Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 07-FEB-09 3G6P TITLE GR DNA BINDING DOMAIN:FKBP5 COMPLEX, 18BP COMPND MOL_ID: 1; COMPND 2 MOLECULE: DNA (5'- COMPND 3 D(*CP*CP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*TP*G)-3'); COMPND 4 CHAIN: C; COMPND 5 ENGINEERED: YES; COMPND 6 OTHER_DETAILS: GR BINDING SITE FKBP5 TOP STRAND; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'- COMPND 9 D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*TP*G)-3'); COMPND 10 CHAIN: D; COMPND 11 ENGINEERED: YES; COMPND 12 OTHER_DETAILS: GR BINDING SITE FKBP5 BOTTOM STRAND; COMPND 13 MOL_ID: 3; COMPND 14 MOLECULE: GLUCOCORTICOID RECEPTOR; COMPND 15 CHAIN: A, B; COMPND 16 FRAGMENT: UNP RESIDUES 440-525; COMPND 17 SYNONYM: GR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1; COMPND 18 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 MOL_ID: 2; SOURCE 4 SYNTHETIC: YES; SOURCE 5 MOL_ID: 3; SOURCE 6 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; SOURCE 7 ORGANISM_COMMON: BROWN RAT,RAT,RATS; SOURCE 8 ORGANISM_TAXID: 10116; SOURCE 9 GENE: GRL, NR3C1; SOURCE 10 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 11 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 12 EXPRESSION_SYSTEM_STRAIN: BL21(DE3) GOLD; SOURCE 13 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 14 EXPRESSION_SYSTEM_PLASMID: PET28A KEYWDS GLUCOCORTICOID, DNA-BINDING, ALLOSTERY, LEVER ARM, TRANSCRIPTION, KEYWDS 2 HORMONE, ALTERNATIVE INITIATION, CHROMATIN REGULATOR, CYTOPLASM, KEYWDS 3 LIPID-BINDING, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, KEYWDS 4 RECEPTOR, STEROID-BINDING, TRANSCRIPTION REGULATION, UBL KEYWDS 5 CONJUGATION, ZINC, ZINC-FINGER, TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR M.A.PUFALL,K.R.YAMAMOTO,S.H.MEIJSING REVDAT 3 01-NOV-17 3G6P 1 REMARK REVDAT 2 02-JUN-09 3G6P 1 JRNL REVDAT 1 21-APR-09 3G6P 0 JRNL AUTH S.H.MEIJSING,M.A.PUFALL,A.Y.SO,D.L.BATES,L.CHEN,K.R.YAMAMOTO JRNL TITL DNA BINDING SITE SEQUENCE DIRECTS GLUCOCORTICOID RECEPTOR JRNL TITL 2 STRUCTURE AND ACTIVITY. JRNL REF SCIENCE V. 324 407 2009 JRNL REFN ISSN 0036-8075 JRNL PMID 19372434 JRNL DOI 10.1126/SCIENCE.1164265 REMARK 2 REMARK 2 RESOLUTION. 1.99 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (PHENIX.REFINE) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.99 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 28.69 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.990 REMARK 3 COMPLETENESS FOR RANGE (%) : 98.0 REMARK 3 NUMBER OF REFLECTIONS : 30728 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.216 REMARK 3 R VALUE (WORKING SET) : 0.214 REMARK 3 FREE R VALUE : 0.239 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 6.510 REMARK 3 FREE R VALUE TEST SET COUNT : 2000 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 28.6967 - 4.2714 0.99 3107 216 0.1781 0.2082 REMARK 3 2 4.2714 - 3.3921 0.99 2959 207 0.1782 0.1908 REMARK 3 3 3.3921 - 2.9638 0.98 2875 200 0.2019 0.2319 REMARK 3 4 2.9638 - 2.6930 0.99 2913 203 0.2125 0.2274 REMARK 3 5 2.6930 - 2.5001 1.00 2894 201 0.2155 0.2895 REMARK 3 6 2.5001 - 2.3528 0.99 2894 201 0.2218 0.2564 REMARK 3 7 2.3528 - 2.2350 1.00 2882 201 0.2313 0.2808 REMARK 3 8 2.2350 - 2.1377 1.00 2879 200 0.2719 0.2986 REMARK 3 9 2.1377 - 2.0555 1.00 2844 198 0.3257 0.3728 REMARK 3 10 2.0555 - 1.9850 0.86 2481 173 0.4198 0.3992 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : 0.35 REMARK 3 B_SOL : 52.54 REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.000 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : NULL REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 39.80 REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.008 NULL REMARK 3 ANGLE : NULL NULL REMARK 3 CHIRALITY : NULL NULL REMARK 3 PLANARITY : NULL NULL REMARK 3 DIHEDRAL : NULL NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 4 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: CHAIN A REMARK 3 ORIGIN FOR THE GROUP (A): -13.9439 17.9333 -20.7017 REMARK 3 T TENSOR REMARK 3 T11: 0.3963 T22: 0.3629 REMARK 3 T33: 0.3680 T12: -0.0901 REMARK 3 T13: -0.0090 T23: -0.0315 REMARK 3 L TENSOR REMARK 3 L11: 0.7334 L22: 1.8088 REMARK 3 L33: 1.6279 L12: 0.3596 REMARK 3 L13: -0.3009 L23: 0.9762 REMARK 3 S TENSOR REMARK 3 S11: -0.0380 S12: 0.2799 S13: 0.0908 REMARK 3 S21: -0.5860 S22: 0.1579 S23: 0.0262 REMARK 3 S31: -0.3637 S32: -0.1467 S33: -0.1090 REMARK 3 TLS GROUP : 2 REMARK 3 SELECTION: CHAIN B REMARK 3 ORIGIN FOR THE GROUP (A): -8.9641 17.8241 7.3014 REMARK 3 T TENSOR REMARK 3 T11: 0.2318 T22: 0.3536 REMARK 3 T33: 0.3791 T12: 0.0320 REMARK 3 T13: 0.0486 T23: 0.0869 REMARK 3 L TENSOR REMARK 3 L11: 0.7369 L22: 1.2606 REMARK 3 L33: 2.2909 L12: 0.7929 REMARK 3 L13: 0.9952 L23: -1.2453 REMARK 3 S TENSOR REMARK 3 S11: -0.0208 S12: -0.2090 S13: -0.1101 REMARK 3 S21: 0.1010 S22: 0.3404 S23: 0.1984 REMARK 3 S31: 0.0140 S32: -0.4165 S33: -0.3168 REMARK 3 TLS GROUP : 3 REMARK 3 SELECTION: CHAIN C REMARK 3 ORIGIN FOR THE GROUP (A): -10.8625 2.1497 -9.2445 REMARK 3 T TENSOR REMARK 3 T11: 0.8908 T22: 0.3781 REMARK 3 T33: 0.3781 T12: -0.1370 REMARK 3 T13: -0.1101 T23: 0.0113 REMARK 3 L TENSOR REMARK 3 L11: 1.0800 L22: -0.1709 REMARK 3 L33: 0.9625 L12: -0.5839 REMARK 3 L13: 0.9821 L23: 0.4390 REMARK 3 S TENSOR REMARK 3 S11: 0.4136 S12: 0.0346 S13: -0.3841 REMARK 3 S21: -0.0278 S22: 0.1647 S23: -0.0485 REMARK 3 S31: 0.8535 S32: 0.0151 S33: -0.4601 REMARK 3 TLS GROUP : 4 REMARK 3 SELECTION: CHAIN D REMARK 3 ORIGIN FOR THE GROUP (A): -9.4683 2.3157 -5.8382 REMARK 3 T TENSOR REMARK 3 T11: 0.7831 T22: 0.4164 REMARK 3 T33: 0.3588 T12: -0.0685 REMARK 3 T13: -0.0097 T23: -0.0334 REMARK 3 L TENSOR REMARK 3 L11: 0.9274 L22: -0.1574 REMARK 3 L33: 0.5877 L12: -0.8391 REMARK 3 L13: 0.8375 L23: 0.2650 REMARK 3 S TENSOR REMARK 3 S11: 0.2236 S12: -0.0553 S13: -0.3005 REMARK 3 S21: 0.2502 S22: 0.1578 S23: 0.1099 REMARK 3 S31: 0.9482 S32: -0.2170 S33: -0.2491 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 3G6P COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 16-FEB-09. REMARK 100 THE DEPOSITION ID IS D_1000051491. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 10-APR-08 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 6.0 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : ALS REMARK 200 BEAMLINE : 8.3.1 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.115894 REMARK 200 MONOCHROMATOR : DOUBLE FLAT CRYSTAL, SI(111) REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM Q315R REMARK 200 INTENSITY-INTEGRATION SOFTWARE : XDS REMARK 200 DATA SCALING SOFTWARE : XSCALE REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 30730 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.980 REMARK 200 RESOLUTION RANGE LOW (A) : 50.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 98.0 REMARK 200 DATA REDUNDANCY : NULL REMARK 200 R MERGE (I) : 0.07900 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 14.0300 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.98 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.04 REMARK 200 COMPLETENESS FOR SHELL (%) : 83.3 REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : 0.03100 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 0.380 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHENIX REMARK 200 STARTING MODEL: PDB ENTRY 1GLU REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 65.39 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.55 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 50MM NA CACODYLATE PH 6.0, 1MM REMARK 280 SPERMIDINE, 20MM MGCL2, 2MM CACL2, 10% 1,5-HEXANEDIOL, VAPOR REMARK 280 DIFFUSION, HANGING DROP, TEMPERATURE 298K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 21 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X+1/2,-Y,Z+1/2 REMARK 290 3555 -X,Y+1/2,-Z+1/2 REMARK 290 4555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 19.53000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 56.20500 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 50.05500 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 56.20500 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 19.53000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 50.05500 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 6380 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 12900 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -29.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: C, D, A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLY A 436 REMARK 465 LYS A 511 REMARK 465 THR A 512 REMARK 465 LYS A 513 REMARK 465 LYS A 514 REMARK 465 LYS A 515 REMARK 465 ILE A 516 REMARK 465 LYS A 517 REMARK 465 GLY A 518 REMARK 465 ILE A 519 REMARK 465 GLN A 520 REMARK 465 GLN A 521 REMARK 465 ALA A 522 REMARK 465 THR A 523 REMARK 465 ALA A 524 REMARK 465 GLY A 525 REMARK 465 GLY B 436 REMARK 465 GLY B 518 REMARK 465 ILE B 519 REMARK 465 GLN B 520 REMARK 465 GLN B 521 REMARK 465 ALA B 522 REMARK 465 THR B 523 REMARK 465 ALA B 524 REMARK 465 GLY B 525 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 SER A 437 OG REMARK 470 SER B 437 OG REMARK 470 LYS B 514 CG CD CE NZ REMARK 470 LYS B 515 CG CD CE NZ REMARK 470 ILE B 516 CG1 CG2 CD1 REMARK 470 LYS B 517 CG CD CE NZ REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DC C 1 O4' - C1' - N1 ANGL. DEV. = 3.8 DEGREES REMARK 500 DA C 6 O4' - C1' - N9 ANGL. DEV. = -5.0 DEGREES REMARK 500 DC C 10 O5' - C5' - C4' ANGL. DEV. = -4.8 DEGREES REMARK 500 DC C 11 C3' - O3' - P ANGL. DEV. = 7.5 DEGREES REMARK 500 DT C 12 O4' - C1' - N1 ANGL. DEV. = -4.4 DEGREES REMARK 500 DG C 13 C3' - C2' - C1' ANGL. DEV. = -5.9 DEGREES REMARK 500 DG C 13 O4' - C1' - N9 ANGL. DEV. = 6.3 DEGREES REMARK 500 DC C 16 O4' - C1' - N1 ANGL. DEV. = -5.5 DEGREES REMARK 500 DT C 17 O4' - C1' - N1 ANGL. DEV. = -4.9 DEGREES REMARK 500 DG C 18 O4' - C1' - N9 ANGL. DEV. = -5.7 DEGREES REMARK 500 DC D 1 O4' - C1' - N1 ANGL. DEV. = -4.5 DEGREES REMARK 500 DC D 2 O5' - C5' - C4' ANGL. DEV. = -6.2 DEGREES REMARK 500 DC D 2 O4' - C1' - N1 ANGL. DEV. = 3.6 DEGREES REMARK 500 DG D 4 O5' - C5' - C4' ANGL. DEV. = -5.0 DEGREES REMARK 500 DG D 4 O4' - C1' - N9 ANGL. DEV. = 1.9 DEGREES REMARK 500 DA D 5 O4' - C1' - N9 ANGL. DEV. = -4.7 DEGREES REMARK 500 DG D 10 O4' - C1' - N9 ANGL. DEV. = 3.5 DEGREES REMARK 500 DT D 12 O4' - C1' - N1 ANGL. DEV. = -4.4 DEGREES REMARK 500 DT D 15 O4' - C1' - N1 ANGL. DEV. = -4.8 DEGREES REMARK 500 DC D 16 O4' - C1' - N1 ANGL. DEV. = -4.7 DEGREES REMARK 500 DT D 17 O4' - C1' - N1 ANGL. DEV. = -8.0 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 GLN A 471 46.89 35.29 REMARK 500 ASP B 481 38.11 -142.00 REMARK 500 ILE B 516 138.30 -173.99 REMARK 500 REMARK 500 REMARK: NULL REMARK 610 REMARK 610 MISSING HETEROATOM REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 610 I=INSERTION CODE): REMARK 610 M RES C SSEQI REMARK 610 ACT C 19 REMARK 610 ACT A 1 REMARK 610 ACT A 3 REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A1514 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 440 SG REMARK 620 2 CYS A 443 SG 112.5 REMARK 620 3 CYS A 457 SG 114.2 103.4 REMARK 620 4 CYS A 460 SG 113.4 113.0 99.3 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A1515 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 476 SG REMARK 620 2 CYS A 482 SG 102.5 REMARK 620 3 CYS A 492 SG 113.1 114.9 REMARK 620 4 CYS A 495 SG 107.5 112.5 106.3 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN B1512 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS B 440 SG REMARK 620 2 CYS B 443 SG 119.2 REMARK 620 3 CYS B 457 SG 116.5 103.4 REMARK 620 4 CYS B 460 SG 109.0 108.2 98.5 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN B1513 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS B 476 SG REMARK 620 2 CYS B 482 SG 101.6 REMARK 620 3 CYS B 492 SG 111.4 115.4 REMARK 620 4 CYS B 495 SG 107.6 112.5 108.0 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ACT C 19 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A1514 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A1515 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ACT A 1 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC5 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ACT A 3 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC6 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN B1512 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC7 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN B1513 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 3FYL RELATED DB: PDB REMARK 900 SAME PROTEIN, DIFFERENT DNA REMARK 900 RELATED ID: 3G6Q RELATED DB: PDB REMARK 900 SAME DNA BINDING SITE, INSERTION MUTATION GR GAMMA REMARK 900 RELATED ID: 3G6R RELATED DB: PDB REMARK 900 RELATED ID: 3G6T RELATED DB: PDB REMARK 900 RELATED ID: 3G6U RELATED DB: PDB REMARK 900 RELATED ID: 3G8X RELATED DB: PDB REMARK 900 RELATED ID: 3G97 RELATED DB: PDB REMARK 900 RELATED ID: 3G99 RELATED DB: PDB DBREF 3G6P B 440 525 UNP P06536 GCR_RAT 440 525 DBREF 3G6P A 440 525 UNP P06536 GCR_RAT 440 525 DBREF 3G6P C 1 18 PDB 3G6P 3G6P 1 18 DBREF 3G6P D 1 18 PDB 3G6P 3G6P 1 18 SEQADV 3G6P GLY B 436 UNP P06536 EXPRESSION TAG SEQADV 3G6P SER B 437 UNP P06536 EXPRESSION TAG SEQADV 3G6P HIS B 438 UNP P06536 EXPRESSION TAG SEQADV 3G6P MET B 439 UNP P06536 EXPRESSION TAG SEQADV 3G6P GLY A 436 UNP P06536 EXPRESSION TAG SEQADV 3G6P SER A 437 UNP P06536 EXPRESSION TAG SEQADV 3G6P HIS A 438 UNP P06536 EXPRESSION TAG SEQADV 3G6P MET A 439 UNP P06536 EXPRESSION TAG SEQRES 1 C 18 DC DC DA DG DA DA DC DA DC DC DC DT DG SEQRES 2 C 18 DT DT DC DT DG SEQRES 1 D 18 DC DC DA DG DA DA DC DA DG DG DG DT DG SEQRES 2 D 18 DT DT DC DT DG SEQRES 1 A 90 GLY SER HIS MET CYS LEU VAL CYS SER ASP GLU ALA SER SEQRES 2 A 90 GLY CYS HIS TYR GLY VAL LEU THR CYS GLY SER CYS LYS SEQRES 3 A 90 VAL PHE PHE LYS ARG ALA VAL GLU GLY GLN HIS ASN TYR SEQRES 4 A 90 LEU CYS ALA GLY ARG ASN ASP CYS ILE ILE ASP LYS ILE SEQRES 5 A 90 ARG ARG LYS ASN CYS PRO ALA CYS ARG TYR ARG LYS CYS SEQRES 6 A 90 LEU GLN ALA GLY MET ASN LEU GLU ALA ARG LYS THR LYS SEQRES 7 A 90 LYS LYS ILE LYS GLY ILE GLN GLN ALA THR ALA GLY SEQRES 1 B 90 GLY SER HIS MET CYS LEU VAL CYS SER ASP GLU ALA SER SEQRES 2 B 90 GLY CYS HIS TYR GLY VAL LEU THR CYS GLY SER CYS LYS SEQRES 3 B 90 VAL PHE PHE LYS ARG ALA VAL GLU GLY GLN HIS ASN TYR SEQRES 4 B 90 LEU CYS ALA GLY ARG ASN ASP CYS ILE ILE ASP LYS ILE SEQRES 5 B 90 ARG ARG LYS ASN CYS PRO ALA CYS ARG TYR ARG LYS CYS SEQRES 6 B 90 LEU GLN ALA GLY MET ASN LEU GLU ALA ARG LYS THR LYS SEQRES 7 B 90 LYS LYS ILE LYS GLY ILE GLN GLN ALA THR ALA GLY HET ACT C 19 3 HET ZN A1514 1 HET ZN A1515 1 HET ACT A 1 3 HET ACT A 3 3 HET ZN B1512 1 HET ZN B1513 1 HETNAM ACT ACETATE ION HETNAM ZN ZINC ION FORMUL 5 ACT 3(C2 H3 O2 1-) FORMUL 6 ZN 4(ZN 2+) FORMUL 12 HOH *115(H2 O) HELIX 1 1 CYS A 457 GLN A 471 1 15 HELIX 2 2 CYS A 492 GLY A 504 1 13 HELIX 3 3 CYS B 457 GLY B 470 1 14 HELIX 4 4 CYS B 492 ALA B 503 1 12 HELIX 5 5 GLU B 508 LYS B 514 1 7 SHEET 1 A 2 GLY A 449 HIS A 451 0 SHEET 2 A 2 VAL A 454 THR A 456 -1 O VAL A 454 N HIS A 451 SHEET 1 B 2 GLY B 449 HIS B 451 0 SHEET 2 B 2 VAL B 454 THR B 456 -1 O VAL B 454 N HIS B 451 LINK SG CYS A 440 ZN ZN A1514 1555 1555 2.35 LINK SG CYS A 443 ZN ZN A1514 1555 1555 2.44 LINK SG CYS A 457 ZN ZN A1514 1555 1555 2.37 LINK SG CYS A 460 ZN ZN A1514 1555 1555 2.34 LINK SG CYS A 476 ZN ZN A1515 1555 1555 2.33 LINK SG CYS A 482 ZN ZN A1515 1555 1555 2.24 LINK SG CYS A 492 ZN ZN A1515 1555 1555 2.33 LINK SG CYS A 495 ZN ZN A1515 1555 1555 2.37 LINK SG CYS B 440 ZN ZN B1512 1555 1555 2.23 LINK SG CYS B 443 ZN ZN B1512 1555 1555 2.36 LINK SG CYS B 457 ZN ZN B1512 1555 1555 2.35 LINK SG CYS B 460 ZN ZN B1512 1555 1555 2.33 LINK SG CYS B 476 ZN ZN B1513 1555 1555 2.31 LINK SG CYS B 482 ZN ZN B1513 1555 1555 2.28 LINK SG CYS B 492 ZN ZN B1513 1555 1555 2.37 LINK SG CYS B 495 ZN ZN B1513 1555 1555 2.33 CISPEP 1 ILE B 516 LYS B 517 0 -0.36 SITE 1 AC1 3 DA C 8 DC C 9 DG D 13 SITE 1 AC2 4 CYS A 440 CYS A 443 CYS A 457 CYS A 460 SITE 1 AC3 4 CYS A 476 CYS A 482 CYS A 492 CYS A 495 SITE 1 AC4 2 ASN A 491 HOH C 37 SITE 1 AC5 4 HOH A 66 ASP A 481 CYS A 482 ARG A 498 SITE 1 AC6 4 CYS B 440 CYS B 443 CYS B 457 CYS B 460 SITE 1 AC7 4 CYS B 476 CYS B 482 CYS B 492 CYS B 495 CRYST1 39.060 100.110 112.410 90.00 90.00 90.00 P 21 21 21 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.025602 0.000000 0.000000 0.00000 SCALE2 0.000000 0.009989 0.000000 0.00000 SCALE3 0.000000 0.000000 0.008896 0.00000 ATOM 1 O5' DC C 1 -5.401 8.051 -37.546 1.00 69.66 O ANISOU 1 O5' DC C 1 10162 10405 5901 1281 342 -1576 O ATOM 2 C5' DC C 1 -5.968 8.795 -38.621 1.00 70.59 C ANISOU 2 C5' DC C 1 10167 10682 5972 1281 506 -1488 C ATOM 3 C4' DC C 1 -7.409 9.150 -38.291 1.00 69.10 C ANISOU 3 C4' DC C 1 10086 10295 5875 1075 569 -1337 C ATOM 4 O4' DC C 1 -8.254 7.997 -38.570 1.00 65.68 O ANISOU 4 O4' DC C 1 9807 9701 5449 1147 356 -1420 O ATOM 5 C3' DC C 1 -7.679 9.509 -36.831 1.00 65.51 C ANISOU 5 C3' DC C 1 9724 9625 5540 843 607 -1225 C ATOM 6 O3' DC C 1 -8.857 10.300 -36.718 1.00 59.97 O ANISOU 6 O3' DC C 1 9045 8846 4894 652 745 -1062 O ATOM 7 C2' DC C 1 -7.925 8.135 -36.218 1.00 62.17 C ANISOU 7 C2' DC C 1 9497 8968 5157 877 340 -1327 C ATOM 8 C1' DC C 1 -8.736 7.480 -37.344 1.00 61.92 C ANISOU 8 C1' DC C 1 9508 8942 5076 997 235 -1388 C ATOM 9 N1 DC C 1 -8.621 6.005 -37.279 1.00 59.85 N ANISOU 9 N1 DC C 1 9388 8541 4812 1137 -59 -1548 N ATOM 10 C2 DC C 1 -9.776 5.206 -37.329 1.00 65.00 C ANISOU 10 C2 DC C 1 10197 8988 5512 1099 -215 -1548 C ATOM 11 O2 DC C 1 -10.880 5.744 -37.460 1.00 69.44 O ANISOU 11 O2 DC C 1 10772 9504 6107 957 -98 -1422 O ATOM 12 N3 DC C 1 -9.660 3.859 -37.243 1.00 65.20 N ANISOU 12 N3 DC C 1 10358 8869 5547 1221 -501 -1688 N ATOM 13 C4 DC C 1 -8.453 3.315 -37.085 1.00 71.13 C ANISOU 13 C4 DC C 1 11096 9676 6254 1379 -629 -1833 C ATOM 14 N4 DC C 1 -8.366 1.982 -36.987 1.00 69.81 N ANISOU 14 N4 DC C 1 11073 9353 6100 1499 -928 -1974 N ATOM 15 C5 DC C 1 -7.270 4.118 -37.023 1.00 72.27 C ANISOU 15 C5 DC C 1 11078 10040 6340 1422 -464 -1842 C ATOM 16 C6 DC C 1 -7.393 5.444 -37.117 0.64 62.50 C ANISOU 16 C6 DC C 1 9705 8941 5103 1293 -182 -1694 C ATOM 17 P DC C 2 -9.237 10.982 -35.324 0.72 59.82 P ANISOU 17 P DC C 2 9078 8661 4988 404 830 -921 P ATOM 18 OP1 DC C 2 -9.449 12.400 -35.661 1.00 57.35 O ANISOU 18 OP1 DC C 2 8630 8483 4677 300 1071 -782 O ATOM 19 OP2 DC C 2 -8.313 10.544 -34.252 1.00 61.82 O ANISOU 19 OP2 DC C 2 9372 8835 5283 410 734 -985 O ATOM 20 O5' DC C 2 -10.631 10.334 -34.908 1.00 63.32 O ANISOU 20 O5' DC C 2 9706 8866 5486 287 707 -881 O ATOM 21 C5' DC C 2 -11.798 10.396 -35.704 1.00 59.95 C ANISOU 21 C5' DC C 2 9307 8434 5036 267 733 -841 C ATOM 22 C4' DC C 2 -12.782 9.441 -35.043 1.00 60.63 C ANISOU 22 C4' DC C 2 9585 8273 5180 174 553 -840 C ATOM 23 O4' DC C 2 -12.261 8.105 -35.243 1.00 60.39 O ANISOU 23 O4' DC C 2 9635 8182 5127 348 320 -996 O ATOM 24 C3' DC C 2 -12.982 9.580 -33.526 1.00 56.87 C ANISOU 24 C3' DC C 2 9188 7629 4793 -27 542 -747 C ATOM 25 O3' DC C 2 -14.370 9.530 -33.246 1.00 60.79 O ANISOU 25 O3' DC C 2 9785 7990 5322 -186 524 -658 O ATOM 26 C2' DC C 2 -12.319 8.344 -32.932 1.00 55.57 C ANISOU 26 C2' DC C 2 9134 7334 4647 57 317 -858 C ATOM 27 C1' DC C 2 -12.549 7.362 -34.096 0.60 51.33 C ANISOU 27 C1' DC C 2 8645 6805 4054 238 163 -982 C ATOM 28 N1 DC C 2 -11.664 6.168 -34.051 1.00 57.15 N ANISOU 28 N1 DC C 2 9450 7488 4775 410 -64 -1140 N ATOM 29 C2 DC C 2 -12.222 4.894 -34.147 1.00 61.67 C ANISOU 29 C2 DC C 2 10180 7884 5367 457 -310 -1213 C ATOM 30 O2 DC C 2 -13.448 4.802 -34.297 1.00 66.45 O ANISOU 30 O2 DC C 2 10856 8391 6001 351 -321 -1142 O ATOM 31 N3 DC C 2 -11.406 3.807 -34.076 1.00 70.71 N ANISOU 31 N3 DC C 2 11396 8970 6499 618 -536 -1363 N ATOM 32 C4 DC C 2 -10.089 3.972 -33.915 1.00 67.89 C ANISOU 32 C4 DC C 2 10955 8739 6103 731 -511 -1445 C ATOM 33 N4 DC C 2 -9.306 2.889 -33.835 1.00 68.69 N ANISOU 33 N4 DC C 2 11133 8782 6183 895 -745 -1605 N ATOM 34 C5 DC C 2 -9.513 5.269 -33.811 1.00 63.58 C ANISOU 34 C5 DC C 2 10242 8379 5537 678 -251 -1369 C ATOM 35 C6 DC C 2 -10.324 6.328 -33.882 1.00 59.99 C ANISOU 35 C6 DC C 2 9722 7968 5104 517 -39 -1215 C ATOM 36 P DA C 3 -14.964 9.998 -31.850 0.82 58.24 P ANISOU 36 P DA C 3 9513 7543 5074 -423 566 -524 P ATOM 37 OP1 DA C 3 -15.749 11.211 -32.133 1.00 56.49 O ANISOU 37 OP1 DA C 3 9211 7414 4841 -537 760 -415 O ATOM 38 OP2 DA C 3 -13.910 10.015 -30.793 1.00 60.46 O ANISOU 38 OP2 DA C 3 9776 7797 5398 -432 547 -533 O ATOM 39 O5' DA C 3 -15.968 8.805 -31.484 1.00 60.60 O ANISOU 39 O5' DA C 3 9995 7632 5399 -493 359 -528 O ATOM 40 C5' DA C 3 -16.850 8.345 -32.482 1.00 58.02 C ANISOU 40 C5' DA C 3 9717 7292 5037 -444 303 -564 C ATOM 41 C4' DA C 3 -17.547 7.098 -31.991 1.00 53.90 C ANISOU 41 C4' DA C 3 9369 6555 4555 -507 78 -575 C ATOM 42 O4' DA C 3 -16.649 5.968 -32.114 1.00 59.22 O ANISOU 42 O4' DA C 3 10106 7164 5233 -338 -123 -706 O ATOM 43 C3' DA C 3 -17.988 7.132 -30.553 1.00 55.66 C ANISOU 43 C3' DA C 3 9665 6649 4835 -722 54 -457 C ATOM 44 O3' DA C 3 -19.184 6.371 -30.396 1.00 61.88 O ANISOU 44 O3' DA C 3 10585 7285 5643 -835 -81 -418 O ATOM 45 C2' DA C 3 -16.809 6.463 -29.838 1.00 63.43 C ANISOU 45 C2' DA C 3 10690 7561 5850 -645 -77 -520 C ATOM 46 C1' DA C 3 -16.332 5.430 -30.857 1.00 61.91 C ANISOU 46 C1' DA C 3 10542 7354 5628 -425 -245 -678 C ATOM 47 N9 DA C 3 -14.891 5.155 -30.809 1.00 61.68 N ANISOU 47 N9 DA C 3 10476 7374 5584 -256 -300 -792 N ATOM 48 C8 DA C 3 -13.884 6.083 -30.771 1.00 61.81 C ANISOU 48 C8 DA C 3 10348 7560 5578 -203 -130 -800 C ATOM 49 N7 DA C 3 -12.682 5.560 -30.720 1.00 63.31 N ANISOU 49 N7 DA C 3 10534 7768 5751 -46 -230 -922 N ATOM 50 C5 DA C 3 -12.915 4.193 -30.745 1.00 65.24 C ANISOU 50 C5 DA C 3 10938 7840 6009 15 -492 -1002 C ATOM 51 C6 DA C 3 -12.049 3.086 -30.716 0.74 64.29 C ANISOU 51 C6 DA C 3 10899 7648 5879 181 -718 -1152 C ATOM 52 N6 DA C 3 -10.724 3.222 -30.663 1.00 59.65 N ANISOU 52 N6 DA C 3 10233 7178 5254 321 -697 -1254 N ATOM 53 N1 DA C 3 -12.591 1.846 -30.744 1.00 66.04 N ANISOU 53 N1 DA C 3 11287 7676 6131 197 -972 -1196 N ATOM 54 C2 DA C 3 -13.920 1.724 -30.794 1.00 58.75 C ANISOU 54 C2 DA C 3 10436 6644 5244 49 -988 -1094 C ATOM 55 N3 DA C 3 -14.835 2.695 -30.830 1.00 67.15 N ANISOU 55 N3 DA C 3 11430 7772 6311 -111 -781 -957 N ATOM 56 C4 DA C 3 -14.268 3.919 -30.796 1.00 64.19 C ANISOU 56 C4 DA C 3 10897 7584 5907 -118 -540 -919 C ATOM 57 P DG C 4 -19.977 6.368 -29.001 1.00 65.94 P ANISOU 57 P DG C 4 11174 7681 6199 -1082 -110 -277 P ATOM 58 OP1 DG C 4 -21.423 6.279 -29.286 0.73 66.41 O ANISOU 58 OP1 DG C 4 11287 7702 6244 -1206 -119 -220 O ATOM 59 OP2 DG C 4 -19.471 7.461 -28.154 1.00 63.51 O ANISOU 59 OP2 DG C 4 10760 7469 5900 -1158 55 -202 O ATOM 60 O5' DG C 4 -19.525 5.001 -28.330 1.00 63.60 O ANISOU 60 O5' DG C 4 11021 7193 5950 -1060 -362 -316 O ATOM 61 C5' DG C 4 -19.833 3.761 -28.938 1.00 67.46 C ANISOU 61 C5' DG C 4 11632 7549 6451 -982 -577 -395 C ATOM 62 C4' DG C 4 -19.134 2.675 -28.138 1.00 67.85 C ANISOU 62 C4' DG C 4 11803 7432 6547 -956 -798 -428 C ATOM 63 O4' DG C 4 -17.722 2.842 -28.374 1.00 71.26 O ANISOU 63 O4' DG C 4 12160 7959 6958 -762 -768 -543 O ATOM 64 C3' DG C 4 -19.314 2.717 -26.620 1.00 79.36 C ANISOU 64 C3' DG C 4 13309 8802 8040 -1158 -810 -292 C ATOM 65 O3' DG C 4 -19.854 1.454 -26.202 1.00 97.64 O ANISOU 65 O3' DG C 4 15795 10905 10399 -1239 -1056 -262 O ATOM 66 C2' DG C 4 -17.908 2.961 -26.060 1.00 70.76 C ANISOU 66 C2' DG C 4 12168 7762 6956 -1054 -776 -346 C ATOM 67 C1' DG C 4 -17.047 2.451 -27.216 1.00 70.70 C ANISOU 67 C1' DG C 4 12153 7789 6923 -799 -862 -525 C ATOM 68 N9 DG C 4 -15.708 3.018 -27.260 0.69 66.14 N ANISOU 68 N9 DG C 4 11461 7349 6319 -652 -756 -609 N ATOM 69 C8 DG C 4 -15.360 4.346 -27.241 1.00 55.97 C ANISOU 69 C8 DG C 4 10009 6245 5010 -669 -505 -568 C ATOM 70 N7 DG C 4 -14.068 4.527 -27.271 1.00 57.48 N ANISOU 70 N7 DG C 4 10128 6527 5185 -521 -473 -664 N ATOM 71 C5 DG C 4 -13.532 3.245 -27.320 1.00 60.81 C ANISOU 71 C5 DG C 4 10674 6823 5609 -390 -718 -785 C ATOM 72 C6 DG C 4 -12.189 2.798 -27.369 1.00 59.38 C ANISOU 72 C6 DG C 4 10488 6671 5404 -198 -811 -936 C ATOM 73 O6 DG C 4 -11.153 3.471 -27.390 1.00 59.71 O ANISOU 73 O6 DG C 4 10403 6866 5418 -106 -680 -990 O ATOM 74 N1 DG C 4 -12.092 1.407 -27.401 1.00 62.37 N ANISOU 74 N1 DG C 4 11028 6878 5792 -109 -1094 -1033 N ATOM 75 C2 DG C 4 -13.161 0.545 -27.393 1.00 69.12 C ANISOU 75 C2 DG C 4 12030 7547 6685 -202 -1269 -982 C ATOM 76 N2 DG C 4 -12.878 -0.765 -27.434 1.00 72.05 N ANISOU 76 N2 DG C 4 12549 7756 7069 -93 -1554 -1091 N ATOM 77 N3 DG C 4 -14.423 0.948 -27.342 1.00 69.55 N ANISOU 77 N3 DG C 4 12085 7577 6763 -390 -1177 -836 N ATOM 78 C4 DG C 4 -14.533 2.304 -27.309 1.00 68.43 C ANISOU 78 C4 DG C 4 11788 7609 6602 -470 -900 -750 C ATOM 79 P DA C 5 -19.972 1.005 -24.659 1.00 89.26 P ANISOU 79 P DA C 5 14832 9704 9379 -1422 -1161 -134 P ATOM 80 OP1 DA C 5 -21.292 0.348 -24.516 0.57 89.14 O ANISOU 80 OP1 DA C 5 14924 9560 9384 -1600 -1285 -33 O ATOM 81 OP2 DA C 5 -19.594 2.117 -23.765 1.00 79.01 O ANISOU 81 OP2 DA C 5 13415 8537 8067 -1495 -960 -57 O ATOM 82 O5' DA C 5 -18.821 -0.099 -24.542 1.00 84.09 O ANISOU 82 O5' DA C 5 14286 8910 8754 -1255 -1388 -255 O ATOM 83 C5' DA C 5 -18.618 -1.033 -25.613 1.00 74.07 C ANISOU 83 C5' DA C 5 13090 7561 7491 -1076 -1575 -402 C ATOM 84 C4' DA C 5 -17.463 -1.912 -25.185 1.00 76.91 C ANISOU 84 C4' DA C 5 13547 7805 7872 -942 -1775 -503 C ATOM 85 O4' DA C 5 -16.232 -1.157 -25.321 1.00 75.90 O ANISOU 85 O4' DA C 5 13288 7849 7701 -781 -1622 -603 O ATOM 86 C3' DA C 5 -17.513 -2.311 -23.714 1.00 75.12 C ANISOU 86 C3' DA C 5 13424 7433 7684 -1113 -1867 -376 C ATOM 87 O3' DA C 5 -16.864 -3.542 -23.585 1.00 82.94 O ANISOU 87 O3' DA C 5 14565 8243 8705 -1001 -2145 -472 O ATOM 88 C2' DA C 5 -16.682 -1.233 -23.031 1.00 64.61 C ANISOU 88 C2' DA C 5 11959 6262 6326 -1102 -1647 -360 C ATOM 89 C1' DA C 5 -15.577 -1.066 -24.069 1.00 72.55 C ANISOU 89 C1' DA C 5 12883 7390 7293 -837 -1614 -555 C ATOM 90 N9 DA C 5 -14.888 0.222 -24.056 1.00 64.36 N ANISOU 90 N9 DA C 5 11664 6569 6220 -788 -1349 -569 N ATOM 91 C8 DA C 5 -15.483 1.448 -24.067 1.00 60.54 C ANISOU 91 C8 DA C 5 11044 6236 5723 -909 -1099 -461 C ATOM 92 N7 DA C 5 -14.635 2.448 -24.070 1.00 62.28 N ANISOU 92 N7 DA C 5 11116 6626 5921 -833 -907 -498 N ATOM 93 C5 DA C 5 -13.390 1.839 -24.060 1.00 57.04 C ANISOU 93 C5 DA C 5 10488 5934 5250 -650 -1029 -643 C ATOM 94 C6 DA C 5 -12.081 2.363 -24.064 0.81 53.05 C ANISOU 94 C6 DA C 5 9873 5563 4720 -502 -930 -746 C ATOM 95 N6 DA C 5 -11.799 3.674 -24.064 1.00 56.40 N ANISOU 95 N6 DA C 5 10123 6170 5135 -524 -677 -706 N ATOM 96 N1 DA C 5 -11.069 1.479 -24.058 1.00 60.90 N ANISOU 96 N1 DA C 5 10944 6494 5701 -332 -1110 -896 N ATOM 97 C2 DA C 5 -11.341 0.171 -24.040 1.00 60.18 C ANISOU 97 C2 DA C 5 11033 6208 5626 -310 -1379 -936 C ATOM 98 N3 DA C 5 -12.527 -0.432 -24.039 1.00 63.90 N ANISOU 98 N3 DA C 5 11620 6528 6130 -445 -1500 -839 N ATOM 99 C4 DA C 5 -13.525 0.466 -24.049 1.00 57.77 C ANISOU 99 C4 DA C 5 10759 5830 5361 -615 -1306 -693 C ATOM 100 P DA C 6 -17.139 -4.436 -22.299 1.00100.12 P ANISOU 100 P DA C 6 16910 10197 10932 -1172 -2346 -346 P ATOM 101 OP1 DA C 6 -17.508 -5.779 -22.818 1.00 99.17 O ANISOU 101 OP1 DA C 6 16959 9863 10860 -1134 -2653 -399 O ATOM 102 OP2 DA C 6 -18.034 -3.674 -21.394 1.00 87.29 O ANISOU 102 OP2 DA C 6 15225 8636 9304 -1427 -2167 -139 O ATOM 103 O5' DA C 6 -15.688 -4.531 -21.637 1.00 68.71 O ANISOU 103 O5' DA C 6 12945 6219 6942 -1027 -2382 -446 O ATOM 104 C5' DA C 6 -14.701 -4.961 -22.551 1.00 73.23 C ANISOU 104 C5' DA C 6 13525 6809 7492 -759 -2494 -665 C ATOM 105 C4' DA C 6 -13.321 -4.739 -22.004 1.00 70.10 C ANISOU 105 C4' DA C 6 13093 6478 7066 -619 -2456 -768 C ATOM 106 O4' DA C 6 -13.006 -3.336 -22.057 1.00 66.83 O ANISOU 106 O4' DA C 6 12474 6307 6611 -614 -2137 -753 O ATOM 107 C3' DA C 6 -13.178 -5.158 -20.560 1.00 80.35 C ANISOU 107 C3' DA C 6 14506 7628 8397 -743 -2552 -665 C ATOM 108 O3' DA C 6 -12.205 -6.175 -20.580 1.00 82.14 O ANISOU 108 O3' DA C 6 14861 7727 8620 -557 -2805 -830 O ATOM 109 C2' DA C 6 -12.738 -3.890 -19.810 1.00 76.32 C ANISOU 109 C2' DA C 6 13833 7303 7862 -792 -2263 -605 C ATOM 110 C1' DA C 6 -12.248 -2.971 -20.927 1.00 69.57 C ANISOU 110 C1' DA C 6 12797 6677 6959 -633 -2062 -729 C ATOM 111 N9 DA C 6 -12.519 -1.546 -20.798 1.00 62.59 N ANISOU 111 N9 DA C 6 11726 5993 6062 -732 -1749 -629 N ATOM 112 C8 DA C 6 -13.738 -0.945 -20.659 0.82 59.26 C ANISOU 112 C8 DA C 6 11254 5608 5654 -939 -1616 -457 C ATOM 113 N7 DA C 6 -13.684 0.369 -20.596 1.00 59.20 N ANISOU 113 N7 DA C 6 11071 5793 5630 -975 -1349 -412 N ATOM 114 C5 DA C 6 -12.337 0.655 -20.712 1.00 54.18 C ANISOU 114 C5 DA C 6 10359 5252 4973 -786 -1295 -557 C ATOM 115 C6 DA C 6 -11.620 1.861 -20.736 1.00 53.23 C ANISOU 115 C6 DA C 6 10058 5330 4837 -727 -1058 -588 C ATOM 116 N6 DA C 6 -12.184 3.067 -20.622 1.00 48.89 N ANISOU 116 N6 DA C 6 9368 4913 4293 -852 -830 -472 N ATOM 117 N1 DA C 6 -10.282 1.792 -20.877 1.00 62.39 N ANISOU 117 N1 DA C 6 11182 6548 5974 -533 -1073 -747 N ATOM 118 C2 DA C 6 -9.710 0.591 -20.992 1.00 64.77 C ANISOU 118 C2 DA C 6 11625 6721 6263 -397 -1315 -877 C ATOM 119 N3 DA C 6 -10.279 -0.612 -20.984 1.00 68.57 N ANISOU 119 N3 DA C 6 12289 7003 6761 -428 -1563 -866 N ATOM 120 C4 DA C 6 -11.608 -0.513 -20.843 1.00 63.98 C ANISOU 120 C4 DA C 6 11736 6364 6209 -633 -1536 -696 C ATOM 121 P DC C 7 -11.843 -6.950 -19.243 1.00 93.97 P ANISOU 121 P DC C 7 16524 9030 10148 -621 -2989 -777 P ATOM 122 OP1 DC C 7 -11.415 -8.310 -19.638 1.00 91.84 O ANISOU 122 OP1 DC C 7 16437 8564 9893 -465 -3336 -927 O ATOM 123 OP2 DC C 7 -12.962 -6.751 -18.298 1.00 96.12 O ANISOU 123 OP2 DC C 7 16818 9245 10460 -909 -2921 -525 O ATOM 124 O5' DC C 7 -10.590 -6.116 -18.687 1.00 84.27 O ANISOU 124 O5' DC C 7 15172 7970 8875 -502 -2798 -865 O ATOM 125 C5' DC C 7 -9.479 -5.973 -19.550 1.00 88.41 C ANISOU 125 C5' DC C 7 15618 8629 9345 -242 -2782 -1093 C ATOM 126 C4' DC C 7 -8.533 -4.904 -19.073 1.00 80.37 C ANISOU 126 C4' DC C 7 14439 7807 8292 -181 -2533 -1135 C ATOM 127 O4' DC C 7 -9.208 -3.629 -19.173 1.00 79.69 O ANISOU 127 O4' DC C 7 14173 7895 8212 -324 -2232 -994 O ATOM 128 C3' DC C 7 -8.087 -5.067 -17.627 1.00 87.76 C ANISOU 128 C3' DC C 7 15450 8646 9247 -240 -2568 -1081 C ATOM 129 O3' DC C 7 -6.694 -5.369 -17.606 1.00 90.93 O ANISOU 129 O3' DC C 7 15870 9074 9604 -8 -2652 -1296 O ATOM 130 C2' DC C 7 -8.414 -3.731 -16.944 1.00 83.68 C ANISOU 130 C2' DC C 7 14760 8289 8746 -397 -2255 -923 C ATOM 131 C1' DC C 7 -8.790 -2.800 -18.100 1.00 84.77 C ANISOU 131 C1' DC C 7 14724 8622 8863 -387 -2047 -928 C ATOM 132 N1 DC C 7 -9.900 -1.826 -17.797 1.00 71.95 N ANISOU 132 N1 DC C 7 12991 7080 7266 -613 -1829 -719 N ATOM 133 C2 DC C 7 -9.639 -0.456 -17.746 1.00 69.49 C ANISOU 133 C2 DC C 7 12475 6980 6946 -621 -1543 -698 C ATOM 134 O2 DC C 7 -8.479 -0.046 -17.935 1.00 68.38 O ANISOU 134 O2 DC C 7 12241 6959 6781 -453 -1462 -841 O ATOM 135 N3 DC C 7 -10.674 0.392 -17.482 1.00 68.62 N ANISOU 135 N3 DC C 7 12275 6943 6857 -817 -1371 -521 N ATOM 136 C4 DC C 7 -11.911 -0.083 -17.280 1.00 63.63 C ANISOU 136 C4 DC C 7 11740 6194 6242 -998 -1464 -372 C ATOM 137 N4 DC C 7 -12.900 0.790 -17.028 1.00 59.85 N ANISOU 137 N4 DC C 7 11161 5808 5769 -1179 -1293 -213 N ATOM 138 C5 DC C 7 -12.192 -1.476 -17.342 0.84 65.53 C ANISOU 138 C5 DC C 7 12183 6220 6495 -1002 -1746 -383 C ATOM 139 C6 DC C 7 -11.168 -2.296 -17.596 1.00 71.30 C ANISOU 139 C6 DC C 7 13009 6868 7215 -807 -1923 -557 C ATOM 140 P DA C 8 -5.887 -5.517 -16.224 1.00111.99 P ANISOU 140 P DA C 8 18603 11672 12277 7 -2685 -1308 P ATOM 141 OP1 DA C 8 -4.551 -6.056 -16.555 1.00109.67 O ANISOU 141 OP1 DA C 8 18352 11391 11924 274 -2830 -1569 O ATOM 142 OP2 DA C 8 -6.726 -6.145 -15.171 1.00 98.23 O ANISOU 142 OP2 DA C 8 17019 9717 10588 -197 -2818 -1115 O ATOM 143 O5' DA C 8 -5.691 -3.988 -15.828 1.00108.46 O ANISOU 143 O5' DA C 8 17922 11455 11831 -52 -2327 -1239 O ATOM 144 C5' DA C 8 -4.921 -3.152 -16.684 1.00102.64 C ANISOU 144 C5' DA C 8 17002 10947 11049 102 -2146 -1381 C ATOM 145 C4' DA C 8 -4.406 -2.021 -15.831 1.00 93.99 C ANISOU 145 C4' DA C 8 15748 9994 9968 70 -1895 -1342 C ATOM 146 O4' DA C 8 -5.483 -1.072 -15.665 1.00 88.63 O ANISOU 146 O4' DA C 8 14955 9386 9333 -141 -1687 -1132 O ATOM 147 C3' DA C 8 -4.027 -2.492 -14.429 1.00 94.22 C ANISOU 147 C3' DA C 8 15894 9886 10021 51 -1995 -1323 C ATOM 148 O3' DA C 8 -2.932 -1.734 -13.918 1.00 88.84 O ANISOU 148 O3' DA C 8 15081 9344 9330 158 -1833 -1422 O ATOM 149 C2' DA C 8 -5.321 -2.279 -13.643 1.00 92.60 C ANISOU 149 C2' DA C 8 15708 9606 9872 -210 -1942 -1063 C ATOM 150 C1' DA C 8 -5.831 -0.994 -14.287 1.00 89.00 C ANISOU 150 C1' DA C 8 15041 9352 9424 -288 -1670 -985 C ATOM 151 N9 DA C 8 -7.275 -0.792 -14.238 1.00 85.88 N ANISOU 151 N9 DA C 8 14645 8927 9060 -516 -1626 -770 N ATOM 152 C8 DA C 8 -8.279 -1.726 -14.226 1.00 82.74 C ANISOU 152 C8 DA C 8 14410 8353 8674 -645 -1816 -659 C ATOM 153 N7 DA C 8 -9.489 -1.216 -14.207 1.00 74.74 N ANISOU 153 N7 DA C 8 13338 7380 7679 -843 -1708 -478 N ATOM 154 C5 DA C 8 -9.248 0.152 -14.224 1.00 72.46 C ANISOU 154 C5 DA C 8 12838 7302 7391 -836 -1435 -474 C ATOM 155 C6 DA C 8 -10.109 1.260 -14.213 1.00 60.71 C ANISOU 155 C6 DA C 8 11201 5953 5915 -986 -1222 -334 C ATOM 156 N6 DA C 8 -11.445 1.157 -14.190 1.00 57.77 N ANISOU 156 N6 DA C 8 10865 5539 5545 -1179 -1243 -169 N ATOM 157 N1 DA C 8 -9.536 2.477 -14.226 1.00 51.98 N ANISOU 157 N1 DA C 8 9906 5030 4815 -928 -996 -375 N ATOM 158 C2 DA C 8 -8.200 2.599 -14.254 1.00 50.65 C ANISOU 158 C2 DA C 8 9690 4913 4641 -741 -970 -540 C ATOM 159 N3 DA C 8 -7.284 1.634 -14.264 1.00 58.93 N ANISOU 159 N3 DA C 8 10862 5860 5669 -584 -1147 -690 N ATOM 160 C4 DA C 8 -7.893 0.431 -14.248 1.00 72.11 C ANISOU 160 C4 DA C 8 12725 7339 7333 -640 -1380 -647 C ATOM 161 P DC C 9 -2.497 -1.933 -12.394 1.00103.18 P ANISOU 161 P DC C 9 16968 11064 11171 145 -1872 -1399 P ATOM 162 OP1 DC C 9 -1.040 -2.181 -12.361 1.00103.87 O ANISOU 162 OP1 DC C 9 17065 11192 11210 381 -1929 -1642 O ATOM 163 OP2 DC C 9 -3.430 -2.887 -11.752 1.00 99.67 O ANISOU 163 OP2 DC C 9 16720 10395 10753 -7 -2073 -1244 O ATOM 164 O5' DC C 9 -2.781 -0.486 -11.780 1.00 93.78 O ANISOU 164 O5' DC C 9 15564 10037 10031 17 -1568 -1258 O ATOM 165 C5' DC C 9 -2.295 0.644 -12.493 1.00 90.33 C ANISOU 165 C5' DC C 9 14913 9819 9588 85 -1339 -1329 C ATOM 166 C4' DC C 9 -2.768 1.915 -11.824 1.00 78.69 C ANISOU 166 C4' DC C 9 13264 8460 8174 -60 -1095 -1170 C ATOM 167 O4' DC C 9 -4.195 2.041 -12.003 1.00 75.27 O ANISOU 167 O4' DC C 9 12842 7995 7762 -265 -1075 -968 O ATOM 168 C3' DC C 9 -2.493 1.974 -10.327 1.00 81.04 C ANISOU 168 C3' DC C 9 13575 8708 8510 -81 -1088 -1129 C ATOM 169 O3' DC C 9 -1.720 3.146 -10.181 1.00 80.77 O ANISOU 169 O3' DC C 9 13334 8850 8503 -10 -870 -1196 O ATOM 170 C2' DC C 9 -3.883 2.053 -9.681 1.00 80.42 C ANISOU 170 C2' DC C 9 13523 8568 8466 -313 -1082 -884 C ATOM 171 C1' DC C 9 -4.795 2.517 -10.821 1.00 79.87 C ANISOU 171 C1' DC C 9 13382 8574 8391 -415 -996 -801 C ATOM 172 N1 DC C 9 -6.199 1.978 -10.808 1.00 73.28 N ANISOU 172 N1 DC C 9 12660 7628 7556 -609 -1100 -617 N ATOM 173 C2 DC C 9 -7.294 2.851 -10.963 1.00 70.08 C ANISOU 173 C2 DC C 9 12136 7323 7169 -780 -947 -456 C ATOM 174 O2 DC C 9 -7.089 4.074 -11.110 1.00 62.71 O ANISOU 174 O2 DC C 9 11012 6559 6257 -767 -732 -463 O ATOM 175 N3 DC C 9 -8.554 2.329 -10.954 1.00 53.40 N ANISOU 175 N3 DC C 9 10124 5117 5048 -955 -1045 -298 N ATOM 176 C4 DC C 9 -8.733 1.021 -10.812 1.00 65.30 C ANISOU 176 C4 DC C 9 11837 6433 6541 -970 -1284 -289 C ATOM 177 N4 DC C 9 -9.991 0.546 -10.818 1.00 70.23 N ANISOU 177 N4 DC C 9 12550 6973 7163 -1154 -1375 -127 N ATOM 178 C5 DC C 9 -7.625 0.131 -10.654 1.00 73.54 C ANISOU 178 C5 DC C 9 13007 7361 7572 -796 -1451 -449 C ATOM 179 C6 DC C 9 -6.390 0.642 -10.662 1.00 65.22 C ANISOU 179 C6 DC C 9 11855 6410 6516 -617 -1351 -614 C ATOM 180 P DC C 10 -1.270 3.778 -8.797 1.00 97.45 P ANISOU 180 P DC C 10 15354 11002 10671 -2 -762 -1178 P ATOM 181 OP1 DC C 10 -0.032 4.530 -9.116 1.00 95.20 O ANISOU 181 OP1 DC C 10 14910 10870 10391 159 -619 -1352 O ATOM 182 OP2 DC C 10 -1.323 2.779 -7.694 1.00 83.23 O ANISOU 182 OP2 DC C 10 13733 9029 8863 -9 -946 -1150 O ATOM 183 O5' DC C 10 -2.421 4.843 -8.519 1.00 92.49 O ANISOU 183 O5' DC C 10 14583 10460 10099 -203 -591 -962 O ATOM 184 C5' DC C 10 -2.472 6.048 -9.264 1.00 72.62 C ANISOU 184 C5' DC C 10 11871 8113 7609 -226 -387 -949 C ATOM 185 C4' DC C 10 -3.642 6.805 -8.682 1.00 66.47 C ANISOU 185 C4' DC C 10 11005 7375 6875 -416 -287 -743 C ATOM 186 O4' DC C 10 -4.802 5.938 -8.746 1.00 70.11 O ANISOU 186 O4' DC C 10 11626 7713 7300 -556 -434 -609 O ATOM 187 C3' DC C 10 -3.487 7.190 -7.215 1.00 67.16 C ANISOU 187 C3' DC C 10 11028 7476 7014 -424 -246 -699 C ATOM 188 O3' DC C 10 -3.733 8.562 -7.165 1.00 69.24 O ANISOU 188 O3' DC C 10 11082 7891 7335 -482 -51 -635 O ATOM 189 C2' DC C 10 -4.570 6.403 -6.473 1.00 66.16 C ANISOU 189 C2' DC C 10 11043 7230 6863 -571 -387 -535 C ATOM 190 C1' DC C 10 -5.576 6.080 -7.585 1.00 61.83 C ANISOU 190 C1' DC C 10 10569 6650 6275 -690 -434 -450 C ATOM 191 N1 DC C 10 -6.384 4.819 -7.475 1.00 58.58 N ANISOU 191 N1 DC C 10 10367 6071 5819 -792 -641 -354 N ATOM 192 C2 DC C 10 -7.781 4.885 -7.646 1.00 57.02 C ANISOU 192 C2 DC C 10 10179 5878 5609 -988 -642 -174 C ATOM 193 O2 DC C 10 -8.321 5.967 -7.879 1.00 58.28 O ANISOU 193 O2 DC C 10 10180 6177 5785 -1066 -477 -105 O ATOM 194 N3 DC C 10 -8.528 3.758 -7.586 1.00 52.21 N ANISOU 194 N3 DC C 10 9754 5118 4966 -1092 -830 -81 N ATOM 195 C4 DC C 10 -7.929 2.597 -7.337 1.00 65.96 C ANISOU 195 C4 DC C 10 11672 6697 6691 -1005 -1023 -158 C ATOM 196 N4 DC C 10 -8.720 1.523 -7.258 1.00 67.79 N ANISOU 196 N4 DC C 10 12082 6774 6900 -1123 -1214 -49 N ATOM 197 C5 DC C 10 -6.509 2.503 -7.152 1.00 65.99 C ANISOU 197 C5 DC C 10 11677 6693 6702 -796 -1031 -349 C ATOM 198 C6 DC C 10 -5.775 3.622 -7.234 1.00 59.59 C ANISOU 198 C6 DC C 10 10677 6043 5921 -696 -834 -444 C ATOM 199 P DC C 11 -3.232 9.478 -5.960 0.57 67.63 P ANISOU 199 P DC C 11 10715 7774 7208 -435 62 -647 P ATOM 200 OP1 DC C 11 -2.720 10.654 -6.694 1.00 66.36 O ANISOU 200 OP1 DC C 11 10366 7751 7094 -389 238 -711 O ATOM 201 OP2 DC C 11 -2.424 8.743 -4.963 1.00 59.79 O ANISOU 201 OP2 DC C 11 9812 6694 6210 -314 -42 -741 O ATOM 202 O5' DC C 11 -4.596 9.836 -5.205 1.00 80.10 O ANISOU 202 O5' DC C 11 12257 9379 8798 -618 72 -438 O ATOM 203 C5' DC C 11 -5.683 10.301 -6.014 1.00 68.98 C ANISOU 203 C5' DC C 11 10810 8026 7373 -765 128 -319 C ATOM 204 C4' DC C 11 -6.985 10.060 -5.270 1.00 54.40 C ANISOU 204 C4' DC C 11 9008 6162 5497 -933 60 -135 C ATOM 205 O4' DC C 11 -7.383 8.668 -5.429 1.00 55.26 O ANISOU 205 O4' DC C 11 9340 6118 5540 -983 -122 -97 O ATOM 206 C3' DC C 11 -6.933 10.364 -3.791 1.00 51.21 C ANISOU 206 C3' DC C 11 8524 5805 5129 -923 67 -91 C ATOM 207 O3' DC C 11 -7.821 11.493 -3.596 1.00 46.56 O ANISOU 207 O3' DC C 11 7768 5359 4563 -1033 176 22 O ATOM 208 C2' DC C 11 -7.417 9.062 -3.125 1.00 53.84 C ANISOU 208 C2' DC C 11 9049 6010 5400 -990 -114 -3 C ATOM 209 C1' DC C 11 -8.017 8.228 -4.258 1.00 49.21 C ANISOU 209 C1' DC C 11 8624 5318 4754 -1076 -211 31 C ATOM 210 N1 DC C 11 -7.888 6.695 -4.178 1.00 57.94 N ANISOU 210 N1 DC C 11 9968 6234 5811 -1064 -419 20 N ATOM 211 C2 DC C 11 -9.067 5.941 -4.256 1.00 53.73 C ANISOU 211 C2 DC C 11 9564 5624 5228 -1237 -541 175 C ATOM 212 O2 DC C 11 -10.139 6.543 -4.371 1.00 57.67 O ANISOU 212 O2 DC C 11 9975 6221 5715 -1384 -468 304 O ATOM 213 N3 DC C 11 -9.020 4.584 -4.216 1.00 55.16 N ANISOU 213 N3 DC C 11 9960 5623 5374 -1240 -742 178 N ATOM 214 C4 DC C 11 -7.848 3.955 -4.068 1.00 61.15 C ANISOU 214 C4 DC C 11 10814 6280 6139 -1070 -828 25 C ATOM 215 N4 DC C 11 -7.874 2.600 -4.015 1.00 52.23 N ANISOU 215 N4 DC C 11 9907 4961 4976 -1081 -1047 35 N ATOM 216 C5 DC C 11 -6.622 4.703 -3.981 1.00 50.42 C ANISOU 216 C5 DC C 11 9325 5011 4821 -886 -700 -145 C ATOM 217 C6 DC C 11 -6.683 6.048 -4.049 1.00 53.46 C ANISOU 217 C6 DC C 11 9492 5571 5247 -894 -498 -137 C ATOM 218 P DT C 12 -8.163 12.217 -2.229 1.00 65.35 P ANISOU 218 P DT C 12 9998 7855 6977 -1055 213 99 P ATOM 219 OP1 DT C 12 -8.780 13.513 -2.592 1.00 66.73 O ANISOU 219 OP1 DT C 12 9996 8173 7184 -1125 338 149 O ATOM 220 OP2 DT C 12 -6.949 12.189 -1.382 1.00 70.98 O ANISOU 220 OP2 DT C 12 10673 8552 7745 -883 216 -25 O ATOM 221 O5' DT C 12 -9.341 11.348 -1.577 1.00 52.28 O ANISOU 221 O5' DT C 12 8460 6166 5239 -1211 81 271 O ATOM 222 C5' DT C 12 -10.407 11.072 -2.511 1.00 50.90 C ANISOU 222 C5' DT C 12 8368 5969 5003 -1366 51 368 C ATOM 223 C4' DT C 12 -11.356 10.012 -1.951 1.00 49.15 C ANISOU 223 C4' DT C 12 8289 5683 4702 -1509 -98 519 C ATOM 224 O4' DT C 12 -10.737 8.708 -2.046 1.00 59.81 O ANISOU 224 O4' DT C 12 9843 6847 6034 -1449 -237 464 O ATOM 225 C3' DT C 12 -11.708 10.222 -0.505 1.00 52.17 C ANISOU 225 C3' DT C 12 8580 6168 5073 -1540 -115 617 C ATOM 226 O3' DT C 12 -13.021 10.775 -0.528 1.00 49.84 O ANISOU 226 O3' DT C 12 8198 6008 4731 -1704 -83 753 O ATOM 227 C2' DT C 12 -11.591 8.827 0.164 1.00 59.73 C ANISOU 227 C2' DT C 12 9727 6981 5986 -1555 -283 668 C ATOM 228 C1' DT C 12 -11.234 7.890 -1.000 0.78 51.65 C ANISOU 228 C1' DT C 12 8901 5771 4954 -1534 -366 591 C ATOM 229 N1 DT C 12 -10.193 6.805 -0.873 0.76 53.96 N ANISOU 229 N1 DT C 12 9364 5884 5252 -1407 -489 486 N ATOM 230 C2 DT C 12 -10.601 5.488 -0.897 1.00 50.59 C ANISOU 230 C2 DT C 12 9152 5296 4775 -1495 -673 565 C ATOM 231 O2 DT C 12 -11.765 5.152 -0.980 1.00 53.44 O ANISOU 231 O2 DT C 12 9563 5653 5087 -1678 -734 724 O ATOM 232 N3 DT C 12 -9.596 4.562 -0.838 1.00 47.60 N ANISOU 232 N3 DT C 12 8929 4755 4403 -1361 -792 448 N ATOM 233 C4 DT C 12 -8.236 4.793 -0.744 1.00 63.20 C ANISOU 233 C4 DT C 12 10867 6724 6421 -1150 -742 256 C ATOM 234 O4 DT C 12 -7.402 3.879 -0.679 0.97 55.68 O ANISOU 234 O4 DT C 12 10070 5625 5462 -1034 -869 149 O ATOM 235 C5 DT C 12 -7.877 6.193 -0.730 0.66 62.30 C ANISOU 235 C5 DT C 12 10520 6789 6363 -1075 -539 186 C ATOM 236 C7 DT C 12 -6.432 6.578 -0.641 1.00 62.48 C ANISOU 236 C7 DT C 12 10475 6827 6439 -857 -466 -19 C ATOM 237 C6 DT C 12 -8.849 7.115 -0.800 1.00 56.97 C ANISOU 237 C6 DT C 12 9696 6261 5690 -1205 -429 304 C ATOM 238 P DG C 13 -13.803 11.163 0.807 1.00 51.50 P ANISOU 238 P DG C 13 8279 6389 4901 -1780 -95 886 P ATOM 239 OP1 DG C 13 -15.059 11.811 0.423 1.00 55.26 O ANISOU 239 OP1 DG C 13 8669 7002 5326 -1931 -51 983 O ATOM 240 OP2 DG C 13 -12.979 11.888 1.795 1.00 53.18 O ANISOU 240 OP2 DG C 13 8331 6696 5180 -1623 -33 806 O ATOM 241 O5' DG C 13 -14.189 9.740 1.461 1.00 58.75 O ANISOU 241 O5' DG C 13 9378 7201 5744 -1878 -263 1013 O ATOM 242 C5' DG C 13 -15.522 9.220 1.341 0.67 53.41 C ANISOU 242 C5' DG C 13 8774 6543 4977 -2089 -341 1183 C ATOM 243 C4' DG C 13 -15.735 7.966 2.210 1.00 51.23 C ANISOU 243 C4' DG C 13 8643 6180 4643 -2168 -501 1311 C ATOM 244 O4' DG C 13 -14.721 6.969 1.884 1.00 51.43 O ANISOU 244 O4' DG C 13 8861 5971 4708 -2063 -591 1212 O ATOM 245 C3' DG C 13 -15.624 8.137 3.693 1.00 54.70 C ANISOU 245 C3' DG C 13 8972 6748 5065 -2127 -512 1373 C ATOM 246 O3' DG C 13 -16.346 7.057 4.248 1.00 70.77 O ANISOU 246 O3' DG C 13 11134 8740 7018 -2284 -656 1551 O ATOM 247 C2' DG C 13 -14.145 7.862 3.921 1.00 54.50 C ANISOU 247 C2' DG C 13 9004 6587 5115 -1916 -518 1214 C ATOM 248 C1' DG C 13 -14.072 6.594 3.073 1.00 49.50 C ANISOU 248 C1' DG C 13 8626 5712 4469 -1973 -647 1215 C ATOM 249 N9 DG C 13 -12.700 6.076 2.887 1.00 57.14 N ANISOU 249 N9 DG C 13 9712 6503 5497 -1786 -685 1045 N ATOM 250 C8 DG C 13 -11.537 6.815 2.835 1.00 53.31 C ANISOU 250 C8 DG C 13 9121 6046 5087 -1581 -572 857 C ATOM 251 N7 DG C 13 -10.468 6.089 2.681 0.65 52.08 N ANISOU 251 N7 DG C 13 9106 5722 4958 -1445 -643 726 N ATOM 252 C5 DG C 13 -10.930 4.788 2.645 1.00 45.40 C ANISOU 252 C5 DG C 13 8478 4716 4056 -1559 -822 832 C ATOM 253 C6 DG C 13 -10.224 3.564 2.511 1.00 61.01 C ANISOU 253 C6 DG C 13 10680 6472 6030 -1487 -983 761 C ATOM 254 O6 DG C 13 -8.997 3.413 2.403 1.00 53.85 O ANISOU 254 O6 DG C 13 9819 5483 5160 -1294 -988 574 O ATOM 255 N1 DG C 13 -11.079 2.443 2.513 1.00 59.94 N ANISOU 255 N1 DG C 13 10726 6210 5839 -1661 -1158 924 N ATOM 256 C2 DG C 13 -12.452 2.515 2.632 1.00 59.65 C ANISOU 256 C2 DG C 13 10648 6264 5751 -1884 -1164 1131 C ATOM 257 N2 DG C 13 -13.134 1.352 2.627 1.00 64.49 N ANISOU 257 N2 DG C 13 11450 6732 6321 -2041 -1347 1276 N ATOM 258 N3 DG C 13 -13.118 3.659 2.758 1.00 55.74 N ANISOU 258 N3 DG C 13 9940 5991 5248 -1947 -1009 1190 N ATOM 259 C4 DG C 13 -12.303 4.754 2.766 1.00 54.95 C ANISOU 259 C4 DG C 13 9668 6005 5207 -1775 -848 1034 C ATOM 260 P DT C 14 -17.604 7.342 5.175 1.00 68.02 P ANISOU 260 P DT C 14 10649 8628 6569 -2448 -668 1746 P ATOM 261 OP1 DT C 14 -18.660 7.837 4.266 0.72 62.74 O ANISOU 261 OP1 DT C 14 9934 8044 5861 -2590 -616 1784 O ATOM 262 OP2 DT C 14 -17.231 8.149 6.373 1.00 61.54 O ANISOU 262 OP2 DT C 14 9623 8002 5756 -2320 -602 1722 O ATOM 263 O5' DT C 14 -17.907 5.832 5.626 1.00 77.92 O ANISOU 263 O5' DT C 14 12113 9733 7762 -2582 -850 1907 O ATOM 264 C5' DT C 14 -17.997 4.863 4.577 1.00 78.85 C ANISOU 264 C5' DT C 14 12455 9613 7893 -2664 -948 1907 C ATOM 265 C4' DT C 14 -17.663 3.464 5.051 1.00 75.88 C ANISOU 265 C4' DT C 14 12294 9031 7508 -2692 -1128 1983 C ATOM 266 O4' DT C 14 -16.265 3.148 4.812 1.00 70.17 O ANISOU 266 O4' DT C 14 11679 8116 6867 -2481 -1148 1795 O ATOM 267 C3' DT C 14 -17.944 3.207 6.529 1.00 76.31 C ANISOU 267 C3' DT C 14 12292 9211 7493 -2748 -1187 2149 C ATOM 268 O3' DT C 14 -18.458 1.907 6.593 1.00 79.26 O ANISOU 268 O3' DT C 14 12867 9425 7822 -2921 -1367 2313 O ATOM 269 C2' DT C 14 -16.567 3.276 7.164 1.00 70.60 C ANISOU 269 C2' DT C 14 11562 8429 6832 -2508 -1166 2002 C ATOM 270 C1' DT C 14 -15.706 2.698 6.042 1.00 66.59 C ANISOU 270 C1' DT C 14 11250 7649 6402 -2408 -1216 1834 C ATOM 271 N1 DT C 14 -14.306 3.184 6.085 1.00 65.72 N ANISOU 271 N1 DT C 14 11093 7506 6372 -2147 -1132 1608 N ATOM 272 C2 DT C 14 -13.286 2.285 5.885 1.00 62.18 C ANISOU 272 C2 DT C 14 10841 6821 5963 -2024 -1240 1492 C ATOM 273 O2 DT C 14 -13.467 1.108 5.676 1.00 65.55 O ANISOU 273 O2 DT C 14 11484 7054 6368 -2114 -1412 1564 O ATOM 274 N3 DT C 14 -12.030 2.826 5.928 1.00 64.85 N ANISOU 274 N3 DT C 14 11113 7159 6368 -1786 -1147 1279 N ATOM 275 C4 DT C 14 -11.702 4.154 6.158 1.00 61.72 C ANISOU 275 C4 DT C 14 10477 6961 6015 -1668 -964 1182 C ATOM 276 O4 DT C 14 -10.532 4.532 6.200 1.00 64.70 O ANISOU 276 O4 DT C 14 10809 7318 6455 -1459 -896 992 O ATOM 277 C5 DT C 14 -12.818 5.047 6.385 1.00 56.22 C ANISOU 277 C5 DT C 14 9585 6496 5280 -1803 -870 1315 C ATOM 278 C7 DT C 14 -12.572 6.508 6.664 1.00 51.29 C ANISOU 278 C7 DT C 14 8696 6087 4704 -1685 -693 1221 C ATOM 279 C6 DT C 14 -14.057 4.529 6.329 1.00 57.66 C ANISOU 279 C6 DT C 14 9830 6693 5385 -2031 -955 1516 C ATOM 280 P DT C 15 -19.027 1.208 7.911 1.00 80.21 P ANISOU 280 P DT C 15 13003 9621 7853 -3064 -1485 2552 P ATOM 281 OP1 DT C 15 -20.184 0.468 7.353 1.00 83.38 O ANISOU 281 OP1 DT C 15 13522 9954 8204 -3322 -1596 2722 O ATOM 282 OP2 DT C 15 -19.157 2.072 9.120 1.00 67.89 O ANISOU 282 OP2 DT C 15 11201 8358 6237 -3013 -1386 2604 O ATOM 283 O5' DT C 15 -17.838 0.192 8.227 1.00 69.78 O ANISOU 283 O5' DT C 15 11892 8036 6587 -2926 -1617 2482 O ATOM 284 C5' DT C 15 -17.509 -0.802 7.259 1.00 72.54 C ANISOU 284 C5' DT C 15 12491 8079 6990 -2935 -1754 2418 C ATOM 285 C4' DT C 15 -16.399 -1.693 7.797 1.00 72.40 C ANISOU 285 C4' DT C 15 12650 7852 7006 -2793 -1885 2356 C ATOM 286 O4' DT C 15 -15.112 -1.023 7.670 1.00 61.69 O ANISOU 286 O4' DT C 15 11227 6493 5720 -2517 -1768 2099 O ATOM 287 C3' DT C 15 -16.517 -2.132 9.258 1.00 69.89 C ANISOU 287 C3' DT C 15 12325 7608 6623 -2844 -1962 2537 C ATOM 288 O3' DT C 15 -16.107 -3.469 9.259 1.00 81.95 O ANISOU 288 O3' DT C 15 14123 8847 8168 -2859 -2176 2565 O ATOM 289 C2' DT C 15 -15.506 -1.240 9.972 1.00 66.64 C ANISOU 289 C2' DT C 15 11745 7336 6238 -2591 -1816 2374 C ATOM 290 C1' DT C 15 -14.428 -1.104 8.894 1.00 72.96 C ANISOU 290 C1' DT C 15 12628 7960 7135 -2393 -1780 2098 C ATOM 291 N1 DT C 15 -13.634 0.136 9.020 1.00 66.79 N ANISOU 291 N1 DT C 15 11637 7339 6402 -2172 -1583 1902 N ATOM 292 C2 DT C 15 -12.270 0.087 8.844 1.00 57.79 C ANISOU 292 C2 DT C 15 10563 6064 5331 -1933 -1573 1669 C ATOM 293 O2 DT C 15 -11.648 -0.930 8.575 1.00 63.98 O ANISOU 293 O2 DT C 15 11573 6604 6131 -1878 -1723 1602 O ATOM 294 N3 DT C 15 -11.654 1.292 8.995 1.00 58.67 N ANISOU 294 N3 DT C 15 10460 6343 5490 -1755 -1388 1511 N ATOM 295 C4 DT C 15 -12.234 2.504 9.299 0.59 58.61 C ANISOU 295 C4 DT C 15 10191 6605 5473 -1782 -1229 1555 C ATOM 296 O4 DT C 15 -11.565 3.520 9.409 1.00 55.96 O ANISOU 296 O4 DT C 15 9682 6385 5195 -1608 -1084 1398 O ATOM 297 C5 DT C 15 -13.662 2.481 9.479 1.00 59.39 C ANISOU 297 C5 DT C 15 10237 6839 5490 -2027 -1255 1792 C ATOM 298 C7 DT C 15 -14.418 3.731 9.820 1.00 56.68 C ANISOU 298 C7 DT C 15 9617 6799 5118 -2070 -1109 1849 C ATOM 299 C6 DT C 15 -14.290 1.311 9.322 1.00 58.77 C ANISOU 299 C6 DT C 15 10361 6608 5361 -2212 -1423 1954 C ATOM 300 P DC C 16 -16.131 -4.446 10.520 1.00 79.08 P ANISOU 300 P DC C 16 13874 8425 7749 -2933 -2341 2762 P ATOM 301 OP1 DC C 16 -16.612 -5.741 9.986 1.00 89.82 O ANISOU 301 OP1 DC C 16 15493 9519 9116 -3118 -2571 2887 O ATOM 302 OP2 DC C 16 -16.789 -3.800 11.689 1.00 68.20 O ANISOU 302 OP2 DC C 16 12267 7365 6283 -3009 -2238 2938 O ATOM 303 O5' DC C 16 -14.569 -4.595 10.805 1.00 81.84 O ANISOU 303 O5' DC C 16 14311 8630 8156 -2638 -2357 2530 O ATOM 304 C5' DC C 16 -13.790 -5.160 9.774 1.00 78.04 C ANISOU 304 C5' DC C 16 14030 7874 7748 -2523 -2454 2332 C ATOM 305 C4' DC C 16 -12.318 -5.115 10.124 1.00 77.55 C ANISOU 305 C4' DC C 16 14006 7735 7726 -2232 -2437 2098 C ATOM 306 O4' DC C 16 -11.852 -3.747 10.206 1.00 67.90 O ANISOU 306 O4' DC C 16 12527 6743 6529 -2060 -2193 1937 O ATOM 307 C3' DC C 16 -11.951 -5.756 11.454 1.00 72.99 C ANISOU 307 C3' DC C 16 13507 7121 7105 -2194 -2546 2196 C ATOM 308 O3' DC C 16 -10.808 -6.538 11.219 1.00 81.68 O ANISOU 308 O3' DC C 16 14829 7958 8246 -2012 -2687 2006 O ATOM 309 C2' DC C 16 -11.608 -4.577 12.354 1.00 67.00 C ANISOU 309 C2' DC C 16 12477 6646 6333 -2043 -2330 2137 C ATOM 310 C1' DC C 16 -11.013 -3.621 11.322 1.00 65.40 C ANISOU 310 C1' DC C 16 12163 6483 6205 -1880 -2163 1875 C ATOM 311 N1 DC C 16 -11.171 -2.229 11.677 1.00 59.87 N ANISOU 311 N1 DC C 16 11159 6082 5506 -1822 -1933 1846 N ATOM 312 C2 DC C 16 -10.061 -1.401 11.875 1.00 58.12 C ANISOU 312 C2 DC C 16 10805 5938 5340 -1559 -1789 1610 C ATOM 313 O2 DC C 16 -8.921 -1.866 11.755 0.83 57.77 O ANISOU 313 O2 DC C 16 10902 5715 5334 -1373 -1851 1421 O ATOM 314 N3 DC C 16 -10.286 -0.103 12.190 1.00 56.91 N ANISOU 314 N3 DC C 16 10368 6057 5197 -1517 -1594 1594 N ATOM 315 C4 DC C 16 -11.541 0.365 12.316 1.00 61.75 C ANISOU 315 C4 DC C 16 10835 6871 5758 -1715 -1542 1791 C ATOM 316 N4 DC C 16 -11.716 1.659 12.635 0.80 59.24 N ANISOU 316 N4 DC C 16 10238 6818 5450 -1653 -1366 1756 N ATOM 317 C5 DC C 16 -12.677 -0.474 12.128 1.00 60.95 C ANISOU 317 C5 DC C 16 10864 6707 5589 -1983 -1679 2028 C ATOM 318 C6 DC C 16 -12.446 -1.753 11.800 1.00 62.68 C ANISOU 318 C6 DC C 16 11361 6644 5809 -2031 -1870 2050 C ATOM 319 P DT C 17 -10.243 -7.511 12.343 1.00 87.85 P ANISOU 319 P DT C 17 15786 8600 8993 -1950 -2862 2065 P ATOM 320 OP1 DT C 17 -9.484 -8.576 11.656 1.00 92.11 O ANISOU 320 OP1 DT C 17 16614 8811 9571 -1856 -3078 1910 O ATOM 321 OP2 DT C 17 -11.362 -7.810 13.271 1.00 90.16 O ANISOU 321 OP2 DT C 17 16043 9003 9212 -2195 -2915 2399 O ATOM 322 O5' DT C 17 -9.163 -6.633 13.110 1.00 90.82 O ANISOU 322 O5' DT C 17 15991 9138 9378 -1669 -2684 1868 O ATOM 323 C5' DT C 17 -8.028 -6.317 12.354 1.00 84.13 C ANISOU 323 C5' DT C 17 15160 8211 8593 -1429 -2625 1552 C ATOM 324 C4' DT C 17 -6.974 -5.645 13.198 1.00 77.91 C ANISOU 324 C4' DT C 17 14236 7550 7815 -1167 -2487 1375 C ATOM 325 O4' DT C 17 -7.356 -4.279 13.489 0.90 67.08 O ANISOU 325 O4' DT C 17 12548 6488 6454 -1164 -2241 1398 O ATOM 326 C3' DT C 17 -6.667 -6.303 14.531 1.00 75.39 C ANISOU 326 C3' DT C 17 14008 7191 7444 -1114 -2596 1466 C ATOM 327 O3' DT C 17 -5.260 -6.299 14.582 1.00 78.65 O ANISOU 327 O3' DT C 17 14477 7516 7890 -824 -2587 1174 O ATOM 328 C2' DT C 17 -7.306 -5.364 15.561 1.00 75.22 C ANISOU 328 C2' DT C 17 13704 7489 7387 -1165 -2421 1628 C ATOM 329 C1' DT C 17 -7.163 -4.012 14.867 1.00 70.36 C ANISOU 329 C1' DT C 17 12843 7057 6834 -1075 -2187 1456 C ATOM 330 N1 DT C 17 -8.175 -2.946 15.151 1.00 63.02 N ANISOU 330 N1 DT C 17 11630 6430 5884 -1202 -2017 1611 N ATOM 331 C2 DT C 17 -7.741 -1.667 15.385 1.00 59.31 C ANISOU 331 C2 DT C 17 10898 6178 5459 -1030 -1807 1460 C ATOM 332 O2 DT C 17 -6.561 -1.368 15.417 1.00 61.28 O ANISOU 332 O2 DT C 17 11130 6389 5764 -783 -1745 1214 O ATOM 333 N3 DT C 17 -8.741 -0.752 15.601 1.00 50.50 N ANISOU 333 N3 DT C 17 9537 5331 4318 -1155 -1681 1605 N ATOM 334 C4 DT C 17 -10.099 -0.972 15.601 0.45 56.00 C ANISOU 334 C4 DT C 17 10220 6113 4944 -1429 -1732 1874 C ATOM 335 O4 DT C 17 -10.894 -0.052 15.794 1.00 57.13 O ANISOU 335 O4 DT C 17 10127 6517 5062 -1508 -1610 1965 O ATOM 336 C5 DT C 17 -10.484 -2.343 15.348 1.00 58.43 C ANISOU 336 C5 DT C 17 10808 6182 5211 -1608 -1946 2027 C ATOM 337 C7 DT C 17 -11.920 -2.760 15.316 1.00 63.08 C ANISOU 337 C7 DT C 17 11417 6828 5724 -1920 -2028 2324 C ATOM 338 C6 DT C 17 -9.522 -3.239 15.120 1.00 61.10 C ANISOU 338 C6 DT C 17 11390 6244 5581 -1487 -2079 1889 C ATOM 339 P DG C 18 -4.406 -6.890 15.786 1.00 88.40 P ANISOU 339 P DG C 18 15823 8677 9088 -647 -2682 1125 P ATOM 340 OP1 DG C 18 -3.194 -7.524 15.236 1.00 95.66 O ANISOU 340 OP1 DG C 18 16958 9357 10031 -440 -2805 846 O ATOM 341 OP2 DG C 18 -5.314 -7.646 16.680 1.00 92.41 O ANISOU 341 OP2 DG C 18 16416 9170 9525 -857 -2822 1448 O ATOM 342 O5' DG C 18 -3.934 -5.560 16.501 1.00 83.19 O ANISOU 342 O5' DG C 18 14855 8301 8452 -456 -2423 1005 O ATOM 343 C5' DG C 18 -3.078 -4.666 15.811 1.00 82.42 C ANISOU 343 C5' DG C 18 14628 8263 8425 -259 -2259 717 C ATOM 344 C4' DG C 18 -2.585 -3.633 16.800 1.00 78.33 C ANISOU 344 C4' DG C 18 13854 7981 7928 -69 -2066 628 C ATOM 345 O4' DG C 18 -3.652 -2.696 17.045 0.85 66.81 O ANISOU 345 O4' DG C 18 12135 6783 6467 -221 -1919 819 O ATOM 346 C3' DG C 18 -2.200 -4.168 18.185 1.00 77.85 C ANISOU 346 C3' DG C 18 13855 7912 7814 43 -2145 673 C ATOM 347 O3' DG C 18 -1.075 -3.442 18.651 1.00 81.95 O ANISOU 347 O3' DG C 18 14231 8528 8378 334 -2004 416 O ATOM 348 C2' DG C 18 -3.421 -3.865 19.058 1.00 72.43 C ANISOU 348 C2' DG C 18 13000 7447 7075 -147 -2101 986 C ATOM 349 C1' DG C 18 -3.823 -2.520 18.455 1.00 69.51 C ANISOU 349 C1' DG C 18 12349 7296 6763 -178 -1887 943 C ATOM 350 N9 DG C 18 -5.232 -2.178 18.557 1.00 60.66 N ANISOU 350 N9 DG C 18 11087 6360 5600 -432 -1851 1222 N ATOM 351 C8 DG C 18 -6.298 -3.038 18.381 1.00 56.95 C ANISOU 351 C8 DG C 18 10768 5807 5064 -710 -2002 1490 C ATOM 352 N7 DG C 18 -7.450 -2.441 18.476 1.00 65.26 N ANISOU 352 N7 DG C 18 11630 7083 6083 -896 -1922 1689 N ATOM 353 C5 DG C 18 -7.123 -1.097 18.701 1.00 66.86 C ANISOU 353 C5 DG C 18 11544 7522 6337 -726 -1713 1539 C ATOM 354 C6 DG C 18 -7.951 0.040 18.881 1.00 57.78 C ANISOU 354 C6 DG C 18 10101 6673 5179 -796 -1563 1628 C ATOM 355 O6 DG C 18 -9.186 0.079 18.879 1.00 57.80 O ANISOU 355 O6 DG C 18 10038 6809 5116 -1031 -1578 1862 O ATOM 356 N1 DG C 18 -7.214 1.215 19.070 1.00 52.64 N ANISOU 356 N1 DG C 18 9222 6172 4606 -559 -1391 1407 N ATOM 357 C2 DG C 18 -5.843 1.274 19.084 1.00 53.49 C ANISOU 357 C2 DG C 18 9376 6161 4788 -295 -1358 1137 C ATOM 358 N2 DG C 18 -5.289 2.472 19.298 1.00 53.15 N ANISOU 358 N2 DG C 18 9086 6286 4822 -97 -1191 956 N ATOM 359 N3 DG C 18 -5.057 0.217 18.922 1.00 67.30 N ANISOU 359 N3 DG C 18 11395 7644 6534 -224 -1490 1046 N ATOM 360 C4 DG C 18 -5.761 -0.926 18.739 1.00 63.90 C ANISOU 360 C4 DG C 18 11191 7057 6029 -446 -1667 1256 C TER 361 DG C 18 ATOM 362 O5' DC D 1 -15.128 6.849 22.758 1.00 67.67 O ANISOU 362 O5' DC D 1 10221 10295 5198 558 695 1611 O ATOM 363 C5' DC D 1 -14.696 7.694 23.826 1.00 62.70 C ANISOU 363 C5' DC D 1 9415 9859 4549 894 690 1514 C ATOM 364 C4' DC D 1 -13.279 8.114 23.511 0.59 59.89 C ANISOU 364 C4' DC D 1 9100 9302 4353 1152 652 1245 C ATOM 365 O4' DC D 1 -12.488 6.913 23.596 1.00 54.16 O ANISOU 365 O4' DC D 1 8688 8282 3609 1164 631 1251 O ATOM 366 C3' DC D 1 -13.041 8.675 22.107 1.00 51.13 C ANISOU 366 C3' DC D 1 7940 8074 3411 1053 643 1091 C ATOM 367 O3' DC D 1 -12.150 9.763 22.215 0.48 57.76 O ANISOU 367 O3' DC D 1 8620 8947 4379 1350 617 863 O ATOM 368 C2' DC D 1 -12.397 7.526 21.339 1.00 53.77 C ANISOU 368 C2' DC D 1 8585 8058 3787 928 621 1074 C ATOM 369 C1' DC D 1 -11.684 6.768 22.473 0.95 55.39 C ANISOU 369 C1' DC D 1 8974 8168 3905 1129 602 1091 C ATOM 370 N1 DC D 1 -11.586 5.312 22.306 1.00 55.02 N ANISOU 370 N1 DC D 1 9246 7866 3794 958 580 1207 N ATOM 371 C2 DC D 1 -10.330 4.704 22.378 0.78 67.05 C ANISOU 371 C2 DC D 1 11000 9124 5351 1130 534 1070 C ATOM 372 O2 DC D 1 -9.346 5.423 22.597 1.00 74.83 O ANISOU 372 O2 DC D 1 11908 10105 6421 1420 523 858 O ATOM 373 N3 DC D 1 -10.237 3.353 22.230 1.00 69.26 N ANISOU 373 N3 DC D 1 11580 9165 5571 977 496 1171 N ATOM 374 C4 DC D 1 -11.342 2.634 22.003 0.74 73.36 C ANISOU 374 C4 DC D 1 12163 9697 6013 660 504 1403 C ATOM 375 N4 DC D 1 -11.219 1.312 21.841 1.00 73.80 N ANISOU 375 N4 DC D 1 12514 9502 6024 514 451 1496 N ATOM 376 C5 DC D 1 -12.629 3.248 21.919 0.68 73.07 C ANISOU 376 C5 DC D 1 11887 9931 5943 478 559 1546 C ATOM 377 C6 DC D 1 -12.707 4.577 22.074 1.00 64.16 C ANISOU 377 C6 DC D 1 10470 9045 4863 636 595 1438 C ATOM 378 P DC D 2 -11.803 10.640 20.911 1.00 70.33 P ANISOU 378 P DC D 2 10095 10468 6159 1318 606 685 P ATOM 379 OP1 DC D 2 -11.288 11.901 21.489 1.00 60.70 O ANISOU 379 OP1 DC D 2 8635 9404 5026 1631 577 518 O ATOM 380 OP2 DC D 2 -12.889 10.509 19.896 1.00 57.29 O ANISOU 380 OP2 DC D 2 8421 8853 4492 973 636 807 O ATOM 381 O5' DC D 2 -10.567 9.885 20.246 1.00 55.70 O ANISOU 381 O5' DC D 2 8503 8263 4396 1355 579 557 O ATOM 382 C5' DC D 2 -9.280 10.048 20.829 1.00 55.10 C ANISOU 382 C5' DC D 2 8469 8083 4381 1678 547 380 C ATOM 383 C4' DC D 2 -8.406 9.129 20.001 0.76 54.62 C ANISOU 383 C4' DC D 2 8682 7702 4371 1617 522 305 C ATOM 384 O4' DC D 2 -8.940 7.800 20.183 1.00 53.64 O ANISOU 384 O4' DC D 2 8798 7481 4103 1412 526 497 O ATOM 385 C3' DC D 2 -8.400 9.374 18.488 1.00 48.28 C ANISOU 385 C3' DC D 2 7854 6800 3691 1438 521 240 C ATOM 386 O3' DC D 2 -7.055 9.532 18.091 1.00 54.98 O ANISOU 386 O3' DC D 2 8763 7467 4662 1632 486 28 O ATOM 387 C2' DC D 2 -8.903 8.073 17.854 1.00 50.57 C ANISOU 387 C2' DC D 2 8391 6923 3899 1142 517 388 C ATOM 388 C1' DC D 2 -8.610 7.104 19.031 1.00 48.59 C ANISOU 388 C1' DC D 2 8349 6597 3516 1247 499 462 C ATOM 389 N1 DC D 2 -9.322 5.810 18.944 1.00 56.86 N ANISOU 389 N1 DC D 2 9619 7540 4445 980 491 665 N ATOM 390 C2 DC D 2 -8.542 4.662 19.033 1.00 58.15 C ANISOU 390 C2 DC D 2 10083 7443 4570 1016 437 642 C ATOM 391 O2 DC D 2 -7.328 4.827 19.219 1.00 58.11 O ANISOU 391 O2 DC D 2 10131 7328 4619 1275 409 450 O ATOM 392 N3 DC D 2 -9.145 3.446 18.929 0.57 59.12 N ANISOU 392 N3 DC D 2 10419 7446 4598 772 413 825 N ATOM 393 C4 DC D 2 -10.473 3.381 18.740 1.00 64.98 C ANISOU 393 C4 DC D 2 11073 8327 5290 500 448 1025 C ATOM 394 N4 DC D 2 -11.061 2.183 18.610 1.00 62.20 N ANISOU 394 N4 DC D 2 10927 7847 4861 253 417 1206 N ATOM 395 C5 DC D 2 -11.278 4.558 18.638 0.85 60.13 C ANISOU 395 C5 DC D 2 10152 7990 4706 462 511 1043 C ATOM 396 C6 DC D 2 -10.668 5.738 18.750 1.00 57.97 C ANISOU 396 C6 DC D 2 9677 7826 4522 707 526 861 C ATOM 397 P DA D 3 -6.651 10.159 16.665 1.00 48.63 P ANISOU 397 P DA D 3 7866 6589 4022 1576 480 -105 P ATOM 398 OP1 DA D 3 -6.127 11.472 17.016 1.00 44.19 O ANISOU 398 OP1 DA D 3 7054 6153 3582 1828 475 -256 O ATOM 399 OP2 DA D 3 -7.714 10.000 15.611 1.00 44.23 O ANISOU 399 OP2 DA D 3 7286 6064 3455 1252 506 22 O ATOM 400 O5' DA D 3 -5.421 9.217 16.242 1.00 54.21 O ANISOU 400 O5' DA D 3 8849 7003 4746 1649 433 -224 O ATOM 401 C5' DA D 3 -4.368 9.073 17.186 1.00 56.54 C ANISOU 401 C5' DA D 3 9234 7220 5028 1935 405 -345 C ATOM 402 C4' DA D 3 -3.575 7.841 16.841 1.00 49.45 C ANISOU 402 C4' DA D 3 8653 6053 4083 1923 356 -393 C ATOM 403 O4' DA D 3 -4.391 6.694 17.182 1.00 52.47 O ANISOU 403 O4' DA D 3 9232 6393 4311 1723 353 -194 O ATOM 404 C3' DA D 3 -3.228 7.714 15.364 1.00 55.24 C ANISOU 404 C3' DA D 3 9434 6652 4904 1796 331 -468 C ATOM 405 O3' DA D 3 -1.874 7.419 15.149 1.00 61.37 O ANISOU 405 O3' DA D 3 10353 7244 5721 1982 280 -655 O ATOM 406 C2' DA D 3 -4.022 6.525 14.835 1.00 60.66 C ANISOU 406 C2' DA D 3 10327 7234 5488 1502 311 -302 C ATOM 407 C1' DA D 3 -4.410 5.785 16.111 1.00 49.01 C ANISOU 407 C1' DA D 3 8990 5767 3863 1515 312 -167 C ATOM 408 N9 DA D 3 -5.781 5.337 15.958 1.00 65.21 N ANISOU 408 N9 DA D 3 11048 7893 5837 1216 335 59 N ATOM 409 C8 DA D 3 -6.903 6.118 15.851 1.00 64.46 C ANISOU 409 C8 DA D 3 10712 8024 5756 1074 395 170 C ATOM 410 N7 DA D 3 -8.008 5.437 15.680 1.00 59.24 N ANISOU 410 N7 DA D 3 10121 7377 5011 800 404 367 N ATOM 411 C5 DA D 3 -7.566 4.119 15.685 1.00 65.84 C ANISOU 411 C5 DA D 3 11265 7971 5780 761 338 390 C ATOM 412 C6 DA D 3 -8.243 2.896 15.568 1.00 63.10 C ANISOU 412 C6 DA D 3 11127 7506 5341 517 302 566 C ATOM 413 N6 DA D 3 -9.570 2.830 15.429 1.00 57.06 N ANISOU 413 N6 DA D 3 10280 6867 4534 256 340 760 N ATOM 414 N1 DA D 3 -7.499 1.759 15.601 1.00 63.62 N ANISOU 414 N1 DA D 3 11488 7320 5365 554 219 530 N ATOM 415 C2 DA D 3 -6.173 1.829 15.757 0.82 50.76 C ANISOU 415 C2 DA D 3 9942 5575 3769 819 181 328 C ATOM 416 N3 DA D 3 -5.425 2.920 15.882 1.00 67.71 N ANISOU 416 N3 DA D 3 11907 7817 6001 1063 217 150 N ATOM 417 C4 DA D 3 -6.193 4.033 15.837 1.00 73.13 C ANISOU 417 C4 DA D 3 12301 8744 6739 1016 293 197 C ATOM 418 P DG D 4 -1.292 7.584 13.667 1.00 65.54 P ANISOU 418 P DG D 4 10865 7675 6361 1930 254 -774 P ATOM 419 OP1 DG D 4 0.167 7.745 13.844 1.00 78.04 O ANISOU 419 OP1 DG D 4 12495 9154 8002 2211 218 -989 O ATOM 420 OP2 DG D 4 -2.135 8.501 12.870 1.00 48.90 O ANISOU 420 OP2 DG D 4 8505 5729 4345 1767 304 -708 O ATOM 421 O5' DG D 4 -1.426 6.172 13.023 1.00 57.64 O ANISOU 421 O5' DG D 4 10157 6482 5260 1737 195 -705 O ATOM 422 C5' DG D 4 -0.596 5.193 13.595 1.00 66.29 C ANISOU 422 C5' DG D 4 11523 7399 6265 1870 131 -775 C ATOM 423 C4' DG D 4 -0.998 3.913 12.907 1.00 63.04 C ANISOU 423 C4' DG D 4 11358 6826 5768 1640 65 -677 C ATOM 424 O4' DG D 4 -2.379 3.681 13.261 1.00 60.76 O ANISOU 424 O4' DG D 4 11041 6633 5411 1411 105 -448 O ATOM 425 C3' DG D 4 -0.928 3.943 11.388 1.00 70.54 C ANISOU 425 C3' DG D 4 12276 7730 6795 1516 36 -729 C ATOM 426 O3' DG D 4 -0.346 2.724 11.012 1.00 79.14 O ANISOU 426 O3' DG D 4 13657 8602 7811 1507 -70 -783 O ATOM 427 C2' DG D 4 -2.383 3.958 10.956 1.00 67.95 C ANISOU 427 C2' DG D 4 11853 7505 6460 1223 78 -529 C ATOM 428 C1' DG D 4 -3.026 3.211 12.121 1.00 58.52 C ANISOU 428 C1' DG D 4 10802 6296 5137 1157 78 -367 C ATOM 429 N9 DG D 4 -4.447 3.506 12.194 1.00 65.40 N ANISOU 429 N9 DG D 4 11523 7333 5992 932 145 -170 N ATOM 430 C8 DG D 4 -5.029 4.753 12.213 1.00 58.08 C ANISOU 430 C8 DG D 4 10296 6635 5136 925 232 -146 C ATOM 431 N7 DG D 4 -6.331 4.696 12.252 0.72 64.09 N ANISOU 431 N7 DG D 4 10991 7512 5851 695 273 41 N ATOM 432 C5 DG D 4 -6.628 3.334 12.246 1.00 63.78 C ANISOU 432 C5 DG D 4 11217 7303 5714 535 211 155 C ATOM 433 C6 DG D 4 -7.869 2.658 12.267 1.00 57.10 C ANISOU 433 C6 DG D 4 10430 6474 4791 261 215 369 C ATOM 434 O6 DG D 4 -9.006 3.133 12.302 1.00 57.11 O ANISOU 434 O6 DG D 4 10258 6660 4782 99 282 503 O ATOM 435 N1 DG D 4 -7.727 1.277 12.235 1.00 60.28 N ANISOU 435 N1 DG D 4 11130 6650 5124 172 123 425 N ATOM 436 C2 DG D 4 -6.536 0.613 12.206 0.87 63.12 C ANISOU 436 C2 DG D 4 11711 6797 5474 334 34 285 C ATOM 437 N2 DG D 4 -6.631 -0.721 12.184 1.00 62.55 N ANISOU 437 N2 DG D 4 11914 6523 5331 210 -62 369 N ATOM 438 N3 DG D 4 -5.357 1.221 12.187 1.00 61.88 N ANISOU 438 N3 DG D 4 11506 6630 5377 595 33 76 N ATOM 439 C4 DG D 4 -5.477 2.579 12.201 1.00 66.24 C ANISOU 439 C4 DG D 4 11762 7396 6011 678 126 26 C ATOM 440 P DA D 5 0.009 2.321 9.508 1.00 84.76 P ANISOU 440 P DA D 5 14437 9206 8561 1427 -146 -866 P ATOM 441 OP1 DA D 5 1.432 1.907 9.572 1.00 77.57 O ANISOU 441 OP1 DA D 5 13699 8152 7623 1661 -228 -1067 O ATOM 442 OP2 DA D 5 -0.464 3.297 8.487 1.00 75.02 O ANISOU 442 OP2 DA D 5 12935 8122 7445 1326 -81 -852 O ATOM 443 O5' DA D 5 -0.936 1.046 9.342 1.00 75.81 O ANISOU 443 O5' DA D 5 13522 7952 7329 1168 -214 -692 O ATOM 444 C5' DA D 5 -1.125 0.156 10.434 1.00 68.59 C ANISOU 444 C5' DA D 5 12821 6942 6298 1156 -249 -595 C ATOM 445 C4' DA D 5 -1.992 -0.981 9.930 1.00 71.45 C ANISOU 445 C4' DA D 5 13362 7182 6603 888 -327 -441 C ATOM 446 O4' DA D 5 -3.374 -0.577 10.052 1.00 71.53 O ANISOU 446 O4' DA D 5 13199 7350 6628 669 -235 -239 O ATOM 447 C3' DA D 5 -1.821 -1.397 8.469 1.00 69.59 C ANISOU 447 C3' DA D 5 13183 6847 6411 802 -418 -517 C ATOM 448 O3' DA D 5 -2.081 -2.779 8.390 1.00 78.09 O ANISOU 448 O3' DA D 5 14539 7725 7406 666 -545 -438 O ATOM 449 C2' DA D 5 -2.923 -0.630 7.749 1.00 67.27 C ANISOU 449 C2' DA D 5 12633 6724 6200 607 -326 -407 C ATOM 450 C1' DA D 5 -4.026 -0.661 8.802 1.00 66.38 C ANISOU 450 C1' DA D 5 12491 6699 6032 465 -254 -195 C ATOM 451 N9 DA D 5 -4.909 0.497 8.807 1.00 61.11 N ANISOU 451 N9 DA D 5 11524 6269 5426 381 -122 -111 N ATOM 452 C8 DA D 5 -4.523 1.810 8.821 1.00 62.39 C ANISOU 452 C8 DA D 5 11434 6600 5673 539 -34 -216 C ATOM 453 N7 DA D 5 -5.525 2.653 8.845 1.00 61.19 N ANISOU 453 N7 DA D 5 11047 6647 5557 420 64 -110 N ATOM 454 C5 DA D 5 -6.651 1.845 8.847 1.00 59.49 C ANISOU 454 C5 DA D 5 10931 6400 5273 164 48 79 C ATOM 455 C6 DA D 5 -8.031 2.138 8.883 0.73 61.14 C ANISOU 455 C6 DA D 5 10995 6767 5468 -58 121 255 C ATOM 456 N6 DA D 5 -8.551 3.379 8.906 1.00 56.32 N ANISOU 456 N6 DA D 5 10101 6387 4910 -58 223 266 N ATOM 457 N1 DA D 5 -8.868 1.085 8.894 1.00 61.38 N ANISOU 457 N1 DA D 5 11187 6706 5428 -285 76 420 N ATOM 458 C2 DA D 5 -8.379 -0.160 8.884 1.00 60.00 C ANISOU 458 C2 DA D 5 11298 6294 5204 -289 -40 414 C ATOM 459 N3 DA D 5 -7.106 -0.552 8.862 1.00 63.73 N ANISOU 459 N3 DA D 5 11935 6604 5675 -87 -123 251 N ATOM 460 C4 DA D 5 -6.286 0.509 8.843 1.00 56.70 C ANISOU 460 C4 DA D 5 10878 5816 4851 136 -68 86 C ATOM 461 P DA D 6 -1.871 -3.637 7.055 1.00 91.76 P ANISOU 461 P DA D 6 16421 9296 9148 588 -694 -511 P ATOM 462 OP1 DA D 6 -0.769 -4.577 7.350 1.00 94.11 O ANISOU 462 OP1 DA D 6 17005 9393 9361 755 -834 -645 O ATOM 463 OP2 DA D 6 -1.818 -2.750 5.870 1.00 86.14 O ANISOU 463 OP2 DA D 6 15474 8714 8540 595 -644 -599 O ATOM 464 O5' DA D 6 -3.247 -4.440 6.977 1.00 80.86 O ANISOU 464 O5' DA D 6 15121 7858 7745 280 -727 -280 O ATOM 465 C5' DA D 6 -4.396 -3.729 7.363 1.00 81.86 C ANISOU 465 C5' DA D 6 15033 8169 7899 125 -585 -105 C ATOM 466 C4' DA D 6 -5.647 -4.441 6.921 1.00 84.85 C ANISOU 466 C4' DA D 6 15463 8497 8279 -173 -626 82 C ATOM 467 O4' DA D 6 -6.727 -3.478 6.905 1.00 89.63 O ANISOU 467 O4' DA D 6 15794 9328 8932 -314 -477 205 O ATOM 468 C3' DA D 6 -5.597 -5.009 5.518 1.00 87.11 C ANISOU 468 C3' DA D 6 15821 8662 8613 -249 -748 6 C ATOM 469 O3' DA D 6 -6.444 -6.140 5.513 1.00 92.05 O ANISOU 469 O3' DA D 6 16625 9142 9209 -477 -845 169 O ATOM 470 C2' DA D 6 -6.137 -3.872 4.646 1.00 84.43 C ANISOU 470 C2' DA D 6 15179 8530 8370 -308 -626 -6 C ATOM 471 C1' DA D 6 -7.103 -3.150 5.585 1.00 88.71 C ANISOU 471 C1' DA D 6 15544 9261 8901 -413 -472 165 C ATOM 472 N9 DA D 6 -7.080 -1.689 5.529 1.00 79.17 N ANISOU 472 N9 DA D 6 14036 8286 7757 -319 -325 106 N ATOM 473 C8 DA D 6 -5.981 -0.889 5.388 0.96 66.77 C ANISOU 473 C8 DA D 6 12365 6772 6233 -76 -297 -79 C ATOM 474 N7 DA D 6 -6.262 0.389 5.400 1.00 56.40 N ANISOU 474 N7 DA D 6 10774 5672 4983 -49 -167 -83 N ATOM 475 C5 DA D 6 -7.638 0.440 5.557 1.00 56.65 C ANISOU 475 C5 DA D 6 10719 5805 4998 -284 -103 105 C ATOM 476 C6 DA D 6 -8.561 1.510 5.641 1.00 62.07 C ANISOU 476 C6 DA D 6 11139 6723 5721 -374 25 187 C ATOM 477 N6 DA D 6 -8.212 2.809 5.575 1.00 54.12 N ANISOU 477 N6 DA D 6 9891 5884 4788 -232 112 89 N ATOM 478 N1 DA D 6 -9.867 1.197 5.825 1.00 66.87 N ANISOU 478 N1 DA D 6 11737 7387 6285 -617 54 376 N ATOM 479 C2 DA D 6 -10.222 -0.089 5.901 1.00 59.45 C ANISOU 479 C2 DA D 6 11032 6273 5284 -766 -38 482 C ATOM 480 N3 DA D 6 -9.444 -1.166 5.822 0.83 66.62 N ANISOU 480 N3 DA D 6 12201 6947 6163 -703 -169 423 N ATOM 481 C4 DA D 6 -8.156 -0.836 5.651 1.00 65.17 C ANISOU 481 C4 DA D 6 12028 6723 6012 -455 -196 227 C ATOM 482 P DC D 7 -6.678 -7.006 4.193 1.00 98.63 P ANISOU 482 P DC D 7 17569 9820 10086 -604 -1001 139 P ATOM 483 OP1 DC D 7 -6.775 -8.412 4.650 1.00 95.46 O ANISOU 483 OP1 DC D 7 17470 9180 9621 -698 -1162 232 O ATOM 484 OP2 DC D 7 -5.667 -6.619 3.178 1.00 91.95 O ANISOU 484 OP2 DC D 7 16666 8988 9281 -407 -1042 -91 O ATOM 485 O5' DC D 7 -8.093 -6.475 3.650 1.00 75.45 O ANISOU 485 O5' DC D 7 14406 7041 7219 -850 -891 289 O ATOM 486 C5' DC D 7 -9.197 -6.396 4.531 1.00 81.77 C ANISOU 486 C5' DC D 7 15147 7930 7991 -1038 -793 510 C ATOM 487 C4' DC D 7 -10.294 -5.489 4.009 1.00 87.64 C ANISOU 487 C4' DC D 7 15615 8887 8797 -1197 -654 589 C ATOM 488 O4' DC D 7 -9.849 -4.108 4.047 1.00 83.27 O ANISOU 488 O4' DC D 7 14818 8548 8273 -1025 -512 477 O ATOM 489 C3' DC D 7 -10.772 -5.766 2.583 1.00 97.43 C ANISOU 489 C3' DC D 7 16826 10077 10115 -1324 -721 554 C ATOM 490 O3' DC D 7 -12.186 -6.007 2.586 1.00100.84 O ANISOU 490 O3' DC D 7 17210 10548 10558 -1603 -686 752 O ATOM 491 C2' DC D 7 -10.394 -4.503 1.796 1.00 90.85 C ANISOU 491 C2' DC D 7 15740 9430 9348 -1185 -614 400 C ATOM 492 C1' DC D 7 -10.361 -3.445 2.900 1.00 90.22 C ANISOU 492 C1' DC D 7 15495 9548 9236 -1100 -454 438 C ATOM 493 N1 DC D 7 -9.509 -2.240 2.623 1.00 80.14 N ANISOU 493 N1 DC D 7 14024 8416 8008 -877 -368 268 N ATOM 494 C2 DC D 7 -10.098 -0.980 2.555 1.00 72.22 C ANISOU 494 C2 DC D 7 12737 7653 7051 -909 -214 294 C ATOM 495 O2 DC D 7 -11.319 -0.903 2.721 1.00 67.53 O ANISOU 495 O2 DC D 7 12062 7153 6444 -1118 -150 451 O ATOM 496 N3 DC D 7 -9.313 0.111 2.304 1.00 65.60 N ANISOU 496 N3 DC D 7 11721 6934 6269 -711 -146 146 N ATOM 497 C4 DC D 7 -7.992 -0.041 2.138 1.00 59.44 C ANISOU 497 C4 DC D 7 11038 6050 5496 -491 -220 -20 C ATOM 498 N4 DC D 7 -7.247 1.046 1.913 1.00 59.95 N ANISOU 498 N4 DC D 7 10918 6236 5623 -307 -152 -152 N ATOM 499 C5 DC D 7 -7.375 -1.322 2.204 0.59 69.39 C ANISOU 499 C5 DC D 7 12590 7078 6698 -451 -375 -57 C ATOM 500 C6 DC D 7 -8.162 -2.377 2.452 1.00 81.07 C ANISOU 500 C6 DC D 7 14244 8433 8126 -646 -447 88 C ATOM 501 P DA D 8 -12.910 -6.678 1.323 1.00122.10 P ANISOU 501 P DA D 8 19936 13134 13323 -1786 -787 766 P ATOM 502 OP1 DA D 8 -13.930 -7.614 1.844 0.48125.23 O ANISOU 502 OP1 DA D 8 20459 13427 13695 -2038 -840 985 O ATOM 503 OP2 DA D 8 -11.878 -7.149 0.370 1.00109.53 O ANISOU 503 OP2 DA D 8 18466 11386 11764 -1618 -939 567 O ATOM 504 O5' DA D 8 -13.666 -5.445 0.649 1.00115.77 O ANISOU 504 O5' DA D 8 18824 12585 12580 -1849 -620 757 O ATOM 505 C5' DA D 8 -14.726 -4.834 1.364 1.00111.74 C ANISOU 505 C5' DA D 8 18152 12266 12039 -2005 -471 923 C ATOM 506 C4' DA D 8 -15.288 -3.648 0.600 1.00106.59 C ANISOU 506 C4' DA D 8 17217 11842 11442 -2032 -331 874 C ATOM 507 O4' DA D 8 -14.336 -2.549 0.605 1.00 96.42 O ANISOU 507 O4' DA D 8 15783 10683 10167 -1790 -250 719 O ATOM 508 C3' DA D 8 -15.647 -3.911 -0.861 1.00104.08 C ANISOU 508 C3' DA D 8 16876 11465 11207 -2110 -392 802 C ATOM 509 O3' DA D 8 -16.897 -3.281 -1.094 1.00103.00 O ANISOU 509 O3' DA D 8 16537 11512 11086 -2294 -268 894 O ATOM 510 C2' DA D 8 -14.503 -3.250 -1.629 1.00 98.89 C ANISOU 510 C2' DA D 8 16137 10841 10595 -1859 -391 586 C ATOM 511 C1' DA D 8 -14.174 -2.067 -0.720 1.00 91.51 C ANISOU 511 C1' DA D 8 15037 10106 9627 -1735 -242 579 C ATOM 512 N9 DA D 8 -12.808 -1.553 -0.816 1.00 79.84 N ANISOU 512 N9 DA D 8 13538 8632 8166 -1464 -249 403 N ATOM 513 C8 DA D 8 -11.651 -2.281 -0.897 0.72 81.16 C ANISOU 513 C8 DA D 8 13904 8615 8320 -1299 -385 288 C ATOM 514 N7 DA D 8 -10.558 -1.559 -0.951 1.00 74.21 N ANISOU 514 N7 DA D 8 12944 7796 7458 -1067 -354 139 N ATOM 515 C5 DA D 8 -11.032 -0.258 -0.902 1.00 69.55 C ANISOU 515 C5 DA D 8 12083 7438 6904 -1082 -190 161 C ATOM 516 C6 DA D 8 -10.359 0.989 -0.918 1.00 59.00 C ANISOU 516 C6 DA D 8 10543 6260 5613 -900 -93 53 C ATOM 517 N6 DA D 8 -9.020 1.121 -0.990 1.00 51.79 N ANISOU 517 N6 DA D 8 9667 5296 4714 -664 -138 -101 N ATOM 518 N1 DA D 8 -11.141 2.086 -0.839 1.00 44.16 N ANISOU 518 N1 DA D 8 8421 4593 3764 -974 47 111 N ATOM 519 C2 DA D 8 -12.478 1.953 -0.747 0.57 49.91 C ANISOU 519 C2 DA D 8 9113 5384 4469 -1208 92 259 C ATOM 520 N3 DA D 8 -13.227 0.849 -0.725 1.00 55.70 N ANISOU 520 N3 DA D 8 10013 5991 5160 -1399 19 375 N ATOM 521 C4 DA D 8 -12.423 -0.232 -0.809 1.00 70.47 C ANISOU 521 C4 DA D 8 12125 7639 7013 -1322 -125 319 C ATOM 522 P DG D 9 -17.646 -3.331 -2.499 1.00106.22 P ANISOU 522 P DG D 9 16860 11925 11574 -2415 -281 852 P ATOM 523 OP1 DG D 9 -19.088 -3.457 -2.187 1.00100.61 O ANISOU 523 OP1 DG D 9 16094 11291 10842 -2685 -219 1035 O ATOM 524 OP2 DG D 9 -16.924 -4.256 -3.397 1.00103.76 O ANISOU 524 OP2 DG D 9 16723 11389 11313 -2324 -457 731 O ATOM 525 O5' DG D 9 -17.426 -1.868 -3.095 1.00104.38 O ANISOU 525 O5' DG D 9 16358 11922 11378 -2279 -137 721 O ATOM 526 C5' DG D 9 -18.130 -0.808 -2.464 1.00100.63 C ANISOU 526 C5' DG D 9 15678 11690 10867 -2345 26 801 C ATOM 527 C4' DG D 9 -17.858 0.520 -3.145 1.00 86.21 C ANISOU 527 C4' DG D 9 13611 10054 9091 -2211 137 667 C ATOM 528 O4' DG D 9 -16.465 0.870 -3.001 1.00 66.90 O ANISOU 528 O4' DG D 9 11182 7578 6660 -1954 114 536 O ATOM 529 C3' DG D 9 -18.168 0.582 -4.636 1.00 87.76 C ANISOU 529 C3' DG D 9 13729 10251 9364 -2241 128 574 C ATOM 530 O3' DG D 9 -18.856 1.788 -4.831 1.00 86.46 O ANISOU 530 O3' DG D 9 13317 10325 9209 -2285 277 574 O ATOM 531 C2' DG D 9 -16.807 0.607 -5.327 1.00 77.81 C ANISOU 531 C2' DG D 9 12506 8904 8153 -1997 56 400 C ATOM 532 C1' DG D 9 -15.933 1.251 -4.247 1.00 79.11 C ANISOU 532 C1' DG D 9 12642 9135 8282 -1832 106 383 C ATOM 533 N9 DG D 9 -14.550 0.795 -4.285 1.00 79.43 N ANISOU 533 N9 DG D 9 12828 9024 8327 -1622 -3 266 N ATOM 534 C8 DG D 9 -14.097 -0.505 -4.342 1.00 77.83 C ANISOU 534 C8 DG D 9 12880 8588 8105 -1609 -166 253 C ATOM 535 N7 DG D 9 -12.798 -0.606 -4.373 1.00 67.05 N ANISOU 535 N7 DG D 9 11595 7142 6738 -1390 -237 125 N ATOM 536 C5 DG D 9 -12.378 0.717 -4.323 1.00 68.12 C ANISOU 536 C5 DG D 9 11510 7468 6904 -1257 -108 58 C ATOM 537 C6 DG D 9 -11.073 1.228 -4.319 1.00 67.17 C ANISOU 537 C6 DG D 9 11354 7365 6801 -1013 -111 -80 C ATOM 538 O6 DG D 9 -10.028 0.561 -4.376 1.00 67.10 O ANISOU 538 O6 DG D 9 11513 7210 6771 -864 -230 -176 O ATOM 539 N1 DG D 9 -11.063 2.627 -4.253 1.00 72.04 N ANISOU 539 N1 DG D 9 11716 8192 7464 -949 33 -102 N ATOM 540 C2 DG D 9 -12.193 3.429 -4.199 1.00 70.79 C ANISOU 540 C2 DG D 9 11366 8208 7322 -1099 159 -10 C ATOM 541 N2 DG D 9 -11.988 4.771 -4.153 1.00 59.20 N ANISOU 541 N2 DG D 9 9664 6924 5905 -1003 272 -54 N ATOM 542 N3 DG D 9 -13.437 2.939 -4.188 1.00 58.46 N ANISOU 542 N3 DG D 9 9842 6641 5731 -1328 165 115 N ATOM 543 C4 DG D 9 -13.437 1.593 -4.266 1.00 66.50 C ANISOU 543 C4 DG D 9 11100 7453 6715 -1394 31 143 C ATOM 544 P DG D 10 -19.599 2.064 -6.207 1.00 96.56 P ANISOU 544 P DG D 10 14466 11673 10551 -2368 316 516 P ATOM 545 OP1 DG D 10 -21.010 2.349 -5.860 1.00 89.75 O ANISOU 545 OP1 DG D 10 13501 10957 9644 -2593 410 641 O ATOM 546 OP2 DG D 10 -19.230 0.997 -7.174 1.00 97.32 O ANISOU 546 OP2 DG D 10 14722 11558 10697 -2339 172 445 O ATOM 547 O5' DG D 10 -18.911 3.425 -6.678 1.00 88.28 O ANISOU 547 O5' DG D 10 13202 10792 9549 -2172 411 383 O ATOM 548 C5' DG D 10 -18.889 4.538 -5.779 1.00 84.05 C ANISOU 548 C5' DG D 10 12511 10442 8982 -2123 520 410 C ATOM 549 C4' DG D 10 -18.014 5.629 -6.373 1.00 77.64 C ANISOU 549 C4' DG D 10 11531 9730 8240 -1917 572 272 C ATOM 550 O4' DG D 10 -16.620 5.242 -6.255 1.00 74.47 O ANISOU 550 O4' DG D 10 11253 9184 7858 -1716 482 190 O ATOM 551 C3' DG D 10 -18.288 5.861 -7.856 1.00 74.04 C ANISOU 551 C3' DG D 10 10971 9311 7850 -1925 594 188 C ATOM 552 O3' DG D 10 -18.211 7.250 -8.144 1.00 76.87 O ANISOU 552 O3' DG D 10 11090 9865 8251 -1840 704 129 O ATOM 553 C2' DG D 10 -17.193 5.049 -8.545 1.00 65.64 C ANISOU 553 C2' DG D 10 10054 8060 6824 -1774 470 90 C ATOM 554 C1' DG D 10 -16.044 5.142 -7.539 1.00 70.39 C ANISOU 554 C1' DG D 10 10724 8614 7407 -1609 439 71 C ATOM 555 N9 DG D 10 -15.123 4.008 -7.634 1.00 65.08 N ANISOU 555 N9 DG D 10 10276 7726 6725 -1510 292 20 N ATOM 556 C8 DG D 10 -15.427 2.680 -7.821 1.00 69.49 C ANISOU 556 C8 DG D 10 11045 8099 7258 -1613 169 57 C ATOM 557 N7 DG D 10 -14.373 1.908 -7.896 1.00 68.91 N ANISOU 557 N7 DG D 10 11143 7859 7178 -1471 39 -19 N ATOM 558 C5 DG D 10 -13.302 2.785 -7.757 1.00 63.25 C ANISOU 558 C5 DG D 10 10321 7229 6483 -1263 87 -111 C ATOM 559 C6 DG D 10 -11.909 2.528 -7.755 1.00 73.10 C ANISOU 559 C6 DG D 10 11665 8382 7727 -1046 -2 -224 C ATOM 560 O6 DG D 10 -11.334 1.431 -7.886 1.00 79.56 O ANISOU 560 O6 DG D 10 12695 9018 8515 -988 -151 -271 O ATOM 561 N1 DG D 10 -11.173 3.710 -7.591 1.00 73.95 N ANISOU 561 N1 DG D 10 11595 8631 7872 -886 92 -288 N ATOM 562 C2 DG D 10 -11.720 4.978 -7.446 1.00 72.74 C ANISOU 562 C2 DG D 10 11203 8677 7757 -929 242 -249 C ATOM 563 N2 DG D 10 -10.863 6.011 -7.306 1.00 66.72 N ANISOU 563 N2 DG D 10 10290 8019 7043 -757 302 -320 N ATOM 564 N3 DG D 10 -13.031 5.222 -7.427 1.00 62.97 N ANISOU 564 N3 DG D 10 9880 7533 6513 -1128 320 -148 N ATOM 565 C4 DG D 10 -13.750 4.080 -7.595 1.00 60.33 C ANISOU 565 C4 DG D 10 9715 7069 6140 -1287 240 -85 C ATOM 566 P DG D 11 -18.730 7.840 -9.544 0.65 73.69 P ANISOU 566 P DG D 11 10520 9571 7907 -1864 770 60 P ATOM 567 OP1 DG D 11 -19.861 8.731 -9.213 1.00 77.28 O ANISOU 567 OP1 DG D 11 10808 10225 8329 -2002 883 119 O ATOM 568 OP2 DG D 11 -18.844 6.791 -10.584 1.00 67.58 O ANISOU 568 OP2 DG D 11 9871 8653 7154 -1898 685 24 O ATOM 569 O5' DG D 11 -17.479 8.701 -9.999 0.78 70.70 O ANISOU 569 O5' DG D 11 10018 9240 7605 -1626 786 -53 O ATOM 570 C5' DG D 11 -16.667 9.302 -9.022 1.00 59.31 C ANISOU 570 C5' DG D 11 8538 7831 6166 -1497 797 -57 C ATOM 571 C4' DG D 11 -15.319 9.528 -9.677 1.00 50.72 C ANISOU 571 C4' DG D 11 7419 6701 5150 -1275 762 -169 C ATOM 572 O4' DG D 11 -14.597 8.278 -9.570 1.00 64.87 O ANISOU 572 O4' DG D 11 9445 8290 6911 -1216 636 -190 O ATOM 573 C3' DG D 11 -15.350 9.916 -11.143 1.00 56.24 C ANISOU 573 C3' DG D 11 7986 7468 5913 -1235 796 -240 C ATOM 574 O3' DG D 11 -14.584 11.108 -11.271 1.00 49.14 O ANISOU 574 O3' DG D 11 6898 6685 5088 -1080 853 -295 O ATOM 575 C2' DG D 11 -14.727 8.704 -11.857 1.00 61.01 C ANISOU 575 C2' DG D 11 8771 7899 6512 -1164 674 -297 C ATOM 576 C1' DG D 11 -13.894 8.046 -10.757 1.00 55.97 C ANISOU 576 C1' DG D 11 8319 7118 5831 -1091 586 -288 C ATOM 577 N9 DG D 11 -13.776 6.599 -10.860 1.00 53.67 N ANISOU 577 N9 DG D 11 8271 6628 5493 -1118 451 -290 N ATOM 578 C8 DG D 11 -14.791 5.676 -10.930 1.00 57.77 C ANISOU 578 C8 DG D 11 8916 7061 5973 -1304 406 -222 C ATOM 579 N7 DG D 11 -14.367 4.440 -11.023 1.00 58.20 N ANISOU 579 N7 DG D 11 9188 6924 6000 -1276 263 -245 N ATOM 580 C5 DG D 11 -12.982 4.559 -11.002 1.00 57.21 C ANISOU 580 C5 DG D 11 9084 6767 5887 -1055 214 -340 C ATOM 581 C6 DG D 11 -11.985 3.555 -11.060 1.00 68.17 C ANISOU 581 C6 DG D 11 10673 7983 7248 -925 60 -412 C ATOM 582 O6 DG D 11 -12.141 2.318 -11.150 1.00 66.06 O ANISOU 582 O6 DG D 11 10612 7543 6946 -983 -75 -403 O ATOM 583 N1 DG D 11 -10.700 4.116 -11.010 1.00 62.94 N ANISOU 583 N1 DG D 11 9950 7362 6602 -708 65 -504 N ATOM 584 C2 DG D 11 -10.423 5.461 -10.917 1.00 63.82 C ANISOU 584 C2 DG D 11 9836 7646 6765 -631 195 -517 C ATOM 585 N2 DG D 11 -9.119 5.798 -10.883 1.00 62.01 N ANISOU 585 N2 DG D 11 9580 7426 6554 -421 173 -608 N ATOM 586 N3 DG D 11 -11.359 6.410 -10.851 1.00 54.06 N ANISOU 586 N3 DG D 11 8414 6564 5562 -752 330 -448 N ATOM 587 C4 DG D 11 -12.604 5.881 -10.904 1.00 51.66 C ANISOU 587 C4 DG D 11 8168 6233 5228 -958 332 -365 C ATOM 588 P DT D 12 -14.260 11.793 -12.646 1.00 61.57 P ANISOU 588 P DT D 12 8296 8355 6742 -979 898 -367 P ATOM 589 OP1 DT D 12 -13.920 13.215 -12.374 1.00 68.46 O ANISOU 589 OP1 DT D 12 8951 9374 7685 -896 977 -376 O ATOM 590 OP2 DT D 12 -15.346 11.442 -13.577 1.00 70.31 O ANISOU 590 OP2 DT D 12 9397 9487 7829 -1118 922 -357 O ATOM 591 O5' DT D 12 -12.928 11.090 -13.146 1.00 60.19 O ANISOU 591 O5' DT D 12 8231 8055 6583 -794 796 -447 O ATOM 592 C5' DT D 12 -11.787 11.224 -12.311 1.00 52.43 C ANISOU 592 C5' DT D 12 7288 7021 5614 -648 757 -474 C ATOM 593 C4' DT D 12 -10.625 10.546 -13.004 1.00 46.39 C ANISOU 593 C4' DT D 12 6614 6159 4852 -478 660 -561 C ATOM 594 O4' DT D 12 -10.872 9.117 -13.002 1.00 48.80 O ANISOU 594 O4' DT D 12 7162 6300 5080 -545 549 -558 O ATOM 595 C3' DT D 12 -10.479 10.932 -14.457 1.00 48.29 C ANISOU 595 C3' DT D 12 6702 6500 5146 -404 690 -610 C ATOM 596 O3' DT D 12 -9.212 11.500 -14.508 1.00 45.22 O ANISOU 596 O3' DT D 12 6224 6147 4811 -212 685 -665 O ATOM 597 C2' DT D 12 -10.560 9.614 -15.241 1.00 51.43 C ANISOU 597 C2' DT D 12 7273 6780 5488 -408 579 -649 C ATOM 598 C1' DT D 12 -10.315 8.557 -14.164 1.00 47.26 C ANISOU 598 C1' DT D 12 6999 6069 4888 -433 472 -637 C ATOM 599 N1 DT D 12 -10.998 7.242 -14.280 1.00 46.73 N ANISOU 599 N1 DT D 12 7140 5857 4759 -555 373 -617 N ATOM 600 C2 DT D 12 -10.252 6.093 -14.218 1.00 49.28 C ANISOU 600 C2 DT D 12 7678 6013 5032 -466 221 -672 C ATOM 601 O2 DT D 12 -9.034 6.115 -14.121 0.89 58.72 O ANISOU 601 O2 DT D 12 8898 7187 6225 -285 170 -744 O ATOM 602 N3 DT D 12 -10.994 4.939 -14.276 1.00 46.07 N ANISOU 602 N3 DT D 12 7453 5470 4583 -598 127 -641 N ATOM 603 C4 DT D 12 -12.380 4.807 -14.403 1.00 59.61 C ANISOU 603 C4 DT D 12 9153 7198 6298 -808 174 -562 C ATOM 604 O4 DT D 12 -12.961 3.704 -14.483 1.00 50.69 O ANISOU 604 O4 DT D 12 8192 5929 5139 -918 73 -538 O ATOM 605 C5 DT D 12 -13.088 6.070 -14.443 1.00 57.12 C ANISOU 605 C5 DT D 12 8605 7072 6024 -887 343 -515 C ATOM 606 C7 DT D 12 -14.585 6.132 -14.556 1.00 58.44 C ANISOU 606 C7 DT D 12 8725 7292 6187 -1107 416 -438 C ATOM 607 C6 DT D 12 -12.368 7.192 -14.369 1.00 54.39 C ANISOU 607 C6 DT D 12 8090 6856 5721 -757 427 -544 C ATOM 608 P DG D 13 -8.601 12.101 -15.820 1.00 51.67 P ANISOU 608 P DG D 13 6855 7085 5694 -73 715 -715 P ATOM 609 OP1 DG D 13 -7.531 13.016 -15.426 1.00 48.96 O ANISOU 609 OP1 DG D 13 6383 6797 5423 72 743 -736 O ATOM 610 OP2 DG D 13 -9.665 12.621 -16.729 1.00 47.95 O ANISOU 610 OP2 DG D 13 6229 6739 5250 -180 807 -680 O ATOM 611 O5' DG D 13 -7.890 10.817 -16.466 1.00 63.28 O ANISOU 611 O5' DG D 13 8503 8441 7100 41 578 -792 O ATOM 612 C5' DG D 13 -6.660 10.323 -15.908 1.00 55.89 C ANISOU 612 C5' DG D 13 7698 7403 6133 189 480 -853 C ATOM 613 C4' DG D 13 -6.065 9.189 -16.750 0.95 50.95 C ANISOU 613 C4' DG D 13 7212 6703 5444 305 343 -936 C ATOM 614 O4' DG D 13 -6.924 8.018 -16.658 1.00 53.85 O ANISOU 614 O4' DG D 13 7787 6932 5742 170 260 -920 O ATOM 615 C3' DG D 13 -5.909 9.441 -18.243 1.00 48.75 C ANISOU 615 C3' DG D 13 6771 6559 5192 403 358 -972 C ATOM 616 O3' DG D 13 -4.819 8.682 -18.759 1.00 53.52 O ANISOU 616 O3' DG D 13 7467 7125 5743 589 227 -1067 O ATOM 617 C2' DG D 13 -7.191 8.838 -18.808 1.00 53.40 C ANISOU 617 C2' DG D 13 7415 7120 5754 252 349 -944 C ATOM 618 C1' DG D 13 -7.195 7.566 -17.988 1.00 48.88 C ANISOU 618 C1' DG D 13 7130 6341 5103 200 215 -959 C ATOM 619 N9 DG D 13 -8.455 6.851 -17.913 0.76 48.90 N ANISOU 619 N9 DG D 13 7252 6252 5076 8 192 -910 N ATOM 620 C8 DG D 13 -9.724 7.376 -17.881 1.00 48.17 C ANISOU 620 C8 DG D 13 7061 6227 5015 -177 309 -830 C ATOM 621 N7 DG D 13 -10.644 6.463 -17.758 1.00 49.90 N ANISOU 621 N7 DG D 13 7434 6329 5195 -328 249 -799 N ATOM 622 C5 DG D 13 -9.937 5.269 -17.682 1.00 50.07 C ANISOU 622 C5 DG D 13 7673 6188 5163 -238 77 -859 C ATOM 623 C6 DG D 13 -10.395 3.944 -17.554 1.00 50.20 C ANISOU 623 C6 DG D 13 7919 6022 5132 -329 -63 -856 C ATOM 624 O6 DG D 13 -11.574 3.555 -17.489 1.00 55.46 O ANISOU 624 O6 DG D 13 8636 6637 5799 -518 -55 -791 O ATOM 625 N1 DG D 13 -9.333 3.033 -17.522 1.00 50.82 N ANISOU 625 N1 DG D 13 8174 5974 5162 -175 -231 -939 N ATOM 626 C2 DG D 13 -7.997 3.367 -17.611 1.00 52.88 C ANISOU 626 C2 DG D 13 8391 6290 5412 39 -254 -1019 C ATOM 627 N2 DG D 13 -7.089 2.375 -17.563 1.00 63.05 N ANISOU 627 N2 DG D 13 9872 7447 6638 172 -431 -1105 N ATOM 628 N3 DG D 13 -7.567 4.603 -17.737 1.00 52.46 N ANISOU 628 N3 DG D 13 8117 6409 5407 119 -117 -1016 N ATOM 629 C4 DG D 13 -8.587 5.495 -17.766 1.00 51.37 C ANISOU 629 C4 DG D 13 7809 6385 5324 -28 40 -933 C ATOM 630 P DT D 14 -3.993 9.189 -20.028 1.00 57.69 P ANISOU 630 P DT D 14 7794 7826 6300 780 240 -1114 P ATOM 631 OP1 DT D 14 -2.836 9.984 -19.546 0.52 60.06 O ANISOU 631 OP1 DT D 14 7993 8183 6646 908 277 -1128 O ATOM 632 OP2 DT D 14 -4.921 9.818 -21.004 1.00 54.44 O ANISOU 632 OP2 DT D 14 7188 7555 5940 707 348 -1062 O ATOM 633 O5' DT D 14 -3.450 7.771 -20.540 1.00 63.70 O ANISOU 633 O5' DT D 14 8758 8489 6957 904 48 -1217 O ATOM 634 C5' DT D 14 -2.920 6.899 -19.554 1.00 54.24 C ANISOU 634 C5' DT D 14 7807 7112 5690 924 -73 -1265 C ATOM 635 C4' DT D 14 -3.047 5.443 -19.939 0.75 57.93 C ANISOU 635 C4' DT D 14 8499 7445 6066 945 -257 -1334 C ATOM 636 O4' DT D 14 -4.399 4.935 -19.756 1.00 60.76 O ANISOU 636 O4' DT D 14 8961 7699 6428 734 -256 -1270 O ATOM 637 C3' DT D 14 -2.675 5.149 -21.394 1.00 58.31 C ANISOU 637 C3' DT D 14 8460 7610 6085 1112 -335 -1410 C ATOM 638 O3' DT D 14 -1.977 3.919 -21.391 1.00 66.46 O ANISOU 638 O3' DT D 14 9715 8519 7019 1233 -542 -1517 O ATOM 639 C2' DT D 14 -4.025 5.021 -22.097 1.00 49.38 C ANISOU 639 C2' DT D 14 7281 6497 4985 971 -297 -1361 C ATOM 640 C1' DT D 14 -4.775 4.284 -20.996 1.00 61.24 C ANISOU 640 C1' DT D 14 9017 7784 6466 778 -345 -1318 C ATOM 641 N1 DT D 14 -6.222 4.458 -21.106 1.00 58.38 N ANISOU 641 N1 DT D 14 8607 7423 6151 569 -251 -1233 N ATOM 642 C2 DT D 14 -7.079 3.403 -20.902 1.00 57.86 C ANISOU 642 C2 DT D 14 8737 7189 6058 429 -351 -1219 C ATOM 643 O2 DT D 14 -6.703 2.267 -20.658 1.00 60.42 O ANISOU 643 O2 DT D 14 9285 7350 6321 471 -528 -1275 O ATOM 644 N3 DT D 14 -8.404 3.748 -21.001 1.00 54.86 N ANISOU 644 N3 DT D 14 8278 6841 5726 236 -239 -1138 N ATOM 645 C4 DT D 14 -8.918 5.008 -21.262 1.00 55.42 C ANISOU 645 C4 DT D 14 8108 7090 5861 178 -47 -1078 C ATOM 646 O4 DT D 14 -10.127 5.224 -21.323 1.00 56.61 O ANISOU 646 O4 DT D 14 8209 7261 6042 4 39 -1017 O ATOM 647 C5 DT D 14 -7.945 6.055 -21.466 1.00 54.21 C ANISOU 647 C5 DT D 14 7764 7096 5738 334 39 -1095 C ATOM 648 C7 DT D 14 -8.352 7.460 -21.780 0.99 48.22 C ANISOU 648 C7 DT D 14 6739 6528 5054 293 230 -1034 C ATOM 649 C6 DT D 14 -6.659 5.732 -21.384 1.00 54.54 C ANISOU 649 C6 DT D 14 7873 7110 5739 518 -64 -1167 C ATOM 650 P DT D 15 -1.192 3.415 -22.687 0.67 65.95 P ANISOU 650 P DT D 15 9607 8564 6888 1469 -680 -1631 P ATOM 651 OP1 DT D 15 0.036 2.766 -22.161 0.91 72.74 O ANISOU 651 OP1 DT D 15 10644 9338 7658 1622 -830 -1734 O ATOM 652 OP2 DT D 15 -1.101 4.465 -23.725 1.00 61.21 O ANISOU 652 OP2 DT D 15 8704 8208 6343 1553 -549 -1600 O ATOM 653 O5' DT D 15 -2.171 2.255 -23.193 1.00 56.48 O ANISOU 653 O5' DT D 15 8561 7240 5658 1391 -818 -1654 O ATOM 654 C5' DT D 15 -2.220 1.125 -22.316 1.00 57.51 C ANISOU 654 C5' DT D 15 8989 7130 5732 1322 -973 -1684 C ATOM 655 C4' DT D 15 -3.267 0.145 -22.790 0.80 60.63 C ANISOU 655 C4' DT D 15 9503 7407 6127 1221 -1089 -1687 C ATOM 656 O4' DT D 15 -4.551 0.803 -22.788 1.00 57.11 O ANISOU 656 O4' DT D 15 8930 6998 5769 1012 -914 -1569 O ATOM 657 C3' DT D 15 -3.067 -0.385 -24.212 1.00 62.37 C ANISOU 657 C3' DT D 15 9664 7724 6311 1409 -1230 -1791 C ATOM 658 O3' DT D 15 -3.059 -1.782 -24.074 1.00 63.59 O ANISOU 658 O3' DT D 15 10083 7675 6405 1423 -1470 -1867 O ATOM 659 C2' DT D 15 -4.275 0.131 -24.999 1.00 61.47 C ANISOU 659 C2' DT D 15 9363 7712 6279 1297 -1098 -1721 C ATOM 660 C1' DT D 15 -5.294 0.342 -23.879 0.70 62.06 C ANISOU 660 C1' DT D 15 9518 7651 6412 1015 -977 -1597 C ATOM 661 N1 DT D 15 -6.307 1.398 -24.066 1.00 57.07 N ANISOU 661 N1 DT D 15 8676 7142 5864 863 -756 -1494 N ATOM 662 C2 DT D 15 -7.619 1.051 -23.844 1.00 55.89 C ANISOU 662 C2 DT D 15 8600 6881 5753 644 -736 -1428 C ATOM 663 O2 DT D 15 -7.970 -0.082 -23.520 1.00 59.87 O ANISOU 663 O2 DT D 15 9327 7186 6233 568 -893 -1442 O ATOM 664 N3 DT D 15 -8.501 2.085 -24.019 0.77 52.14 N ANISOU 664 N3 DT D 15 7927 6538 5347 517 -531 -1345 N ATOM 665 C4 DT D 15 -8.212 3.393 -24.361 1.00 53.01 C ANISOU 665 C4 DT D 15 7785 6861 5495 581 -355 -1316 C ATOM 666 O4 DT D 15 -9.095 4.246 -24.480 1.00 54.79 O ANISOU 666 O4 DT D 15 7854 7186 5778 454 -187 -1245 O ATOM 667 C5 DT D 15 -6.807 3.677 -24.564 1.00 47.17 C ANISOU 667 C5 DT D 15 6981 6219 4724 807 -389 -1377 C ATOM 668 C7 DT D 15 -6.371 5.060 -24.962 1.00 53.70 C ANISOU 668 C7 DT D 15 7533 7271 5599 889 -215 -1342 C ATOM 669 C6 DT D 15 -5.927 2.682 -24.398 1.00 47.58 C ANISOU 669 C6 DT D 15 7221 6155 4701 936 -582 -1464 C ATOM 670 P DC D 16 -2.945 -2.715 -25.358 0.64 57.80 P ANISOU 670 P DC D 16 9369 6969 5622 1609 -1690 -1993 P ATOM 671 OP1 DC D 16 -2.171 -3.901 -24.958 1.00 65.19 O ANISOU 671 OP1 DC D 16 10572 7733 6463 1713 -1944 -2102 O ATOM 672 OP2 DC D 16 -2.513 -1.868 -26.487 1.00 54.34 O ANISOU 672 OP2 DC D 16 8649 6812 5187 1791 -1596 -2022 O ATOM 673 O5' DC D 16 -4.466 -3.137 -25.559 1.00 57.12 O ANISOU 673 O5' DC D 16 9322 6766 5616 1401 -1689 -1928 O ATOM 674 C5' DC D 16 -5.181 -3.819 -24.535 1.00 57.61 C ANISOU 674 C5' DC D 16 9612 6577 5699 1176 -1739 -1860 C ATOM 675 C4' DC D 16 -6.606 -3.987 -25.037 1.00 65.67 C ANISOU 675 C4' DC D 16 10588 7561 6804 1009 -1707 -1804 C ATOM 676 O4' DC D 16 -7.186 -2.672 -25.242 1.00 57.07 O ANISOU 676 O4' DC D 16 9241 6662 5780 921 -1436 -1712 O ATOM 677 C3' DC D 16 -6.752 -4.726 -26.365 1.00 59.07 C ANISOU 677 C3' DC D 16 9726 6754 5965 1169 -1891 -1919 C ATOM 678 O3' DC D 16 -7.654 -5.816 -26.166 1.00 72.21 O ANISOU 678 O3' DC D 16 11587 8182 7668 1015 -2045 -1906 O ATOM 679 C2' DC D 16 -7.317 -3.668 -27.328 1.00 60.18 C ANISOU 679 C2' DC D 16 9567 7133 6164 1186 -1687 -1888 C ATOM 680 C1' DC D 16 -8.037 -2.724 -26.350 1.00 54.91 C ANISOU 680 C1' DC D 16 8845 6463 5557 925 -1434 -1733 C ATOM 681 N1 DC D 16 -8.171 -1.292 -26.748 1.00 49.45 N ANISOU 681 N1 DC D 16 7868 6016 4906 930 -1178 -1675 N ATOM 682 C2 DC D 16 -9.427 -0.734 -26.938 1.00 55.94 C ANISOU 682 C2 DC D 16 8567 6886 5802 750 -1014 -1595 C ATOM 683 O2 DC D 16 -10.420 -1.448 -26.787 1.00 65.29 O ANISOU 683 O2 DC D 16 9877 7913 7019 588 -1080 -1572 O ATOM 684 N3 DC D 16 -9.524 0.572 -27.279 1.00 57.21 N ANISOU 684 N3 DC D 16 8476 7263 5998 757 -792 -1545 N ATOM 685 C4 DC D 16 -8.425 1.310 -27.423 0.77 54.05 C ANISOU 685 C4 DC D 16 7944 7023 5572 928 -732 -1562 C ATOM 686 N4 DC D 16 -8.565 2.596 -27.766 0.99 50.19 N ANISOU 686 N4 DC D 16 7206 6737 5129 924 -521 -1504 N ATOM 687 C5 DC D 16 -7.132 0.752 -27.237 1.00 52.04 C ANISOU 687 C5 DC D 16 7804 6726 5241 1110 -893 -1642 C ATOM 688 C6 DC D 16 -7.052 -0.538 -26.901 1.00 49.89 C ANISOU 688 C6 DC D 16 7786 6243 4925 1107 -1112 -1701 C ATOM 689 P DT D 17 -8.104 -6.842 -27.324 1.00 71.61 P ANISOU 689 P DT D 17 11544 8050 7616 1122 -2276 -2015 P ATOM 690 OP1 DT D 17 -8.609 -8.056 -26.646 1.00 75.56 O ANISOU 690 OP1 DT D 17 12320 8250 8138 962 -2470 -1994 O ATOM 691 OP2 DT D 17 -7.033 -6.921 -28.346 1.00 65.13 O ANISOU 691 OP2 DT D 17 10628 7398 6719 1448 -2403 -2164 O ATOM 692 O5' DT D 17 -9.341 -6.133 -28.041 1.00 61.28 O ANISOU 692 O5' DT D 17 10013 6869 6402 1010 -2084 -1955 O ATOM 693 C5' DT D 17 -10.453 -5.782 -27.259 1.00 66.66 C ANISOU 693 C5' DT D 17 10709 7467 7152 710 -1914 -1811 C ATOM 694 C4' DT D 17 -11.630 -5.373 -28.107 1.00 68.50 C ANISOU 694 C4' DT D 17 10761 7800 7466 635 -1793 -1793 C ATOM 695 O4' DT D 17 -11.492 -3.992 -28.495 1.00 60.13 O ANISOU 695 O4' DT D 17 9436 7005 6405 692 -1543 -1763 O ATOM 696 C3' DT D 17 -11.847 -6.154 -29.403 1.00 68.78 C ANISOU 696 C3' DT D 17 10771 7837 7526 809 -1989 -1925 C ATOM 697 O3' DT D 17 -13.242 -6.427 -29.405 1.00 80.90 O ANISOU 697 O3' DT D 17 12328 9259 9152 588 -1959 -1867 O ATOM 698 C2' DT D 17 -11.422 -5.158 -30.492 1.00 68.13 C ANISOU 698 C2' DT D 17 10407 8058 7422 1028 -1852 -1981 C ATOM 699 C1' DT D 17 -11.870 -3.848 -29.850 0.63 64.42 C ANISOU 699 C1' DT D 17 9799 7699 6979 832 -1539 -1841 C ATOM 700 N1 DT D 17 -11.148 -2.615 -30.186 1.00 56.68 N ANISOU 700 N1 DT D 17 8589 6979 5966 970 -1353 -1830 N ATOM 701 C2 DT D 17 -11.847 -1.459 -30.452 1.00 54.72 C ANISOU 701 C2 DT D 17 8124 6900 5767 878 -1102 -1759 C ATOM 702 O2 DT D 17 -13.057 -1.385 -30.468 0.75 54.81 O ANISOU 702 O2 DT D 17 8116 6870 5839 695 -1018 -1713 O ATOM 703 N3 DT D 17 -11.067 -0.368 -30.712 1.00 54.89 N ANISOU 703 N3 DT D 17 7946 7145 5763 1011 -954 -1744 N ATOM 704 C4 DT D 17 -9.687 -0.319 -30.715 1.00 61.19 C ANISOU 704 C4 DT D 17 8738 8019 6493 1217 -1024 -1791 C ATOM 705 O4 DT D 17 -9.088 0.732 -30.941 1.00 62.86 O ANISOU 705 O4 DT D 17 8754 8433 6697 1312 -875 -1761 O ATOM 706 C5 DT D 17 -9.021 -1.572 -30.435 1.00 57.40 C ANISOU 706 C5 DT D 17 8494 7363 5954 1309 -1288 -1875 C ATOM 707 C7 DT D 17 -7.528 -1.669 -30.410 1.00 61.29 C ANISOU 707 C7 DT D 17 9008 7922 6358 1536 -1393 -1945 C ATOM 708 C6 DT D 17 -9.771 -2.642 -30.161 0.88 51.39 C ANISOU 708 C6 DT D 17 7935 6372 5218 1180 -1440 -1889 C ATOM 709 P DG D 18 -14.008 -7.170 -30.595 1.00 78.97 P ANISOU 709 P DG D 18 12051 8979 8976 668 -2116 -1971 P ATOM 710 OP1 DG D 18 -15.108 -7.949 -29.991 1.00 87.29 O ANISOU 710 OP1 DG D 18 13275 9782 10107 400 -2188 -1898 O ATOM 711 OP2 DG D 18 -13.010 -7.843 -31.456 1.00 81.58 O ANISOU 711 OP2 DG D 18 12400 9345 9253 989 -2362 -2132 O ATOM 712 O5' DG D 18 -14.646 -5.934 -31.365 1.00 84.39 O ANISOU 712 O5' DG D 18 12447 9923 9695 672 -1845 -1952 O ATOM 713 C5' DG D 18 -15.821 -5.365 -30.824 1.00 85.17 C ANISOU 713 C5' DG D 18 12504 10005 9850 386 -1635 -1829 C ATOM 714 C4' DG D 18 -16.419 -4.365 -31.796 1.00 80.13 C ANISOU 714 C4' DG D 18 11598 9605 9242 437 -1430 -1849 C ATOM 715 O4' DG D 18 -15.523 -3.245 -31.923 1.00 69.51 O ANISOU 715 O4' DG D 18 10081 8493 7838 579 -1266 -1836 O ATOM 716 C3' DG D 18 -16.663 -4.865 -33.216 1.00 80.76 C ANISOU 716 C3' DG D 18 11587 9741 9358 651 -1564 -1993 C ATOM 717 O3' DG D 18 -18.008 -4.598 -33.550 1.00 89.38 O ANISOU 717 O3' DG D 18 12588 10850 10524 496 -1436 -1972 O ATOM 718 C2' DG D 18 -15.723 -4.048 -34.100 1.00 70.59 C ANISOU 718 C2' DG D 18 10082 8731 8009 936 -1484 -2056 C ATOM 719 C1' DG D 18 -15.491 -2.805 -33.256 1.00 62.50 C ANISOU 719 C1' DG D 18 8974 7819 6953 797 -1222 -1925 C ATOM 720 N9 DG D 18 -14.165 -2.254 -33.446 1.00 54.46 N ANISOU 720 N9 DG D 18 7857 6974 5862 1018 -1200 -1947 N ATOM 721 C8 DG D 18 -12.970 -2.940 -33.388 1.00 55.20 C ANISOU 721 C8 DG D 18 8065 7020 5889 1207 -1406 -2017 C ATOM 722 N7 DG D 18 -11.928 -2.186 -33.601 1.00 58.39 N ANISOU 722 N7 DG D 18 8330 7623 6234 1381 -1326 -2020 N ATOM 723 C5 DG D 18 -12.473 -0.920 -33.808 1.00 58.68 C ANISOU 723 C5 DG D 18 8147 7839 6308 1298 -1053 -1940 C ATOM 724 C6 DG D 18 -11.828 0.306 -34.077 1.00 55.24 C ANISOU 724 C6 DG D 18 7491 7648 5850 1401 -867 -1897 C ATOM 725 O6 DG D 18 -10.605 0.492 -34.177 1.00 55.12 O ANISOU 725 O6 DG D 18 7428 7741 5774 1590 -906 -1920 O ATOM 726 N1 DG D 18 -12.749 1.352 -34.213 1.00 53.08 N ANISOU 726 N1 DG D 18 7047 7488 5633 1259 -624 -1820 N ATOM 727 C2 DG D 18 -14.117 1.203 -34.090 0.67 53.40 C ANISOU 727 C2 DG D 18 7131 7425 5733 1045 -569 -1797 C ATOM 728 N2 DG D 18 -14.877 2.297 -34.237 1.00 49.70 N ANISOU 728 N2 DG D 18 6489 7092 5303 932 -335 -1732 N ATOM 729 N3 DG D 18 -14.730 0.056 -33.840 1.00 58.66 N ANISOU 729 N3 DG D 18 7998 7868 6422 944 -737 -1833 N ATOM 730 C4 DG D 18 -13.848 -0.953 -33.716 1.00 58.35 C ANISOU 730 C4 DG D 18 8123 7710 6339 1079 -975 -1901 C TER 731 DG D 18 ATOM 732 N SER A 437 1.415 16.326 -31.191 1.00177.55 N ANISOU 732 N SER A 437 23491 22055 21914 -2769 2245 -1865 N ATOM 733 CA SER A 437 1.880 17.582 -31.762 1.00180.44 C ANISOU 733 CA SER A 437 24072 22333 22155 -2924 2425 -1864 C ATOM 734 C SER A 437 0.916 18.715 -31.432 1.00171.34 C ANISOU 734 C SER A 437 23084 21116 20900 -2842 2297 -1651 C ATOM 735 O SER A 437 1.243 19.888 -31.605 1.00175.44 O ANISOU 735 O SER A 437 23768 21548 21342 -2939 2422 -1630 O ATOM 736 CB SER A 437 2.038 17.447 -33.268 1.00188.74 C ANISOU 736 CB SER A 437 25365 23348 23001 -3096 2571 -1901 C ATOM 737 N HIS A 438 -0.270 18.361 -30.949 1.00158.77 N ANISOU 737 N HIS A 438 21447 19563 19314 -2666 2053 -1500 N ATOM 738 CA HIS A 438 -1.312 19.350 -30.703 1.00143.51 C ANISOU 738 CA HIS A 438 19666 17575 17285 -2570 1912 -1298 C ATOM 739 C HIS A 438 -1.789 19.390 -29.255 1.00123.37 C ANISOU 739 C HIS A 438 16901 15063 14910 -2394 1749 -1239 C ATOM 740 O HIS A 438 -1.286 18.660 -28.402 1.00115.37 O ANISOU 740 O HIS A 438 15630 14118 14087 -2345 1739 -1351 O ATOM 741 CB HIS A 438 -2.496 19.107 -31.635 1.00147.08 C ANISOU 741 CB HIS A 438 20320 18028 17537 -2530 1765 -1150 C ATOM 742 CG HIS A 438 -2.593 20.102 -32.746 1.00150.64 C ANISOU 742 CG HIS A 438 21116 18373 17747 -2642 1849 -1066 C ATOM 743 ND1 HIS A 438 -2.806 21.445 -32.521 1.00151.98 N ANISOU 743 ND1 HIS A 438 21447 18442 17856 -2623 1853 -953 N ATOM 744 CD2 HIS A 438 -2.506 19.953 -34.089 1.00150.19 C ANISOU 744 CD2 HIS A 438 21294 18287 17485 -2775 1934 -1076 C ATOM 745 CE1 HIS A 438 -2.846 22.081 -33.677 1.00152.40 C ANISOU 745 CE1 HIS A 438 21827 18402 17676 -2735 1932 -891 C ATOM 746 NE2 HIS A 438 -2.667 21.200 -34.644 1.00152.00 N ANISOU 746 NE2 HIS A 438 21830 18395 17528 -2832 1982 -964 N ATOM 747 N MET A 439 -2.774 20.248 -28.998 1.00107.20 N ANISOU 747 N MET A 439 14972 12969 12792 -2297 1619 -1065 N ATOM 748 CA MET A 439 -3.206 20.548 -27.640 1.00 94.81 C ANISOU 748 CA MET A 439 13237 11416 11369 -2150 1495 -1008 C ATOM 749 C MET A 439 -4.718 20.385 -27.453 1.00 80.68 C ANISOU 749 C MET A 439 11464 9655 9535 -1987 1256 -841 C ATOM 750 O MET A 439 -5.508 21.030 -28.149 1.00 67.35 O ANISOU 750 O MET A 439 9996 7913 7683 -1968 1191 -708 O ATOM 751 CB MET A 439 -2.814 21.987 -27.304 1.00 93.62 C ANISOU 751 CB MET A 439 13194 11166 11211 -2196 1601 -983 C ATOM 752 CG MET A 439 -2.646 22.264 -25.821 1.00 84.90 C ANISOU 752 CG MET A 439 11877 10083 10298 -2106 1562 -1009 C ATOM 753 SD MET A 439 -2.102 23.956 -25.489 1.00 96.59 S ANISOU 753 SD MET A 439 13492 11441 11767 -2184 1712 -999 S ATOM 754 CE MET A 439 -3.541 24.898 -26.012 1.00 89.59 C ANISOU 754 CE MET A 439 12892 10456 10693 -2086 1573 -761 C ATOM 755 N CYS A 440 -5.116 19.527 -26.514 1.00 74.32 N ANISOU 755 N CYS A 440 10429 8933 8874 -1871 1126 -853 N ATOM 756 CA CYS A 440 -6.525 19.405 -26.127 1.00 66.19 C ANISOU 756 CA CYS A 440 9375 7939 7837 -1719 913 -717 C ATOM 757 C CYS A 440 -7.137 20.774 -25.835 1.00 61.13 C ANISOU 757 C CYS A 440 8857 7218 7150 -1652 865 -586 C ATOM 758 O CYS A 440 -6.571 21.558 -25.075 1.00 67.80 O ANISOU 758 O CYS A 440 9666 8015 8080 -1661 948 -612 O ATOM 759 CB CYS A 440 -6.660 18.528 -24.883 1.00 67.39 C ANISOU 759 CB CYS A 440 9264 8168 8172 -1621 823 -763 C ATOM 760 SG CYS A 440 -8.363 18.360 -24.309 1.00 51.85 S ANISOU 760 SG CYS A 440 7242 6247 6214 -1453 587 -621 S ATOM 761 N LEU A 441 -8.284 21.067 -26.444 1.00 52.38 N ANISOU 761 N LEU A 441 7896 6096 5910 -1581 729 -452 N ATOM 762 CA LEU A 441 -8.938 22.377 -26.271 1.00 57.69 C ANISOU 762 CA LEU A 441 8706 6683 6532 -1501 671 -323 C ATOM 763 C LEU A 441 -9.721 22.458 -24.964 1.00 61.20 C ANISOU 763 C LEU A 441 8965 7164 7125 -1350 541 -278 C ATOM 764 O LEU A 441 -10.298 23.499 -24.637 1.00 67.61 O ANISOU 764 O LEU A 441 9852 7909 7928 -1265 489 -183 O ATOM 765 CB LEU A 441 -9.926 22.638 -27.403 1.00 66.05 C ANISOU 765 CB LEU A 441 9983 7716 7396 -1459 548 -198 C ATOM 766 CG LEU A 441 -9.432 23.398 -28.632 1.00 82.01 C ANISOU 766 CG LEU A 441 12312 9629 9217 -1577 664 -167 C ATOM 767 CD1 LEU A 441 -7.934 23.221 -28.852 1.00 81.43 C ANISOU 767 CD1 LEU A 441 12242 9535 9163 -1763 906 -313 C ATOM 768 CD2 LEU A 441 -10.229 22.925 -29.842 1.00 80.47 C ANISOU 768 CD2 LEU A 441 12266 9469 8839 -1565 535 -100 C ATOM 769 N VAL A 442 -9.781 21.346 -24.240 1.00 47.81 N ANISOU 769 N VAL A 442 7038 5567 5559 -1316 490 -348 N ATOM 770 CA VAL A 442 -10.486 21.327 -22.961 1.00 55.87 C ANISOU 770 CA VAL A 442 7884 6626 6718 -1191 382 -319 C ATOM 771 C VAL A 442 -9.502 21.437 -21.810 1.00 49.21 C ANISOU 771 C VAL A 442 6899 5775 6025 -1221 490 -411 C ATOM 772 O VAL A 442 -9.595 22.362 -20.992 1.00 52.88 O ANISOU 772 O VAL A 442 7353 6189 6549 -1172 498 -377 O ATOM 773 CB VAL A 442 -11.359 20.078 -22.820 1.00 58.86 C ANISOU 773 CB VAL A 442 8119 7112 7134 -1128 242 -323 C ATOM 774 CG1 VAL A 442 -11.864 19.925 -21.393 1.00 52.86 C ANISOU 774 CG1 VAL A 442 7168 6390 6527 -1030 171 -323 C ATOM 775 CG2 VAL A 442 -12.526 20.171 -23.779 1.00 59.72 C ANISOU 775 CG2 VAL A 442 8349 7234 7107 -1072 104 -224 C ATOM 776 N CYS A 443 -8.538 20.525 -21.755 1.00 53.14 N ANISOU 776 N CYS A 443 7290 6318 6584 -1299 572 -534 N ATOM 777 CA CYS A 443 -7.615 20.494 -20.633 1.00 59.11 C ANISOU 777 CA CYS A 443 7890 7082 7487 -1315 647 -632 C ATOM 778 C CYS A 443 -6.169 20.861 -20.982 1.00 70.62 C ANISOU 778 C CYS A 443 9385 8499 8948 -1448 833 -746 C ATOM 779 O CYS A 443 -5.312 20.898 -20.094 1.00 63.54 O ANISOU 779 O CYS A 443 8356 7613 8174 -1466 896 -842 O ATOM 780 CB CYS A 443 -7.642 19.105 -20.001 1.00 59.40 C ANISOU 780 CB CYS A 443 7736 7206 7627 -1272 575 -696 C ATOM 781 SG CYS A 443 -6.552 17.924 -20.784 0.94 51.70 S ANISOU 781 SG CYS A 443 6720 6269 6654 -1375 669 -836 S ATOM 782 N SER A 444 -5.891 21.103 -22.263 1.00 69.18 N ANISOU 782 N SER A 444 9379 8275 8632 -1547 921 -745 N ATOM 783 CA SER A 444 -4.536 21.449 -22.720 1.00 64.84 C ANISOU 783 CA SER A 444 8876 7685 8075 -1696 1120 -866 C ATOM 784 C SER A 444 -3.465 20.342 -22.583 1.00 55.77 C ANISOU 784 C SER A 444 7545 6608 7038 -1753 1192 -1037 C ATOM 785 O SER A 444 -2.282 20.599 -22.803 1.00 66.87 O ANISOU 785 O SER A 444 8942 7994 8471 -1872 1360 -1164 O ATOM 786 CB SER A 444 -4.047 22.724 -22.030 1.00 66.58 C ANISOU 786 CB SER A 444 9120 7833 8343 -1723 1212 -875 C ATOM 787 OG SER A 444 -4.787 23.842 -22.482 1.00 70.89 O ANISOU 787 OG SER A 444 9889 8285 8763 -1703 1194 -736 O ATOM 788 N ASP A 445 -3.870 19.126 -22.235 1.00 49.82 N ANISOU 788 N ASP A 445 6647 5931 6349 -1669 1071 -1047 N ATOM 789 CA ASP A 445 -2.999 17.949 -22.371 1.00 70.05 C ANISOU 789 CA ASP A 445 9074 8550 8991 -1711 1124 -1195 C ATOM 790 C ASP A 445 -2.673 17.761 -23.869 1.00 73.81 C ANISOU 790 C ASP A 445 9701 9008 9335 -1838 1238 -1236 C ATOM 791 O ASP A 445 -3.217 18.461 -24.726 1.00 60.59 O ANISOU 791 O ASP A 445 8239 7282 7502 -1879 1249 -1136 O ATOM 792 CB ASP A 445 -3.716 16.700 -21.819 1.00 71.84 C ANISOU 792 CB ASP A 445 9170 8843 9283 -1595 962 -1169 C ATOM 793 CG ASP A 445 -2.768 15.530 -21.535 1.00 78.29 C ANISOU 793 CG ASP A 445 9814 9706 10225 -1598 994 -1323 C ATOM 794 OD1 ASP A 445 -1.531 15.733 -21.545 1.00 85.23 O ANISOU 794 OD1 ASP A 445 10630 10579 11173 -1673 1128 -1460 O ATOM 795 OD2 ASP A 445 -3.276 14.402 -21.290 1.00 70.56 O ANISOU 795 OD2 ASP A 445 8761 8768 9281 -1523 885 -1311 O ATOM 796 N GLU A 446 -1.788 16.836 -24.212 1.00 71.25 N ANISOU 796 N GLU A 446 9282 8720 9068 -1899 1323 -1385 N ATOM 797 CA GLU A 446 -1.555 16.607 -25.631 1.00 82.11 C ANISOU 797 CA GLU A 446 10808 10080 10310 -2023 1432 -1425 C ATOM 798 C GLU A 446 -2.773 15.902 -26.200 1.00 76.10 C ANISOU 798 C GLU A 446 10130 9347 9438 -1964 1286 -1311 C ATOM 799 O GLU A 446 -3.169 14.842 -25.710 1.00 68.43 O ANISOU 799 O GLU A 446 9020 8431 8548 -1873 1169 -1318 O ATOM 800 CB GLU A 446 -0.289 15.801 -25.900 1.00 97.27 C ANISOU 800 CB GLU A 446 12600 12032 12327 -2107 1574 -1629 C ATOM 801 CG GLU A 446 0.108 15.844 -27.373 1.00117.47 C ANISOU 801 CG GLU A 446 15337 14559 14737 -2270 1736 -1687 C ATOM 802 CD GLU A 446 1.388 15.100 -27.671 1.00137.02 C ANISOU 802 CD GLU A 446 17680 17064 17318 -2359 1895 -1907 C ATOM 803 OE1 GLU A 446 1.770 14.226 -26.866 1.00140.33 O ANISOU 803 OE1 GLU A 446 17871 17534 17913 -2266 1834 -1999 O ATOM 804 OE2 GLU A 446 2.009 15.389 -28.716 1.00148.85 O ANISOU 804 OE2 GLU A 446 19307 18529 18721 -2521 2081 -1991 O ATOM 805 N ALA A 447 -3.380 16.507 -27.219 1.00 85.22 N ANISOU 805 N ALA A 447 11517 10460 10403 -2017 1287 -1208 N ATOM 806 CA ALA A 447 -4.563 15.934 -27.855 1.00 80.78 C ANISOU 806 CA ALA A 447 11043 9929 9719 -1968 1142 -1104 C ATOM 807 C ALA A 447 -4.202 14.687 -28.657 1.00 79.77 C ANISOU 807 C ALA A 447 10893 9845 9571 -2042 1195 -1216 C ATOM 808 O ALA A 447 -3.032 14.447 -28.954 1.00 76.23 O ANISOU 808 O ALA A 447 10407 9388 9169 -2146 1365 -1366 O ATOM 809 CB ALA A 447 -5.218 16.947 -28.739 1.00 72.07 C ANISOU 809 CB ALA A 447 10202 8767 8416 -1999 1122 -972 C ATOM 810 N SER A 448 -5.221 13.904 -29.000 1.00 73.69 N ANISOU 810 N SER A 448 10141 9122 8735 -1989 1053 -1152 N ATOM 811 CA SER A 448 -5.031 12.629 -29.685 1.00 72.99 C ANISOU 811 CA SER A 448 10026 9076 8632 -2046 1084 -1251 C ATOM 812 C SER A 448 -5.823 12.539 -30.981 1.00 74.59 C ANISOU 812 C SER A 448 10437 9287 8618 -2104 1034 -1181 C ATOM 813 O SER A 448 -5.607 11.621 -31.765 1.00 85.40 O ANISOU 813 O SER A 448 11830 10680 9938 -2182 1087 -1268 O ATOM 814 CB SER A 448 -5.428 11.461 -28.765 1.00 73.07 C ANISOU 814 CB SER A 448 9829 9142 8792 -1933 962 -1273 C ATOM 815 OG SER A 448 -6.835 11.385 -28.582 1.00 70.35 O ANISOU 815 OG SER A 448 9502 8832 8394 -1841 774 -1139 O ATOM 816 N GLY A 449 -6.740 13.475 -31.209 1.00 73.12 N ANISOU 816 N GLY A 449 10402 9079 8300 -2062 927 -1028 N ATOM 817 CA GLY A 449 -7.565 13.442 -32.409 1.00 75.16 C ANISOU 817 CA GLY A 449 10864 9351 8344 -2100 847 -952 C ATOM 818 C GLY A 449 -8.894 14.129 -32.194 1.00 75.87 C ANISOU 818 C GLY A 449 11011 9449 8368 -1975 644 -783 C ATOM 819 O GLY A 449 -9.158 14.634 -31.116 1.00 77.99 O ANISOU 819 O GLY A 449 11165 9709 8760 -1866 580 -728 O ATOM 820 N CYS A 450 -9.732 14.156 -33.220 1.00 67.10 N ANISOU 820 N CYS A 450 10075 8356 7064 -1987 538 -707 N ATOM 821 CA CYS A 450 -11.034 14.806 -33.126 1.00 68.76 C ANISOU 821 CA CYS A 450 10340 8578 7206 -1858 330 -555 C ATOM 822 C CYS A 450 -12.004 13.851 -32.462 1.00 68.58 C ANISOU 822 C CYS A 450 10102 8657 7300 -1755 167 -558 C ATOM 823 O CYS A 450 -12.308 12.786 -32.993 1.00 69.24 O ANISOU 823 O CYS A 450 10159 8808 7341 -1799 127 -615 O ATOM 824 CB CYS A 450 -11.558 15.232 -34.520 1.00 69.64 C ANISOU 824 CB CYS A 450 10733 8671 7054 -1904 263 -474 C ATOM 825 SG CYS A 450 -11.016 16.887 -35.085 1.00 96.24 S ANISOU 825 SG CYS A 450 14412 11896 10260 -1957 370 -383 S ATOM 826 N HIS A 451 -12.477 14.228 -31.282 1.00 70.29 N ANISOU 826 N HIS A 451 10167 8878 7661 -1629 84 -506 N ATOM 827 CA HIS A 451 -13.447 13.421 -30.557 1.00 59.93 C ANISOU 827 CA HIS A 451 8655 7653 6461 -1536 -61 -507 C ATOM 828 C HIS A 451 -14.697 14.227 -30.243 1.00 55.11 C ANISOU 828 C HIS A 451 8044 7059 5836 -1400 -243 -384 C ATOM 829 O HIS A 451 -14.616 15.343 -29.741 1.00 53.68 O ANISOU 829 O HIS A 451 7897 6812 5687 -1336 -233 -314 O ATOM 830 CB HIS A 451 -12.808 12.881 -29.286 1.00 53.70 C ANISOU 830 CB HIS A 451 7653 6864 5887 -1517 23 -587 C ATOM 831 CG HIS A 451 -11.516 12.173 -29.534 1.00 52.76 C ANISOU 831 CG HIS A 451 7521 6723 5803 -1632 199 -716 C ATOM 832 ND1 HIS A 451 -11.458 10.922 -30.117 1.00 53.85 N ANISOU 832 ND1 HIS A 451 7638 6907 5916 -1702 216 -805 N ATOM 833 CD2 HIS A 451 -10.235 12.548 -29.315 1.00 54.02 C ANISOU 833 CD2 HIS A 451 7682 6819 6023 -1689 367 -783 C ATOM 834 CE1 HIS A 451 -10.193 10.553 -30.225 1.00 62.78 C ANISOU 834 CE1 HIS A 451 8753 8001 7098 -1787 386 -919 C ATOM 835 NE2 HIS A 451 -9.431 11.521 -29.748 1.00 63.88 N ANISOU 835 NE2 HIS A 451 8899 8081 7292 -1782 479 -912 N ATOM 836 N TYR A 452 -15.848 13.658 -30.587 1.00 54.51 N ANISOU 836 N TYR A 452 7928 7071 5713 -1358 -407 -367 N ATOM 837 CA TYR A 452 -17.142 14.295 -30.374 1.00 60.48 C ANISOU 837 CA TYR A 452 8658 7860 6460 -1223 -598 -270 C ATOM 838 C TYR A 452 -17.185 15.693 -30.984 1.00 69.25 C ANISOU 838 C TYR A 452 9992 8888 7431 -1179 -632 -157 C ATOM 839 O TYR A 452 -17.924 16.564 -30.526 1.00 65.62 O ANISOU 839 O TYR A 452 9514 8412 7006 -1049 -744 -73 O ATOM 840 CB TYR A 452 -17.479 14.269 -28.873 1.00 62.95 C ANISOU 840 CB TYR A 452 8744 8190 6984 -1129 -616 -277 C ATOM 841 CG TYR A 452 -17.539 12.841 -28.396 1.00 62.97 C ANISOU 841 CG TYR A 452 8566 8265 7094 -1176 -597 -380 C ATOM 842 CD1 TYR A 452 -18.410 11.937 -29.004 1.00 60.81 C ANISOU 842 CD1 TYR A 452 8259 8087 6759 -1199 -707 -414 C ATOM 843 CD2 TYR A 452 -16.699 12.373 -27.384 1.00 60.02 C ANISOU 843 CD2 TYR A 452 8070 7861 6873 -1202 -468 -447 C ATOM 844 CE1 TYR A 452 -18.462 10.621 -28.614 1.00 57.10 C ANISOU 844 CE1 TYR A 452 7648 7669 6378 -1252 -679 -509 C ATOM 845 CE2 TYR A 452 -16.749 11.047 -26.971 1.00 60.68 C ANISOU 845 CE2 TYR A 452 8017 7995 7045 -1240 -452 -534 C ATOM 846 CZ TYR A 452 -17.633 10.173 -27.596 1.00 62.42 C ANISOU 846 CZ TYR A 452 8217 8298 7201 -1269 -551 -564 C ATOM 847 OH TYR A 452 -17.699 8.848 -27.214 1.00 55.32 O ANISOU 847 OH TYR A 452 7202 7436 6382 -1316 -526 -652 O ATOM 848 N GLY A 453 -16.385 15.879 -32.037 1.00 74.51 N ANISOU 848 N GLY A 453 10878 9496 7935 -1292 -529 -162 N ATOM 849 CA GLY A 453 -16.408 17.086 -32.842 1.00 72.18 C ANISOU 849 CA GLY A 453 10851 9113 7463 -1274 -556 -55 C ATOM 850 C GLY A 453 -15.275 18.059 -32.568 1.00 73.36 C ANISOU 850 C GLY A 453 11113 9131 7628 -1325 -367 -41 C ATOM 851 O GLY A 453 -15.183 19.102 -33.210 1.00 68.57 O ANISOU 851 O GLY A 453 10754 8428 6871 -1325 -361 47 O ATOM 852 N VAL A 454 -14.406 17.730 -31.618 1.00 75.46 N ANISOU 852 N VAL A 454 11209 9390 8073 -1369 -215 -130 N ATOM 853 CA VAL A 454 -13.417 18.695 -31.144 1.00 65.46 C ANISOU 853 CA VAL A 454 10002 8012 6856 -1403 -49 -127 C ATOM 854 C VAL A 454 -12.063 18.045 -30.940 1.00 55.49 C ANISOU 854 C VAL A 454 8654 6747 5682 -1540 163 -268 C ATOM 855 O VAL A 454 -11.971 16.872 -30.597 1.00 65.95 O ANISOU 855 O VAL A 454 9791 8153 7113 -1557 166 -360 O ATOM 856 CB VAL A 454 -13.849 19.326 -29.784 1.00 72.80 C ANISOU 856 CB VAL A 454 10771 8928 7961 -1264 -109 -81 C ATOM 857 CG1 VAL A 454 -12.764 20.264 -29.246 1.00 65.88 C ANISOU 857 CG1 VAL A 454 9943 7944 7145 -1314 72 -96 C ATOM 858 CG2 VAL A 454 -15.186 20.056 -29.916 1.00 72.58 C ANISOU 858 CG2 VAL A 454 10811 8898 7869 -1111 -317 49 C ATOM 859 N LEU A 455 -11.011 18.824 -31.123 1.00 51.41 N ANISOU 859 N LEU A 455 8271 6132 5130 -1636 342 -289 N ATOM 860 CA LEU A 455 -9.671 18.346 -30.860 1.00 61.46 C ANISOU 860 CA LEU A 455 9444 7400 6507 -1757 547 -435 C ATOM 861 C LEU A 455 -9.524 18.147 -29.344 1.00 67.29 C ANISOU 861 C LEU A 455 9912 8171 7482 -1671 537 -479 C ATOM 862 O LEU A 455 -9.506 19.124 -28.573 1.00 54.91 O ANISOU 862 O LEU A 455 8334 6548 5982 -1611 545 -428 O ATOM 863 CB LEU A 455 -8.666 19.365 -31.418 1.00 64.63 C ANISOU 863 CB LEU A 455 10061 7687 6808 -1884 741 -449 C ATOM 864 CG LEU A 455 -7.163 19.111 -31.285 1.00 81.21 C ANISOU 864 CG LEU A 455 12084 9771 9002 -2028 979 -614 C ATOM 865 CD1 LEU A 455 -6.784 19.054 -29.832 1.00 91.03 C ANISOU 865 CD1 LEU A 455 13064 11040 10482 -1956 991 -671 C ATOM 866 CD2 LEU A 455 -6.742 17.837 -31.988 1.00 91.79 C ANISOU 866 CD2 LEU A 455 13378 11179 10321 -2126 1041 -735 C ATOM 867 N THR A 456 -9.442 16.895 -28.898 1.00 56.77 N ANISOU 867 N THR A 456 8374 6924 6271 -1662 518 -570 N ATOM 868 CA THR A 456 -9.257 16.645 -27.458 1.00 65.00 C ANISOU 868 CA THR A 456 9180 7992 7524 -1585 508 -612 C ATOM 869 C THR A 456 -8.298 15.511 -27.179 1.00 64.93 C ANISOU 869 C THR A 456 9012 8022 7634 -1645 607 -762 C ATOM 870 O THR A 456 -7.958 14.733 -28.072 1.00 59.21 O ANISOU 870 O THR A 456 8333 7319 6844 -1733 665 -835 O ATOM 871 CB THR A 456 -10.585 16.299 -26.716 1.00 53.43 C ANISOU 871 CB THR A 456 7586 6590 6123 -1444 311 -535 C ATOM 872 OG1 THR A 456 -10.960 14.933 -26.964 1.00 56.47 O ANISOU 872 OG1 THR A 456 7883 7057 6517 -1453 249 -588 O ATOM 873 CG2 THR A 456 -11.713 17.208 -27.144 1.00 51.50 C ANISOU 873 CG2 THR A 456 7482 6325 5758 -1366 179 -396 C ATOM 874 N CYS A 457 -7.889 15.415 -25.920 1.00 58.13 N ANISOU 874 N CYS A 457 7970 7169 6949 -1589 619 -808 N ATOM 875 CA CYS A 457 -7.110 14.290 -25.433 1.00 52.97 C ANISOU 875 CA CYS A 457 7144 6552 6432 -1603 671 -939 C ATOM 876 C CYS A 457 -8.037 13.105 -25.229 1.00 47.84 C ANISOU 876 C CYS A 457 6403 5967 5807 -1535 533 -921 C ATOM 877 O CYS A 457 -9.267 13.243 -25.277 1.00 50.98 O ANISOU 877 O CYS A 457 6838 6390 6143 -1472 397 -815 O ATOM 878 CB CYS A 457 -6.426 14.670 -24.113 1.00 56.97 C ANISOU 878 CB CYS A 457 7503 7042 7102 -1556 707 -984 C ATOM 879 SG CYS A 457 -7.572 14.831 -22.687 1.00 51.09 S ANISOU 879 SG CYS A 457 6645 6320 6448 -1403 535 -874 S ATOM 880 N GLY A 458 -7.466 11.930 -24.997 1.00 51.92 N ANISOU 880 N GLY A 458 6800 6509 6420 -1547 566 -1032 N ATOM 881 CA GLY A 458 -8.269 10.754 -24.712 1.00 50.50 C ANISOU 881 CA GLY A 458 6537 6376 6274 -1492 453 -1025 C ATOM 882 C GLY A 458 -9.043 10.855 -23.398 1.00 56.18 C ANISOU 882 C GLY A 458 7149 7110 7088 -1379 335 -953 C ATOM 883 O GLY A 458 -10.190 10.415 -23.316 1.00 53.36 O ANISOU 883 O GLY A 458 6777 6792 6706 -1336 218 -894 O ATOM 884 N SER A 459 -8.435 11.419 -22.356 1.00 61.73 N ANISOU 884 N SER A 459 7772 7784 7899 -1337 367 -966 N ATOM 885 CA SER A 459 -9.119 11.465 -21.053 1.00 54.00 C ANISOU 885 CA SER A 459 6695 6815 7006 -1238 267 -907 C ATOM 886 C SER A 459 -10.376 12.325 -21.176 1.00 40.91 C ANISOU 886 C SER A 459 5106 5169 5270 -1196 175 -782 C ATOM 887 O SER A 459 -11.436 11.943 -20.707 1.00 40.61 O ANISOU 887 O SER A 459 5015 5166 5248 -1140 70 -734 O ATOM 888 CB SER A 459 -8.198 11.959 -19.930 1.00 44.30 C ANISOU 888 CB SER A 459 5378 5556 5898 -1206 317 -949 C ATOM 889 OG SER A 459 -7.972 13.363 -20.008 1.00 44.38 O ANISOU 889 OG SER A 459 5457 5532 5874 -1224 371 -908 O ATOM 890 N CYS A 460 -10.279 13.439 -21.901 1.00 37.43 N ANISOU 890 N CYS A 460 4790 4696 4735 -1228 215 -735 N ATOM 891 CA CYS A 460 -11.439 14.304 -22.087 1.00 47.09 C ANISOU 891 CA CYS A 460 6089 5922 5882 -1173 118 -617 C ATOM 892 C CYS A 460 -12.516 13.673 -22.965 1.00 51.49 C ANISOU 892 C CYS A 460 6689 6535 6339 -1172 12 -582 C ATOM 893 O CYS A 460 -13.723 13.853 -22.721 1.00 40.15 O ANISOU 893 O CYS A 460 5224 5133 4897 -1098 -110 -511 O ATOM 894 CB CYS A 460 -10.993 15.648 -22.644 1.00 48.33 C ANISOU 894 CB CYS A 460 6394 6012 5958 -1206 192 -575 C ATOM 895 SG CYS A 460 -10.312 16.706 -21.331 0.90 42.93 S ANISOU 895 SG CYS A 460 5645 5270 5397 -1171 263 -581 S ATOM 896 N LYS A 461 -12.087 12.920 -23.978 1.00 44.93 N ANISOU 896 N LYS A 461 5918 5719 5434 -1258 61 -643 N ATOM 897 CA LYS A 461 -13.040 12.183 -24.794 1.00 52.59 C ANISOU 897 CA LYS A 461 6919 6750 6311 -1271 -37 -629 C ATOM 898 C LYS A 461 -13.912 11.303 -23.904 1.00 49.82 C ANISOU 898 C LYS A 461 6416 6454 6059 -1213 -132 -637 C ATOM 899 O LYS A 461 -15.144 11.370 -23.982 1.00 47.65 O ANISOU 899 O LYS A 461 6126 6229 5749 -1164 -256 -581 O ATOM 900 CB LYS A 461 -12.324 11.340 -25.874 1.00 50.63 C ANISOU 900 CB LYS A 461 6742 6507 5989 -1383 50 -717 C ATOM 901 CG LYS A 461 -13.179 10.210 -26.472 1.00 45.89 C ANISOU 901 CG LYS A 461 6130 5976 5330 -1406 -38 -739 C ATOM 902 CD LYS A 461 -12.404 9.458 -27.564 1.00 61.70 C ANISOU 902 CD LYS A 461 8215 7973 7253 -1523 64 -832 C ATOM 903 CE LYS A 461 -11.840 8.098 -27.121 1.00 70.14 C ANISOU 903 CE LYS A 461 9165 9044 8440 -1547 126 -946 C ATOM 904 NZ LYS A 461 -12.891 7.139 -26.657 1.00 71.81 N ANISOU 904 NZ LYS A 461 9279 9308 8697 -1508 15 -942 N ATOM 905 N VAL A 462 -13.295 10.485 -23.048 1.00 40.10 N ANISOU 905 N VAL A 462 5075 5212 4950 -1216 -76 -711 N ATOM 906 CA VAL A 462 -14.091 9.517 -22.284 1.00 47.24 C ANISOU 906 CA VAL A 462 5864 6157 5929 -1182 -150 -725 C ATOM 907 C VAL A 462 -14.839 10.211 -21.147 1.00 50.16 C ANISOU 907 C VAL A 462 6156 6530 6372 -1094 -217 -658 C ATOM 908 O VAL A 462 -15.966 9.842 -20.826 1.00 42.64 O ANISOU 908 O VAL A 462 5141 5626 5435 -1066 -304 -639 O ATOM 909 CB VAL A 462 -13.255 8.341 -21.737 1.00 66.15 C ANISOU 909 CB VAL A 462 8189 8527 8420 -1206 -81 -819 C ATOM 910 CG1 VAL A 462 -12.636 7.518 -22.912 1.00 58.55 C ANISOU 910 CG1 VAL A 462 7292 7563 7390 -1294 -15 -900 C ATOM 911 CG2 VAL A 462 -12.187 8.824 -20.732 1.00 48.29 C ANISOU 911 CG2 VAL A 462 5874 6209 6264 -1168 -11 -840 C ATOM 912 N PHE A 463 -14.227 11.230 -20.550 0.89 43.58 N ANISOU 912 N PHE A 463 5328 5646 5584 -1059 -168 -631 N ATOM 913 CA PHE A 463 -14.915 12.015 -19.527 1.00 51.63 C ANISOU 913 CA PHE A 463 6288 6663 6665 -978 -220 -570 C ATOM 914 C PHE A 463 -16.234 12.549 -20.091 1.00 45.39 C ANISOU 914 C PHE A 463 5526 5917 5803 -936 -331 -498 C ATOM 915 O PHE A 463 -17.291 12.349 -19.509 1.00 41.15 O ANISOU 915 O PHE A 463 4900 5423 5311 -891 -407 -484 O ATOM 916 CB PHE A 463 -14.068 13.199 -19.028 1.00 39.60 C ANISOU 916 CB PHE A 463 4792 5076 5178 -957 -147 -550 C ATOM 917 CG PHE A 463 -14.849 14.136 -18.154 1.00 41.32 C ANISOU 917 CG PHE A 463 4971 5287 5443 -876 -199 -484 C ATOM 918 CD1 PHE A 463 -15.018 13.856 -16.802 1.00 38.27 C ANISOU 918 CD1 PHE A 463 4476 4902 5161 -841 -206 -500 C ATOM 919 CD2 PHE A 463 -15.483 15.250 -18.696 1.00 42.76 C ANISOU 919 CD2 PHE A 463 5232 5456 5558 -833 -246 -406 C ATOM 920 CE1 PHE A 463 -15.783 14.691 -15.986 0.82 39.12 C ANISOU 920 CE1 PHE A 463 4544 5004 5314 -772 -244 -450 C ATOM 921 CE2 PHE A 463 -16.237 16.096 -17.896 1.00 40.28 C ANISOU 921 CE2 PHE A 463 4875 5132 5298 -751 -292 -353 C ATOM 922 CZ PHE A 463 -16.400 15.807 -16.533 1.00 42.16 C ANISOU 922 CZ PHE A 463 4993 5379 5648 -725 -286 -380 C ATOM 923 N PHE A 464 -16.169 13.213 -21.242 1.00 36.99 N ANISOU 923 N PHE A 464 4590 4842 4623 -951 -339 -458 N ATOM 924 CA PHE A 464 -17.366 13.798 -21.852 1.00 42.18 C ANISOU 924 CA PHE A 464 5288 5536 5202 -894 -463 -387 C ATOM 925 C PHE A 464 -18.486 12.784 -22.062 1.00 48.73 C ANISOU 925 C PHE A 464 6033 6458 6025 -898 -566 -416 C ATOM 926 O PHE A 464 -19.647 13.038 -21.742 1.00 52.12 O ANISOU 926 O PHE A 464 6385 6933 6484 -827 -670 -388 O ATOM 927 CB PHE A 464 -17.027 14.430 -23.201 1.00 49.42 C ANISOU 927 CB PHE A 464 6388 6422 5968 -926 -456 -346 C ATOM 928 CG PHE A 464 -18.203 15.103 -23.851 0.80 55.56 C ANISOU 928 CG PHE A 464 7226 7228 6657 -850 -601 -267 C ATOM 929 CD1 PHE A 464 -18.761 16.247 -23.288 1.00 55.10 C ANISOU 929 CD1 PHE A 464 7158 7136 6641 -742 -655 -195 C ATOM 930 CD2 PHE A 464 -18.765 14.586 -25.003 1.00 53.45 C ANISOU 930 CD2 PHE A 464 7021 7021 6266 -880 -690 -270 C ATOM 931 CE1 PHE A 464 -19.852 16.867 -23.872 0.89 59.05 C ANISOU 931 CE1 PHE A 464 7707 7660 7070 -652 -803 -127 C ATOM 932 CE2 PHE A 464 -19.864 15.198 -25.588 1.00 65.14 C ANISOU 932 CE2 PHE A 464 8550 8535 7667 -796 -846 -201 C ATOM 933 CZ PHE A 464 -20.401 16.343 -25.025 1.00 68.27 C ANISOU 933 CZ PHE A 464 8932 8893 8113 -675 -906 -129 C ATOM 934 N LYS A 465 -18.141 11.637 -22.625 0.94 43.38 N ANISOU 934 N LYS A 465 5367 5807 5311 -984 -534 -483 N ATOM 935 CA LYS A 465 -19.137 10.619 -22.942 1.00 48.09 C ANISOU 935 CA LYS A 465 5896 6488 5888 -1010 -620 -524 C ATOM 936 C LYS A 465 -19.768 10.084 -21.647 1.00 50.31 C ANISOU 936 C LYS A 465 6021 6794 6303 -983 -632 -554 C ATOM 937 O LYS A 465 -20.977 9.847 -21.569 1.00 46.36 O ANISOU 937 O LYS A 465 5435 6366 5816 -963 -725 -564 O ATOM 938 CB LYS A 465 -18.471 9.491 -23.751 1.00 60.45 C ANISOU 938 CB LYS A 465 7518 8057 7393 -1117 -556 -598 C ATOM 939 CG LYS A 465 -19.280 8.209 -23.863 1.00 61.99 C ANISOU 939 CG LYS A 465 7636 8325 7594 -1166 -607 -664 C ATOM 940 CD LYS A 465 -20.512 8.382 -24.712 1.00 62.39 C ANISOU 940 CD LYS A 465 7693 8464 7550 -1152 -749 -642 C ATOM 941 CE LYS A 465 -21.059 7.006 -25.105 1.00 73.07 C ANISOU 941 CE LYS A 465 8998 9884 8883 -1238 -773 -729 C ATOM 942 NZ LYS A 465 -22.486 7.077 -25.458 1.00 72.24 N ANISOU 942 NZ LYS A 465 8824 9882 8740 -1211 -924 -729 N ATOM 943 N ARG A 466 -18.954 9.919 -20.613 1.00 59.28 N ANISOU 943 N ARG A 466 7119 7869 7534 -985 -536 -575 N ATOM 944 CA ARG A 466 -19.478 9.469 -19.324 1.00 57.23 C ANISOU 944 CA ARG A 466 6741 7619 7387 -966 -536 -598 C ATOM 945 C ARG A 466 -20.374 10.522 -18.704 1.00 51.60 C ANISOU 945 C ARG A 466 5965 6922 6718 -880 -597 -545 C ATOM 946 O ARG A 466 -21.361 10.190 -18.052 1.00 51.95 O ANISOU 946 O ARG A 466 5905 7011 6822 -870 -635 -568 O ATOM 947 CB ARG A 466 -18.340 9.102 -18.375 1.00 47.59 C ANISOU 947 CB ARG A 466 5514 6324 6244 -979 -434 -629 C ATOM 948 CG ARG A 466 -17.767 7.730 -18.669 1.00 56.01 C ANISOU 948 CG ARG A 466 6600 7379 7304 -1052 -386 -702 C ATOM 949 CD ARG A 466 -16.351 7.613 -18.177 1.00 52.68 C ANISOU 949 CD ARG A 466 6199 6882 6934 -1051 -295 -731 C ATOM 950 NE ARG A 466 -15.831 6.264 -18.362 1.00 53.37 N ANISOU 950 NE ARG A 466 6299 6947 7031 -1104 -254 -805 N ATOM 951 CZ ARG A 466 -14.548 5.949 -18.250 0.53 50.84 C ANISOU 951 CZ ARG A 466 5998 6571 6750 -1106 -182 -854 C ATOM 952 NH1 ARG A 466 -13.676 6.890 -17.956 1.00 46.64 N ANISOU 952 NH1 ARG A 466 5468 6007 6248 -1071 -142 -840 N ATOM 953 NH2 ARG A 466 -14.135 4.705 -18.442 1.00 49.73 N ANISOU 953 NH2 ARG A 466 5870 6404 6623 -1143 -150 -924 N ATOM 954 N ALA A 467 -20.036 11.792 -18.920 1.00 54.77 N ANISOU 954 N ALA A 467 6434 7284 7093 -822 -599 -480 N ATOM 955 CA ALA A 467 -20.785 12.887 -18.316 1.00 60.20 C ANISOU 955 CA ALA A 467 7073 7970 7831 -730 -648 -429 C ATOM 956 C ALA A 467 -22.171 12.975 -18.940 1.00 60.88 C ANISOU 956 C ALA A 467 7110 8139 7882 -687 -780 -421 C ATOM 957 O ALA A 467 -23.155 13.162 -18.235 1.00 60.16 O ANISOU 957 O ALA A 467 6904 8086 7869 -636 -825 -432 O ATOM 958 CB ALA A 467 -20.028 14.246 -18.467 1.00 41.76 C ANISOU 958 CB ALA A 467 4845 5555 5467 -683 -609 -363 C ATOM 959 N VAL A 468 -22.259 12.840 -20.259 1.00 62.87 N ANISOU 959 N VAL A 468 7446 8424 8017 -708 -843 -411 N ATOM 960 CA VAL A 468 -23.550 12.981 -20.929 1.00 66.25 C ANISOU 960 CA VAL A 468 7831 8939 8404 -657 -991 -406 C ATOM 961 C VAL A 468 -24.432 11.785 -20.618 1.00 65.53 C ANISOU 961 C VAL A 468 7593 8939 8367 -712 -1019 -494 C ATOM 962 O VAL A 468 -25.614 11.942 -20.334 1.00 71.32 O ANISOU 962 O VAL A 468 8201 9740 9156 -659 -1105 -517 O ATOM 963 CB VAL A 468 -23.424 13.121 -22.458 1.00 71.36 C ANISOU 963 CB VAL A 468 8624 9599 8891 -671 -1062 -372 C ATOM 964 CG1 VAL A 468 -24.797 13.386 -23.066 0.91 73.15 C ANISOU 964 CG1 VAL A 468 8796 9917 9079 -594 -1239 -365 C ATOM 965 CG2 VAL A 468 -22.478 14.241 -22.815 1.00 71.61 C ANISOU 965 CG2 VAL A 468 8825 9529 8856 -641 -1010 -291 C ATOM 966 N GLU A 469 -23.856 10.588 -20.654 1.00 67.03 N ANISOU 966 N GLU A 469 7797 9124 8546 -821 -940 -553 N ATOM 967 CA GLU A 469 -24.631 9.378 -20.400 1.00 81.58 C ANISOU 967 CA GLU A 469 9527 11040 10431 -892 -950 -641 C ATOM 968 C GLU A 469 -25.010 9.243 -18.926 1.00 86.70 C ANISOU 968 C GLU A 469 10055 11675 11213 -885 -891 -671 C ATOM 969 O GLU A 469 -26.189 9.318 -18.582 1.00 90.07 O ANISOU 969 O GLU A 469 10355 12172 11697 -861 -951 -706 O ATOM 970 CB GLU A 469 -23.864 8.135 -20.853 1.00 86.15 C ANISOU 970 CB GLU A 469 10174 11598 10959 -1007 -874 -694 C ATOM 971 CG GLU A 469 -23.518 8.132 -22.332 1.00 93.63 C ANISOU 971 CG GLU A 469 11244 12563 11766 -1037 -918 -681 C ATOM 972 CD GLU A 469 -24.738 7.958 -23.229 1.00107.45 C ANISOU 972 CD GLU A 469 12950 14428 13448 -1041 -1059 -711 C ATOM 973 OE1 GLU A 469 -25.709 7.293 -22.801 1.00110.52 O ANISOU 973 OE1 GLU A 469 13205 14888 13901 -1071 -1090 -780 O ATOM 974 OE2 GLU A 469 -24.721 8.481 -24.367 1.00111.08 O ANISOU 974 OE2 GLU A 469 13514 14907 13785 -1019 -1139 -669 O ATOM 975 N GLY A 470 -24.015 9.037 -18.062 1.00 83.54 N ANISOU 975 N GLY A 470 9695 11187 10860 -909 -775 -664 N ATOM 976 CA GLY A 470 -24.267 8.802 -16.650 1.00 78.83 C ANISOU 976 CA GLY A 470 9016 10567 10368 -917 -711 -691 C ATOM 977 C GLY A 470 -25.013 9.961 -16.021 1.00 85.52 C ANISOU 977 C GLY A 470 9782 11430 11282 -824 -749 -661 C ATOM 978 O GLY A 470 -25.601 9.845 -14.938 1.00 83.79 O ANISOU 978 O GLY A 470 9471 11217 11147 -832 -711 -696 O ATOM 979 N GLN A 471 -24.974 11.090 -16.718 1.00110.35 N ANISOU 979 N GLN A 471 12972 14573 14384 -738 -818 -596 N ATOM 980 CA GLN A 471 -25.652 12.305 -16.295 1.00121.41 C ANISOU 980 CA GLN A 471 14311 15979 15842 -630 -865 -561 C ATOM 981 C GLN A 471 -25.662 12.506 -14.777 1.00120.78 C ANISOU 981 C GLN A 471 14165 15854 15870 -625 -775 -577 C ATOM 982 O GLN A 471 -26.707 12.820 -14.199 1.00118.99 O ANISOU 982 O GLN A 471 13819 15672 15722 -586 -799 -610 O ATOM 983 CB GLN A 471 -27.086 12.315 -16.824 1.00128.26 C ANISOU 983 CB GLN A 471 15061 16955 16717 -593 -991 -602 C ATOM 984 CG GLN A 471 -27.631 13.712 -17.027 1.00139.73 C ANISOU 984 CG GLN A 471 16499 18406 18185 -452 -1085 -546 C ATOM 985 CD GLN A 471 -27.198 14.309 -18.350 1.00143.92 C ANISOU 985 CD GLN A 471 17179 18914 18589 -402 -1169 -468 C ATOM 986 OE1 GLN A 471 -26.241 15.085 -18.416 1.00140.13 O ANISOU 986 OE1 GLN A 471 16835 18338 18069 -373 -1118 -392 O ATOM 987 NE2 GLN A 471 -27.893 13.937 -19.418 1.00144.56 N ANISOU 987 NE2 GLN A 471 17243 19084 18597 -401 -1294 -492 N ATOM 988 N HIS A 472 -24.511 12.329 -14.130 1.00116.71 N ANISOU 988 N HIS A 472 13727 15257 15361 -663 -673 -561 N ATOM 989 CA HIS A 472 -24.427 12.653 -12.711 1.00110.07 C ANISOU 989 CA HIS A 472 12849 14368 14604 -653 -595 -566 C ATOM 990 C HIS A 472 -24.600 14.157 -12.689 1.00113.37 C ANISOU 990 C HIS A 472 13269 14761 15046 -544 -627 -510 C ATOM 991 O HIS A 472 -24.234 14.834 -13.653 1.00118.12 O ANISOU 991 O HIS A 472 13953 15344 15584 -495 -675 -454 O ATOM 992 CB HIS A 472 -23.087 12.307 -12.029 1.00 99.28 C ANISOU 992 CB HIS A 472 11569 12919 13236 -697 -500 -558 C ATOM 993 CG HIS A 472 -22.146 11.470 -12.844 1.00 99.72 C ANISOU 993 CG HIS A 472 11709 12958 13222 -753 -489 -563 C ATOM 994 ND1 HIS A 472 -22.076 11.525 -14.220 1.00103.65 N ANISOU 994 ND1 HIS A 472 12254 13485 13641 -751 -546 -546 N ATOM 995 CD2 HIS A 472 -21.174 10.609 -12.458 1.00 98.40 C ANISOU 995 CD2 HIS A 472 11593 12741 13052 -807 -427 -587 C ATOM 996 CE1 HIS A 472 -21.139 10.700 -14.648 1.00101.98 C ANISOU 996 CE1 HIS A 472 12112 13248 13388 -810 -506 -567 C ATOM 997 NE2 HIS A 472 -20.571 10.135 -13.598 1.00 97.36 N ANISOU 997 NE2 HIS A 472 11524 12613 12853 -838 -438 -593 N ATOM 998 N ASN A 473 -25.162 14.691 -11.614 1.00106.02 N ANISOU 998 N ASN A 473 12260 13822 14201 -509 -594 -527 N ATOM 999 CA ASN A 473 -25.199 16.138 -11.471 1.00105.74 C ANISOU 999 CA ASN A 473 12240 13740 14195 -405 -607 -475 C ATOM 1000 C ASN A 473 -24.036 16.621 -10.620 1.00 93.08 C ANISOU 1000 C ASN A 473 10719 12044 12604 -417 -507 -447 C ATOM 1001 O ASN A 473 -24.000 16.445 -9.400 1.00 97.96 O ANISOU 1001 O ASN A 473 11301 12642 13277 -451 -433 -481 O ATOM 1002 CB ASN A 473 -26.549 16.629 -10.956 1.00113.36 C ANISOU 1002 CB ASN A 473 13067 14753 15253 -341 -639 -516 C ATOM 1003 CG ASN A 473 -27.425 17.171 -12.076 1.00121.48 C ANISOU 1003 CG ASN A 473 14058 15835 16263 -242 -775 -498 C ATOM 1004 OD1 ASN A 473 -28.527 16.677 -12.319 1.00123.69 O ANISOU 1004 OD1 ASN A 473 14213 16210 16575 -243 -843 -562 O ATOM 1005 ND2 ASN A 473 -26.922 18.183 -12.781 1.00123.22 N ANISOU 1005 ND2 ASN A 473 14396 15993 16428 -161 -818 -414 N ATOM 1006 N TYR A 474 -23.075 17.212 -11.317 1.00 68.19 N ANISOU 1006 N TYR A 474 7683 8836 9390 -397 -506 -389 N ATOM 1007 CA TYR A 474 -21.803 17.619 -10.749 1.00 53.45 C ANISOU 1007 CA TYR A 474 5897 6888 7522 -421 -417 -372 C ATOM 1008 C TYR A 474 -21.972 18.975 -10.117 1.00 48.65 C ANISOU 1008 C TYR A 474 5293 6226 6968 -347 -391 -344 C ATOM 1009 O TYR A 474 -22.793 19.780 -10.571 1.00 53.77 O ANISOU 1009 O TYR A 474 5928 6877 7626 -261 -453 -314 O ATOM 1010 CB TYR A 474 -20.775 17.770 -11.859 1.00 54.08 C ANISOU 1010 CB TYR A 474 6097 6934 7516 -439 -415 -335 C ATOM 1011 CG TYR A 474 -20.362 16.511 -12.564 1.00 52.32 C ANISOU 1011 CG TYR A 474 5893 6750 7236 -515 -425 -365 C ATOM 1012 CD1 TYR A 474 -19.854 15.432 -11.854 1.00 54.02 C ANISOU 1012 CD1 TYR A 474 6079 6969 7478 -582 -376 -416 C ATOM 1013 CD2 TYR A 474 -20.414 16.426 -13.951 1.00 53.04 C ANISOU 1013 CD2 TYR A 474 6049 6865 7240 -517 -481 -341 C ATOM 1014 CE1 TYR A 474 -19.432 14.294 -12.501 1.00 55.60 C ANISOU 1014 CE1 TYR A 474 6303 7191 7632 -645 -378 -447 C ATOM 1015 CE2 TYR A 474 -19.995 15.282 -14.613 1.00 53.16 C ANISOU 1015 CE2 TYR A 474 6085 6910 7202 -592 -479 -376 C ATOM 1016 CZ TYR A 474 -19.502 14.225 -13.878 1.00 53.64 C ANISOU 1016 CZ TYR A 474 6107 6970 7304 -653 -425 -431 C ATOM 1017 OH TYR A 474 -19.073 13.089 -14.504 1.00 55.94 O ANISOU 1017 OH TYR A 474 6423 7280 7552 -720 -417 -470 O ATOM 1018 N LEU A 475 -21.163 19.273 -9.113 1.00 47.12 N ANISOU 1018 N LEU A 475 5123 5975 6805 -375 -305 -356 N ATOM 1019 CA LEU A 475 -21.278 20.571 -8.473 1.00 33.11 C ANISOU 1019 CA LEU A 475 3358 4141 5080 -314 -268 -337 C ATOM 1020 C LEU A 475 -19.911 21.173 -8.214 1.00 36.40 C ANISOU 1020 C LEU A 475 3870 4482 5478 -346 -189 -326 C ATOM 1021 O LEU A 475 -19.054 20.573 -7.540 1.00 38.87 O ANISOU 1021 O LEU A 475 4184 4793 5794 -414 -139 -364 O ATOM 1022 CB LEU A 475 -22.099 20.461 -7.159 1.00 39.56 C ANISOU 1022 CB LEU A 475 4072 4980 5980 -314 -235 -387 C ATOM 1023 CG LEU A 475 -22.151 21.740 -6.287 1.00 43.78 C ANISOU 1023 CG LEU A 475 4614 5448 6573 -265 -176 -383 C ATOM 1024 CD1 LEU A 475 -22.924 22.876 -6.983 1.00 41.52 C ANISOU 1024 CD1 LEU A 475 4332 5136 6307 -150 -231 -341 C ATOM 1025 CD2 LEU A 475 -22.761 21.463 -4.898 1.00 42.45 C ANISOU 1025 CD2 LEU A 475 4360 5299 6472 -296 -121 -445 C ATOM 1026 N CYS A 476 -19.728 22.391 -8.730 1.00 37.24 N ANISOU 1026 N CYS A 476 4060 4523 5568 -295 -181 -277 N ATOM 1027 CA CYS A 476 -18.509 23.177 -8.499 1.00 28.13 C ANISOU 1027 CA CYS A 476 2995 3290 4402 -329 -95 -275 C ATOM 1028 C CYS A 476 -18.349 23.575 -7.027 1.00 33.03 C ANISOU 1028 C CYS A 476 3573 3883 5092 -341 -25 -316 C ATOM 1029 O CYS A 476 -19.301 23.934 -6.379 1.00 34.32 O ANISOU 1029 O CYS A 476 3679 4049 5313 -290 -32 -321 O ATOM 1030 CB CYS A 476 -18.537 24.458 -9.379 1.00 30.44 C ANISOU 1030 CB CYS A 476 3404 3504 4656 -270 -97 -210 C ATOM 1031 SG CYS A 476 -17.006 25.416 -9.359 1.00 32.81 S ANISOU 1031 SG CYS A 476 3832 3705 4929 -336 24 -215 S ATOM 1032 N ALA A 477 -17.124 23.555 -6.528 1.00 27.78 N ANISOU 1032 N ALA A 477 2938 3194 4423 -409 42 -352 N ATOM 1033 CA ALA A 477 -16.826 23.997 -5.181 0.94 29.59 C ANISOU 1033 CA ALA A 477 3146 3395 4702 -429 105 -393 C ATOM 1034 C ALA A 477 -16.345 25.445 -5.174 0.75 27.62 C ANISOU 1034 C ALA A 477 2978 3056 4459 -418 175 -380 C ATOM 1035 O ALA A 477 -16.056 25.995 -4.114 1.00 29.58 O ANISOU 1035 O ALA A 477 3221 3273 4746 -437 234 -417 O ATOM 1036 CB ALA A 477 -15.744 23.066 -4.513 1.00 29.89 C ANISOU 1036 CB ALA A 477 3160 3464 4732 -506 122 -452 C ATOM 1037 N GLY A 478 -16.274 26.074 -6.345 1.00 34.41 N ANISOU 1037 N GLY A 478 3928 3870 5277 -392 171 -328 N ATOM 1038 CA GLY A 478 -15.808 27.458 -6.428 1.00 30.56 C ANISOU 1038 CA GLY A 478 3544 3281 4787 -390 247 -313 C ATOM 1039 C GLY A 478 -16.899 28.404 -6.904 1.00 35.52 C ANISOU 1039 C GLY A 478 4226 3848 5421 -283 212 -244 C ATOM 1040 O GLY A 478 -17.836 28.742 -6.159 1.00 33.40 O ANISOU 1040 O GLY A 478 3895 3576 5219 -216 199 -248 O ATOM 1041 N ARG A 479 -16.761 28.831 -8.157 1.00 34.66 N ANISOU 1041 N ARG A 479 4239 3689 5243 -265 198 -185 N ATOM 1042 CA ARG A 479 -17.575 29.908 -8.721 1.00 42.50 C ANISOU 1042 CA ARG A 479 5327 4596 6226 -157 164 -111 C ATOM 1043 C ARG A 479 -17.994 29.577 -10.173 1.00 45.36 C ANISOU 1043 C ARG A 479 5759 4976 6500 -113 64 -43 C ATOM 1044 O ARG A 479 -18.372 30.468 -10.950 0.92 32.12 O ANISOU 1044 O ARG A 479 4215 3212 4777 -35 32 30 O ATOM 1045 CB ARG A 479 -16.764 31.214 -8.697 1.00 37.29 C ANISOU 1045 CB ARG A 479 4817 3803 5549 -191 278 -102 C ATOM 1046 CG ARG A 479 -16.437 31.729 -7.274 1.00 37.66 C ANISOU 1046 CG ARG A 479 4809 3822 5680 -227 374 -171 C ATOM 1047 CD ARG A 479 -15.361 32.848 -7.321 1.00 31.25 C ANISOU 1047 CD ARG A 479 4143 2890 4841 -303 504 -183 C ATOM 1048 NE ARG A 479 -15.188 33.508 -6.022 1.00 34.01 N ANISOU 1048 NE ARG A 479 4455 3201 5265 -326 589 -244 N ATOM 1049 CZ ARG A 479 -14.476 33.016 -5.006 0.61 38.90 C ANISOU 1049 CZ ARG A 479 4974 3888 5918 -417 633 -333 C ATOM 1050 NH1 ARG A 479 -14.388 33.695 -3.864 1.00 34.26 N ANISOU 1050 NH1 ARG A 479 4370 3261 5388 -435 706 -386 N ATOM 1051 NH2 ARG A 479 -13.866 31.843 -5.122 1.00 31.63 N ANISOU 1051 NH2 ARG A 479 3973 3070 4973 -484 600 -370 N ATOM 1052 N ASN A 480 -17.918 28.296 -10.525 1.00 38.58 N ANISOU 1052 N ASN A 480 4823 4223 5611 -162 13 -67 N ATOM 1053 CA ASN A 480 -18.221 27.829 -11.885 1.00 38.89 C ANISOU 1053 CA ASN A 480 4924 4294 5557 -142 -78 -16 C ATOM 1054 C ASN A 480 -17.238 28.369 -12.918 1.00 47.07 C ANISOU 1054 C ASN A 480 6153 5245 6485 -206 -14 21 C ATOM 1055 O ASN A 480 -17.587 28.506 -14.088 1.00 40.15 O ANISOU 1055 O ASN A 480 5392 4348 5515 -166 -84 86 O ATOM 1056 CB ASN A 480 -19.669 28.199 -12.293 1.00 31.89 C ANISOU 1056 CB ASN A 480 4024 3411 4681 4 -208 42 C ATOM 1057 CG ASN A 480 -20.683 27.147 -11.885 1.00 32.58 C ANISOU 1057 CG ASN A 480 3919 3626 4833 35 -297 -3 C ATOM 1058 OD1 ASN A 480 -20.325 26.030 -11.543 1.00 30.32 O ANISOU 1058 OD1 ASN A 480 3543 3422 4557 -53 -275 -59 O ATOM 1059 ND2 ASN A 480 -21.940 27.515 -11.876 1.00 32.94 N ANISOU 1059 ND2 ASN A 480 3903 3685 4929 160 -392 15 N ATOM 1060 N ASP A 481 -16.017 28.680 -12.502 1.00 38.64 N ANISOU 1060 N ASP A 481 5126 4131 5426 -309 119 -27 N ATOM 1061 CA ASP A 481 -14.981 29.114 -13.461 1.00 41.34 C ANISOU 1061 CA ASP A 481 5643 4398 5668 -398 207 -15 C ATOM 1062 C ASP A 481 -13.622 28.507 -13.124 1.00 41.73 C ANISOU 1062 C ASP A 481 5632 4487 5736 -538 316 -114 C ATOM 1063 O ASP A 481 -12.599 29.210 -13.175 1.00 36.40 O ANISOU 1063 O ASP A 481 5051 3737 5044 -626 443 -147 O ATOM 1064 CB ASP A 481 -14.868 30.657 -13.490 1.00 40.87 C ANISOU 1064 CB ASP A 481 5753 4186 5589 -373 281 33 C ATOM 1065 CG ASP A 481 -14.461 31.254 -12.138 0.94 51.10 C ANISOU 1065 CG ASP A 481 6979 5447 6990 -399 379 -29 C ATOM 1066 OD1 ASP A 481 -14.366 30.517 -11.123 0.82 51.87 O ANISOU 1066 OD1 ASP A 481 6899 5637 7173 -422 375 -101 O ATOM 1067 OD2 ASP A 481 -14.245 32.487 -12.070 1.00 64.34 O ANISOU 1067 OD2 ASP A 481 8791 6995 8659 -397 460 -6 O ATOM 1068 N CYS A 482 -13.603 27.220 -12.749 1.00 37.88 N ANISOU 1068 N CYS A 482 4987 4116 5291 -558 269 -169 N ATOM 1069 CA CYS A 482 -12.341 26.569 -12.371 1.00 39.42 C ANISOU 1069 CA CYS A 482 5107 4353 5516 -668 351 -269 C ATOM 1070 C CYS A 482 -11.366 26.495 -13.542 1.00 42.34 C ANISOU 1070 C CYS A 482 5587 4699 5800 -768 427 -292 C ATOM 1071 O CYS A 482 -11.770 26.349 -14.688 1.00 41.26 O ANISOU 1071 O CYS A 482 5550 4557 5569 -756 383 -234 O ATOM 1072 CB CYS A 482 -12.606 25.157 -11.821 1.00 33.05 C ANISOU 1072 CB CYS A 482 4136 3660 4762 -656 273 -312 C ATOM 1073 SG CYS A 482 -13.559 25.204 -10.242 1.00 32.05 S ANISOU 1073 SG CYS A 482 3879 3559 4739 -573 219 -313 S ATOM 1074 N ILE A 483 -10.074 26.566 -13.247 1.00 43.00 N ANISOU 1074 N ILE A 483 5648 4775 5914 -871 543 -387 N ATOM 1075 CA ILE A 483 -9.050 26.263 -14.246 1.00 44.48 C ANISOU 1075 CA ILE A 483 5898 4961 6040 -981 629 -442 C ATOM 1076 C ILE A 483 -9.062 24.773 -14.570 1.00 43.77 C ANISOU 1076 C ILE A 483 5705 4975 5952 -983 559 -477 C ATOM 1077 O ILE A 483 -8.907 23.920 -13.695 1.00 37.33 O ANISOU 1077 O ILE A 483 4732 4230 5220 -965 517 -536 O ATOM 1078 CB ILE A 483 -7.657 26.695 -13.748 1.00 46.42 C ANISOU 1078 CB ILE A 483 6111 5185 6342 -1090 771 -558 C ATOM 1079 CG1 ILE A 483 -7.637 28.223 -13.541 1.00 41.31 C ANISOU 1079 CG1 ILE A 483 5594 4421 5681 -1105 857 -525 C ATOM 1080 CG2 ILE A 483 -6.568 26.292 -14.755 1.00 41.60 C ANISOU 1080 CG2 ILE A 483 5539 4585 5683 -1212 872 -640 C ATOM 1081 CD1 ILE A 483 -6.459 28.723 -12.678 1.00 50.87 C ANISOU 1081 CD1 ILE A 483 6736 5620 6972 -1198 978 -646 C ATOM 1082 N ILE A 484 -9.302 24.457 -15.829 1.00 35.09 N ANISOU 1082 N ILE A 484 4707 3876 4750 -1001 540 -437 N ATOM 1083 CA ILE A 484 -9.225 23.082 -16.297 1.00 40.32 C ANISOU 1083 CA ILE A 484 5294 4623 5403 -1019 494 -479 C ATOM 1084 C ILE A 484 -7.935 22.851 -17.090 1.00 52.54 C ANISOU 1084 C ILE A 484 6883 6164 6916 -1146 622 -574 C ATOM 1085 O ILE A 484 -7.848 23.177 -18.275 1.00 48.31 O ANISOU 1085 O ILE A 484 6506 5585 6266 -1204 673 -545 O ATOM 1086 CB ILE A 484 -10.419 22.752 -17.187 1.00 42.21 C ANISOU 1086 CB ILE A 484 5605 4883 5549 -958 378 -383 C ATOM 1087 CG1 ILE A 484 -11.721 23.039 -16.435 1.00 37.87 C ANISOU 1087 CG1 ILE A 484 5001 4343 5044 -834 260 -304 C ATOM 1088 CG2 ILE A 484 -10.352 21.300 -17.660 1.00 40.54 C ANISOU 1088 CG2 ILE A 484 5319 4756 5327 -986 337 -433 C ATOM 1089 CD1 ILE A 484 -11.881 22.188 -15.179 1.00 39.80 C ANISOU 1089 CD1 ILE A 484 5057 4659 5406 -799 213 -356 C ATOM 1090 N ASP A 485 -6.934 22.288 -16.437 1.00 44.72 N ANISOU 1090 N ASP A 485 5752 5217 6024 -1189 673 -693 N ATOM 1091 CA ASP A 485 -5.689 21.950 -17.112 1.00 44.17 C ANISOU 1091 CA ASP A 485 5681 5154 5947 -1304 795 -809 C ATOM 1092 C ASP A 485 -5.337 20.500 -16.770 1.00 49.92 C ANISOU 1092 C ASP A 485 6243 5968 6757 -1283 742 -895 C ATOM 1093 O ASP A 485 -6.151 19.806 -16.160 1.00 54.27 O ANISOU 1093 O ASP A 485 6717 6563 7342 -1190 616 -848 O ATOM 1094 CB ASP A 485 -4.586 22.968 -16.750 1.00 47.87 C ANISOU 1094 CB ASP A 485 6158 5571 6460 -1390 939 -893 C ATOM 1095 CG ASP A 485 -4.164 22.902 -15.291 1.00 52.10 C ANISOU 1095 CG ASP A 485 6520 6145 7132 -1350 911 -963 C ATOM 1096 OD1 ASP A 485 -4.545 21.949 -14.578 1.00 49.04 O ANISOU 1096 OD1 ASP A 485 6005 5821 6805 -1265 794 -961 O ATOM 1097 OD2 ASP A 485 -3.416 23.808 -14.858 1.00 53.13 O ANISOU 1097 OD2 ASP A 485 6649 6237 7301 -1412 1012 -1027 O ATOM 1098 N LYS A 486 -4.162 20.018 -17.163 1.00 52.84 N ANISOU 1098 N LYS A 486 6561 6359 7159 -1367 839 -1026 N ATOM 1099 CA LYS A 486 -3.878 18.586 -17.063 1.00 58.87 C ANISOU 1099 CA LYS A 486 7194 7188 7984 -1340 787 -1101 C ATOM 1100 C LYS A 486 -4.006 18.057 -15.634 1.00 58.53 C ANISOU 1100 C LYS A 486 7001 7185 8054 -1241 679 -1112 C ATOM 1101 O LYS A 486 -4.558 16.988 -15.392 1.00 58.40 O ANISOU 1101 O LYS A 486 6931 7205 8055 -1174 576 -1089 O ATOM 1102 CB LYS A 486 -2.478 18.268 -17.593 1.00 63.02 C ANISOU 1102 CB LYS A 486 7667 7726 8550 -1439 918 -1262 C ATOM 1103 CG LYS A 486 -2.183 16.766 -17.673 1.00 71.09 C ANISOU 1103 CG LYS A 486 8576 8804 9632 -1407 871 -1342 C ATOM 1104 CD LYS A 486 -0.860 16.479 -18.389 1.00 79.07 C ANISOU 1104 CD LYS A 486 9541 9824 10678 -1509 1013 -1508 C ATOM 1105 CE LYS A 486 -0.760 15.019 -18.809 1.00 84.88 C ANISOU 1105 CE LYS A 486 10214 10598 11440 -1482 976 -1569 C ATOM 1106 NZ LYS A 486 -0.634 14.085 -17.654 1.00 84.70 N ANISOU 1106 NZ LYS A 486 10032 10609 11543 -1365 856 -1606 N ATOM 1107 N ILE A 487 -3.477 18.803 -14.684 1.00 71.80 N ANISOU 1107 N ILE A 487 8623 8853 9805 -1240 707 -1152 N ATOM 1108 CA ILE A 487 -3.422 18.310 -13.324 1.00 76.78 C ANISOU 1108 CA ILE A 487 9123 9519 10533 -1158 613 -1178 C ATOM 1109 C ILE A 487 -4.728 18.623 -12.577 1.00 70.84 C ANISOU 1109 C ILE A 487 8406 8754 9756 -1077 513 -1046 C ATOM 1110 O ILE A 487 -5.177 17.834 -11.752 1.00 78.26 O ANISOU 1110 O ILE A 487 9279 9722 10734 -1004 411 -1027 O ATOM 1111 CB ILE A 487 -2.148 18.827 -12.601 1.00 89.22 C ANISOU 1111 CB ILE A 487 10598 11101 12201 -1197 680 -1307 C ATOM 1112 CG1 ILE A 487 -2.085 18.282 -11.176 1.00 87.35 C ANISOU 1112 CG1 ILE A 487 10241 10899 12049 -1107 566 -1330 C ATOM 1113 CG2 ILE A 487 -2.059 20.354 -12.650 1.00 92.03 C ANISOU 1113 CG2 ILE A 487 11042 11402 12523 -1266 783 -1286 C ATOM 1114 CD1 ILE A 487 -1.672 16.819 -11.126 1.00 90.32 C ANISOU 1114 CD1 ILE A 487 10522 11317 12479 -1055 495 -1399 C ATOM 1115 N ARG A 488 -5.377 19.731 -12.928 1.00 53.87 N ANISOU 1115 N ARG A 488 6371 6556 7540 -1091 545 -957 N ATOM 1116 CA ARG A 488 -6.614 20.151 -12.243 1.00 49.78 C ANISOU 1116 CA ARG A 488 5878 6024 7011 -1012 462 -845 C ATOM 1117 C ARG A 488 -7.949 19.714 -12.862 1.00 48.49 C ANISOU 1117 C ARG A 488 5773 5874 6779 -962 376 -739 C ATOM 1118 O ARG A 488 -8.989 19.935 -12.236 1.00 39.76 O ANISOU 1118 O ARG A 488 4660 4767 5680 -894 305 -666 O ATOM 1119 CB ARG A 488 -6.674 21.672 -12.173 1.00 40.14 C ANISOU 1119 CB ARG A 488 4747 4735 5768 -1035 533 -806 C ATOM 1120 CG ARG A 488 -5.616 22.347 -11.305 1.00 49.43 C ANISOU 1120 CG ARG A 488 5867 5898 7017 -1080 610 -899 C ATOM 1121 CD ARG A 488 -5.659 23.814 -11.676 1.00 43.95 C ANISOU 1121 CD ARG A 488 5305 5119 6276 -1125 706 -858 C ATOM 1122 NE ARG A 488 -4.766 24.598 -10.894 1.00 58.62 N ANISOU 1122 NE ARG A 488 7123 6956 8194 -1179 788 -944 N ATOM 1123 CZ ARG A 488 -3.642 25.109 -11.354 1.00 64.65 C ANISOU 1123 CZ ARG A 488 7909 7695 8960 -1289 919 -1040 C ATOM 1124 NH1 ARG A 488 -2.876 25.831 -10.542 1.00 61.64 N ANISOU 1124 NH1 ARG A 488 7477 7302 8640 -1340 987 -1128 N ATOM 1125 NH2 ARG A 488 -3.298 24.899 -12.617 1.00 49.67 N ANISOU 1125 NH2 ARG A 488 6087 5787 7000 -1357 988 -1056 N ATOM 1126 N ARG A 489 -7.939 19.145 -14.079 1.00 42.33 N ANISOU 1126 N ARG A 489 5046 5107 5932 -998 385 -740 N ATOM 1127 CA ARG A 489 -9.177 18.800 -14.793 1.00 38.09 C ANISOU 1127 CA ARG A 489 4568 4587 5318 -959 301 -649 C ATOM 1128 C ARG A 489 -10.020 17.834 -13.969 1.00 41.56 C ANISOU 1128 C ARG A 489 4908 5077 5807 -891 194 -632 C ATOM 1129 O ARG A 489 -11.237 17.781 -14.058 1.00 40.49 O ANISOU 1129 O ARG A 489 4784 4959 5641 -842 114 -559 O ATOM 1130 CB ARG A 489 -8.849 18.152 -16.144 1.00 47.80 C ANISOU 1130 CB ARG A 489 5858 5831 6471 -1024 332 -679 C ATOM 1131 CG ARG A 489 -8.137 16.806 -16.032 1.00 48.82 C ANISOU 1131 CG ARG A 489 5886 6005 6657 -1045 336 -779 C ATOM 1132 CD ARG A 489 -7.538 16.360 -17.384 1.00 50.41 C ANISOU 1132 CD ARG A 489 6154 6209 6790 -1129 408 -833 C ATOM 1133 NE ARG A 489 -6.885 15.063 -17.276 1.00 54.70 N ANISOU 1133 NE ARG A 489 6599 6788 7398 -1137 410 -933 N ATOM 1134 CZ ARG A 489 -5.930 14.622 -18.094 0.84 57.33 C ANISOU 1134 CZ ARG A 489 6938 7121 7723 -1212 501 -1031 C ATOM 1135 NH1 ARG A 489 -5.506 15.361 -19.107 1.00 61.71 N ANISOU 1135 NH1 ARG A 489 7603 7646 8197 -1300 607 -1043 N ATOM 1136 NH2 ARG A 489 -5.394 13.433 -17.897 1.00 49.97 N ANISOU 1136 NH2 ARG A 489 5909 6213 6863 -1198 492 -1122 N ATOM 1137 N LYS A 490 -9.334 17.067 -13.152 1.00 40.11 N ANISOU 1137 N LYS A 490 4628 4914 5699 -891 194 -707 N ATOM 1138 CA LYS A 490 -9.947 16.103 -12.262 1.00 49.04 C ANISOU 1138 CA LYS A 490 5683 6077 6874 -841 110 -701 C ATOM 1139 C LYS A 490 -10.638 16.750 -11.033 1.00 47.99 C ANISOU 1139 C LYS A 490 5521 5933 6780 -788 77 -655 C ATOM 1140 O LYS A 490 -11.568 16.186 -10.464 1.00 41.07 O ANISOU 1140 O LYS A 490 4611 5079 5914 -752 12 -624 O ATOM 1141 CB LYS A 490 -8.812 15.213 -11.814 1.00 53.44 C ANISOU 1141 CB LYS A 490 6170 6643 7493 -852 125 -799 C ATOM 1142 CG LYS A 490 -9.203 14.005 -11.089 1.00 67.32 C ANISOU 1142 CG LYS A 490 7878 8418 9280 -813 50 -805 C ATOM 1143 CD LYS A 490 -7.986 13.113 -11.014 1.00 72.78 C ANISOU 1143 CD LYS A 490 8520 9110 10023 -818 62 -905 C ATOM 1144 CE LYS A 490 -8.188 11.974 -10.040 1.00 75.35 C ANISOU 1144 CE LYS A 490 8815 9432 10384 -768 -14 -912 C ATOM 1145 NZ LYS A 490 -6.895 11.263 -9.822 1.00 81.36 N ANISOU 1145 NZ LYS A 490 9522 10183 11207 -749 -15 -1014 N ATOM 1146 N ASN A 491 -10.195 17.943 -10.639 1.00 33.46 N ANISOU 1146 N ASN A 491 3699 4054 4958 -794 132 -657 N ATOM 1147 CA ASN A 491 -10.788 18.644 -9.477 1.00 31.39 C ANISOU 1147 CA ASN A 491 3417 3777 4735 -751 115 -622 C ATOM 1148 C ASN A 491 -12.243 18.976 -9.687 1.00 36.60 C ANISOU 1148 C ASN A 491 4102 4440 5366 -703 65 -537 C ATOM 1149 O ASN A 491 -13.046 18.811 -8.778 1.00 35.69 O ANISOU 1149 O ASN A 491 3940 4338 5283 -666 25 -520 O ATOM 1150 CB ASN A 491 -10.100 19.980 -9.211 1.00 30.58 C ANISOU 1150 CB ASN A 491 3346 3624 4648 -774 195 -639 C ATOM 1151 CG ASN A 491 -8.691 19.823 -8.728 1.00 37.21 C ANISOU 1151 CG ASN A 491 4134 4469 5536 -817 241 -740 C ATOM 1152 OD1 ASN A 491 -8.095 20.779 -8.181 0.73 35.67 O ANISOU 1152 OD1 ASN A 491 3939 4244 5370 -841 299 -775 O ATOM 1153 ND2 ASN A 491 -8.139 18.640 -8.905 1.00 34.97 N ANISOU 1153 ND2 ASN A 491 3799 4222 5266 -825 213 -797 N ATOM 1154 N CYS A 492 -12.598 19.467 -10.873 1.00 33.76 N ANISOU 1154 N CYS A 492 3818 4065 4943 -702 67 -488 N ATOM 1155 CA CYS A 492 -13.958 19.980 -11.026 1.00 27.71 C ANISOU 1155 CA CYS A 492 3069 3300 4161 -638 9 -412 C ATOM 1156 C CYS A 492 -14.675 19.464 -12.265 1.00 28.08 C ANISOU 1156 C CYS A 492 3150 3383 4136 -630 -57 -375 C ATOM 1157 O CYS A 492 -14.636 20.111 -13.318 1.00 31.33 O ANISOU 1157 O CYS A 492 3663 3763 4477 -631 -50 -334 O ATOM 1158 CB CYS A 492 -13.984 21.519 -10.989 1.00 28.28 C ANISOU 1158 CB CYS A 492 3215 3299 4230 -611 54 -370 C ATOM 1159 SG CYS A 492 -15.696 22.061 -10.832 1.00 30.10 S ANISOU 1159 SG CYS A 492 3426 3534 4476 -507 -31 -297 S ATOM 1160 N PRO A 493 -15.347 18.308 -12.145 1.00 36.57 N ANISOU 1160 N PRO A 493 4151 4521 5222 -626 -120 -390 N ATOM 1161 CA PRO A 493 -16.045 17.764 -13.311 1.00 36.52 C ANISOU 1161 CA PRO A 493 4168 4559 5147 -626 -188 -366 C ATOM 1162 C PRO A 493 -17.134 18.694 -13.800 1.00 44.79 C ANISOU 1162 C PRO A 493 5250 5602 6164 -554 -253 -296 C ATOM 1163 O PRO A 493 -17.419 18.711 -14.991 1.00 35.81 O ANISOU 1163 O PRO A 493 4184 4479 4943 -551 -301 -264 O ATOM 1164 CB PRO A 493 -16.662 16.427 -12.814 1.00 32.97 C ANISOU 1164 CB PRO A 493 3622 4173 4732 -639 -234 -405 C ATOM 1165 CG PRO A 493 -16.250 16.256 -11.365 1.00 35.46 C ANISOU 1165 CG PRO A 493 3879 4468 5126 -643 -191 -441 C ATOM 1166 CD PRO A 493 -15.356 17.403 -10.963 1.00 35.60 C ANISOU 1166 CD PRO A 493 3937 4424 5164 -636 -124 -437 C ATOM 1167 N ALA A 494 -17.746 19.460 -12.914 1.00 36.29 N ANISOU 1167 N ALA A 494 4131 4507 5152 -491 -260 -276 N ATOM 1168 CA ALA A 494 -18.775 20.405 -13.348 1.00 30.75 C ANISOU 1168 CA ALA A 494 3456 3792 4434 -402 -329 -215 C ATOM 1169 C ALA A 494 -18.183 21.383 -14.357 1.00 42.51 C ANISOU 1169 C ALA A 494 5107 5209 5838 -399 -305 -160 C ATOM 1170 O ALA A 494 -18.788 21.655 -15.398 1.00 40.68 O ANISOU 1170 O ALA A 494 4946 4980 5531 -353 -385 -108 O ATOM 1171 CB ALA A 494 -19.340 21.208 -12.153 1.00 35.73 C ANISOU 1171 CB ALA A 494 4022 4395 5158 -338 -313 -212 C ATOM 1172 N CYS A 495 -17.025 21.953 -14.027 1.00 30.74 N ANISOU 1172 N CYS A 495 3678 3647 4355 -448 -196 -174 N ATOM 1173 CA CYS A 495 -16.417 22.979 -14.891 1.00 37.29 C ANISOU 1173 CA CYS A 495 4676 4390 5103 -461 -146 -129 C ATOM 1174 C CYS A 495 -15.763 22.324 -16.118 1.00 45.84 C ANISOU 1174 C CYS A 495 5844 5491 6083 -544 -130 -142 C ATOM 1175 O CYS A 495 -15.732 22.885 -17.191 0.90 41.50 O ANISOU 1175 O CYS A 495 5445 4894 5429 -545 -136 -89 O ATOM 1176 CB CYS A 495 -15.388 23.801 -14.103 1.00 30.58 C ANISOU 1176 CB CYS A 495 3854 3464 4301 -503 -22 -158 C ATOM 1177 SG CYS A 495 -16.167 25.065 -13.045 1.00 32.52 S ANISOU 1177 SG CYS A 495 4081 3647 4629 -402 -27 -121 S ATOM 1178 N ARG A 496 -15.242 21.124 -15.956 1.00 39.83 N ANISOU 1178 N ARG A 496 4995 4792 5347 -611 -107 -213 N ATOM 1179 CA ARG A 496 -14.631 20.436 -17.069 1.00 41.59 C ANISOU 1179 CA ARG A 496 5285 5034 5483 -691 -83 -240 C ATOM 1180 C ARG A 496 -15.705 20.124 -18.113 1.00 51.99 C ANISOU 1180 C ARG A 496 6648 6397 6710 -652 -202 -187 C ATOM 1181 O ARG A 496 -15.509 20.262 -19.321 1.00 47.34 O ANISOU 1181 O ARG A 496 6196 5788 6003 -689 -200 -161 O ATOM 1182 CB ARG A 496 -13.987 19.148 -16.592 1.00 36.44 C ANISOU 1182 CB ARG A 496 4517 4437 4891 -750 -50 -330 C ATOM 1183 CG ARG A 496 -13.361 18.323 -17.740 1.00 38.13 C ANISOU 1183 CG ARG A 496 4788 4673 5028 -834 -18 -373 C ATOM 1184 CD ARG A 496 -12.830 17.025 -17.212 1.00 43.46 C ANISOU 1184 CD ARG A 496 5346 5394 5774 -870 0 -460 C ATOM 1185 NE ARG A 496 -11.812 16.443 -18.082 1.00 50.51 N ANISOU 1185 NE ARG A 496 6283 6285 6623 -957 77 -529 N ATOM 1186 CZ ARG A 496 -11.209 15.294 -17.816 1.00 41.91 C ANISOU 1186 CZ ARG A 496 5111 5224 5590 -987 99 -612 C ATOM 1187 NH1 ARG A 496 -11.538 14.619 -16.714 1.00 37.59 N ANISOU 1187 NH1 ARG A 496 4451 4701 5130 -940 46 -627 N ATOM 1188 NH2 ARG A 496 -10.291 14.823 -18.631 1.00 40.25 N ANISOU 1188 NH2 ARG A 496 4936 5010 5349 -1062 175 -684 N ATOM 1189 N TYR A 497 -16.860 19.723 -17.622 1.00 39.65 N ANISOU 1189 N TYR A 497 4968 4896 5200 -582 -305 -178 N ATOM 1190 CA TYR A 497 -17.939 19.311 -18.478 1.00 46.32 C ANISOU 1190 CA TYR A 497 5816 5805 5979 -544 -431 -148 C ATOM 1191 C TYR A 497 -18.509 20.547 -19.163 1.00 59.07 C ANISOU 1191 C TYR A 497 7560 7365 7517 -460 -498 -58 C ATOM 1192 O TYR A 497 -18.931 20.482 -20.328 1.00 53.01 O ANISOU 1192 O TYR A 497 6888 6618 6635 -450 -582 -21 O ATOM 1193 CB TYR A 497 -18.991 18.589 -17.654 1.00 40.39 C ANISOU 1193 CB TYR A 497 4890 5134 5321 -501 -505 -181 C ATOM 1194 CG TYR A 497 -20.235 18.218 -18.416 1.00 56.06 C ANISOU 1194 CG TYR A 497 6845 7197 7256 -457 -644 -166 C ATOM 1195 CD1 TYR A 497 -20.161 17.465 -19.586 1.00 55.28 C ANISOU 1195 CD1 TYR A 497 6810 7143 7052 -517 -680 -178 C ATOM 1196 CD2 TYR A 497 -21.488 18.601 -17.958 1.00 60.76 C ANISOU 1196 CD2 TYR A 497 7341 7830 7917 -358 -738 -152 C ATOM 1197 CE1 TYR A 497 -21.296 17.115 -20.283 1.00 59.21 C ANISOU 1197 CE1 TYR A 497 7274 7721 7501 -480 -816 -174 C ATOM 1198 CE2 TYR A 497 -22.634 18.251 -18.649 1.00 75.91 C ANISOU 1198 CE2 TYR A 497 9212 9832 9800 -316 -874 -154 C ATOM 1199 CZ TYR A 497 -22.529 17.512 -19.818 1.00 73.77 C ANISOU 1199 CZ TYR A 497 9008 9607 9415 -378 -917 -163 C ATOM 1200 OH TYR A 497 -23.663 17.160 -20.510 1.00 74.21 O ANISOU 1200 OH TYR A 497 9012 9755 9431 -340 -1061 -174 O ATOM 1201 N ARG A 498 -18.498 21.672 -18.445 1.00 43.52 N ANISOU 1201 N ARG A 498 5608 5322 5607 -399 -464 -24 N ATOM 1202 CA ARG A 498 -18.917 22.956 -19.008 1.00 45.86 C ANISOU 1202 CA ARG A 498 6051 5538 5838 -311 -514 66 C ATOM 1203 C ARG A 498 -17.950 23.368 -20.112 1.00 52.78 C ANISOU 1203 C ARG A 498 7145 6335 6574 -390 -440 98 C ATOM 1204 O ARG A 498 -18.365 23.848 -21.154 1.00 45.32 O ANISOU 1204 O ARG A 498 6354 5358 5508 -347 -519 169 O ATOM 1205 CB ARG A 498 -18.978 24.078 -17.951 1.00 43.30 C ANISOU 1205 CB ARG A 498 5708 5134 5611 -242 -467 86 C ATOM 1206 CG ARG A 498 -19.391 25.448 -18.547 1.00 54.13 C ANISOU 1206 CG ARG A 498 7253 6400 6914 -142 -517 182 C ATOM 1207 CD ARG A 498 -18.846 26.633 -17.720 1.00 73.21 C ANISOU 1207 CD ARG A 498 9726 8699 9393 -131 -401 194 C ATOM 1208 NE ARG A 498 -18.685 26.201 -16.350 1.00 66.15 N ANISOU 1208 NE ARG A 498 8643 7853 8639 -161 -337 116 N ATOM 1209 CZ ARG A 498 -19.712 25.894 -15.563 1.00 77.23 C ANISOU 1209 CZ ARG A 498 9874 9326 10145 -83 -413 91 C ATOM 1210 NH1 ARG A 498 -20.951 26.038 -16.042 1.00 73.26 N ANISOU 1210 NH1 ARG A 498 9350 8855 9632 36 -556 133 N ATOM 1211 NH2 ARG A 498 -19.505 25.441 -14.309 1.00 60.06 N ANISOU 1211 NH2 ARG A 498 7551 7191 8079 -125 -346 20 N ATOM 1212 N LYS A 499 -16.657 23.196 -19.878 1.00 42.92 N ANISOU 1212 N LYS A 499 5913 5056 5339 -507 -288 40 N ATOM 1213 CA LYS A 499 -15.674 23.602 -20.857 1.00 46.24 C ANISOU 1213 CA LYS A 499 6532 5401 5638 -602 -188 51 C ATOM 1214 C LYS A 499 -15.811 22.705 -22.096 1.00 61.05 C ANISOU 1214 C LYS A 499 8469 7338 7389 -653 -246 46 C ATOM 1215 O LYS A 499 -15.613 23.169 -23.221 1.00 51.53 O ANISOU 1215 O LYS A 499 7470 6074 6034 -687 -235 95 O ATOM 1216 CB LYS A 499 -14.267 23.528 -20.267 1.00 38.73 C ANISOU 1216 CB LYS A 499 5544 4421 4752 -717 -14 -37 C ATOM 1217 CG LYS A 499 -13.242 24.405 -20.955 1.00 56.05 C ANISOU 1217 CG LYS A 499 7940 6506 6851 -811 125 -31 C ATOM 1218 CD LYS A 499 -11.849 24.224 -20.364 1.00 57.06 C ANISOU 1218 CD LYS A 499 7993 6628 7060 -927 290 -144 C ATOM 1219 CE LYS A 499 -10.831 25.163 -21.033 0.50 57.50 C ANISOU 1219 CE LYS A 499 8248 6573 7026 -1038 448 -153 C ATOM 1220 NZ LYS A 499 -9.433 25.004 -20.506 1.00 53.09 N ANISOU 1220 NZ LYS A 499 7599 6019 6554 -1157 611 -283 N ATOM 1221 N CYS A 500 -16.178 21.438 -21.887 1.00 62.40 N ANISOU 1221 N CYS A 500 8474 7622 7613 -662 -305 -12 N ATOM 1222 CA CYS A 500 -16.361 20.491 -22.996 1.00 60.32 C ANISOU 1222 CA CYS A 500 8251 7425 7241 -714 -360 -29 C ATOM 1223 C CYS A 500 -17.468 21.008 -23.890 1.00 66.94 C ANISOU 1223 C CYS A 500 9206 8265 7962 -623 -517 64 C ATOM 1224 O CYS A 500 -17.302 21.121 -25.106 1.00 56.68 O ANISOU 1224 O CYS A 500 8093 6941 6503 -669 -527 97 O ATOM 1225 CB CYS A 500 -16.754 19.091 -22.500 1.00 48.54 C ANISOU 1225 CB CYS A 500 6558 6047 5839 -725 -407 -104 C ATOM 1226 SG CYS A 500 -15.393 18.090 -21.832 0.89 40.52 S ANISOU 1226 SG CYS A 500 5434 5041 4921 -839 -251 -223 S ATOM 1227 N LEU A 501 -18.603 21.322 -23.271 1.00 57.79 N ANISOU 1227 N LEU A 501 7938 7136 6883 -492 -641 100 N ATOM 1228 CA LEU A 501 -19.764 21.776 -24.011 1.00 64.97 C ANISOU 1228 CA LEU A 501 8919 8060 7705 -379 -818 177 C ATOM 1229 C LEU A 501 -19.455 23.080 -24.739 1.00 69.73 C ANISOU 1229 C LEU A 501 9784 8531 8179 -350 -804 274 C ATOM 1230 O LEU A 501 -19.861 23.270 -25.877 1.00 76.01 O ANISOU 1230 O LEU A 501 10743 9317 8819 -323 -909 335 O ATOM 1231 CB LEU A 501 -20.957 21.940 -23.075 1.00 58.26 C ANISOU 1231 CB LEU A 501 7880 7262 6994 -244 -931 177 C ATOM 1232 CG LEU A 501 -21.557 20.626 -22.583 1.00 60.83 C ANISOU 1232 CG LEU A 501 7975 7724 7415 -269 -977 89 C ATOM 1233 CD1 LEU A 501 -22.668 20.902 -21.583 1.00 60.46 C ANISOU 1233 CD1 LEU A 501 7745 7716 7510 -149 -1058 79 C ATOM 1234 CD2 LEU A 501 -22.063 19.762 -23.756 1.00 61.96 C ANISOU 1234 CD2 LEU A 501 8145 7960 7439 -301 -1092 74 C ATOM 1235 N GLN A 502 -18.702 23.953 -24.088 1.00 60.84 N ANISOU 1235 N GLN A 502 8711 7298 7109 -365 -669 285 N ATOM 1236 CA GLN A 502 -18.313 25.233 -24.672 1.00 65.97 C ANISOU 1236 CA GLN A 502 9623 7799 7642 -354 -624 373 C ATOM 1237 C GLN A 502 -17.297 25.102 -25.801 1.00 69.51 C ANISOU 1237 C GLN A 502 10288 8200 7923 -504 -512 367 C ATOM 1238 O GLN A 502 -17.175 25.993 -26.647 1.00 68.90 O ANISOU 1238 O GLN A 502 10474 8010 7694 -502 -508 450 O ATOM 1239 CB GLN A 502 -17.728 26.149 -23.601 1.00 54.04 C ANISOU 1239 CB GLN A 502 8096 6190 6246 -351 -490 367 C ATOM 1240 CG GLN A 502 -18.738 26.570 -22.536 1.00 78.12 C ANISOU 1240 CG GLN A 502 10981 9255 9445 -197 -585 383 C ATOM 1241 CD GLN A 502 -18.126 27.479 -21.475 1.00 85.31 C ANISOU 1241 CD GLN A 502 11886 10066 10461 -204 -445 371 C ATOM 1242 OE1 GLN A 502 -16.893 27.604 -21.375 1.00 77.12 O ANISOU 1242 OE1 GLN A 502 10915 8975 9414 -337 -273 328 O ATOM 1243 NE2 GLN A 502 -18.986 28.120 -20.678 1.00 72.90 N ANISOU 1243 NE2 GLN A 502 10228 8473 8996 -66 -516 397 N ATOM 1244 N ALA A 503 -16.539 24.018 -25.813 1.00 58.19 N ANISOU 1244 N ALA A 503 8756 6839 6513 -638 -412 267 N ATOM 1245 CA ALA A 503 -15.563 23.862 -26.877 1.00 62.98 C ANISOU 1245 CA ALA A 503 9555 7405 6970 -789 -290 245 C ATOM 1246 C ALA A 503 -16.253 23.259 -28.097 1.00 70.22 C ANISOU 1246 C ALA A 503 10567 8388 7727 -784 -431 276 C ATOM 1247 O ALA A 503 -15.656 23.158 -29.160 1.00 68.81 O ANISOU 1247 O ALA A 503 10581 8175 7389 -899 -359 271 O ATOM 1248 CB ALA A 503 -14.411 23.005 -26.436 1.00 51.52 C ANISOU 1248 CB ALA A 503 7966 5996 5612 -928 -121 116 C ATOM 1249 N GLY A 504 -17.508 22.857 -27.927 1.00 65.72 N ANISOU 1249 N GLY A 504 9856 7914 7201 -657 -628 299 N ATOM 1250 CA GLY A 504 -18.306 22.341 -29.017 1.00 63.13 C ANISOU 1250 CA GLY A 504 9599 7660 6729 -635 -790 326 C ATOM 1251 C GLY A 504 -18.510 20.841 -28.972 0.92 67.53 C ANISOU 1251 C GLY A 504 9953 8363 7343 -695 -819 225 C ATOM 1252 O GLY A 504 -19.029 20.269 -29.924 1.00 60.89 O ANISOU 1252 O GLY A 504 9167 7591 6377 -709 -931 225 O ATOM 1253 N MET A 505 -18.119 20.182 -27.883 1.00 53.93 N ANISOU 1253 N MET A 505 8007 6685 5801 -731 -723 137 N ATOM 1254 CA MET A 505 -18.234 18.725 -27.845 1.00 58.91 C ANISOU 1254 CA MET A 505 8469 7434 6480 -796 -734 39 C ATOM 1255 C MET A 505 -19.693 18.327 -27.914 1.00 62.72 C ANISOU 1255 C MET A 505 8834 8025 6973 -693 -943 53 C ATOM 1256 O MET A 505 -20.572 18.986 -27.366 1.00 62.93 O ANISOU 1256 O MET A 505 8789 8054 7070 -558 -1054 103 O ATOM 1257 CB MET A 505 -17.539 18.114 -26.621 1.00 54.47 C ANISOU 1257 CB MET A 505 7709 6885 6103 -842 -602 -50 C ATOM 1258 CG MET A 505 -16.036 18.396 -26.591 1.00 60.00 C ANISOU 1258 CG MET A 505 8498 7497 6803 -952 -397 -90 C ATOM 1259 SD MET A 505 -15.128 17.452 -25.341 1.00 49.17 S ANISOU 1259 SD MET A 505 6903 6153 5627 -1009 -265 -211 S ATOM 1260 CE MET A 505 -15.454 15.784 -25.914 1.00 48.38 C ANISOU 1260 CE MET A 505 6722 6161 5500 -1072 -316 -290 C ATOM 1261 N ASN A 506 -19.942 17.231 -28.606 1.00 56.38 N ANISOU 1261 N ASN A 506 8006 7314 6103 -762 -991 -5 N ATOM 1262 CA ASN A 506 -21.285 16.865 -28.987 1.00 69.48 C ANISOU 1262 CA ASN A 506 9589 9081 7730 -688 -1195 -1 C ATOM 1263 C ASN A 506 -21.289 15.406 -29.393 1.00 73.51 C ANISOU 1263 C ASN A 506 10020 9690 8220 -802 -1183 -101 C ATOM 1264 O ASN A 506 -20.384 14.941 -30.086 1.00 62.51 O ANISOU 1264 O ASN A 506 8748 8271 6733 -928 -1071 -138 O ATOM 1265 CB ASN A 506 -21.740 17.783 -30.121 1.00 89.73 C ANISOU 1265 CB ASN A 506 12378 11609 10105 -618 -1332 100 C ATOM 1266 CG ASN A 506 -22.947 17.267 -30.842 1.00103.71 C ANISOU 1266 CG ASN A 506 14104 13502 11798 -571 -1544 88 C ATOM 1267 OD1 ASN A 506 -23.922 16.839 -30.226 1.00107.63 O ANISOU 1267 OD1 ASN A 506 14375 14099 12422 -502 -1648 41 O ATOM 1268 ND2 ASN A 506 -22.901 17.324 -32.166 1.00112.52 N ANISOU 1268 ND2 ASN A 506 15441 14613 12699 -613 -1608 124 N ATOM 1269 N LEU A 507 -22.309 14.688 -28.950 1.00 93.46 N ANISOU 1269 N LEU A 507 12343 12326 10840 -764 -1290 -154 N ATOM 1270 CA LEU A 507 -22.310 13.241 -29.020 1.00104.74 C ANISOU 1270 CA LEU A 507 13666 13837 12295 -874 -1254 -262 C ATOM 1271 C LEU A 507 -22.669 12.738 -30.416 1.00118.72 C ANISOU 1271 C LEU A 507 15551 15675 13882 -935 -1353 -280 C ATOM 1272 O LEU A 507 -22.141 11.727 -30.883 1.00119.37 O ANISOU 1272 O LEU A 507 15659 15776 13918 -1064 -1267 -356 O ATOM 1273 CB LEU A 507 -23.304 12.700 -28.005 1.00 96.09 C ANISOU 1273 CB LEU A 507 12321 12827 11363 -824 -1319 -317 C ATOM 1274 CG LEU A 507 -22.812 11.506 -27.201 1.00 92.10 C ANISOU 1274 CG LEU A 507 11687 12329 10979 -921 -1183 -412 C ATOM 1275 CD1 LEU A 507 -21.502 11.855 -26.506 1.00 83.62 C ANISOU 1275 CD1 LEU A 507 10658 11142 9973 -942 -1009 -396 C ATOM 1276 CD2 LEU A 507 -23.878 11.092 -26.194 1.00 93.69 C ANISOU 1276 CD2 LEU A 507 11666 12604 11326 -876 -1243 -460 C ATOM 1277 N GLU A 508 -23.564 13.453 -31.084 1.00128.54 N ANISOU 1277 N GLU A 508 16868 16951 15019 -838 -1538 -212 N ATOM 1278 CA GLU A 508 -24.084 13.007 -32.365 1.00141.74 C ANISOU 1278 CA GLU A 508 18638 18705 16514 -880 -1668 -230 C ATOM 1279 C GLU A 508 -23.409 13.757 -33.502 1.00141.23 C ANISOU 1279 C GLU A 508 18877 18550 16234 -910 -1651 -147 C ATOM 1280 O GLU A 508 -24.041 14.094 -34.497 1.00149.50 O ANISOU 1280 O GLU A 508 20057 19633 17113 -866 -1821 -99 O ATOM 1281 CB GLU A 508 -25.596 13.218 -32.405 1.00153.90 C ANISOU 1281 CB GLU A 508 20051 20354 18070 -750 -1909 -223 C ATOM 1282 CG GLU A 508 -26.329 12.571 -31.237 1.00162.91 C ANISOU 1282 CG GLU A 508 20894 21579 19426 -728 -1914 -310 C ATOM 1283 CD GLU A 508 -26.922 11.221 -31.589 1.00171.94 C ANISOU 1283 CD GLU A 508 21916 22852 20560 -830 -1961 -430 C ATOM 1284 OE1 GLU A 508 -26.421 10.574 -32.531 1.00173.56 O ANISOU 1284 OE1 GLU A 508 22256 23064 20624 -952 -1920 -462 O ATOM 1285 OE2 GLU A 508 -27.894 10.806 -30.922 1.00176.29 O ANISOU 1285 OE2 GLU A 508 22240 23498 21246 -798 -2029 -501 O ATOM 1286 N ALA A 509 -22.116 14.012 -33.343 1.00135.85 N ANISOU 1286 N ALA A 509 18307 17753 15556 -988 -1445 -136 N ATOM 1287 CA ALA A 509 -21.343 14.717 -34.356 1.00134.75 C ANISOU 1287 CA ALA A 509 18465 17515 15218 -1043 -1383 -69 C ATOM 1288 C ALA A 509 -20.341 13.782 -35.015 1.00146.21 C ANISOU 1288 C ALA A 509 20002 18961 16590 -1230 -1213 -159 C ATOM 1289 O ALA A 509 -19.212 13.643 -34.543 1.00148.72 O ANISOU 1289 O ALA A 509 20302 19209 16995 -1310 -1006 -206 O ATOM 1290 CB ALA A 509 -20.617 15.884 -33.734 1.00123.94 C ANISOU 1290 CB ALA A 509 17174 16010 13907 -996 -1266 6 C ATOM 1291 N ARG A 510 -20.752 13.142 -36.105 1.00149.99 N ANISOU 1291 N ARG A 510 20568 19515 16905 -1296 -1304 -193 N ATOM 1292 CA ARG A 510 -19.861 12.259 -36.846 1.00150.48 C ANISOU 1292 CA ARG A 510 20728 19572 16877 -1475 -1146 -284 C ATOM 1293 C ARG A 510 -20.459 11.926 -38.207 1.00156.21 C ANISOU 1293 C ARG A 510 21614 20368 17369 -1527 -1286 -287 C ATOM 1294 O ARG A 510 -21.492 12.474 -38.590 1.00159.32 O ANISOU 1294 O ARG A 510 22060 20809 17667 -1417 -1509 -210 O ATOM 1295 CB ARG A 510 -19.613 10.979 -36.048 1.00142.24 C ANISOU 1295 CB ARG A 510 19439 18580 16026 -1537 -1040 -412 C ATOM 1296 CG ARG A 510 -18.150 10.557 -35.960 1.00132.46 C ANISOU 1296 CG ARG A 510 18232 17262 14836 -1666 -783 -492 C ATOM 1297 CD ARG A 510 -17.749 9.589 -37.067 1.00119.00 C ANISOU 1297 CD ARG A 510 16638 15585 12993 -1824 -708 -588 C ATOM 1298 NE ARG A 510 -16.852 8.550 -36.559 1.00105.90 N ANISOU 1298 NE ARG A 510 14844 13907 11484 -1909 -523 -713 N ATOM 1299 CZ ARG A 510 -17.245 7.508 -35.823 1.00 94.53 C ANISOU 1299 CZ ARG A 510 13189 12527 10202 -1893 -546 -786 C ATOM 1300 NH1 ARG A 510 -18.529 7.352 -35.505 1.00 86.90 N ANISOU 1300 NH1 ARG A 510 12101 11650 9268 -1810 -733 -758 N ATOM 1301 NH2 ARG A 510 -16.353 6.616 -35.399 1.00 81.97 N ANISOU 1301 NH2 ARG A 510 11505 10901 8738 -1960 -379 -893 N TER 1302 ARG A 510 ATOM 1303 N SER B 437 -22.441 14.116 18.882 1.00166.05 N ANISOU 1303 N SER B 437 18315 24140 20639 537 1196 3339 N ATOM 1304 CA SER B 437 -23.383 14.358 17.795 1.00166.00 C ANISOU 1304 CA SER B 437 18141 24218 20712 543 1190 3514 C ATOM 1305 C SER B 437 -23.039 15.649 17.051 1.00151.14 C ANISOU 1305 C SER B 437 16351 22162 18913 755 1304 3317 C ATOM 1306 O SER B 437 -23.930 16.373 16.602 1.00152.87 O ANISOU 1306 O SER B 437 16415 22508 19160 891 1410 3434 O ATOM 1307 CB SER B 437 -24.801 14.417 18.335 1.00172.44 C ANISOU 1307 CB SER B 437 18674 25412 21433 607 1310 3806 C ATOM 1308 N HIS B 438 -21.744 15.922 16.914 1.00109.91 N ANISOU 1308 N HIS B 438 11374 16654 13733 774 1270 3032 N ATOM 1309 CA HIS B 438 -21.273 17.169 16.309 1.00100.12 C ANISOU 1309 CA HIS B 438 10250 15236 12554 960 1361 2828 C ATOM 1310 C HIS B 438 -20.847 17.036 14.838 1.00 79.35 C ANISOU 1310 C HIS B 438 7690 12394 10067 828 1208 2772 C ATOM 1311 O HIS B 438 -20.872 15.954 14.256 1.00 67.28 O ANISOU 1311 O HIS B 438 6142 10833 8590 596 1031 2877 O ATOM 1312 CB HIS B 438 -20.108 17.737 17.122 1.00111.25 C ANISOU 1312 CB HIS B 438 11891 16481 13900 1078 1433 2556 C ATOM 1313 CG HIS B 438 -20.508 18.816 18.076 1.00129.96 C ANISOU 1313 CG HIS B 438 14256 18973 16150 1347 1659 2516 C ATOM 1314 ND1 HIS B 438 -20.182 18.786 19.415 1.00140.32 N ANISOU 1314 ND1 HIS B 438 15655 20337 17324 1398 1742 2449 N ATOM 1315 CD2 HIS B 438 -21.210 19.957 17.885 1.00142.92 C ANISOU 1315 CD2 HIS B 438 15830 20688 17785 1584 1817 2531 C ATOM 1316 CE1 HIS B 438 -20.664 19.864 20.006 1.00151.33 C ANISOU 1316 CE1 HIS B 438 17049 21829 18620 1659 1950 2416 C ATOM 1317 NE2 HIS B 438 -21.293 20.590 19.100 1.00152.63 N ANISOU 1317 NE2 HIS B 438 17118 22006 18866 1787 2000 2463 N ATOM 1318 N MET B 439 -20.450 18.144 14.235 1.00 94.20 N ANISOU 1318 N MET B 439 9665 14125 12001 970 1271 2605 N ATOM 1319 CA MET B 439 -20.078 18.106 12.831 1.00 90.70 C ANISOU 1319 CA MET B 439 9282 13499 11680 848 1140 2552 C ATOM 1320 C MET B 439 -18.576 18.206 12.668 1.00 66.63 C ANISOU 1320 C MET B 439 6473 10187 8655 820 1078 2275 C ATOM 1321 O MET B 439 -17.907 18.913 13.427 1.00 46.43 O ANISOU 1321 O MET B 439 4041 7567 6035 969 1173 2103 O ATOM 1322 CB MET B 439 -20.745 19.243 12.075 1.00 91.76 C ANISOU 1322 CB MET B 439 9333 13658 11871 991 1223 2590 C ATOM 1323 CG MET B 439 -22.246 19.107 11.949 1.00 96.63 C ANISOU 1323 CG MET B 439 9688 14532 12497 993 1260 2896 C ATOM 1324 SD MET B 439 -22.950 20.703 11.514 1.00123.93 S ANISOU 1324 SD MET B 439 13059 18027 16001 1259 1412 2906 S ATOM 1325 CE MET B 439 -21.738 21.271 10.317 1.00 73.82 C ANISOU 1325 CE MET B 439 6948 11349 9752 1192 1300 2641 C ATOM 1326 N CYS B 440 -18.051 17.484 11.683 1.00 69.45 N ANISOU 1326 N CYS B 440 6897 10397 9095 628 918 2242 N ATOM 1327 CA CYS B 440 -16.653 17.613 11.307 1.00 67.13 C ANISOU 1327 CA CYS B 440 6802 9867 8837 602 860 1996 C ATOM 1328 C CYS B 440 -16.326 19.077 11.096 1.00 64.23 C ANISOU 1328 C CYS B 440 6510 9425 8471 782 962 1843 C ATOM 1329 O CYS B 440 -16.993 19.762 10.330 1.00 57.69 O ANISOU 1329 O CYS B 440 5606 8626 7688 828 989 1906 O ATOM 1330 CB CYS B 440 -16.370 16.847 10.027 1.00 67.66 C ANISOU 1330 CB CYS B 440 6908 9807 8994 403 701 1997 C ATOM 1331 SG CYS B 440 -14.698 17.125 9.406 1.00 45.98 S ANISOU 1331 SG CYS B 440 4375 6805 6292 390 650 1706 S ATOM 1332 N LEU B 441 -15.304 19.565 11.782 1.00 54.69 N ANISOU 1332 N LEU B 441 5456 8113 7209 873 1005 1654 N ATOM 1333 CA LEU B 441 -14.933 20.963 11.659 1.00 51.93 C ANISOU 1333 CA LEU B 441 5210 7679 6842 1033 1080 1510 C ATOM 1334 C LEU B 441 -14.399 21.283 10.267 1.00 56.97 C ANISOU 1334 C LEU B 441 5905 8170 7570 947 987 1419 C ATOM 1335 O LEU B 441 -14.454 22.412 9.851 1.00 52.33 O ANISOU 1335 O LEU B 441 5355 7538 6988 1049 1024 1361 O ATOM 1336 CB LEU B 441 -13.862 21.325 12.685 1.00 42.67 C ANISOU 1336 CB LEU B 441 4215 6417 5582 1109 1116 1342 C ATOM 1337 CG LEU B 441 -14.383 21.642 14.099 1.00 70.97 C ANISOU 1337 CG LEU B 441 7793 10129 9043 1264 1255 1386 C ATOM 1338 CD1 LEU B 441 -13.417 22.597 14.768 1.00 71.07 C ANISOU 1338 CD1 LEU B 441 8023 10014 8967 1374 1298 1201 C ATOM 1339 CD2 LEU B 441 -15.786 22.235 14.082 1.00 74.91 C ANISOU 1339 CD2 LEU B 441 8140 10795 9526 1416 1376 1530 C ATOM 1340 N VAL B 442 -13.876 20.285 9.565 1.00 55.74 N ANISOU 1340 N VAL B 442 5765 7937 7476 760 863 1404 N ATOM 1341 CA VAL B 442 -13.294 20.493 8.241 1.00 52.26 C ANISOU 1341 CA VAL B 442 5384 7365 7106 664 778 1309 C ATOM 1342 C VAL B 442 -14.321 20.467 7.095 1.00 60.50 C ANISOU 1342 C VAL B 442 6308 8458 8220 579 738 1455 C ATOM 1343 O VAL B 442 -14.267 21.307 6.184 1.00 54.29 O ANISOU 1343 O VAL B 442 5544 7611 7471 581 724 1405 O ATOM 1344 CB VAL B 442 -12.217 19.426 7.978 1.00 37.52 C ANISOU 1344 CB VAL B 442 3602 5387 5267 518 674 1215 C ATOM 1345 CG1 VAL B 442 -11.650 19.522 6.514 1.00 46.35 C ANISOU 1345 CG1 VAL B 442 4775 6389 6449 405 592 1123 C ATOM 1346 CG2 VAL B 442 -11.083 19.562 8.997 0.63 27.90 C ANISOU 1346 CG2 VAL B 442 2503 4106 3992 589 699 1072 C ATOM 1347 N CYS B 443 -15.237 19.500 7.120 1.00 43.45 N ANISOU 1347 N CYS B 443 4027 6408 6075 483 704 1647 N ATOM 1348 CA CYS B 443 -16.144 19.286 5.997 1.00 57.12 C ANISOU 1348 CA CYS B 443 5656 8176 7870 354 637 1808 C ATOM 1349 C CYS B 443 -17.611 19.267 6.416 1.00 68.12 C ANISOU 1349 C CYS B 443 6855 9773 9254 400 692 2062 C ATOM 1350 O CYS B 443 -18.494 19.090 5.576 1.00 60.03 O ANISOU 1350 O CYS B 443 5725 8804 8280 288 633 2240 O ATOM 1351 CB CYS B 443 -15.817 17.976 5.283 1.00 54.70 C ANISOU 1351 CB CYS B 443 5407 7785 7593 131 495 1823 C ATOM 1352 SG CYS B 443 -16.614 16.476 6.001 0.86 46.20 S ANISOU 1352 SG CYS B 443 4240 6834 6480 13 427 2047 S ATOM 1353 N SER B 444 -17.867 19.417 7.715 1.00 79.80 N ANISOU 1353 N SER B 444 8286 11373 10662 554 803 2091 N ATOM 1354 CA SER B 444 -19.232 19.490 8.247 1.00 72.65 C ANISOU 1354 CA SER B 444 7178 10694 9732 634 885 2330 C ATOM 1355 C SER B 444 -20.052 18.191 8.145 1.00 66.75 C ANISOU 1355 C SER B 444 6301 10074 8986 436 782 2579 C ATOM 1356 O SER B 444 -21.251 18.202 8.417 1.00 69.30 O ANISOU 1356 O SER B 444 6429 10607 9294 470 832 2816 O ATOM 1357 CB SER B 444 -19.992 20.629 7.555 1.00 74.95 C ANISOU 1357 CB SER B 444 7374 11023 10081 741 942 2401 C ATOM 1358 OG SER B 444 -19.458 21.878 7.940 1.00 74.39 O ANISOU 1358 OG SER B 444 7411 10873 9982 958 1049 2209 O ATOM 1359 N ASP B 445 -19.427 17.089 7.731 1.00 61.05 N ANISOU 1359 N ASP B 445 5689 9229 8278 230 633 2537 N ATOM 1360 CA ASP B 445 -20.073 15.773 7.759 1.00 64.76 C ANISOU 1360 CA ASP B 445 6084 9793 8729 29 509 2759 C ATOM 1361 C ASP B 445 -20.287 15.354 9.227 1.00 74.96 C ANISOU 1361 C ASP B 445 7307 11246 9929 98 572 2829 C ATOM 1362 O ASP B 445 -19.907 16.075 10.161 1.00 61.06 O ANISOU 1362 O ASP B 445 5571 9508 8119 296 713 2696 O ATOM 1363 CB ASP B 445 -19.196 14.732 7.038 1.00 67.40 C ANISOU 1363 CB ASP B 445 6599 9920 9090 -175 339 2653 C ATOM 1364 CG ASP B 445 -19.981 13.498 6.575 1.00 82.20 C ANISOU 1364 CG ASP B 445 8430 11844 10958 -422 169 2899 C ATOM 1365 OD1 ASP B 445 -21.231 13.517 6.662 1.00 92.35 O ANISOU 1365 OD1 ASP B 445 9527 13335 12229 -455 176 3170 O ATOM 1366 OD2 ASP B 445 -19.346 12.512 6.110 1.00 73.68 O ANISOU 1366 OD2 ASP B 445 7512 10598 9884 -583 24 2827 O ATOM 1367 N GLU B 446 -20.898 14.197 9.441 1.00 84.34 N ANISOU 1367 N GLU B 446 8419 12543 11081 -78 457 3044 N ATOM 1368 CA GLU B 446 -21.077 13.697 10.799 1.00 79.25 C ANISOU 1368 CA GLU B 446 7713 12055 10344 -51 492 3120 C ATOM 1369 C GLU B 446 -19.723 13.393 11.411 1.00 64.98 C ANISOU 1369 C GLU B 446 6103 10068 8519 -30 473 2866 C ATOM 1370 O GLU B 446 -19.022 12.490 10.943 1.00 62.55 O ANISOU 1370 O GLU B 446 5937 9583 8247 -189 316 2793 O ATOM 1371 CB GLU B 446 -21.939 12.437 10.798 1.00 89.12 C ANISOU 1371 CB GLU B 446 8862 13442 11558 -286 331 3410 C ATOM 1372 CG GLU B 446 -23.359 12.672 11.286 1.00110.11 C ANISOU 1372 CG GLU B 446 11252 16426 14160 -239 418 3710 C ATOM 1373 CD GLU B 446 -23.392 13.269 12.681 1.00117.53 C ANISOU 1373 CD GLU B 446 12116 17530 15009 -16 616 3657 C ATOM 1374 OE1 GLU B 446 -23.829 14.435 12.815 1.00120.63 O ANISOU 1374 OE1 GLU B 446 12405 18027 15402 214 806 3645 O ATOM 1375 OE2 GLU B 446 -22.967 12.577 13.637 1.00115.39 O ANISOU 1375 OE2 GLU B 446 11904 17273 14665 -70 577 3622 O ATOM 1376 N ALA B 447 -19.358 14.140 12.455 1.00 46.56 N ANISOU 1376 N ALA B 447 3786 7776 6128 166 629 2739 N ATOM 1377 CA ALA B 447 -18.082 13.924 13.137 1.00 59.04 C ANISOU 1377 CA ALA B 447 5542 9201 7689 184 614 2519 C ATOM 1378 C ALA B 447 -18.102 12.604 13.908 1.00 74.17 C ANISOU 1378 C ALA B 447 7453 11173 9556 21 489 2631 C ATOM 1379 O ALA B 447 -19.150 12.165 14.373 1.00 69.00 O ANISOU 1379 O ALA B 447 6639 10738 8838 -42 480 2868 O ATOM 1380 CB ALA B 447 -17.781 15.065 14.068 1.00 61.54 C ANISOU 1380 CB ALA B 447 5892 9552 7940 414 801 2381 C ATOM 1381 N SER B 448 -16.933 11.983 14.038 1.00 77.57 N ANISOU 1381 N SER B 448 8051 11409 10015 -50 387 2470 N ATOM 1382 CA SER B 448 -16.820 10.662 14.637 1.00 68.40 C ANISOU 1382 CA SER B 448 6914 10250 8826 -221 231 2559 C ATOM 1383 C SER B 448 -15.983 10.704 15.909 1.00 73.94 C ANISOU 1383 C SER B 448 7694 10924 9476 -157 278 2432 C ATOM 1384 O SER B 448 -16.018 9.766 16.706 0.78 65.69 O ANISOU 1384 O SER B 448 6642 9931 8387 -279 176 2527 O ATOM 1385 CB SER B 448 -16.221 9.661 13.637 0.68 63.10 C ANISOU 1385 CB SER B 448 6377 9358 8241 -385 33 2508 C ATOM 1386 OG SER B 448 -14.799 9.731 13.589 1.00 56.71 O ANISOU 1386 OG SER B 448 5735 8325 7489 -327 25 2255 O ATOM 1387 N GLY B 449 -15.228 11.785 16.096 1.00 62.54 N ANISOU 1387 N GLY B 449 6333 9396 8034 17 416 2229 N ATOM 1388 CA GLY B 449 -14.473 11.970 17.325 1.00 58.81 C ANISOU 1388 CA GLY B 449 5943 8903 7498 77 469 2121 C ATOM 1389 C GLY B 449 -13.461 13.091 17.228 1.00 63.16 C ANISOU 1389 C GLY B 449 6627 9304 8067 231 572 1889 C ATOM 1390 O GLY B 449 -13.500 13.911 16.310 0.90 48.07 O ANISOU 1390 O GLY B 449 4722 7342 6199 320 632 1819 O ATOM 1391 N CYS B 450 -12.554 13.127 18.192 1.00 52.33 N ANISOU 1391 N CYS B 450 5364 7863 6655 245 578 1783 N ATOM 1392 CA CYS B 450 -11.491 14.115 18.208 1.00 54.95 C ANISOU 1392 CA CYS B 450 5839 8049 6990 361 646 1581 C ATOM 1393 C CYS B 450 -10.304 13.425 17.548 1.00 47.77 C ANISOU 1393 C CYS B 450 5020 6932 6197 263 498 1473 C ATOM 1394 O CYS B 450 -9.790 12.456 18.092 1.00 52.34 O ANISOU 1394 O CYS B 450 5630 7459 6796 154 385 1492 O ATOM 1395 CB CYS B 450 -11.182 14.511 19.667 1.00 58.61 C ANISOU 1395 CB CYS B 450 6377 8557 7333 412 726 1549 C ATOM 1396 SG CYS B 450 -10.552 16.195 19.923 1.00 85.09 S ANISOU 1396 SG CYS B 450 9890 11829 10611 604 876 1369 S ATOM 1397 N HIS B 451 -9.914 13.871 16.349 1.00 43.49 N ANISOU 1397 N HIS B 451 4512 6280 5733 301 495 1371 N ATOM 1398 CA HIS B 451 -8.819 13.224 15.605 1.00 37.33 C ANISOU 1398 CA HIS B 451 3807 5319 5059 227 373 1266 C ATOM 1399 C HIS B 451 -7.741 14.217 15.251 1.00 43.01 C ANISOU 1399 C HIS B 451 4625 5924 5794 316 423 1092 C ATOM 1400 O HIS B 451 -8.027 15.305 14.718 1.00 39.39 O ANISOU 1400 O HIS B 451 4166 5488 5312 407 513 1050 O ATOM 1401 CB HIS B 451 -9.335 12.581 14.315 1.00 36.56 C ANISOU 1401 CB HIS B 451 3660 5195 5038 146 293 1320 C ATOM 1402 CG HIS B 451 -10.482 11.649 14.512 1.00 46.44 C ANISOU 1402 CG HIS B 451 4814 6565 6266 37 224 1518 C ATOM 1403 ND1 HIS B 451 -10.335 10.409 15.104 1.00 47.81 N ANISOU 1403 ND1 HIS B 451 5004 6715 6448 -83 90 1589 N ATOM 1404 CD2 HIS B 451 -11.793 11.764 14.193 1.00 53.22 C ANISOU 1404 CD2 HIS B 451 5555 7573 7092 20 256 1677 C ATOM 1405 CE1 HIS B 451 -11.512 9.805 15.141 1.00 49.06 C ANISOU 1405 CE1 HIS B 451 5066 7006 6570 -181 37 1785 C ATOM 1406 NE2 HIS B 451 -12.411 10.604 14.596 1.00 55.81 N ANISOU 1406 NE2 HIS B 451 5830 7974 7400 -120 140 1847 N ATOM 1407 N TYR B 452 -6.498 13.849 15.536 1.00 38.14 N ANISOU 1407 N TYR B 452 4087 5186 5216 284 353 1004 N ATOM 1408 CA TYR B 452 -5.387 14.760 15.297 1.00 49.22 C ANISOU 1408 CA TYR B 452 5580 6498 6623 349 385 862 C ATOM 1409 C TYR B 452 -5.718 16.124 15.906 1.00 45.48 C ANISOU 1409 C TYR B 452 5154 6092 6036 456 508 846 C ATOM 1410 O TYR B 452 -5.308 17.150 15.392 1.00 39.54 O ANISOU 1410 O TYR B 452 4460 5295 5268 520 548 755 O ATOM 1411 CB TYR B 452 -5.059 14.827 13.773 1.00 40.75 C ANISOU 1411 CB TYR B 452 4501 5350 5634 345 359 780 C ATOM 1412 CG TYR B 452 -4.800 13.430 13.231 1.00 39.66 C ANISOU 1412 CG TYR B 452 4342 5134 5591 255 242 792 C ATOM 1413 CD1 TYR B 452 -5.580 12.900 12.212 0.73 42.25 C ANISOU 1413 CD1 TYR B 452 4627 5468 5958 201 207 840 C ATOM 1414 CD2 TYR B 452 -3.828 12.611 13.811 0.99 48.61 C ANISOU 1414 CD2 TYR B 452 5513 6185 6772 219 158 768 C ATOM 1415 CE1 TYR B 452 -5.370 11.612 11.741 1.00 46.00 C ANISOU 1415 CE1 TYR B 452 5121 5854 6505 121 93 848 C ATOM 1416 CE2 TYR B 452 -3.607 11.315 13.348 1.00 44.32 C ANISOU 1416 CE2 TYR B 452 4971 5554 6314 154 46 775 C ATOM 1417 CZ TYR B 452 -4.396 10.830 12.302 1.00 47.76 C ANISOU 1417 CZ TYR B 452 5386 5985 6773 108 15 810 C ATOM 1418 OH TYR B 452 -4.219 9.559 11.820 0.97 46.36 O ANISOU 1418 OH TYR B 452 5246 5705 6665 45 -103 813 O ATOM 1419 N GLY B 453 -6.476 16.115 17.007 1.00 44.08 N ANISOU 1419 N GLY B 453 4957 6023 5767 474 564 937 N ATOM 1420 CA GLY B 453 -6.630 17.281 17.871 1.00 40.71 C ANISOU 1420 CA GLY B 453 4615 5641 5212 580 678 912 C ATOM 1421 C GLY B 453 -7.860 18.105 17.565 1.00 46.14 C ANISOU 1421 C GLY B 453 5245 6439 5846 699 799 955 C ATOM 1422 O GLY B 453 -8.052 19.196 18.099 1.00 57.42 O ANISOU 1422 O GLY B 453 6757 7890 7168 820 903 919 O ATOM 1423 N VAL B 454 -8.720 17.572 16.712 1.00 40.35 N ANISOU 1423 N VAL B 454 4375 5773 5185 666 780 1041 N ATOM 1424 CA VAL B 454 -9.828 18.345 16.206 1.00 44.32 C ANISOU 1424 CA VAL B 454 4801 6371 5666 772 879 1093 C ATOM 1425 C VAL B 454 -11.035 17.464 16.042 1.00 45.99 C ANISOU 1425 C VAL B 454 4842 6729 5904 709 865 1270 C ATOM 1426 O VAL B 454 -10.905 16.298 15.706 1.00 58.99 O ANISOU 1426 O VAL B 454 6444 8347 7622 566 745 1322 O ATOM 1427 CB VAL B 454 -9.453 18.954 14.797 0.77 39.30 C ANISOU 1427 CB VAL B 454 4191 5629 5113 781 846 999 C ATOM 1428 CG1 VAL B 454 -10.617 19.730 14.221 1.00 39.03 C ANISOU 1428 CG1 VAL B 454 4070 5685 5074 880 931 1066 C ATOM 1429 CG2 VAL B 454 -8.218 19.834 14.917 0.92 37.19 C ANISOU 1429 CG2 VAL B 454 4090 5229 4812 822 839 842 C ATOM 1430 N LEU B 455 -12.211 18.035 16.227 1.00 51.11 N ANISOU 1430 N LEU B 455 5395 7530 6495 818 982 1370 N ATOM 1431 CA LEU B 455 -13.459 17.338 15.945 1.00 61.19 C ANISOU 1431 CA LEU B 455 6487 8969 7794 757 970 1569 C ATOM 1432 C LEU B 455 -13.635 17.083 14.425 1.00 59.64 C ANISOU 1432 C LEU B 455 6237 8707 7716 667 877 1595 C ATOM 1433 O LEU B 455 -13.864 18.024 13.633 1.00 45.29 O ANISOU 1433 O LEU B 455 4414 6865 5929 753 928 1558 O ATOM 1434 CB LEU B 455 -14.624 18.165 16.505 1.00 70.21 C ANISOU 1434 CB LEU B 455 7532 10300 8843 927 1137 1668 C ATOM 1435 CG LEU B 455 -15.820 17.419 17.084 1.00 94.67 C ANISOU 1435 CG LEU B 455 10445 13637 11890 882 1162 1895 C ATOM 1436 CD1 LEU B 455 -16.904 18.404 17.466 1.00109.68 C ANISOU 1436 CD1 LEU B 455 12244 15719 13710 1090 1349 1974 C ATOM 1437 CD2 LEU B 455 -16.348 16.428 16.096 1.00 99.66 C ANISOU 1437 CD2 LEU B 455 10951 14297 12618 705 1023 2048 C ATOM 1438 N THR B 456 -13.536 15.827 13.996 1.00 50.84 N ANISOU 1438 N THR B 456 5098 7556 6665 489 733 1660 N ATOM 1439 CA THR B 456 -13.720 15.533 12.566 1.00 53.61 C ANISOU 1439 CA THR B 456 5422 7838 7109 389 643 1687 C ATOM 1440 C THR B 456 -14.436 14.226 12.271 1.00 58.05 C ANISOU 1440 C THR B 456 5899 8461 7695 210 515 1873 C ATOM 1441 O THR B 456 -14.551 13.343 13.125 1.00 46.23 O ANISOU 1441 O THR B 456 4381 7027 6157 135 459 1962 O ATOM 1442 CB THR B 456 -12.367 15.446 11.824 1.00 52.65 C ANISOU 1442 CB THR B 456 5447 7501 7057 344 564 1490 C ATOM 1443 OG1 THR B 456 -11.647 14.280 12.257 1.00 48.70 O ANISOU 1443 OG1 THR B 456 5009 6923 6573 239 455 1466 O ATOM 1444 CG2 THR B 456 -11.530 16.693 12.075 1.00 41.37 C ANISOU 1444 CG2 THR B 456 4120 6001 5598 487 657 1314 C ATOM 1445 N CYS B 457 -14.886 14.101 11.033 1.00 47.93 N ANISOU 1445 N CYS B 457 4585 7151 6476 124 451 1936 N ATOM 1446 CA CYS B 457 -15.410 12.848 10.514 1.00 49.88 C ANISOU 1446 CA CYS B 457 4804 7403 6746 -74 296 2095 C ATOM 1447 C CYS B 457 -14.232 11.942 10.245 1.00 48.69 C ANISOU 1447 C CYS B 457 4816 7045 6638 -166 170 1947 C ATOM 1448 O CYS B 457 -13.085 12.376 10.338 1.00 44.79 O ANISOU 1448 O CYS B 457 4426 6428 6166 -76 213 1740 O ATOM 1449 CB CYS B 457 -16.185 13.102 9.214 1.00 57.48 C ANISOU 1449 CB CYS B 457 5707 8377 7755 -142 268 2197 C ATOM 1450 SG CYS B 457 -15.133 13.609 7.798 1.00 53.02 S ANISOU 1450 SG CYS B 457 5294 7582 7269 -147 247 1963 S ATOM 1451 N GLY B 458 -14.497 10.694 9.881 1.00 57.49 N ANISOU 1451 N GLY B 458 5960 8119 7765 -342 8 2058 N ATOM 1452 CA GLY B 458 -13.428 9.748 9.603 1.00 53.11 C ANISOU 1452 CA GLY B 458 5568 7360 7253 -415 -116 1923 C ATOM 1453 C GLY B 458 -12.708 10.036 8.289 1.00 54.88 C ANISOU 1453 C GLY B 458 5900 7414 7538 -408 -118 1753 C ATOM 1454 O GLY B 458 -11.496 9.857 8.173 1.00 49.35 O ANISOU 1454 O GLY B 458 5314 6560 6875 -366 -131 1563 O ATOM 1455 N SER B 459 -13.460 10.468 7.286 1.00 48.39 N ANISOU 1455 N SER B 459 5032 6629 6725 -458 -108 1831 N ATOM 1456 CA SER B 459 -12.880 10.704 5.976 1.00 47.88 C ANISOU 1456 CA SER B 459 5069 6418 6704 -481 -118 1688 C ATOM 1457 C SER B 459 -11.799 11.787 6.086 1.00 38.29 C ANISOU 1457 C SER B 459 3881 5158 5509 -316 9 1466 C ATOM 1458 O SER B 459 -10.687 11.628 5.573 1.00 42.47 O ANISOU 1458 O SER B 459 4523 5545 6069 -304 -9 1287 O ATOM 1459 CB SER B 459 -13.965 11.039 4.942 1.00 44.62 C ANISOU 1459 CB SER B 459 4592 6066 6293 -581 -136 1837 C ATOM 1460 OG SER B 459 -14.651 12.255 5.205 1.00 48.93 O ANISOU 1460 OG SER B 459 4989 6768 6835 -473 -8 1908 O ATOM 1461 N CYS B 460 -12.090 12.839 6.830 1.00 35.96 N ANISOU 1461 N CYS B 460 3489 4987 5188 -188 131 1484 N ATOM 1462 CA CYS B 460 -11.120 13.902 7.035 1.00 41.01 C ANISOU 1462 CA CYS B 460 4170 5585 5829 -46 232 1297 C ATOM 1463 C CYS B 460 -9.937 13.436 7.852 1.00 51.70 C ANISOU 1463 C CYS B 460 5605 6857 7182 -3 215 1172 C ATOM 1464 O CYS B 460 -8.805 13.820 7.557 1.00 39.35 O ANISOU 1464 O CYS B 460 4117 5197 5638 46 235 1002 O ATOM 1465 CB CYS B 460 -11.795 15.127 7.649 1.00 43.70 C ANISOU 1465 CB CYS B 460 4415 6062 6128 86 358 1353 C ATOM 1466 SG CYS B 460 -12.876 15.946 6.398 1.00 42.73 S ANISOU 1466 SG CYS B 460 4206 5996 6035 55 378 1455 S ATOM 1467 N LYS B 461 -10.184 12.582 8.850 1.00 43.85 N ANISOU 1467 N LYS B 461 4590 5906 6166 -34 168 1269 N ATOM 1468 CA LYS B 461 -9.104 12.003 9.638 1.00 39.35 C ANISOU 1468 CA LYS B 461 4093 5251 5607 -15 129 1174 C ATOM 1469 C LYS B 461 -8.111 11.265 8.763 1.00 38.60 C ANISOU 1469 C LYS B 461 4104 4987 5576 -63 43 1048 C ATOM 1470 O LYS B 461 -6.912 11.552 8.802 1.00 35.24 O ANISOU 1470 O LYS B 461 3732 4481 5175 8 70 895 O ATOM 1471 CB LYS B 461 -9.664 11.067 10.735 1.00 44.31 C ANISOU 1471 CB LYS B 461 4681 5954 6202 -79 62 1324 C ATOM 1472 CG LYS B 461 -8.669 10.045 11.287 1.00 44.70 C ANISOU 1472 CG LYS B 461 4814 5882 6286 -114 -41 1261 C ATOM 1473 CD LYS B 461 -9.334 9.207 12.415 1.00 57.08 C ANISOU 1473 CD LYS B 461 6335 7544 7810 -197 -116 1428 C ATOM 1474 CE LYS B 461 -9.105 7.710 12.282 1.00 64.41 C ANISOU 1474 CE LYS B 461 7341 8350 8783 -322 -301 1465 C ATOM 1475 NZ LYS B 461 -7.712 7.341 11.929 1.00 55.43 N ANISOU 1475 NZ LYS B 461 6317 7018 7726 -277 -345 1285 N ATOM 1476 N VAL B 462 -8.580 10.308 7.955 1.00 42.63 N ANISOU 1476 N VAL B 462 4650 5441 6108 -181 -63 1115 N ATOM 1477 CA VAL B 462 -7.630 9.563 7.110 1.00 28.98 C ANISOU 1477 CA VAL B 462 3040 3541 4429 -207 -135 982 C ATOM 1478 C VAL B 462 -7.083 10.440 6.002 1.00 33.51 C ANISOU 1478 C VAL B 462 3636 4079 5016 -163 -57 840 C ATOM 1479 O VAL B 462 -5.920 10.280 5.608 1.00 37.27 O ANISOU 1479 O VAL B 462 4181 4453 5525 -116 -54 685 O ATOM 1480 CB VAL B 462 -8.219 8.256 6.489 1.00 71.67 C ANISOU 1480 CB VAL B 462 8526 8867 9839 -351 -283 1078 C ATOM 1481 CG1 VAL B 462 -8.699 7.305 7.596 1.00 88.57 C ANISOU 1481 CG1 VAL B 462 10651 11041 11961 -416 -389 1226 C ATOM 1482 CG2 VAL B 462 -9.330 8.567 5.507 1.00 58.22 C ANISOU 1482 CG2 VAL B 462 6794 7220 8106 -451 -287 1189 C ATOM 1483 N PHE B 463 -7.884 11.392 5.529 1.00 31.78 N ANISOU 1483 N PHE B 463 3351 3953 4771 -174 6 898 N ATOM 1484 CA PHE B 463 -7.394 12.292 4.450 1.00 31.02 C ANISOU 1484 CA PHE B 463 3276 3829 4682 -152 67 772 C ATOM 1485 C PHE B 463 -6.192 13.077 4.962 1.00 31.80 C ANISOU 1485 C PHE B 463 3377 3923 4781 -29 142 626 C ATOM 1486 O PHE B 463 -5.154 13.173 4.299 1.00 32.96 O ANISOU 1486 O PHE B 463 3576 4003 4945 -11 152 484 O ATOM 1487 CB PHE B 463 -8.475 13.290 3.982 1.00 30.97 C ANISOU 1487 CB PHE B 463 3189 3924 4655 -177 115 870 C ATOM 1488 CG PHE B 463 -7.909 14.398 3.106 1.00 38.30 C ANISOU 1488 CG PHE B 463 4132 4837 5584 -148 174 742 C ATOM 1489 CD1 PHE B 463 -7.733 14.196 1.741 1.00 34.01 C ANISOU 1489 CD1 PHE B 463 3651 4220 5050 -248 135 683 C ATOM 1490 CD2 PHE B 463 -7.503 15.607 3.664 1.00 36.37 C ANISOU 1490 CD2 PHE B 463 3856 4644 5319 -32 256 679 C ATOM 1491 CE1 PHE B 463 -7.188 15.206 0.923 1.00 33.19 C ANISOU 1491 CE1 PHE B 463 3557 4114 4939 -240 178 570 C ATOM 1492 CE2 PHE B 463 -6.970 16.631 2.865 1.00 32.77 C ANISOU 1492 CE2 PHE B 463 3421 4175 4856 -23 287 572 C ATOM 1493 CZ PHE B 463 -6.805 16.422 1.484 0.89 30.27 C ANISOU 1493 CZ PHE B 463 3146 3803 4553 -132 247 519 C ATOM 1494 N PHE B 464 -6.327 13.637 6.170 1.00 32.64 N ANISOU 1494 N PHE B 464 3432 4109 4859 50 194 671 N ATOM 1495 CA PHE B 464 -5.235 14.440 6.747 1.00 35.36 C ANISOU 1495 CA PHE B 464 3797 4450 5189 149 251 557 C ATOM 1496 C PHE B 464 -4.005 13.581 6.956 1.00 33.84 C ANISOU 1496 C PHE B 464 3656 4164 5039 159 201 468 C ATOM 1497 O PHE B 464 -2.902 13.977 6.620 1.00 31.23 O ANISOU 1497 O PHE B 464 3350 3799 4718 197 221 350 O ATOM 1498 CB PHE B 464 -5.647 15.095 8.090 1.00 38.62 C ANISOU 1498 CB PHE B 464 4176 4952 5547 224 309 627 C ATOM 1499 CG PHE B 464 -4.529 15.880 8.751 1.00 33.03 C ANISOU 1499 CG PHE B 464 3517 4224 4809 303 347 527 C ATOM 1500 CD1 PHE B 464 -4.183 17.148 8.290 1.00 35.48 C ANISOU 1500 CD1 PHE B 464 3854 4541 5086 345 392 451 C ATOM 1501 CD2 PHE B 464 -3.830 15.355 9.832 1.00 39.17 C ANISOU 1501 CD2 PHE B 464 4320 4974 5587 317 319 523 C ATOM 1502 CE1 PHE B 464 -3.153 17.872 8.887 0.82 38.02 C ANISOU 1502 CE1 PHE B 464 4235 4843 5366 395 405 379 C ATOM 1503 CE2 PHE B 464 -2.798 16.077 10.433 0.86 37.81 C ANISOU 1503 CE2 PHE B 464 4200 4784 5382 367 339 453 C ATOM 1504 CZ PHE B 464 -2.459 17.328 9.951 1.00 36.18 C ANISOU 1504 CZ PHE B 464 4028 4585 5133 403 380 384 C ATOM 1505 N LYS B 465 -4.186 12.387 7.524 1.00 30.72 N ANISOU 1505 N LYS B 465 3271 3731 4669 124 128 534 N ATOM 1506 CA LYS B 465 -3.029 11.525 7.793 1.00 30.91 C ANISOU 1506 CA LYS B 465 3340 3657 4746 147 73 459 C ATOM 1507 C LYS B 465 -2.282 11.197 6.479 1.00 34.38 C ANISOU 1507 C LYS B 465 3830 4009 5225 147 64 335 C ATOM 1508 O LYS B 465 -1.051 11.235 6.378 1.00 35.18 O ANISOU 1508 O LYS B 465 3940 4071 5356 210 80 228 O ATOM 1509 CB LYS B 465 -3.529 10.243 8.503 1.00 37.29 C ANISOU 1509 CB LYS B 465 4163 4431 5575 89 -28 566 C ATOM 1510 CG LYS B 465 -2.516 9.124 8.552 1.00 37.57 C ANISOU 1510 CG LYS B 465 4258 4335 5680 106 -111 499 C ATOM 1511 CD LYS B 465 -1.336 9.514 9.460 1.00 38.79 C ANISOU 1511 CD LYS B 465 4389 4491 5857 185 -82 443 C ATOM 1512 CE LYS B 465 -0.553 8.261 9.900 1.00 45.73 C ANISOU 1512 CE LYS B 465 5306 5252 6815 196 -187 432 C ATOM 1513 NZ LYS B 465 0.588 8.651 10.735 1.00 50.41 N ANISOU 1513 NZ LYS B 465 5868 5852 7435 256 -166 399 N ATOM 1514 N ARG B 466 -3.040 10.851 5.450 1.00 32.41 N ANISOU 1514 N ARG B 466 3612 3733 4967 71 37 358 N ATOM 1515 CA ARG B 466 -2.438 10.573 4.152 0.95 33.68 C ANISOU 1515 CA ARG B 466 3836 3817 5144 64 38 238 C ATOM 1516 C ARG B 466 -1.736 11.806 3.584 1.00 37.89 C ANISOU 1516 C ARG B 466 4331 4411 5653 106 129 135 C ATOM 1517 O ARG B 466 -0.652 11.716 3.016 0.81 31.95 O ANISOU 1517 O ARG B 466 3597 3625 4916 150 153 15 O ATOM 1518 CB ARG B 466 -3.521 10.116 3.199 1.00 39.43 C ANISOU 1518 CB ARG B 466 4619 4513 5848 -53 -12 304 C ATOM 1519 CG ARG B 466 -3.692 8.613 3.209 0.79 43.44 C ANISOU 1519 CG ARG B 466 5228 4900 6378 -100 -128 340 C ATOM 1520 CD ARG B 466 -5.057 8.240 2.760 1.00 51.72 C ANISOU 1520 CD ARG B 466 6310 5951 7389 -243 -203 485 C ATOM 1521 NE ARG B 466 -5.302 6.828 2.999 1.00 69.92 N ANISOU 1521 NE ARG B 466 8718 8144 9702 -302 -340 550 N ATOM 1522 CZ ARG B 466 -6.504 6.279 3.077 1.00 69.08 C ANISOU 1522 CZ ARG B 466 8633 8053 9562 -437 -444 728 C ATOM 1523 NH1 ARG B 466 -7.591 7.024 2.933 1.00 58.25 N ANISOU 1523 NH1 ARG B 466 7165 6813 8155 -514 -412 862 N ATOM 1524 NH2 ARG B 466 -6.614 4.983 3.307 1.00 75.36 N ANISOU 1524 NH2 ARG B 466 9541 8734 10359 -497 -588 781 N ATOM 1525 N ALA B 467 -2.340 12.968 3.768 1.00 33.88 N ANISOU 1525 N ALA B 467 3769 4000 5104 95 176 189 N ATOM 1526 CA ALA B 467 -1.773 14.186 3.193 1.00 40.30 C ANISOU 1526 CA ALA B 467 4560 4867 5886 113 236 106 C ATOM 1527 C ALA B 467 -0.453 14.550 3.874 1.00 38.33 C ANISOU 1527 C ALA B 467 4293 4632 5639 197 259 37 C ATOM 1528 O ALA B 467 0.502 14.976 3.201 1.00 40.39 O ANISOU 1528 O ALA B 467 4549 4910 5889 208 284 -58 O ATOM 1529 CB ALA B 467 -2.762 15.312 3.296 1.00 27.10 C ANISOU 1529 CB ALA B 467 2849 3274 4173 95 267 185 C ATOM 1530 N VAL B 468 -0.374 14.352 5.193 1.00 38.08 N ANISOU 1530 N VAL B 468 4250 4601 5617 244 245 95 N ATOM 1531 CA VAL B 468 0.835 14.756 5.930 1.00 40.74 C ANISOU 1531 CA VAL B 468 4576 4953 5952 303 253 57 C ATOM 1532 C VAL B 468 1.977 13.764 5.802 1.00 48.95 C ANISOU 1532 C VAL B 468 5611 5932 7057 342 226 -6 C ATOM 1533 O VAL B 468 3.142 14.154 5.953 1.00 44.64 O ANISOU 1533 O VAL B 468 5038 5414 6512 380 237 -47 O ATOM 1534 CB VAL B 468 0.579 15.056 7.436 1.00 47.94 C ANISOU 1534 CB VAL B 468 5491 5890 6835 329 250 142 C ATOM 1535 CG1 VAL B 468 -0.443 16.161 7.563 1.00 50.35 C ANISOU 1535 CG1 VAL B 468 5802 6260 7069 325 294 192 C ATOM 1536 CG2 VAL B 468 0.148 13.808 8.197 1.00 40.60 C ANISOU 1536 CG2 VAL B 468 4563 4913 5951 318 197 215 C ATOM 1537 N GLU B 469 1.647 12.504 5.487 1.00 44.84 N ANISOU 1537 N GLU B 469 5122 5329 6588 333 185 -7 N ATOM 1538 CA GLU B 469 2.645 11.430 5.389 1.00 52.67 C ANISOU 1538 CA GLU B 469 6123 6241 7650 393 155 -67 C ATOM 1539 C GLU B 469 3.249 11.344 4.001 1.00 60.71 C ANISOU 1539 C GLU B 469 7151 7250 8664 414 198 -185 C ATOM 1540 O GLU B 469 4.324 10.776 3.810 1.00 70.04 O ANISOU 1540 O GLU B 469 8319 8399 9893 495 206 -253 O ATOM 1541 CB GLU B 469 2.023 10.070 5.736 1.00 49.20 C ANISOU 1541 CB GLU B 469 5741 5695 7257 375 70 -13 C ATOM 1542 CG GLU B 469 1.645 9.921 7.191 1.00 64.98 C ANISOU 1542 CG GLU B 469 7722 7704 9264 357 19 101 C ATOM 1543 CD GLU B 469 2.856 10.036 8.103 1.00 79.24 C ANISOU 1543 CD GLU B 469 9483 9515 11109 419 14 95 C ATOM 1544 OE1 GLU B 469 3.989 9.979 7.574 1.00 84.78 O ANISOU 1544 OE1 GLU B 469 10160 10202 11849 488 39 10 O ATOM 1545 OE2 GLU B 469 2.685 10.183 9.337 1.00 74.04 O ANISOU 1545 OE2 GLU B 469 8811 8882 10439 395 -15 182 O ATOM 1546 N GLY B 470 2.529 11.853 3.015 1.00 54.57 N ANISOU 1546 N GLY B 470 6399 6503 7833 343 227 -203 N ATOM 1547 CA GLY B 470 3.083 11.943 1.684 1.00 58.90 C ANISOU 1547 CA GLY B 470 6958 7065 8356 343 276 -314 C ATOM 1548 C GLY B 470 3.441 13.380 1.392 0.63 65.40 C ANISOU 1548 C GLY B 470 7717 8013 9119 313 326 -331 C ATOM 1549 O GLY B 470 3.765 14.188 2.293 1.00 54.71 O ANISOU 1549 O GLY B 470 6314 6721 7753 330 323 -282 O ATOM 1550 N GLN B 471 3.343 13.693 0.110 1.00 80.78 N ANISOU 1550 N GLN B 471 9685 9988 11020 252 358 -396 N ATOM 1551 CA GLN B 471 3.451 15.055 -0.375 1.00 86.38 C ANISOU 1551 CA GLN B 471 10352 10807 11663 189 382 -405 C ATOM 1552 C GLN B 471 2.028 15.567 -0.443 1.00 83.51 C ANISOU 1552 C GLN B 471 10020 10432 11277 99 355 -326 C ATOM 1553 O GLN B 471 1.072 14.798 -0.612 1.00 78.68 O ANISOU 1553 O GLN B 471 9461 9745 10687 60 328 -285 O ATOM 1554 CB GLN B 471 4.110 15.125 -1.757 1.00 89.65 C ANISOU 1554 CB GLN B 471 10762 11268 12032 156 427 -512 C ATOM 1555 CG GLN B 471 4.031 13.840 -2.561 1.00103.13 C ANISOU 1555 CG GLN B 471 12550 12879 13756 172 443 -586 C ATOM 1556 CD GLN B 471 4.603 12.654 -1.809 1.00117.31 C ANISOU 1556 CD GLN B 471 14356 14590 15627 304 436 -599 C ATOM 1557 OE1 GLN B 471 4.005 11.576 -1.785 1.00119.50 O ANISOU 1557 OE1 GLN B 471 14728 14740 15937 310 396 -591 O ATOM 1558 NE2 GLN B 471 5.739 12.861 -1.146 1.00121.47 N ANISOU 1558 NE2 GLN B 471 14789 15184 16182 398 456 -601 N ATOM 1559 N HIS B 472 1.878 16.863 -0.259 1.00 71.28 N ANISOU 1559 N HIS B 472 8441 8957 9684 68 352 -290 N ATOM 1560 CA HIS B 472 0.576 17.470 -0.397 1.00 68.47 C ANISOU 1560 CA HIS B 472 8099 8603 9312 -1 334 -214 C ATOM 1561 C HIS B 472 0.740 18.611 -1.398 1.00 69.98 C ANISOU 1561 C HIS B 472 8282 8861 9446 -84 332 -253 C ATOM 1562 O HIS B 472 0.298 19.727 -1.146 1.00 53.86 O ANISOU 1562 O HIS B 472 6235 6853 7376 -99 314 -204 O ATOM 1563 CB HIS B 472 0.055 17.961 0.961 1.00 45.38 C ANISOU 1563 CB HIS B 472 5164 5689 6390 61 328 -121 C ATOM 1564 CG HIS B 472 1.131 18.483 1.866 1.00 54.98 C ANISOU 1564 CG HIS B 472 6369 6938 7583 129 330 -140 C ATOM 1565 ND1 HIS B 472 1.450 17.885 3.068 1.00 67.08 N ANISOU 1565 ND1 HIS B 472 7900 8441 9145 202 326 -107 N ATOM 1566 CD2 HIS B 472 1.951 19.555 1.754 1.00 51.36 C ANISOU 1566 CD2 HIS B 472 5908 6539 7069 117 321 -174 C ATOM 1567 CE1 HIS B 472 2.427 18.561 3.649 1.00 65.88 C ANISOU 1567 CE1 HIS B 472 7746 8326 8958 230 317 -117 C ATOM 1568 NE2 HIS B 472 2.755 19.573 2.867 1.00 57.44 N ANISOU 1568 NE2 HIS B 472 6678 7313 7835 179 311 -155 N ATOM 1569 N ASN B 473 1.411 18.322 -2.516 1.00 73.81 N ANISOU 1569 N ASN B 473 8771 9364 9910 -135 348 -344 N ATOM 1570 CA ASN B 473 1.574 19.303 -3.579 1.00 68.33 C ANISOU 1570 CA ASN B 473 8069 8740 9154 -241 337 -380 C ATOM 1571 C ASN B 473 0.333 19.285 -4.462 1.00 62.45 C ANISOU 1571 C ASN B 473 7362 7953 8412 -359 312 -338 C ATOM 1572 O ASN B 473 0.372 18.919 -5.633 1.00 71.60 O ANISOU 1572 O ASN B 473 8554 9105 9545 -453 318 -393 O ATOM 1573 CB ASN B 473 2.835 19.020 -4.390 1.00 72.41 C ANISOU 1573 CB ASN B 473 8563 9317 9632 -249 374 -490 C ATOM 1574 CG ASN B 473 3.107 20.094 -5.434 1.00 79.35 C ANISOU 1574 CG ASN B 473 9424 10291 10433 -376 352 -520 C ATOM 1575 OD1 ASN B 473 2.813 21.277 -5.221 1.00 72.74 O ANISOU 1575 OD1 ASN B 473 8580 9487 9569 -424 297 -464 O ATOM 1576 ND2 ASN B 473 3.665 19.685 -6.573 1.00 88.05 N ANISOU 1576 ND2 ASN B 473 10527 11435 11492 -431 391 -609 N ATOM 1577 N TYR B 474 -0.781 19.658 -3.853 0.60 42.07 N ANISOU 1577 N TYR B 474 4777 5347 5861 -351 285 -230 N ATOM 1578 CA TYR B 474 -2.087 19.623 -4.491 1.00 42.19 C ANISOU 1578 CA TYR B 474 4808 5328 5893 -455 254 -147 C ATOM 1579 C TYR B 474 -2.247 20.960 -5.128 0.85 38.40 C ANISOU 1579 C TYR B 474 4311 4900 5379 -541 218 -137 C ATOM 1580 O TYR B 474 -1.573 21.915 -4.733 1.00 46.92 O ANISOU 1580 O TYR B 474 5374 6029 6424 -496 210 -169 O ATOM 1581 CB TYR B 474 -3.179 19.492 -3.420 1.00 48.38 C ANISOU 1581 CB TYR B 474 5567 6091 6725 -385 250 -18 C ATOM 1582 CG TYR B 474 -3.230 18.188 -2.669 1.00 51.20 C ANISOU 1582 CG TYR B 474 5941 6395 7118 -317 262 4 C ATOM 1583 CD1 TYR B 474 -3.293 18.167 -1.280 1.00 50.47 C ANISOU 1583 CD1 TYR B 474 5819 6314 7043 -198 279 55 C ATOM 1584 CD2 TYR B 474 -3.267 16.987 -3.342 0.89 54.55 C ANISOU 1584 CD2 TYR B 474 6426 6751 7550 -381 244 -19 C ATOM 1585 CE1 TYR B 474 -3.363 16.992 -0.594 1.00 44.20 C ANISOU 1585 CE1 TYR B 474 5039 5474 6281 -155 272 85 C ATOM 1586 CE2 TYR B 474 -3.332 15.801 -2.664 1.00 58.94 C ANISOU 1586 CE2 TYR B 474 7012 7247 8137 -328 232 7 C ATOM 1587 CZ TYR B 474 -3.382 15.803 -1.284 1.00 61.67 C ANISOU 1587 CZ TYR B 474 7310 7613 8507 -220 242 64 C ATOM 1588 OH TYR B 474 -3.461 14.598 -0.615 0.81 51.33 O ANISOU 1588 OH TYR B 474 6032 6244 7229 -185 212 99 O ATOM 1589 N LEU B 475 -3.165 21.081 -6.072 1.00 42.72 N ANISOU 1589 N LEU B 475 4869 5431 5934 -674 180 -80 N ATOM 1590 CA LEU B 475 -3.347 22.368 -6.751 1.00 40.92 C ANISOU 1590 CA LEU B 475 4625 5243 5679 -771 127 -64 C ATOM 1591 C LEU B 475 -4.794 22.736 -6.793 1.00 40.59 C ANISOU 1591 C LEU B 475 4556 5178 5689 -811 89 80 C ATOM 1592 O LEU B 475 -5.614 21.929 -7.204 1.00 38.31 O ANISOU 1592 O LEU B 475 4275 4850 5430 -888 79 155 O ATOM 1593 CB LEU B 475 -2.795 22.302 -8.175 1.00 43.86 C ANISOU 1593 CB LEU B 475 5031 5639 5996 -934 109 -150 C ATOM 1594 CG LEU B 475 -1.558 23.184 -8.365 1.00 58.11 C ANISOU 1594 CG LEU B 475 6820 7529 7731 -944 98 -244 C ATOM 1595 CD1 LEU B 475 -0.361 22.627 -7.626 1.00 56.48 C ANISOU 1595 CD1 LEU B 475 6601 7352 7508 -808 162 -328 C ATOM 1596 CD2 LEU B 475 -1.256 23.295 -9.850 1.00 71.57 C ANISOU 1596 CD2 LEU B 475 8546 9274 9372 -1133 72 -304 C ATOM 1597 N CYS B 476 -5.111 23.948 -6.341 1.00 28.24 N ANISOU 1597 N CYS B 476 2965 3636 4131 -754 62 128 N ATOM 1598 CA CYS B 476 -6.499 24.436 -6.363 1.00 36.59 C ANISOU 1598 CA CYS B 476 3976 4682 5244 -766 31 275 C ATOM 1599 C CYS B 476 -6.785 24.951 -7.786 1.00 39.50 C ANISOU 1599 C CYS B 476 4350 5048 5609 -967 -49 295 C ATOM 1600 O CYS B 476 -5.941 25.602 -8.361 1.00 35.37 O ANISOU 1600 O CYS B 476 3860 4547 5032 -1041 -89 201 O ATOM 1601 CB CYS B 476 -6.674 25.569 -5.303 1.00 27.24 C ANISOU 1601 CB CYS B 476 2780 3508 4061 -600 39 303 C ATOM 1602 SG CYS B 476 -8.363 26.260 -5.279 1.00 33.18 S ANISOU 1602 SG CYS B 476 3459 4261 4888 -569 18 487 S ATOM 1603 N ALA B 477 -7.959 24.661 -8.337 1.00 31.02 N ANISOU 1603 N ALA B 477 3242 3954 4589 -1070 -82 430 N ATOM 1604 CA ALA B 477 -8.386 25.152 -9.650 1.00 31.24 C ANISOU 1604 CA ALA B 477 3273 3974 4623 -1278 -170 478 C ATOM 1605 C ALA B 477 -9.218 26.427 -9.520 1.00 34.12 C ANISOU 1605 C ALA B 477 3577 4344 5044 -1239 -225 590 C ATOM 1606 O ALA B 477 -9.594 27.037 -10.531 1.00 35.67 O ANISOU 1606 O ALA B 477 3766 4530 5256 -1404 -315 642 O ATOM 1607 CB ALA B 477 -9.256 24.075 -10.363 1.00 30.12 C ANISOU 1607 CB ALA B 477 3137 3799 4507 -1435 -192 590 C ATOM 1608 N GLY B 478 -9.554 26.789 -8.284 1.00 37.38 N ANISOU 1608 N GLY B 478 3950 4768 5486 -1021 -172 631 N ATOM 1609 CA GLY B 478 -10.366 27.957 -8.015 1.00 37.58 C ANISOU 1609 CA GLY B 478 3926 4790 5563 -932 -206 731 C ATOM 1610 C GLY B 478 -9.469 29.047 -7.454 1.00 37.51 C ANISOU 1610 C GLY B 478 3990 4767 5494 -813 -219 607 C ATOM 1611 O GLY B 478 -8.436 29.311 -8.023 1.00 37.68 O ANISOU 1611 O GLY B 478 4078 4789 5451 -923 -272 489 O ATOM 1612 N ARG B 479 -9.828 29.630 -6.311 1.00 32.29 N ANISOU 1612 N ARG B 479 3327 4100 4844 -590 -171 637 N ATOM 1613 CA ARG B 479 -9.044 30.744 -5.744 1.00 43.77 C ANISOU 1613 CA ARG B 479 4882 5519 6228 -482 -203 534 C ATOM 1614 C ARG B 479 -8.659 30.455 -4.294 1.00 52.21 C ANISOU 1614 C ARG B 479 5991 6595 7250 -274 -100 482 C ATOM 1615 O ARG B 479 -8.755 31.327 -3.426 1.00 41.52 O ANISOU 1615 O ARG B 479 4701 5207 5866 -103 -89 474 O ATOM 1616 CB ARG B 479 -9.839 32.057 -5.838 1.00 39.87 C ANISOU 1616 CB ARG B 479 4395 4980 5775 -417 -274 610 C ATOM 1617 CG ARG B 479 -10.066 32.539 -7.314 1.00 42.52 C ANISOU 1617 CG ARG B 479 4709 5298 6149 -650 -409 655 C ATOM 1618 CD ARG B 479 -11.032 33.712 -7.341 1.00 59.24 C ANISOU 1618 CD ARG B 479 6812 7364 8334 -562 -475 758 C ATOM 1619 NE ARG B 479 -11.758 33.809 -8.600 1.00 71.95 N ANISOU 1619 NE ARG B 479 8341 8971 10025 -766 -571 874 N ATOM 1620 CZ ARG B 479 -12.644 34.762 -8.885 1.00 81.93 C ANISOU 1620 CZ ARG B 479 9571 10190 11370 -733 -650 985 C ATOM 1621 NH1 ARG B 479 -13.249 34.758 -10.068 1.00 85.20 N ANISOU 1621 NH1 ARG B 479 9908 10603 11859 -951 -747 1100 N ATOM 1622 NH2 ARG B 479 -12.926 35.714 -7.995 1.00 73.35 N ANISOU 1622 NH2 ARG B 479 8534 9050 10286 -484 -636 984 N ATOM 1623 N ASN B 480 -8.237 29.216 -4.045 1.00 44.69 N ANISOU 1623 N ASN B 480 5014 5677 6288 -295 -31 449 N ATOM 1624 CA ASN B 480 -7.864 28.762 -2.698 1.00 48.45 C ANISOU 1624 CA ASN B 480 5518 6163 6726 -128 61 411 C ATOM 1625 C ASN B 480 -8.898 29.015 -1.622 1.00 42.03 C ANISOU 1625 C ASN B 480 4673 5360 5936 73 138 506 C ATOM 1626 O ASN B 480 -8.555 29.150 -0.445 1.00 39.26 O ANISOU 1626 O ASN B 480 4385 5002 5529 225 195 463 O ATOM 1627 CB ASN B 480 -6.531 29.373 -2.282 1.00 41.86 C ANISOU 1627 CB ASN B 480 4801 5306 5799 -104 25 283 C ATOM 1628 CG ASN B 480 -5.395 28.912 -3.183 1.00 53.45 C ANISOU 1628 CG ASN B 480 6275 6798 7235 -278 -21 191 C ATOM 1629 OD1 ASN B 480 -5.021 27.736 -3.184 1.00 63.32 O ANISOU 1629 OD1 ASN B 480 7488 8072 8497 -307 32 162 O ATOM 1630 ND2 ASN B 480 -4.854 29.824 -3.950 1.00 55.04 N ANISOU 1630 ND2 ASN B 480 6526 6997 7392 -391 -122 146 N ATOM 1631 N ASP B 481 -10.172 29.027 -2.007 1.00 39.45 N ANISOU 1631 N ASP B 481 4242 5059 5687 71 145 646 N ATOM 1632 CA ASP B 481 -11.258 29.117 -1.022 1.00 32.06 C ANISOU 1632 CA ASP B 481 3239 4166 4775 267 239 760 C ATOM 1633 C ASP B 481 -12.439 28.262 -1.410 1.00 39.41 C ANISOU 1633 C ASP B 481 4015 5170 5790 200 262 934 C ATOM 1634 O ASP B 481 -13.595 28.651 -1.200 1.00 39.52 O ANISOU 1634 O ASP B 481 3932 5232 5853 306 300 1075 O ATOM 1635 CB ASP B 481 -11.721 30.565 -0.854 1.00 48.76 C ANISOU 1635 CB ASP B 481 5400 6240 6888 409 221 775 C ATOM 1636 CG ASP B 481 -12.325 31.127 -2.132 1.00 58.89 C ANISOU 1636 CG ASP B 481 6625 7503 8249 280 121 855 C ATOM 1637 OD1 ASP B 481 -12.136 30.512 -3.207 1.00 46.34 O ANISOU 1637 OD1 ASP B 481 4996 5921 6692 55 55 865 O ATOM 1638 OD2 ASP B 481 -12.988 32.178 -2.052 1.00 55.09 O ANISOU 1638 OD2 ASP B 481 6145 6992 7794 406 108 907 O ATOM 1639 N CYS B 482 -12.161 27.088 -1.965 1.00 33.11 N ANISOU 1639 N CYS B 482 3195 4381 5003 28 236 934 N ATOM 1640 CA CYS B 482 -13.242 26.208 -2.397 1.00 44.42 C ANISOU 1640 CA CYS B 482 4504 5872 6501 -73 230 1113 C ATOM 1641 C CYS B 482 -14.092 25.846 -1.191 1.00 48.54 C ANISOU 1641 C CYS B 482 4932 6487 7026 96 330 1237 C ATOM 1642 O CYS B 482 -13.587 25.769 -0.074 1.00 38.49 O ANISOU 1642 O CYS B 482 3711 5221 5694 239 402 1153 O ATOM 1643 CB CYS B 482 -12.677 24.947 -3.088 1.00 38.74 C ANISOU 1643 CB CYS B 482 3825 5123 5770 -273 183 1068 C ATOM 1644 SG CYS B 482 -11.718 25.312 -4.593 1.00 31.96 S ANISOU 1644 SG CYS B 482 3065 4185 4893 -485 81 929 S ATOM 1645 N ILE B 483 -15.392 25.655 -1.405 1.00 43.19 N ANISOU 1645 N ILE B 483 4111 5891 6411 74 332 1448 N ATOM 1646 CA ILE B 483 -16.268 25.213 -0.340 1.00 42.10 C ANISOU 1646 CA ILE B 483 3857 5873 6268 210 424 1594 C ATOM 1647 C ILE B 483 -16.011 23.734 -0.071 1.00 50.35 C ANISOU 1647 C ILE B 483 4911 6936 7282 98 411 1609 C ATOM 1648 O ILE B 483 -16.140 22.911 -0.976 1.00 44.56 O ANISOU 1648 O ILE B 483 4177 6180 6576 -114 322 1673 O ATOM 1649 CB ILE B 483 -17.753 25.404 -0.733 1.00 40.92 C ANISOU 1649 CB ILE B 483 3526 5824 6197 199 419 1848 C ATOM 1650 CG1 ILE B 483 -18.091 26.890 -0.841 1.00 39.49 C ANISOU 1650 CG1 ILE B 483 3329 5623 6053 355 439 1843 C ATOM 1651 CG2 ILE B 483 -18.691 24.653 0.249 1.00 38.39 C ANISOU 1651 CG2 ILE B 483 3060 5664 5863 285 501 2036 C ATOM 1652 CD1 ILE B 483 -19.256 27.151 -1.751 1.00 58.36 C ANISOU 1652 CD1 ILE B 483 5567 8062 8543 265 380 2065 C ATOM 1653 N ILE B 484 -15.645 23.390 1.166 1.00 41.45 N ANISOU 1653 N ILE B 484 3812 5842 6096 231 489 1549 N ATOM 1654 CA ILE B 484 -15.376 22.005 1.509 1.00 41.67 C ANISOU 1654 CA ILE B 484 3857 5879 6097 135 465 1562 C ATOM 1655 C ILE B 484 -16.520 21.476 2.371 1.00 53.67 C ANISOU 1655 C ILE B 484 5229 7555 7609 194 517 1774 C ATOM 1656 O ILE B 484 -16.637 21.804 3.545 1.00 53.73 O ANISOU 1656 O ILE B 484 5209 7637 7570 378 620 1769 O ATOM 1657 CB ILE B 484 -14.060 21.846 2.289 1.00 39.51 C ANISOU 1657 CB ILE B 484 3717 5532 5763 208 494 1356 C ATOM 1658 CG1 ILE B 484 -12.893 22.423 1.493 1.00 45.86 C ANISOU 1658 CG1 ILE B 484 4649 6212 6564 155 447 1161 C ATOM 1659 CG2 ILE B 484 -13.845 20.369 2.627 1.00 37.34 C ANISOU 1659 CG2 ILE B 484 3456 5258 5473 109 454 1383 C ATOM 1660 CD1 ILE B 484 -12.626 21.688 0.175 1.00 37.43 C ANISOU 1660 CD1 ILE B 484 3617 5076 5528 -64 347 1145 C ATOM 1661 N ASP B 485 -17.375 20.669 1.775 1.00 55.79 N ANISOU 1661 N ASP B 485 5407 7879 7912 27 442 1971 N ATOM 1662 CA ASP B 485 -18.517 20.131 2.484 1.00 58.49 C ANISOU 1662 CA ASP B 485 5589 8393 8242 50 472 2208 C ATOM 1663 C ASP B 485 -18.608 18.699 2.049 1.00 55.71 C ANISOU 1663 C ASP B 485 5264 8018 7884 -185 344 2307 C ATOM 1664 O ASP B 485 -17.701 18.200 1.379 0.91 49.42 O ANISOU 1664 O ASP B 485 4623 7068 7087 -312 263 2157 O ATOM 1665 CB ASP B 485 -19.799 20.907 2.161 0.66 64.76 C ANISOU 1665 CB ASP B 485 6203 9311 9090 103 506 2420 C ATOM 1666 CG ASP B 485 -20.252 20.752 0.711 0.54 61.98 C ANISOU 1666 CG ASP B 485 5831 8911 8808 -125 377 2542 C ATOM 1667 OD1 ASP B 485 -19.672 19.965 -0.060 1.00 56.55 O ANISOU 1667 OD1 ASP B 485 5271 8101 8113 -333 264 2474 O ATOM 1668 OD2 ASP B 485 -21.228 21.422 0.340 1.00 68.67 O ANISOU 1668 OD2 ASP B 485 6534 9844 9714 -97 389 2715 O ATOM 1669 N LYS B 486 -19.688 18.029 2.416 1.00 59.72 N ANISOU 1669 N LYS B 486 5631 8679 8380 -244 322 2561 N ATOM 1670 CA LYS B 486 -19.709 16.583 2.307 1.00 59.44 C ANISOU 1670 CA LYS B 486 5651 8619 8314 -450 192 2650 C ATOM 1671 C LYS B 486 -19.590 16.119 0.851 1.00 57.37 C ANISOU 1671 C LYS B 486 5501 8214 8083 -690 47 2655 C ATOM 1672 O LYS B 486 -18.878 15.164 0.571 1.00 67.43 O ANISOU 1672 O LYS B 486 6937 9353 9330 -814 -45 2552 O ATOM 1673 CB LYS B 486 -20.959 15.998 2.977 1.00 67.29 C ANISOU 1673 CB LYS B 486 6462 9828 9278 -486 180 2953 C ATOM 1674 CG LYS B 486 -20.927 14.480 3.074 1.00 80.92 C ANISOU 1674 CG LYS B 486 8266 11525 10956 -690 31 3042 C ATOM 1675 CD LYS B 486 -22.191 13.912 3.722 1.00 90.49 C ANISOU 1675 CD LYS B 486 9285 12972 12125 -752 1 3369 C ATOM 1676 CE LYS B 486 -22.071 12.400 3.967 1.00 98.35 C ANISOU 1676 CE LYS B 486 10383 13927 13060 -951 -164 3444 C ATOM 1677 NZ LYS B 486 -21.902 11.616 2.703 1.00 97.10 N ANISOU 1677 NZ LYS B 486 10399 13583 12913 -1204 -349 3455 N ATOM 1678 N ILE B 487 -20.266 16.779 -0.079 1.00 76.04 N ANISOU 1678 N ILE B 487 7790 10600 10501 -756 26 2771 N ATOM 1679 CA ILE B 487 -20.205 16.329 -1.474 1.00 91.51 C ANISOU 1679 CA ILE B 487 9867 12426 12476 -1007 -115 2788 C ATOM 1680 C ILE B 487 -19.011 16.932 -2.242 1.00 86.03 C ANISOU 1680 C ILE B 487 9335 11557 11796 -992 -97 2498 C ATOM 1681 O ILE B 487 -18.487 16.312 -3.171 1.00 90.83 O ANISOU 1681 O ILE B 487 10105 12022 12384 -1169 -193 2413 O ATOM 1682 CB ILE B 487 -21.503 16.637 -2.258 1.00103.07 C ANISOU 1682 CB ILE B 487 11184 13987 13990 -1145 -179 3078 C ATOM 1683 CG1 ILE B 487 -22.561 17.306 -1.369 1.00101.21 C ANISOU 1683 CG1 ILE B 487 10694 13978 13783 -962 -70 3284 C ATOM 1684 CG2 ILE B 487 -22.042 15.356 -2.900 1.00103.57 C ANISOU 1684 CG2 ILE B 487 11313 14021 14016 -1441 -357 3281 C ATOM 1685 CD1 ILE B 487 -22.405 18.816 -1.265 1.00 93.92 C ANISOU 1685 CD1 ILE B 487 9706 13063 12915 -728 64 3158 C ATOM 1686 N ARG B 488 -18.576 18.124 -1.835 1.00 64.91 N ANISOU 1686 N ARG B 488 6624 8896 9143 -781 22 2349 N ATOM 1687 CA ARG B 488 -17.497 18.840 -2.523 1.00 59.37 C ANISOU 1687 CA ARG B 488 6051 8058 8449 -768 33 2100 C ATOM 1688 C ARG B 488 -16.065 18.675 -1.949 1.00 53.63 C ANISOU 1688 C ARG B 488 5462 7239 7675 -657 85 1827 C ATOM 1689 O ARG B 488 -15.105 19.086 -2.593 1.00 41.28 O ANISOU 1689 O ARG B 488 4007 5573 6105 -678 79 1634 O ATOM 1690 CB ARG B 488 -17.860 20.329 -2.632 1.00 45.66 C ANISOU 1690 CB ARG B 488 4216 6369 6763 -640 96 2113 C ATOM 1691 CG ARG B 488 -19.102 20.594 -3.532 1.00 39.79 C ANISOU 1691 CG ARG B 488 3349 5684 6084 -782 24 2365 C ATOM 1692 CD ARG B 488 -19.547 22.050 -3.532 1.00 55.30 C ANISOU 1692 CD ARG B 488 5206 7696 8110 -627 83 2394 C ATOM 1693 NE ARG B 488 -20.352 22.361 -2.357 1.00 69.47 N ANISOU 1693 NE ARG B 488 6838 9647 9912 -402 195 2528 N ATOM 1694 CZ ARG B 488 -21.017 23.501 -2.174 1.00 70.25 C ANISOU 1694 CZ ARG B 488 6814 9815 10064 -230 260 2608 C ATOM 1695 NH1 ARG B 488 -20.990 24.443 -3.114 1.00 71.45 N ANISOU 1695 NH1 ARG B 488 6986 9886 10276 -276 205 2577 N ATOM 1696 NH2 ARG B 488 -21.720 23.698 -1.054 1.00 55.03 N ANISOU 1696 NH2 ARG B 488 4744 8040 8126 -10 380 2721 N ATOM 1697 N ARG B 489 -15.916 18.072 -0.767 1.00 40.27 N ANISOU 1697 N ARG B 489 3760 5593 5949 -552 129 1823 N ATOM 1698 CA ARG B 489 -14.607 17.880 -0.149 0.66 38.15 C ANISOU 1698 CA ARG B 489 3606 5245 5644 -452 170 1596 C ATOM 1699 C ARG B 489 -13.626 17.095 -1.045 1.00 35.96 C ANISOU 1699 C ARG B 489 3489 4821 5354 -592 92 1445 C ATOM 1700 O ARG B 489 -12.406 17.284 -0.987 0.94 43.51 O ANISOU 1700 O ARG B 489 4536 5703 6295 -524 125 1235 O ATOM 1701 CB ARG B 489 -14.764 17.162 1.221 1.00 40.63 C ANISOU 1701 CB ARG B 489 3878 5635 5925 -364 202 1659 C ATOM 1702 CG ARG B 489 -15.127 15.690 1.096 1.00 46.58 C ANISOU 1702 CG ARG B 489 4663 6372 6665 -531 90 1784 C ATOM 1703 CD ARG B 489 -15.664 15.111 2.416 1.00 59.95 C ANISOU 1703 CD ARG B 489 6267 8186 8325 -470 109 1920 C ATOM 1704 NE ARG B 489 -16.048 13.713 2.257 1.00 62.16 N ANISOU 1704 NE ARG B 489 6589 8444 8585 -652 -27 2056 N ATOM 1705 CZ ARG B 489 -16.820 13.043 3.112 0.70 62.50 C ANISOU 1705 CZ ARG B 489 6542 8612 8595 -680 -59 2250 C ATOM 1706 NH1 ARG B 489 -17.300 13.646 4.179 1.00 47.25 N ANISOU 1706 NH1 ARG B 489 4464 6846 6643 -527 54 2324 N ATOM 1707 NH2 ARG B 489 -17.120 11.771 2.894 1.00 57.22 N ANISOU 1707 NH2 ARG B 489 5938 7903 7900 -865 -210 2373 N ATOM 1708 N LYS B 490 -14.142 16.169 -1.836 1.00 30.44 N ANISOU 1708 N LYS B 490 2830 4081 4653 -784 -11 1558 N ATOM 1709 CA LYS B 490 -13.316 15.481 -2.824 1.00 37.43 C ANISOU 1709 CA LYS B 490 3883 4823 5517 -914 -77 1417 C ATOM 1710 C LYS B 490 -12.822 16.404 -3.948 1.00 46.23 C ANISOU 1710 C LYS B 490 5039 5890 6637 -962 -64 1291 C ATOM 1711 O LYS B 490 -11.845 16.068 -4.605 1.00 38.22 O ANISOU 1711 O LYS B 490 4153 4776 5594 -1010 -76 1119 O ATOM 1712 CB LYS B 490 -14.090 14.358 -3.524 1.00 55.54 C ANISOU 1712 CB LYS B 490 6242 7071 7791 -1131 -205 1581 C ATOM 1713 CG LYS B 490 -14.900 13.443 -2.632 1.00 73.93 C ANISOU 1713 CG LYS B 490 8515 9467 10106 -1151 -259 1779 C ATOM 1714 CD LYS B 490 -15.335 12.195 -3.401 1.00 91.15 C ANISOU 1714 CD LYS B 490 10832 11554 12248 -1383 -414 1894 C ATOM 1715 CE LYS B 490 -16.110 11.223 -2.502 1.00109.00 C ANISOU 1715 CE LYS B 490 13047 13884 14483 -1426 -495 2105 C ATOM 1716 NZ LYS B 490 -16.132 9.824 -3.033 1.00117.65 N ANISOU 1716 NZ LYS B 490 14341 14837 15523 -1619 -658 2150 N ATOM 1717 N ASN B 491 -13.502 17.519 -4.230 0.74 32.52 N ANISOU 1717 N ASN B 491 3196 4224 4934 -959 -47 1382 N ATOM 1718 CA ASN B 491 -13.117 18.321 -5.415 1.00 38.65 C ANISOU 1718 CA ASN B 491 4020 4953 5714 -1052 -66 1285 C ATOM 1719 C ASN B 491 -11.719 18.894 -5.241 1.00 36.54 C ANISOU 1719 C ASN B 491 3814 4651 5420 -931 -1 1039 C ATOM 1720 O ASN B 491 -10.921 18.901 -6.173 1.00 37.90 O ANISOU 1720 O ASN B 491 4081 4760 5561 -1024 -21 900 O ATOM 1721 CB ASN B 491 -14.056 19.523 -5.694 1.00 31.37 C ANISOU 1721 CB ASN B 491 2970 4105 4844 -1054 -69 1425 C ATOM 1722 CG ASN B 491 -15.468 19.125 -6.094 1.00 43.42 C ANISOU 1722 CG ASN B 491 4414 5680 6404 -1204 -145 1697 C ATOM 1723 OD1 ASN B 491 -16.190 19.914 -6.721 0.77 44.41 O ANISOU 1723 OD1 ASN B 491 4459 5838 6577 -1273 -179 1818 O ATOM 1724 ND2 ASN B 491 -15.883 17.933 -5.716 1.00 39.64 N ANISOU 1724 ND2 ASN B 491 3948 5210 5903 -1260 -183 1812 N ATOM 1725 N CYS B 492 -11.427 19.423 -4.059 1.00 37.81 N ANISOU 1725 N CYS B 492 3920 4862 5583 -732 76 995 N ATOM 1726 CA CYS B 492 -10.188 20.199 -3.906 1.00 30.57 C ANISOU 1726 CA CYS B 492 3051 3925 4637 -633 121 797 C ATOM 1727 C CYS B 492 -9.366 19.791 -2.710 1.00 27.51 C ANISOU 1727 C CYS B 492 2689 3537 4228 -481 178 703 C ATOM 1728 O CYS B 492 -9.499 20.373 -1.630 1.00 31.65 O ANISOU 1728 O CYS B 492 3166 4111 4749 -330 232 725 O ATOM 1729 CB CYS B 492 -10.457 21.715 -3.859 1.00 33.21 C ANISOU 1729 CB CYS B 492 3330 4303 4985 -560 136 813 C ATOM 1730 SG CYS B 492 -8.901 22.625 -4.101 1.00 31.91 S ANISOU 1730 SG CYS B 492 3252 4105 4767 -529 140 589 S ATOM 1731 N PRO B 493 -8.496 18.786 -2.884 1.00 37.27 N ANISOU 1731 N PRO B 493 4006 4709 5444 -517 166 597 N ATOM 1732 CA PRO B 493 -7.638 18.351 -1.766 1.00 36.56 C ANISOU 1732 CA PRO B 493 3937 4611 5343 -383 208 513 C ATOM 1733 C PRO B 493 -6.776 19.487 -1.234 1.00 38.19 C ANISOU 1733 C PRO B 493 4141 4845 5523 -266 254 408 C ATOM 1734 O PRO B 493 -6.460 19.507 -0.038 1.00 37.84 O ANISOU 1734 O PRO B 493 4090 4818 5469 -142 292 398 O ATOM 1735 CB PRO B 493 -6.755 17.275 -2.395 1.00 38.79 C ANISOU 1735 CB PRO B 493 4312 4812 5614 -447 182 399 C ATOM 1736 CG PRO B 493 -7.563 16.742 -3.535 1.00 44.67 C ANISOU 1736 CG PRO B 493 5096 5517 6360 -618 119 478 C ATOM 1737 CD PRO B 493 -8.509 17.815 -3.992 1.00 40.02 C ANISOU 1737 CD PRO B 493 4434 4988 5784 -680 107 588 C ATOM 1738 N ALA B 494 -6.413 20.418 -2.114 1.00 32.98 N ANISOU 1738 N ALA B 494 3497 4189 4844 -322 238 341 N ATOM 1739 CA ALA B 494 -5.594 21.561 -1.726 1.00 29.67 C ANISOU 1739 CA ALA B 494 3094 3792 4386 -241 255 254 C ATOM 1740 C ALA B 494 -6.328 22.342 -0.640 0.75 29.60 C ANISOU 1740 C ALA B 494 3054 3816 4376 -111 287 340 C ATOM 1741 O ALA B 494 -5.774 22.652 0.392 1.00 28.68 O ANISOU 1741 O ALA B 494 2968 3704 4226 3 318 299 O ATOM 1742 CB ALA B 494 -5.313 22.482 -2.929 1.00 27.22 C ANISOU 1742 CB ALA B 494 2801 3488 4052 -352 209 200 C ATOM 1743 N CYS B 495 -7.577 22.682 -0.900 1.00 25.22 N ANISOU 1743 N CYS B 495 2442 3286 3853 -128 282 464 N ATOM 1744 CA CYS B 495 -8.324 23.506 0.027 1.00 29.79 C ANISOU 1744 CA CYS B 495 2990 3903 4426 15 326 542 C ATOM 1745 C CYS B 495 -8.744 22.664 1.254 1.00 37.57 C ANISOU 1745 C CYS B 495 3937 4927 5411 112 385 617 C ATOM 1746 O CYS B 495 -8.870 23.172 2.335 1.00 37.49 O ANISOU 1746 O CYS B 495 3934 4943 5366 254 441 627 O ATOM 1747 CB CYS B 495 -9.542 24.064 -0.686 1.00 26.61 C ANISOU 1747 CB CYS B 495 2515 3526 4068 -29 303 668 C ATOM 1748 SG CYS B 495 -9.212 25.556 -1.700 1.00 31.96 S ANISOU 1748 SG CYS B 495 3243 4164 4735 -88 232 598 S ATOM 1749 N ARG B 496 -8.981 21.378 1.055 1.00 37.60 N ANISOU 1749 N ARG B 496 3911 4931 5445 23 364 671 N ATOM 1750 CA ARG B 496 -9.366 20.500 2.136 1.00 31.79 C ANISOU 1750 CA ARG B 496 3139 4234 4706 81 395 752 C ATOM 1751 C ARG B 496 -8.220 20.421 3.139 0.82 32.37 C ANISOU 1751 C ARG B 496 3282 4277 4739 172 423 633 C ATOM 1752 O ARG B 496 -8.417 20.581 4.332 1.00 31.54 O ANISOU 1752 O ARG B 496 3168 4214 4601 284 475 668 O ATOM 1753 CB ARG B 496 -9.715 19.100 1.614 1.00 27.72 C ANISOU 1753 CB ARG B 496 2611 3700 4223 -57 334 825 C ATOM 1754 CG ARG B 496 -10.372 18.217 2.701 1.00 30.62 C ANISOU 1754 CG ARG B 496 2923 4127 4584 -22 345 954 C ATOM 1755 CD ARG B 496 -10.561 16.795 2.223 1.00 48.88 C ANISOU 1755 CD ARG B 496 5261 6395 6916 -168 257 1015 C ATOM 1756 NE ARG B 496 -11.413 16.010 3.106 1.00 36.69 N ANISOU 1756 NE ARG B 496 3651 4928 5363 -172 242 1180 N ATOM 1757 CZ ARG B 496 -11.828 14.776 2.829 1.00 46.48 C ANISOU 1757 CZ ARG B 496 4911 6141 6608 -307 146 1282 C ATOM 1758 NH1 ARG B 496 -11.454 14.189 1.694 1.00 42.75 N ANISOU 1758 NH1 ARG B 496 4541 5553 6148 -434 68 1219 N ATOM 1759 NH2 ARG B 496 -12.608 14.129 3.690 1.00 48.63 N ANISOU 1759 NH2 ARG B 496 5114 6503 6861 -320 122 1447 N ATOM 1760 N TYR B 497 -7.010 20.236 2.628 1.00 29.42 N ANISOU 1760 N TYR B 497 2977 3838 4364 120 388 498 N ATOM 1761 CA TYR B 497 -5.828 20.125 3.456 1.00 34.08 C ANISOU 1761 CA TYR B 497 3623 4399 4925 185 399 400 C ATOM 1762 C TYR B 497 -5.605 21.457 4.175 0.90 37.69 C ANISOU 1762 C TYR B 497 4124 4874 5323 292 435 369 C ATOM 1763 O TYR B 497 -5.274 21.497 5.358 1.00 34.24 O ANISOU 1763 O TYR B 497 3722 4441 4848 375 464 364 O ATOM 1764 CB TYR B 497 -4.594 19.774 2.598 1.00 26.00 C ANISOU 1764 CB TYR B 497 2643 3323 3913 113 361 273 C ATOM 1765 CG TYR B 497 -3.341 19.669 3.432 1.00 26.97 C ANISOU 1765 CG TYR B 497 2805 3427 4015 176 366 194 C ATOM 1766 CD1 TYR B 497 -3.229 18.674 4.413 1.00 30.55 C ANISOU 1766 CD1 TYR B 497 3254 3864 4489 215 367 227 C ATOM 1767 CD2 TYR B 497 -2.275 20.552 3.251 1.00 27.64 C ANISOU 1767 CD2 TYR B 497 2928 3516 4059 181 356 105 C ATOM 1768 CE1 TYR B 497 -2.104 18.561 5.191 1.00 35.16 C ANISOU 1768 CE1 TYR B 497 3867 4429 5063 261 362 173 C ATOM 1769 CE2 TYR B 497 -1.133 20.450 4.030 0.99 32.09 C ANISOU 1769 CE2 TYR B 497 3518 4070 4603 225 351 60 C ATOM 1770 CZ TYR B 497 -1.061 19.456 5.010 1.00 37.64 C ANISOU 1770 CZ TYR B 497 4213 4751 5338 268 356 96 C ATOM 1771 OH TYR B 497 0.059 19.344 5.808 1.00 35.14 O ANISOU 1771 OH TYR B 497 3918 4423 5012 301 342 68 O ATOM 1772 N ARG B 498 -5.781 22.550 3.450 1.00 31.80 N ANISOU 1772 N ARG B 498 3391 4128 4563 279 422 351 N ATOM 1773 CA ARG B 498 -5.645 23.858 4.057 1.00 30.58 C ANISOU 1773 CA ARG B 498 3307 3969 4343 378 438 324 C ATOM 1774 C ARG B 498 -6.623 24.008 5.224 1.00 30.23 C ANISOU 1774 C ARG B 498 3245 3966 4273 512 512 415 C ATOM 1775 O ARG B 498 -6.242 24.442 6.289 0.96 34.12 O ANISOU 1775 O ARG B 498 3819 4447 4698 606 542 385 O ATOM 1776 CB ARG B 498 -5.866 24.988 3.015 1.00 27.54 C ANISOU 1776 CB ARG B 498 2937 3571 3956 336 394 309 C ATOM 1777 CG ARG B 498 -6.079 26.356 3.714 1.00 40.86 C ANISOU 1777 CG ARG B 498 4710 5239 5574 464 408 306 C ATOM 1778 CD ARG B 498 -6.338 27.478 2.701 1.00 46.82 C ANISOU 1778 CD ARG B 498 5486 5969 6334 421 345 299 C ATOM 1779 NE ARG B 498 -7.467 27.157 1.829 1.00 57.83 N ANISOU 1779 NE ARG B 498 6762 7399 7813 363 348 396 N ATOM 1780 CZ ARG B 498 -8.749 27.216 2.195 1.00 65.41 C ANISOU 1780 CZ ARG B 498 7647 8400 8806 463 409 515 C ATOM 1781 NH1 ARG B 498 -9.090 27.591 3.431 1.00 61.26 N ANISOU 1781 NH1 ARG B 498 7156 7888 8230 641 486 535 N ATOM 1782 NH2 ARG B 498 -9.696 26.899 1.312 1.00 57.76 N ANISOU 1782 NH2 ARG B 498 6565 7465 7914 378 393 621 N ATOM 1783 N LYS B 499 -7.881 23.636 5.042 1.00 29.16 N ANISOU 1783 N LYS B 499 3007 3889 4184 516 543 536 N ATOM 1784 CA LYS B 499 -8.834 23.719 6.152 1.00 38.03 C ANISOU 1784 CA LYS B 499 4090 5082 5275 648 628 634 C ATOM 1785 C LYS B 499 -8.433 22.832 7.328 0.79 34.62 C ANISOU 1785 C LYS B 499 3676 4668 4812 669 653 634 C ATOM 1786 O LYS B 499 -8.686 23.197 8.486 1.00 38.67 O ANISOU 1786 O LYS B 499 4222 5216 5256 790 724 655 O ATOM 1787 CB LYS B 499 -10.235 23.309 5.723 1.00 36.27 C ANISOU 1787 CB LYS B 499 3725 4945 5111 625 647 794 C ATOM 1788 CG LYS B 499 -11.019 24.406 5.106 0.69 50.67 C ANISOU 1788 CG LYS B 499 5515 6782 6954 677 658 841 C ATOM 1789 CD LYS B 499 -12.434 23.969 4.882 1.00 56.18 C ANISOU 1789 CD LYS B 499 6052 7586 7705 663 682 1032 C ATOM 1790 CE LYS B 499 -13.340 24.425 6.003 1.00 53.09 C ANISOU 1790 CE LYS B 499 5603 7298 7269 857 798 1125 C ATOM 1791 NZ LYS B 499 -14.736 23.979 5.765 1.00 40.97 N ANISOU 1791 NZ LYS B 499 3884 5896 5788 836 819 1341 N ATOM 1792 N CYS B 500 -7.842 21.668 7.040 1.00 32.73 N ANISOU 1792 N CYS B 500 3420 4398 4617 553 596 614 N ATOM 1793 CA CYS B 500 -7.373 20.763 8.100 1.00 32.39 C ANISOU 1793 CA CYS B 500 3395 4357 4557 556 596 615 C ATOM 1794 C CYS B 500 -6.328 21.505 8.901 1.00 36.88 C ANISOU 1794 C CYS B 500 4083 4875 5054 623 607 514 C ATOM 1795 O CYS B 500 -6.360 21.507 10.137 1.00 32.82 O ANISOU 1795 O CYS B 500 3605 4385 4480 690 650 538 O ATOM 1796 CB CYS B 500 -6.731 19.477 7.523 1.00 32.99 C ANISOU 1796 CB CYS B 500 3459 4378 4699 433 518 586 C ATOM 1797 SG CYS B 500 -7.900 18.252 6.853 1.00 33.55 S ANISOU 1797 SG CYS B 500 3429 4487 4831 323 474 727 S ATOM 1798 N LEU B 501 -5.377 22.129 8.209 1.00 28.63 N ANISOU 1798 N LEU B 501 3105 3766 4007 588 561 411 N ATOM 1799 CA LEU B 501 -4.314 22.846 8.920 1.00 27.66 C ANISOU 1799 CA LEU B 501 3104 3595 3809 625 548 334 C ATOM 1800 C LEU B 501 -4.904 23.988 9.743 1.00 44.99 C ANISOU 1800 C LEU B 501 5385 5801 5909 751 609 352 C ATOM 1801 O LEU B 501 -4.495 24.242 10.862 1.00 42.47 O ANISOU 1801 O LEU B 501 5165 5461 5509 800 626 338 O ATOM 1802 CB LEU B 501 -3.271 23.395 7.955 1.00 31.23 C ANISOU 1802 CB LEU B 501 3600 4001 4264 554 479 242 C ATOM 1803 CG LEU B 501 -2.347 22.312 7.372 1.00 32.53 C ANISOU 1803 CG LEU B 501 3710 4150 4499 459 431 201 C ATOM 1804 CD1 LEU B 501 -1.382 22.957 6.348 1.00 32.43 C ANISOU 1804 CD1 LEU B 501 3723 4124 4474 390 376 119 C ATOM 1805 CD2 LEU B 501 -1.580 21.533 8.499 0.69 28.07 C ANISOU 1805 CD2 LEU B 501 3165 3567 3932 468 422 207 C ATOM 1806 N GLN B 502 -5.887 24.655 9.176 1.00 37.24 N ANISOU 1806 N GLN B 502 4368 4845 4936 804 641 386 N ATOM 1807 CA GLN B 502 -6.383 25.876 9.747 1.00 46.92 C ANISOU 1807 CA GLN B 502 5691 6062 6074 942 693 384 C ATOM 1808 C GLN B 502 -7.247 25.551 10.974 1.00 56.47 C ANISOU 1808 C GLN B 502 6873 7346 7236 1054 799 463 C ATOM 1809 O GLN B 502 -7.358 26.361 11.890 1.00 42.46 O ANISOU 1809 O GLN B 502 5222 5555 5357 1178 855 442 O ATOM 1810 CB GLN B 502 -7.166 26.626 8.687 1.00 47.58 C ANISOU 1810 CB GLN B 502 5728 6151 6201 964 687 406 C ATOM 1811 CG GLN B 502 -7.371 28.091 8.977 1.00 74.45 C ANISOU 1811 CG GLN B 502 9269 9499 9518 1097 701 370 C ATOM 1812 CD GLN B 502 -7.309 28.931 7.709 1.00 84.97 C ANISOU 1812 CD GLN B 502 10615 10781 10889 1039 615 338 C ATOM 1813 OE1 GLN B 502 -6.895 30.093 7.746 1.00 90.24 O ANISOU 1813 OE1 GLN B 502 11439 11365 11481 1080 562 275 O ATOM 1814 NE2 GLN B 502 -7.711 28.344 6.578 1.00 62.28 N ANISOU 1814 NE2 GLN B 502 7590 7951 8123 929 587 388 N ATOM 1815 N ALA B 503 -7.836 24.357 11.011 1.00 45.61 N ANISOU 1815 N ALA B 503 5349 6055 5925 1004 821 555 N ATOM 1816 CA ALA B 503 -8.615 23.959 12.179 1.00 45.49 C ANISOU 1816 CA ALA B 503 5293 6136 5857 1086 913 642 C ATOM 1817 C ALA B 503 -7.680 23.461 13.274 1.00 40.25 C ANISOU 1817 C ALA B 503 4722 5436 5135 1046 893 601 C ATOM 1818 O ALA B 503 -8.109 23.202 14.374 0.90 41.90 O ANISOU 1818 O ALA B 503 4930 5714 5277 1098 960 656 O ATOM 1819 CB ALA B 503 -9.653 22.879 11.821 1.00 32.58 C ANISOU 1819 CB ALA B 503 3464 4615 4301 1027 921 783 C ATOM 1820 N GLY B 504 -6.400 23.304 12.956 0.97 38.06 N ANISOU 1820 N GLY B 504 4515 5063 4885 945 797 515 N ATOM 1821 CA GLY B 504 -5.423 22.914 13.947 1.00 36.22 C ANISOU 1821 CA GLY B 504 4371 4786 4606 898 764 486 C ATOM 1822 C GLY B 504 -5.018 21.446 13.941 1.00 49.96 C ANISOU 1822 C GLY B 504 6015 6532 6436 779 699 521 C ATOM 1823 O GLY B 504 -4.367 20.996 14.884 1.00 36.86 O ANISOU 1823 O GLY B 504 4407 4850 4748 740 672 524 O ATOM 1824 N MET B 505 -5.366 20.680 12.903 1.00 36.85 N ANISOU 1824 N MET B 505 4230 4890 4880 714 663 551 N ATOM 1825 CA MET B 505 -5.056 19.242 12.949 1.00 32.57 C ANISOU 1825 CA MET B 505 3621 4338 4416 613 594 585 C ATOM 1826 C MET B 505 -3.570 19.044 12.994 1.00 33.62 C ANISOU 1826 C MET B 505 3822 4378 4575 561 521 501 C ATOM 1827 O MET B 505 -2.822 19.761 12.343 1.00 32.30 O ANISOU 1827 O MET B 505 3704 4163 4406 561 502 420 O ATOM 1828 CB MET B 505 -5.663 18.467 11.774 1.00 35.97 C ANISOU 1828 CB MET B 505 3944 4783 4940 546 558 628 C ATOM 1829 CG MET B 505 -7.187 18.584 11.762 1.00 37.19 C ANISOU 1829 CG MET B 505 4006 5050 5074 583 620 750 C ATOM 1830 SD MET B 505 -7.904 17.633 10.417 0.90 35.60 S ANISOU 1830 SD MET B 505 3700 4856 4968 469 552 826 S ATOM 1831 CE MET B 505 -7.553 15.957 10.966 1.00 33.87 C ANISOU 1831 CE MET B 505 3475 4605 4787 364 454 872 C ATOM 1832 N ASN B 506 -3.126 18.058 13.774 1.00 33.65 N ANISOU 1832 N ASN B 506 3820 4364 4604 510 473 533 N ATOM 1833 CA ASN B 506 -1.697 17.784 13.825 1.00 38.72 C ANISOU 1833 CA ASN B 506 4503 4925 5286 465 400 473 C ATOM 1834 C ASN B 506 -1.519 16.397 14.383 1.00 39.72 C ANISOU 1834 C ASN B 506 4585 5029 5479 403 333 527 C ATOM 1835 O ASN B 506 -2.319 15.956 15.216 1.00 40.48 O ANISOU 1835 O ASN B 506 4661 5179 5542 390 345 614 O ATOM 1836 CB ASN B 506 -0.987 18.820 14.699 1.00 50.71 C ANISOU 1836 CB ASN B 506 6143 6421 6704 489 412 447 C ATOM 1837 CG ASN B 506 -1.401 18.727 16.159 1.00 53.39 C ANISOU 1837 CG ASN B 506 6534 6791 6961 495 440 516 C ATOM 1838 OD1 ASN B 506 -0.642 18.229 16.973 1.00 48.95 O ANISOU 1838 OD1 ASN B 506 6003 6192 6405 436 383 540 O ATOM 1839 ND2 ASN B 506 -2.620 19.163 16.481 1.00 42.01 N ANISOU 1839 ND2 ASN B 506 5091 5427 5445 565 531 557 N ATOM 1840 N LEU B 507 -0.479 15.713 13.932 1.00 40.12 N ANISOU 1840 N LEU B 507 4617 5007 5618 368 261 482 N ATOM 1841 CA LEU B 507 -0.340 14.303 14.222 1.00 56.11 C ANISOU 1841 CA LEU B 507 6602 6989 7727 317 180 526 C ATOM 1842 C LEU B 507 -0.117 14.080 15.717 1.00 65.87 C ANISOU 1842 C LEU B 507 7875 8228 8925 282 148 595 C ATOM 1843 O LEU B 507 -0.656 13.142 16.289 1.00 67.24 O ANISOU 1843 O LEU B 507 8020 8412 9116 232 100 674 O ATOM 1844 CB LEU B 507 0.804 13.702 13.413 1.00 49.00 C ANISOU 1844 CB LEU B 507 5682 6006 6929 317 122 452 C ATOM 1845 CG LEU B 507 0.486 13.491 11.940 0.65 57.33 C ANISOU 1845 CG LEU B 507 6707 7049 8029 327 136 393 C ATOM 1846 CD1 LEU B 507 1.513 12.550 11.354 1.00 55.85 C ANISOU 1846 CD1 LEU B 507 6504 6775 7941 338 78 332 C ATOM 1847 CD2 LEU B 507 -0.926 12.950 11.747 0.96 49.85 C ANISOU 1847 CD2 LEU B 507 5737 6131 7074 290 131 467 C ATOM 1848 N GLU B 508 0.646 14.960 16.351 1.00 62.31 N ANISOU 1848 N GLU B 508 7495 7769 8411 291 164 575 N ATOM 1849 CA GLU B 508 1.007 14.774 17.749 1.00 76.37 C ANISOU 1849 CA GLU B 508 9327 9538 10150 238 123 640 C ATOM 1850 C GLU B 508 -0.047 15.282 18.729 1.00 72.60 C ANISOU 1850 C GLU B 508 8901 9144 9541 245 197 698 C ATOM 1851 O GLU B 508 0.237 15.425 19.908 1.00 79.25 O ANISOU 1851 O GLU B 508 9816 9983 10312 201 183 741 O ATOM 1852 CB GLU B 508 2.362 15.424 18.025 1.00 80.45 C ANISOU 1852 CB GLU B 508 9911 10005 10652 222 90 613 C ATOM 1853 CG GLU B 508 3.549 14.766 17.287 1.00 88.98 C ANISOU 1853 CG GLU B 508 10920 11022 11867 217 15 579 C ATOM 1854 CD GLU B 508 3.435 13.235 17.119 1.00106.60 C ANISOU 1854 CD GLU B 508 13068 13206 14227 201 -56 602 C ATOM 1855 OE1 GLU B 508 2.317 12.703 16.946 1.00107.29 O ANISOU 1855 OE1 GLU B 508 13131 13319 14315 199 -43 623 O ATOM 1856 OE2 GLU B 508 4.485 12.554 17.133 1.00108.83 O ANISOU 1856 OE2 GLU B 508 13313 13425 14612 192 -133 608 O ATOM 1857 N ALA B 509 -1.265 15.518 18.242 1.00 48.81 N ANISOU 1857 N ALA B 509 5843 6209 6495 300 276 707 N ATOM 1858 CA ALA B 509 -2.347 16.038 19.072 1.00 54.30 C ANISOU 1858 CA ALA B 509 6564 7004 7061 337 369 763 C ATOM 1859 C ALA B 509 -2.597 15.171 20.312 1.00 74.56 C ANISOU 1859 C ALA B 509 9120 9613 9598 253 328 862 C ATOM 1860 O ALA B 509 -2.586 15.692 21.425 1.00 81.29 O ANISOU 1860 O ALA B 509 10063 10492 10331 251 371 882 O ATOM 1861 CB ALA B 509 -3.636 16.174 18.276 1.00 52.69 C ANISOU 1861 CB ALA B 509 6272 6890 6858 399 443 789 C ATOM 1862 N ARG B 510 -2.843 13.872 20.128 1.00 78.26 N ANISOU 1862 N ARG B 510 9491 10082 10160 176 237 927 N ATOM 1863 CA ARG B 510 -3.215 13.007 21.256 1.00 91.63 C ANISOU 1863 CA ARG B 510 11164 11829 11821 78 181 1036 C ATOM 1864 C ARG B 510 -2.087 12.902 22.277 1.00 98.34 C ANISOU 1864 C ARG B 510 12102 12598 12664 3 108 1035 C ATOM 1865 O ARG B 510 -2.328 12.888 23.485 1.00102.30 O ANISOU 1865 O ARG B 510 12646 13158 13066 -56 117 1102 O ATOM 1866 CB ARG B 510 -3.598 11.604 20.779 1.00 86.51 C ANISOU 1866 CB ARG B 510 10418 11172 11280 -4 63 1107 C ATOM 1867 CG ARG B 510 -4.139 10.691 21.891 1.00 75.21 C ANISOU 1867 CG ARG B 510 8955 9817 9805 -124 -11 1241 C ATOM 1868 CD ARG B 510 -3.995 9.215 21.513 1.00 69.89 C ANISOU 1868 CD ARG B 510 8238 9060 9258 -226 -187 1293 C ATOM 1869 NE ARG B 510 -5.125 8.415 21.982 1.00 71.18 N ANISOU 1869 NE ARG B 510 8331 9345 9368 -330 -245 1444 N ATOM 1870 CZ ARG B 510 -5.559 7.304 21.390 1.00 75.80 C ANISOU 1870 CZ ARG B 510 8875 9902 10023 -409 -376 1515 C ATOM 1871 NH1 ARG B 510 -4.966 6.849 20.288 1.00 62.98 N ANISOU 1871 NH1 ARG B 510 7282 8123 8525 -380 -449 1431 N ATOM 1872 NH2 ARG B 510 -6.598 6.648 21.897 1.00 79.26 N ANISOU 1872 NH2 ARG B 510 9248 10472 10394 -522 -438 1675 N ATOM 1873 N LYS B 511 -0.857 12.824 21.781 1.00107.04 N ANISOU 1873 N LYS B 511 13227 13574 13870 1 36 968 N ATOM 1874 CA LYS B 511 0.314 12.709 22.639 1.00112.12 C ANISOU 1874 CA LYS B 511 13938 14135 14527 -77 -48 984 C ATOM 1875 C LYS B 511 0.606 14.027 23.366 1.00110.92 C ANISOU 1875 C LYS B 511 13924 13994 14225 -58 32 959 C ATOM 1876 O LYS B 511 1.220 14.033 24.431 1.00116.62 O ANISOU 1876 O LYS B 511 14728 14682 14901 -149 -22 1007 O ATOM 1877 CB LYS B 511 1.519 12.260 21.809 1.00115.39 C ANISOU 1877 CB LYS B 511 14314 14433 15098 -67 -138 932 C ATOM 1878 CG LYS B 511 1.226 11.035 20.956 1.00122.49 C ANISOU 1878 CG LYS B 511 15114 15296 16129 -64 -210 933 C ATOM 1879 CD LYS B 511 2.464 10.192 20.720 1.00129.36 C ANISOU 1879 CD LYS B 511 15955 16044 17152 -79 -330 920 C ATOM 1880 CE LYS B 511 3.369 10.794 19.667 1.00130.11 C ANISOU 1880 CE LYS B 511 16037 16101 17297 12 -286 820 C ATOM 1881 NZ LYS B 511 4.573 9.948 19.452 1.00129.12 N ANISOU 1881 NZ LYS B 511 15865 15873 17321 20 -389 814 N ATOM 1882 N THR B 512 0.152 15.136 22.784 1.00 89.28 N ANISOU 1882 N THR B 512 11223 11292 11407 53 150 890 N ATOM 1883 CA THR B 512 0.284 16.460 23.391 1.00 88.39 C ANISOU 1883 CA THR B 512 11270 11178 11134 89 227 857 C ATOM 1884 C THR B 512 -0.741 16.671 24.516 1.00 96.82 C ANISOU 1884 C THR B 512 12398 12345 12045 95 318 909 C ATOM 1885 O THR B 512 -0.430 17.277 25.539 1.00104.88 O ANISOU 1885 O THR B 512 13575 13344 12931 59 334 917 O ATOM 1886 CB THR B 512 0.126 17.586 22.325 1.00 75.67 C ANISOU 1886 CB THR B 512 9688 9564 9497 213 309 764 C ATOM 1887 OG1 THR B 512 1.367 17.778 21.623 1.00 62.00 O ANISOU 1887 OG1 THR B 512 7965 7745 7848 189 230 718 O ATOM 1888 CG2 THR B 512 -0.301 18.901 22.973 1.00 77.56 C ANISOU 1888 CG2 THR B 512 10097 9824 9548 285 413 736 C ATOM 1889 N LYS B 513 -1.962 16.181 24.322 1.00101.00 N ANISOU 1889 N LYS B 513 12806 12990 12580 134 377 951 N ATOM 1890 CA LYS B 513 -2.985 16.236 25.361 1.00109.14 C ANISOU 1890 CA LYS B 513 13853 14149 13465 140 468 1017 C ATOM 1891 C LYS B 513 -2.613 15.324 26.530 1.00121.05 C ANISOU 1891 C LYS B 513 15377 15656 14962 -25 366 1106 C ATOM 1892 O LYS B 513 -3.036 15.555 27.664 1.00125.28 O ANISOU 1892 O LYS B 513 15989 16267 15343 -52 429 1148 O ATOM 1893 CB LYS B 513 -4.352 15.845 24.789 1.00109.58 C ANISOU 1893 CB LYS B 513 13744 14347 13543 204 537 1071 C ATOM 1894 CG LYS B 513 -5.186 14.945 25.695 1.00113.04 C ANISOU 1894 CG LYS B 513 14097 14927 13927 114 528 1200 C ATOM 1895 CD LYS B 513 -6.614 14.812 25.194 1.00113.37 C ANISOU 1895 CD LYS B 513 13984 15137 13956 188 615 1274 C ATOM 1896 CE LYS B 513 -7.407 16.075 25.472 1.00113.79 C ANISOU 1896 CE LYS B 513 14088 15294 13852 360 813 1243 C ATOM 1897 NZ LYS B 513 -8.814 15.959 25.017 1.00117.36 N ANISOU 1897 NZ LYS B 513 14365 15930 14296 435 900 1340 N ATOM 1898 N LYS B 514 -1.814 14.294 26.247 1.00141.05 N ANISOU 1898 N LYS B 514 17840 18098 17656 -132 208 1133 N ATOM 1899 CA LYS B 514 -1.340 13.366 27.274 1.00145.40 C ANISOU 1899 CA LYS B 514 18398 18621 18225 -300 80 1222 C ATOM 1900 C LYS B 514 -0.137 13.938 28.027 1.00151.55 C ANISOU 1900 C LYS B 514 19339 19290 18955 -371 33 1206 C ATOM 1901 O LYS B 514 0.553 13.223 28.752 1.00158.32 O ANISOU 1901 O LYS B 514 20206 20087 19859 -518 -99 1278 O ATOM 1902 CB LYS B 514 -0.978 12.013 26.655 1.00139.01 C ANISOU 1902 CB LYS B 514 17459 17744 17615 -371 -79 1260 C ATOM 1903 N LYS B 515 0.117 15.229 27.828 1.00136.25 N ANISOU 1903 N LYS B 515 17530 17318 16922 -274 126 1123 N ATOM 1904 CA LYS B 515 1.073 15.974 28.636 1.00134.48 C ANISOU 1904 CA LYS B 515 17496 17004 16596 -347 94 1122 C ATOM 1905 C LYS B 515 0.350 17.194 29.198 1.00140.20 C ANISOU 1905 C LYS B 515 18392 17784 17092 -255 252 1075 C ATOM 1906 O LYS B 515 0.622 18.328 28.808 1.00137.11 O ANISOU 1906 O LYS B 515 18128 17335 16632 -164 304 996 O ATOM 1907 CB LYS B 515 2.273 16.393 27.805 1.00129.08 C ANISOU 1907 CB LYS B 515 16831 16203 16012 -330 23 1073 C ATOM 1908 N ILE B 516 -0.588 16.942 30.106 1.00158.17 N ANISOU 1908 N ILE B 516 20672 20176 19247 -276 326 1125 N ATOM 1909 CA ILE B 516 -1.424 17.992 30.673 1.00162.82 C ANISOU 1909 CA ILE B 516 21410 20840 19615 -161 499 1080 C ATOM 1910 C ILE B 516 -2.290 17.406 31.785 1.00168.38 C ANISOU 1910 C ILE B 516 22083 21691 20203 -230 552 1164 C ATOM 1911 O ILE B 516 -2.820 16.302 31.639 1.00168.35 O ANISOU 1911 O ILE B 516 21876 21787 20302 -286 506 1243 O ATOM 1912 CB ILE B 516 -2.300 18.603 29.591 1.00160.42 C ANISOU 1912 CB ILE B 516 21026 20599 19328 51 631 1005 C ATOM 1913 N LYS B 517 -2.438 18.128 32.897 1.00169.17 N ANISOU 1913 N LYS B 517 22392 21807 20079 -235 643 1151 N ATOM 1914 CA LYS B 517 -1.812 19.432 33.100 1.00165.50 C ANISOU 1914 CA LYS B 517 22202 21204 19474 -181 678 1063 C ATOM 1915 C LYS B 517 -1.585 19.678 34.590 1.00165.21 C ANISOU 1915 C LYS B 517 22402 21148 19223 -312 684 1096 C ATOM 1916 O LYS B 517 -0.758 19.020 35.221 1.00162.84 O ANISOU 1916 O LYS B 517 22125 20782 18963 -532 530 1180 O ATOM 1917 CB LYS B 517 -2.682 20.535 32.511 1.00161.82 C ANISOU 1917 CB LYS B 517 21784 20783 18918 74 860 961 C TER 1918 LYS B 517 HETATM 1919 C ACT C 19 -4.145 4.297 -15.827 1.00 88.98 C HETATM 1920 O ACT C 19 -5.186 4.982 -15.671 1.00 85.46 O HETATM 1921 OXT ACT C 19 -4.105 3.197 -15.223 1.00 81.38 O HETATM 1922 ZN ZN A1514 -8.231 17.076 -22.340 1.00 51.53 ZN ANISOU 1922 ZN ZN A1514 6847 6294 6439 -1350 514 -714 ZN HETATM 1923 ZN ZN A1515 -15.545 24.384 -10.859 1.00 33.78 ZN ANISOU 1923 ZN ZN A1515 4041 3859 4938 -458 48 -236 ZN HETATM 1924 C ACT A 1 -8.914 15.504 -7.129 1.00 77.37 C HETATM 1925 O ACT A 1 -8.352 14.558 -6.499 1.00 78.28 O HETATM 1926 OXT ACT A 1 -8.163 16.379 -7.619 1.00 72.25 O HETATM 1927 C ACT A 3 -14.103 26.840 -17.411 1.00 79.16 C HETATM 1928 O ACT A 3 -15.305 26.685 -17.763 1.00 91.57 O HETATM 1929 OXT ACT A 3 -13.868 27.205 -16.217 1.00 40.51 O HETATM 1930 ZN ZN B1512 -14.905 15.928 7.535 1.00 49.60 ZN ANISOU 1930 ZN ZN B1512 4842 7155 6848 107 451 1792 ZN HETATM 1931 ZN ZN B1513 -9.591 24.878 -3.901 1.00 31.42 ZN ANISOU 1931 ZN ZN B1513 3142 4076 4722 -414 125 651 ZN HETATM 1932 O HOH C 20 -5.845 10.688 0.066 1.00 45.57 O HETATM 1933 O HOH C 22 -15.371 5.022 -23.248 1.00 64.94 O HETATM 1934 O HOH C 37 -10.116 13.961 -4.434 1.00 64.01 O HETATM 1935 O HOH C 39 -14.812 -3.085 13.840 1.00 63.87 O HETATM 1936 O HOH C 43 -3.791 9.495 -0.864 1.00 53.10 O HETATM 1937 O HOH C 50 -1.725 7.957 0.342 1.00 56.56 O HETATM 1938 O HOH C 58 -0.013 -0.606 -13.803 1.00 69.90 O HETATM 1939 O HOH C 67 -11.888 -6.105 15.417 1.00 52.00 O HETATM 1940 O HOH C 70 -13.902 2.949 13.665 1.00 63.68 O HETATM 1941 O HOH C 80 -6.686 -3.298 10.291 1.00 62.67 O HETATM 1942 O HOH C 87 -10.672 -3.183 7.317 1.00 54.25 O HETATM 1943 O HOH C 89 -13.315 6.127 0.414 1.00 64.67 O HETATM 1944 O HOH C 92 -12.934 -4.037 6.273 1.00 66.35 O HETATM 1945 O HOH C 99 -3.584 7.659 -3.245 1.00 76.57 O HETATM 1946 O HOH C 100 -18.314 4.891 9.506 1.00 74.99 O HETATM 1947 O HOH C 103 -5.957 10.390 -34.140 1.00 69.53 O HETATM 1948 O HOH C 105 -14.580 -5.518 15.314 1.00 63.07 O HETATM 1949 O HOH C 111 -16.634 10.392 6.977 1.00 79.62 O HETATM 1950 O HOH C 114 -15.748 -5.327 17.543 1.00 78.33 O HETATM 1951 O HOH D 19 -11.216 10.716 -18.084 1.00 40.26 O HETATM 1952 O HOH D 20 -7.001 13.569 18.843 1.00 57.33 O HETATM 1953 O HOH D 21 -5.574 12.136 -21.992 1.00 58.24 O HETATM 1954 O HOH D 27 -15.941 10.161 -15.366 1.00 44.36 O HETATM 1955 O HOH D 31 -4.842 3.004 4.992 1.00 62.56 O HETATM 1956 O HOH D 36 -6.034 4.121 -28.421 1.00 65.65 O HETATM 1957 O HOH D 38 -15.565 -2.051 -28.831 1.00 63.43 O HETATM 1958 O HOH D 47 -12.329 -3.150 -25.294 1.00 65.29 O HETATM 1959 O HOH D 48 -8.661 -2.490 -22.259 1.00 57.55 O HETATM 1960 O HOH D 53 -5.744 -0.258 -19.653 1.00 62.33 O HETATM 1961 O HOH D 54 -9.182 13.291 22.971 1.00 69.78 O HETATM 1962 O HOH D 59 -5.125 5.848 8.375 1.00 61.55 O HETATM 1963 O HOH D 61 -5.793 12.727 -13.553 1.00 69.32 O HETATM 1964 O HOH D 81 -2.890 -1.202 4.267 1.00 73.31 O HETATM 1965 O HOH D 82 -5.156 3.251 -0.129 1.00 71.83 O HETATM 1966 O HOH D 84 -13.154 13.713 -9.777 1.00 70.90 O HETATM 1967 O HOH D 85 -17.609 8.339 -14.558 1.00 70.86 O HETATM 1968 O HOH D 90 -15.861 1.886 0.360 1.00 78.28 O HETATM 1969 O HOH D 94 -11.004 -5.639 -1.601 1.00 61.14 O HETATM 1970 O HOH D 97 -14.346 15.337 -7.644 1.00 64.98 O HETATM 1971 O HOH D 101 -2.549 2.468 16.438 1.00 68.84 O HETATM 1972 O HOH D 104 1.072 10.077 15.168 1.00 78.23 O HETATM 1973 O HOH A 2 -14.773 22.418 -7.816 1.00 31.40 O HETATM 1974 O HOH A 8 -21.583 23.826 -10.392 1.00 37.43 O HETATM 1975 O HOH A 12 -13.529 29.906 -7.151 1.00 40.98 O HETATM 1976 O HOH A 15 -18.231 33.085 -12.100 1.00 39.50 O HETATM 1977 O HOH A 16 -15.519 7.480 -25.440 1.00 51.00 O HETATM 1978 O HOH A 19 -12.696 15.250 -14.262 1.00 43.39 O HETATM 1979 O HOH A 24 -9.243 26.546 -17.882 1.00 48.39 O HETATM 1980 O HOH A 26 -17.167 30.422 -16.204 1.00 56.72 O HETATM 1981 O HOH A 28 -21.348 21.746 -15.662 1.00 52.09 O HETATM 1982 O HOH A 33 -11.950 25.772 -25.409 1.00 63.04 O HETATM 1983 O HOH A 34 -23.798 16.011 -26.832 1.00 69.30 O HETATM 1984 O HOH A 35 -13.683 9.624 -17.111 1.00 46.92 O HETATM 1985 O HOH A 41 -12.000 30.617 -9.628 1.00 62.74 O HETATM 1986 O HOH A 42 -17.434 33.101 -14.858 1.00 52.81 O HETATM 1987 O HOH A 46 -6.171 24.538 -19.932 1.00 48.43 O HETATM 1988 O HOH A 56 -2.553 27.933 -15.310 1.00 68.92 O HETATM 1989 O HOH A 57 -6.426 24.269 -24.524 1.00 67.70 O HETATM 1990 O HOH A 62 -6.164 27.231 -18.640 1.00 65.35 O HETATM 1991 O HOH A 63 -22.664 22.571 -17.972 1.00 72.15 O HETATM 1992 O HOH A 66 -11.396 27.737 -18.376 1.00 58.60 O HETATM 1993 O HOH A 74 -22.795 19.919 -14.676 1.00 68.56 O HETATM 1994 O HOH A 76 -23.152 14.025 -9.514 1.00 63.02 O HETATM 1995 O HOH A 77 -4.699 10.974 -24.937 1.00 61.87 O HETATM 1996 O HOH A 78 -7.789 25.888 -22.890 1.00 71.80 O HETATM 1997 O HOH A 83 -23.670 16.852 -14.941 1.00 73.05 O HETATM 1998 O HOH A 88 -14.702 30.212 -16.952 1.00 67.19 O HETATM 1999 O HOH A 91 -2.462 12.423 -23.589 1.00 74.70 O HETATM 2000 O HOH A 106 -3.075 25.754 -16.739 1.00 69.99 O HETATM 2001 O HOH A 108 -17.422 19.412 -9.929 1.00 38.06 O HETATM 2002 O HOH A 110 -17.679 11.810 -16.567 1.00 59.19 O HETATM 2003 O HOH A 115 -5.239 23.071 -29.799 1.00 80.61 O HETATM 2004 O HOH A 526 -14.405 28.269 -9.783 1.00 35.59 O HETATM 2005 O HOH B 1 -9.907 22.875 -7.130 1.00 31.42 O HETATM 2006 O HOH B 4 -12.447 23.864 -7.309 1.00 35.60 O HETATM 2007 O HOH B 5 -12.216 28.494 -5.056 1.00 32.56 O HETATM 2008 O HOH B 6 -3.245 23.053 0.690 1.00 31.53 O HETATM 2009 O HOH B 7 -1.657 21.625 -0.964 1.00 40.77 O HETATM 2010 O HOH B 9 -10.828 10.402 3.058 1.00 44.64 O HETATM 2011 O HOH B 13 -10.292 29.687 -11.197 1.00 48.65 O HETATM 2012 O HOH B 14 -4.573 12.816 1.516 1.00 43.40 O HETATM 2013 O HOH B 17 -12.394 27.031 1.901 1.00 57.51 O HETATM 2014 O HOH B 21 -10.167 15.367 -0.626 1.00 44.59 O HETATM 2015 O HOH B 23 -8.320 9.891 2.040 1.00 45.95 O HETATM 2016 O HOH B 25 -5.695 7.942 10.033 1.00 49.51 O HETATM 2017 O HOH B 29 -14.346 7.554 12.036 1.00 57.59 O HETATM 2018 O HOH B 30 -12.182 36.601 -5.246 1.00 66.77 O HETATM 2019 O HOH B 32 -11.887 27.623 4.556 1.00 66.13 O HETATM 2020 O HOH B 40 -6.632 20.403 -5.072 1.00 44.59 O HETATM 2021 O HOH B 44 1.262 18.706 -8.344 1.00 55.35 O HETATM 2022 O HOH B 45 -21.256 19.285 5.200 1.00 64.73 O HETATM 2023 O HOH B 49 -6.082 26.065 -1.192 1.00 57.16 O HETATM 2024 O HOH B 51 -3.065 4.957 3.458 1.00 58.27 O HETATM 2025 O HOH B 52 -10.735 24.965 8.956 1.00 48.09 O HETATM 2026 O HOH B 55 -23.684 19.975 15.382 1.00 68.13 O HETATM 2027 O HOH B 60 -9.000 30.929 1.655 1.00 58.05 O HETATM 2028 O HOH B 64 -15.291 26.585 8.683 1.00 69.69 O HETATM 2029 O HOH B 65 -0.724 12.546 -0.301 1.00 68.20 O HETATM 2030 O HOH B 68 -0.450 22.763 -2.631 1.00 48.67 O HETATM 2031 O HOH B 69 0.644 14.230 -3.124 1.00 68.30 O HETATM 2032 O HOH B 71 -4.187 18.622 -7.317 1.00 74.35 O HETATM 2033 O HOH B 72 -6.563 30.737 3.381 1.00 69.42 O HETATM 2034 O HOH B 73 -2.602 11.801 -1.894 1.00 67.76 O HETATM 2035 O HOH B 75 -12.718 24.072 10.393 1.00 70.13 O HETATM 2036 O HOH B 79 -2.173 6.328 19.765 1.00 65.20 O HETATM 2037 O HOH B 86 -17.575 10.075 10.475 1.00 65.78 O HETATM 2038 O HOH B 93 -13.570 28.163 7.366 1.00 73.87 O HETATM 2039 O HOH B 95 -15.991 29.238 0.378 1.00 68.26 O HETATM 2040 O HOH B 96 -15.427 25.305 3.332 1.00 43.60 O HETATM 2041 O HOH B 98 -17.481 23.830 6.268 1.00 72.73 O HETATM 2042 O HOH B 102 -11.475 33.966 -0.087 1.00 64.28 O HETATM 2043 O HOH B 107 -15.193 36.921 -9.436 1.00 76.57 O HETATM 2044 O HOH B 109 2.090 6.063 10.709 1.00 58.85 O HETATM 2045 O HOH B 112 -21.655 13.038 15.866 1.00 76.64 O HETATM 2046 O HOH B 113 -3.602 19.601 19.397 1.00 61.49 O CONECT 760 1922 CONECT 781 1922 CONECT 879 1922 CONECT 895 1922 CONECT 1031 1923 CONECT 1073 1923 CONECT 1159 1923 CONECT 1177 1923 CONECT 1331 1930 CONECT 1352 1930 CONECT 1450 1930 CONECT 1466 1930 CONECT 1602 1931 CONECT 1644 1931 CONECT 1730 1931 CONECT 1748 1931 CONECT 1919 1920 1921 CONECT 1920 1919 CONECT 1921 1919 CONECT 1922 760 781 879 895 CONECT 1923 1031 1073 1159 1177 CONECT 1924 1925 1926 CONECT 1925 1924 CONECT 1926 1924 CONECT 1927 1928 1929 CONECT 1928 1927 CONECT 1929 1927 CONECT 1930 1331 1352 1450 1466 CONECT 1931 1602 1644 1730 1748 MASTER 455 0 7 5 4 0 7 6 2042 4 29 18 END
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Related entries of code: 3g6p
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PDB Code
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Ligand Name
2kx5
RCSB PDB
PDBbind
18-mer
6blw
RCSB PDB
PDBbind
18-mer
6a2i
RCSB PDB
PDBbind
18-mer
Entry Information
PDB ID
3g6p
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Glucocorticoid receptor DNA binding domain
Ligand Name
18-mer
EC.Number
E.C.-.-.-.-
Resolution
1.99(Å)
Affinity (Kd/Ki/IC50)
Kd=0.44uM
Release Year
2009
Protein/NA Sequence
Check fasta file
Primary Reference
(2009) Science Vol. 324: pp. 407-410
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P06536
Entrez Gene ID
NCBI Entrez Gene ID:
24413
ASD
Information of known allosteric effects of PDB entries
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