 1743 C CMET A 338 676 1551 1810 163 -309 -619 C ATOM 1744 O AMET A 338 8.608 -47.946 13.092 0.28 10.08 O ANISOU 1744 O AMET A 338 758 1347 1724 234 -115 -544 O ATOM 1745 O BMET A 338 8.645 -46.997 12.972 0.31 9.32 O ANISOU 1745 O BMET A 338 948 1320 1275 90 151 -278 O ATOM 1746 O CMET A 338 8.605 -47.516 13.069 0.41 10.00 O ANISOU 1746 O CMET A 338 644 1604 1553 198 -337 -784 O ATOM 1747 CB AMET A 338 8.467 -49.069 15.768 0.28 13.37 C ANISOU 1747 CB AMET A 338 1604 1542 1936 45 205 -284 C ATOM 1748 CB BMET A 338 8.632 -48.960 15.358 0.31 12.09 C ANISOU 1748 CB BMET A 338 1666 1521 1407 -115 -441 -422 C ATOM 1749 CB CMET A 338 8.607 -49.080 15.701 0.41 13.47 C ANISOU 1749 CB CMET A 338 1648 1392 2078 840 -139 -425 C ATOM 1750 CG AMET A 338 9.320 -50.321 15.824 0.28 13.99 C ANISOU 1750 CG AMET A 338 1877 1716 1723 -162 416 473 C ATOM 1751 CG BMET A 338 8.531 -49.237 16.764 0.31 11.22 C ANISOU 1751 CG BMET A 338 1726 1427 1112 -344 -1 44 C ATOM 1752 CG CMET A 338 9.516 -50.270 15.524 0.41 17.78 C ANISOU 1752 CG CMET A 338 2240 2148 2368 416 373 -318 C ATOM 1753 SD AMET A 338 10.042 -50.739 14.244 0.28 14.37 S ANISOU 1753 SD AMET A 338 2062 1661 1737 75 29 -17 S ATOM 1754 SD BMET A 338 10.101 -49.658 17.508 0.31 12.65 S ANISOU 1754 SD BMET A 338 2213 1351 1244 9 1 -111 S ATOM 1755 SD CMET A 338 10.891 -50.168 16.663 0.41 20.57 S ANISOU 1755 SD CMET A 338 2717 2837 2262 171 481 306 S ATOM 1756 CE AMET A 338 11.726 -50.806 14.839 0.28 17.31 C ANISOU 1756 CE AMET A 338 2508 2276 1795 -567 -226 718 C ATOM 1757 CE BMET A 338 10.329 -51.230 16.677 0.31 18.61 C ANISOU 1757 CE BMET A 338 2811 2473 1786 443 -362 -142 C ATOM 1758 CE CMET A 338 10.385 -48.850 17.723 0.41 25.08 C ANISOU 1758 CE CMET A 338 3193 3200 3135 -76 572 136 C ATOM 1759 H AMET A 338 7.488 -46.743 15.339 0.29 12.10 H ATOM 1760 H BMET A 338 7.424 -46.766 15.445 0.31 12.13 H ATOM 1761 H CMET A 338 7.453 -46.825 15.484 0.40 11.74 H ATOM 1762 HA AMET A 338 10.005 -47.657 15.928 0.29 12.67 H ATOM 1763 HA BMET A 338 10.006 -47.504 15.771 0.31 12.84 H ATOM 1764 HA CMET A 338 10.042 -47.579 15.875 0.40 12.69 H ATOM 1765 HB2AMET A 338 8.065 -48.958 16.643 0.29 16.06 H ATOM 1766 HB2BMET A 338 7.749 -49.003 14.961 0.31 14.53 H ATOM 1767 HB2CMET A 338 8.326 -49.068 16.629 0.40 16.18 H ATOM 1768 HB3AMET A 338 7.770 -49.228 15.113 0.29 16.06 H ATOM 1769 HB3BMET A 338 9.233 -49.602 14.950 0.31 14.53 H ATOM 1770 HB3CMET A 338 7.834 -49.220 15.132 0.40 16.18 H ATOM 1771 HG2AMET A 338 10.042 -50.183 16.457 0.29 16.80 H ATOM 1772 HG2BMET A 338 8.187 -48.451 17.217 0.31 13.48 H ATOM 1773 HG2CMET A 338 9.024 -51.085 15.708 0.40 21.35 H ATOM 1774 HG3AMET A 338 8.768 -51.066 16.108 0.29 16.80 H ATOM 1775 HG3BMET A 338 7.928 -49.985 16.896 0.31 13.48 H ATOM 1776 HG3CMET A 338 9.866 -50.280 14.619 0.40 21.35 H ATOM 1777 HE1AMET A 338 12.307 -51.028 14.107 0.29 20.79 H ATOM 1778 HE1BMET A 338 11.158 -51.618 16.967 0.31 22.34 H ATOM 1779 HE1CMET A 338 11.063 -48.706 18.387 0.40 30.11 H ATOM 1780 HE2AMET A 338 11.965 -49.948 15.198 0.29 20.79 H ATOM 1781 HE2BMET A 338 9.599 -51.810 16.902 0.31 22.34 H ATOM 1782 HE2CMET A 338 10.265 -48.056 17.198 0.40 30.11 H ATOM 1783 HE3AMET A 338 11.789 -51.477 15.523 0.29 20.79 H ATOM 1784 HE3BMET A 338 10.350 -51.081 15.729 0.31 22.34 H ATOM 1785 HE3CMET A 338 9.557 -49.091 18.146 0.40 30.11 H ATOM 1786 N CYS A 339 10.781 -47.420 13.517 1.00 10.01 N ANISOU 1786 N CYS A 339 869 1670 1265 109 -241 -525 N ATOM 1787 CA CYS A 339 11.266 -47.215 12.166 1.00 10.94 C ANISOU 1787 CA CYS A 339 963 1706 1487 202 -153 -629 C ATOM 1788 C CYS A 339 12.094 -48.420 11.707 1.00 10.64 C ANISOU 1788 C CYS A 339 634 1946 1465 -127 -295 -526 C ATOM 1789 O CYS A 339 13.024 -48.875 12.398 1.00 11.97 O ANISOU 1789 O CYS A 339 1127 2017 1403 152 -345 -684 O ATOM 1790 CB CYS A 339 12.138 -45.963 12.087 1.00 11.48 C ANISOU 1790 CB CYS A 339 1311 1773 1277 79 47 -220 C ATOM 1791 SG CYS A 339 11.214 -44.440 12.317 1.00 12.91 S ANISOU 1791 SG CYS A 339 1533 1774 1596 182 76 -383 S ATOM 1792 H ACYS A 339 11.413 -47.333 14.094 0.28 12.03 H ATOM 1793 H BCYS A 339 11.392 -47.632 14.085 0.31 12.03 H ATOM 1794 H CCYS A 339 11.423 -47.454 14.088 0.41 12.03 H ATOM 1795 HA CYS A 339 10.506 -47.107 11.556 1.00 13.14 H ATOM 1796 HB2 CYS A 339 12.816 -46.008 12.779 1.00 13.79 H ATOM 1797 HB3 CYS A 339 12.559 -45.928 11.214 1.00 13.79 H ATOM 1798 HG CYS A 339 12.057 -43.402 12.233 1.00 15.50 H ATOM 1799 N VAL A 340 11.808 -48.892 10.487 1.00 9.48 N ANISOU 1799 N VAL A 340 883 1565 1155 -63 -215 -423 N ATOM 1800 CA VAL A 340 12.640 -49.838 9.798 1.00 9.07 C ANISOU 1800 CA VAL A 340 913 1376 1157 -143 86 -402 C ATOM 1801 C VAL A 340 13.295 -49.058 8.657 1.00 8.63 C ANISOU 1801 C VAL A 340 904 1224 1150 -137 -176 -295 C ATOM 1802 O VAL A 340 12.630 -48.600 7.753 1.00 10.05 O ANISOU 1802 O VAL A 340 1036 1554 1227 -136 -91 -251 O ATOM 1803 CB VAL A 340 11.885 -51.091 9.241 1.00 10.96 C ANISOU 1803 CB VAL A 340 1388 1525 1253 -504 208 -243 C ATOM 1804 CG1 VAL A 340 12.882 -52.060 8.657 1.00 13.45 C ANISOU 1804 CG1 VAL A 340 1823 1597 1689 -421 153 -557 C ATOM 1805 CG2 VAL A 340 11.062 -51.730 10.314 1.00 13.53 C ANISOU 1805 CG2 VAL A 340 1585 1973 1581 -751 47 -285 C ATOM 1806 H VAL A 340 11.112 -48.661 10.038 1.00 11.39 H ATOM 1807 HA VAL A 340 13.346 -50.149 10.403 1.00 10.90 H ATOM 1808 HB VAL A 340 11.281 -50.808 8.524 1.00 13.17 H ATOM 1809 HG11 VAL A 340 12.412 -52.825 8.319 1.00 16.15 H ATOM 1810 HG12 VAL A 340 13.358 -51.626 7.946 1.00 16.15 H ATOM 1811 HG13 VAL A 340 13.495 -52.330 9.345 1.00 16.15 H ATOM 1812 HG21 VAL A 340 10.611 -52.494 9.948 1.00 16.25 H ATOM 1813 HG22 VAL A 340 11.641 -52.003 11.030 1.00 16.25 H ATOM 1814 HG23 VAL A 340 10.421 -51.093 10.637 1.00 16.25 H ATOM 1815 N ASN A 341 14.606 -48.902 8.759 1.00 8.92 N ANISOU 1815 N ASN A 341 1024 1181 1185 -81 -82 -221 N ATOM 1816 CA ASN A 341 15.378 -48.067 7.849 1.00 9.38 C ANISOU 1816 CA ASN A 341 1056 1213 1294 -64 22 -90 C ATOM 1817 C ASN A 341 16.190 -48.966 6.943 1.00 9.93 C ANISOU 1817 C ASN A 341 1207 1314 1254 167 17 -160 C ATOM 1818 O ASN A 341 16.869 -49.848 7.425 1.00 12.33 O ANISOU 1818 O ASN A 341 1654 1693 1338 552 63 -98 O ATOM 1819 CB ASN A 341 16.354 -47.197 8.660 1.00 9.60 C ANISOU 1819 CB ASN A 341 873 1339 1437 -189 44 -185 C ATOM 1820 CG ASN A 341 15.626 -46.399 9.763 1.00 10.28 C ANISOU 1820 CG ASN A 341 1096 1283 1526 -75 -200 -190 C ATOM 1821 OD1 ASN A 341 14.972 -45.374 9.479 1.00 11.20 O ANISOU 1821 OD1 ASN A 341 1487 1209 1560 23 -142 -178 O ATOM 1822 ND2 ASN A 341 15.723 -46.864 10.985 1.00 10.36 N ANISOU 1822 ND2 ASN A 341 1079 1319 1538 208 -102 -349 N ATOM 1823 H ASN A 341 15.085 -49.280 9.365 1.00 10.72 H ATOM 1824 HA ASN A 341 14.789 -47.497 7.313 1.00 11.27 H ATOM 1825 HB2 ASN A 341 17.014 -47.767 9.083 1.00 11.54 H ATOM 1826 HB3 ASN A 341 16.788 -46.566 8.065 1.00 11.54 H ATOM 1827 HD21 ASN A 341 15.280 -46.395 11.724 1.00 12.45 H ATOM 1828 HD22 ASN A 341 16.237 -47.679 11.161 1.00 12.45 H ATOM 1829 N TYR A 342 16.152 -48.760 5.639 1.00 10.10 N ANISOU 1829 N TYR A 342 1239 1178 1422 92 149 -169 N ATOM 1830 CA TYR A 342 16.917 -49.583 4.719 1.00 10.38 C ANISOU 1830 CA TYR A 342 1233 1275 1435 67 246 -122 C ATOM 1831 C TYR A 342 17.651 -48.693 3.735 1.00 10.45 C ANISOU 1831 C TYR A 342 1336 1193 1443 164 280 -266 C ATOM 1832 O TYR A 342 17.113 -47.742 3.175 1.00 11.24 O ANISOU 1832 O TYR A 342 1557 1299 1414 186 297 -92 O ATOM 1833 CB TYR A 342 16.047 -50.704 4.058 1.00 14.01 C ANISOU 1833 CB TYR A 342 1906 1637 1779 -95 174 -492 C ATOM 1834 CG TYR A 342 14.695 -50.349 3.562 1.00 14.26 C ANISOU 1834 CG TYR A 342 2378 1448 1592 -223 84 -314 C ATOM 1835 CD1 TYR A 342 13.631 -50.179 4.417 1.00 16.88 C ANISOU 1835 CD1 TYR A 342 2404 1688 2322 -239 289 -458 C ATOM 1836 CD2 TYR A 342 14.486 -50.102 2.195 1.00 16.70 C ANISOU 1836 CD2 TYR A 342 2448 1711 2186 -394 -116 -473 C ATOM 1837 CE1 TYR A 342 12.409 -49.779 4.008 1.00 20.90 C ANISOU 1837 CE1 TYR A 342 2444 1964 3533 -364 457 371 C ATOM 1838 CE2 TYR A 342 13.217 -49.721 1.736 1.00 18.91 C ANISOU 1838 CE2 TYR A 342 2378 2598 2210 -477 -495 -578 C ATOM 1839 CZ TYR A 342 12.179 -49.529 2.681 1.00 19.26 C ANISOU 1839 CZ TYR A 342 2058 2145 3116 -292 -8 -595 C ATOM 1840 OH TYR A 342 10.889 -49.196 2.219 1.00 24.79 O ANISOU 1840 OH TYR A 342 2639 2951 3831 -222 -151 -1380 O ATOM 1841 H TYR A 342 15.688 -48.145 5.258 1.00 12.14 H ATOM 1842 HA TYR A 342 17.607 -50.044 5.241 1.00 12.47 H ATOM 1843 HB2 TYR A 342 16.541 -51.053 3.299 1.00 16.82 H ATOM 1844 HB3 TYR A 342 15.930 -51.411 4.710 1.00 16.82 H ATOM 1845 HD1 TYR A 342 13.773 -50.305 5.327 1.00 20.27 H ATOM 1846 HD2 TYR A 342 15.188 -50.202 1.592 1.00 20.05 H ATOM 1847 HE1 TYR A 342 11.718 -49.691 4.624 1.00 25.10 H ATOM 1848 HE2 TYR A 342 13.069 -49.565 0.831 1.00 22.71 H ATOM 1849 HH TYR A 342 10.638 -49.749 1.668 1.00 29.77 H ATOM 1850 N AVAL A 343 18.942 -48.959 3.574 0.50 12.18 N ANISOU 1850 N AVAL A 343 1676 1230 1723 90 527 89 N ATOM 1851 N BVAL A 343 18.920 -49.008 3.544 0.50 12.59 N ANISOU 1851 N BVAL A 343 1748 1245 1791 269 645 -91 N ATOM 1852 CA AVAL A 343 19.742 -48.170 2.671 0.50 13.35 C ANISOU 1852 CA AVAL A 343 1609 1219 2246 -186 683 -110 C ATOM 1853 CA BVAL A 343 19.860 -48.155 2.862 0.50 14.32 C ANISOU 1853 CA BVAL A 343 1674 1464 2304 184 593 -96 C ATOM 1854 C AVAL A 343 19.552 -48.508 1.263 0.50 14.89 C ANISOU 1854 C AVAL A 343 2003 1171 2483 -435 1272 -220 C ATOM 1855 C BVAL A 343 19.929 -48.516 1.371 0.50 14.34 C ANISOU 1855 C BVAL A 343 1811 1324 2315 399 858 -166 C ATOM 1856 O AVAL A 343 19.248 -49.636 0.856 0.50 16.69 O ANISOU 1856 O AVAL A 343 2920 1016 2406 -313 1413 -226 O ATOM 1857 O BVAL A 343 20.058 -49.714 1.041 0.50 13.57 O ANISOU 1857 O BVAL A 343 1713 1633 1811 135 847 -90 O ATOM 1858 CB AVAL A 343 21.237 -48.194 2.967 0.50 17.41 C ANISOU 1858 CB AVAL A 343 1908 1901 2805 228 729 582 C ATOM 1859 CB BVAL A 343 21.229 -48.234 3.623 0.50 16.46 C ANISOU 1859 CB BVAL A 343 1830 2205 2218 -104 303 -134 C ATOM 1860 CG1AVAL A 343 21.460 -47.808 4.393 0.50 17.77 C ANISOU 1860 CG1AVAL A 343 1926 2381 2442 335 -257 140 C ATOM 1861 CG1BVAL A 343 22.334 -47.564 2.853 0.50 17.96 C ANISOU 1861 CG1BVAL A 343 1987 2291 2546 -413 -52 257 C ATOM 1862 CG2AVAL A 343 21.867 -49.548 2.672 0.50 18.57 C ANISOU 1862 CG2AVAL A 343 2203 1872 2983 383 740 1062 C ATOM 1863 CG2BVAL A 343 21.128 -47.575 5.014 0.50 17.63 C ANISOU 1863 CG2BVAL A 343 2008 2131 2559 -128 -335 -151 C ATOM 1864 H AVAL A 343 19.369 -49.588 3.975 0.50 14.64 H ATOM 1865 H BVAL A 343 19.269 -49.746 3.815 0.50 15.12 H ATOM 1866 HA AVAL A 343 19.457 -47.238 2.772 0.50 16.04 H ATOM 1867 HA BVAL A 343 19.543 -47.230 2.924 0.50 17.20 H ATOM 1868 HB AVAL A 343 21.681 -47.527 2.403 0.50 20.90 H ATOM 1869 HB BVAL A 343 21.472 -49.175 3.749 0.50 19.76 H ATOM 1870 HG11AVAL A 343 22.403 -47.825 4.577 0.50 21.33 H ATOM 1871 HG11BVAL A 343 23.151 -47.635 3.353 0.50 21.57 H ATOM 1872 HG12AVAL A 343 21.114 -46.924 4.536 0.50 21.33 H ATOM 1873 HG12BVAL A 343 22.431 -48.000 2.004 0.50 21.57 H ATOM 1874 HG13AVAL A 343 21.005 -48.434 4.961 0.50 21.33 H ATOM 1875 HG13BVAL A 343 22.109 -46.640 2.724 0.50 21.57 H ATOM 1876 HG21AVAL A 343 22.804 -49.506 2.876 0.50 22.30 H ATOM 1877 HG21BVAL A 343 21.980 -47.641 5.453 0.50 21.17 H ATOM 1878 HG22AVAL A 343 21.442 -50.215 3.216 0.50 22.30 H ATOM 1879 HG22BVAL A 343 20.885 -46.653 4.906 0.50 21.17 H ATOM 1880 HG23AVAL A 343 21.742 -49.754 1.743 0.50 22.30 H ATOM 1881 HG23BVAL A 343 20.459 -48.033 5.529 0.50 21.17 H ATOM 1882 N LEU A 344 19.807 -47.495 0.485 1.00 15.69 N ANISOU 1882 N LEU A 344 2275 1494 2191 -219 1093 -277 N ATOM 1883 CA LEU A 344 19.662 -47.571 -0.965 1.00 16.82 C ANISOU 1883 CA LEU A 344 2756 1825 1810 -441 992 -548 C ATOM 1884 C LEU A 344 20.925 -47.195 -1.718 1.00 18.32 C ANISOU 1884 C LEU A 344 3175 1887 1901 -336 1133 -614 C ATOM 1885 O LEU A 344 20.951 -47.304 -2.925 1.00 22.59 O ANISOU 1885 O LEU A 344 3363 2798 2422 -330 1267 -513 O ATOM 1886 CB LEU A 344 18.525 -46.597 -1.429 1.00 17.30 C ANISOU 1886 CB LEU A 344 2615 2206 1754 -604 458 -272 C ATOM 1887 CG LEU A 344 17.134 -46.719 -0.787 1.00 19.28 C ANISOU 1887 CG LEU A 344 2661 2667 1997 -844 432 -138 C ATOM 1888 CD1 LEU A 344 16.273 -45.510 -1.077 1.00 19.32 C ANISOU 1888 CD1 LEU A 344 2630 2782 1928 -690 354 -266 C ATOM 1889 CD2 LEU A 344 16.434 -47.963 -1.115 1.00 23.20 C ANISOU 1889 CD2 LEU A 344 3144 2987 2685 -914 -169 -45 C ATOM 1890 H ALEU A 344 20.073 -46.727 0.766 0.50 18.84 H ATOM 1891 H BLEU A 344 19.808 -46.677 0.748 0.50 18.84 H ATOM 1892 HA LEU A 344 19.410 -48.484 -1.219 1.00 20.20 H ATOM 1893 HB2 LEU A 344 18.829 -45.690 -1.266 1.00 20.78 H ATOM 1894 HB3 LEU A 344 18.403 -46.720 -2.384 1.00 20.78 H ATOM 1895 HG LEU A 344 17.265 -46.731 0.174 1.00 23.15 H ATOM 1896 HD11 LEU A 344 15.417 -45.629 -0.659 1.00 23.20 H ATOM 1897 HD12 LEU A 344 16.705 -44.728 -0.725 1.00 23.20 H ATOM 1898 HD13 LEU A 344 16.165 -45.425 -2.027 1.00 23.20 H ATOM 1899 HD21 LEU A 344 15.578 -47.964 -0.680 1.00 27.86 H ATOM 1900 HD22 LEU A 344 16.317 -48.014 -2.067 1.00 27.86 H ATOM 1901 HD23 LEU A 344 16.958 -48.707 -0.809 1.00 27.86 H ATOM 1902 N SER A 345 21.964 -46.750 -1.010 1.00 17.27 N ANISOU 1902 N SER A 345 2722 1593 2248 -418 1182 -366 N ATOM 1903 CA SER A 345 23.223 -46.372 -1.648 1.00 17.01 C ANISOU 1903 CA SER A 345 2432 1872 2159 -346 982 -61 C ATOM 1904 C SER A 345 24.381 -46.475 -0.660 1.00 17.89 C ANISOU 1904 C SER A 345 2297 1853 2647 -276 1280 -468 C ATOM 1905 O SER A 345 24.227 -46.649 0.536 1.00 20.04 O ANISOU 1905 O SER A 345 2304 2267 3042 101 1072 161 O ATOM 1906 CB SER A 345 23.163 -44.891 -2.156 1.00 18.10 C ANISOU 1906 CB SER A 345 2463 1864 2549 -192 1374 -445 C ATOM 1907 OG SER A 345 23.315 -43.961 -1.081 1.00 18.41 O ANISOU 1907 OG SER A 345 2754 1728 2512 154 1176 -400 O ATOM 1908 H SER A 345 21.964 -46.658 -0.155 1.00 20.74 H ATOM 1909 HA SER A 345 23.402 -46.962 -2.409 1.00 20.43 H ATOM 1910 HB2 SER A 345 23.877 -44.749 -2.796 1.00 21.73 H ATOM 1911 HB3 SER A 345 22.304 -44.740 -2.581 1.00 21.73 H ATOM 1912 HG SER A 345 23.409 -44.364 -0.373 1.00 22.11 H ATOM 1913 N GLU A 346 25.594 -46.400 -1.224 1.00 19.74 N ANISOU 1913 N GLU A 346 2491 1918 3090 15 1234 -211 N ATOM 1914 CA GLU A 346 26.793 -46.122 -0.435 1.00 19.45 C ANISOU 1914 CA GLU A 346 2132 2170 3090 -24 845 -438 C ATOM 1915 C GLU A 346 26.765 -44.661 0.015 1.00 18.39 C ANISOU 1915 C GLU A 346 2163 1934 2891 -226 773 -171 C ATOM 1916 O GLU A 346 25.953 -43.872 -0.471 1.00 20.91 O ANISOU 1916 O GLU A 346 2424 2081 3440 -15 919 12 O ATOM 1917 CB GLU A 346 28.008 -46.409 -1.320 1.00 22.91 C ANISOU 1917 CB GLU A 346 2542 2707 3455 254 1270 -687 C ATOM 1918 CG GLU A 346 27.967 -47.758 -2.021 1.00 26.15 C ANISOU 1918 CG GLU A 346 3041 3370 3523 463 1184 -627 C ATOM 1919 CD GLU A 346 28.358 -48.901 -1.135 1.00 32.35 C ANISOU 1919 CD GLU A 346 3993 4084 4214 93 85 -694 C ATOM 1920 OE1 GLU A 346 28.821 -48.608 -0.026 1.00 34.81 O ANISOU 1920 OE1 GLU A 346 4563 4186 4476 371 194 -867 O ATOM 1921 OE2 GLU A 346 28.238 -50.101 -1.571 1.00 36.63 O ANISOU 1921 OE2 GLU A 346 4373 4424 5123 -83 245 -1222 O ATOM 1922 H GLU A 346 25.745 -46.507 -2.063 1.00 23.70 H ATOM 1923 HA GLU A 346 26.822 -46.703 0.354 1.00 23.36 H ATOM 1924 HB2 GLU A 346 28.064 -45.723 -2.004 1.00 27.50 H ATOM 1925 HB3 GLU A 346 28.806 -46.387 -0.769 1.00 27.50 H ATOM 1926 HG2 GLU A 346 27.064 -47.921 -2.336 1.00 31.39 H ATOM 1927 HG3 GLU A 346 28.580 -47.741 -2.773 1.00 31.39 H ATOM 1928 N ILE A 347 27.691 -44.318 0.898 1.00 19.32 N ANISOU 1928 N ILE A 347 2324 2068 2948 -71 1105 -196 N ATOM 1929 CA ILE A 347 27.905 -42.933 1.257 1.00 19.39 C ANISOU 1929 CA ILE A 347 2178 2011 3180 -315 963 -73 C ATOM 1930 C ILE A 347 28.391 -42.174 0.010 1.00 20.96 C ANISOU 1930 C ILE A 347 2086 2210 3668 -10 1316 59 C ATOM 1931 O ILE A 347 29.294 -42.644 -0.693 1.00 25.19 O ANISOU 1931 O ILE A 347 2881 2739 3949 -149 1660 -124 O ATOM 1932 CB ILE A 347 28.845 -42.803 2.474 1.00 20.78 C ANISOU 1932 CB ILE A 347 2481 2219 3197 -91 866 -65 C ATOM 1933 CG1 ILE A 347 28.262 -43.474 3.729 1.00 20.92 C ANISOU 1933 CG1 ILE A 347 2674 2311 2965 15 888 -364 C ATOM 1934 CG2 ILE A 347 29.139 -41.319 2.726 1.00 24.25 C ANISOU 1934 CG2 ILE A 347 2935 2588 3692 -341 632 54 C ATOM 1935 CD1 ILE A 347 29.247 -43.628 4.889 1.00 25.72 C ANISOU 1935 CD1 ILE A 347 3203 3044 3528 -158 828 -133 C ATOM 1936 H ILE A 347 28.208 -44.873 1.304 1.00 23.19 H ATOM 1937 HA ILE A 347 27.043 -42.546 1.515 1.00 23.29 H ATOM 1938 HB ILE A 347 29.682 -43.244 2.258 1.00 24.95 H ATOM 1939 HG12 ILE A 347 27.516 -42.942 4.046 1.00 25.12 H ATOM 1940 HG13 ILE A 347 27.951 -44.361 3.488 1.00 25.12 H ATOM 1941 HG21 ILE A 347 29.723 -41.241 3.483 1.00 29.12 H ATOM 1942 HG22 ILE A 347 29.560 -40.948 1.947 1.00 29.12 H ATOM 1943 HG23 ILE A 347 28.313 -40.863 2.901 1.00 29.12 H ATOM 1944 HD11 ILE A 347 28.800 -44.054 5.624 1.00 30.88 H ATOM 1945 HD12 ILE A 347 29.988 -44.166 4.600 1.00 30.88 H ATOM 1946 HD13 ILE A 347 29.556 -42.758 5.153 1.00 30.88 H ATOM 1947 N GLU A 348 27.746 -41.059 -0.244 1.00 20.73 N ANISOU 1947 N GLU A 348 2638 2310 2927 -341 1346 -144 N ATOM 1948 CA GLU A 348 28.032 -40.185 -1.357 1.00 21.41 C ANISOU 1948 CA GLU A 348 2875 2445 2814 -487 1122 -2 C ATOM 1949 C GLU A 348 28.398 -38.838 -0.816 1.00 24.84 C ANISOU 1949 C GLU A 348 2997 2954 3487 -700 1492 143 C ATOM 1950 O GLU A 348 27.764 -38.276 0.076 1.00 22.95 O ANISOU 1950 O GLU A 348 3148 2602 2969 -854 1178 233 O ATOM 1951 CB GLU A 348 26.791 -40.066 -2.241 1.00 23.57 C ANISOU 1951 CB GLU A 348 3417 2465 3071 -702 395 259 C ATOM 1952 CG GLU A 348 26.415 -41.444 -2.835 1.00 27.88 C ANISOU 1952 CG GLU A 348 3770 3219 3603 -1139 443 338 C ATOM 1953 CD GLU A 348 25.170 -41.406 -3.716 1.00 33.87 C ANISOU 1953 CD GLU A 348 4568 4121 4179 -520 344 8 C ATOM 1954 OE1 GLU A 348 24.542 -40.316 -3.776 1.00 38.01 O ANISOU 1954 OE1 GLU A 348 4653 4770 5020 -415 881 81 O ATOM 1955 OE2 GLU A 348 24.846 -42.472 -4.342 1.00 37.04 O ANISOU 1955 OE2 GLU A 348 5169 4442 4464 -916 -20 -334 O ATOM 1956 H GLU A 348 27.100 -40.772 0.245 1.00 24.89 H ATOM 1957 HA GLU A 348 28.778 -40.537 -1.886 1.00 25.70 H ATOM 1958 HB2 GLU A 348 26.045 -39.747 -1.710 1.00 28.29 H ATOM 1959 HB3 GLU A 348 26.973 -39.456 -2.972 1.00 28.29 H ATOM 1960 HG2 GLU A 348 27.153 -41.765 -3.377 1.00 33.47 H ATOM 1961 HG3 GLU A 348 26.246 -42.064 -2.109 1.00 33.47 H ATOM 1962 N LYS A 349 29.446 -38.250 -1.387 1.00 29.94 N ANISOU 1962 N LYS A 349 3700 3626 4049 -1377 999 44 N ATOM 1963 CA LYS A 349 29.929 -36.934 -0.903 1.00 33.62 C ANISOU 1963 CA LYS A 349 4225 4351 4199 -679 227 154 C ATOM 1964 C LYS A 349 30.438 -36.099 -2.055 1.00 39.23 C ANISOU 1964 C LYS A 349 5037 4929 4939 -287 431 36 C ATOM 1965 O LYS A 349 30.754 -36.639 -3.133 1.00 41.46 O ANISOU 1965 O LYS A 349 5333 5351 5068 -272 1119 -184 O ATOM 1966 CB LYS A 349 31.031 -37.118 0.145 1.00 36.36 C ANISOU 1966 CB LYS A 349 4509 4671 4634 -319 -53 -61 C ATOM 1967 CG LYS A 349 31.535 -35.800 0.789 1.00 36.93 C ANISOU 1967 CG LYS A 349 4572 4758 4701 36 83 171 C ATOM 1968 CD LYS A 349 32.278 -36.077 2.133 1.00 36.37 C ANISOU 1968 CD LYS A 349 4499 4799 4522 173 159 -117 C ATOM 1969 CE LYS A 349 33.415 -37.094 1.974 1.00 36.60 C ANISOU 1969 CE LYS A 349 4542 4795 4567 351 -541 -56 C ATOM 1970 NZ LYS A 349 34.205 -37.344 3.250 1.00 38.28 N ANISOU 1970 NZ LYS A 349 4755 4993 4796 444 -319 102 N ATOM 1971 H LYS A 349 29.894 -38.575 -2.045 1.00 35.94 H ATOM 1972 HA LYS A 349 29.185 -36.454 -0.483 1.00 40.36 H ATOM 1973 HB2 LYS A 349 30.691 -37.681 0.858 1.00 43.64 H ATOM 1974 HB3 LYS A 349 31.792 -37.548 -0.276 1.00 43.64 H ATOM 1975 HG2 LYS A 349 32.153 -35.362 0.183 1.00 44.33 H ATOM 1976 HG3 LYS A 349 30.778 -35.222 0.973 1.00 44.33 H ATOM 1977 HD2 LYS A 349 32.660 -35.248 2.461 1.00 43.66 H ATOM 1978 HD3 LYS A 349 31.646 -36.431 2.778 1.00 43.66 H ATOM 1979 HE2 LYS A 349 33.037 -37.941 1.689 1.00 43.93 H ATOM 1980 HE3 LYS A 349 34.033 -36.768 1.302 1.00 43.93 H ATOM 1981 HZ1 LYS A 349 34.898 -37.988 3.086 1.00 45.95 H ATOM 1982 HZ2 LYS A 349 34.604 -36.526 3.554 1.00 45.95 H ATOM 1983 HZ3 LYS A 349 33.623 -37.682 3.935 1.00 45.95 H TER 1984 LYS A 349 ATOM 1985 N VAL B 357 7.681 -37.268 32.262 1.00 40.39 N ANISOU 1985 N VAL B 357 5200 5285 4862 194 -106 -349 N ATOM 1986 CA VAL B 357 6.725 -38.364 32.465 1.00 40.06 C ANISOU 1986 CA VAL B 357 5183 5098 4941 35 -141 -174 C ATOM 1987 C VAL B 357 7.458 -39.697 32.715 1.00 32.38 C ANISOU 1987 C VAL B 357 4596 4015 3690 -305 -73 382 C ATOM 1988 O VAL B 357 8.681 -39.794 32.421 1.00 35.91 O ANISOU 1988 O VAL B 357 5286 3680 4676 48 281 -8 O ATOM 1989 CB VAL B 357 5.825 -38.557 31.234 1.00 44.75 C ANISOU 1989 CB VAL B 357 5618 5662 5725 53 -59 20 C ATOM 1990 CG1 VAL B 357 6.662 -39.057 30.030 1.00 45.95 C ANISOU 1990 CG1 VAL B 357 5859 5898 5704 7 -65 52 C ATOM 1991 CG2 VAL B 357 4.649 -39.527 31.563 1.00 48.10 C ANISOU 1991 CG2 VAL B 357 6076 6040 6158 126 -54 14 C ATOM 1992 HA VAL B 357 6.158 -38.168 33.240 1.00 48.09 H ATOM 1993 HB VAL B 357 5.438 -37.691 30.988 1.00 53.72 H ATOM 1994 HG11 VAL B 357 6.083 -39.172 29.273 1.00 55.16 H ATOM 1995 HG12 VAL B 357 7.339 -38.407 29.830 1.00 55.16 H ATOM 1996 HG13 VAL B 357 7.070 -39.895 30.260 1.00 55.16 H ATOM 1997 HG21 VAL B 357 4.102 -39.633 30.781 1.00 57.73 H ATOM 1998 HG22 VAL B 357 5.009 -40.378 31.827 1.00 57.73 H ATOM 1999 HG23 VAL B 357 4.129 -39.155 32.279 1.00 57.73 H ATOM 2000 N CYS B 358 6.755 -40.691 33.293 1.00 29.50 N ANISOU 2000 N CYS B 358 4247 3759 3203 -698 -402 1670 N ATOM 2001 CA CYS B 358 7.414 -41.984 33.556 1.00 24.15 C ANISOU 2001 CA CYS B 358 3670 2961 2545 -436 623 808 C ATOM 2002 C CYS B 358 7.470 -42.795 32.284 1.00 22.87 C ANISOU 2002 C CYS B 358 3759 2243 2687 -40 252 155 C ATOM 2003 O CYS B 358 6.459 -43.161 31.764 1.00 22.32 O ANISOU 2003 O CYS B 358 3784 2540 2157 -145 216 461 O ATOM 2004 CB CYS B 358 6.774 -42.848 34.665 1.00 27.85 C ANISOU 2004 CB CYS B 358 4252 3496 2834 127 33 1637 C ATOM 2005 SG CYS B 358 7.795 -44.272 35.008 1.00 32.96 S ANISOU 2005 SG CYS B 358 6287 3459 2779 337 61 -119 S ATOM 2006 H CYS B 358 5.930 -40.644 33.533 1.00 35.42 H ATOM 2007 HA CYS B 358 8.338 -41.806 33.828 1.00 29.00 H ATOM 2008 HB2 CYS B 358 6.694 -42.325 35.478 1.00 33.43 H ATOM 2009 HB3 CYS B 358 5.903 -43.158 34.373 1.00 33.43 H ATOM 2010 HG CYS B 358 7.217 -45.002 35.971 1.00 39.57 H ATOM 2011 N GLN B 359 8.667 -43.013 31.780 1.00 25.76 N ANISOU 2011 N GLN B 359 4060 2074 3652 512 1292 619 N ATOM 2012 CA GLN B 359 8.828 -43.777 30.571 1.00 23.96 C ANISOU 2012 CA GLN B 359 3712 2264 3127 244 1270 273 C ATOM 2013 C GLN B 359 8.470 -45.247 30.814 1.00 20.60 C ANISOU 2013 C GLN B 359 3771 1687 2371 116 921 483 C ATOM 2014 O GLN B 359 8.986 -45.886 31.747 1.00 23.11 O ANISOU 2014 O GLN B 359 4020 1815 2944 415 732 115 O ATOM 2015 CB GLN B 359 10.280 -43.705 30.100 1.00 31.20 C ANISOU 2015 CB GLN B 359 4101 3604 4151 454 865 -290 C ATOM 2016 CG GLN B 359 10.567 -42.441 29.220 1.00 36.36 C ANISOU 2016 CG GLN B 359 4622 4415 4777 433 390 -252 C ATOM 2017 CD GLN B 359 9.578 -42.366 28.044 1.00 39.15 C ANISOU 2017 CD GLN B 359 5140 4804 4930 96 284 -315 C ATOM 2018 OE1 GLN B 359 8.651 -41.510 28.009 1.00 42.12 O ANISOU 2018 OE1 GLN B 359 5394 5160 5448 55 464 -587 O ATOM 2019 NE2 GLN B 359 9.730 -43.306 27.100 1.00 41.92 N ANISOU 2019 NE2 GLN B 359 5540 5327 5060 96 72 27 N ATOM 2020 H GLN B 359 9.403 -42.727 32.121 1.00 30.92 H ATOM 2021 HA GLN B 359 8.246 -43.418 29.868 1.00 28.76 H ATOM 2022 HB2 GLN B 359 10.863 -43.669 30.874 1.00 37.46 H ATOM 2023 HB3 GLN B 359 10.481 -44.490 29.569 1.00 37.46 H ATOM 2024 HG2 GLN B 359 10.465 -41.642 29.760 1.00 43.64 H ATOM 2025 HG3 GLN B 359 11.467 -42.495 28.862 1.00 43.64 H ATOM 2026 HE21 GLN B 359 9.208 -43.319 26.417 1.00 50.32 H ATOM 2027 HE22 GLN B 359 10.349 -43.898 27.179 1.00 50.32 H ATOM 2028 N PRO B 360 7.565 -45.790 30.002 1.00 23.83 N ANISOU 2028 N PRO B 360 4127 1956 2970 -86 889 426 N ATOM 2029 CA PRO B 360 7.259 -47.240 30.088 1.00 21.97 C ANISOU 2029 CA PRO B 360 3571 1925 2851 54 829 269 C ATOM 2030 C PRO B 360 8.522 -48.060 29.832 1.00 20.59 C ANISOU 2030 C PRO B 360 3732 1711 2380 343 1748 313 C ATOM 2031 O PRO B 360 9.415 -47.697 29.079 1.00 26.26 O ANISOU 2031 O PRO B 360 4686 1777 3513 85 2238 182 O ATOM 2032 CB PRO B 360 6.221 -47.443 28.958 1.00 26.63 C ANISOU 2032 CB PRO B 360 3942 2328 3846 -947 332 451 C ATOM 2033 CG PRO B 360 5.643 -45.974 28.682 1.00 34.20 C ANISOU 2033 CG PRO B 360 4516 3852 4627 -749 465 172 C ATOM 2034 CD PRO B 360 6.850 -45.129 28.897 1.00 32.00 C ANISOU 2034 CD PRO B 360 4433 3557 4168 -500 367 446 C ATOM 2035 HA PRO B 360 6.869 -47.471 30.956 1.00 26.38 H ATOM 2036 HB2 PRO B 360 6.659 -47.797 28.167 1.00 31.97 H ATOM 2037 HB3 PRO B 360 5.518 -48.040 29.260 1.00 31.97 H ATOM 2038 HG2 PRO B 360 5.322 -45.903 27.769 1.00 41.06 H ATOM 2039 HG3 PRO B 360 4.945 -45.761 29.321 1.00 41.06 H ATOM 2040 HD2 PRO B 360 7.401 -45.122 28.098 1.00 38.41 H ATOM 2041 HD3 PRO B 360 6.590 -44.232 29.155 1.00 38.41 H ATOM 2042 N THR B 361 8.589 -49.189 30.500 1.00 16.82 N ANISOU 2042 N THR B 361 2943 1679 1767 636 1108 833 N ATOM 2043 CA THR B 361 9.676 -50.111 30.281 1.00 15.17 C ANISOU 2043 CA THR B 361 2386 1732 1644 787 475 795 C ATOM 2044 C THR B 361 9.351 -51.017 29.107 1.00 13.81 C ANISOU 2044 C THR B 361 2196 1296 1754 526 593 430 C ATOM 2045 O THR B 361 8.328 -51.708 29.119 1.00 14.94 O ANISOU 2045 O THR B 361 2197 1663 1817 760 657 733 O ATOM 2046 CB THR B 361 9.928 -50.833 31.559 1.00 18.99 C ANISOU 2046 CB THR B 361 3273 2175 1767 505 29 651 C ATOM 2047 OG1 THR B 361 10.114 -49.835 32.611 1.00 23.31 O ANISOU 2047 OG1 THR B 361 3675 2786 2396 388 -151 687 O ATOM 2048 CG2 THR B 361 11.176 -51.631 31.429 1.00 23.14 C ANISOU 2048 CG2 THR B 361 3390 2619 2781 125 163 950 C ATOM 2049 H THR B 361 8.017 -49.446 31.089 1.00 20.19 H ATOM 2050 HA THR B 361 10.484 -49.603 30.056 1.00 18.21 H ATOM 2051 HB THR B 361 9.186 -51.420 31.772 1.00 22.80 H ATOM 2052 HG1 THR B 361 10.255 -50.206 33.328 1.00 27.99 H ATOM 2053 HG21 THR B 361 11.351 -52.102 32.247 1.00 27.78 H ATOM 2054 HG22 THR B 361 11.087 -52.265 30.716 1.00 27.78 H ATOM 2055 HG23 THR B 361 11.917 -51.050 31.240 1.00 27.78 H ATOM 2056 N ARG B 362 10.227 -51.007 28.106 1.00 12.00 N ANISOU 2056 N ARG B 362 1632 1374 1553 507 302 446 N ATOM 2057 CA ARG B 362 10.009 -51.750 26.850 1.00 12.22 C ANISOU 2057 CA ARG B 362 1564 1484 1596 279 387 303 C ATOM 2058 C ARG B 362 11.245 -52.134 26.143 1.00 11.09 C ANISOU 2058 C ARG B 362 1124 1468 1622 392 431 314 C ATOM 2059 O ARG B 362 12.306 -51.547 26.327 1.00 13.10 O ANISOU 2059 O ARG B 362 1544 1618 1814 481 425 686 O ATOM 2060 CB ARG B 362 9.117 -50.983 25.935 1.00 14.52 C ANISOU 2060 CB ARG B 362 2024 1646 1845 216 688 185 C ATOM 2061 CG ARG B 362 9.736 -49.746 25.444 1.00 17.47 C ANISOU 2061 CG ARG B 362 2213 1843 2582 144 355 -43 C ATOM 2062 CD ARG B 362 8.885 -49.064 24.358 1.00 23.17 C ANISOU 2062 CD ARG B 362 3140 2520 3145 174 336 -882 C ATOM 2063 NE ARG B 362 9.499 -47.793 23.988 1.00 22.84 N ANISOU 2063 NE ARG B 362 3345 2772 2564 403 412 -1027 N ATOM 2064 CZ ARG B 362 9.065 -46.605 24.363 1.00 24.43 C ANISOU 2064 CZ ARG B 362 3810 2783 2689 603 737 -343 C ATOM 2065 NH1 ARG B 362 9.718 -45.533 23.920 1.00 22.63 N ANISOU 2065 NH1 ARG B 362 3550 2822 2228 962 283 -345 N ATOM 2066 NH2 ARG B 362 7.958 -46.473 25.074 1.00 25.73 N ANISOU 2066 NH2 ARG B 362 3835 2846 3094 602 996 -186 N ATOM 2067 H ARG B 362 10.968 -50.572 28.123 1.00 14.42 H ATOM 2068 HA ARG B 362 9.541 -52.582 27.073 1.00 14.68 H ATOM 2069 HB2 ARG B 362 8.901 -51.537 25.167 1.00 17.43 H ATOM 2070 HB3 ARG B 362 8.306 -50.745 26.410 1.00 17.43 H ATOM 2071 HG2 ARG B 362 9.837 -49.127 26.183 1.00 20.98 H ATOM 2072 HG3 ARG B 362 10.603 -49.954 25.062 1.00 20.98 H ATOM 2073 HD2 ARG B 362 8.845 -49.630 23.571 1.00 27.82 H ATOM 2074 HD3 ARG B 362 7.994 -48.892 24.701 1.00 27.82 H ATOM 2075 HE ARG B 362 10.287 -47.824 23.423 1.00 27.43 H ATOM 2076 HH11 ARG B 362 10.431 -45.629 23.448 1.00 27.18 H ATOM 2077 HH12 ARG B 362 9.452 -44.745 24.141 1.00 27.18 H ATOM 2078 HH21 ARG B 362 7.534 -47.172 25.343 1.00 30.89 H ATOM 2079 HH22 ARG B 362 7.683 -45.691 25.300 1.00 30.89 H ATOM 2080 N PHE B 363 11.139 -53.127 25.283 1.00 10.40 N ANISOU 2080 N PHE B 363 1444 1401 1107 362 327 371 N ATOM 2081 CA PHE B 363 12.245 -53.475 24.426 1.00 10.02 C ANISOU 2081 CA PHE B 363 1474 1189 1143 328 418 289 C ATOM 2082 C PHE B 363 11.702 -53.965 23.106 1.00 9.23 C ANISOU 2082 C PHE B 363 1299 1066 1141 200 402 73 C ATOM 2083 O PHE B 363 10.570 -54.467 23.015 1.00 9.37 O ANISOU 2083 O PHE B 363 1101 1268 1190 216 246 105 O ATOM 2084 CB PHE B 363 13.167 -54.562 25.063 1.00 11.00 C ANISOU 2084 CB PHE B 363 1494 1305 1382 355 218 311 C ATOM 2085 CG PHE B 363 12.542 -55.922 25.183 1.00 10.58 C ANISOU 2085 CG PHE B 363 1320 1367 1332 131 131 -2 C ATOM 2086 CD1 PHE B 363 11.700 -56.210 26.252 1.00 11.66 C ANISOU 2086 CD1 PHE B 363 1546 1571 1313 181 220 -51 C ATOM 2087 CD2 PHE B 363 12.847 -56.922 24.275 1.00 11.77 C ANISOU 2087 CD2 PHE B 363 1643 1329 1500 318 31 94 C ATOM 2088 CE1 PHE B 363 11.126 -57.505 26.362 1.00 12.85 C ANISOU 2088 CE1 PHE B 363 1475 1696 1712 199 100 -406 C ATOM 2089 CE2 PHE B 363 12.330 -58.204 24.437 1.00 12.44 C ANISOU 2089 CE2 PHE B 363 2008 1400 1321 226 -162 -85 C ATOM 2090 CZ PHE B 363 11.480 -58.494 25.448 1.00 13.11 C ANISOU 2090 CZ PHE B 363 1694 1563 1724 203 -361 -376 C ATOM 2091 H PHE B 363 10.437 -53.614 25.178 1.00 12.50 H ATOM 2092 HA PHE B 363 12.786 -52.676 24.258 1.00 12.03 H ATOM 2093 HB2 PHE B 363 13.963 -54.651 24.516 1.00 13.22 H ATOM 2094 HB3 PHE B 363 13.415 -54.272 25.955 1.00 13.22 H ATOM 2095 HD1 PHE B 363 11.476 -55.544 26.863 1.00 14.00 H ATOM 2096 HD2 PHE B 363 13.445 -56.752 23.584 1.00 14.14 H ATOM 2097 HE1 PHE B 363 10.557 -57.705 27.070 1.00 15.44 H ATOM 2098 HE2 PHE B 363 12.532 -58.860 23.809 1.00 14.95 H ATOM 2099 HZ PHE B 363 11.111 -59.346 25.517 1.00 15.75 H ATOM 2100 N ILE B 364 12.544 -53.889 22.082 1.00 9.45 N ANISOU 2100 N ILE B 364 1393 1055 1145 238 306 86 N ATOM 2101 CA ILE B 364 12.187 -54.367 20.757 1.00 9.87 C ANISOU 2101 CA ILE B 364 1669 1134 947 268 262 47 C ATOM 2102 C ILE B 364 12.750 -55.775 20.519 1.00 8.42 C ANISOU 2102 C ILE B 364 1147 1108 943 171 229 -56 C ATOM 2103 O ILE B 364 13.843 -56.106 20.977 1.00 9.60 O ANISOU 2103 O ILE B 364 1256 1186 1204 219 107 118 O ATOM 2104 CB ILE B 364 12.759 -53.379 19.714 1.00 13.14 C ANISOU 2104 CB ILE B 364 2371 1352 1270 37 445 138 C ATOM 2105 CG1 ILE B 364 12.090 -52.042 19.842 1.00 15.07 C ANISOU 2105 CG1 ILE B 364 2644 1487 1596 261 194 -12 C ATOM 2106 CG2 ILE B 364 12.749 -53.941 18.278 1.00 14.62 C ANISOU 2106 CG2 ILE B 364 2266 1600 1690 262 265 -187 C ATOM 2107 CD1 ILE B 364 12.913 -50.927 19.208 1.00 18.43 C ANISOU 2107 CD1 ILE B 364 3130 1665 2207 505 854 -228 C ATOM 2108 H ILE B 364 13.338 -53.561 22.133 1.00 11.36 H ATOM 2109 HA ILE B 364 11.212 -54.395 20.665 1.00 11.86 H ATOM 2110 HB ILE B 364 13.691 -53.243 19.947 1.00 15.78 H ATOM 2111 HG12 ILE B 364 11.229 -52.073 19.396 1.00 18.10 H ATOM 2112 HG13 ILE B 364 11.972 -51.834 20.782 1.00 18.10 H ATOM 2113 HG21 ILE B 364 13.115 -53.283 17.683 1.00 17.56 H ATOM 2114 HG22 ILE B 364 13.282 -54.739 18.251 1.00 17.56 H ATOM 2115 HG23 ILE B 364 11.845 -54.142 18.028 1.00 17.56 H ATOM 2116 HD11 ILE B 364 12.446 -50.095 19.315 1.00 22.13 H ATOM 2117 HD12 ILE B 364 13.767 -50.881 19.645 1.00 22.13 H ATOM 2118 HD13 ILE B 364 13.032 -51.119 18.275 1.00 22.13 H ATOM 2119 N SER B 365 12.028 -56.540 19.735 1.00 9.42 N ANISOU 2119 N SER B 365 1214 1168 1197 37 31 291 N ATOM 2120 CA SER B 365 12.512 -57.820 19.280 1.00 9.73 C ANISOU 2120 CA SER B 365 1432 1125 1139 -3 69 200 C ATOM 2121 C SER B 365 12.126 -58.023 17.819 1.00 9.11 C ANISOU 2121 C SER B 365 988 1310 1165 43 90 173 C ATOM 2122 O SER B 365 11.194 -57.425 17.310 1.00 10.56 O ANISOU 2122 O SER B 365 1331 1525 1156 -208 20 208 O ATOM 2123 CB SER B 365 12.017 -58.959 20.160 1.00 11.19 C ANISOU 2123 CB SER B 365 1640 1249 1363 78 208 94 C ATOM 2124 OG SER B 365 10.599 -58.952 20.257 1.00 11.71 O ANISOU 2124 OG SER B 365 1710 1189 1549 111 400 94 O ATOM 2125 H SER B 365 11.243 -56.340 19.448 1.00 11.32 H ATOM 2126 HA SER B 365 13.491 -57.816 19.328 1.00 11.69 H ATOM 2127 HB2 SER B 365 12.302 -59.801 19.774 1.00 13.44 H ATOM 2128 HB3 SER B 365 12.394 -58.858 21.048 1.00 13.44 H ATOM 2129 HG SER B 365 10.347 -59.570 20.733 1.00 14.07 H ATOM 2130 N ARG B 366 12.839 -58.934 17.182 1.00 9.15 N ANISOU 2130 N ARG B 366 1207 1156 1113 -46 202 210 N ATOM 2131 CA ARG B 366 12.502 -59.431 15.863 1.00 9.33 C ANISOU 2131 CA ARG B 366 1471 1129 946 106 223 34 C ATOM 2132 C ARG B 366 12.306 -60.933 15.982 1.00 8.82 C ANISOU 2132 C ARG B 366 1413 1020 919 25 90 30 C ATOM 2133 O ARG B 366 13.027 -61.580 16.746 1.00 9.64 O ANISOU 2133 O ARG B 366 1466 1100 1097 7 93 108 O ATOM 2134 CB ARG B 366 13.607 -59.157 14.884 1.00 11.11 C ANISOU 2134 CB ARG B 366 1811 1233 1177 271 459 6 C ATOM 2135 CG ARG B 366 13.327 -59.532 13.495 1.00 14.63 C ANISOU 2135 CG ARG B 366 2122 1652 1783 261 673 -153 C ATOM 2136 CD ARG B 366 14.491 -59.215 12.551 1.00 16.09 C ANISOU 2136 CD ARG B 366 2292 1941 1880 211 197 -184 C ATOM 2137 NE ARG B 366 15.671 -59.941 12.920 1.00 18.15 N ANISOU 2137 NE ARG B 366 2338 1995 2565 320 425 63 N ATOM 2138 CZ ARG B 366 16.906 -59.559 12.672 1.00 19.07 C ANISOU 2138 CZ ARG B 366 2333 2584 2327 730 65 -353 C ATOM 2139 NH1 ARG B 366 17.136 -58.396 12.088 1.00 24.83 N ANISOU 2139 NH1 ARG B 366 2557 2840 4037 874 -161 -969 N ATOM 2140 NH2 ARG B 366 17.936 -60.333 13.044 1.00 21.14 N ANISOU 2140 NH2 ARG B 366 2856 2740 2435 245 492 -151 N ATOM 2141 H ARG B 366 13.550 -59.291 17.507 1.00 10.99 H ATOM 2142 HA ARG B 366 11.673 -59.017 15.543 1.00 11.21 H ATOM 2143 HB2 ARG B 366 13.797 -58.205 14.895 1.00 13.35 H ATOM 2144 HB3 ARG B 366 14.395 -59.648 15.166 1.00 13.35 H ATOM 2145 HG2 ARG B 366 13.159 -60.487 13.454 1.00 17.57 H ATOM 2146 HG3 ARG B 366 12.548 -59.044 13.186 1.00 17.57 H ATOM 2147 HD2 ARG B 366 14.248 -59.469 11.646 1.00 19.32 H ATOM 2148 HD3 ARG B 366 14.689 -58.268 12.593 1.00 19.32 H ATOM 2149 HE ARG B 366 15.549 -60.779 13.391 1.00 21.80 H ATOM 2150 HH11 ARG B 366 16.478 -57.900 11.845 1.00 29.81 H ATOM 2151 HH12 ARG B 366 17.944 -58.145 11.935 1.00 29.81 H ATOM 2152 HH21 ARG B 366 17.790 -61.084 13.435 1.00 25.38 H ATOM 2153 HH22 ARG B 366 18.743 -60.075 12.898 1.00 25.38 H ATOM 2154 N HIS B 367 11.319 -61.416 15.259 1.00 8.77 N ANISOU 2154 N HIS B 367 1399 1052 881 29 91 -50 N ATOM 2155 CA HIS B 367 10.992 -62.842 15.291 1.00 8.62 C ANISOU 2155 CA HIS B 367 1472 1089 714 71 120 10 C ATOM 2156 C HIS B 367 10.840 -63.349 13.895 1.00 9.48 C ANISOU 2156 C HIS B 367 1545 1064 995 105 172 -6 C ATOM 2157 O HIS B 367 10.401 -62.663 12.994 1.00 10.87 O ANISOU 2157 O HIS B 367 2079 1172 880 108 104 41 O ATOM 2158 CB HIS B 367 9.661 -63.056 16.036 1.00 8.97 C ANISOU 2158 CB HIS B 367 1403 1048 957 29 159 -127 C ATOM 2159 CG HIS B 367 9.681 -62.574 17.432 1.00 8.57 C ANISOU 2159 CG HIS B 367 1198 1083 975 66 174 -77 C ATOM 2160 ND1 HIS B 367 9.866 -63.396 18.530 1.00 8.98 N ANISOU 2160 ND1 HIS B 367 1274 1132 1007 38 289 32 N ATOM 2161 CD2 HIS B 367 9.685 -61.312 17.930 1.00 9.77 C ANISOU 2161 CD2 HIS B 367 1560 1216 938 -3 178 63 C ATOM 2162 CE1 HIS B 367 9.922 -62.642 19.615 1.00 9.40 C ANISOU 2162 CE1 HIS B 367 1501 1003 1068 112 296 14 C ATOM 2163 NE2 HIS B 367 9.817 -61.370 19.276 1.00 10.25 N ANISOU 2163 NE2 HIS B 367 1530 1256 1108 38 230 141 N ATOM 2164 H HIS B 367 10.819 -60.949 14.738 1.00 10.54 H ATOM 2165 HA HIS B 367 11.702 -63.344 15.743 1.00 10.36 H ATOM 2166 HB2 HIS B 367 8.959 -62.581 15.566 1.00 10.78 H ATOM 2167 HB3 HIS B 367 9.462 -64.005 16.053 1.00 10.78 H ATOM 2168 HD2 HIS B 367 9.596 -60.534 17.430 1.00 11.74 H ATOM 2169 HE1 HIS B 367 10.008 -62.961 20.485 1.00 11.30 H ATOM 2170 N ASN B 368 11.126 -64.639 13.720 1.00 10.38 N ANISOU 2170 N ASN B 368 1928 1111 904 -29 72 99 N ATOM 2171 CA ASN B 368 10.715 -65.314 12.521 1.00 11.32 C ANISOU 2171 CA ASN B 368 1700 1466 1136 36 73 93 C ATOM 2172 C ASN B 368 9.237 -65.572 12.601 1.00 10.39 C ANISOU 2172 C ASN B 368 1745 1079 1124 -81 31 12 C ATOM 2173 O ASN B 368 8.584 -65.344 13.641 1.00 11.39 O ANISOU 2173 O ASN B 368 1544 1251 1532 15 -70 15 O ATOM 2174 CB ASN B 368 11.523 -66.546 12.182 1.00 12.95 C ANISOU 2174 CB ASN B 368 2155 1480 1286 -70 163 387 C ATOM 2175 CG ASN B 368 11.311 -67.693 13.121 1.00 13.42 C ANISOU 2175 CG ASN B 368 2715 1201 1183 -247 25 144 C ATOM 2176 OD1 ASN B 368 10.373 -67.746 13.918 1.00 12.97 O ANISOU 2176 OD1 ASN B 368 2264 1252 1412 56 -66 34 O ATOM 2177 ND2 ASN B 368 12.220 -68.636 13.020 1.00 19.54 N ANISOU 2177 ND2 ASN B 368 3535 2199 1690 -941 697 -160 N ATOM 2178 H ASN B 368 11.553 -65.130 14.282 1.00 12.47 H ATOM 2179 HA ASN B 368 10.845 -64.689 11.777 1.00 13.60 H ATOM 2180 HB2 ASN B 368 11.278 -66.844 11.292 1.00 15.56 H ATOM 2181 HB3 ASN B 368 12.465 -66.317 12.203 1.00 15.56 H ATOM 2182 HD21 ASN B 368 12.169 -69.428 13.593 1.00 23.46 H ATOM 2183 HD22 ASN B 368 12.949 -68.546 12.372 1.00 23.46 H ATOM 2184 N ILE B 369 8.642 -66.014 11.505 1.00 12.41 N ANISOU 2184 N ILE B 369 1846 1608 1261 271 -89 172 N ATOM 2185 CA ILE B 369 7.217 -66.157 11.556 1.00 14.96 C ANISOU 2185 CA ILE B 369 1878 1978 1828 414 -90 223 C ATOM 2186 C ILE B 369 6.705 -67.230 12.475 1.00 16.11 C ANISOU 2186 C ILE B 369 1992 2277 1853 881 -243 50 C ATOM 2187 O ILE B 369 5.574 -67.225 12.843 1.00 17.20 O ANISOU 2187 O ILE B 369 1663 2306 2567 643 169 -60 O ATOM 2188 CB ILE B 369 6.628 -66.427 10.084 1.00 16.64 C ANISOU 2188 CB ILE B 369 2217 2434 1672 423 -234 289 C ATOM 2189 CG1 ILE B 369 7.327 -67.591 9.319 1.00 20.59 C ANISOU 2189 CG1 ILE B 369 3080 2795 1949 445 -423 -26 C ATOM 2190 CG2 ILE B 369 6.738 -65.194 9.220 1.00 19.05 C ANISOU 2190 CG2 ILE B 369 2162 2703 2372 123 -267 -571 C ATOM 2191 CD1 ILE B 369 6.621 -68.094 8.061 1.00 27.43 C ANISOU 2191 CD1 ILE B 369 3515 3680 3229 221 -135 397 C ATOM 2192 H ILE B 369 9.022 -66.227 10.763 1.00 14.91 H ATOM 2193 HA ILE B 369 6.839 -65.309 11.868 1.00 17.96 H ATOM 2194 HB ILE B 369 5.688 -66.648 10.173 1.00 19.98 H ATOM 2195 HG12 ILE B 369 8.211 -67.293 9.054 1.00 24.73 H ATOM 2196 HG13 ILE B 369 7.410 -68.344 9.923 1.00 24.73 H ATOM 2197 HG21 ILE B 369 6.379 -65.388 8.351 1.00 22.87 H ATOM 2198 HG22 ILE B 369 6.242 -64.480 9.629 1.00 22.87 H ATOM 2199 HG23 ILE B 369 7.663 -64.948 9.145 1.00 22.87 H ATOM 2200 HD11 ILE B 369 7.139 -68.805 7.676 1.00 32.94 H ATOM 2201 HD12 ILE B 369 5.749 -68.414 8.299 1.00 32.94 H ATOM 2202 HD13 ILE B 369 6.544 -67.368 7.436 1.00 32.94 H ATOM 2203 N GLU B 370 7.551 -68.145 12.915 1.00 16.39 N ANISOU 2203 N GLU B 370 2423 1809 1995 507 -630 -80 N ATOM 2204 CA GLU B 370 7.132 -69.069 13.938 1.00 16.63 C ANISOU 2204 CA GLU B 370 2755 1778 1785 679 -379 134 C ATOM 2205 C GLU B 370 7.134 -68.547 15.383 1.00 15.96 C ANISOU 2205 C GLU B 370 2175 1438 2452 545 -433 -315 C ATOM 2206 O GLU B 370 6.600 -69.194 16.293 1.00 17.25 O ANISOU 2206 O GLU B 370 2537 1632 2384 714 -387 -144 O ATOM 2207 CB GLU B 370 8.042 -70.294 13.916 1.00 19.43 C ANISOU 2207 CB GLU B 370 3331 1951 2101 405 -387 544 C ATOM 2208 CG GLU B 370 7.821 -71.079 12.629 1.00 29.68 C ANISOU 2208 CG GLU B 370 4069 3250 3960 252 -131 120 C ATOM 2209 CD GLU B 370 8.816 -72.203 12.431 1.00 37.00 C ANISOU 2209 CD GLU B 370 4457 4237 5363 560 155 196 C ATOM 2210 OE1 GLU B 370 10.048 -71.894 12.492 1.00 41.16 O ANISOU 2210 OE1 GLU B 370 4708 4836 6094 760 133 291 O ATOM 2211 OE2 GLU B 370 8.364 -73.371 12.130 1.00 39.21 O ANISOU 2211 OE2 GLU B 370 5043 4492 5365 420 224 -429 O ATOM 2212 H GLU B 370 8.359 -68.248 12.640 1.00 19.68 H ATOM 2213 HA GLU B 370 6.222 -69.368 13.733 1.00 19.97 H ATOM 2214 HB2 GLU B 370 8.969 -70.013 13.950 1.00 23.33 H ATOM 2215 HB3 GLU B 370 7.831 -70.870 14.668 1.00 23.33 H ATOM 2216 HG2 GLU B 370 6.932 -71.468 12.647 1.00 35.64 H ATOM 2217 HG3 GLU B 370 7.901 -70.474 11.875 1.00 35.64 H ATOM 2218 N GLY B 371 7.759 -67.427 15.615 1.00 12.55 N ANISOU 2218 N GLY B 371 1593 1400 1775 235 -134 80 N ATOM 2219 CA GLY B 371 7.902 -66.823 16.929 1.00 11.69 C ANISOU 2219 CA GLY B 371 1882 1309 1251 65 219 51 C ATOM 2220 C GLY B 371 9.268 -66.851 17.553 1.00 8.96 C ANISOU 2220 C GLY B 371 1271 1050 1082 7 -123 -93 C ATOM 2221 O GLY B 371 9.422 -66.333 18.656 1.00 9.80 O ANISOU 2221 O GLY B 371 1595 1095 1032 -113 100 -82 O ATOM 2222 H GLY B 371 8.135 -66.965 14.995 1.00 15.07 H ATOM 2223 HA2 GLY B 371 7.629 -65.894 16.871 1.00 14.04 H ATOM 2224 HA3 GLY B 371 7.294 -67.269 17.540 1.00 14.04 H ATOM 2225 N ILE B 372 10.250 -67.415 16.884 1.00 9.86 N ANISOU 2225 N ILE B 372 1455 1033 1260 -75 30 -44 N ATOM 2226 CA ILE B 372 11.604 -67.465 17.439 1.00 9.43 C ANISOU 2226 CA ILE B 372 1569 984 1031 -305 62 125 C ATOM 2227 C ILE B 372 12.199 -66.050 17.466 1.00 8.77 C ANISOU 2227 C ILE B 372 1273 957 1101 -191 130 46 C ATOM 2228 O ILE B 372 12.194 -65.355 16.461 1.00 9.91 O ANISOU 2228 O ILE B 372 1593 1095 1078 -14 70 -42 O ATOM 2229 CB ILE B 372 12.491 -68.380 16.605 1.00 11.69 C ANISOU 2229 CB ILE B 372 1813 1202 1427 -191 56 62 C ATOM 2230 CG1 ILE B 372 11.934 -69.776 16.530 1.00 15.38 C ANISOU 2230 CG1 ILE B 372 2569 1439 1835 -607 289 133 C ATOM 2231 CG2 ILE B 372 13.926 -68.371 17.098 1.00 13.85 C ANISOU 2231 CG2 ILE B 372 1968 1536 1757 -578 88 349 C ATOM 2232 CD1 ILE B 372 11.931 -70.510 17.807 1.00 18.58 C ANISOU 2232 CD1 ILE B 372 3120 1966 1973 -121 657 -64 C ATOM 2233 H ILE B 372 10.170 -67.776 16.108 1.00 11.85 H ATOM 2234 HA ILE B 372 11.572 -67.811 18.356 1.00 11.33 H ATOM 2235 HB ILE B 372 12.497 -68.026 15.702 1.00 14.04 H ATOM 2236 HG12 ILE B 372 11.016 -69.725 16.218 1.00 18.47 H ATOM 2237 HG13 ILE B 372 12.464 -70.287 15.899 1.00 18.47 H ATOM 2238 HG21 ILE B 372 14.449 -68.960 16.547 1.00 16.63 H ATOM 2239 HG22 ILE B 372 14.270 -67.478 17.042 1.00 16.63 H ATOM 2240 HG23 ILE B 372 13.945 -68.674 18.009 1.00 16.63 H ATOM 2241 HD11 ILE B 372 11.561 -71.385 17.663 1.00 22.31 H ATOM 2242 HD12 ILE B 372 12.833 -70.585 18.126 1.00 22.31 H ATOM 2243 HD13 ILE B 372 11.397 -70.028 18.443 1.00 22.31 H ATOM 2244 N PHE B 373 12.791 -65.689 18.615 1.00 9.10 N ANISOU 2244 N PHE B 373 1282 1158 1020 -197 -20 1 N ATOM 2245 CA PHE B 373 13.563 -64.456 18.704 1.00 9.50 C ANISOU 2245 CA PHE B 373 1296 1272 1043 -227 140 75 C ATOM 2246 C PHE B 373 14.788 -64.540 17.795 1.00 10.15 C ANISOU 2246 C PHE B 373 1164 1241 1451 -272 -69 188 C ATOM 2247 O PHE B 373 15.651 -65.398 18.001 1.00 11.88 O ANISOU 2247 O PHE B 373 1340 1595 1578 -447 309 107 O ATOM 2248 CB PHE B 373 14.099 -64.240 20.132 1.00 9.74 C ANISOU 2248 CB PHE B 373 1054 1271 1377 -124 -72 103 C ATOM 2249 CG PHE B 373 13.068 -63.734 21.139 1.00 9.01 C ANISOU 2249 CG PHE B 373 1117 1285 1021 -138 -3 112 C ATOM 2250 CD1 PHE B 373 12.478 -64.612 22.005 1.00 10.13 C ANISOU 2250 CD1 PHE B 373 1308 1415 1127 -76 -27 118 C ATOM 2251 CD2 PHE B 373 12.779 -62.386 21.246 1.00 10.87 C ANISOU 2251 CD2 PHE B 373 1522 1433 1176 -101 103 111 C ATOM 2252 CE1 PHE B 373 11.612 -64.136 22.990 1.00 10.55 C ANISOU 2252 CE1 PHE B 373 1393 1463 1151 49 112 -16 C ATOM 2253 CE2 PHE B 373 11.909 -61.925 22.222 1.00 11.42 C ANISOU 2253 CE2 PHE B 373 1888 1361 1092 -92 245 142 C ATOM 2254 CZ PHE B 373 11.317 -62.807 23.109 1.00 11.71 C ANISOU 2254 CZ PHE B 373 1609 1570 1271 -110 169 184 C ATOM 2255 H PHE B 373 12.757 -66.139 19.346 1.00 10.94 H ATOM 2256 HA PHE B 373 13.014 -63.688 18.442 1.00 11.42 H ATOM 2257 HB2 PHE B 373 14.441 -65.086 20.463 1.00 11.71 H ATOM 2258 HB3 PHE B 373 14.818 -63.590 20.097 1.00 11.71 H ATOM 2259 HD1 PHE B 373 12.688 -65.517 21.966 1.00 12.17 H ATOM 2260 HD2 PHE B 373 13.194 -61.781 20.676 1.00 13.06 H ATOM 2261 HE1 PHE B 373 11.205 -64.742 23.566 1.00 12.67 H ATOM 2262 HE2 PHE B 373 11.714 -61.017 22.275 1.00 13.72 H ATOM 2263 HZ PHE B 373 10.703 -62.511 23.741 1.00 14.07 H ATOM 2264 N THR B 374 14.909 -63.629 16.860 1.00 9.83 N ANISOU 2264 N THR B 374 1213 1287 1235 -122 244 210 N ATOM 2265 CA THR B 374 16.094 -63.520 16.007 1.00 11.35 C ANISOU 2265 CA THR B 374 1449 1581 1284 -42 343 194 C ATOM 2266 C THR B 374 16.867 -62.234 16.220 1.00 12.75 C ANISOU 2266 C THR B 374 1370 1932 1541 -6 427 456 C ATOM 2267 O THR B 374 17.984 -62.101 15.724 1.00 15.89 O ANISOU 2267 O THR B 374 1457 2386 2197 241 703 798 O ATOM 2268 CB THR B 374 15.734 -63.645 14.520 1.00 12.35 C ANISOU 2268 CB THR B 374 1666 1574 1453 -3 318 126 C ATOM 2269 OG1 THR B 374 14.873 -62.557 14.192 1.00 13.34 O ANISOU 2269 OG1 THR B 374 2113 1552 1405 33 179 52 O ATOM 2270 CG2 THR B 374 15.011 -64.981 14.218 1.00 13.61 C ANISOU 2270 CG2 THR B 374 1919 1616 1635 -117 323 182 C ATOM 2271 H THR B 374 14.308 -63.039 16.687 1.00 11.81 H ATOM 2272 HA THR B 374 16.697 -64.261 16.224 1.00 13.64 H ATOM 2273 HB THR B 374 16.540 -63.598 13.983 1.00 14.83 H ATOM 2274 HG1 THR B 374 14.662 -62.596 13.400 1.00 16.03 H ATOM 2275 HG21 THR B 374 14.798 -65.034 13.284 1.00 16.34 H ATOM 2276 HG22 THR B 374 15.578 -65.720 14.451 1.00 16.34 H ATOM 2277 HG23 THR B 374 14.200 -65.037 14.728 1.00 16.34 H ATOM 2278 N PHE B 375 16.353 -61.331 17.024 1.00 11.68 N ANISOU 2278 N PHE B 375 1370 1680 1387 186 312 328 N ATOM 2279 CA PHE B 375 17.062 -60.127 17.425 1.00 12.64 C ANISOU 2279 CA PHE B 375 1447 1719 1637 189 285 406 C ATOM 2280 C PHE B 375 16.386 -59.645 18.739 1.00 10.65 C ANISOU 2280 C PHE B 375 1159 1580 1308 228 -2 218 C ATOM 2281 O PHE B 375 15.171 -59.700 18.852 1.00 10.38 O ANISOU 2281 O PHE B 375 1040 1412 1492 61 29 143 O ATOM 2282 CB PHE B 375 16.944 -59.011 16.398 1.00 16.36 C ANISOU 2282 CB PHE B 375 2239 1783 2195 810 348 215 C ATOM 2283 CG PHE B 375 17.572 -57.764 16.904 1.00 22.19 C ANISOU 2283 CG PHE B 375 2796 2678 2955 988 1106 68 C ATOM 2284 CD1 PHE B 375 18.974 -57.662 16.981 1.00 26.75 C ANISOU 2284 CD1 PHE B 375 3036 3093 4036 1218 246 97 C ATOM 2285 CD2 PHE B 375 16.826 -56.766 17.465 1.00 19.19 C ANISOU 2285 CD2 PHE B 375 3028 2050 2212 574 276 58 C ATOM 2286 CE1 PHE B 375 19.578 -56.562 17.534 1.00 30.46 C ANISOU 2286 CE1 PHE B 375 3659 3423 4493 526 -69 232 C ATOM 2287 CE2 PHE B 375 17.456 -55.593 17.979 1.00 24.83 C ANISOU 2287 CE2 PHE B 375 3464 2490 3481 379 294 947 C ATOM 2288 CZ PHE B 375 18.806 -55.556 18.046 1.00 28.05 C ANISOU 2288 CZ PHE B 375 3620 3012 4028 675 -37 1043 C ATOM 2289 H PHE B 375 15.566 -61.391 17.365 1.00 14.03 H ATOM 2290 HA PHE B 375 18.008 -60.322 17.593 1.00 15.19 H ATOM 2291 HB2 PHE B 375 17.398 -59.275 15.582 1.00 19.65 H ATOM 2292 HB3 PHE B 375 16.007 -58.834 16.221 1.00 19.65 H ATOM 2293 HD1 PHE B 375 19.500 -58.358 16.659 1.00 32.12 H ATOM 2294 HD2 PHE B 375 15.897 -56.812 17.429 1.00 23.04 H ATOM 2295 HE1 PHE B 375 20.506 -56.496 17.550 1.00 36.57 H ATOM 2296 HE2 PHE B 375 16.946 -54.904 18.341 1.00 29.81 H ATOM 2297 HZ PHE B 375 19.221 -54.792 18.380 1.00 33.68 H ATOM 2298 N VAL B 376 17.164 -59.239 19.706 1.00 11.97 N ANISOU 2298 N VAL B 376 1183 1762 1602 180 277 389 N ATOM 2299 CA VAL B 376 16.646 -58.758 20.965 1.00 11.70 C ANISOU 2299 CA VAL B 376 1283 1580 1583 308 10 234 C ATOM 2300 C VAL B 376 17.429 -57.531 21.424 1.00 11.28 C ANISOU 2300 C VAL B 376 1323 1646 1315 185 44 337 C ATOM 2301 O VAL B 376 18.644 -57.562 21.605 1.00 13.86 O ANISOU 2301 O VAL B 376 1039 2032 2197 181 -14 467 O ATOM 2302 CB VAL B 376 16.776 -59.828 22.041 1.00 17.07 C ANISOU 2302 CB VAL B 376 2755 1910 1821 780 210 325 C ATOM 2303 CG1 VAL B 376 16.076 -59.370 23.298 1.00 21.10 C ANISOU 2303 CG1 VAL B 376 3336 2548 2131 1118 367 674 C ATOM 2304 CG2 VAL B 376 16.198 -61.215 21.564 1.00 18.10 C ANISOU 2304 CG2 VAL B 376 2672 1923 2281 293 -87 -191 C ATOM 2305 H VAL B 376 18.022 -59.229 19.660 1.00 14.37 H ATOM 2306 HA VAL B 376 15.702 -58.515 20.869 1.00 14.06 H ATOM 2307 HB VAL B 376 17.724 -59.953 22.253 1.00 20.50 H ATOM 2308 HG11 VAL B 376 16.163 -60.050 23.969 1.00 25.33 H ATOM 2309 HG12 VAL B 376 16.483 -58.555 23.602 1.00 25.33 H ATOM 2310 HG13 VAL B 376 15.149 -59.221 23.101 1.00 25.33 H ATOM 2311 HG21 VAL B 376 16.301 -61.855 22.271 1.00 21.73 H ATOM 2312 HG22 VAL B 376 15.268 -61.108 21.350 1.00 21.73 H ATOM 2313 HG23 VAL B 376 16.683 -61.503 20.787 1.00 21.73 H ATOM 2314 N ASP B 377 16.750 -56.431 21.592 1.00 11.11 N ANISOU 2314 N ASP B 377 1215 1544 1463 298 163 128 N ATOM 2315 CA ASP B 377 17.316 -55.199 22.123 1.00 12.65 C ANISOU 2315 CA ASP B 377 1697 1679 1431 398 373 246 C ATOM 2316 C ASP B 377 17.664 -55.371 23.595 1.00 11.92 C ANISOU 2316 C ASP B 377 1360 1702 1467 233 268 153 C ATOM 2317 O ASP B 377 16.903 -55.913 24.383 1.00 12.18 O ANISOU 2317 O ASP B 377 1729 1515 1385 418 148 126 O ATOM 2318 CB ASP B 377 16.159 -54.165 21.821 1.00 15.38 C ANISOU 2318 CB ASP B 377 2077 1732 2036 252 173 189 C ATOM 2319 CG ASP B 377 16.045 -52.966 22.731 1.00 12.45 C ANISOU 2319 CG ASP B 377 1946 1346 1437 400 104 -111 C ATOM 2320 OD1 ASP B 377 16.975 -52.564 23.478 1.00 14.15 O ANISOU 2320 OD1 ASP B 377 2477 1389 1509 453 22 -170 O ATOM 2321 OD2 ASP B 377 14.946 -52.399 22.672 1.00 13.33 O ANISOU 2321 OD2 ASP B 377 1847 1370 1846 559 346 6 O ATOM 2322 H ASP B 377 15.916 -56.358 21.398 1.00 13.35 H ATOM 2323 HA ASP B 377 18.121 -54.947 21.622 1.00 15.20 H ATOM 2324 HB2 ASP B 377 16.286 -53.827 20.920 1.00 18.48 H ATOM 2325 HB3 ASP B 377 15.313 -54.638 21.867 1.00 18.48 H ATOM 2326 N HIS B 378 18.828 -54.880 23.998 1.00 12.89 N ANISOU 2326 N HIS B 378 1365 1942 1590 279 190 30 N ATOM 2327 CA HIS B 378 19.355 -55.039 25.367 1.00 13.88 C ANISOU 2327 CA HIS B 378 1378 2038 1859 308 65 -25 C ATOM 2328 C HIS B 378 18.527 -54.386 26.443 1.00 12.92 C ANISOU 2328 C HIS B 378 1314 1880 1716 369 -134 118 C ATOM 2329 O HIS B 378 18.746 -54.690 27.620 1.00 13.18 O ANISOU 2329 O HIS B 378 1614 1849 1546 327 -207 122 O ATOM 2330 CB HIS B 378 20.804 -54.586 25.391 1.00 16.76 C ANISOU 2330 CB HIS B 378 1955 2429 1983 612 8 95 C ATOM 2331 CG HIS B 378 21.494 -54.782 26.716 1.00 23.30 C ANISOU 2331 CG HIS B 378 2621 2997 3234 425 -19 448 C ATOM 2332 ND1 HIS B 378 21.480 -53.827 27.717 1.00 28.03 N ANISOU 2332 ND1 HIS B 378 3222 3527 3902 558 -528 365 N ATOM 2333 CD2 HIS B 378 22.238 -55.821 27.195 1.00 27.23 C ANISOU 2333 CD2 HIS B 378 3398 3707 3239 621 -357 58 C ATOM 2334 CE1 HIS B 378 22.132 -54.286 28.776 1.00 27.01 C ANISOU 2334 CE1 HIS B 378 3303 3619 3339 699 -707 -45 C ATOM 2335 NE2 HIS B 378 22.646 -55.471 28.467 1.00 29.98 N ANISOU 2335 NE2 HIS B 378 3470 4124 3799 850 -238 -176 N ATOM 2336 H HIS B 378 19.356 -54.435 23.485 1.00 15.48 H ATOM 2337 HA HIS B 378 19.361 -55.998 25.569 1.00 16.68 H ATOM 2338 HB2 HIS B 378 21.298 -55.087 24.724 1.00 20.12 H ATOM 2339 HB3 HIS B 378 20.837 -53.639 25.179 1.00 20.12 H ATOM 2340 HD2 HIS B 378 22.444 -56.608 26.745 1.00 32.69 H ATOM 2341 HE1 HIS B 378 22.277 -53.822 29.569 1.00 32.42 H ATOM 2342 N ARG B 379 17.548 -53.561 26.082 1.00 11.60 N ANISOU 2342 N ARG B 379 1471 1683 1254 447 125 95 N ATOM 2343 CA ARG B 379 16.573 -53.090 27.065 1.00 11.18 C ANISOU 2343 CA ARG B 379 1501 1366 1383 473 -116 79 C ATOM 2344 C ARG B 379 15.724 -54.221 27.629 1.00 10.87 C ANISOU 2344 C ARG B 379 1569 1453 1107 295 39 130 C ATOM 2345 O ARG B 379 15.026 -54.027 28.636 1.00 12.01 O ANISOU 2345 O ARG B 379 1993 1329 1239 168 270 95 O ATOM 2346 CB ARG B 379 15.677 -51.986 26.454 1.00 11.96 C ANISOU 2346 CB ARG B 379 1685 1352 1506 329 140 100 C ATOM 2347 CG ARG B 379 16.416 -50.698 26.192 1.00 12.88 C ANISOU 2347 CG ARG B 379 1725 1507 1661 427 72 -60 C ATOM 2348 CD ARG B 379 15.488 -49.569 25.609 1.00 13.57 C ANISOU 2348 CD ARG B 379 2045 1550 1561 443 114 46 C ATOM 2349 NE ARG B 379 14.911 -50.020 24.360 1.00 12.86 N ANISOU 2349 NE ARG B 379 2196 1228 1461 369 316 -27 N ATOM 2350 CZ ARG B 379 13.976 -49.358 23.675 1.00 12.66 C ANISOU 2350 CZ ARG B 379 2450 966 1395 317 536 -189 C ATOM 2351 NH1 ARG B 379 13.497 -48.214 24.137 1.00 13.24 N ANISOU 2351 NH1 ARG B 379 2459 1300 1272 140 266 16 N ATOM 2352 NH2 ARG B 379 13.496 -49.842 22.544 1.00 13.60 N ANISOU 2352 NH2 ARG B 379 2404 1337 1427 211 324 15 N ATOM 2353 H ARG B 379 17.426 -53.262 25.284 1.00 13.94 H ATOM 2354 HA ARG B 379 17.060 -52.689 27.814 1.00 13.44 H ATOM 2355 HB2 ARG B 379 15.319 -52.303 25.610 1.00 14.36 H ATOM 2356 HB3 ARG B 379 14.952 -51.793 27.069 1.00 14.36 H ATOM 2357 HG2 ARG B 379 16.793 -50.375 27.026 1.00 15.47 H ATOM 2358 HG3 ARG B 379 17.124 -50.866 25.551 1.00 15.47 H ATOM 2359 HD2 ARG B 379 14.770 -49.382 26.233 1.00 16.30 H ATOM 2360 HD3 ARG B 379 16.012 -48.771 25.439 1.00 16.30 H ATOM 2361 HE ARG B 379 15.227 -50.860 23.994 1.00 15.44 H ATOM 2362 HH11 ARG B 379 13.797 -47.889 24.874 1.00 15.90 H ATOM 2363 HH12 ARG B 379 12.892 -47.791 23.695 1.00 15.90 H ATOM 2364 HH21 ARG B 379 13.795 -50.586 22.233 1.00 16.34 H ATOM 2365 HH22 ARG B 379 12.891 -49.408 22.113 1.00 16.34 H ATOM 2366 N CYS B 380 15.842 -55.428 27.070 1.00 10.28 N ANISOU 2366 N CYS B 380 1319 1288 1298 387 78 84 N ATOM 2367 CA CYS B 380 15.166 -56.588 27.673 1.00 10.85 C ANISOU 2367 CA CYS B 380 1473 1332 1319 346 -43 88 C ATOM 2368 C CYS B 380 15.637 -56.814 29.088 1.00 10.85 C ANISOU 2368 C CYS B 380 1388 1261 1474 530 70 173 C ATOM 2369 O CYS B 380 14.865 -57.346 29.889 1.00 11.88 O ANISOU 2369 O CYS B 380 1544 1478 1493 461 166 103 O ATOM 2370 CB CYS B 380 15.409 -57.812 26.784 1.00 11.77 C ANISOU 2370 CB CYS B 380 1628 1360 1485 225 23 -83 C ATOM 2371 SG CYS B 380 17.107 -58.342 26.604 1.00 12.93 S ANISOU 2371 SG CYS B 380 1846 1536 1531 143 15 182 S ATOM 2372 H CYS B 380 16.294 -55.603 26.359 1.00 12.35 H ATOM 2373 HA CYS B 380 14.202 -56.419 27.698 1.00 13.04 H ATOM 2374 HB2 CYS B 380 14.913 -58.559 27.154 1.00 14.14 H ATOM 2375 HB3 CYS B 380 15.074 -57.614 25.896 1.00 14.14 H ATOM 2376 HG CYS B 380 17.596 -58.656 27.812 1.00 15.53 H ATOM 2377 N VAL B 381 16.900 -56.498 29.409 1.00 11.18 N ANISOU 2377 N VAL B 381 1726 1439 1082 477 -23 67 N ATOM 2378 CA VAL B 381 17.390 -56.822 30.755 1.00 12.33 C ANISOU 2378 CA VAL B 381 1748 1628 1310 303 -260 229 C ATOM 2379 C VAL B 381 16.541 -56.045 31.757 1.00 13.33 C ANISOU 2379 C VAL B 381 2360 1403 1301 608 -167 39 C ATOM 2380 O VAL B 381 16.072 -56.585 32.743 1.00 15.63 O ANISOU 2380 O VAL B 381 3020 1569 1350 536 78 111 O ATOM 2381 CB VAL B 381 18.860 -56.496 30.944 1.00 14.67 C ANISOU 2381 CB VAL B 381 1899 2168 1509 375 -399 136 C ATOM 2382 CG1 VAL B 381 19.280 -56.897 32.328 1.00 19.47 C ANISOU 2382 CG1 VAL B 381 2266 3024 2106 314 -536 -190 C ATOM 2383 CG2 VAL B 381 19.734 -57.169 29.908 1.00 16.36 C ANISOU 2383 CG2 VAL B 381 2059 2060 2098 384 -439 -72 C ATOM 2384 H VAL B 381 17.469 -56.112 28.891 1.00 13.43 H ATOM 2385 HA VAL B 381 17.265 -57.779 30.922 1.00 14.81 H ATOM 2386 HB VAL B 381 18.985 -55.527 30.860 1.00 17.62 H ATOM 2387 HG11 VAL B 381 20.210 -56.691 32.445 1.00 23.37 H ATOM 2388 HG12 VAL B 381 18.754 -56.410 32.967 1.00 23.37 H ATOM 2389 HG13 VAL B 381 19.138 -57.841 32.437 1.00 23.37 H ATOM 2390 HG21 VAL B 381 20.650 -56.932 30.071 1.00 19.65 H ATOM 2391 HG22 VAL B 381 19.624 -58.120 29.977 1.00 19.65 H ATOM 2392 HG23 VAL B 381 19.468 -56.871 29.035 1.00 19.65 H ATOM 2393 N ALA B 382 16.333 -54.741 31.512 1.00 13.68 N ANISOU 2393 N ALA B 382 2250 1503 1445 610 232 336 N ATOM 2394 CA ALA B 382 15.554 -53.949 32.391 1.00 15.26 C ANISOU 2394 CA ALA B 382 2656 1377 1766 615 620 304 C ATOM 2395 C ALA B 382 14.080 -54.340 32.407 1.00 14.32 C ANISOU 2395 C ALA B 382 2497 1438 1505 151 421 92 C ATOM 2396 O ALA B 382 13.398 -54.138 33.396 1.00 17.28 O ANISOU 2396 O ALA B 382 2929 1977 1659 256 638 543 O ATOM 2397 CB ALA B 382 15.682 -52.409 31.981 1.00 19.75 C ANISOU 2397 CB ALA B 382 2946 1939 2620 862 508 618 C ATOM 2398 H ALA B 382 16.645 -54.316 30.833 1.00 16.43 H ATOM 2399 HA ALA B 382 15.903 -54.048 33.302 1.00 18.33 H ATOM 2400 HB1 ALA B 382 15.152 -51.882 32.581 1.00 23.71 H ATOM 2401 HB2 ALA B 382 16.604 -52.147 32.039 1.00 23.71 H ATOM 2402 HB3 ALA B 382 15.367 -52.299 31.081 1.00 23.71 H ATOM 2403 N THR B 383 13.572 -54.846 31.324 1.00 13.17 N ANISOU 2403 N THR B 383 2123 1397 1483 444 394 232 N ATOM 2404 CA THR B 383 12.119 -55.075 31.175 1.00 13.84 C ANISOU 2404 CA THR B 383 2072 1466 1722 328 735 143 C ATOM 2405 C THR B 383 11.766 -56.455 31.795 1.00 12.64 C ANISOU 2405 C THR B 383 1910 1361 1532 199 597 206 C ATOM 2406 O THR B 383 10.778 -56.535 32.538 1.00 13.20 O ANISOU 2406 O THR B 383 1911 1407 1696 10 551 107 O ATOM 2407 CB THR B 383 11.714 -55.077 29.665 1.00 13.01 C ANISOU 2407 CB THR B 383 1872 1395 1676 267 151 -137 C ATOM 2408 OG1 THR B 383 12.108 -53.866 29.027 1.00 14.99 O ANISOU 2408 OG1 THR B 383 2212 1489 1993 195 432 -259 O ATOM 2409 CG2 THR B 383 10.175 -55.123 29.538 1.00 15.49 C ANISOU 2409 CG2 THR B 383 2061 1665 2160 73 426 44 C ATOM 2410 H THR B 383 14.033 -55.078 30.636 1.00 15.81 H ATOM 2411 HA THR B 383 11.617 -54.374 31.642 1.00 16.63 H ATOM 2412 HB THR B 383 12.099 -55.842 29.209 1.00 15.63 H ATOM 2413 HG1 THR B 383 12.921 -53.774 29.077 1.00 18.00 H ATOM 2414 HG21 THR B 383 9.922 -55.125 28.612 1.00 18.61 H ATOM 2415 HG22 THR B 383 9.835 -55.917 29.956 1.00 18.61 H ATOM 2416 HG23 THR B 383 9.788 -54.355 29.966 1.00 18.61 H ATOM 2417 N VAL B 384 12.506 -57.495 31.470 1.00 12.04 N ANISOU 2417 N VAL B 384 1672 1292 1612 327 466 275 N ATOM 2418 CA VAL B 384 12.151 -58.861 31.899 1.00 10.89 C ANISOU 2418 CA VAL B 384 1514 1164 1459 126 293 6 C ATOM 2419 C VAL B 384 13.291 -59.597 32.595 1.00 11.89 C ANISOU 2419 C VAL B 384 1760 1374 1385 157 474 117 C ATOM 2420 O VAL B 384 13.079 -60.711 33.036 1.00 11.30 O ANISOU 2420 O VAL B 384 1770 1333 1191 270 184 -24 O ATOM 2421 CB VAL B 384 11.590 -59.680 30.717 1.00 11.02 C ANISOU 2421 CB VAL B 384 1602 1260 1327 -30 305 -2 C ATOM 2422 CG1 VAL B 384 10.272 -59.172 30.279 1.00 12.92 C ANISOU 2422 CG1 VAL B 384 1683 1454 1772 18 281 -91 C ATOM 2423 CG2 VAL B 384 12.545 -59.706 29.502 1.00 11.88 C ANISOU 2423 CG2 VAL B 384 1713 1448 1353 30 164 160 C ATOM 2424 H VAL B 384 13.225 -57.452 31.000 1.00 14.47 H ATOM 2425 HA VAL B 384 11.427 -58.784 32.555 1.00 13.08 H ATOM 2426 HB VAL B 384 11.466 -60.605 31.012 1.00 13.24 H ATOM 2427 HG11 VAL B 384 9.960 -59.707 29.545 1.00 15.52 H ATOM 2428 HG12 VAL B 384 9.656 -59.232 31.013 1.00 15.52 H ATOM 2429 HG13 VAL B 384 10.366 -58.258 30.002 1.00 15.52 H ATOM 2430 HG21 VAL B 384 12.145 -60.226 28.801 1.00 14.27 H ATOM 2431 HG22 VAL B 384 12.690 -58.806 29.199 1.00 14.27 H ATOM 2432 HG23 VAL B 384 13.379 -60.099 29.768 1.00 14.27 H ATOM 2433 N GLY B 385 14.473 -59.003 32.655 1.00 11.95 N ANISOU 2433 N GLY B 385 1722 1406 1413 167 158 -1 N ATOM 2434 CA GLY B 385 15.563 -59.526 33.460 1.00 12.22 C ANISOU 2434 CA GLY B 385 1731 1526 1386 207 125 156 C ATOM 2435 C GLY B 385 16.512 -60.488 32.782 1.00 11.94 C ANISOU 2435 C GLY B 385 1573 1486 1477 348 -201 78 C ATOM 2436 O GLY B 385 17.463 -60.876 33.410 1.00 15.15 O ANISOU 2436 O GLY B 385 1658 2206 1890 113 -537 210 O ATOM 2437 H GLY B 385 14.672 -58.282 32.230 1.00 14.35 H ATOM 2438 HA2 GLY B 385 16.089 -58.780 33.788 1.00 14.68 H ATOM 2439 HA3 GLY B 385 15.186 -59.981 34.229 1.00 14.68 H ATOM 2440 N TYR B 386 16.232 -60.886 31.552 1.00 11.54 N ANISOU 2440 N TYR B 386 1471 1687 1225 205 -115 143 N ATOM 2441 CA TYR B 386 17.094 -61.762 30.778 1.00 11.62 C ANISOU 2441 CA TYR B 386 1391 1522 1500 20 76 157 C ATOM 2442 C TYR B 386 18.106 -60.977 29.973 1.00 12.21 C ANISOU 2442 C TYR B 386 1284 1530 1827 289 -153 -6 C ATOM 2443 O TYR B 386 17.837 -59.906 29.469 1.00 13.65 O ANISOU 2443 O TYR B 386 1760 1537 1888 260 138 -162 O ATOM 2444 CB TYR B 386 16.261 -62.559 29.771 1.00 11.37 C ANISOU 2444 CB TYR B 386 1439 1408 1475 192 235 98 C ATOM 2445 CG TYR B 386 15.274 -63.451 30.427 1.00 11.23 C ANISOU 2445 CG TYR B 386 1279 1605 1384 -32 94 170 C ATOM 2446 CD1 TYR B 386 15.616 -64.721 30.851 1.00 11.32 C ANISOU 2446 CD1 TYR B 386 1146 1577 1578 24 75 -56 C ATOM 2447 CD2 TYR B 386 13.926 -63.043 30.547 1.00 11.78 C ANISOU 2447 CD2 TYR B 386 1389 1521 1566 39 92 155 C ATOM 2448 CE1 TYR B 386 14.614 -65.555 31.372 1.00 12.08 C ANISOU 2448 CE1 TYR B 386 1326 1652 1610 100 29 30 C ATOM 2449 CE2 TYR B 386 12.976 -63.876 31.008 1.00 11.54 C ANISOU 2449 CE2 TYR B 386 1577 1374 1433 175 234 96 C ATOM 2450 CZ TYR B 386 13.283 -65.136 31.436 1.00 10.12 C ANISOU 2450 CZ TYR B 386 1153 1390 1303 136 70 7 C ATOM 2451 OH TYR B 386 12.330 -65.981 31.958 1.00 11.47 O ANISOU 2451 OH TYR B 386 1452 1472 1435 90 179 66 O ATOM 2452 H TYR B 386 15.521 -60.653 31.129 1.00 13.86 H ATOM 2453 HA TYR B 386 17.566 -62.385 31.371 1.00 13.95 H ATOM 2454 HB2 TYR B 386 15.776 -61.940 29.203 1.00 13.66 H ATOM 2455 HB3 TYR B 386 16.854 -63.108 29.234 1.00 13.66 H ATOM 2456 HD1 TYR B 386 16.492 -65.025 30.774 1.00 13.60 H ATOM 2457 HD2 TYR B 386 13.675 -62.210 30.216 1.00 14.15 H ATOM 2458 HE1 TYR B 386 14.836 -66.413 31.655 1.00 14.51 H ATOM 2459 HE2 TYR B 386 12.099 -63.575 31.072 1.00 13.86 H ATOM 2460 HH TYR B 386 11.756 -66.139 31.394 1.00 13.78 H ATOM 2461 N GLN B 387 19.295 -61.550 29.817 1.00 13.10 N ANISOU 2461 N GLN B 387 1338 1796 1845 117 -60 -118 N ATOM 2462 CA GLN B 387 20.222 -61.105 28.792 1.00 14.02 C ANISOU 2462 CA GLN B 387 1565 1845 1915 261 2 -128 C ATOM 2463 C GLN B 387 19.703 -61.459 27.415 1.00 13.18 C ANISOU 2463 C GLN B 387 1294 1810 1905 65 114 -162 C ATOM 2464 O GLN B 387 19.010 -62.449 27.283 1.00 13.59 O ANISOU 2464 O GLN B 387 1494 1832 1836 188 130 36 O ATOM 2465 CB GLN B 387 21.598 -61.724 29.002 1.00 16.43 C ANISOU 2465 CB GLN B 387 1829 2360 2052 171 -21 21 C ATOM 2466 CG GLN B 387 22.242 -61.354 30.361 1.00 22.40 C ANISOU 2466 CG GLN B 387 2258 2958 3296 83 -259 337 C ATOM 2467 CD GLN B 387 22.612 -59.879 30.437 1.00 23.58 C ANISOU 2467 CD GLN B 387 2496 3373 3090 71 -689 573 C ATOM 2468 OE1 GLN B 387 22.987 -59.281 29.448 1.00 28.25 O ANISOU 2468 OE1 GLN B 387 2693 3510 4532 523 -134 605 O ATOM 2469 NE2 GLN B 387 22.367 -59.281 31.568 1.00 27.04 N ANISOU 2469 NE2 GLN B 387 3006 3496 3772 -88 -1128 710 N ATOM 2470 H GLN B 387 19.588 -62.203 30.295 1.00 15.74 H ATOM 2471 HA GLN B 387 20.314 -60.130 28.843 1.00 16.83 H ATOM 2472 HB2 GLN B 387 21.516 -62.689 28.965 1.00 19.73 H ATOM 2473 HB3 GLN B 387 22.191 -61.416 28.298 1.00 19.73 H ATOM 2474 HG2 GLN B 387 21.612 -61.544 31.073 1.00 26.90 H ATOM 2475 HG3 GLN B 387 23.051 -61.874 30.482 1.00 26.90 H ATOM 2476 HE21 GLN B 387 22.557 -58.447 31.664 1.00 32.46 H ATOM 2477 HE22 GLN B 387 22.016 -59.718 32.219 1.00 32.46 H ATOM 2478 N PRO B 388 20.049 -60.668 26.395 1.00 14.62 N ANISOU 2478 N PRO B 388 1560 2027 1967 169 130 -142 N ATOM 2479 CA PRO B 388 19.588 -61.051 25.069 1.00 15.15 C ANISOU 2479 CA PRO B 388 1736 2037 1984 106 136 -143 C ATOM 2480 C PRO B 388 19.843 -62.505 24.667 1.00 14.38 C ANISOU 2480 C PRO B 388 1365 2339 1761 25 -111 19 C ATOM 2481 O PRO B 388 19.000 -63.090 24.049 1.00 15.41 O ANISOU 2481 O PRO B 388 1688 2485 1681 -39 -106 65 O ATOM 2482 CB PRO B 388 20.328 -60.072 24.144 1.00 18.84 C ANISOU 2482 CB PRO B 388 2398 2395 2365 115 70 -654 C ATOM 2483 CG PRO B 388 20.533 -58.857 24.989 1.00 20.32 C ANISOU 2483 CG PRO B 388 2942 2386 2390 168 754 -416 C ATOM 2484 CD PRO B 388 20.760 -59.384 26.410 1.00 16.62 C ANISOU 2484 CD PRO B 388 1976 1915 2425 361 427 -290 C ATOM 2485 HA PRO B 388 18.626 -60.877 24.997 1.00 18.20 H ATOM 2486 HB2 PRO B 388 21.178 -60.453 23.873 1.00 22.62 H ATOM 2487 HB3 PRO B 388 19.777 -59.867 23.372 1.00 22.62 H ATOM 2488 HG2 PRO B 388 21.312 -58.369 24.676 1.00 24.39 H ATOM 2489 HG3 PRO B 388 19.742 -58.297 24.954 1.00 24.39 H ATOM 2490 HD2 PRO B 388 21.706 -59.522 26.575 1.00 19.96 H ATOM 2491 HD3 PRO B 388 20.366 -58.784 27.063 1.00 19.96 H ATOM 2492 N AGLN B 389 21.018 -63.050 25.019 0.43 15.80 N ANISOU 2492 N AGLN B 389 1653 2419 1932 140 -7 46 N ATOM 2493 N BGLN B 389 21.017 -63.020 25.032 0.57 14.72 N ANISOU 2493 N BGLN B 389 1196 2698 1699 69 -119 139 N ATOM 2494 CA AGLN B 389 21.338 -64.442 24.674 0.43 16.61 C ANISOU 2494 CA AGLN B 389 1745 2440 2126 -83 -97 219 C ATOM 2495 CA BGLN B 389 21.368 -64.397 24.695 0.57 15.67 C ANISOU 2495 CA BGLN B 389 1355 2631 1967 -257 73 353 C ATOM 2496 C AGLN B 389 20.382 -65.464 25.298 0.43 16.27 C ANISOU 2496 C AGLN B 389 1783 2302 2097 -88 54 353 C ATOM 2497 C BGLN B 389 20.526 -65.487 25.396 0.57 15.12 C ANISOU 2497 C BGLN B 389 1573 2506 1667 41 -152 449 C ATOM 2498 O AGLN B 389 20.238 -66.573 24.778 0.43 16.56 O ANISOU 2498 O AGLN B 389 1738 2152 2402 -395 -448 835 O ATOM 2499 O BGLN B 389 20.592 -66.662 25.006 0.57 18.47 O ANISOU 2499 O BGLN B 389 1895 2499 2622 -178 253 416 O ATOM 2500 CB AGLN B 389 22.797 -64.816 25.040 0.43 20.85 C ANISOU 2500 CB AGLN B 389 2335 2629 2960 -118 44 192 C ATOM 2501 CB BGLN B 389 22.849 -64.648 25.016 0.57 21.32 C ANISOU 2501 CB BGLN B 389 2176 2817 3108 -555 75 231 C ATOM 2502 CG AGLN B 389 23.106 -66.305 24.851 0.43 23.65 C ANISOU 2502 CG AGLN B 389 2863 3060 3063 -204 56 -53 C ATOM 2503 CG BGLN B 389 23.091 -64.537 26.505 0.57 21.96 C ANISOU 2503 CG BGLN B 389 2560 3178 2608 -421 -206 -229 C ATOM 2504 CD AGLN B 389 24.560 -66.718 25.072 0.43 28.51 C ANISOU 2504 CD AGLN B 389 3530 3640 3663 -108 111 237 C ATOM 2505 CD BGLN B 389 24.565 -64.382 26.923 0.57 30.44 C ANISOU 2505 CD BGLN B 389 3483 3932 4153 -211 48 161 C ATOM 2506 OE1AGLN B 389 25.066 -67.623 24.383 0.43 30.69 O ANISOU 2506 OE1AGLN B 389 3779 3815 4067 -255 82 256 O ATOM 2507 OE1BGLN B 389 25.332 -65.341 26.861 0.57 32.27 O ANISOU 2507 OE1BGLN B 389 3657 4100 4506 -523 -16 267 O ATOM 2508 NE2AGLN B 389 25.231 -66.083 26.035 0.43 29.34 N ANISOU 2508 NE2AGLN B 389 3572 3715 3862 242 -71 202 N ATOM 2509 NE2BGLN B 389 24.934 -63.194 27.422 0.57 29.80 N ANISOU 2509 NE2BGLN B 389 3529 3857 3937 38 -177 430 N ATOM 2510 H AGLN B 389 21.638 -62.641 25.451 0.43 18.98 H ATOM 2511 H BGLN B 389 21.623 -62.597 25.471 0.57 17.68 H ATOM 2512 HA AGLN B 389 21.256 -64.534 23.702 0.43 19.95 H ATOM 2513 HA BGLN B 389 21.252 -64.514 23.730 0.57 18.82 H ATOM 2514 HB2AGLN B 389 23.402 -64.311 24.474 0.43 25.04 H ATOM 2515 HB2BGLN B 389 23.096 -65.541 24.730 0.57 25.60 H ATOM 2516 HB3AGLN B 389 22.954 -64.594 25.971 0.43 25.04 H ATOM 2517 HB3BGLN B 389 23.395 -63.984 24.565 0.57 25.60 H ATOM 2518 HG2AGLN B 389 22.563 -66.811 25.475 0.43 28.39 H ATOM 2519 HG2BGLN B 389 22.610 -63.761 26.837 0.57 26.37 H ATOM 2520 HG3AGLN B 389 22.870 -66.552 23.943 0.43 28.39 H ATOM 2521 HG3BGLN B 389 22.749 -65.337 26.932 0.57 26.37 H ATOM 2522 HE21AGLN B 389 26.052 -66.285 26.192 0.43 35.23 H ATOM 2523 HE21BGLN B 389 25.748 -63.066 27.668 0.57 35.77 H ATOM 2524 HE22AGLN B 389 24.842 -65.471 26.498 0.43 35.23 H ATOM 2525 HE22BGLN B 389 24.357 -62.561 27.497 0.57 35.77 H ATOM 2526 N GLU B 390 19.750 -65.129 26.420 1.00 13.82 N ANISOU 2526 N GLU B 390 1566 2040 1646 -249 -90 19 N ATOM 2527 CA GLU B 390 18.798 -66.025 27.043 1.00 13.76 C ANISOU 2527 CA GLU B 390 1723 1820 1686 -290 -248 41 C ATOM 2528 C GLU B 390 17.472 -66.069 26.309 1.00 12.78 C ANISOU 2528 C GLU B 390 1497 1673 1685 -202 -485 -113 C ATOM 2529 O GLU B 390 16.659 -66.927 26.638 1.00 16.66 O ANISOU 2529 O GLU B 390 1975 1927 2428 85 -793 -211 O ATOM 2530 CB GLU B 390 18.600 -65.566 28.482 1.00 13.80 C ANISOU 2530 CB GLU B 390 1755 1803 1685 -135 -168 -84 C ATOM 2531 CG GLU B 390 19.871 -65.716 29.338 1.00 15.54 C ANISOU 2531 CG GLU B 390 2118 1996 1792 -256 -414 -39 C ATOM 2532 CD GLU B 390 19.609 -65.267 30.749 1.00 17.53 C ANISOU 2532 CD GLU B 390 2867 2119 1674 21 -583 86 C ATOM 2533 OE1 GLU B 390 19.245 -66.124 31.558 1.00 25.59 O ANISOU 2533 OE1 GLU B 390 5001 2429 2293 248 642 -209 O ATOM 2534 OE2 GLU B 390 19.650 -64.076 31.072 1.00 17.62 O ANISOU 2534 OE2 GLU B 390 2768 1883 2046 -96 -66 65 O ATOM 2535 H AGLU B 390 19.859 -64.385 26.838 0.43 16.60 H ATOM 2536 H BGLU B 390 19.764 -64.346 26.777 0.57 16.60 H ATOM 2537 HA GLU B 390 19.170 -66.931 27.059 1.00 16.53 H ATOM 2538 HB2 GLU B 390 18.348 -64.629 28.482 1.00 16.57 H ATOM 2539 HB3 GLU B 390 17.900 -66.097 28.890 1.00 16.57 H ATOM 2540 HG2 GLU B 390 20.141 -66.647 29.356 1.00 18.67 H ATOM 2541 HG3 GLU B 390 20.578 -65.165 28.967 1.00 18.67 H ATOM 2542 N LEU B 391 17.222 -65.112 25.397 1.00 12.47 N ANISOU 2542 N LEU B 391 1467 1686 1586 -269 -113 139 N ATOM 2543 CA LEU B 391 16.004 -65.043 24.595 1.00 12.39 C ANISOU 2543 CA LEU B 391 1390 1804 1514 -109 -239 13 C ATOM 2544 C LEU B 391 16.276 -65.523 23.149 1.00 12.92 C ANISOU 2544 C LEU B 391 1373 2347 1189 -578 20 128 C ATOM 2545 O LEU B 391 15.452 -66.186 22.543 1.00 13.66 O ANISOU 2545 O LEU B 391 1612 2216 1363 -696 -181 283 O ATOM 2546 CB LEU B 391 15.467 -63.610 24.587 1.00 12.40 C ANISOU 2546 CB LEU B 391 1450 1972 1287 -232 140 -156 C ATOM 2547 CG LEU B 391 15.076 -63.097 25.970 1.00 16.64 C ANISOU 2547 CG LEU B 391 2687 1831 1806 -467 638 -149 C ATOM 2548 CD1 LEU B 391 14.451 -61.715 25.860 1.00 19.54 C ANISOU 2548 CD1 LEU B 391 3042 2232 2151 -854 1181 -406 C ATOM 2549 CD2 LEU B 391 14.284 -63.918 26.695 1.00 20.10 C ANISOU 2549 CD2 LEU B 391 3211 2213 2213 -308 1038 -53 C ATOM 2550 H LEU B 391 17.771 -64.472 25.226 1.00 14.98 H ATOM 2551 HA LEU B 391 15.322 -65.626 24.990 1.00 14.89 H ATOM 2552 HB2 LEU B 391 16.152 -63.022 24.234 1.00 14.89 H ATOM 2553 HB3 LEU B 391 14.679 -63.575 24.023 1.00 14.89 H ATOM 2554 HG LEU B 391 15.894 -62.987 26.479 1.00 19.99 H ATOM 2555 HD11 LEU B 391 14.212 -61.410 26.739 1.00 23.46 H ATOM 2556 HD12 LEU B 391 15.087 -61.115 25.466 1.00 23.46 H ATOM 2557 HD13 LEU B 391 13.667 -61.772 25.309 1.00 23.46 H ATOM 2558 HD21 LEU B 391 14.098 -63.504 27.541 1.00 24.13 H ATOM 2559 HD22 LEU B 391 13.466 -64.066 26.215 1.00 24.13 H ATOM 2560 HD23 LEU B 391 14.740 -64.752 26.830 1.00 24.13 H ATOM 2561 N LEU B 392 17.383 -65.067 22.599 1.00 13.99 N ANISOU 2561 N LEU B 392 1411 2571 1334 -427 61 301 N ATOM 2562 CA LEU B 392 17.691 -65.342 21.186 1.00 15.21 C ANISOU 2562 CA LEU B 392 1377 2870 1531 -653 -59 278 C ATOM 2563 C LEU B 392 17.622 -66.855 20.952 1.00 16.07 C ANISOU 2563 C LEU B 392 1896 3026 1183 -965 7 116 C ATOM 2564 O LEU B 392 18.271 -67.657 21.660 1.00 19.20 O ANISOU 2564 O LEU B 392 2199 3068 2029 -1125 -489 258 O ATOM 2565 CB LEU B 392 19.096 -64.829 20.860 1.00 16.03 C ANISOU 2565 CB LEU B 392 1829 2838 1423 -398 30 -58 C ATOM 2566 CG LEU B 392 19.095 -63.371 20.616 1.00 20.78 C ANISOU 2566 CG LEU B 392 2168 3045 2684 100 482 -72 C ATOM 2567 CD1 LEU B 392 20.556 -62.948 20.675 1.00 26.25 C ANISOU 2567 CD1 LEU B 392 2881 3400 3691 899 -90 -488 C ATOM 2568 CD2 LEU B 392 18.466 -63.040 19.233 1.00 21.52 C ANISOU 2568 CD2 LEU B 392 2246 2905 3026 -361 -790 -278 C ATOM 2569 H LEU B 392 17.976 -64.597 23.007 1.00 16.81 H ATOM 2570 HA LEU B 392 17.041 -64.895 20.604 1.00 18.26 H ATOM 2571 HB2 LEU B 392 19.685 -65.011 21.608 1.00 19.25 H ATOM 2572 HB3 LEU B 392 19.421 -65.270 20.060 1.00 19.25 H ATOM 2573 HG LEU B 392 18.600 -62.913 21.313 1.00 24.95 H ATOM 2574 HD11 LEU B 392 20.613 -62.001 20.521 1.00 31.51 H ATOM 2575 HD12 LEU B 392 20.908 -63.161 21.542 1.00 31.51 H ATOM 2576 HD13 LEU B 392 21.046 -63.419 19.997 1.00 31.51 H ATOM 2577 HD21 LEU B 392 18.480 -62.090 19.103 1.00 25.84 H ATOM 2578 HD22 LEU B 392 18.978 -63.472 18.545 1.00 25.84 H ATOM 2579 HD23 LEU B 392 17.561 -63.360 19.217 1.00 25.84 H ATOM 2580 N GLY B 393 16.939 -67.246 19.871 1.00 15.70 N ANISOU 2580 N GLY B 393 1931 2635 1397 -1067 31 348 N ATOM 2581 CA GLY B 393 16.785 -68.629 19.499 1.00 16.42 C ANISOU 2581 CA GLY B 393 2058 2497 1683 -1002 182 91 C ATOM 2582 C GLY B 393 15.646 -69.430 20.152 1.00 16.03 C ANISOU 2582 C GLY B 393 2063 2286 1742 -1290 134 6 C ATOM 2583 O GLY B 393 15.379 -70.553 19.797 1.00 18.56 O ANISOU 2583 O GLY B 393 2698 2363 1991 -1150 326 302 O ATOM 2584 H GLY B 393 16.551 -66.701 19.331 1.00 18.85 H ATOM 2585 HA2 GLY B 393 16.652 -68.670 18.539 1.00 19.72 H ATOM 2586 HA3 GLY B 393 17.613 -69.091 19.699 1.00 19.72 H ATOM 2587 N LYS B 394 15.017 -68.820 21.132 1.00 15.01 N ANISOU 2587 N LYS B 394 1962 2204 1539 -1179 152 20 N ATOM 2588 CA LYS B 394 13.851 -69.353 21.772 1.00 14.06 C ANISOU 2588 CA LYS B 394 1894 1907 1542 -872 141 -25 C ATOM 2589 C LYS B 394 12.600 -68.791 21.180 1.00 11.70 C ANISOU 2589 C LYS B 394 1773 1365 1309 -546 -21 190 C ATOM 2590 O LYS B 394 12.589 -67.673 20.713 1.00 12.18 O ANISOU 2590 O LYS B 394 2061 1095 1474 -435 -147 -34 O ATOM 2591 CB LYS B 394 13.903 -69.068 23.268 1.00 15.85 C ANISOU 2591 CB LYS B 394 2384 2151 1489 -839 -337 -244 C ATOM 2592 CG LYS B 394 14.801 -70.126 23.963 1.00 22.12 C ANISOU 2592 CG LYS B 394 2924 2928 2552 -750 -340 416 C ATOM 2593 CD LYS B 394 14.828 -69.930 25.467 1.00 25.21 C ANISOU 2593 CD LYS B 394 3332 3464 2781 -757 -1228 -112 C ATOM 2594 CE LYS B 394 15.709 -70.953 26.071 1.00 29.63 C ANISOU 2594 CE LYS B 394 3703 3652 3903 -9 -465 -348 C ATOM 2595 NZ LYS B 394 14.762 -72.046 26.428 1.00 27.59 N ANISOU 2595 NZ LYS B 394 4124 3005 3355 744 -650 -1173 N ATOM 2596 H LYS B 394 15.263 -68.061 21.454 1.00 18.03 H ATOM 2597 HA LYS B 394 13.835 -70.326 21.650 1.00 16.89 H ATOM 2598 HB2 LYS B 394 14.283 -68.189 23.420 1.00 19.04 H ATOM 2599 HB3 LYS B 394 13.010 -69.123 23.642 1.00 19.04 H ATOM 2600 HG2 LYS B 394 14.453 -71.011 23.779 1.00 26.56 H ATOM 2601 HG3 LYS B 394 15.708 -70.044 23.630 1.00 26.56 H ATOM 2602 HD2 LYS B 394 15.181 -69.050 25.677 1.00 30.26 H ATOM 2603 HD3 LYS B 394 13.934 -70.035 25.828 1.00 30.26 H ATOM 2604 HE2 LYS B 394 16.356 -71.275 25.426 1.00 35.57 H ATOM 2605 HE3 LYS B 394 16.134 -70.611 26.874 1.00 35.57 H ATOM 2606 HZ1 LYS B 394 14.103 -71.721 27.046 1.00 33.13 H ATOM 2607 HZ2 LYS B 394 14.319 -72.367 25.639 1.00 33.13 H ATOM 2608 HZ3 LYS B 394 15.240 -72.772 26.835 1.00 33.13 H ATOM 2609 N ASN B 395 11.525 -69.552 21.208 1.00 12.24 N ANISOU 2609 N ASN B 395 1774 1420 1458 -486 130 -277 N ATOM 2610 CA ASN B 395 10.253 -69.046 20.855 1.00 11.13 C ANISOU 2610 CA ASN B 395 1889 1223 1118 -195 237 -246 C ATOM 2611 C ASN B 395 9.699 -68.179 21.952 1.00 9.51 C ANISOU 2611 C ASN B 395 1539 1099 975 -216 187 -218 C ATOM 2612 O ASN B 395 9.786 -68.495 23.125 1.00 10.62 O ANISOU 2612 O ASN B 395 1646 1421 967 -307 185 -256 O ATOM 2613 CB ASN B 395 9.293 -70.193 20.567 1.00 12.97 C ANISOU 2613 CB ASN B 395 2282 1304 1344 -165 103 -176 C ATOM 2614 CG ASN B 395 8.118 -69.740 19.705 1.00 14.05 C ANISOU 2614 CG ASN B 395 2734 1266 1341 190 166 -92 C ATOM 2615 OD1 ASN B 395 7.330 -68.874 20.079 1.00 14.91 O ANISOU 2615 OD1 ASN B 395 2724 1770 1169 -247 73 -16 O ATOM 2616 ND2 ASN B 395 8.078 -70.258 18.471 1.00 16.28 N ANISOU 2616 ND2 ASN B 395 2942 1655 1588 89 -298 353 N ATOM 2617 H ASN B 395 11.522 -70.380 21.436 1.00 14.71 H ATOM 2618 HA ASN B 395 10.334 -68.503 20.044 1.00 13.37 H ATOM 2619 HB2 ASN B 395 9.765 -70.894 20.092 1.00 15.58 H ATOM 2620 HB3 ASN B 395 8.941 -70.534 21.404 1.00 15.58 H ATOM 2621 HD21 ASN B 395 7.352 -70.014 17.860 1.00 19.55 H ATOM 2622 HD22 ASN B 395 8.775 -70.883 18.179 1.00 19.55 H ATOM 2623 N ILE B 396 9.082 -67.048 21.596 1.00 10.06 N ANISOU 2623 N ILE B 396 1583 1104 1135 -214 305 -205 N ATOM 2624 CA ILE B 396 8.398 -66.211 22.578 1.00 9.55 C ANISOU 2624 CA ILE B 396 1411 993 1225 -82 222 -140 C ATOM 2625 C ILE B 396 7.418 -66.989 23.390 1.00 8.59 C ANISOU 2625 C ILE B 396 1329 952 985 -128 -13 -207 C ATOM 2626 O ILE B 396 7.210 -66.686 24.590 1.00 9.46 O ANISOU 2626 O ILE B 396 1580 1007 1006 66 67 -17 O ATOM 2627 CB ILE B 396 7.776 -64.948 21.871 1.00 11.39 C ANISOU 2627 CB ILE B 396 1683 1087 1559 -228 520 -256 C ATOM 2628 CG1 ILE B 396 7.381 -63.883 22.896 1.00 13.45 C ANISOU 2628 CG1 ILE B 396 2041 1229 1842 -330 441 -133 C ATOM 2629 CG2 ILE B 396 6.680 -65.365 20.936 1.00 13.65 C ANISOU 2629 CG2 ILE B 396 2051 1540 1594 -313 167 -572 C ATOM 2630 CD1 ILE B 396 6.970 -62.533 22.257 1.00 17.04 C ANISOU 2630 CD1 ILE B 396 2566 1399 2509 -483 1473 -396 C ATOM 2631 H ILE B 396 9.046 -66.746 20.791 1.00 12.08 H ATOM 2632 HA ILE B 396 9.074 -65.876 23.204 1.00 11.48 H ATOM 2633 HB ILE B 396 8.477 -64.559 21.324 1.00 13.68 H ATOM 2634 HG12 ILE B 396 6.628 -64.210 23.413 1.00 16.16 H ATOM 2635 HG13 ILE B 396 8.136 -63.717 23.482 1.00 16.16 H ATOM 2636 HG21 ILE B 396 6.314 -64.582 20.515 1.00 16.39 H ATOM 2637 HG22 ILE B 396 7.044 -65.954 20.271 1.00 16.39 H ATOM 2638 HG23 ILE B 396 5.997 -65.817 21.437 1.00 16.39 H ATOM 2639 HD11 ILE B 396 6.736 -61.916 22.955 1.00 20.46 H ATOM 2640 HD12 ILE B 396 7.709 -62.188 21.750 1.00 20.46 H ATOM 2641 HD13 ILE B 396 6.215 -62.676 21.681 1.00 20.46 H ATOM 2642 N VAL B 397 6.795 -68.010 22.820 1.00 9.13 N ANISOU 2642 N VAL B 397 1554 1001 915 -97 54 -12 N ATOM 2643 CA VAL B 397 5.813 -68.790 23.550 1.00 9.58 C ANISOU 2643 CA VAL B 397 1364 1088 1188 86 -60 23 C ATOM 2644 C VAL B 397 6.407 -69.519 24.736 1.00 8.34 C ANISOU 2644 C VAL B 397 1369 905 896 15 33 69 C ATOM 2645 O VAL B 397 5.657 -69.814 25.685 1.00 9.87 O ANISOU 2645 O VAL B 397 1607 1108 1035 200 153 -6 O ATOM 2646 CB VAL B 397 5.004 -69.694 22.575 1.00 11.36 C ANISOU 2646 CB VAL B 397 1608 1419 1289 3 -41 187 C ATOM 2647 CG1 VAL B 397 3.944 -70.498 23.249 1.00 16.11 C ANISOU 2647 CG1 VAL B 397 2232 2018 1873 703 -230 313 C ATOM 2648 CG2 VAL B 397 4.340 -68.844 21.508 1.00 16.09 C ANISOU 2648 CG2 VAL B 397 2350 1950 1812 -143 -648 252 C ATOM 2649 H VAL B 397 6.924 -68.272 22.011 1.00 10.98 H ATOM 2650 HA VAL B 397 5.167 -68.154 23.924 1.00 11.51 H ATOM 2651 HB VAL B 397 5.618 -70.314 22.130 1.00 13.65 H ATOM 2652 HG11 VAL B 397 3.488 -71.028 22.590 1.00 19.35 H ATOM 2653 HG12 VAL B 397 4.353 -71.069 23.903 1.00 19.35 H ATOM 2654 HG13 VAL B 397 3.324 -69.903 23.676 1.00 19.35 H ATOM 2655 HG21 VAL B 397 3.846 -69.415 20.916 1.00 19.32 H ATOM 2656 HG22 VAL B 397 3.747 -68.219 21.931 1.00 19.32 H ATOM 2657 HG23 VAL B 397 5.018 -68.371 21.018 1.00 19.32 H ATOM 2658 N AGLU B 398 7.712 -69.778 24.700 0.51 9.10 N ANISOU 2658 N AGLU B 398 1474 992 993 -93 -17 113 N ATOM 2659 N BGLU B 398 7.698 -69.826 24.715 0.49 8.75 N ANISOU 2659 N BGLU B 398 1482 983 859 28 57 -84 N ATOM 2660 CA AGLU B 398 8.408 -70.417 25.833 0.51 10.10 C ANISOU 2660 CA AGLU B 398 1787 1084 966 -90 -76 70 C ATOM 2661 CA BGLU B 398 8.361 -70.427 25.887 0.49 9.96 C ANISOU 2661 CA BGLU B 398 1820 1183 782 5 -41 -34 C ATOM 2662 C AGLU B 398 8.473 -69.555 27.069 0.51 8.33 C ANISOU 2662 C AGLU B 398 1678 1015 473 61 57 -15 C ATOM 2663 C BGLU B 398 8.235 -69.585 27.132 0.49 10.31 C ANISOU 2663 C BGLU B 398 1625 1077 1215 348 -64 -279 C ATOM 2664 O AGLU B 398 8.791 -70.059 28.136 0.51 10.32 O ANISOU 2664 O AGLU B 398 2334 1056 530 -243 -91 -72 O ATOM 2665 O BGLU B 398 8.241 -70.117 28.246 0.49 9.64 O ANISOU 2665 O BGLU B 398 1288 1090 1285 286 0 -34 O ATOM 2666 CB AGLU B 398 9.836 -70.854 25.422 0.51 10.95 C ANISOU 2666 CB AGLU B 398 1806 1086 1268 -444 -10 196 C ATOM 2667 CB BGLU B 398 9.856 -70.647 25.581 0.49 11.10 C ANISOU 2667 CB BGLU B 398 1902 1326 992 -130 112 93 C ATOM 2668 CG AGLU B 398 9.856 -71.925 24.319 0.51 10.20 C ANISOU 2668 CG AGLU B 398 1787 998 1089 -381 -150 190 C ATOM 2669 CG BGLU B 398 10.161 -71.731 24.619 0.49 13.16 C ANISOU 2669 CG BGLU B 398 1659 1677 1665 124 378 -724 C ATOM 2670 CD AGLU B 398 11.286 -72.163 23.840 0.51 10.30 C ANISOU 2670 CD AGLU B 398 2184 954 775 -582 293 -119 C ATOM 2671 CD BGLU B 398 11.587 -72.148 24.822 0.49 16.00 C ANISOU 2671 CD BGLU B 398 2027 1542 2509 100 -278 -140 C ATOM 2672 OE1AGLU B 398 12.196 -72.419 24.600 0.51 16.97 O ANISOU 2672 OE1AGLU B 398 2675 2438 1333 -746 564 -56 O ATOM 2673 OE1BGLU B 398 12.239 -71.572 25.767 0.49 20.90 O ANISOU 2673 OE1BGLU B 398 2819 1507 3615 449 293 -294 O ATOM 2674 OE2AGLU B 398 11.555 -71.995 22.666 0.51 18.20 O ANISOU 2674 OE2AGLU B 398 3175 1677 2063 -1422 991 -874 O ATOM 2675 OE2BGLU B 398 12.057 -73.071 24.118 0.49 16.85 O ANISOU 2675 OE2BGLU B 398 2296 1505 2603 293 198 380 O ATOM 2676 H AGLU B 398 8.224 -69.597 24.033 0.51 10.94 H ATOM 2677 H BGLU B 398 8.218 -69.698 24.042 0.49 10.51 H ATOM 2678 HA AGLU B 398 7.915 -71.228 26.074 0.51 12.13 H ATOM 2679 HA BGLU B 398 7.956 -71.302 26.070 0.49 11.97 H ATOM 2680 HB2AGLU B 398 10.319 -70.079 25.094 0.51 13.15 H ATOM 2681 HB2BGLU B 398 10.219 -69.825 25.216 0.49 13.34 H ATOM 2682 HB3AGLU B 398 10.288 -71.218 26.199 0.51 13.15 H ATOM 2683 HB3BGLU B 398 10.311 -70.860 26.411 0.49 13.34 H ATOM 2684 HG2AGLU B 398 9.506 -72.758 24.670 0.51 12.25 H ATOM 2685 HG2BGLU B 398 9.584 -72.493 24.785 0.49 15.81 H ATOM 2686 HG3AGLU B 398 9.325 -71.624 23.566 0.51 12.25 H ATOM 2687 HG3BGLU B 398 10.054 -71.407 23.711 0.49 15.81 H ATOM 2688 N PHE B 399 8.138 -68.275 26.956 1.00 8.50 N ANISOU 2688 N PHE B 399 1340 993 897 84 27 22 N ATOM 2689 CA PHE B 399 8.098 -67.316 28.058 1.00 8.42 C ANISOU 2689 CA PHE B 399 1147 990 1062 55 64 -19 C ATOM 2690 C PHE B 399 6.695 -66.952 28.433 1.00 8.08 C ANISOU 2690 C PHE B 399 984 1018 1067 67 -110 -11 C ATOM 2691 O PHE B 399 6.518 -66.127 29.322 1.00 9.73 O ANISOU 2691 O PHE B 399 1306 1279 1111 101 66 379 O ATOM 2692 CB PHE B 399 8.886 -66.049 27.666 1.00 9.64 C ANISOU 2692 CB PHE B 399 1305 1105 1255 200 236 -23 C ATOM 2693 CG PHE B 399 10.321 -66.326 27.401 1.00 9.29 C ANISOU 2693 CG PHE B 399 1288 1241 1001 294 -7 -66 C ATOM 2694 CD1 PHE B 399 10.776 -66.701 26.123 1.00 9.98 C ANISOU 2694 CD1 PHE B 399 1386 1348 1057 277 52 -100 C ATOM 2695 CD2 PHE B 399 11.240 -66.317 28.429 1.00 10.59 C ANISOU 2695 CD2 PHE B 399 1304 1427 1292 155 235 192 C ATOM 2696 CE1 PHE B 399 12.086 -67.013 25.915 1.00 12.19 C ANISOU 2696 CE1 PHE B 399 1173 1954 1506 253 199 297 C ATOM 2697 CE2 PHE B 399 12.553 -66.636 28.235 1.00 12.73 C ANISOU 2697 CE2 PHE B 399 1385 2042 1409 353 201 324 C ATOM 2698 CZ PHE B 399 12.989 -66.998 26.966 1.00 13.46 C ANISOU 2698 CZ PHE B 399 993 1990 2131 63 -18 173 C ATOM 2699 H APHE B 399 7.916 -67.919 26.205 0.51 10.22 H ATOM 2700 H BPHE B 399 8.092 -67.903 26.182 0.49 10.22 H ATOM 2701 HA PHE B 399 8.530 -67.713 28.843 1.00 10.12 H ATOM 2702 HB2 PHE B 399 8.499 -65.672 26.860 1.00 11.59 H ATOM 2703 HB3 PHE B 399 8.832 -65.406 28.391 1.00 11.59 H ATOM 2704 HD1 PHE B 399 10.176 -66.736 25.413 1.00 11.99 H ATOM 2705 HD2 PHE B 399 10.952 -66.099 29.285 1.00 12.72 H ATOM 2706 HE1 PHE B 399 12.375 -67.246 25.062 1.00 14.65 H ATOM 2707 HE2 PHE B 399 13.153 -66.606 28.946 1.00 15.29 H ATOM 2708 HZ PHE B 399 13.887 -67.188 26.815 1.00 16.17 H ATOM 2709 N CYS B 400 5.689 -67.528 27.764 1.00 8.56 N ANISOU 2709 N CYS B 400 1112 1058 1081 25 34 55 N ATOM 2710 CA CYS B 400 4.316 -67.101 27.924 1.00 8.33 C ANISOU 2710 CA CYS B 400 1141 993 1032 88 35 15 C ATOM 2711 C CYS B 400 3.542 -67.995 28.850 1.00 8.35 C ANISOU 2711 C CYS B 400 1258 936 980 24 -93 -30 C ATOM 2712 O CYS B 400 3.679 -69.212 28.848 1.00 9.57 O ANISOU 2712 O CYS B 400 1425 953 1256 62 -13 -49 O ATOM 2713 CB CYS B 400 3.676 -67.115 26.518 1.00 9.56 C ANISOU 2713 CB CYS B 400 1335 1242 1057 211 -48 -300 C ATOM 2714 SG CYS B 400 2.004 -66.555 26.423 1.00 10.33 S ANISOU 2714 SG CYS B 400 1446 1150 1328 64 -127 -129 S ATOM 2715 H CYS B 400 5.789 -68.174 27.206 1.00 10.28 H ATOM 2716 HA CYS B 400 4.291 -66.185 28.273 1.00 10.01 H ATOM 2717 HB2 CYS B 400 4.205 -66.548 25.936 1.00 11.49 H ATOM 2718 HB3 CYS B 400 3.695 -68.026 26.184 1.00 11.49 H ATOM 2719 HG CYS B 400 1.945 -65.287 26.853 1.00 12.41 H ATOM 2720 N HIS B 401 2.689 -67.397 29.648 1.00 8.88 N ANISOU 2720 N HIS B 401 1331 942 1102 161 159 -23 N ATOM 2721 CA HIS B 401 1.826 -68.115 30.552 1.00 8.84 C ANISOU 2721 CA HIS B 401 1149 1012 1197 169 -216 -16 C ATOM 2722 C HIS B 401 1.002 -69.139 29.772 1.00 9.19 C ANISOU 2722 C HIS B 401 1101 1149 1242 67 79 -268 C ATOM 2723 O HIS B 401 0.496 -68.862 28.701 1.00 9.69 O ANISOU 2723 O HIS B 401 1466 1099 1116 27 -225 -182 O ATOM 2724 CB HIS B 401 0.898 -67.132 31.253 1.00 9.66 C ANISOU 2724 CB HIS B 401 1259 1237 1173 -17 28 -11 C ATOM 2725 CG HIS B 401 0.112 -67.633 32.390 1.00 10.24 C ANISOU 2725 CG HIS B 401 1239 1368 1286 167 -34 -81 C ATOM 2726 ND1 HIS B 401 -0.940 -68.526 32.248 1.00 11.89 N ANISOU 2726 ND1 HIS B 401 1620 1474 1425 310 -7 -267 N ATOM 2727 CD2 HIS B 401 0.243 -67.358 33.693 1.00 11.53 C ANISOU 2727 CD2 HIS B 401 1551 1661 1169 90 -10 -160 C ATOM 2728 CE1 HIS B 401 -1.407 -68.785 33.438 1.00 13.39 C ANISOU 2728 CE1 HIS B 401 1878 1946 1264 560 117 -272 C ATOM 2729 NE2 HIS B 401 -0.703 -68.114 34.347 1.00 13.87 N ANISOU 2729 NE2 HIS B 401 1766 2045 1460 364 264 -249 N ATOM 2730 H HIS B 401 2.588 -66.543 29.685 1.00 10.67 H ATOM 2731 HA HIS B 401 2.362 -68.583 31.226 1.00 10.62 H ATOM 2732 HB2 HIS B 401 1.436 -66.394 31.582 1.00 11.60 H ATOM 2733 HB3 HIS B 401 0.267 -66.797 30.598 1.00 11.60 H ATOM 2734 HD2 HIS B 401 0.878 -66.802 34.084 1.00 13.85 H ATOM 2735 HE1 HIS B 401 -2.117 -69.356 33.624 1.00 16.08 H ATOM 2736 N PRO B 402 0.809 -70.335 30.371 1.00 10.41 N ANISOU 2736 N PRO B 402 1423 1180 1353 183 -406 -321 N ATOM 2737 CA PRO B 402 0.042 -71.376 29.670 1.00 10.99 C ANISOU 2737 CA PRO B 402 1531 1169 1475 326 -529 -291 C ATOM 2738 C PRO B 402 -1.300 -70.914 29.165 1.00 11.57 C ANISOU 2738 C PRO B 402 1622 1220 1555 420 -505 -237 C ATOM 2739 O PRO B 402 -1.734 -71.356 28.111 1.00 13.37 O ANISOU 2739 O PRO B 402 2059 1201 1819 315 -816 -211 O ATOM 2740 CB PRO B 402 -0.076 -72.478 30.756 1.00 14.78 C ANISOU 2740 CB PRO B 402 1795 1324 2496 350 -706 -599 C ATOM 2741 CG PRO B 402 1.022 -72.311 31.620 1.00 18.20 C ANISOU 2741 CG PRO B 402 2566 1797 2551 769 -924 -984 C ATOM 2742 CD PRO B 402 1.372 -70.843 31.646 1.00 12.28 C ANISOU 2742 CD PRO B 402 1676 1295 1694 137 -454 -352 C ATOM 2743 HA PRO B 402 0.563 -71.727 28.917 1.00 13.20 H ATOM 2744 HB2 PRO B 402 -0.908 -72.364 31.240 1.00 17.75 H ATOM 2745 HB3 PRO B 402 -0.045 -73.350 30.334 1.00 17.75 H ATOM 2746 HG2 PRO B 402 0.776 -72.612 32.509 1.00 21.85 H ATOM 2747 HG3 PRO B 402 1.771 -72.829 31.287 1.00 21.85 H ATOM 2748 HD2 PRO B 402 0.948 -70.406 32.401 1.00 14.75 H ATOM 2749 HD3 PRO B 402 2.335 -70.725 31.661 1.00 14.75 H ATOM 2750 N GLU B 403 -2.014 -70.093 29.923 1.00 11.31 N ANISOU 2750 N GLU B 403 1408 1328 1562 345 -410 -393 N ATOM 2751 CA GLU B 403 -3.344 -69.648 29.496 1.00 12.73 C ANISOU 2751 CA GLU B 403 1601 1415 1822 343 -342 -421 C ATOM 2752 C GLU B 403 -3.304 -68.755 28.263 1.00 11.72 C ANISOU 2752 C GLU B 403 1722 1210 1521 470 -329 -415 C ATOM 2753 O GLU B 403 -4.302 -68.666 27.545 1.00 13.86 O ANISOU 2753 O GLU B 403 1662 1743 1860 397 -613 -507 O ATOM 2754 CB GLU B 403 -4.051 -68.898 30.602 1.00 14.29 C ANISOU 2754 CB GLU B 403 1772 1915 1744 224 -192 -427 C ATOM 2755 CG GLU B 403 -4.513 -69.724 31.761 1.00 18.38 C ANISOU 2755 CG GLU B 403 2054 2538 2393 356 -337 -791 C ATOM 2756 CD GLU B 403 -4.943 -68.844 32.946 1.00 20.06 C ANISOU 2756 CD GLU B 403 2469 2448 2706 216 242 -739 C ATOM 2757 OE1 GLU B 403 -5.332 -67.632 32.761 1.00 20.03 O ANISOU 2757 OE1 GLU B 403 2420 2803 2389 365 390 -720 O ATOM 2758 OE2 GLU B 403 -4.965 -69.394 34.065 1.00 24.87 O ANISOU 2758 OE2 GLU B 403 3466 3210 2773 285 601 -943 O ATOM 2759 H GLU B 403 -1.758 -69.778 30.681 1.00 13.59 H ATOM 2760 HA GLU B 403 -3.884 -70.436 29.276 1.00 15.29 H ATOM 2761 HB2 GLU B 403 -3.446 -68.225 30.949 1.00 17.17 H ATOM 2762 HB3 GLU B 403 -4.833 -68.466 30.225 1.00 17.17 H ATOM 2763 HG2 GLU B 403 -5.275 -70.260 31.489 1.00 22.08 H ATOM 2764 HG3 GLU B 403 -3.788 -70.296 32.055 1.00 22.08 H ATOM 2765 N ASP B 404 -2.206 -68.072 28.030 1.00 9.95 N ANISOU 2765 N ASP B 404 1302 1120 1360 220 -178 -379 N ATOM 2766 CA ASP B 404 -2.069 -67.096 26.966 1.00 9.83 C ANISOU 2766 CA ASP B 404 1308 1028 1401 192 -375 -150 C ATOM 2767 C ASP B 404 -1.303 -67.629 25.759 1.00 9.28 C ANISOU 2767 C ASP B 404 1380 974 1172 -29 -482 -71 C ATOM 2768 O ASP B 404 -1.233 -66.962 24.728 1.00 10.00 O ANISOU 2768 O ASP B 404 1656 1004 1139 -26 -333 -85 O ATOM 2769 CB ASP B 404 -1.321 -65.844 27.464 1.00 9.95 C ANISOU 2769 CB ASP B 404 1308 1135 1337 202 185 -93 C ATOM 2770 CG ASP B 404 -1.981 -65.139 28.622 1.00 10.44 C ANISOU 2770 CG ASP B 404 1229 1323 1416 326 -102 -194 C ATOM 2771 OD1 ASP B 404 -3.218 -65.197 28.762 1.00 12.16 O ANISOU 2771 OD1 ASP B 404 1378 1516 1726 276 -179 79 O ATOM 2772 OD2 ASP B 404 -1.229 -64.510 29.417 1.00 10.69 O ANISOU 2772 OD2 ASP B 404 1359 1468 1235 306 55 -68 O ATOM 2773 H ASP B 404 -1.489 -68.158 28.498 1.00 11.96 H ATOM 2774 HA ASP B 404 -2.960 -66.819 26.666 1.00 11.82 H ATOM 2775 HB2 ASP B 404 -0.432 -66.108 27.748 1.00 11.95 H ATOM 2776 HB3 ASP B 404 -1.255 -65.212 26.732 1.00 11.95 H ATOM 2777 N AGLN B 405 -0.722 -68.829 25.866 0.55 10.11 N ANISOU 2777 N AGLN B 405 1509 941 1394 -1 -345 13 N ATOM 2778 N BGLN B 405 -0.784 -68.843 25.854 0.45 9.73 N ANISOU 2778 N BGLN B 405 1509 952 1235 78 -437 -30 N ATOM 2779 CA AGLN B 405 0.129 -69.335 24.792 0.55 9.97 C ANISOU 2779 CA AGLN B 405 1359 1103 1327 -71 -476 -178 C ATOM 2780 CA BGLN B 405 0.102 -69.335 24.822 0.45 9.89 C ANISOU 2780 CA BGLN B 405 1378 1081 1297 -35 -431 -224 C ATOM 2781 C AGLN B 405 -0.590 -69.412 23.456 0.55 9.98 C ANISOU 2781 C AGLN B 405 1546 964 1281 -195 -519 -28 C ATOM 2782 C BGLN B 405 -0.578 -69.457 23.465 0.45 10.06 C ANISOU 2782 C BGLN B 405 1516 990 1316 -179 -483 -99 C ATOM 2783 O AGLN B 405 -0.035 -69.019 22.445 0.55 10.62 O ANISOU 2783 O AGLN B 405 1559 1105 1371 -227 -390 37 O ATOM 2784 O BGLN B 405 0.009 -69.127 22.457 0.45 10.61 O ANISOU 2784 O BGLN B 405 1489 1163 1380 -149 -358 5 O ATOM 2785 CB AGLN B 405 0.751 -70.700 25.087 0.55 10.10 C ANISOU 2785 CB AGLN B 405 1366 1125 1345 -281 -457 -65 C ATOM 2786 CB BGLN B 405 0.715 -70.662 25.217 0.45 10.69 C ANISOU 2786 CB BGLN B 405 1327 1088 1648 -65 -246 -124 C ATOM 2787 CG AGLN B 405 1.956 -70.604 26.054 0.55 8.67 C ANISOU 2787 CG AGLN B 405 1275 1081 938 -487 -290 -47 C ATOM 2788 CG BGLN B 405 1.687 -70.523 26.390 0.45 9.74 C ANISOU 2788 CG BGLN B 405 1105 1176 1421 101 -330 -62 C ATOM 2789 CD AGLN B 405 2.432 -71.978 26.510 0.55 9.69 C ANISOU 2789 CD AGLN B 405 856 1173 1652 -374 -270 290 C ATOM 2790 CD BGLN B 405 2.276 -71.847 26.770 0.45 9.34 C ANISOU 2790 CD BGLN B 405 1106 1110 1331 64 -156 -171 C ATOM 2791 OE1AGLN B 405 2.048 -73.026 25.971 0.55 10.04 O ANISOU 2791 OE1AGLN B 405 1287 1227 1302 -359 -416 318 O ATOM 2792 OE1BGLN B 405 1.547 -72.832 26.855 0.45 12.05 O ANISOU 2792 OE1BGLN B 405 1176 1326 2074 182 -80 -244 O ATOM 2793 NE2AGLN B 405 3.258 -71.985 27.528 0.55 7.37 N ANISOU 2793 NE2AGLN B 405 855 913 1031 -28 -120 38 N ATOM 2794 NE2BGLN B 405 3.579 -71.898 26.981 0.45 8.87 N ANISOU 2794 NE2BGLN B 405 1229 975 1167 -217 289 -157 N ATOM 2795 H AGLN B 405 -0.804 -69.357 26.539 0.55 12.15 H ATOM 2796 H BGLN B 405 -0.929 -69.394 26.498 0.45 11.69 H ATOM 2797 HA AGLN B 405 0.871 -68.706 24.678 0.55 11.98 H ATOM 2798 HA BGLN B 405 0.837 -68.695 24.720 0.45 11.88 H ATOM 2799 HB2AGLN B 405 0.083 -71.271 25.496 0.55 12.13 H ATOM 2800 HB2BGLN B 405 0.009 -71.272 25.481 0.45 12.85 H ATOM 2801 HB3AGLN B 405 1.063 -71.093 24.257 0.55 12.13 H ATOM 2802 HB3BGLN B 405 1.204 -71.023 24.461 0.45 12.85 H ATOM 2803 HG2AGLN B 405 2.693 -70.162 25.602 0.55 10.42 H ATOM 2804 HG2BGLN B 405 2.410 -69.928 26.138 0.45 11.70 H ATOM 2805 HG3AGLN B 405 1.695 -70.099 26.839 0.55 10.42 H ATOM 2806 HG3BGLN B 405 1.213 -70.168 27.158 0.45 11.70 H ATOM 2807 HE21AGLN B 405 3.561 -72.731 27.830 0.55 8.85 H ATOM 2808 HE21BGLN B 405 3.951 -72.641 27.201 0.45 10.66 H ATOM 2809 HE22AGLN B 405 3.496 -71.244 27.893 0.55 8.85 H ATOM 2810 HE22BGLN B 405 4.056 -71.186 26.899 0.45 10.66 H ATOM 2811 N GLN B 406 -1.810 -69.974 23.427 1.00 10.84 N ANISOU 2811 N GLN B 406 1501 1146 1473 48 -467 -104 N ATOM 2812 CA GLN B 406 -2.467 -70.163 22.173 1.00 10.67 C ANISOU 2812 CA GLN B 406 1554 1099 1403 90 -488 -68 C ATOM 2813 C GLN B 406 -2.824 -68.819 21.555 1.00 9.98 C ANISOU 2813 C GLN B 406 1395 1087 1308 -25 -429 36 C ATOM 2814 O GLN B 406 -2.687 -68.623 20.355 1.00 10.48 O ANISOU 2814 O GLN B 406 1393 1261 1327 -128 -406 9 O ATOM 2815 CB GLN B 406 -3.690 -71.062 22.314 1.00 13.60 C ANISOU 2815 CB GLN B 406 2010 1285 1871 304 -733 -131 C ATOM 2816 CG GLN B 406 -4.254 -71.527 20.920 1.00 14.62 C ANISOU 2816 CG GLN B 406 1930 1505 2120 190 -688 92 C ATOM 2817 CD GLN B 406 -3.201 -72.240 20.086 1.00 15.33 C ANISOU 2817 CD GLN B 406 2124 1457 2246 50 -710 42 C ATOM 2818 OE1 GLN B 406 -2.490 -73.121 20.539 1.00 18.04 O ANISOU 2818 OE1 GLN B 406 2566 1652 2638 -90 -887 125 O ATOM 2819 NE2 GLN B 406 -3.157 -71.884 18.842 1.00 16.59 N ANISOU 2819 NE2 GLN B 406 2305 1835 2161 -146 -400 409 N ATOM 2820 H AGLN B 406 -2.253 -70.240 24.115 0.55 13.03 H ATOM 2821 H BGLN B 406 -2.268 -70.213 24.115 0.45 13.03 H ATOM 2822 HA GLN B 406 -1.844 -70.611 21.563 1.00 12.82 H ATOM 2823 HB2 GLN B 406 -3.446 -71.852 22.820 1.00 16.33 H ATOM 2824 HB3 GLN B 406 -4.390 -70.575 22.774 1.00 16.33 H ATOM 2825 HG2 GLN B 406 -4.991 -72.141 21.064 1.00 17.56 H ATOM 2826 HG3 GLN B 406 -4.557 -70.751 20.424 1.00 17.56 H ATOM 2827 HE21 GLN B 406 -2.586 -72.246 18.311 1.00 19.92 H ATOM 2828 HE22 GLN B 406 -3.700 -71.287 18.546 1.00 19.92 H ATOM 2829 N LEU B 407 -3.263 -67.862 22.361 1.00 9.81 N ANISOU 2829 N LEU B 407 1358 1044 1326 -42 -313 -170 N ATOM 2830 CA LEU B 407 -3.505 -66.508 21.891 1.00 9.55 C ANISOU 2830 CA LEU B 407 1283 1118 1229 31 -308 87 C ATOM 2831 C LEU B 407 -2.274 -65.944 21.219 1.00 9.48 C ANISOU 2831 C LEU B 407 1252 998 1351 -186 -488 -25 C ATOM 2832 O LEU B 407 -2.310 -65.279 20.166 1.00 9.71 O ANISOU 2832 O LEU B 407 1306 1100 1282 -159 -208 -39 O ATOM 2833 CB LEU B 407 -3.978 -65.620 23.025 1.00 10.67 C ANISOU 2833 CB LEU B 407 1331 1391 1332 107 -78 -12 C ATOM 2834 CG LEU B 407 -4.277 -64.148 22.651 1.00 12.43 C ANISOU 2834 CG LEU B 407 1913 1190 1620 -300 253 -47 C ATOM 2835 CD1 LEU B 407 -5.419 -64.062 21.664 1.00 16.25 C ANISOU 2835 CD1 LEU B 407 2205 1485 2483 -567 91 -388 C ATOM 2836 CD2 LEU B 407 -4.519 -63.380 23.927 1.00 16.08 C ANISOU 2836 CD2 LEU B 407 2630 1436 2043 -288 843 -112 C ATOM 2837 H LEU B 407 -3.430 -67.974 23.197 1.00 11.79 H ATOM 2838 HA LEU B 407 -4.220 -66.535 21.221 1.00 11.48 H ATOM 2839 HB2 LEU B 407 -4.793 -65.998 23.389 1.00 12.82 H ATOM 2840 HB3 LEU B 407 -3.292 -65.611 23.711 1.00 12.82 H ATOM 2841 HG LEU B 407 -3.491 -63.771 22.225 1.00 14.93 H ATOM 2842 HD11 LEU B 407 -5.579 -63.140 21.452 1.00 19.51 H ATOM 2843 HD12 LEU B 407 -5.181 -64.544 20.868 1.00 19.51 H ATOM 2844 HD13 LEU B 407 -6.203 -64.450 22.059 1.00 19.51 H ATOM 2845 HD21 LEU B 407 -4.706 -62.464 23.709 1.00 19.31 H ATOM 2846 HD22 LEU B 407 -5.268 -63.767 24.386 1.00 19.31 H ATOM 2847 HD23 LEU B 407 -3.734 -63.433 24.476 1.00 19.31 H ATOM 2848 N LEU B 408 -1.143 -66.124 21.858 1.00 10.02 N ANISOU 2848 N LEU B 408 1285 1062 1459 -45 -302 23 N ATOM 2849 CA LEU B 408 0.078 -65.590 21.338 1.00 10.40 C ANISOU 2849 CA LEU B 408 1339 1264 1348 -159 -393 -95 C ATOM 2850 C LEU B 408 0.442 -66.294 20.000 1.00 10.93 C ANISOU 2850 C LEU B 408 1042 1478 1631 -66 -335 -313 C ATOM 2851 O LEU B 408 0.810 -65.626 19.013 1.00 11.41 O ANISOU 2851 O LEU B 408 1090 1541 1703 -40 -142 -121 O ATOM 2852 CB LEU B 408 1.175 -65.703 22.392 1.00 11.35 C ANISOU 2852 CB LEU B 408 1312 1265 1737 -87 -178 -101 C ATOM 2853 CG LEU B 408 2.521 -65.055 22.071 1.00 12.65 C ANISOU 2853 CG LEU B 408 1480 1474 1851 9 93 -302 C ATOM 2854 CD1 LEU B 408 2.416 -63.600 21.737 1.00 13.31 C ANISOU 2854 CD1 LEU B 408 1619 1675 1765 285 -133 24 C ATOM 2855 CD2 LEU B 408 3.442 -65.230 23.277 1.00 12.03 C ANISOU 2855 CD2 LEU B 408 1284 1810 1478 76 -176 -70 C ATOM 2856 H LEU B 408 -1.059 -66.552 22.599 1.00 12.03 H ATOM 2857 HA LEU B 408 -0.052 -64.638 21.146 1.00 12.49 H ATOM 2858 HB2 LEU B 408 0.850 -65.294 23.210 1.00 13.64 H ATOM 2859 HB3 LEU B 408 1.343 -66.644 22.551 1.00 13.64 H ATOM 2860 HG LEU B 408 2.923 -65.510 21.315 1.00 15.19 H ATOM 2861 HD11 LEU B 408 3.293 -63.261 21.547 1.00 15.99 H ATOM 2862 HD12 LEU B 408 1.851 -63.497 20.967 1.00 15.99 H ATOM 2863 HD13 LEU B 408 2.038 -63.135 22.486 1.00 15.99 H ATOM 2864 HD21 LEU B 408 4.291 -64.825 23.083 1.00 14.45 H ATOM 2865 HD22 LEU B 408 3.043 -64.804 24.039 1.00 14.45 H ATOM 2866 HD23 LEU B 408 3.558 -66.168 23.447 1.00 14.45 H ATOM 2867 N ARG B 409 0.332 -67.636 19.952 1.00 11.70 N ANISOU 2867 N ARG B 409 1308 1399 1740 -285 -314 -18 N ATOM 2868 CA ARG B 409 0.538 -68.365 18.674 1.00 12.69 C ANISOU 2868 CA ARG B 409 1511 1614 1697 -346 -114 -45 C ATOM 2869 C ARG B 409 -0.369 -67.858 17.581 1.00 12.35 C ANISOU 2869 C ARG B 409 1541 1499 1653 -319 -98 285 C ATOM 2870 O ARG B 409 0.060 -67.647 16.448 1.00 13.91 O ANISOU 2870 O ARG B 409 1816 1833 1636 -504 155 165 O ATOM 2871 CB ARG B 409 0.276 -69.876 18.870 1.00 15.17 C ANISOU 2871 CB ARG B 409 1870 1603 2293 -558 -105 86 C ATOM 2872 CG ARG B 409 1.232 -70.618 19.784 1.00 16.40 C ANISOU 2872 CG ARG B 409 2355 1726 2151 -246 -212 -3 C ATOM 2873 CD ARG B 409 1.009 -72.178 19.673 1.00 21.95 C ANISOU 2873 CD ARG B 409 2852 2319 3169 -34 -757 -608 C ATOM 2874 NE ARG B 409 1.678 -72.834 20.852 1.00 23.32 N ANISOU 2874 NE ARG B 409 3850 2386 2623 342 -22 455 N ATOM 2875 CZ ARG B 409 1.092 -73.046 22.021 1.00 20.29 C ANISOU 2875 CZ ARG B 409 3039 1808 2863 -383 -84 182 C ATOM 2876 NH1 ARG B 409 -0.173 -72.822 22.156 1.00 20.77 N ANISOU 2876 NH1 ARG B 409 2609 2404 2880 -818 -450 458 N ATOM 2877 NH2 ARG B 409 1.759 -73.532 23.077 1.00 21.81 N ANISOU 2877 NH2 ARG B 409 3141 2104 3042 -343 -375 214 N ATOM 2878 H ARG B 409 0.143 -68.139 20.624 1.00 14.06 H ATOM 2879 HA ARG B 409 1.467 -68.248 18.382 1.00 15.24 H ATOM 2880 HB2 ARG B 409 -0.615 -69.984 19.238 1.00 18.22 H ATOM 2881 HB3 ARG B 409 0.318 -70.305 18.001 1.00 18.22 H ATOM 2882 HG2 ARG B 409 2.145 -70.418 19.526 1.00 19.70 H ATOM 2883 HG3 ARG B 409 1.073 -70.349 20.703 1.00 19.70 H ATOM 2884 HD2 ARG B 409 0.061 -72.380 19.698 1.00 26.35 H ATOM 2885 HD3 ARG B 409 1.413 -72.513 18.857 1.00 26.35 H ATOM 2886 HE ARG B 409 2.599 -73.120 20.749 1.00 27.99 H ATOM 2887 HH11 ARG B 409 -0.621 -72.483 21.505 1.00 24.94 H ATOM 2888 HH12 ARG B 409 -0.560 -72.980 22.908 1.00 24.94 H ATOM 2889 HH21 ARG B 409 2.594 -73.724 23.004 1.00 26.19 H ATOM 2890 HH22 ARG B 409 1.338 -73.716 23.803 1.00 26.19 H ATOM 2891 N AASP B 410 -1.644 -67.657 17.873 0.54 10.91 N ANISOU 2891 N AASP B 410 1467 1277 1401 -334 -54 90 N ATOM 2892 N BASP B 410 -1.660 -67.713 17.926 0.46 10.96 N ANISOU 2892 N BASP B 410 1370 1278 1518 -56 -50 167 N ATOM 2893 CA AASP B 410 -2.593 -67.255 16.850 0.54 12.49 C ANISOU 2893 CA AASP B 410 1663 1437 1646 -169 -518 115 C ATOM 2894 CA BASP B 410 -2.722 -67.231 17.037 0.46 10.48 C ANISOU 2894 CA BASP B 410 1408 1356 1217 -54 -453 48 C ATOM 2895 C AASP B 410 -2.410 -65.819 16.415 0.54 9.78 C ANISOU 2895 C AASP B 410 1082 1342 1291 -258 -225 361 C ATOM 2896 C BASP B 410 -2.327 -65.906 16.440 0.46 9.58 C ANISOU 2896 C BASP B 410 1032 1482 1127 -27 -228 128 C ATOM 2897 O AASP B 410 -2.716 -65.429 15.283 0.54 9.87 O ANISOU 2897 O AASP B 410 1124 1334 1292 -382 -213 -81 O ATOM 2898 O BASP B 410 -2.491 -65.660 15.249 0.46 10.26 O ANISOU 2898 O BASP B 410 1012 1818 1071 -137 -76 271 O ATOM 2899 CB AASP B 410 -3.987 -67.552 17.338 0.54 11.73 C ANISOU 2899 CB AASP B 410 1279 1566 1611 354 -354 195 C ATOM 2900 CB BASP B 410 -4.045 -67.001 17.772 0.46 11.60 C ANISOU 2900 CB BASP B 410 1637 1619 1153 362 -347 -67 C ATOM 2901 CG AASP B 410 -4.190 -69.034 17.524 0.54 15.89 C ANISOU 2901 CG AASP B 410 1755 1777 2507 -266 -317 437 C ATOM 2902 CG BASP B 410 -4.634 -68.234 18.345 0.46 11.61 C ANISOU 2902 CG BASP B 410 1441 1715 1255 -220 14 239 C ATOM 2903 OD1AASP B 410 -3.536 -69.796 16.783 0.54 22.19 O ANISOU 2903 OD1AASP B 410 2792 2365 3275 -336 474 726 O ATOM 2904 OD1BASP B 410 -4.363 -69.376 17.941 0.46 13.57 O ANISOU 2904 OD1BASP B 410 1713 1852 1591 -190 141 298 O ATOM 2905 OD2AASP B 410 -4.935 -69.439 18.426 0.54 11.59 O ANISOU 2905 OD2AASP B 410 1372 1438 1594 110 -68 223 O ATOM 2906 OD2BASP B 410 -5.430 -67.921 19.258 0.46 14.36 O ANISOU 2906 OD2BASP B 410 1557 1461 2437 174 -542 -582 O ATOM 2907 H AASP B 410 -1.985 -67.747 18.657 0.54 13.11 H ATOM 2908 H BASP B 410 -1.952 -67.897 18.714 0.46 13.17 H ATOM 2909 HA AASP B 410 -2.441 -67.815 16.060 0.54 15.00 H ATOM 2910 HA BASP B 410 -2.869 -67.876 16.313 0.46 12.59 H ATOM 2911 HB2AASP B 410 -4.129 -67.114 18.192 0.54 14.09 H ATOM 2912 HB2BASP B 410 -3.893 -66.380 18.501 0.46 13.94 H ATOM 2913 HB3AASP B 410 -4.631 -67.235 16.685 0.54 14.09 H ATOM 2914 HB3BASP B 410 -4.688 -66.627 17.150 0.46 13.94 H ATOM 2915 N SER B 411 -1.842 -65.017 17.293 1.00 9.83 N ANISOU 2915 N SER B 411 1243 1228 1263 -160 -121 -57 N ATOM 2916 CA SER B 411 -1.471 -63.643 16.934 1.00 10.12 C ANISOU 2916 CA SER B 411 1385 1426 1036 -13 -70 115 C ATOM 2917 C SER B 411 -0.348 -63.620 15.955 1.00 11.02 C ANISOU 2917 C SER B 411 1372 1699 1117 -126 -4 29 C ATOM 2918 O SER B 411 -0.388 -62.879 14.976 1.00 12.14 O ANISOU 2918 O SER B 411 1418 1861 1332 -151 -11 -122 O ATOM 2919 CB SER B 411 -1.113 -62.916 18.200 1.00 11.19 C ANISOU 2919 CB SER B 411 1494 1322 1437 -88 123 -154 C ATOM 2920 OG SER B 411 -2.212 -62.733 19.072 1.00 12.68 O ANISOU 2920 OG SER B 411 2012 1255 1549 -25 304 72 O ATOM 2921 H ASER B 411 -1.657 -65.234 18.104 0.54 11.81 H ATOM 2922 H BSER B 411 -1.712 -65.189 18.125 0.46 11.81 H ATOM 2923 HA SER B 411 -2.242 -63.194 16.528 1.00 12.16 H ATOM 2924 HB2 SER B 411 -0.432 -63.425 18.666 1.00 13.45 H ATOM 2925 HB3 SER B 411 -0.760 -62.043 17.965 1.00 13.45 H ATOM 2926 HG SER B 411 -2.888 -63.062 18.743 1.00 15.23 H ATOM 2927 N PHE B 412 0.701 -64.412 16.203 1.00 11.35 N ANISOU 2927 N PHE B 412 1136 1762 1416 -116 -224 -4 N ATOM 2928 CA PHE B 412 1.780 -64.529 15.269 1.00 13.43 C ANISOU 2928 CA PHE B 412 1297 2154 1653 -261 114 133 C ATOM 2929 C PHE B 412 1.289 -65.061 13.917 1.00 13.75 C ANISOU 2929 C PHE B 412 1226 2168 1832 -392 295 158 C ATOM 2930 O PHE B 412 1.786 -64.650 12.887 1.00 16.14 O ANISOU 2930 O PHE B 412 1445 2860 1829 -181 439 154 O ATOM 2931 CB PHE B 412 2.941 -65.374 15.876 1.00 15.61 C ANISOU 2931 CB PHE B 412 1548 2587 1796 -307 -51 -168 C ATOM 2932 CG PHE B 412 3.923 -64.534 16.651 1.00 15.67 C ANISOU 2932 CG PHE B 412 1443 2716 1796 -98 197 -623 C ATOM 2933 CD1 PHE B 412 3.628 -64.136 17.921 1.00 19.76 C ANISOU 2933 CD1 PHE B 412 1767 3072 2669 706 -186 -826 C ATOM 2934 CD2 PHE B 412 5.145 -64.304 16.165 1.00 19.59 C ANISOU 2934 CD2 PHE B 412 1625 2239 3578 -241 193 -727 C ATOM 2935 CE1 PHE B 412 4.512 -63.280 18.605 1.00 20.94 C ANISOU 2935 CE1 PHE B 412 2352 3302 2301 1088 -623 -581 C ATOM 2936 CE2 PHE B 412 6.045 -63.438 16.827 1.00 20.56 C ANISOU 2936 CE2 PHE B 412 2042 2660 3110 570 -287 -911 C ATOM 2937 CZ PHE B 412 5.707 -62.871 18.051 1.00 19.68 C ANISOU 2937 CZ PHE B 412 1842 3168 2468 1070 -515 -1397 C ATOM 2938 H PHE B 412 0.795 -64.888 16.913 1.00 13.64 H ATOM 2939 HA PHE B 412 2.137 -63.632 15.107 1.00 16.13 H ATOM 2940 HB2 PHE B 412 2.569 -66.035 16.480 1.00 18.75 H ATOM 2941 HB3 PHE B 412 3.422 -65.813 15.158 1.00 18.75 H ATOM 2942 HD1 PHE B 412 2.779 -64.291 18.267 1.00 23.73 H ATOM 2943 HD2 PHE B 412 5.337 -64.570 15.294 1.00 23.52 H ATOM 2944 HE1 PHE B 412 4.268 -62.955 19.442 1.00 25.14 H ATOM 2945 HE2 PHE B 412 6.862 -63.235 16.433 1.00 24.69 H ATOM 2946 HZ PHE B 412 6.333 -62.401 18.553 1.00 23.63 H ATOM 2947 N GLN B 413 0.350 -65.999 13.957 1.00 13.69 N ANISOU 2947 N GLN B 413 1622 2137 1440 -599 -10 231 N ATOM 2948 CA GLN B 413 -0.152 -66.562 12.704 1.00 15.12 C ANISOU 2948 CA GLN B 413 1962 2123 1658 -576 293 220 C ATOM 2949 C GLN B 413 -0.880 -65.498 11.939 1.00 13.70 C ANISOU 2949 C GLN B 413 1754 2223 1230 -361 142 293 C ATOM 2950 O GLN B 413 -0.836 -65.487 10.712 1.00 17.14 O ANISOU 2950 O GLN B 413 2057 3079 1378 -659 183 580 O ATOM 2951 CB GLN B 413 -1.067 -67.737 12.995 1.00 16.57 C ANISOU 2951 CB GLN B 413 2399 2032 1864 -247 -345 285 C ATOM 2952 CG GLN B 413 -0.492 -69.046 13.455 1.00 24.42 C ANISOU 2952 CG GLN B 413 3358 2962 2957 -125 -284 570 C ATOM 2953 CD GLN B 413 -1.687 -69.944 14.022 1.00 31.93 C ANISOU 2953 CD GLN B 413 4059 3715 4356 282 -521 -315 C ATOM 2954 OE1 GLN B 413 -2.922 -69.770 13.644 1.00 32.85 O ANISOU 2954 OE1 GLN B 413 4350 3281 4851 698 -491 482 O ATOM 2955 NE2 GLN B 413 -1.340 -70.850 14.934 1.00 38.36 N ANISOU 2955 NE2 GLN B 413 4855 4593 5128 94 -269 26 N ATOM 2956 H GLN B 413 -0.005 -66.319 14.671 1.00 16.44 H ATOM 2957 HA GLN B 413 0.600 -66.878 12.161 1.00 18.16 H ATOM 2958 HB2 GLN B 413 -1.692 -67.457 13.681 1.00 19.89 H ATOM 2959 HB3 GLN B 413 -1.563 -67.927 12.183 1.00 19.89 H ATOM 2960 HG2 GLN B 413 -0.079 -69.506 12.707 1.00 29.31 H ATOM 2961 HG3 GLN B 413 0.151 -68.892 14.165 1.00 29.31 H ATOM 2962 HE21 GLN B 413 -1.937 -71.365 15.278 1.00 46.05 H ATOM 2963 HE22 GLN B 413 -0.519 -70.919 15.180 1.00 46.05 H ATOM 2964 N GLN B 414 -1.664 -64.644 12.606 1.00 11.28 N ANISOU 2964 N GLN B 414 1252 1894 1139 -304 -61 181 N ATOM 2965 CA GLN B 414 -2.481 -63.679 11.858 1.00 11.32 C ANISOU 2965 CA GLN B 414 1168 2028 1106 -40 262 -15 C ATOM 2966 C GLN B 414 -1.705 -62.470 11.405 1.00 11.34 C ANISOU 2966 C GLN B 414 961 2023 1324 -154 -150 -180 C ATOM 2967 O GLN B 414 -2.071 -61.843 10.418 1.00 12.33 O ANISOU 2967 O GLN B 414 1047 2289 1349 -229 177 -298 O ATOM 2968 CB GLN B 414 -3.681 -63.241 12.685 1.00 11.10 C ANISOU 2968 CB GLN B 414 1267 1597 1354 13 -1 -82 C ATOM 2969 CG GLN B 414 -4.736 -62.648 11.746 1.00 12.05 C ANISOU 2969 CG GLN B 414 1640 1617 1321 -2 133 116 C ATOM 2970 CD GLN B 414 -5.861 -62.018 12.478 1.00 11.70 C ANISOU 2970 CD GLN B 414 1759 1582 1107 122 118 189 C ATOM 2971 OE1 GLN B 414 -5.627 -61.114 13.300 1.00 13.22 O ANISOU 2971 OE1 GLN B 414 1805 1573 1646 77 469 79 O ATOM 2972 NE2 GLN B 414 -7.112 -62.450 12.185 1.00 12.09 N ANISOU 2972 NE2 GLN B 414 1390 1655 1547 -161 128 148 N ATOM 2973 H GLN B 414 -1.741 -64.601 13.461 1.00 13.55 H ATOM 2974 HA GLN B 414 -2.825 -64.123 11.055 1.00 13.60 H ATOM 2975 HB2 GLN B 414 -4.064 -64.007 13.141 1.00 13.34 H ATOM 2976 HB3 GLN B 414 -3.411 -62.559 13.321 1.00 13.34 H ATOM 2977 HG2 GLN B 414 -4.321 -61.967 11.193 1.00 14.48 H ATOM 2978 HG3 GLN B 414 -5.098 -63.355 11.190 1.00 14.48 H ATOM 2979 HE21 GLN B 414 -7.791 -62.109 12.589 1.00 14.52 H ATOM 2980 HE22 GLN B 414 -7.228 -63.066 11.595 1.00 14.52 H ATOM 2981 N VAL B 415 -0.671 -62.054 12.131 1.00 11.64 N ANISOU 2981 N VAL B 415 1077 2070 1276 -5 138 -411 N ATOM 2982 CA VAL B 415 -0.075 -60.761 11.825 1.00 11.84 C ANISOU 2982 CA VAL B 415 1394 2025 1078 -162 -15 61 C ATOM 2983 C VAL B 415 0.509 -60.746 10.404 1.00 11.24 C ANISOU 2983 C VAL B 415 1224 1688 1359 -7 17 -224 C ATOM 2984 O VAL B 415 0.472 -59.681 9.777 1.00 12.96 O ANISOU 2984 O VAL B 415 1637 1840 1446 -118 54 -189 O ATOM 2985 CB VAL B 415 1.022 -60.355 12.829 1.00 14.43 C ANISOU 2985 CB VAL B 415 1685 2524 1275 341 212 -436 C ATOM 2986 CG1 VAL B 415 2.272 -61.290 12.808 1.00 15.56 C ANISOU 2986 CG1 VAL B 415 1516 2532 1863 372 -217 -645 C ATOM 2987 CG2 VAL B 415 1.404 -58.934 12.717 1.00 15.56 C ANISOU 2987 CG2 VAL B 415 2064 2499 1349 381 50 -28 C ATOM 2988 H VAL B 415 -0.308 -62.486 12.781 1.00 13.98 H ATOM 2989 HA VAL B 415 -0.777 -60.078 11.863 1.00 14.22 H ATOM 2990 HB VAL B 415 0.634 -60.455 13.723 1.00 17.34 H ATOM 2991 HG11 VAL B 415 2.907 -60.976 13.455 1.00 18.68 H ATOM 2992 HG12 VAL B 415 1.997 -62.183 13.025 1.00 18.68 H ATOM 2993 HG13 VAL B 415 2.661 -61.271 11.931 1.00 18.68 H ATOM 2994 HG21 VAL B 415 2.087 -58.742 13.364 1.00 18.69 H ATOM 2995 HG22 VAL B 415 1.736 -58.769 11.831 1.00 18.69 H ATOM 2996 HG23 VAL B 415 0.632 -58.389 12.885 1.00 18.69 H ATOM 2997 N VAL B 416 0.903 -61.884 9.876 1.00 12.43 N ANISOU 2997 N VAL B 416 1350 1910 1463 -187 401 -124 N ATOM 2998 CA VAL B 416 1.357 -61.977 8.499 1.00 13.63 C ANISOU 2998 CA VAL B 416 1283 2272 1625 -219 181 -119 C ATOM 2999 C VAL B 416 0.280 -61.797 7.440 1.00 14.56 C ANISOU 2999 C VAL B 416 1464 2281 1787 -215 306 142 C ATOM 3000 O VAL B 416 0.602 -61.557 6.266 1.00 18.72 O ANISOU 3000 O VAL B 416 2450 3169 1492 -655 489 -221 O ATOM 3001 CB VAL B 416 2.139 -63.291 8.270 1.00 17.62 C ANISOU 3001 CB VAL B 416 2299 2437 1957 -759 621 -294 C ATOM 3002 CG1 VAL B 416 3.295 -63.383 9.225 1.00 20.95 C ANISOU 3002 CG1 VAL B 416 2322 2823 2814 -947 411 -273 C ATOM 3003 CG2 VAL B 416 1.250 -64.490 8.258 1.00 22.12 C ANISOU 3003 CG2 VAL B 416 2886 2825 2694 -477 1057 -313 C ATOM 3004 H VAL B 416 0.919 -62.633 10.299 1.00 14.93 H ATOM 3005 HA VAL B 416 1.998 -61.249 8.358 1.00 16.37 H ATOM 3006 HB VAL B 416 2.533 -63.239 7.374 1.00 21.15 H ATOM 3007 HG11 VAL B 416 3.766 -64.204 9.067 1.00 25.15 H ATOM 3008 HG12 VAL B 416 3.880 -62.636 9.080 1.00 25.15 H ATOM 3009 HG13 VAL B 416 2.958 -63.366 10.124 1.00 25.15 H ATOM 3010 HG21 VAL B 416 1.785 -65.274 8.113 1.00 26.56 H ATOM 3011 HG22 VAL B 416 0.798 -64.553 9.103 1.00 26.56 H ATOM 3012 HG23 VAL B 416 0.608 -64.397 7.550 1.00 26.56 H ATOM 3013 N LYS B 417 -0.970 -61.853 7.874 1.00 13.26 N ANISOU 3013 N LYS B 417 1449 2168 1420 -309 30 59 N ATOM 3014 CA LYS B 417 -2.159 -61.729 6.983 1.00 13.57 C ANISOU 3014 CA LYS B 417 2009 1800 1347 -18 63 179 C ATOM 3015 C LYS B 417 -2.674 -60.303 6.914 1.00 13.45 C ANISOU 3015 C LYS B 417 2049 1840 1223 -78 -132 -42 C ATOM 3016 O LYS B 417 -3.519 -59.995 6.074 1.00 17.34 O ANISOU 3016 O LYS B 417 2675 2545 1367 -581 -605 64 O ATOM 3017 CB LYS B 417 -3.241 -62.662 7.440 1.00 14.21 C ANISOU 3017 CB LYS B 417 1940 1955 1503 39 -119 162 C ATOM 3018 CG LYS B 417 -2.758 -64.106 7.601 1.00 18.65 C ANISOU 3018 CG LYS B 417 2609 2236 2241 -69 154 408 C ATOM 3019 CD LYS B 417 -3.841 -65.064 8.039 1.00 18.73 C ANISOU 3019 CD LYS B 417 2507 2349 2261 219 138 333 C ATOM 3020 CE LYS B 417 -3.185 -66.413 8.352 1.00 21.98 C ANISOU 3020 CE LYS B 417 2763 2491 3097 -367 473 836 C ATOM 3021 NZ LYS B 417 -4.156 -67.300 8.907 1.00 22.45 N ANISOU 3021 NZ LYS B 417 2601 2862 3068 -525 183 617 N ATOM 3022 H LYS B 417 -1.179 -61.964 8.701 1.00 15.93 H ATOM 3023 HA LYS B 417 -1.900 -61.996 6.077 1.00 16.30 H ATOM 3024 HB2 LYS B 417 -3.575 -62.361 8.300 1.00 17.06 H ATOM 3025 HB3 LYS B 417 -3.958 -62.657 6.787 1.00 17.06 H ATOM 3026 HG2 LYS B 417 -2.413 -64.419 6.750 1.00 22.40 H ATOM 3027 HG3 LYS B 417 -2.055 -64.129 8.269 1.00 22.40 H ATOM 3028 HD2 LYS B 417 -4.273 -64.730 8.841 1.00 22.49 H ATOM 3029 HD3 LYS B 417 -4.484 -65.184 7.323 1.00 22.49 H ATOM 3030 HE2 LYS B 417 -2.838 -66.804 7.535 1.00 26.39 H ATOM 3031 HE3 LYS B 417 -2.473 -66.287 9.000 1.00 26.39 H ATOM 3032 HZ1 LYS B 417 -3.751 -68.147 9.105 1.00 26.96 H ATOM 3033 HZ2 LYS B 417 -4.514 -66.928 9.716 1.00 26.96 H ATOM 3034 HZ3 LYS B 417 -4.872 -67.436 8.282 1.00 26.96 H ATOM 3035 N LEU B 418 -2.198 -59.432 7.799 1.00 13.00 N ANISOU 3035 N LEU B 418 1499 1984 1454 -189 55 76 N ATOM 3036 CA LEU B 418 -2.772 -58.093 7.978 1.00 12.13 C ANISOU 3036 CA LEU B 418 1485 1881 1245 -82 -24 84 C ATOM 3037 C LEU B 418 -2.071 -56.978 7.226 1.00 15.51 C ANISOU 3037 C LEU B 418 1564 2343 1985 -42 239 380 C ATOM 3038 O LEU B 418 -2.156 -55.799 7.588 1.00 15.22 O ANISOU 3038 O LEU B 418 1842 2411 1530 43 14 -242 O ATOM 3039 CB LEU B 418 -2.899 -57.779 9.463 1.00 12.97 C ANISOU 3039 CB LEU B 418 1489 1745 1694 -37 -31 49 C ATOM 3040 CG LEU B 418 -3.748 -58.776 10.242 1.00 13.73 C ANISOU 3040 CG LEU B 418 1901 1830 1488 -21 215 -65 C ATOM 3041 CD1 LEU B 418 -3.743 -58.406 11.721 1.00 17.47 C ANISOU 3041 CD1 LEU B 418 2425 2268 1944 -50 669 -104 C ATOM 3042 CD2 LEU B 418 -5.151 -58.901 9.675 1.00 16.57 C ANISOU 3042 CD2 LEU B 418 1755 2279 2264 335 91 -251 C ATOM 3043 H LEU B 418 -1.532 -59.592 8.318 1.00 15.61 H ATOM 3044 HA LEU B 418 -3.686 -58.124 7.625 1.00 14.57 H ATOM 3045 HB2 LEU B 418 -2.013 -57.774 9.857 1.00 15.58 H ATOM 3046 HB3 LEU B 418 -3.306 -56.904 9.562 1.00 15.58 H ATOM 3047 HG LEU B 418 -3.332 -59.650 10.165 1.00 16.50 H ATOM 3048 HD11 LEU B 418 -4.280 -59.040 12.202 1.00 20.98 H ATOM 3049 HD12 LEU B 418 -2.840 -58.428 12.045 1.00 20.98 H ATOM 3050 HD13 LEU B 418 -4.107 -57.524 11.823 1.00 20.98 H ATOM 3051 HD21 LEU B 418 -5.644 -59.538 10.198 1.00 19.90 H ATOM 3052 HD22 LEU B 418 -5.580 -58.043 9.713 1.00 19.90 H ATOM 3053 HD23 LEU B 418 -5.095 -59.198 8.764 1.00 19.90 H ATOM 3054 N LYS B 419 -1.367 -57.328 6.149 1.00 18.59 N ANISOU 3054 N LYS B 419 2447 2505 2112 -234 501 -190 N ATOM 3055 CA LYS B 419 -0.902 -56.334 5.184 1.00 20.96 C ANISOU 3055 CA LYS B 419 2936 2872 2155 294 276 -892 C ATOM 3056 C LYS B 419 0.025 -55.352 5.858 1.00 17.46 C ANISOU 3056 C LYS B 419 2566 2210 1859 216 159 -593 C ATOM 3057 O LYS B 419 -0.014 -54.123 5.628 1.00 21.25 O ANISOU 3057 O LYS B 419 3107 2462 2505 -62 137 -408 O ATOM 3058 CB LYS B 419 -2.049 -55.581 4.479 1.00 22.18 C ANISOU 3058 CB LYS B 419 2744 3276 2409 364 -353 -1113 C ATOM 3059 CG LYS B 419 -3.088 -56.513 3.946 1.00 31.48 C ANISOU 3059 CG LYS B 419 4050 4081 3832 691 -526 -1049 C ATOM 3060 CD LYS B 419 -2.875 -56.880 2.537 1.00 40.04 C ANISOU 3060 CD LYS B 419 5039 5142 5031 320 418 293 C ATOM 3061 CE LYS B 419 -3.867 -57.918 2.042 1.00 47.03 C ANISOU 3061 CE LYS B 419 5952 6029 5888 136 176 -66 C ATOM 3062 NZ LYS B 419 -4.261 -57.688 0.603 1.00 54.31 N ANISOU 3062 NZ LYS B 419 6805 6837 6994 128 237 197 N ATOM 3063 H LYS B 419 -1.145 -58.136 5.955 1.00 22.32 H ATOM 3064 HA LYS B 419 -0.386 -56.794 4.490 1.00 25.16 H ATOM 3065 HB2 LYS B 419 -2.475 -54.984 5.113 1.00 26.64 H ATOM 3066 HB3 LYS B 419 -1.687 -55.075 3.735 1.00 26.64 H ATOM 3067 HG2 LYS B 419 -3.079 -57.328 4.472 1.00 37.80 H ATOM 3068 HG3 LYS B 419 -3.957 -56.085 4.014 1.00 37.80 H ATOM 3069 HD2 LYS B 419 -2.970 -56.088 1.986 1.00 48.06 H ATOM 3070 HD3 LYS B 419 -1.983 -57.248 2.438 1.00 48.06 H ATOM 3071 HE2 LYS B 419 -3.465 -58.800 2.107 1.00 56.45 H ATOM 3072 HE3 LYS B 419 -4.669 -57.877 2.585 1.00 56.45 H ATOM 3073 HZ1 LYS B 419 -4.887 -58.358 0.323 1.00 65.19 H ATOM 3074 HZ2 LYS B 419 -4.668 -56.823 0.509 1.00 65.19 H ATOM 3075 HZ3 LYS B 419 -3.485 -57.729 0.040 1.00 65.19 H ATOM 3076 N GLY B 420 0.815 -55.837 6.824 1.00 16.51 N ANISOU 3076 N GLY B 420 2146 2348 1778 249 146 -366 N ATOM 3077 CA GLY B 420 1.804 -54.974 7.476 1.00 17.03 C ANISOU 3077 CA GLY B 420 2527 2159 1786 495 317 -129 C ATOM 3078 C GLY B 420 1.312 -54.108 8.590 1.00 15.86 C ANISOU 3078 C GLY B 420 2316 1826 1884 285 -474 -256 C ATOM 3079 O GLY B 420 2.110 -53.377 9.169 1.00 18.08 O ANISOU 3079 O GLY B 420 2246 1901 2724 342 -352 -267 O ATOM 3080 H GLY B 420 0.799 -56.647 7.114 1.00 19.83 H ATOM 3081 HA2 GLY B 420 2.513 -55.533 7.832 1.00 20.45 H ATOM 3082 HA3 GLY B 420 2.195 -54.392 6.805 1.00 20.45 H ATOM 3083 N GLN B 421 -0.001 -54.178 8.898 1.00 16.74 N ANISOU 3083 N GLN B 421 2194 2230 1937 554 -237 -428 N ATOM 3084 CA GLN B 421 -0.568 -53.337 9.948 1.00 17.18 C ANISOU 3084 CA GLN B 421 1972 2173 2382 178 -883 38 C ATOM 3085 C GLN B 421 -0.180 -53.955 11.365 1.00 13.69 C ANISOU 3085 C GLN B 421 1495 1832 1874 262 -181 -507 C ATOM 3086 O GLN B 421 0.171 -55.111 11.458 1.00 12.88 O ANISOU 3086 O GLN B 421 1490 1838 1567 49 5 -290 O ATOM 3087 CB GLN B 421 -2.123 -53.401 9.959 1.00 21.66 C ANISOU 3087 CB GLN B 421 2737 2843 2651 -517 -1401 144 C ATOM 3088 CG GLN B 421 -2.951 -52.950 8.788 1.00 29.53 C ANISOU 3088 CG GLN B 421 3659 3490 4069 -868 -685 504 C ATOM 3089 CD GLN B 421 -4.450 -53.589 8.906 1.00 28.78 C ANISOU 3089 CD GLN B 421 3377 3879 3680 -565 557 464 C ATOM 3090 OE1 GLN B 421 -5.310 -53.091 9.692 1.00 32.77 O ANISOU 3090 OE1 GLN B 421 3509 4680 4262 -1082 104 69 O ATOM 3091 NE2 GLN B 421 -4.721 -54.727 8.155 1.00 21.46 N ANISOU 3091 NE2 GLN B 421 2452 2878 2822 -61 -66 26 N ATOM 3092 H GLN B 421 -0.567 -54.697 8.514 1.00 20.10 H ATOM 3093 HA GLN B 421 -0.260 -52.409 9.879 1.00 20.63 H ATOM 3094 HB2 GLN B 421 -2.366 -54.328 10.116 1.00 26.01 H ATOM 3095 HB3 GLN B 421 -2.422 -52.875 10.716 1.00 26.01 H ATOM 3096 HG2 GLN B 421 -3.025 -51.983 8.794 1.00 35.45 H ATOM 3097 HG3 GLN B 421 -2.547 -53.259 7.963 1.00 35.45 H ATOM 3098 HE21 GLN B 421 -5.500 -55.091 8.191 1.00 25.76 H ATOM 3099 HE22 GLN B 421 -4.111 -55.066 7.653 1.00 25.76 H ATOM 3100 N VAL B 422 -0.291 -53.133 12.410 1.00 14.60 N ANISOU 3100 N VAL B 422 1616 1731 2198 292 197 -701 N ATOM 3101 CA VAL B 422 0.011 -53.592 13.762 1.00 12.19 C ANISOU 3101 CA VAL B 422 1372 1443 1817 75 107 -550 C ATOM 3102 C VAL B 422 -1.067 -54.448 14.346 1.00 11.89 C ANISOU 3102 C VAL B 422 1360 1343 1815 40 400 -353 C ATOM 3103 O VAL B 422 -2.258 -54.141 14.273 1.00 14.67 O ANISOU 3103 O VAL B 422 1259 1687 2628 7 121 -554 O ATOM 3104 CB VAL B 422 0.222 -52.393 14.750 1.00 14.20 C ANISOU 3104 CB VAL B 422 1739 1475 2182 139 393 -282 C ATOM 3105 CG1 VAL B 422 0.414 -52.852 16.177 1.00 16.44 C ANISOU 3105 CG1 VAL B 422 2187 1831 2230 -8 264 32 C ATOM 3106 CG2 VAL B 422 1.404 -51.556 14.289 1.00 18.28 C ANISOU 3106 CG2 VAL B 422 2177 2018 2750 358 140 -247 C ATOM 3107 H VAL B 422 -0.538 -52.310 12.361 1.00 17.53 H ATOM 3108 HA VAL B 422 0.839 -54.117 13.742 1.00 14.64 H ATOM 3109 HB VAL B 422 -0.575 -51.822 14.726 1.00 17.05 H ATOM 3110 HG11 VAL B 422 0.537 -52.082 16.739 1.00 19.75 H ATOM 3111 HG12 VAL B 422 -0.365 -53.339 16.456 1.00 19.75 H ATOM 3112 HG13 VAL B 422 1.188 -53.417 16.222 1.00 19.75 H ATOM 3113 HG21 VAL B 422 1.525 -50.825 14.899 1.00 21.95 H ATOM 3114 HG22 VAL B 422 2.190 -52.106 14.277 1.00 21.95 H ATOM 3115 HG23 VAL B 422 1.224 -51.221 13.407 1.00 21.95 H ATOM 3116 N LEU B 423 -0.644 -55.551 14.929 1.00 10.47 N ANISOU 3116 N LEU B 423 1163 1441 1373 37 167 -371 N ATOM 3117 CA LEU B 423 -1.499 -56.405 15.753 1.00 10.73 C ANISOU 3117 CA LEU B 423 1317 1574 1184 145 -176 -299 C ATOM 3118 C LEU B 423 -0.935 -56.370 17.144 1.00 11.46 C ANISOU 3118 C LEU B 423 1101 1776 1475 323 177 -320 C ATOM 3119 O LEU B 423 0.264 -56.606 17.356 1.00 13.06 O ANISOU 3119 O LEU B 423 1211 2298 1452 296 -11 -207 O ATOM 3120 CB LEU B 423 -1.429 -57.868 15.215 1.00 12.06 C ANISOU 3120 CB LEU B 423 1404 1791 1387 -37 89 -199 C ATOM 3121 CG LEU B 423 -2.334 -58.872 15.928 1.00 14.72 C ANISOU 3121 CG LEU B 423 2315 1471 1807 -68 500 -311 C ATOM 3122 CD1 LEU B 423 -2.739 -60.040 15.065 1.00 17.53 C ANISOU 3122 CD1 LEU B 423 2723 1801 2139 357 415 13 C ATOM 3123 CD2 LEU B 423 -1.624 -59.498 17.104 1.00 20.32 C ANISOU 3123 CD2 LEU B 423 2853 2147 2722 482 148 -382 C ATOM 3124 H LEU B 423 0.163 -55.842 14.864 1.00 12.57 H ATOM 3125 HA LEU B 423 -2.426 -56.087 15.754 1.00 12.89 H ATOM 3126 HB2 LEU B 423 -1.682 -57.864 14.278 1.00 14.49 H ATOM 3127 HB3 LEU B 423 -0.517 -58.185 15.303 1.00 14.49 H ATOM 3128 HG LEU B 423 -3.134 -58.425 16.248 1.00 17.68 H ATOM 3129 HD11 LEU B 423 -3.303 -60.626 15.576 1.00 21.06 H ATOM 3130 HD12 LEU B 423 -3.216 -59.712 14.299 1.00 21.06 H ATOM 3131 HD13 LEU B 423 -1.949 -60.508 14.783 1.00 21.06 H ATOM 3132 HD21 LEU B 423 -2.216 -60.122 17.530 1.00 24.40 H ATOM 3133 HD22 LEU B 423 -0.840 -59.953 16.789 1.00 24.40 H ATOM 3134 HD23 LEU B 423 -1.375 -58.808 17.723 1.00 24.40 H ATOM 3135 N ASER B 424 -1.828 -56.148 18.106 0.54 12.21 N ANISOU 3135 N ASER B 424 1460 1597 1581 436 284 -317 N ATOM 3136 N BSER B 424 -1.746 -56.071 18.149 0.46 12.32 N ANISOU 3136 N BSER B 424 1391 1777 1514 75 21 -365 N ATOM 3137 CA ASER B 424 -1.473 -56.061 19.519 0.54 12.53 C ANISOU 3137 CA ASER B 424 1853 1517 1389 520 10 30 C ATOM 3138 CA BSER B 424 -1.235 -56.146 19.514 0.46 12.74 C ANISOU 3138 CA BSER B 424 2040 1665 1137 364 105 -203 C ATOM 3139 C ASER B 424 -1.864 -57.369 20.197 0.54 10.87 C ANISOU 3139 C ASER B 424 1649 1277 1203 277 206 260 C ATOM 3140 C BSER B 424 -1.925 -57.187 20.331 0.46 13.41 C ANISOU 3140 C BSER B 424 1744 2043 1308 606 360 -681 C ATOM 3141 O ASER B 424 -2.843 -58.002 19.832 0.54 11.95 O ANISOU 3141 O ASER B 424 1586 950 2006 133 246 204 O ATOM 3142 O BSER B 424 -3.075 -57.566 20.117 0.46 14.76 O ANISOU 3142 O BSER B 424 1630 2343 1634 766 4 -668 O ATOM 3143 CB ASER B 424 -2.226 -54.906 20.174 0.54 17.55 C ANISOU 3143 CB ASER B 424 2605 1842 2220 706 -296 -554 C ATOM 3144 CB BSER B 424 -1.391 -54.867 20.214 0.46 12.80 C ANISOU 3144 CB BSER B 424 1855 1648 1362 216 194 -66 C ATOM 3145 OG ASER B 424 -1.585 -54.532 21.384 0.54 22.94 O ANISOU 3145 OG ASER B 424 3148 2870 2698 256 89 -231 O ATOM 3146 OG BSER B 424 -0.922 -53.822 19.431 0.46 20.03 O ANISOU 3146 OG BSER B 424 3022 2057 2533 316 -153 -241 O ATOM 3147 H ASER B 424 -2.669 -56.042 17.960 0.55 14.66 H ATOM 3148 H BSER B 424 -2.568 -55.831 18.076 0.45 14.80 H ATOM 3149 HA ASER B 424 -0.508 -55.919 19.620 0.55 15.05 H ATOM 3150 HA BSER B 424 -0.280 -56.364 19.487 0.45 15.31 H ATOM 3151 HB2ASER B 424 -2.233 -54.147 19.570 0.55 21.07 H ATOM 3152 HB2BSER B 424 -2.331 -54.723 20.404 0.45 15.38 H ATOM 3153 HB3ASER B 424 -3.134 -55.188 20.368 0.55 21.07 H ATOM 3154 HB3BSER B 424 -0.885 -54.895 21.041 0.45 15.38 H ATOM 3155 HG ASER B 424 -1.990 -53.913 21.735 0.55 27.54 H ATOM 3156 HG BSER B 424 -1.013 -53.110 19.829 0.45 24.05 H ATOM 3157 N VAL B 425 -1.153 -57.692 21.248 1.00 10.22 N ANISOU 3157 N VAL B 425 1322 1346 1214 380 133 -145 N ATOM 3158 CA VAL B 425 -1.549 -58.763 22.133 1.00 11.18 C ANISOU 3158 CA VAL B 425 1454 1529 1266 325 46 -107 C ATOM 3159 C VAL B 425 -1.046 -58.483 23.548 1.00 9.79 C ANISOU 3159 C VAL B 425 1167 1285 1268 377 156 -180 C ATOM 3160 O VAL B 425 0.066 -58.012 23.722 1.00 12.32 O ANISOU 3160 O VAL B 425 1542 1921 1220 765 352 174 O ATOM 3161 CB VAL B 425 -1.023 -60.156 21.595 1.00 11.99 C ANISOU 3161 CB VAL B 425 1732 1510 1315 178 274 45 C ATOM 3162 CG1 VAL B 425 0.466 -60.226 21.567 1.00 14.31 C ANISOU 3162 CG1 VAL B 425 1984 1504 1948 173 377 -10 C ATOM 3163 CG2 VAL B 425 -1.595 -61.293 22.380 1.00 15.43 C ANISOU 3163 CG2 VAL B 425 2197 1754 1911 456 334 323 C ATOM 3164 H AVAL B 425 -0.422 -57.303 21.477 0.54 12.27 H ATOM 3165 H BVAL B 425 -0.349 -57.422 21.389 0.46 12.27 H ATOM 3166 HA VAL B 425 -2.528 -58.803 22.164 1.00 13.44 H ATOM 3167 HB VAL B 425 -1.333 -60.261 20.671 1.00 14.41 H ATOM 3168 HG11 VAL B 425 0.731 -61.088 21.235 1.00 17.18 H ATOM 3169 HG12 VAL B 425 0.800 -59.535 20.990 1.00 17.18 H ATOM 3170 HG13 VAL B 425 0.801 -60.101 22.457 1.00 17.18 H ATOM 3171 HG21 VAL B 425 -1.255 -62.117 22.027 1.00 18.53 H ATOM 3172 HG22 VAL B 425 -1.336 -61.197 23.300 1.00 18.53 H ATOM 3173 HG23 VAL B 425 -2.552 -61.273 22.305 1.00 18.53 H ATOM 3174 N AMET B 426 -1.861 -58.771 24.549 0.60 9.41 N ANISOU 3174 N AMET B 426 1126 1252 1198 321 -35 -248 N ATOM 3175 N BMET B 426 -1.906 -58.819 24.503 0.40 9.77 N ANISOU 3175 N BMET B 426 1352 1306 1055 -56 195 -181 N ATOM 3176 CA AMET B 426 -1.403 -58.721 25.934 0.60 8.82 C ANISOU 3176 CA AMET B 426 949 1165 1237 91 19 -304 C ATOM 3177 CA BMET B 426 -1.558 -58.843 25.910 0.40 11.82 C ANISOU 3177 CA BMET B 426 1467 1474 1548 -339 381 352 C ATOM 3178 C AMET B 426 -1.295 -60.141 26.436 0.60 9.34 C ANISOU 3178 C AMET B 426 1343 1158 1049 317 219 -183 C ATOM 3179 C BMET B 426 -1.225 -60.253 26.309 0.40 11.99 C ANISOU 3179 C BMET B 426 1544 1553 1458 21 -49 163 C ATOM 3180 O AMET B 426 -2.136 -60.992 26.181 0.60 10.46 O ANISOU 3180 O AMET B 426 1191 1147 1635 475 26 -356 O ATOM 3181 O BMET B 426 -1.878 -61.215 25.894 0.40 12.24 O ANISOU 3181 O BMET B 426 1403 1830 1418 -122 -103 342 O ATOM 3182 CB AMET B 426 -2.444 -58.019 26.780 0.60 14.33 C ANISOU 3182 CB AMET B 426 1839 1641 1966 105 -84 -464 C ATOM 3183 CB BMET B 426 -2.778 -58.433 26.723 0.40 12.99 C ANISOU 3183 CB BMET B 426 1854 1747 1332 -527 -317 667 C ATOM 3184 CG AMET B 426 -2.260 -56.564 26.964 0.60 16.54 C ANISOU 3184 CG AMET B 426 2461 1874 1951 -199 -166 -589 C ATOM 3185 CG BMET B 426 -3.080 -56.983 26.611 0.40 14.49 C ANISOU 3185 CG BMET B 426 1867 1865 1774 -14 -97 114 C ATOM 3186 SD AMET B 426 -3.512 -56.039 28.174 0.60 20.26 S ANISOU 3186 SD AMET B 426 2202 1935 3561 -465 803 555 S ATOM 3187 SD BMET B 426 -2.073 -55.983 27.768 0.40 20.34 S ANISOU 3187 SD BMET B 426 2194 2383 3153 342 605 873 S ATOM 3188 CE AMET B 426 -2.690 -56.404 29.821 0.60 16.46 C ANISOU 3188 CE AMET B 426 1791 1555 2909 -47 -1136 130 C ATOM 3189 CE BMET B 426 -3.087 -56.178 29.096 0.40 10.60 C ANISOU 3189 CE BMET B 426 1375 1846 805 -931 154 -586 C ATOM 3190 H AMET B 426 -2.685 -58.998 24.457 0.60 11.31 H ATOM 3191 H BMET B 426 -2.722 -59.044 24.351 0.40 11.74 H ATOM 3192 HA AMET B 426 -0.543 -58.257 26.005 0.60 10.60 H ATOM 3193 HA BMET B 426 -0.810 -58.237 26.099 0.40 14.19 H ATOM 3194 HB2AMET B 426 -3.311 -58.150 26.367 0.60 17.21 H ATOM 3195 HB2BMET B 426 -3.551 -58.926 26.405 0.40 15.60 H ATOM 3196 HB3AMET B 426 -2.443 -58.423 27.662 0.60 17.21 H ATOM 3197 HB3BMET B 426 -2.618 -58.635 27.658 0.40 15.60 H ATOM 3198 HG2AMET B 426 -1.376 -56.378 27.317 0.60 19.87 H ATOM 3199 HG2BMET B 426 -2.888 -56.686 25.708 0.40 17.41 H ATOM 3200 HG3AMET B 426 -2.410 -56.098 26.126 0.60 19.87 H ATOM 3201 HG3BMET B 426 -4.016 -56.836 26.820 0.40 17.41 H ATOM 3202 HE1AMET B 426 -3.288 -56.154 30.529 0.60 19.77 H ATOM 3203 HE1BMET B 426 -2.717 -55.706 29.844 0.40 12.73 H ATOM 3204 HE2AMET B 426 -2.495 -57.342 29.872 0.60 19.77 H ATOM 3205 HE2BMET B 426 -3.954 -55.826 28.881 0.40 12.73 H ATOM 3206 HE3AMET B 426 -1.878 -55.895 29.883 0.60 19.77 H ATOM 3207 HE3BMET B 426 -3.156 -57.114 29.300 0.40 12.73 H ATOM 3208 N PHE B 427 -0.211 -60.401 27.150 1.00 9.41 N ANISOU 3208 N PHE B 427 1197 1208 1170 330 -32 -108 N ATOM 3209 CA PHE B 427 0.073 -61.752 27.659 1.00 9.75 C ANISOU 3209 CA PHE B 427 1375 1069 1262 279 54 -228 C ATOM 3210 C PHE B 427 0.981 -61.628 28.871 1.00 8.58 C ANISOU 3210 C PHE B 427 1167 1024 1067 177 181 -90 C ATOM 3211 O PHE B 427 1.658 -60.620 29.077 1.00 10.11 O ANISOU 3211 O PHE B 427 1632 1033 1178 364 83 -160 O ATOM 3212 CB PHE B 427 0.654 -62.692 26.600 1.00 10.39 C ANISOU 3212 CB PHE B 427 1611 1294 1043 110 134 68 C ATOM 3213 CG PHE B 427 2.033 -62.392 26.181 1.00 10.67 C ANISOU 3213 CG PHE B 427 1480 1441 1134 382 119 95 C ATOM 3214 CD1 PHE B 427 3.096 -63.103 26.713 1.00 11.22 C ANISOU 3214 CD1 PHE B 427 1400 1478 1384 324 32 209 C ATOM 3215 CD2 PHE B 427 2.299 -61.389 25.255 1.00 12.20 C ANISOU 3215 CD2 PHE B 427 1786 1726 1123 440 99 -137 C ATOM 3216 CE1 PHE B 427 4.393 -62.880 26.329 1.00 12.30 C ANISOU 3216 CE1 PHE B 427 1927 1446 1302 229 62 136 C ATOM 3217 CE2 PHE B 427 3.618 -61.151 24.872 1.00 13.78 C ANISOU 3217 CE2 PHE B 427 1947 1976 1312 585 286 -187 C ATOM 3218 CZ PHE B 427 4.662 -61.894 25.424 1.00 14.76 C ANISOU 3218 CZ PHE B 427 1949 2042 1616 435 376 165 C ATOM 3219 H APHE B 427 0.383 -59.816 27.360 0.60 11.31 H ATOM 3220 H BPHE B 427 0.307 -59.776 27.434 0.40 11.31 H ATOM 3221 HA PHE B 427 -0.769 -62.148 27.966 1.00 11.72 H ATOM 3222 HB2 PHE B 427 0.647 -63.595 26.953 1.00 12.48 H ATOM 3223 HB3 PHE B 427 0.093 -62.649 25.810 1.00 12.48 H ATOM 3224 HD1 PHE B 427 2.920 -63.781 27.326 1.00 13.48 H ATOM 3225 HD2 PHE B 427 1.604 -60.896 24.883 1.00 14.65 H ATOM 3226 HE1 PHE B 427 5.086 -63.373 26.705 1.00 14.78 H ATOM 3227 HE2 PHE B 427 3.805 -60.482 24.254 1.00 16.55 H ATOM 3228 HZ PHE B 427 5.540 -61.724 25.168 1.00 17.72 H ATOM 3229 N ARG B 428 1.042 -62.715 29.622 1.00 8.43 N ANISOU 3229 N ARG B 428 1119 935 1150 192 13 -29 N ATOM 3230 CA ARG B 428 1.895 -62.797 30.774 1.00 8.21 C ANISOU 3230 CA ARG B 428 1030 1003 1086 36 41 -19 C ATOM 3231 C ARG B 428 3.221 -63.440 30.363 1.00 8.33 C ANISOU 3231 C ARG B 428 1117 983 1066 -12 64 24 C ATOM 3232 O ARG B 428 3.266 -64.553 29.853 1.00 9.01 O ANISOU 3232 O ARG B 428 1348 842 1234 82 166 94 O ATOM 3233 CB ARG B 428 1.172 -63.581 31.873 1.00 9.17 C ANISOU 3233 CB ARG B 428 1323 1170 991 86 94 30 C ATOM 3234 CG ARG B 428 0.019 -62.773 32.460 1.00 10.07 C ANISOU 3234 CG ARG B 428 1363 1255 1209 167 283 105 C ATOM 3235 CD ARG B 428 -0.979 -63.666 33.166 1.00 10.22 C ANISOU 3235 CD ARG B 428 1362 1371 1151 -34 182 20 C ATOM 3236 NE ARG B 428 -1.808 -64.334 32.175 1.00 10.58 N ANISOU 3236 NE ARG B 428 1286 1416 1316 212 203 19 N ATOM 3237 CZ ARG B 428 -2.896 -65.055 32.498 1.00 11.91 C ANISOU 3237 CZ ARG B 428 1478 1747 1299 322 175 46 C ATOM 3238 NH1 ARG B 428 -3.127 -65.302 33.791 1.00 14.29 N ANISOU 3238 NH1 ARG B 428 1833 1973 1623 674 174 -265 N ATOM 3239 NH2 ARG B 428 -3.653 -65.556 31.567 1.00 14.02 N ANISOU 3239 NH2 ARG B 428 1750 2100 1476 502 34 56 N ATOM 3240 H ARG B 428 0.585 -63.428 29.476 1.00 10.13 H ATOM 3241 HA ARG B 428 2.080 -61.894 31.108 1.00 9.86 H ATOM 3242 HB2 ARG B 428 0.811 -64.400 31.498 1.00 11.02 H ATOM 3243 HB3 ARG B 428 1.796 -63.784 32.587 1.00 11.02 H ATOM 3244 HG2 ARG B 428 0.368 -62.139 33.104 1.00 12.10 H ATOM 3245 HG3 ARG B 428 -0.443 -62.309 31.745 1.00 12.10 H ATOM 3246 HD2 ARG B 428 -0.509 -64.338 33.684 1.00 12.28 H ATOM 3247 HD3 ARG B 428 -1.551 -63.130 33.738 1.00 12.28 H ATOM 3248 HE ARG B 428 -1.681 -64.097 31.243 1.00 12.71 H ATOM 3249 HH11 ARG B 428 -2.627 -64.944 34.393 1.00 17.16 H ATOM 3250 HH12 ARG B 428 -3.803 -65.779 34.023 1.00 17.16 H ATOM 3251 HH21 ARG B 428 -3.466 -65.417 30.740 1.00 16.84 H ATOM 3252 HH22 ARG B 428 -4.313 -66.066 31.779 1.00 16.84 H ATOM 3253 N PHE B 429 4.326 -62.737 30.649 1.00 8.43 N ANISOU 3253 N PHE B 429 1087 991 1125 35 138 151 N ATOM 3254 CA PHE B 429 5.666 -63.105 30.282 1.00 7.98 C ANISOU 3254 CA PHE B 429 1115 977 939 67 192 77 C ATOM 3255 C PHE B 429 6.439 -63.446 31.556 1.00 8.24 C ANISOU 3255 C PHE B 429 1174 903 1052 85 184 211 C ATOM 3256 O PHE B 429 6.394 -62.695 32.534 1.00 9.03 O ANISOU 3256 O PHE B 429 1353 1018 1059 15 64 203 O ATOM 3257 CB PHE B 429 6.339 -61.882 29.595 1.00 9.80 C ANISOU 3257 CB PHE B 429 1325 1044 1354 80 188 93 C ATOM 3258 CG PHE B 429 7.646 -62.133 28.925 1.00 9.86 C ANISOU 3258 CG PHE B 429 1254 1100 1392 145 74 34 C ATOM 3259 CD1 PHE B 429 7.747 -62.022 27.569 1.00 12.29 C ANISOU 3259 CD1 PHE B 429 1403 1851 1414 132 58 98 C ATOM 3260 CD2 PHE B 429 8.793 -62.496 29.569 1.00 11.14 C ANISOU 3260 CD2 PHE B 429 1417 1215 1600 101 59 -105 C ATOM 3261 CE1 PHE B 429 8.950 -62.227 26.898 1.00 15.12 C ANISOU 3261 CE1 PHE B 429 1555 2099 2090 407 618 517 C ATOM 3262 CE2 PHE B 429 10.020 -62.724 28.881 1.00 13.06 C ANISOU 3262 CE2 PHE B 429 1335 1315 2312 132 242 -180 C ATOM 3263 CZ PHE B 429 10.076 -62.582 27.577 1.00 13.62 C ANISOU 3263 CZ PHE B 429 1325 1458 2392 302 421 323 C ATOM 3264 H PHE B 429 4.302 -61.998 31.086 1.00 10.13 H ATOM 3265 HA PHE B 429 5.665 -63.875 29.674 1.00 9.59 H ATOM 3266 HB2 PHE B 429 5.731 -61.540 28.921 1.00 11.77 H ATOM 3267 HB3 PHE B 429 6.487 -61.200 30.268 1.00 11.77 H ATOM 3268 HD1 PHE B 429 6.996 -61.769 27.081 1.00 14.76 H ATOM 3269 HD2 PHE B 429 8.775 -62.591 30.494 1.00 13.38 H ATOM 3270 HE1 PHE B 429 8.980 -62.136 25.973 1.00 18.16 H ATOM 3271 HE2 PHE B 429 10.782 -62.962 29.356 1.00 15.69 H ATOM 3272 HZ PHE B 429 10.872 -62.735 27.120 1.00 16.36 H ATOM 3273 N ARG B 430 7.092 -64.614 31.576 1.00 7.76 N ANISOU 3273 N ARG B 430 1035 1023 890 -55 48 160 N ATOM 3274 CA ARG B 430 7.814 -65.059 32.746 1.00 8.05 C ANISOU 3274 CA ARG B 430 1057 999 1002 16 140 192 C ATOM 3275 C ARG B 430 9.158 -64.356 32.860 1.00 8.53 C ANISOU 3275 C ARG B 430 1203 1104 935 -51 59 91 C ATOM 3276 O ARG B 430 10.032 -64.559 32.009 1.00 9.40 O ANISOU 3276 O ARG B 430 1134 1316 1121 -35 17 140 O ATOM 3277 CB ARG B 430 8.047 -66.564 32.650 1.00 8.61 C ANISOU 3277 CB ARG B 430 1234 1122 918 33 -82 -2 C ATOM 3278 CG ARG B 430 8.607 -67.129 33.894 1.00 10.43 C ANISOU 3278 CG ARG B 430 1542 1214 1207 -7 65 130 C ATOM 3279 CD ARG B 430 9.092 -68.627 33.745 1.00 10.79 C ANISOU 3279 CD ARG B 430 1868 1233 1001 79 39 -36 C ATOM 3280 NE ARG B 430 10.208 -68.677 32.842 1.00 10.78 N ANISOU 3280 NE ARG B 430 1804 1253 1039 -166 -120 -100 N ATOM 3281 CZ ARG B 430 10.170 -69.040 31.572 1.00 10.31 C ANISOU 3281 CZ ARG B 430 1632 1030 1256 -120 -36 -66 C ATOM 3282 NH1 ARG B 430 9.128 -69.659 31.087 1.00 11.71 N ANISOU 3282 NH1 ARG B 430 1856 1427 1168 -37 92 70 N ATOM 3283 NH2 ARG B 430 11.262 -68.779 30.847 1.00 14.00 N ANISOU 3283 NH2 ARG B 430 1945 1612 1762 -16 454 -2 N ATOM 3284 H ARG B 430 7.125 -65.162 30.915 1.00 9.32 H ATOM 3285 HA ARG B 430 7.290 -64.870 33.553 1.00 9.67 H ATOM 3286 HB2 ARG B 430 7.201 -67.005 32.474 1.00 10.35 H ATOM 3287 HB3 ARG B 430 8.672 -66.743 31.930 1.00 10.35 H ATOM 3288 HG2 ARG B 430 9.370 -66.595 34.165 1.00 12.53 H ATOM 3289 HG3 ARG B 430 7.926 -67.103 34.585 1.00 12.53 H ATOM 3290 HD2 ARG B 430 9.375 -68.966 34.609 1.00 12.97 H ATOM 3291 HD3 ARG B 430 8.374 -69.169 33.383 1.00 12.97 H ATOM 3292 HE ARG B 430 11.072 -68.418 33.198 1.00 12.95 H ATOM 3293 HH11 ARG B 430 8.425 -69.761 31.571 1.00 14.07 H ATOM 3294 HH12 ARG B 430 9.132 -69.932 30.271 1.00 14.07 H ATOM 3295 HH21 ARG B 430 11.946 -68.416 31.221 1.00 16.82 H ATOM 3296 HH22 ARG B 430 11.329 -69.093 30.049 1.00 16.82 H ATOM 3297 N SER B 431 9.327 -63.531 33.904 1.00 8.75 N ANISOU 3297 N SER B 431 1263 1102 960 110 10 122 N ATOM 3298 CA SER B 431 10.566 -62.823 34.054 1.00 8.83 C ANISOU 3298 CA SER B 431 1191 1044 1120 111 -92 133 C ATOM 3299 C SER B 431 11.703 -63.752 34.467 1.00 9.16 C ANISOU 3299 C SER B 431 1213 1242 1025 222 -1 114 C ATOM 3300 O SER B 431 11.487 -64.933 34.804 1.00 10.18 O ANISOU 3300 O SER B 431 1389 1182 1298 187 -60 -27 O ATOM 3301 CB SER B 431 10.442 -61.748 35.107 1.00 9.99 C ANISOU 3301 CB SER B 431 1400 1255 1142 95 -86 114 C ATOM 3302 OG SER B 431 10.510 -62.348 36.386 1.00 11.33 O ANISOU 3302 OG SER B 431 1771 1379 1154 -49 -30 181 O ATOM 3303 H SER B 431 8.743 -63.379 34.517 1.00 10.51 H ATOM 3304 HA SER B 431 10.805 -62.400 33.203 1.00 10.61 H ATOM 3305 HB2 SER B 431 11.172 -61.115 35.009 1.00 12.00 H ATOM 3306 HB3 SER B 431 9.590 -61.297 35.008 1.00 12.00 H ATOM 3307 HG SER B 431 10.444 -61.775 36.969 1.00 13.61 H ATOM 3308 N LYS B 432 12.938 -63.232 34.459 1.00 10.34 N ANISOU 3308 N LYS B 432 1277 1414 1238 108 -83 28 N ATOM 3309 CA LYS B 432 14.089 -63.992 34.911 1.00 10.93 C ANISOU 3309 CA LYS B 432 1252 1749 1153 72 -120 12 C ATOM 3310 C LYS B 432 13.900 -64.468 36.345 1.00 11.74 C ANISOU 3310 C LYS B 432 1319 1680 1463 -22 -402 -2 C ATOM 3311 O LYS B 432 14.513 -65.463 36.761 1.00 14.15 O ANISOU 3311 O LYS B 432 1794 1936 1646 -235 -29 -257 O ATOM 3312 CB LYS B 432 15.323 -63.094 34.791 1.00 12.96 C ANISOU 3312 CB LYS B 432 1450 1959 1517 207 -195 -48 C ATOM 3313 CG LYS B 432 16.613 -63.712 35.226 1.00 15.02 C ANISOU 3313 CG LYS B 432 1438 2127 2141 201 -489 38 C ATOM 3314 CD LYS B 432 17.085 -64.915 34.381 1.00 16.57 C ANISOU 3314 CD LYS B 432 2117 2083 2096 -107 -451 200 C ATOM 3315 CE LYS B 432 18.430 -65.457 34.940 1.00 18.86 C ANISOU 3315 CE LYS B 432 2460 2317 2387 -281 -505 186 C ATOM 3316 NZ LYS B 432 18.859 -66.537 34.144 1.00 19.15 N ANISOU 3316 NZ LYS B 432 2579 2435 2261 114 -320 -236 N ATOM 3317 H LYS B 432 13.127 -62.437 34.193 1.00 12.42 H ATOM 3318 HA LYS B 432 14.214 -64.775 34.335 1.00 13.13 H ATOM 3319 HB2 LYS B 432 15.424 -62.836 33.861 1.00 15.57 H ATOM 3320 HB3 LYS B 432 15.181 -62.304 35.334 1.00 15.57 H ATOM 3321 HG2 LYS B 432 17.307 -63.036 35.185 1.00 18.03 H ATOM 3322 HG3 LYS B 432 16.514 -64.019 36.141 1.00 18.03 H ATOM 3323 HD2 LYS B 432 16.424 -65.624 34.426 1.00 19.90 H ATOM 3324 HD3 LYS B 432 17.223 -64.634 33.463 1.00 19.90 H ATOM 3325 HE2 LYS B 432 19.104 -64.761 34.908 1.00 22.64 H ATOM 3326 HE3 LYS B 432 18.305 -65.772 35.850 1.00 22.64 H ATOM 3327 HZ1 LYS B 432 19.690 -66.883 34.479 1.00 22.99 H ATOM 3328 HZ2 LYS B 432 18.202 -67.237 34.160 1.00 22.99 H ATOM 3329 HZ3 LYS B 432 18.984 -66.246 33.238 1.00 22.99 H ATOM 3330 N ASN B 433 13.131 -63.734 37.163 1.00 11.70 N ANISOU 3330 N ASN B 433 1676 1474 1295 289 -177 -84 N ATOM 3331 CA ASN B 433 12.843 -64.121 38.524 1.00 12.79 C ANISOU 3331 CA ASN B 433 1922 1651 1289 281 -255 3 C ATOM 3332 C ASN B 433 11.611 -65.047 38.633 1.00 12.27 C ANISOU 3332 C ASN B 433 2169 1551 943 98 -102 15 C ATOM 3333 O ASN B 433 11.100 -65.260 39.723 1.00 13.61 O ANISOU 3333 O ASN B 433 2024 1987 1161 332 -162 -89 O ATOM 3334 CB ASN B 433 12.617 -62.895 39.368 1.00 15.62 C ANISOU 3334 CB ASN B 433 2256 2214 1465 537 -139 -47 C ATOM 3335 CG ASN B 433 12.687 -63.167 40.826 1.00 22.97 C ANISOU 3335 CG ASN B 433 3008 3094 2626 -34 -78 355 C ATOM 3336 OD1 ASN B 433 13.562 -63.935 41.281 1.00 25.47 O ANISOU 3336 OD1 ASN B 433 3536 3999 2142 -334 -380 319 O ATOM 3337 ND2 ASN B 433 11.782 -62.540 41.602 1.00 22.22 N ANISOU 3337 ND2 ASN B 433 3543 3107 1793 -92 -687 313 N ATOM 3338 H ASN B 433 12.762 -62.992 36.933 1.00 14.05 H ATOM 3339 HA ASN B 433 13.615 -64.601 38.889 1.00 15.37 H ATOM 3340 HB2 ASN B 433 13.296 -62.235 39.155 1.00 18.76 H ATOM 3341 HB3 ASN B 433 11.736 -62.537 39.174 1.00 18.76 H ATOM 3342 HD21 ASN B 433 11.784 -62.684 42.571 1.00 26.68 H ATOM 3343 HD22 ASN B 433 11.122 -61.940 41.197 1.00 26.68 H ATOM 3344 N GLN B 434 11.173 -65.584 37.502 1.00 11.53 N ANISOU 3344 N GLN B 434 1657 1459 1267 104 -72 -122 N ATOM 3345 CA GLN B 434 10.107 -66.596 37.453 1.00 11.63 C ANISOU 3345 CA GLN B 434 1658 1485 1274 112 77 -111 C ATOM 3346 C GLN B 434 8.757 -66.014 37.832 1.00 11.31 C ANISOU 3346 C GLN B 434 1760 1353 1183 106 215 -250 C ATOM 3347 O GLN B 434 7.876 -66.764 38.199 1.00 15.94 O ANISOU 3347 O GLN B 434 1744 1461 2851 -31 522 -516 O ATOM 3348 CB GLN B 434 10.411 -67.906 38.210 1.00 12.86 C ANISOU 3348 CB GLN B 434 1984 1474 1430 20 44 -105 C ATOM 3349 CG GLN B 434 11.711 -68.546 37.657 1.00 13.05 C ANISOU 3349 CG GLN B 434 1952 1529 1475 -20 -85 -2 C ATOM 3350 CD GLN B 434 12.076 -69.874 38.277 1.00 13.67 C ANISOU 3350 CD GLN B 434 2190 1537 1467 -97 -22 164 C ATOM 3351 OE1 GLN B 434 12.586 -70.788 37.610 1.00 15.46 O ANISOU 3351 OE1 GLN B 434 2400 1586 1888 -213 -223 56 O ATOM 3352 NE2 GLN B 434 11.870 -69.995 39.568 1.00 15.57 N ANISOU 3352 NE2 GLN B 434 2701 1664 1551 -249 -293 -48 N ATOM 3353 H GLN B 434 11.481 -65.375 36.726 1.00 13.86 H ATOM 3354 HA GLN B 434 10.022 -66.856 36.512 1.00 13.97 H ATOM 3355 HB2 GLN B 434 10.537 -67.715 39.153 1.00 15.45 H ATOM 3356 HB3 GLN B 434 9.681 -68.532 38.083 1.00 15.45 H ATOM 3357 HG2 GLN B 434 11.605 -68.685 36.703 1.00 15.67 H ATOM 3358 HG3 GLN B 434 12.448 -67.934 37.817 1.00 15.67 H ATOM 3359 HE21 GLN B 434 12.062 -70.732 39.967 1.00 18.70 H ATOM 3360 HE22 GLN B 434 11.543 -69.335 40.014 1.00 18.70 H ATOM 3361 N GLU B 435 8.568 -64.697 37.642 1.00 10.87 N ANISOU 3361 N GLU B 435 1705 1228 1196 0 43 20 N ATOM 3362 CA GLU B 435 7.314 -64.019 37.967 1.00 10.96 C ANISOU 3362 CA GLU B 435 1901 1203 1059 37 207 110 C ATOM 3363 C GLU B 435 6.599 -63.581 36.728 1.00 9.68 C ANISOU 3363 C GLU B 435 1666 1021 991 70 232 -22 C ATOM 3364 O GLU B 435 7.225 -63.206 35.737 1.00 10.58 O ANISOU 3364 O GLU B 435 1524 1374 1120 17 269 -107 O ATOM 3365 CB GLU B 435 7.578 -62.783 38.827 1.00 13.69 C ANISOU 3365 CB GLU B 435 2222 1667 1312 62 -143 133 C ATOM 3366 CG GLU B 435 8.147 -63.137 40.178 1.00 14.83 C ANISOU 3366 CG GLU B 435 2354 1752 1530 46 -120 338 C ATOM 3367 CD GLU B 435 8.542 -61.983 41.074 1.00 16.96 C ANISOU 3367 CD GLU B 435 2898 2155 1390 139 388 185 C ATOM 3368 OE1 GLU B 435 9.298 -61.101 40.690 1.00 15.69 O ANISOU 3368 OE1 GLU B 435 2465 2118 1380 61 30 130 O ATOM 3369 OE2 GLU B 435 8.144 -61.999 42.246 1.00 21.83 O ANISOU 3369 OE2 GLU B 435 3886 2533 1876 528 330 449 O ATOM 3370 H GLU B 435 9.167 -64.171 37.320 1.00 13.06 H ATOM 3371 HA GLU B 435 6.731 -64.629 38.466 1.00 13.16 H ATOM 3372 HB2 GLU B 435 8.215 -62.209 38.373 1.00 16.44 H ATOM 3373 HB3 GLU B 435 6.743 -62.309 38.967 1.00 16.44 H ATOM 3374 HG2 GLU B 435 7.485 -63.659 40.658 1.00 17.81 H ATOM 3375 HG3 GLU B 435 8.941 -63.678 40.039 1.00 17.81 H ATOM 3376 N TRP B 436 5.274 -63.617 36.735 1.00 9.78 N ANISOU 3376 N TRP B 436 1477 1174 1063 134 334 -26 N ATOM 3377 CA TRP B 436 4.479 -63.272 35.549 1.00 9.30 C ANISOU 3377 CA TRP B 436 1404 1198 931 57 197 -44 C ATOM 3378 C TRP B 436 4.316 -61.764 35.448 1.00 9.67 C ANISOU 3378 C TRP B 436 1391 1078 1205 -16 289 128 C ATOM 3379 O TRP B 436 3.678 -61.162 36.318 1.00 11.82 O ANISOU 3379 O TRP B 436 1923 1108 1459 -112 630 -25 O ATOM 3380 CB TRP B 436 3.104 -63.950 35.597 1.00 10.53 C ANISOU 3380 CB TRP B 436 1566 1250 1185 -131 320 -218 C ATOM 3381 CG TRP B 436 3.167 -65.450 35.468 1.00 10.03 C ANISOU 3381 CG TRP B 436 1399 1200 1212 53 142 -226 C ATOM 3382 CD1 TRP B 436 2.785 -66.392 36.383 1.00 11.90 C ANISOU 3382 CD1 TRP B 436 1785 1342 1394 54 192 -1 C ATOM 3383 CD2 TRP B 436 3.688 -66.188 34.365 1.00 9.74 C ANISOU 3383 CD2 TRP B 436 1378 1090 1235 163 -105 -254 C ATOM 3384 NE1 TRP B 436 3.033 -67.656 35.934 1.00 12.06 N ANISOU 3384 NE1 TRP B 436 1924 1326 1333 311 -66 -201 N ATOM 3385 CE2 TRP B 436 3.596 -67.570 34.689 1.00 10.71 C ANISOU 3385 CE2 TRP B 436 1598 1421 1052 189 -80 3 C ATOM 3386 CE3 TRP B 436 4.187 -65.850 33.105 1.00 9.23 C ANISOU 3386 CE3 TRP B 436 1208 1159 1141 0 37 -77 C ATOM 3387 CZ2 TRP B 436 3.974 -68.569 33.799 1.00 10.82 C ANISOU 3387 CZ2 TRP B 436 1504 1228 1379 100 -320 29 C ATOM 3388 CZ3 TRP B 436 4.600 -66.832 32.247 1.00 9.66 C ANISOU 3388 CZ3 TRP B 436 1071 1080 1519 29 -223 -89 C ATOM 3389 CH2 TRP B 436 4.509 -68.192 32.587 1.00 10.50 C ANISOU 3389 CH2 TRP B 436 1241 1391 1356 -55 -104 19 C ATOM 3390 H TRP B 436 4.801 -63.840 37.417 1.00 11.75 H ATOM 3391 HA TRP B 436 4.946 -63.583 34.745 1.00 11.17 H ATOM 3392 HB2 TRP B 436 2.682 -63.742 36.446 1.00 12.65 H ATOM 3393 HB3 TRP B 436 2.561 -63.610 34.868 1.00 12.65 H ATOM 3394 HD1 TRP B 436 2.439 -66.194 37.223 1.00 14.29 H ATOM 3395 HE1 TRP B 436 2.869 -68.382 36.362 1.00 14.49 H ATOM 3396 HE3 TRP B 436 4.288 -64.956 32.869 1.00 11.09 H ATOM 3397 HZ2 TRP B 436 3.870 -69.466 34.017 1.00 13.00 H ATOM 3398 HZ3 TRP B 436 4.957 -66.595 31.422 1.00 11.60 H ATOM 3399 HH2 TRP B 436 4.777 -68.840 31.978 1.00 12.61 H ATOM 3400 N LEU B 437 4.806 -61.157 34.361 1.00 8.66 N ANISOU 3400 N LEU B 437 1277 974 1041 33 141 -25 N ATOM 3401 CA LEU B 437 4.672 -59.770 34.112 1.00 8.73 C ANISOU 3401 CA LEU B 437 1289 903 1124 -21 166 66 C ATOM 3402 C LEU B 437 3.749 -59.549 32.943 1.00 8.27 C ANISOU 3402 C LEU B 437 1203 879 1058 122 252 57 C ATOM 3403 O LEU B 437 3.891 -60.226 31.910 1.00 9.50 O ANISOU 3403 O LEU B 437 1458 1066 1087 -172 214 98 O ATOM 3404 CB LEU B 437 6.033 -59.127 33.750 1.00 9.16 C ANISOU 3404 CB LEU B 437 1219 1017 1243 132 167 -12 C ATOM 3405 CG LEU B 437 7.093 -59.291 34.848 1.00 11.55 C ANISOU 3405 CG LEU B 437 1348 1357 1683 127 -22 117 C ATOM 3406 CD1 LEU B 437 8.373 -58.612 34.405 1.00 13.74 C ANISOU 3406 CD1 LEU B 437 1688 1439 2095 136 -204 19 C ATOM 3407 CD2 LEU B 437 6.604 -58.758 36.203 1.00 14.53 C ANISOU 3407 CD2 LEU B 437 1758 2063 1699 -124 -90 280 C ATOM 3408 H LEU B 437 5.235 -61.570 33.741 1.00 10.41 H ATOM 3409 HA LEU B 437 4.304 -59.319 34.900 1.00 10.49 H ATOM 3410 HB2 LEU B 437 6.372 -59.543 32.942 1.00 11.00 H ATOM 3411 HB3 LEU B 437 5.902 -58.177 33.602 1.00 11.00 H ATOM 3412 HG LEU B 437 7.283 -60.236 34.956 1.00 13.87 H ATOM 3413 HD11 LEU B 437 9.035 -58.716 35.092 1.00 16.51 H ATOM 3414 HD12 LEU B 437 8.678 -59.022 33.592 1.00 16.51 H ATOM 3415 HD13 LEU B 437 8.197 -57.681 34.257 1.00 16.51 H ATOM 3416 HD21 LEU B 437 7.297 -58.881 36.856 1.00 17.45 H ATOM 3417 HD22 LEU B 437 6.400 -57.824 36.115 1.00 17.45 H ATOM 3418 HD23 LEU B 437 5.818 -59.242 36.464 1.00 17.45 H ATOM 3419 N TRP B 438 2.819 -58.609 33.051 1.00 8.14 N ANISOU 3419 N TRP B 438 1213 890 989 -3 296 61 N ATOM 3420 CA TRP B 438 1.920 -58.325 31.918 1.00 8.58 C ANISOU 3420 CA TRP B 438 1206 992 1061 -11 354 -101 C ATOM 3421 C TRP B 438 2.706 -57.535 30.869 1.00 8.39 C ANISOU 3421 C TRP B 438 1113 1061 1014 104 229 171 C ATOM 3422 O TRP B 438 3.302 -56.471 31.144 1.00 8.99 O ANISOU 3422 O TRP B 438 1410 957 1050 204 364 176 O ATOM 3423 CB TRP B 438 0.725 -57.527 32.363 1.00 9.28 C ANISOU 3423 CB TRP B 438 1214 1082 1231 -50 314 -181 C ATOM 3424 CG TRP B 438 -0.327 -58.374 32.971 1.00 9.09 C ANISOU 3424 CG TRP B 438 1142 1087 1224 -67 292 -109 C ATOM 3425 CD1 TRP B 438 -0.642 -58.474 34.298 1.00 10.90 C ANISOU 3425 CD1 TRP B 438 1383 1546 1214 -17 280 -259 C ATOM 3426 CD2 TRP B 438 -1.207 -59.267 32.260 1.00 9.71 C ANISOU 3426 CD2 TRP B 438 1062 1055 1573 12 160 -197 C ATOM 3427 NE1 TRP B 438 -1.659 -59.397 34.435 1.00 11.64 N ANISOU 3427 NE1 TRP B 438 1386 1492 1544 -45 671 -373 N ATOM 3428 CE2 TRP B 438 -2.036 -59.868 33.194 1.00 11.22 C ANISOU 3428 CE2 TRP B 438 1300 1154 1810 -13 402 -233 C ATOM 3429 CE3 TRP B 438 -1.380 -59.589 30.916 1.00 11.43 C ANISOU 3429 CE3 TRP B 438 1536 1161 1647 -21 170 66 C ATOM 3430 CZ2 TRP B 438 -3.029 -60.782 32.826 1.00 13.86 C ANISOU 3430 CZ2 TRP B 438 1299 1457 2509 46 491 -586 C ATOM 3431 CZ3 TRP B 438 -2.369 -60.511 30.592 1.00 13.82 C ANISOU 3431 CZ3 TRP B 438 1587 1412 2251 -76 -140 126 C ATOM 3432 CH2 TRP B 438 -3.158 -61.079 31.513 1.00 15.86 C ANISOU 3432 CH2 TRP B 438 1686 1386 2952 -157 195 -162 C ATOM 3433 H TRP B 438 2.683 -58.124 33.749 1.00 9.78 H ATOM 3434 HA TRP B 438 1.611 -59.165 31.519 1.00 10.31 H ATOM 3435 HB2 TRP B 438 1.006 -56.876 33.025 1.00 11.15 H ATOM 3436 HB3 TRP B 438 0.341 -57.075 31.595 1.00 11.15 H ATOM 3437 HD1 TRP B 438 -0.220 -58.022 34.993 1.00 13.10 H ATOM 3438 HE1 TRP B 438 -2.035 -59.608 35.178 1.00 13.98 H ATOM 3439 HE3 TRP B 438 -0.850 -59.202 30.258 1.00 13.74 H ATOM 3440 HZ2 TRP B 438 -3.582 -61.173 33.464 1.00 16.64 H ATOM 3441 HZ3 TRP B 438 -2.495 -60.733 29.698 1.00 16.59 H ATOM 3442 HH2 TRP B 438 -3.804 -61.692 31.246 1.00 19.04 H ATOM 3443 N AMET B 439 2.692 -58.051 29.662 0.53 8.65 N ANISOU 3443 N AMET B 439 1332 859 1095 311 169 -40 N ATOM 3444 N BMET B 439 2.594 -58.054 29.666 0.47 7.99 N ANISOU 3444 N BMET B 439 1002 1092 941 91 291 186 N ATOM 3445 CA AMET B 439 3.315 -57.399 28.510 0.53 8.66 C ANISOU 3445 CA AMET B 439 1068 1127 1096 392 119 22 C ATOM 3446 CA BMET B 439 3.246 -57.495 28.484 0.47 8.95 C ANISOU 3446 CA BMET B 439 1078 1299 1025 195 332 163 C ATOM 3447 C AMET B 439 2.290 -57.133 27.424 0.53 9.38 C ANISOU 3447 C AMET B 439 1238 1177 1151 312 290 185 C ATOM 3448 C BMET B 439 2.157 -57.070 27.489 0.47 8.73 C ANISOU 3448 C BMET B 439 1205 1143 970 429 68 9 C ATOM 3449 O AMET B 439 1.507 -58.017 27.083 0.53 9.43 O ANISOU 3449 O AMET B 439 1171 1420 991 290 110 -96 O ATOM 3450 O BMET B 439 1.154 -57.740 27.327 0.47 10.18 O ANISOU 3450 O BMET B 439 1214 1049 1604 81 427 -50 O ATOM 3451 CB AMET B 439 4.362 -58.303 27.900 0.53 10.31 C ANISOU 3451 CB AMET B 439 1405 1179 1334 201 138 154 C ATOM 3452 CB BMET B 439 4.198 -58.535 27.876 0.47 9.77 C ANISOU 3452 CB BMET B 439 1096 1449 1167 -7 447 32 C ATOM 3453 CG AMET B 439 5.424 -58.697 28.836 0.53 11.24 C ANISOU 3453 CG AMET B 439 1480 1158 1634 -50 472 90 C ATOM 3454 CG BMET B 439 5.283 -58.003 26.948 0.47 11.43 C ANISOU 3454 CG BMET B 439 1393 1543 1405 -348 360 -149 C ATOM 3455 SD AMET B 439 6.445 -57.361 29.448 0.53 11.48 S ANISOU 3455 SD AMET B 439 1485 1535 1343 -10 234 186 S ATOM 3456 SD BMET B 439 6.527 -56.959 27.873 0.47 16.29 S ANISOU 3456 SD BMET B 439 2107 1541 2541 259 429 85 S ATOM 3457 CE AMET B 439 7.414 -56.886 27.989 0.53 17.10 C ANISOU 3457 CE AMET B 439 2160 2235 2103 -36 144 -324 C ATOM 3458 CE BMET B 439 7.620 -58.264 28.473 0.47 21.12 C ANISOU 3458 CE BMET B 439 2479 2554 2993 474 2 -268 C ATOM 3459 H AMET B 439 2.320 -58.801 29.468 0.53 10.39 H ATOM 3460 H BMET B 439 2.130 -58.758 29.495 0.47 9.60 H ATOM 3461 HA AMET B 439 3.739 -56.558 28.786 0.53 10.41 H ATOM 3462 HA BMET B 439 3.772 -56.711 28.744 0.47 10.76 H ATOM 3463 HB2AMET B 439 3.930 -59.112 27.584 0.53 12.39 H ATOM 3464 HB2BMET B 439 4.643 -59.000 28.602 0.47 11.74 H ATOM 3465 HB3AMET B 439 4.779 -57.843 27.156 0.53 12.39 H ATOM 3466 HB3BMET B 439 3.669 -59.168 27.366 0.47 11.74 H ATOM 3467 HG2AMET B 439 5.013 -59.124 29.604 0.53 13.51 H ATOM 3468 HG2BMET B 439 5.754 -58.750 26.545 0.47 13.73 H ATOM 3469 HG3AMET B 439 6.008 -59.330 28.389 0.53 13.51 H ATOM 3470 HG3BMET B 439 4.876 -57.454 26.261 0.47 13.73 H ATOM 3471 HE1AMET B 439 8.001 -56.163 28.225 0.53 20.54 H ATOM 3472 HE1BMET B 439 8.330 -57.865 28.982 0.47 25.36 H ATOM 3473 HE2AMET B 439 7.928 -57.642 27.696 0.53 20.54 H ATOM 3474 HE2BMET B 439 7.116 -58.862 29.028 0.47 25.36 H ATOM 3475 HE3AMET B 439 6.815 -56.607 27.293 0.53 20.54 H ATOM 3476 HE3BMET B 439 7.982 -58.737 27.722 0.47 25.36 H ATOM 3477 N ARG B 440 2.351 -55.943 26.848 1.00 9.32 N ANISOU 3477 N ARG B 440 1379 1192 973 272 253 4 N ATOM 3478 CA ARG B 440 1.639 -55.633 25.636 1.00 10.03 C ANISOU 3478 CA ARG B 440 1411 1443 956 197 222 -49 C ATOM 3479 C ARG B 440 2.656 -55.634 24.530 1.00 9.84 C ANISOU 3479 C ARG B 440 1509 1355 873 446 157 -68 C ATOM 3480 O ARG B 440 3.623 -54.821 24.515 1.00 11.07 O ANISOU 3480 O ARG B 440 1561 1554 1091 537 244 45 O ATOM 3481 CB ARG B 440 0.943 -54.282 25.685 1.00 11.89 C ANISOU 3481 CB ARG B 440 1873 1451 1192 -56 195 -143 C ATOM 3482 CG ARG B 440 0.137 -54.058 24.447 1.00 15.34 C ANISOU 3482 CG ARG B 440 2513 1927 1390 -128 172 -325 C ATOM 3483 CD ARG B 440 -0.639 -52.807 24.508 1.00 19.13 C ANISOU 3483 CD ARG B 440 2761 2438 2070 -165 119 -508 C ATOM 3484 NE ARG B 440 -1.737 -52.974 25.467 1.00 25.18 N ANISOU 3484 NE ARG B 440 3028 3387 3154 -653 -71 -1207 N ATOM 3485 CZ ARG B 440 -1.835 -52.380 26.680 1.00 31.63 C ANISOU 3485 CZ ARG B 440 3621 3756 4642 -268 -223 -653 C ATOM 3486 NH1 ARG B 440 -0.936 -51.506 27.093 1.00 34.69 N ANISOU 3486 NH1 ARG B 440 4351 4175 4654 -4 -500 -237 N ATOM 3487 NH2 ARG B 440 -2.866 -52.627 27.503 1.00 32.25 N ANISOU 3487 NH2 ARG B 440 4025 4060 4169 -241 714 -211 N ATOM 3488 H AARG B 440 2.813 -55.285 27.154 0.53 11.20 H ATOM 3489 H BARG B 440 2.899 -55.330 27.099 0.47 11.20 H ATOM 3490 HA ARG B 440 0.972 -56.327 25.454 1.00 12.05 H ATOM 3491 HB2 ARG B 440 0.346 -54.254 26.448 1.00 14.28 H ATOM 3492 HB3 ARG B 440 1.608 -53.578 25.749 1.00 14.28 H ATOM 3493 HG2 ARG B 440 0.734 -54.006 23.684 1.00 18.43 H ATOM 3494 HG3 ARG B 440 -0.484 -54.794 24.335 1.00 18.43 H ATOM 3495 HD2 ARG B 440 -0.070 -52.082 24.809 1.00 22.97 H ATOM 3496 HD3 ARG B 440 -1.014 -52.612 23.635 1.00 22.97 H ATOM 3497 HE ARG B 440 -2.461 -53.566 25.207 1.00 30.23 H ATOM 3498 HH11 ARG B 440 -0.255 -51.324 26.601 1.00 41.64 H ATOM 3499 HH12 ARG B 440 -1.021 -51.132 27.863 1.00 41.64 H ATOM 3500 HH21 ARG B 440 -3.482 -53.178 27.268 1.00 38.72 H ATOM 3501 HH22 ARG B 440 -2.919 -52.220 28.259 1.00 38.72 H ATOM 3502 N THR B 441 2.479 -56.532 23.576 1.00 10.79 N ANISOU 3502 N THR B 441 1443 1635 1022 506 385 167 N ATOM 3503 CA THR B 441 3.347 -56.644 22.416 1.00 11.04 C ANISOU 3503 CA THR B 441 1401 1670 1126 561 230 101 C ATOM 3504 C THR B 441 2.618 -56.088 21.202 1.00 10.68 C ANISOU 3504 C THR B 441 1199 1749 1109 363 312 -6 C ATOM 3505 O THR B 441 1.509 -56.550 20.882 1.00 12.87 O ANISOU 3505 O THR B 441 1347 2285 1257 728 149 -125 O ATOM 3506 CB THR B 441 3.804 -58.083 22.220 1.00 12.76 C ANISOU 3506 CB THR B 441 1452 1972 1424 438 -27 148 C ATOM 3507 OG1 THR B 441 4.676 -58.441 23.304 1.00 14.55 O ANISOU 3507 OG1 THR B 441 1642 2121 1768 232 367 -39 O ATOM 3508 CG2 THR B 441 4.489 -58.281 20.882 1.00 14.63 C ANISOU 3508 CG2 THR B 441 1923 2296 1342 209 459 91 C ATOM 3509 H THR B 441 1.840 -57.107 23.579 1.00 12.96 H ATOM 3510 HA THR B 441 4.145 -56.093 22.564 1.00 13.27 H ATOM 3511 HB THR B 441 3.027 -58.662 22.242 1.00 15.32 H ATOM 3512 HG1 THR B 441 5.328 -57.944 23.315 1.00 17.48 H ATOM 3513 HG21 THR B 441 4.766 -59.195 20.788 1.00 17.58 H ATOM 3514 HG22 THR B 441 3.885 -58.062 20.169 1.00 17.58 H ATOM 3515 HG23 THR B 441 5.262 -57.714 20.822 1.00 17.58 H ATOM 3516 N SER B 442 3.206 -55.095 20.558 1.00 10.26 N ANISOU 3516 N SER B 442 1276 1543 1081 465 305 47 N ATOM 3517 CA SER B 442 2.696 -54.554 19.315 1.00 10.07 C ANISOU 3517 CA SER B 442 1201 1382 1244 278 266 -60 C ATOM 3518 C SER B 442 3.586 -55.047 18.188 1.00 9.42 C ANISOU 3518 C SER B 442 1063 1499 1016 356 262 -105 C ATOM 3519 O SER B 442 4.770 -54.776 18.245 1.00 10.73 O ANISOU 3519 O SER B 442 993 1888 1196 356 239 -32 O ATOM 3520 CB SER B 442 2.712 -53.053 19.399 1.00 13.65 C ANISOU 3520 CB SER B 442 1620 1583 1982 9 424 20 C ATOM 3521 OG SER B 442 1.825 -52.630 20.470 1.00 20.94 O ANISOU 3521 OG SER B 442 2605 1956 3397 -216 1032 539 O ATOM 3522 H SER B 442 3.922 -54.706 20.831 1.00 12.33 H ATOM 3523 HA SER B 442 1.778 -54.862 19.161 1.00 12.10 H ATOM 3524 HB2 SER B 442 3.614 -52.752 19.590 1.00 16.39 H ATOM 3525 HB3 SER B 442 2.402 -52.681 18.559 1.00 16.39 H ATOM 3526 HG SER B 442 1.825 -51.812 20.526 1.00 25.15 H ATOM 3527 N ASER B 443 3.000 -55.778 17.238 0.53 10.05 N ANISOU 3527 N ASER B 443 1125 1492 1200 158 69 96 N ATOM 3528 N BSER B 443 3.017 -55.794 17.257 0.47 9.90 N ANISOU 3528 N BSER B 443 1155 1496 1110 204 69 65 N ATOM 3529 CA ASER B 443 3.761 -56.514 16.234 0.53 10.32 C ANISOU 3529 CA ASER B 443 1372 1614 933 68 60 -59 C ATOM 3530 CA BSER B 443 3.801 -56.463 16.243 0.47 10.08 C ANISOU 3530 CA BSER B 443 1335 1682 813 -111 80 81 C ATOM 3531 C ASER B 443 3.321 -56.194 14.813 0.53 9.77 C ANISOU 3531 C ASER B 443 971 1446 1296 283 262 -453 C ATOM 3532 C BSER B 443 3.376 -55.983 14.877 0.47 10.54 C ANISOU 3532 C BSER B 443 1212 1737 1056 -283 22 431 C ATOM 3533 O ASER B 443 2.133 -56.002 14.532 0.53 8.72 O ANISOU 3533 O ASER B 443 760 1296 1256 92 114 -113 O ATOM 3534 O BSER B 443 2.232 -55.526 14.706 0.47 10.55 O ANISOU 3534 O BSER B 443 1373 1521 1115 161 34 -125 O ATOM 3535 CB ASER B 443 3.572 -58.026 16.444 0.53 11.31 C ANISOU 3535 CB ASER B 443 1590 1603 1106 67 -13 8 C ATOM 3536 CB BSER B 443 3.535 -57.983 16.313 0.47 10.09 C ANISOU 3536 CB BSER B 443 1326 1571 935 -175 -161 -265 C ATOM 3537 OG ASER B 443 2.257 -58.431 16.115 0.53 12.76 O ANISOU 3537 OG ASER B 443 2043 1543 1261 -7 25 -176 O ATOM 3538 OG BSER B 443 3.809 -58.481 17.610 0.47 11.77 O ANISOU 3538 OG BSER B 443 1340 1696 1436 -190 315 -246 O ATOM 3539 H ASER B 443 2.148 -55.861 17.154 0.54 12.07 H ATOM 3540 H BSER B 443 2.170 -55.930 17.192 0.46 11.89 H ATOM 3541 HA ASER B 443 4.714 -56.303 16.322 0.54 12.40 H ATOM 3542 HA BSER B 443 4.757 -56.290 16.373 0.46 12.11 H ATOM 3543 HB2ASER B 443 4.199 -58.502 15.878 0.54 13.59 H ATOM 3544 HB2BSER B 443 2.603 -58.150 16.101 0.46 12.12 H ATOM 3545 HB3ASER B 443 3.742 -58.236 17.376 0.54 13.59 H ATOM 3546 HB3BSER B 443 4.108 -58.434 15.674 0.46 12.12 H ATOM 3547 HG ASER B 443 1.818 -57.784 15.867 0.54 15.32 H ATOM 3548 HG BSER B 443 4.062 -57.871 18.096 0.46 14.14 H ATOM 3549 N PHE B 444 4.271 -56.130 13.900 1.00 10.47 N ANISOU 3549 N PHE B 444 1124 1759 1095 19 32 -160 N ATOM 3550 CA PHE B 444 3.941 -55.938 12.483 1.00 11.37 C ANISOU 3550 CA PHE B 444 1396 1938 986 3 57 -328 C ATOM 3551 C PHE B 444 5.000 -56.648 11.659 1.00 11.36 C ANISOU 3551 C PHE B 444 1434 1881 1002 -66 -26 -420 C ATOM 3552 O PHE B 444 6.091 -56.868 12.114 1.00 11.13 O ANISOU 3552 O PHE B 444 1588 1662 980 -136 50 -211 O ATOM 3553 CB PHE B 444 3.845 -54.451 12.102 1.00 12.71 C ANISOU 3553 CB PHE B 444 1481 1821 1528 -58 228 -455 C ATOM 3554 CG PHE B 444 5.084 -53.672 12.352 1.00 14.70 C ANISOU 3554 CG PHE B 444 1928 1527 2129 -225 440 -451 C ATOM 3555 CD1 PHE B 444 5.348 -53.081 13.565 1.00 16.69 C ANISOU 3555 CD1 PHE B 444 1989 1684 2667 7 400 -214 C ATOM 3556 CD2 PHE B 444 6.019 -53.515 11.329 1.00 16.19 C ANISOU 3556 CD2 PHE B 444 2235 1871 2046 -108 636 -685 C ATOM 3557 CE1 PHE B 444 6.518 -52.319 13.737 1.00 18.02 C ANISOU 3557 CE1 PHE B 444 2430 1498 2920 26 514 -414 C ATOM 3558 CE2 PHE B 444 7.183 -52.763 11.539 1.00 19.70 C ANISOU 3558 CE2 PHE B 444 2205 2159 3121 57 1037 -663 C ATOM 3559 CZ PHE B 444 7.441 -52.217 12.732 1.00 18.69 C ANISOU 3559 CZ PHE B 444 1989 1829 3281 124 230 -720 C ATOM 3560 H APHE B 444 5.112 -56.194 14.064 0.53 12.58 H ATOM 3561 H BPHE B 444 5.092 -56.345 14.034 0.47 12.58 H ATOM 3562 HA PHE B 444 3.075 -56.358 12.294 1.00 13.66 H ATOM 3563 HB2 PHE B 444 3.641 -54.386 11.156 1.00 15.27 H ATOM 3564 HB3 PHE B 444 3.132 -54.044 12.619 1.00 15.27 H ATOM 3565 HD1 PHE B 444 4.736 -53.158 14.261 1.00 20.04 H ATOM 3566 HD2 PHE B 444 5.866 -53.905 10.499 1.00 19.45 H ATOM 3567 HE1 PHE B 444 6.698 -51.937 14.565 1.00 21.64 H ATOM 3568 HE2 PHE B 444 7.805 -52.678 10.853 1.00 23.65 H ATOM 3569 HZ PHE B 444 8.212 -51.711 12.856 1.00 22.44 H ATOM 3570 N THR B 445 4.642 -57.005 10.412 1.00 13.64 N ANISOU 3570 N THR B 445 1535 2479 1167 -172 30 -465 N ATOM 3571 CA THR B 445 5.636 -57.688 9.558 1.00 13.73 C ANISOU 3571 CA THR B 445 1567 2522 1129 -487 554 -450 C ATOM 3572 C THR B 445 6.467 -56.688 8.742 1.00 14.47 C ANISOU 3572 C THR B 445 2233 2250 1016 -740 238 -374 C ATOM 3573 O THR B 445 6.034 -55.525 8.495 1.00 17.97 O ANISOU 3573 O THR B 445 3028 2476 1324 -981 877 -526 O ATOM 3574 CB THR B 445 4.949 -58.575 8.548 1.00 16.44 C ANISOU 3574 CB THR B 445 2031 2764 1451 -278 -134 -644 C ATOM 3575 OG1 THR B 445 3.980 -57.790 7.828 1.00 17.20 O ANISOU 3575 OG1 THR B 445 2094 2863 1579 -148 142 -344 O ATOM 3576 CG2 THR B 445 4.274 -59.700 9.231 1.00 18.90 C ANISOU 3576 CG2 THR B 445 2166 2487 2527 -187 265 -382 C ATOM 3577 H THR B 445 3.873 -56.871 10.052 1.00 16.38 H ATOM 3578 HA THR B 445 6.237 -58.233 10.108 1.00 16.50 H ATOM 3579 HB THR B 445 5.604 -58.936 7.929 1.00 19.74 H ATOM 3580 HG1 THR B 445 3.597 -58.257 7.274 1.00 20.66 H ATOM 3581 HG21 THR B 445 3.838 -60.261 8.586 1.00 22.69 H ATOM 3582 HG22 THR B 445 4.916 -60.223 9.717 1.00 22.69 H ATOM 3583 HG23 THR B 445 3.617 -59.362 9.845 1.00 22.69 H ATOM 3584 N PHE B 446 7.638 -57.100 8.349 1.00 13.92 N ANISOU 3584 N PHE B 446 2032 1998 1259 -458 423 -455 N ATOM 3585 CA PHE B 446 8.409 -56.351 7.412 1.00 13.58 C ANISOU 3585 CA PHE B 446 2463 1555 1143 -100 480 -124 C ATOM 3586 C PHE B 446 9.160 -57.301 6.502 1.00 11.92 C ANISOU 3586 C PHE B 446 2138 1453 937 294 162 -125 C ATOM 3587 O PHE B 446 9.593 -58.361 6.901 1.00 12.03 O ANISOU 3587 O PHE B 446 1973 1468 1130 69 215 -70 O ATOM 3588 CB PHE B 446 9.447 -55.462 8.134 1.00 15.34 C ANISOU 3588 CB PHE B 446 2855 1775 1199 -264 500 320 C ATOM 3589 CG PHE B 446 10.280 -54.682 7.156 1.00 15.55 C ANISOU 3589 CG PHE B 446 3516 1548 846 551 618 186 C ATOM 3590 CD1 PHE B 446 9.813 -53.497 6.636 1.00 18.38 C ANISOU 3590 CD1 PHE B 446 3860 1670 1453 612 303 -108 C ATOM 3591 CD2 PHE B 446 11.542 -55.111 6.791 1.00 16.97 C ANISOU 3591 CD2 PHE B 446 2962 2001 1484 1003 314 516 C ATOM 3592 CE1 PHE B 446 10.592 -52.798 5.681 1.00 19.99 C ANISOU 3592 CE1 PHE B 446 3582 1883 2132 998 -344 1 C ATOM 3593 CE2 PHE B 446 12.312 -54.392 5.899 1.00 19.72 C ANISOU 3593 CE2 PHE B 446 3648 2170 1675 1076 133 772 C ATOM 3594 CZ PHE B 446 11.839 -53.257 5.396 1.00 20.02 C ANISOU 3594 CZ PHE B 446 3667 2013 1926 1092 -127 -14 C ATOM 3595 H PHE B 446 8.015 -57.825 8.617 1.00 16.72 H ATOM 3596 HA PHE B 446 7.823 -55.783 6.869 1.00 16.31 H ATOM 3597 HB2 PHE B 446 8.984 -54.832 8.709 1.00 18.42 H ATOM 3598 HB3 PHE B 446 10.039 -56.023 8.658 1.00 18.42 H ATOM 3599 HD1 PHE B 446 8.958 -53.198 6.849 1.00 22.07 H ATOM 3600 HD2 PHE B 446 11.879 -55.898 7.154 1.00 20.38 H ATOM 3601 HE1 PHE B 446 10.293 -51.992 5.327 1.00 24.01 H ATOM 3602 HE2 PHE B 446 13.159 -54.694 5.662 1.00 23.68 H ATOM 3603 HZ PHE B 446 12.359 -52.788 4.783 1.00 24.04 H ATOM 3604 N AGLN B 447 9.305 -56.934 5.229 0.34 13.83 N ANISOU 3604 N AGLN B 447 2236 1628 1390 219 336 -233 N ATOM 3605 N BGLN B 447 9.335 -56.804 5.273 0.41 12.54 N ANISOU 3605 N BGLN B 447 2389 1601 775 395 279 233 N ATOM 3606 N CGLN B 447 9.318 -56.930 5.240 0.25 13.69 N ANISOU 3606 N CGLN B 447 2198 1642 1363 197 299 -163 N ATOM 3607 CA AGLN B 447 10.356 -57.524 4.387 0.34 14.04 C ANISOU 3607 CA AGLN B 447 2537 1663 1134 -107 482 64 C ATOM 3608 CA BGLN B 447 10.072 -57.480 4.197 0.41 14.94 C ANISOU 3608 CA BGLN B 447 2613 1689 1376 161 530 299 C ATOM 3609 CA CGLN B 447 10.426 -57.470 4.453 0.25 13.76 C ANISOU 3609 CA CGLN B 447 2402 1692 1134 -29 357 130 C ATOM 3610 C AGLN B 447 10.778 -56.459 3.392 0.34 13.94 C ANISOU 3610 C AGLN B 447 2405 1527 1366 5 319 -112 C ATOM 3611 C BGLN B 447 10.787 -56.351 3.410 0.41 12.03 C ANISOU 3611 C BGLN B 447 2347 1440 785 358 343 -286 C ATOM 3612 C CGLN B 447 10.815 -56.391 3.490 0.25 13.61 C ANISOU 3612 C CGLN B 447 2315 1505 1352 107 284 46 C ATOM 3613 O AGLN B 447 9.954 -55.637 2.983 0.34 17.08 O ANISOU 3613 O AGLN B 447 2995 1747 1750 -435 129 431 O ATOM 3614 O BGLN B 447 10.176 -55.328 3.183 0.41 12.50 O ANISOU 3614 O BGLN B 447 2611 1279 858 457 470 -245 O ATOM 3615 O CGLN B 447 10.004 -55.538 3.148 0.25 14.78 O ANISOU 3615 O CGLN B 447 2796 1621 1200 -440 283 304 O ATOM 3616 CB AGLN B 447 9.917 -58.780 3.646 0.34 14.96 C ANISOU 3616 CB AGLN B 447 2229 1955 1500 -368 256 379 C ATOM 3617 CB BGLN B 447 9.116 -58.232 3.259 0.41 18.30 C ANISOU 3617 CB BGLN B 447 2492 2154 2308 86 131 -150 C ATOM 3618 CB CGLN B 447 10.084 -58.716 3.663 0.25 14.65 C ANISOU 3618 CB CGLN B 447 2139 1955 1473 -73 197 503 C ATOM 3619 CG AGLN B 447 8.658 -58.648 2.788 0.34 16.28 C ANISOU 3619 CG AGLN B 447 2213 2266 1705 27 -362 -146 C ATOM 3620 CG BGLN B 447 9.773 -58.769 1.944 0.41 17.39 C ANISOU 3620 CG BGLN B 447 2423 2306 1880 45 79 470 C ATOM 3621 CG CGLN B 447 8.973 -58.547 2.644 0.25 18.68 C ANISOU 3621 CG CGLN B 447 2449 2506 2143 -29 -236 294 C ATOM 3622 CD AGLN B 447 9.003 -58.309 1.352 0.34 11.84 C ANISOU 3622 CD AGLN B 447 1920 1683 897 147 -65 -191 C ATOM 3623 CD BGLN B 447 8.752 -59.590 1.069 0.41 18.27 C ANISOU 3623 CD BGLN B 447 2451 2442 2050 -71 138 623 C ATOM 3624 CD CGLN B 447 9.143 -59.501 1.483 0.25 21.88 C ANISOU 3624 CD CGLN B 447 2689 2806 2820 155 -11 76 C ATOM 3625 OE1AGLN B 447 8.597 -57.294 0.854 0.34 11.64 O ANISOU 3625 OE1AGLN B 447 2116 1322 985 73 -102 211 O ATOM 3626 OE1BGLN B 447 7.768 -59.070 0.584 0.41 20.37 O ANISOU 3626 OE1BGLN B 447 2733 2398 2609 -130 -826 663 O ATOM 3627 OE1CGLN B 447 10.082 -59.383 0.697 0.25 21.14 O ANISOU 3627 OE1CGLN B 447 2649 2885 2496 221 211 -180 O ATOM 3628 NE2AGLN B 447 9.783 -59.148 0.713 0.34 14.23 N ANISOU 3628 NE2AGLN B 447 2348 2161 897 590 -8 -62 N ATOM 3629 NE2BGLN B 447 8.996 -60.863 0.923 0.41 16.46 N ANISOU 3629 NE2BGLN B 447 2108 2638 1509 -212 618 538 N ATOM 3630 NE2CGLN B 447 8.238 -60.453 1.376 0.25 22.68 N ANISOU 3630 NE2CGLN B 447 2763 2866 2990 403 -412 40 N ATOM 3631 H AGLN B 447 8.816 -56.349 4.830 0.33 16.61 H ATOM 3632 H BGLN B 447 9.022 -56.042 5.030 0.41 15.06 H ATOM 3633 H CGLN B 447 8.810 -56.377 4.819 0.26 16.45 H ATOM 3634 HA AGLN B 447 11.129 -57.751 4.944 0.33 16.86 H ATOM 3635 HA BGLN B 447 10.735 -58.100 4.564 0.41 17.95 H ATOM 3636 HA CGLN B 447 11.188 -57.662 5.038 0.26 16.53 H ATOM 3637 HB2AGLN B 447 10.639 -59.057 3.060 0.33 17.96 H ATOM 3638 HB2BGLN B 447 8.752 -58.995 3.736 0.41 21.97 H ATOM 3639 HB2CGLN B 447 10.878 -59.006 3.185 0.26 17.60 H ATOM 3640 HB3AGLN B 447 9.749 -59.478 4.300 0.33 17.96 H ATOM 3641 HB3BGLN B 447 8.397 -57.633 3.005 0.41 21.97 H ATOM 3642 HB3CGLN B 447 9.808 -59.409 4.284 0.26 17.60 H ATOM 3643 HG2AGLN B 447 8.176 -59.489 2.794 0.33 19.54 H ATOM 3644 HG2BGLN B 447 10.088 -58.019 1.416 0.41 20.89 H ATOM 3645 HG2CGLN B 447 8.120 -58.730 3.066 0.26 22.43 H ATOM 3646 HG3AGLN B 447 8.101 -57.938 3.143 0.33 19.54 H ATOM 3647 HG3BGLN B 447 10.514 -59.352 2.172 0.41 20.89 H ATOM 3648 HG3CGLN B 447 8.990 -57.641 2.299 0.26 22.43 H ATOM 3649 HE21AGLN B 447 10.004 -58.993 -0.103 0.33 17.09 H ATOM 3650 HE21BGLN B 447 8.465 -61.351 0.454 0.41 19.77 H ATOM 3651 HE21CGLN B 447 8.287 -61.024 0.734 0.26 27.23 H ATOM 3652 HE22AGLN B 447 10.074 -59.852 1.112 0.33 17.09 H ATOM 3653 HE22BGLN B 447 9.687 -61.213 1.295 0.41 19.77 H ATOM 3654 HE22CGLN B 447 7.599 -60.506 1.949 0.26 27.23 H ATOM 3655 N ASN B 448 12.064 -56.436 3.087 1.00 13.96 N ANISOU 3655 N ASN B 448 2415 1683 1207 157 298 139 N ATOM 3656 CA ASN B 448 12.676 -55.408 2.249 1.00 12.94 C ANISOU 3656 CA ASN B 448 2491 1602 824 146 518 -107 C ATOM 3657 C ASN B 448 11.966 -55.503 0.884 1.00 12.36 C ANISOU 3657 C ASN B 448 2262 1691 742 0 478 -130 C ATOM 3658 O ASN B 448 11.922 -56.567 0.285 1.00 12.07 O ANISOU 3658 O ASN B 448 2232 1325 1031 -19 467 93 O ATOM 3659 CB ASN B 448 14.187 -55.599 2.163 1.00 14.22 C ANISOU 3659 CB ASN B 448 2419 1760 1223 4 271 -12 C ATOM 3660 CG ASN B 448 14.852 -54.517 1.385 1.00 13.62 C ANISOU 3660 CG ASN B 448 2173 1720 1280 211 30 11 C ATOM 3661 OD1 ASN B 448 14.348 -54.118 0.314 1.00 15.68 O ANISOU 3661 OD1 ASN B 448 2614 1893 1451 477 -294 -32 O ATOM 3662 ND2 ASN B 448 16.001 -54.047 1.878 1.00 14.74 N ANISOU 3662 ND2 ASN B 448 2398 1624 1580 -42 -263 85 N ATOM 3663 H AASN B 448 12.626 -57.026 3.363 0.34 16.77 H ATOM 3664 H BASN B 448 12.596 -57.066 3.333 0.41 16.77 H ATOM 3665 H CASN B 448 12.604 -57.075 3.290 0.25 16.77 H ATOM 3666 HA ASN B 448 12.497 -54.525 2.632 1.00 15.54 H ATOM 3667 HB2 ASN B 448 14.559 -55.599 3.058 1.00 17.08 H ATOM 3668 HB3 ASN B 448 14.376 -56.445 1.725 1.00 17.08 H ATOM 3669 HD21 ASN B 448 16.481 -53.334 1.406 1.00 17.71 H ATOM 3670 HD22 ASN B 448 16.364 -54.414 2.711 1.00 17.71 H ATOM 3671 N PRO B 449 11.381 -54.404 0.449 1.00 12.40 N ANISOU 3671 N PRO B 449 2201 1524 989 -252 499 5 N ATOM 3672 CA PRO B 449 10.521 -54.479 -0.729 1.00 12.68 C ANISOU 3672 CA PRO B 449 1674 1680 1462 -255 276 35 C ATOM 3673 C PRO B 449 11.308 -54.752 -2.031 1.00 10.04 C ANISOU 3673 C PRO B 449 1442 1386 986 -16 270 -136 C ATOM 3674 O PRO B 449 10.716 -55.102 -3.045 1.00 11.05 O ANISOU 3674 O PRO B 449 1416 1571 1211 71 214 -296 O ATOM 3675 CB PRO B 449 9.814 -53.107 -0.754 1.00 16.66 C ANISOU 3675 CB PRO B 449 2271 2245 1814 -466 250 -171 C ATOM 3676 CG PRO B 449 10.817 -52.196 -0.030 1.00 16.24 C ANISOU 3676 CG PRO B 449 2564 1814 1793 -591 477 -122 C ATOM 3677 CD PRO B 449 11.358 -53.038 1.062 1.00 14.53 C ANISOU 3677 CD PRO B 449 2616 1620 1287 -297 614 136 C ATOM 3678 HA PRO B 449 9.849 -55.182 -0.609 1.00 15.23 H ATOM 3679 HB2 PRO B 449 9.678 -52.820 -1.671 1.00 20.01 H ATOM 3680 HB3 PRO B 449 8.974 -53.157 -0.273 1.00 20.01 H ATOM 3681 HG2 PRO B 449 11.520 -51.928 -0.642 1.00 19.50 H ATOM 3682 HG3 PRO B 449 10.357 -51.419 0.328 1.00 19.50 H ATOM 3683 HD2 PRO B 449 12.256 -52.756 1.296 1.00 17.46 H ATOM 3684 HD3 PRO B 449 10.766 -53.020 1.830 1.00 17.46 H ATOM 3685 N TYR B 450 12.600 -54.570 -1.998 1.00 9.20 N ANISOU 3685 N TYR B 450 1366 1211 918 106 332 172 N ATOM 3686 CA TYR B 450 13.454 -54.910 -3.123 1.00 8.81 C ANISOU 3686 CA TYR B 450 1430 1057 863 93 306 94 C ATOM 3687 C TYR B 450 13.728 -56.409 -3.181 1.00 9.19 C ANISOU 3687 C TYR B 450 1317 1187 989 49 227 40 C ATOM 3688 O TYR B 450 14.460 -56.847 -4.091 1.00 9.93 O ANISOU 3688 O TYR B 450 1561 1141 1070 7 338 193 O ATOM 3689 CB TYR B 450 14.769 -54.138 -2.980 1.00 9.91 C ANISOU 3689 CB TYR B 450 1458 1309 998 211 341 227 C ATOM 3690 CG TYR B 450 14.640 -52.691 -3.303 1.00 10.54 C ANISOU 3690 CG TYR B 450 1631 1042 1334 304 318 327 C ATOM 3691 CD1 TYR B 450 14.793 -52.217 -4.603 1.00 12.50 C ANISOU 3691 CD1 TYR B 450 2187 1239 1324 412 467 83 C ATOM 3692 CD2 TYR B 450 14.368 -51.759 -2.328 1.00 11.57 C ANISOU 3692 CD2 TYR B 450 1653 1049 1695 339 189 187 C ATOM 3693 CE1 TYR B 450 14.693 -50.901 -4.898 1.00 13.77 C ANISOU 3693 CE1 TYR B 450 2293 1527 1411 413 428 78 C ATOM 3694 CE2 TYR B 450 14.246 -50.434 -2.592 1.00 12.98 C ANISOU 3694 CE2 TYR B 450 2127 1347 1459 492 291 460 C ATOM 3695 CZ TYR B 450 14.463 -50.000 -3.908 1.00 14.81 C ANISOU 3695 CZ TYR B 450 2712 1227 1688 494 357 104 C ATOM 3696 OH TYR B 450 14.369 -48.673 -4.266 1.00 19.50 O ANISOU 3696 OH TYR B 450 3670 1268 2470 460 372 -92 O ATOM 3697 H TYR B 450 13.025 -54.245 -1.325 1.00 11.05 H ATOM 3698 HA TYR B 450 13.021 -54.638 -3.959 1.00 10.59 H ATOM 3699 HB2 TYR B 450 15.079 -54.213 -2.063 1.00 11.91 H ATOM 3700 HB3 TYR B 450 15.425 -54.522 -3.583 1.00 11.91 H ATOM 3701 HD1 TYR B 450 14.988 -52.820 -5.284 1.00 15.01 H ATOM 3702 HD2 TYR B 450 14.258 -52.050 -1.451 1.00 13.90 H ATOM 3703 HE1 TYR B 450 14.823 -50.609 -5.771 1.00 16.54 H ATOM 3704 HE2 TYR B 450 14.086 -49.824 -1.908 1.00 15.59 H ATOM 3705 HH TYR B 450 14.947 -48.237 -3.881 1.00 23.41 H ATOM 3706 N SER B 451 13.175 -57.183 -2.260 1.00 9.78 N ANISOU 3706 N SER B 451 1478 1045 1192 68 367 47 N ATOM 3707 CA SER B 451 13.434 -58.619 -2.172 1.00 10.50 C ANISOU 3707 CA SER B 451 1458 1158 1374 66 295 -46 C ATOM 3708 C SER B 451 12.155 -59.410 -2.115 1.00 9.83 C ANISOU 3708 C SER B 451 1555 1139 1039 -143 243 70 C ATOM 3709 O SER B 451 11.088 -58.858 -1.868 1.00 11.54 O ANISOU 3709 O SER B 451 1738 1223 1423 45 387 -50 O ATOM 3710 CB SER B 451 14.229 -58.892 -0.917 1.00 11.43 C ANISOU 3710 CB SER B 451 1647 1299 1397 -29 167 -100 C ATOM 3711 OG SER B 451 13.389 -58.995 0.224 1.00 13.20 O ANISOU 3711 OG SER B 451 1901 1777 1339 -47 84 -123 O ATOM 3712 H SER B 451 12.632 -56.897 -1.657 1.00 11.75 H ATOM 3713 HA SER B 451 13.955 -58.912 -2.949 1.00 12.62 H ATOM 3714 HB2 SER B 451 14.712 -59.725 -1.027 1.00 13.73 H ATOM 3715 HB3 SER B 451 14.856 -58.163 -0.779 1.00 13.73 H ATOM 3716 HG SER B 451 12.606 -58.889 0.006 1.00 15.86 H ATOM 3717 N ASP B 452 12.284 -60.731 -2.229 1.00 9.63 N ANISOU 3717 N ASP B 452 1561 1075 1023 46 385 -66 N ATOM 3718 CA ASP B 452 11.217 -61.636 -1.889 1.00 10.77 C ANISOU 3718 CA ASP B 452 1726 1336 1029 124 354 -74 C ATOM 3719 C ASP B 452 11.628 -62.524 -0.719 1.00 12.07 C ANISOU 3719 C ASP B 452 2225 1464 898 304 150 23 C ATOM 3720 O ASP B 452 11.109 -63.636 -0.578 1.00 14.77 O ANISOU 3720 O ASP B 452 2754 1439 1418 508 5 -266 O ATOM 3721 CB ASP B 452 10.736 -62.486 -3.049 1.00 11.22 C ANISOU 3721 CB ASP B 452 1701 1530 1032 322 136 98 C ATOM 3722 CG ASP B 452 9.362 -63.162 -2.800 1.00 15.09 C ANISOU 3722 CG ASP B 452 2628 1779 1325 344 288 198 C ATOM 3723 OD1 ASP B 452 8.481 -62.486 -2.240 1.00 17.61 O ANISOU 3723 OD1 ASP B 452 2537 1990 2163 486 582 -33 O ATOM 3724 OD2 ASP B 452 9.185 -64.338 -3.194 1.00 17.87 O ANISOU 3724 OD2 ASP B 452 3283 2144 1365 984 224 -2 O ATOM 3725 H ASP B 452 12.997 -61.125 -2.506 1.00 11.57 H ATOM 3726 HA ASP B 452 10.452 -61.102 -1.590 1.00 12.94 H ATOM 3727 HB2 ASP B 452 10.651 -61.922 -3.835 1.00 13.48 H ATOM 3728 HB3 ASP B 452 11.386 -63.187 -3.215 1.00 13.48 H ATOM 3729 N AGLU B 453 12.521 -62.080 0.131 0.56 13.50 N ANISOU 3729 N AGLU B 453 2520 1648 964 615 99 -238 N ATOM 3730 N BGLU B 453 12.372 -61.925 0.190 0.44 12.46 N ANISOU 3730 N BGLU B 453 2293 1734 705 455 -90 -111 N ATOM 3731 CA AGLU B 453 12.862 -62.919 1.259 0.56 13.69 C ANISOU 3731 CA AGLU B 453 2337 1904 960 799 148 -220 C ATOM 3732 CA BGLU B 453 12.733 -62.582 1.425 0.44 15.28 C ANISOU 3732 CA BGLU B 453 2351 1960 1496 334 -246 42 C ATOM 3733 C AGLU B 453 11.645 -62.916 2.210 0.56 14.52 C ANISOU 3733 C AGLU B 453 2696 1971 848 636 208 -123 C ATOM 3734 C BGLU B 453 11.490 -62.883 2.225 0.44 15.48 C ANISOU 3734 C BGLU B 453 2742 2024 1117 635 11 42 C ATOM 3735 O AGLU B 453 10.826 -62.026 2.221 0.56 16.48 O ANISOU 3735 O AGLU B 453 2839 2149 1274 296 765 -71 O ATOM 3736 O BGLU B 453 10.508 -62.150 2.171 0.44 16.22 O ANISOU 3736 O BGLU B 453 2975 2183 1005 1061 208 374 O ATOM 3737 CB AGLU B 453 14.165 -62.395 1.930 0.56 14.81 C ANISOU 3737 CB AGLU B 453 2245 1830 1553 93 95 474 C ATOM 3738 CB BGLU B 453 13.687 -61.709 2.285 0.44 13.07 C ANISOU 3738 CB BGLU B 453 2163 1681 1123 -27 -330 -67 C ATOM 3739 CG AGLU B 453 15.400 -62.660 1.126 0.56 14.62 C ANISOU 3739 CG AGLU B 453 2284 1769 1500 141 506 367 C ATOM 3740 CG BGLU B 453 13.076 -60.469 2.978 0.44 14.13 C ANISOU 3740 CG BGLU B 453 2068 1709 1593 43 -175 -35 C ATOM 3741 CD AGLU B 453 15.705 -64.136 0.981 0.56 14.33 C ANISOU 3741 CD AGLU B 453 2233 1809 1403 -97 677 -110 C ATOM 3742 CD BGLU B 453 14.063 -59.720 3.863 0.44 14.49 C ANISOU 3742 CD BGLU B 453 1997 1818 1692 96 -94 -881 C ATOM 3743 OE1AGLU B 453 15.956 -64.675 2.101 0.56 13.67 O ANISOU 3743 OE1AGLU B 453 2629 1626 938 -193 250 -95 O ATOM 3744 OE1BGLU B 453 14.991 -60.386 4.393 0.44 15.07 O ANISOU 3744 OE1BGLU B 453 2144 1878 1703 -113 -42 -87 O ATOM 3745 OE2AGLU B 453 15.545 -64.681 -0.197 0.56 10.59 O ANISOU 3745 OE2AGLU B 453 2233 1175 616 -56 716 -135 O ATOM 3746 OE2BGLU B 453 13.880 -58.488 3.974 0.44 11.60 O ANISOU 3746 OE2BGLU B 453 1567 1056 1787 -166 184 -488 O ATOM 3747 H AGLU B 453 12.932 -61.325 0.087 0.56 16.22 H ATOM 3748 H BGLU B 453 12.683 -61.127 0.113 0.44 14.96 H ATOM 3749 HA AGLU B 453 13.017 -63.837 0.952 0.56 16.44 H ATOM 3750 HA BGLU B 453 13.184 -63.429 1.224 0.44 18.36 H ATOM 3751 HB2AGLU B 453 14.090 -61.436 2.053 0.56 17.79 H ATOM 3752 HB2BGLU B 453 14.062 -62.270 2.982 0.44 15.70 H ATOM 3753 HB3AGLU B 453 14.271 -62.830 2.791 0.56 17.79 H ATOM 3754 HB3BGLU B 453 14.402 -61.392 1.712 0.44 15.70 H ATOM 3755 HG2AGLU B 453 15.284 -62.288 0.238 0.56 17.55 H ATOM 3756 HG2BGLU B 453 12.759 -59.852 2.299 0.44 16.97 H ATOM 3757 HG3AGLU B 453 16.157 -62.240 1.564 0.56 17.55 H ATOM 3758 HG3BGLU B 453 12.334 -60.754 3.535 0.44 16.97 H ATOM 3759 N ILE B 454 11.509 -63.953 3.007 1.00 14.98 N ANISOU 3759 N ILE B 454 2685 2046 963 594 300 -94 N ATOM 3760 CA ILE B 454 10.347 -64.168 3.825 1.00 16.75 C ANISOU 3760 CA ILE B 454 2989 2173 1203 1016 392 232 C ATOM 3761 C ILE B 454 10.240 -63.034 4.837 1.00 15.10 C ANISOU 3761 C ILE B 454 3001 1849 889 736 -14 171 C ATOM 3762 O ILE B 454 11.232 -62.537 5.380 1.00 15.83 O ANISOU 3762 O ILE B 454 2812 2182 1023 746 244 218 O ATOM 3763 CB ILE B 454 10.432 -65.507 4.605 1.00 18.02 C ANISOU 3763 CB ILE B 454 3415 1902 1530 1115 669 150 C ATOM 3764 CG1 ILE B 454 9.168 -65.745 5.434 1.00 22.68 C ANISOU 3764 CG1 ILE B 454 3830 2628 2161 1292 607 -151 C ATOM 3765 CG2 ILE B 454 11.628 -65.437 5.565 1.00 23.56 C ANISOU 3765 CG2 ILE B 454 3538 2755 2660 529 499 -281 C ATOM 3766 CD1 ILE B 454 7.908 -65.877 4.594 1.00 38.37 C ANISOU 3766 CD1 ILE B 454 4843 4622 5115 611 166 -195 C ATOM 3767 H AILE B 454 12.102 -64.570 3.092 0.56 18.00 H ATOM 3768 H BILE B 454 12.141 -64.532 3.077 0.44 18.00 H ATOM 3769 HA ILE B 454 9.541 -64.174 3.267 1.00 20.12 H ATOM 3770 HB ILE B 454 10.556 -66.239 3.983 1.00 21.64 H ATOM 3771 HG12 ILE B 454 9.275 -66.564 5.941 1.00 27.24 H ATOM 3772 HG13 ILE B 454 9.044 -64.996 6.039 1.00 27.24 H ATOM 3773 HG21 ILE B 454 11.686 -66.261 6.051 1.00 28.29 H ATOM 3774 HG22 ILE B 454 12.429 -65.299 5.054 1.00 28.29 H ATOM 3775 HG23 ILE B 454 11.497 -64.706 6.173 1.00 28.29 H ATOM 3776 HD11 ILE B 454 7.159 -66.023 5.176 1.00 46.06 H ATOM 3777 HD12 ILE B 454 7.781 -65.067 4.093 1.00 46.06 H ATOM 3778 HD13 ILE B 454 8.009 -66.621 3.995 1.00 46.06 H ATOM 3779 N GLU B 455 9.026 -62.607 5.096 1.00 14.96 N ANISOU 3779 N GLU B 455 2673 1974 1036 406 208 -93 N ATOM 3780 CA GLU B 455 8.771 -61.591 6.092 1.00 14.11 C ANISOU 3780 CA GLU B 455 2269 1918 1172 123 -17 -64 C ATOM 3781 C GLU B 455 9.246 -62.042 7.456 1.00 12.52 C ANISOU 3781 C GLU B 455 2138 1510 1110 206 178 37 C ATOM 3782 O GLU B 455 9.227 -63.232 7.780 1.00 14.77 O ANISOU 3782 O GLU B 455 2806 1625 1182 330 168 64 O ATOM 3783 CB GLU B 455 7.267 -61.345 6.153 1.00 18.87 C ANISOU 3783 CB GLU B 455 2736 2649 1786 -633 -382 234 C ATOM 3784 CG GLU B 455 6.649 -60.645 4.986 1.00 32.23 C ANISOU 3784 CG GLU B 455 3880 4005 4361 -178 -347 -78 C ATOM 3785 CD GLU B 455 5.130 -60.486 5.133 1.00 34.69 C ANISOU 3785 CD GLU B 455 4402 4484 4296 69 -3 -169 C ATOM 3786 OE1 GLU B 455 4.462 -61.370 5.750 1.00 41.49 O ANISOU 3786 OE1 GLU B 455 5463 5058 5244 206 430 -411 O ATOM 3787 OE2 GLU B 455 4.610 -59.477 4.578 1.00 40.63 O ANISOU 3787 OE2 GLU B 455 4758 5056 5624 -99 74 240 O ATOM 3788 H GLU B 455 8.318 -62.894 4.701 1.00 17.96 H ATOM 3789 HA GLU B 455 9.225 -60.755 5.850 1.00 16.94 H ATOM 3790 HB2 GLU B 455 6.824 -62.204 6.238 1.00 22.66 H ATOM 3791 HB3 GLU B 455 7.079 -60.810 6.940 1.00 22.66 H ATOM 3792 HG2 GLU B 455 7.038 -59.761 4.906 1.00 38.69 H ATOM 3793 HG3 GLU B 455 6.822 -61.159 4.181 1.00 38.69 H ATOM 3794 N TYR B 456 9.585 -61.063 8.248 1.00 11.66 N ANISOU 3794 N TYR B 456 2069 1393 967 114 229 -17 N ATOM 3795 CA TYR B 456 9.812 -61.276 9.678 1.00 10.00 C ANISOU 3795 CA TYR B 456 1584 1352 863 39 98 -53 C ATOM 3796 C TYR B 456 8.905 -60.312 10.447 1.00 9.95 C ANISOU 3796 C TYR B 456 1350 1340 1089 99 168 -100 C ATOM 3797 O TYR B 456 8.224 -59.458 9.875 1.00 12.28 O ANISOU 3797 O TYR B 456 1840 1740 1087 -156 254 -308 O ATOM 3798 CB TYR B 456 11.289 -61.146 10.037 1.00 11.91 C ANISOU 3798 CB TYR B 456 1807 1584 1134 -200 308 -67 C ATOM 3799 CG TYR B 456 11.940 -59.880 9.614 1.00 13.12 C ANISOU 3799 CG TYR B 456 1584 1918 1481 9 447 27 C ATOM 3800 CD1 TYR B 456 12.732 -59.840 8.464 1.00 17.81 C ANISOU 3800 CD1 TYR B 456 2302 2468 1995 -117 1109 -256 C ATOM 3801 CD2 TYR B 456 11.788 -58.710 10.303 1.00 15.24 C ANISOU 3801 CD2 TYR B 456 1977 2068 1744 313 356 -111 C ATOM 3802 CE1 TYR B 456 13.354 -58.696 8.103 1.00 21.57 C ANISOU 3802 CE1 TYR B 456 2581 3084 2532 552 1021 -701 C ATOM 3803 CE2 TYR B 456 12.454 -57.586 9.945 1.00 18.06 C ANISOU 3803 CE2 TYR B 456 2206 2660 1997 379 220 -337 C ATOM 3804 CZ TYR B 456 13.240 -57.544 8.834 1.00 20.99 C ANISOU 3804 CZ TYR B 456 2085 2997 2892 1087 -217 -549 C ATOM 3805 OH TYR B 456 13.882 -56.367 8.477 1.00 28.12 O ANISOU 3805 OH TYR B 456 3401 3743 3543 1662 -530 -1685 O ATOM 3806 H TYR B 456 9.696 -60.251 7.994 1.00 14.00 H ATOM 3807 HA TYR B 456 9.534 -62.188 9.906 1.00 12.01 H ATOM 3808 HB2 TYR B 456 11.377 -61.212 11.000 1.00 14.30 H ATOM 3809 HB3 TYR B 456 11.771 -61.876 9.617 1.00 14.30 H ATOM 3810 HD1 TYR B 456 12.856 -60.613 7.962 1.00 21.38 H ATOM 3811 HD2 TYR B 456 11.290 -58.710 11.089 1.00 18.30 H ATOM 3812 HE1 TYR B 456 13.896 -58.697 7.348 1.00 25.90 H ATOM 3813 HE2 TYR B 456 12.342 -56.812 10.450 1.00 21.69 H ATOM 3814 HH TYR B 456 13.633 -56.127 7.733 1.00 33.76 H ATOM 3815 N ILE B 457 8.860 -60.498 11.759 1.00 9.52 N ANISOU 3815 N ILE B 457 1488 1312 816 92 160 9 N ATOM 3816 CA ILE B 457 7.940 -59.797 12.630 1.00 9.51 C ANISOU 3816 CA ILE B 457 1391 1250 973 95 53 22 C ATOM 3817 C ILE B 457 8.770 -58.922 13.571 1.00 8.79 C ANISOU 3817 C ILE B 457 1266 1255 819 45 132 66 C ATOM 3818 O ILE B 457 9.701 -59.363 14.217 1.00 11.17 O ANISOU 3818 O ILE B 457 1591 1363 1291 -88 -205 199 O ATOM 3819 CB ILE B 457 7.067 -60.757 13.417 1.00 10.36 C ANISOU 3819 CB ILE B 457 1480 1410 1046 302 265 -68 C ATOM 3820 CG1 ILE B 457 6.232 -61.590 12.438 1.00 12.39 C ANISOU 3820 CG1 ILE B 457 1385 1653 1671 259 168 -94 C ATOM 3821 CG2 ILE B 457 6.140 -60.056 14.392 1.00 12.27 C ANISOU 3821 CG2 ILE B 457 1675 1620 1369 156 304 -208 C ATOM 3822 CD1 ILE B 457 5.562 -62.828 13.047 1.00 15.45 C ANISOU 3822 CD1 ILE B 457 2011 1720 2140 391 327 -34 C ATOM 3823 H ILE B 457 9.372 -61.047 12.178 1.00 11.44 H ATOM 3824 HA ILE B 457 7.360 -59.215 12.095 1.00 11.43 H ATOM 3825 HB ILE B 457 7.643 -61.357 13.916 1.00 12.45 H ATOM 3826 HG12 ILE B 457 5.530 -61.026 12.075 1.00 14.89 H ATOM 3827 HG13 ILE B 457 6.809 -61.892 11.720 1.00 14.89 H ATOM 3828 HG21 ILE B 457 5.618 -60.717 14.855 1.00 14.74 H ATOM 3829 HG22 ILE B 457 6.667 -59.556 15.019 1.00 14.74 H ATOM 3830 HG23 ILE B 457 5.562 -59.465 13.904 1.00 14.74 H ATOM 3831 HD11 ILE B 457 5.064 -63.282 12.363 1.00 18.56 H ATOM 3832 HD12 ILE B 457 6.241 -63.410 13.399 1.00 18.56 H ATOM 3833 HD13 ILE B 457 4.972 -62.550 13.752 1.00 18.56 H ATOM 3834 N AILE B 458 8.425 -57.638 13.631 0.50 9.12 N ANISOU 3834 N AILE B 458 1321 1217 929 -36 157 25 N ATOM 3835 N BILE B 458 8.370 -57.660 13.638 0.50 9.17 N ANISOU 3835 N BILE B 458 1386 1204 895 29 167 -22 N ATOM 3836 CA AILE B 458 9.051 -56.702 14.582 0.50 8.79 C ANISOU 3836 CA AILE B 458 1155 1296 889 -36 159 80 C ATOM 3837 CA BILE B 458 8.972 -56.681 14.537 0.50 9.13 C ANISOU 3837 CA BILE B 458 1159 1244 1064 34 214 47 C ATOM 3838 C AILE B 458 8.053 -56.365 15.679 0.50 9.86 C ANISOU 3838 C AILE B 458 1096 1311 1339 35 213 -299 C ATOM 3839 C BILE B 458 7.986 -56.506 15.675 0.50 8.67 C ANISOU 3839 C BILE B 458 1151 1233 910 118 -4 567 C ATOM 3840 O AILE B 458 6.947 -55.880 15.417 0.50 10.29 O ANISOU 3840 O AILE B 458 1054 1579 1277 66 380 124 O ATOM 3841 O BILE B 458 6.787 -56.331 15.449 0.50 9.03 O ANISOU 3841 O BILE B 458 1015 1314 1103 270 46 -54 O ATOM 3842 CB AILE B 458 9.515 -55.402 13.912 0.50 9.83 C ANISOU 3842 CB AILE B 458 1267 1419 1048 -59 77 -19 C ATOM 3843 CB BILE B 458 9.207 -55.368 13.793 0.50 10.91 C ANISOU 3843 CB BILE B 458 1475 1241 1429 190 253 10 C ATOM 3844 CG1AILE B 458 10.529 -55.654 12.805 0.50 11.57 C ANISOU 3844 CG1AILE B 458 1581 1519 1297 -79 -217 -38 C ATOM 3845 CG1BILE B 458 10.179 -55.581 12.663 0.50 10.70 C ANISOU 3845 CG1BILE B 458 1605 1252 1210 275 495 -57 C ATOM 3846 CG2AILE B 458 10.093 -54.410 14.953 0.50 12.36 C ANISOU 3846 CG2AILE B 458 1401 1499 1796 121 107 -143 C ATOM 3847 CG2BILE B 458 9.698 -54.245 14.735 0.50 12.44 C ANISOU 3847 CG2BILE B 458 1611 1228 1890 -105 70 443 C ATOM 3848 CD1AILE B 458 10.567 -54.528 11.771 0.50 14.43 C ANISOU 3848 CD1AILE B 458 1521 1787 2176 117 1 -236 C ATOM 3849 CD1BILE B 458 11.579 -56.042 13.151 0.50 13.00 C ANISOU 3849 CD1BILE B 458 1772 1420 1746 454 448 23 C ATOM 3850 H AILE B 458 7.828 -57.274 13.130 0.50 10.96 H ATOM 3851 H BILE B 458 7.733 -57.337 13.159 0.50 11.02 H ATOM 3852 HA AILE B 458 9.829 -57.132 14.995 0.50 10.56 H ATOM 3853 HA BILE B 458 9.823 -57.015 14.890 0.50 10.97 H ATOM 3854 HB AILE B 458 8.737 -54.986 13.509 0.50 11.81 H ATOM 3855 HB BILE B 458 8.362 -55.087 13.410 0.50 13.10 H ATOM 3856 HG12AILE B 458 11.413 -55.731 13.198 0.50 13.90 H ATOM 3857 HG12BILE B 458 9.828 -56.264 12.070 0.50 12.86 H ATOM 3858 HG13AILE B 458 10.297 -56.477 12.346 0.50 13.90 H ATOM 3859 HG13BILE B 458 10.290 -54.748 12.179 0.50 12.86 H ATOM 3860 HG21AILE B 458 10.373 -53.611 14.501 0.50 14.85 H ATOM 3861 HG21BILE B 458 9.831 -53.444 14.223 0.50 14.95 H ATOM 3862 HG22AILE B 458 9.412 -54.202 15.597 0.50 14.85 H ATOM 3863 HG22BILE B 458 9.035 -54.096 15.413 0.50 14.95 H ATOM 3864 HG23AILE B 458 10.843 -54.821 15.390 0.50 14.85 H ATOM 3865 HG23BILE B 458 10.525 -54.517 15.139 0.50 14.95 H ATOM 3866 HD11AILE B 458 11.221 -54.742 11.101 0.50 17.34 H ATOM 3867 HD11BILE B 458 12.152 -56.162 12.390 0.50 15.61 H ATOM 3868 HD12AILE B 458 9.700 -54.447 11.367 0.50 17.34 H ATOM 3869 HD12BILE B 458 11.943 -55.371 13.733 0.50 15.61 H ATOM 3870 HD13AILE B 458 10.804 -53.710 12.211 0.50 17.34 H ATOM 3871 HD13BILE B 458 11.487 -56.873 13.625 0.50 15.61 H ATOM 3872 N CYS B 459 8.488 -56.587 16.912 1.00 10.21 N ANISOU 3872 N CYS B 459 1217 1597 1064 -92 38 237 N ATOM 3873 CA CYS B 459 7.675 -56.418 18.091 1.00 10.16 C ANISOU 3873 CA CYS B 459 1276 1556 1027 -194 68 327 C ATOM 3874 C CYS B 459 8.267 -55.303 18.983 1.00 10.40 C ANISOU 3874 C CYS B 459 1284 1654 1011 -147 88 191 C ATOM 3875 O CYS B 459 9.478 -55.213 19.200 1.00 11.85 O ANISOU 3875 O CYS B 459 1218 1902 1384 -177 -13 290 O ATOM 3876 CB CYS B 459 7.704 -57.753 18.938 1.00 12.59 C ANISOU 3876 CB CYS B 459 1571 1976 1238 62 217 191 C ATOM 3877 SG CYS B 459 6.869 -59.096 18.127 1.00 14.46 S ANISOU 3877 SG CYS B 459 2012 1913 1569 27 -7 296 S ATOM 3878 H ACYS B 459 9.288 -56.849 17.091 0.50 12.26 H ATOM 3879 H BCYS B 459 9.316 -56.743 17.085 0.50 12.26 H ATOM 3880 HA CYS B 459 6.751 -56.197 17.850 1.00 12.20 H ATOM 3881 HB2 CYS B 459 8.626 -58.017 19.082 1.00 15.12 H ATOM 3882 HB3 CYS B 459 7.266 -57.598 19.790 1.00 15.12 H ATOM 3883 HG CYS B 459 6.937 -60.184 18.904 1.00 17.37 H ATOM 3884 N THR B 460 7.357 -54.549 19.580 1.00 9.62 N ANISOU 3884 N THR B 460 1262 1372 1019 -24 320 127 N ATOM 3885 CA THR B 460 7.671 -53.715 20.695 1.00 9.80 C ANISOU 3885 CA THR B 460 1242 1145 1338 88 342 140 C ATOM 3886 C THR B 460 6.951 -54.277 21.915 1.00 8.87 C ANISOU 3886 C THR B 460 1199 1242 927 326 311 186 C ATOM 3887 O THR B 460 5.727 -54.437 21.842 1.00 10.83 O ANISOU 3887 O THR B 460 1136 1812 1167 423 201 -45 O ATOM 3888 CB THR B 460 7.236 -52.275 20.398 1.00 15.46 C ANISOU 3888 CB THR B 460 2269 1366 2239 347 945 0 C ATOM 3889 OG1 THR B 460 7.767 -51.816 19.160 1.00 18.98 O ANISOU 3889 OG1 THR B 460 2446 1953 2811 242 640 -333 O ATOM 3890 CG2 THR B 460 7.657 -51.428 21.569 1.00 15.31 C ANISOU 3890 CG2 THR B 460 2484 1580 1754 460 358 307 C ATOM 3891 H THR B 460 6.531 -54.512 19.342 1.00 11.55 H ATOM 3892 HA THR B 460 8.637 -53.727 20.861 1.00 11.78 H ATOM 3893 HB THR B 460 6.267 -52.247 20.349 1.00 18.57 H ATOM 3894 HG1 THR B 460 7.504 -52.294 18.548 1.00 22.79 H ATOM 3895 HG21 THR B 460 7.401 -50.514 21.421 1.00 18.39 H ATOM 3896 HG22 THR B 460 7.235 -51.745 22.371 1.00 18.39 H ATOM 3897 HG23 THR B 460 8.609 -51.471 21.679 1.00 18.39 H ATOM 3898 N ASN B 461 7.698 -54.559 22.982 1.00 8.88 N ANISOU 3898 N ASN B 461 1119 1242 1014 341 216 241 N ATOM 3899 CA ASN B 461 7.211 -55.340 24.143 1.00 9.10 C ANISOU 3899 CA ASN B 461 1265 1341 851 447 309 125 C ATOM 3900 C ASN B 461 7.271 -54.441 25.360 1.00 9.11 C ANISOU 3900 C ASN B 461 1208 1270 985 339 343 113 C ATOM 3901 O ASN B 461 8.363 -54.139 25.800 1.00 10.50 O ANISOU 3901 O ASN B 461 1355 1475 1160 307 295 418 O ATOM 3902 CB ASN B 461 8.133 -56.554 24.305 1.00 10.74 C ANISOU 3902 CB ASN B 461 1741 1363 979 290 183 144 C ATOM 3903 CG ASN B 461 8.260 -57.377 23.061 1.00 10.71 C ANISOU 3903 CG ASN B 461 1611 1295 1162 321 298 75 C ATOM 3904 OD1 ASN B 461 7.293 -57.993 22.596 1.00 12.71 O ANISOU 3904 OD1 ASN B 461 1620 1641 1566 408 338 497 O ATOM 3905 ND2 ASN B 461 9.426 -57.361 22.470 1.00 10.94 N ANISOU 3905 ND2 ASN B 461 1433 1410 1312 315 183 120 N ATOM 3906 H ASN B 461 8.515 -54.306 23.067 1.00 10.67 H ATOM 3907 HA ASN B 461 6.290 -55.639 23.998 1.00 10.94 H ATOM 3908 HB2 ASN B 461 9.020 -56.245 24.548 1.00 12.91 H ATOM 3909 HB3 ASN B 461 7.780 -57.127 25.004 1.00 12.91 H ATOM 3910 HD21 ASN B 461 9.568 -57.880 21.651 1.00 13.14 H ATOM 3911 HD22 ASN B 461 10.159 -56.830 22.846 1.00 13.14 H ATOM 3912 N THR B 462 6.098 -54.051 25.853 1.00 9.87 N ANISOU 3912 N THR B 462 1311 1258 1180 316 455 121 N ATOM 3913 CA THR B 462 6.047 -53.078 26.970 1.00 9.80 C ANISOU 3913 CA THR B 462 1598 1053 1074 227 436 194 C ATOM 3914 C THR B 462 5.442 -53.734 28.209 1.00 10.09 C ANISOU 3914 C THR B 462 1625 1234 975 246 574 158 C ATOM 3915 O THR B 462 4.391 -54.374 28.073 1.00 10.70 O ANISOU 3915 O THR B 462 1625 1318 1121 487 434 166 O ATOM 3916 CB THR B 462 5.165 -51.887 26.575 1.00 14.06 C ANISOU 3916 CB THR B 462 2282 1336 1722 249 1154 72 C ATOM 3917 OG1 THR B 462 5.697 -51.297 25.380 1.00 16.63 O ANISOU 3917 OG1 THR B 462 2183 1605 2530 95 1125 -398 O ATOM 3918 CG2 THR B 462 5.194 -50.833 27.694 1.00 15.86 C ANISOU 3918 CG2 THR B 462 2623 1282 2120 167 672 -20 C ATOM 3919 H THR B 462 5.331 -54.322 25.574 1.00 11.85 H ATOM 3920 HA THR B 462 6.948 -52.756 27.182 1.00 11.78 H ATOM 3921 HB THR B 462 4.251 -52.177 26.430 1.00 16.88 H ATOM 3922 HG1 THR B 462 5.703 -51.850 24.774 1.00 19.97 H ATOM 3923 HG21 THR B 462 4.644 -50.085 27.453 1.00 19.04 H ATOM 3924 HG22 THR B 462 4.863 -51.213 28.511 1.00 19.04 H ATOM 3925 HG23 THR B 462 6.093 -50.527 27.833 1.00 19.04 H ATOM 3926 N ASN B 463 6.024 -53.550 29.391 1.00 10.39 N ANISOU 3926 N ASN B 463 1529 1432 985 452 325 242 N ATOM 3927 CA ASN B 463 5.385 -54.005 30.611 1.00 11.05 C ANISOU 3927 CA ASN B 463 1586 1371 1240 383 563 191 C ATOM 3928 C ASN B 463 4.241 -53.033 30.964 1.00 11.50 C ANISOU 3928 C ASN B 463 1734 1229 1408 366 553 447 C ATOM 3929 O ASN B 463 4.474 -51.836 31.082 1.00 16.71 O ANISOU 3929 O ASN B 463 2246 1419 2682 548 1349 868 O ATOM 3930 CB ASN B 463 6.490 -54.151 31.705 1.00 14.79 C ANISOU 3930 CB ASN B 463 2205 2145 1270 671 220 94 C ATOM 3931 CG ASN B 463 6.003 -54.805 33.114 1.00 14.59 C ANISOU 3931 CG ASN B 463 2093 1878 1573 683 32 552 C ATOM 3932 OD1 ASN B 463 6.665 -54.531 34.095 1.00 18.09 O ANISOU 3932 OD1 ASN B 463 2534 2643 1697 958 184 392 O ATOM 3933 ND2 ASN B 463 4.878 -55.566 33.228 1.00 11.52 N ANISOU 3933 ND2 ASN B 463 1716 1377 1284 193 86 369 N ATOM 3934 H ASN B 463 6.783 -53.163 29.509 1.00 12.48 H ATOM 3935 HA ASN B 463 4.994 -54.890 30.456 1.00 13.27 H ATOM 3936 HB2 ASN B 463 7.198 -54.712 31.353 1.00 17.76 H ATOM 3937 HB3 ASN B 463 6.844 -53.268 31.902 1.00 17.76 H ATOM 3938 HD21 ASN B 463 4.625 -55.940 34.099 1.00 13.84 H ATOM 3939 HD22 ASN B 463 4.322 -55.741 32.440 1.00 13.84 H ATOM 3940 N VAL B 464 3.037 -53.534 31.082 1.00 10.06 N ANISOU 3940 N VAL B 464 1465 1184 1172 161 417 46 N ATOM 3941 CA VAL B 464 1.834 -52.766 31.285 1.00 10.62 C ANISOU 3941 CA VAL B 464 1768 1199 1069 -59 482 -78 C ATOM 3942 C VAL B 464 1.070 -53.270 32.487 1.00 10.15 C ANISOU 3942 C VAL B 464 1808 998 1050 -94 415 144 C ATOM 3943 O VAL B 464 1.336 -54.347 33.021 1.00 10.08 O ANISOU 3943 O VAL B 464 1720 984 1127 -37 398 13 O ATOM 3944 CB VAL B 464 0.951 -52.740 30.033 1.00 11.63 C ANISOU 3944 CB VAL B 464 1872 1482 1065 -341 483 -310 C ATOM 3945 CG1 VAL B 464 1.688 -52.150 28.834 1.00 13.92 C ANISOU 3945 CG1 VAL B 464 2312 1502 1476 -112 488 -158 C ATOM 3946 CG2 VAL B 464 0.478 -54.144 29.734 1.00 11.56 C ANISOU 3946 CG2 VAL B 464 1534 1767 1092 52 202 -83 C ATOM 3947 H VAL B 464 2.882 -54.378 31.045 1.00 12.08 H ATOM 3948 HA VAL B 464 2.093 -51.840 31.474 1.00 12.76 H ATOM 3949 HB VAL B 464 0.163 -52.184 30.208 1.00 13.97 H ATOM 3950 HG11 VAL B 464 1.101 -52.151 28.074 1.00 16.72 H ATOM 3951 HG12 VAL B 464 1.952 -51.249 29.041 1.00 16.72 H ATOM 3952 HG13 VAL B 464 2.464 -52.683 28.650 1.00 16.72 H ATOM 3953 HG21 VAL B 464 -0.075 -54.128 28.949 1.00 13.89 H ATOM 3954 HG22 VAL B 464 1.243 -54.706 29.584 1.00 13.89 H ATOM 3955 HG23 VAL B 464 -0.025 -54.471 30.483 1.00 13.89 H ATOM 3956 N LYS B 465 0.096 -52.465 32.891 1.00 11.10 N ANISOU 3956 N LYS B 465 1840 1189 1187 -214 479 -128 N ATOM 3957 CA LYS B 465 -0.814 -52.875 33.942 1.00 11.44 C ANISOU 3957 CA LYS B 465 1693 1469 1184 -429 471 -10 C ATOM 3958 C LYS B 465 -2.019 -53.657 33.449 1.00 11.55 C ANISOU 3958 C LYS B 465 1429 1724 1235 -55 -2 -259 C ATOM 3959 O LYS B 465 -2.570 -53.352 32.415 1.00 16.07 O ANISOU 3959 O LYS B 465 2299 2372 1434 -95 -71 -446 O ATOM 3960 CB LYS B 465 -1.367 -51.654 34.707 1.00 15.71 C ANISOU 3960 CB LYS B 465 2259 1980 1730 -362 623 -341 C ATOM 3961 CG LYS B 465 -0.311 -50.879 35.468 1.00 17.18 C ANISOU 3961 CG LYS B 465 2332 1958 2236 -130 447 536 C ATOM 3962 CD LYS B 465 -0.727 -49.510 36.113 1.00 27.01 C ANISOU 3962 CD LYS B 465 3354 3296 3612 -337 227 673 C ATOM 3963 CE LYS B 465 -1.802 -49.546 37.023 1.00 30.03 C ANISOU 3963 CE LYS B 465 3896 3559 3953 -401 -283 141 C ATOM 3964 NZ LYS B 465 -1.995 -48.151 37.603 1.00 26.23 N ANISOU 3964 NZ LYS B 465 3640 2894 3433 -997 -211 1134 N ATOM 3965 H LYS B 465 -0.056 -51.681 32.572 1.00 13.33 H ATOM 3966 HA LYS B 465 -0.329 -53.438 34.581 1.00 13.74 H ATOM 3967 HB2 LYS B 465 -1.778 -51.047 34.071 1.00 18.87 H ATOM 3968 HB3 LYS B 465 -2.030 -51.958 35.346 1.00 18.87 H ATOM 3969 HG2 LYS B 465 0.012 -51.442 36.188 1.00 20.63 H ATOM 3970 HG3 LYS B 465 0.420 -50.693 34.859 1.00 20.63 H ATOM 3971 HD2 LYS B 465 0.039 -49.152 36.587 1.00 32.43 H ATOM 3972 HD3 LYS B 465 -0.975 -48.902 35.399 1.00 32.43 H ATOM 3973 HE2 LYS B 465 -2.614 -49.808 36.563 1.00 36.05 H ATOM 3974 HE3 LYS B 465 -1.600 -50.160 37.746 1.00 36.05 H ATOM 3975 HZ1 LYS B 465 -2.724 -48.154 38.227 1.00 31.50 H ATOM 3976 HZ2 LYS B 465 -1.197 -47.871 38.057 1.00 31.50 H ATOM 3977 HZ3 LYS B 465 -2.189 -47.527 36.899 1.00 31.50 H ATOM 3978 N ASN B 466 -2.446 -54.623 34.228 1.00 11.18 N ANISOU 3978 N ASN B 466 1400 1571 1279 -108 167 -64 N ATOM 3979 CA ASN B 466 -3.757 -55.246 34.040 1.00 12.42 C ANISOU 3979 CA ASN B 466 1299 1763 1659 -233 235 57 C ATOM 3980 C ASN B 466 -4.596 -54.747 35.206 1.00 16.45 C ANISOU 3980 C ASN B 466 2000 1817 2432 83 160 83 C ATOM 3981 O ASN B 466 -4.550 -55.320 36.292 1.00 17.78 O ANISOU 3981 O ASN B 466 2275 2196 2287 137 457 -51 O ATOM 3982 CB ASN B 466 -3.694 -56.752 34.021 1.00 13.33 C ANISOU 3982 CB ASN B 466 1590 1826 1650 -296 -95 251 C ATOM 3983 CG ASN B 466 -5.042 -57.368 33.678 1.00 15.35 C ANISOU 3983 CG ASN B 466 1620 2094 2118 -106 -745 363 C ATOM 3984 OD1 ASN B 466 -5.765 -56.819 32.853 1.00 19.03 O ANISOU 3984 OD1 ASN B 466 2111 2456 2662 34 -941 207 O ATOM 3985 ND2 ASN B 466 -5.358 -58.541 34.245 1.00 16.48 N ANISOU 3985 ND2 ASN B 466 1735 1964 2560 -225 -292 325 N ATOM 3986 H ASN B 466 -1.997 -54.947 34.885 1.00 13.44 H ATOM 3987 HA ASN B 466 -4.159 -54.934 33.202 1.00 14.92 H ATOM 3988 HB2 ASN B 466 -3.052 -57.036 33.351 1.00 16.02 H ATOM 3989 HB3 ASN B 466 -3.428 -57.072 34.897 1.00 16.02 H ATOM 3990 HD21 ASN B 466 -6.219 -58.965 34.045 1.00 19.79 H ATOM 3991 HD22 ASN B 466 -4.729 -58.973 34.858 1.00 19.79 H ATOM 3992 N ASER B 467 -5.363 -53.720 34.907 0.50 18.24 N ANISOU 3992 N ASER B 467 1828 2290 2812 -343 156 297 N ATOM 3993 N BSER B 467 -5.272 -53.614 35.035 0.50 18.09 N ANISOU 3993 N BSER B 467 1876 2224 2775 -436 328 450 N ATOM 3994 CA ASER B 467 -6.149 -53.011 35.891 0.50 18.84 C ANISOU 3994 CA ASER B 467 2187 2469 2500 -350 231 567 C ATOM 3995 CA BSER B 467 -6.053 -52.974 36.123 0.50 20.89 C ANISOU 3995 CA BSER B 467 2433 2513 2990 -72 220 451 C ATOM 3996 C ASER B 467 -7.182 -52.139 35.201 0.50 17.01 C ANISOU 3996 C ASER B 467 1698 2396 2371 -201 524 552 C ATOM 3997 C BSER B 467 -7.390 -52.507 35.597 0.50 22.38 C ANISOU 3997 C BSER B 467 2907 2653 2945 8 -39 -46 C ATOM 3998 O ASER B 467 -7.012 -51.638 34.064 0.50 18.95 O ANISOU 3998 O ASER B 467 1405 2690 3106 -468 -217 352 O ATOM 3999 O BSER B 467 -7.501 -52.198 34.411 0.50 23.03 O ANISOU 3999 O BSER B 467 2841 2690 3219 -293 371 352 O ATOM 4000 CB ASER B 467 -5.230 -52.167 36.772 0.50 19.33 C ANISOU 4000 CB ASER B 467 2128 2764 2452 -1003 807 832 C ATOM 4001 CB BSER B 467 -5.322 -51.772 36.755 0.50 21.39 C ANISOU 4001 CB BSER B 467 2651 2658 2819 240 -173 -704 C ATOM 4002 OG ASER B 467 -4.697 -51.125 35.974 0.50 25.84 O ANISOU 4002 OG ASER B 467 2879 3089 3849 -470 931 619 O ATOM 4003 OG BSER B 467 -4.025 -52.154 37.179 0.50 26.57 O ANISOU 4003 OG BSER B 467 3144 3227 3723 23 -84 -105 O ATOM 4004 H ASER B 467 -5.447 -53.403 34.112 0.50 21.90 H ATOM 4005 H BSER B 467 -5.301 -53.182 34.292 0.50 21.73 H ATOM 4006 HA ASER B 467 -6.619 -53.657 36.460 0.50 22.62 H ATOM 4007 HA BSER B 467 -6.218 -53.635 36.828 0.50 25.08 H ATOM 4008 HB2ASER B 467 -5.740 -51.788 37.505 0.50 23.21 H ATOM 4009 HB2BSER B 467 -5.245 -51.065 36.096 0.50 25.68 H ATOM 4010 HB3ASER B 467 -4.507 -52.719 37.110 0.50 23.21 H ATOM 4011 HB3BSER B 467 -5.828 -51.461 37.522 0.50 25.68 H ATOM 4012 HG ASER B 467 -4.198 -50.654 36.423 0.50 31.02 H ATOM 4013 HG BSER B 467 -3.639 -51.513 37.514 0.50 31.89 H TER 4014 SER B 467 HETATM 4015 O HOH A 9 21.451 -57.628 -0.911 1.00 15.39 O HETATM 4016 O HOH A 10 10.430 -37.504 9.770 1.00 18.58 O HETATM 4017 O HOH A 12 22.006 -30.858 4.102 1.00 15.16 O HETATM 4018 O HOH A 14 15.404 -31.585 8.878 1.00 13.88 O HETATM 4019 O HOH A 15 13.504 -41.028 9.510 1.00 16.02 O HETATM 4020 O HOH A 19 7.817 -49.530 10.862 1.00 16.45 O HETATM 4021 O HOH A 21 20.044 -47.723 21.585 1.00 18.93 O HETATM 4022 O HOH A 26 20.611 -55.416 -2.445 1.00 19.13 O HETATM 4023 O HOH A 28 27.445 -52.092 12.394 1.00 20.52 O HETATM 4024 O HOH A 29 18.053 -47.458 23.757 1.00 18.95 O HETATM 4025 O HOH A 31 8.821 -39.720 10.488 1.00 19.15 O HETATM 4026 O HOH A 32 14.470 -43.063 11.197 0.99 19.12 O HETATM 4027 O HOH A 34 21.184 -30.577 6.575 1.00 21.09 O HETATM 4028 O HOH A 35 12.858 -38.709 23.664 1.00 21.02 O HETATM 4029 O HOH A 38 6.843 -29.552 4.958 1.00 25.86 O HETATM 4030 O HOH A 40 21.288 -50.868 -1.158 1.00 23.28 O HETATM 4031 O HOH A 41 29.438 -46.456 2.040 1.00 26.68 O HETATM 4032 O HOH A 43 27.750 -47.417 3.921 1.00 24.54 O HETATM 4033 O HOH A 45 17.117 -32.480 18.436 1.00 22.90 O HETATM 4034 O HOH A 47 30.523 -42.236 8.260 1.00 24.31 O HETATM 4035 O HOH A 51 8.471 -50.797 3.141 1.00 30.17 O HETATM 4036 O HOH A 54 25.192 -52.892 8.957 1.00 19.34 O HETATM 4037 O HOH A 56 23.506 -59.183 5.399 1.00 26.32 O HETATM 4038 O HOH A 57 13.053 -46.716 -3.123 1.00 25.37 O HETATM 4039 O HOH A 58 6.386 -36.249 2.023 0.97 26.85 O HETATM 4040 O HOH A 61 25.125 -53.671 -1.415 0.91 20.43 O HETATM 4041 O HOH A 69 10.917 -40.961 -3.264 1.00 32.35 O HETATM 4042 O HOH A 71 16.196 -44.208 25.282 1.00 29.85 O HETATM 4043 O HOH A 72 27.841 -49.946 17.275 1.00 29.25 O HETATM 4044 O HOH A 74 25.856 -51.169 -0.132 0.88 25.57 O HETATM 4045 O HOH A 75 21.791 -50.473 20.321 1.00 28.75 O HETATM 4046 O HOH A 76 3.060 -44.594 2.948 1.00 27.44 O HETATM 4047 O HOH A 77 25.835 -35.938 12.652 0.88 27.07 O HETATM 4048 O HOH A 79 23.925 -49.740 -1.493 0.92 27.17 O HETATM 4049 O HOH A 81 11.048 -29.575 10.030 1.00 29.79 O HETATM 4050 O HOH A 82 -0.659 -40.681 16.288 1.00 26.69 O HETATM 4051 O HOH A 84 31.385 -40.706 5.829 1.00 28.59 O HETATM 4052 O HOH A 85 25.805 -46.485 -4.099 1.00 27.86 O HETATM 4053 O HOH A 86 8.701 -43.221 8.002 0.93 22.97 O HETATM 4054 O HOH A 87 21.361 -32.907 7.919 0.84 21.80 O HETATM 4055 O HOH A 88 10.747 -41.787 9.343 1.00 23.73 O HETATM 4056 O HOH A 93 25.525 -47.911 2.860 1.00 27.21 O HETATM 4057 O HOH A 94 26.424 -58.767 3.896 1.00 32.65 O HETATM 4058 O HOH A 96 15.410 -39.398 23.278 0.98 25.61 O HETATM 4059 O HOH A 100 5.752 -33.002 11.147 0.90 27.74 O HETATM 4060 O HOH A 101 7.758 -30.493 0.742 1.00 39.78 O HETATM 4061 O HOH A 104 17.181 -55.348 4.340 0.88 21.72 O HETATM 4062 O HOH A 105 7.524 -40.770 8.200 0.78 23.41 O HETATM 4063 O HOH A 106 24.630 -32.257 -0.800 1.00 35.20 O HETATM 4064 O HOH A 107 23.476 -39.224 22.991 0.90 30.37 O HETATM 4065 O HOH A 111 26.226 -31.262 4.452 0.90 31.54 O HETATM 4066 O HOH A 113 4.390 -34.182 13.219 1.00 31.88 O HETATM 4067 O HOH A 116 22.466 -55.224 15.479 0.97 25.54 O HETATM 4068 O HOH A 117 22.233 -53.687 18.184 1.00 28.06 O HETATM 4069 O HOH A 121 1.872 -33.938 13.083 1.00 36.14 O HETATM 4070 O HOH A 122 20.441 -53.253 19.730 1.00 29.63 O HETATM 4071 O HOH A 125 5.433 -48.392 24.957 1.00 30.82 O HETATM 4072 O HOH A 126 9.586 -38.444 2.508 0.89 24.72 O HETATM 4073 O HOH A 127 7.308 -26.995 2.018 1.00 29.87 O HETATM 4074 O HOH A 128 22.457 -46.959 22.800 0.98 27.58 O HETATM 4075 O HOH A 133 22.474 -43.109 -5.682 1.00 37.47 O HETATM 4076 O HOH A 134 4.775 -34.744 16.595 1.00 43.31 O HETATM 4077 O HOH A 135 22.670 -35.132 -2.643 0.78 39.36 O HETATM 4078 O HOH A 139 24.616 -48.681 22.800 0.94 35.98 O HETATM 4079 O HOH A 141 17.239 -34.947 24.222 0.94 38.42 O HETATM 4080 O HOH A 142 12.696 -35.499 -0.329 0.93 30.27 O HETATM 4081 O HOH A 150 18.623 -47.313 26.522 0.93 31.08 O HETATM 4082 O HOH A 153 5.382 -28.401 10.838 1.00 32.57 O HETATM 4083 O HOH A 154 2.271 -30.883 12.256 0.95 36.22 O HETATM 4084 O HOH A 155 4.598 -29.082 6.413 0.93 27.78 O HETATM 4085 O HOH A 156 29.204 -32.011 8.722 1.00 35.80 O HETATM 4086 O HOH A 157 28.498 -31.917 6.037 0.94 29.95 O HETATM 4087 O HOH A 158 26.758 -54.301 10.729 1.00 31.54 O HETATM 4088 O HOH A 159 24.754 -59.246 8.142 1.00 32.89 O HETATM 4089 O HOH A 160 11.053 -45.786 -4.654 0.99 37.40 O HETATM 4090 O HOH A 167 2.149 -50.311 23.990 1.00 29.05 O HETATM 4091 O HOH A 168 -1.750 -49.457 9.848 1.00 32.03 O HETATM 4092 O HOH A 173 6.923 -39.721 22.635 0.98 34.38 O HETATM 4093 O HOH A 176 18.019 -32.767 21.079 1.00 31.94 O HETATM 4094 O HOH A 177 26.953 -53.123 6.845 1.00 31.84 O HETATM 4095 O HOH A 180 22.556 -46.325 -5.105 0.90 30.13 O HETATM 4096 O HOH A 182 4.107 -39.879 23.422 0.96 33.28 O HETATM 4097 O HOH A 183 7.734 -36.680 21.752 0.82 31.88 O HETATM 4098 O HOH A 184 26.316 -37.584 17.898 0.99 37.84 O HETATM 4099 O HOH A 186 6.351 -43.674 25.425 0.93 29.95 O HETATM 4100 O HOH A 187 24.272 -37.263 -1.838 1.00 38.85 O HETATM 4101 O HOH A 188 32.123 -49.967 12.146 1.00 45.81 O HETATM 4102 O HOH A 190 -5.593 -39.364 13.221 0.97 37.86 O HETATM 4103 O HOH A 191 8.551 -42.111 23.272 1.00 33.48 O HETATM 4104 O HOH A 194 23.524 -39.390 -0.916 1.00 38.72 O HETATM 4105 O HOH A 195 10.605 -35.935 23.713 0.95 35.19 O HETATM 4106 O HOH A 198 11.545 -40.279 25.507 0.98 31.42 O HETATM 4107 O HOH A 200 19.700 -51.027 -3.313 1.00 29.75 O HETATM 4108 O HOH A 201 15.725 -61.392 9.734 1.00 28.97 O HETATM 4109 O HOH A 202 31.341 -57.184 -3.754 0.97 29.76 O HETATM 4110 O HOH A 204 28.624 -42.639 21.990 0.91 30.94 O HETATM 4111 O HOH A 209 -7.667 -49.046 19.989 1.00 39.14 O HETATM 4112 O HOH A 210 11.446 -32.343 21.613 1.00 30.93 O HETATM 4113 O HOH A 211 11.538 -37.780 0.583 0.88 34.44 O HETATM 4114 O HOH A 212 7.528 -28.902 11.991 0.85 31.45 O HETATM 4115 O HOH A 214 -9.640 -49.661 23.062 1.00 33.23 O HETATM 4116 O HOH A 217 29.256 -53.844 -0.731 1.00 34.30 O HETATM 4117 O HOH A 220 25.964 -50.591 2.570 0.99 39.17 O HETATM 4118 O HOH A 221 24.028 -57.287 9.749 1.00 32.92 O HETATM 4119 O HOH A 222 -1.543 -44.277 27.869 1.00 43.65 O HETATM 4120 O HOH A 225 25.415 -54.973 14.432 0.94 38.82 O HETATM 4121 O HOH A 230 31.668 -52.911 -1.451 1.00 36.04 O HETATM 4122 O HOH A 231 0.264 -48.340 28.329 1.00 38.40 O HETATM 4123 O HOH A 232 16.982 -41.301 9.084 0.85 30.78 O HETATM 4124 O HOH A 233 19.880 -32.797 -4.992 0.91 33.98 O HETATM 4125 O HOH A 352 21.737 -36.221 22.930 0.92 37.53 O HETATM 4126 O HOH A 353 17.053 -59.243 8.845 1.00 35.38 O HETATM 4127 O HOH A 354 -4.556 -40.748 18.593 1.00 41.31 O HETATM 4128 O HOH A 355 28.319 -48.559 20.781 1.00 40.48 O HETATM 4129 O HOH A 356 13.050 -36.349 25.192 0.89 34.68 O HETATM 4130 O HOH A 357 31.412 -47.018 9.124 1.00 41.17 O HETATM 4131 O HOH A 358 31.196 -44.678 8.104 1.00 41.13 O HETATM 4132 O HOH A 359 30.180 -51.936 13.696 1.00 44.16 O HETATM 4133 O HOH A 360 -1.159 -46.212 7.132 0.93 34.72 O HETATM 4134 O HOH A 361 21.198 -32.126 19.392 1.00 30.30 O HETATM 4135 O HOH A 362 0.000 -48.065 14.049 1.00 24.93 O HETATM 4136 O AHOH A 363 18.474 -52.414 1.569 0.46 17.21 O HETATM 4137 O BHOH A 363 17.875 -52.021 0.675 0.54 17.27 O HETATM 4138 O AHOH A 364 0.235 -50.064 19.076 0.56 18.52 O HETATM 4139 O BHOH A 364 0.162 -49.533 17.646 0.44 24.54 O HETATM 4140 O HOH A 365 17.414 -63.354 11.163 1.00 39.13 O HETATM 4141 O HOH A 471 19.405 -48.095 -5.233 0.97 38.52 O HETATM 4142 O HOH B 1 -4.692 -68.537 24.786 1.00 13.29 O HETATM 4143 O HOH B 2 -6.667 -59.495 15.275 1.00 12.18 O HETATM 4144 O HOH B 3 12.350 -67.736 34.406 1.00 14.00 O HETATM 4145 O HOH B 4 2.579 -70.246 37.136 1.00 16.35 O HETATM 4146 O HOH B 5 10.437 -65.263 9.188 1.00 15.25 O HETATM 4147 O HOH B 6 13.787 -72.984 38.561 1.00 13.90 O HETATM 4148 O HOH B 7 10.192 -60.386 38.237 1.00 16.47 O HETATM 4149 O HOH B 8 6.985 -71.276 32.271 0.99 15.75 O HETATM 4150 O HOH B 11 -5.905 -66.008 28.324 1.00 15.56 O HETATM 4151 O HOH B 13 11.788 -71.002 28.954 1.00 17.12 O HETATM 4152 O HOH B 16 18.423 -53.204 29.999 0.98 16.84 O HETATM 4153 O HOH B 17 -5.303 -56.804 24.174 1.00 18.95 O HETATM 4154 O HOH B 18 -3.197 -71.264 25.742 1.00 18.33 O HETATM 4155 O HOH B 20 14.069 -62.678 11.589 1.00 20.50 O HETATM 4156 O HOH B 22 5.381 -67.294 39.132 1.00 18.84 O HETATM 4157 O HOH B 23 -4.633 -66.763 13.634 0.99 14.73 O HETATM 4158 O HOH B 24 1.588 -56.940 9.912 0.99 16.23 O HETATM 4159 O HOH B 25 13.042 -64.490 9.790 1.00 19.59 O HETATM 4160 O HOH B 27 -4.695 -55.253 13.341 1.00 22.15 O HETATM 4161 O HOH B 30 -3.781 -60.512 19.386 0.93 14.18 O HETATM 4162 O HOH B 33 20.648 -53.709 21.899 1.00 26.79 O HETATM 4163 O HOH B 36 15.629 -56.142 10.658 1.00 21.86 O HETATM 4164 O HOH B 37 11.180 -68.218 41.780 1.00 22.75 O HETATM 4165 O HOH B 39 -5.322 -60.069 21.595 1.00 18.76 O HETATM 4166 O HOH B 42 -4.659 -55.901 17.528 1.00 21.28 O HETATM 4167 O HOH B 44 3.176 -49.226 30.746 1.00 24.75 O HETATM 4168 O HOH B 46 19.510 -51.438 23.923 1.00 30.38 O HETATM 4169 O HOH B 48 13.644 -65.966 2.858 0.97 21.67 O HETATM 4170 O HOH B 49 6.301 -50.060 32.000 1.00 27.01 O HETATM 4171 O HOH B 50 17.258 -68.092 31.305 1.00 27.31 O HETATM 4172 O HOH B 52 5.234 -56.692 5.582 1.00 29.80 O HETATM 4173 O HOH B 53 12.910 -49.581 28.166 1.00 23.80 O HETATM 4174 O HOH B 55 0.207 -67.558 9.153 0.99 23.67 O HETATM 4175 O HOH B 59 -5.683 -57.316 20.261 0.84 23.59 O HETATM 4176 O HOH B 60 15.432 -49.542 29.603 1.00 26.88 O HETATM 4177 O HOH B 62 6.935 -54.481 4.988 1.00 29.38 O HETATM 4178 O HOH B 63 14.390 -73.837 23.190 1.00 21.84 O HETATM 4179 O HOH B 64 9.580 -60.933 44.223 1.00 25.65 O HETATM 4180 O HOH B 65 1.419 -58.715 7.266 0.99 22.92 O HETATM 4181 O HOH B 66 4.656 -53.349 8.066 1.00 22.93 O HETATM 4182 O HOH B 67 3.546 -66.165 11.313 0.99 25.18 O HETATM 4183 O HOH B 68 -0.560 -59.683 4.569 1.00 22.83 O HETATM 4184 O AHOH B 70 6.073 -71.058 29.336 0.60 30.12 O HETATM 4185 O BHOH B 70 4.564 -71.180 30.445 0.40 21.27 O HETATM 4186 O HOH B 73 21.111 -56.599 21.665 1.00 31.40 O HETATM 4187 O HOH B 78 6.544 -53.144 16.754 0.92 18.73 O HETATM 4188 O HOH B 80 2.327 -69.234 15.815 1.00 31.22 O HETATM 4189 O HOH B 83 -3.246 -55.039 23.581 1.00 29.42 O HETATM 4190 O HOH B 89 17.861 -66.639 2.099 1.00 23.70 O HETATM 4191 O HOH B 90 3.199 -68.659 13.389 0.98 31.97 O HETATM 4192 O HOH B 91 20.000 -58.460 12.433 0.92 24.66 O HETATM 4193 O HOH B 92 -6.022 -65.995 34.795 1.00 33.18 O HETATM 4194 O HOH B 95 8.103 -53.645 2.683 0.89 35.58 O HETATM 4195 O HOH B 97 17.625 -66.907 16.497 1.00 24.23 O HETATM 4196 O HOH B 98 20.244 -51.380 26.664 1.00 33.57 O HETATM 4197 O HOH B 99 4.826 -45.395 32.494 0.98 28.23 O HETATM 4198 O HOH B 103 -1.350 -72.766 16.611 1.00 28.95 O HETATM 4199 O HOH B 108 8.750 -57.388 -1.866 0.89 30.54 O HETATM 4200 O HOH B 109 -1.228 -50.359 12.234 0.99 27.36 O HETATM 4201 O HOH B 110 16.018 -66.601 38.662 1.00 30.45 O HETATM 4202 O HOH B 112 -6.924 -69.380 27.846 1.00 32.27 O HETATM 4203 O HOH B 114 15.451 -71.303 40.197 1.00 28.13 O HETATM 4204 O HOH B 115 21.983 -57.536 13.929 0.96 27.70 O HETATM 4205 O HOH B 118 16.847 -47.966 -5.752 1.00 28.08 O HETATM 4206 O AHOH B 119 15.719 -57.428 5.413 0.65 29.54 O HETATM 4207 O BHOH B 119 15.259 -56.005 6.309 0.35 33.69 O HETATM 4208 O HOH B 120 17.077 -59.592 6.110 1.00 29.59 O HETATM 4209 O HOH B 123 7.631 -59.808 -2.971 0.99 16.81 O HETATM 4210 O HOH B 124 9.600 -54.757 34.226 1.00 23.51 O HETATM 4211 O HOH B 129 9.237 -66.281 41.636 0.97 23.66 O HETATM 4212 O HOH B 130 6.949 -54.953 36.935 0.94 26.43 O HETATM 4213 O HOH B 131 -0.934 -73.852 27.230 1.00 28.81 O HETATM 4214 O HOH B 132 -1.337 -73.864 24.515 1.00 26.85 O HETATM 4215 O HOH B 136 20.594 -61.223 16.957 0.98 28.20 O HETATM 4216 O HOH B 137 9.824 -69.300 10.802 0.97 27.68 O HETATM 4217 O HOH B 138 21.169 -67.480 22.313 1.00 29.51 O HETATM 4218 O HOH B 140 -2.844 -51.903 30.182 1.00 32.39 O HETATM 4219 O HOH B 143 19.822 -62.614 33.278 0.90 24.34 O HETATM 4220 O HOH B 144 10.938 -67.930 8.467 0.99 27.71 O HETATM 4221 O HOH B 145 -0.066 -70.759 37.400 1.00 33.48 O HETATM 4222 O HOH B 146 3.880 -69.525 39.452 1.00 22.62 O HETATM 4223 O HOH B 147 14.280 -52.779 35.589 1.00 27.14 O HETATM 4224 O HOH B 148 20.281 -53.041 32.011 1.00 32.09 O HETATM 4225 O HOH B 149 16.282 -47.248 28.129 1.00 30.73 O HETATM 4226 O HOH B 151 14.176 -46.462 26.389 1.00 32.98 O HETATM 4227 O HOH B 152 2.915 -67.674 9.171 0.90 25.45 O HETATM 4228 O HOH B 161 -1.958 -60.667 2.861 1.00 37.11 O HETATM 4229 O HOH B 162 17.834 -50.468 29.745 1.00 27.72 O HETATM 4230 O HOH B 163 9.255 -49.452 19.484 1.00 28.17 O HETATM 4231 O HOH B 164 3.718 -52.386 23.036 1.00 23.36 O HETATM 4232 O HOH B 165 23.429 -61.700 25.923 1.00 23.72 O HETATM 4233 O HOH B 166 9.325 -72.486 17.008 1.00 31.75 O HETATM 4234 O HOH B 169 13.645 -62.709 5.753 0.92 26.62 O HETATM 4235 O HOH B 170 6.310 -63.361 4.144 1.00 37.08 O HETATM 4236 O HOH B 171 -4.350 -61.453 3.816 0.97 33.80 O HETATM 4237 O HOH B 172 12.179 -71.544 13.472 0.86 32.60 O HETATM 4238 O HOH B 174 21.176 -67.572 35.510 0.95 32.84 O HETATM 4239 O HOH B 175 11.241 -73.375 20.191 1.00 30.73 O HETATM 4240 O HOH B 178 18.369 -68.856 24.530 0.91 29.25 O HETATM 4241 O HOH B 179 13.586 -66.826 41.538 1.00 34.05 O HETATM 4242 O HOH B 181 16.393 -71.710 17.485 0.88 33.25 O HETATM 4243 O HOH B 185 11.569 -47.056 27.992 1.00 35.70 O HETATM 4244 O HOH B 192 -3.804 -49.856 39.259 0.93 32.23 O HETATM 4245 O HOH B 193 13.825 -72.929 20.310 1.00 31.95 O HETATM 4246 O HOH B 196 21.622 -60.630 33.950 0.90 36.35 O HETATM 4247 O HOH B 199 5.618 -62.604 43.275 0.88 28.22 O HETATM 4248 O HOH B 203 4.193 -40.084 34.081 0.97 37.49 O HETATM 4249 O HOH B 205 -1.490 -49.062 27.259 0.98 34.48 O HETATM 4250 O HOH B 206 11.234 -66.397 -0.294 1.00 31.72 O HETATM 4251 O HOH B 207 18.836 -59.941 35.475 0.97 34.60 O HETATM 4252 O HOH B 208 16.675 -74.025 24.091 0.91 31.98 O HETATM 4253 O HOH B 213 23.164 -56.645 23.674 0.91 35.82 O HETATM 4254 O HOH B 215 -3.331 -51.601 13.913 0.93 30.78 O HETATM 4255 O HOH B 216 1.183 -49.968 26.149 0.89 35.44 O HETATM 4256 O HOH B 218 -4.414 -72.394 15.678 0.89 33.76 O HETATM 4257 O HOH B 219 9.572 -62.820 46.230 0.96 38.11 O HETATM 4258 O HOH B 224 10.070 -73.011 15.145 1.00 36.45 O HETATM 4259 O HOH B 228 22.076 -67.954 27.283 0.96 39.66 O HETATM 4260 O HOH B 229 -2.850 -69.590 9.687 1.00 39.52 O HETATM 4261 O HOH B 236 19.882 -67.691 17.836 0.83 35.31 O HETATM 4262 O HOH B 237 19.202 -49.029 28.262 0.79 38.13 O HETATM 4263 O HOH B 239 12.469 -46.453 30.868 1.00 43.08 O HETATM 4264 O HOH B 241 3.486 -67.233 6.455 0.92 37.14 O HETATM 4265 O HOH B 242 19.636 -64.479 14.987 0.94 37.30 O HETATM 4266 O HOH B 243 23.317 -65.662 21.564 1.00 46.92 O HETATM 4267 O HOH B 245 12.861 -67.760 0.880 0.89 35.19 O HETATM 4268 O HOH B 247 7.337 -65.951 -2.049 0.90 35.10 O HETATM 4269 O HOH B 252 16.769 -68.737 14.475 0.93 37.48 O HETATM 4270 O HOH B 260 2.371 -63.014 4.571 0.86 32.94 O HETATM 4271 O AHOH B 263 -0.284 -49.696 31.524 0.58 14.21 O HETATM 4272 O BHOH B 263 0.659 -49.510 32.093 0.42 16.08 O HETATM 4273 O HOH B 265 16.452 -68.730 28.807 0.75 19.89 O HETATM 4274 O HOH B 267 20.091 -59.779 19.367 0.79 22.23 O HETATM 4275 O HOH B 269 -1.393 -68.333 37.086 0.69 24.39 O HETATM 4276 O AHOH B 270 15.012 -68.145 11.676 0.57 23.95 O HETATM 4277 O BHOH B 270 14.679 -66.672 10.608 0.43 26.59 O MASTER 325 0 0 9 14 0 0 6 2106 2 0 19 END
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Related entries of code: 3f1p
Entries with 90% protein sequence similarity cutoff in PDBbind
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Protein Sequence Similarity
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121aa, >4GHI_2|Chain... at 100%
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121aa, >4GS9_2|Chain... at 100%
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PDBbind
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PDBbind
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PDBbind
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Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
3f1p
Complex Type
Protein-Protein
PDBbind Subset
general set
Protein Name
Endothelial PAS domain-containing protein 1, HIF2alpha C-terminal PAS domain
Ligand Name
121-mer
EC.Number
E.C.-.-.-.-
Resolution
1.17(Å)
Affinity (Kd/Ki/IC50)
Kd=120uM
Release Year
2009
Protein/NA Sequence
Check fasta file
Primary Reference
(2009) Proc.Natl.Acad.Sci.USA Vol. 106: pp. 450-455
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q99814
P27540
Entrez Gene ID
NCBI Entrez Gene ID:
2034
405
ASD
Information of known allosteric effects of PDB entries
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