Browse entries in the PDBbind-CN Database
HEADER DNA BINDING PROTEIN/DNA 11-NOV-17 6BLW TITLE ZINC FINGER DOMAIN OF WT1(+KTS FORM) WITH M342R MUTATION AND 17+1MER TITLE 2 OLIGONUCLEOTIDE WITH TRIPLET GGT COMPND MOL_ID: 1; COMPND 2 MOLECULE: WILMS TUMOR PROTEIN; COMPND 3 CHAIN: A; COMPND 4 SYNONYM: WT33; COMPND 5 ENGINEERED: YES; COMPND 6 MUTATION: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'- COMPND 9 D(P*GP*CP*GP*AP*AP*AP*TP*GP*GP*GP*AP*GP*GP*GP*TP*T)-3'); COMPND 10 CHAIN: B; COMPND 11 ENGINEERED: YES; COMPND 12 MOL_ID: 3; COMPND 13 MOLECULE: DNA (5'- COMPND 14 D(*TP*AP*AP*CP*CP*CP*TP*CP*CP*CP*AP*TP*TP*TP*CP*GP*C)-3'); COMPND 15 CHAIN: C; COMPND 16 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: WT1; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG'; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 866768; SOURCE 8 MOL_ID: 2; SOURCE 9 SYNTHETIC: YES; SOURCE 10 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 11 ORGANISM_TAXID: 9606; SOURCE 12 MOL_ID: 3; SOURCE 13 SYNTHETIC: YES; SOURCE 14 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 15 ORGANISM_TAXID: 9606 KEYWDS PROTEIN-DNA COMPLEX WILMS TUMOR SUPPRESSOR PROTEIN ZINC-FINGERS, DNA KEYWDS 2 BINDING PROTEIN-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR J.R.HORTON,X.CHENG REVDAT 3 16-MAY-18 6BLW 1 JRNL REVDAT 2 17-JAN-18 6BLW 1 JRNL REVDAT 1 03-JAN-18 6BLW 0 JRNL AUTH D.WANG,J.R.HORTON,Y.ZHENG,R.M.BLUMENTHAL,X.ZHANG,X.CHENG JRNL TITL ROLE FOR FIRST ZINC FINGER OF WT1 IN DNA SEQUENCE JRNL TITL 2 SPECIFICITY: DENYS-DRASH SYNDROME-ASSOCIATED WT1 MUTANT IN JRNL TITL 3 ZF1 ENHANCES AFFINITY FOR A SUBSET OF WT1 BINDING SITES. JRNL REF NUCLEIC ACIDS RES. V. 46 3864 2018 JRNL REFN ESSN 1362-4962 JRNL PMID 29294058 JRNL DOI 10.1093/NAR/GKX1274 REMARK 2 REMARK 2 RESOLUTION. 1.84 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX 1.12_2829 REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.84 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 29.69 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.360 REMARK 3 COMPLETENESS FOR RANGE (%) : 94.3 REMARK 3 NUMBER OF REFLECTIONS : 21595 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.223 REMARK 3 R VALUE (WORKING SET) : 0.222 REMARK 3 FREE R VALUE : 0.247 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.010 REMARK 3 FREE R VALUE TEST SET COUNT : 1079 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 29.6949 - 4.4190 0.99 2893 154 0.1803 0.2076 REMARK 3 2 4.4190 - 3.5093 1.00 2923 150 0.1787 0.2152 REMARK 3 3 3.5093 - 3.0662 1.00 2901 156 0.1983 0.2054 REMARK 3 4 3.0662 - 2.7861 1.00 2926 147 0.2756 0.2910 REMARK 3 5 2.7861 - 2.5865 1.00 2884 157 0.2688 0.2886 REMARK 3 6 2.5865 - 2.4341 1.00 2932 153 0.2597 0.3202 REMARK 3 7 2.4341 - 2.3123 1.00 2902 151 0.2829 0.3350 REMARK 3 8 2.3123 - 2.2116 1.00 2907 150 0.2838 0.2353 REMARK 3 9 2.2116 - 2.1265 1.00 2896 152 0.2905 0.3179 REMARK 3 10 2.1265 - 2.0532 0.99 2874 159 0.3091 0.3081 REMARK 3 11 2.0532 - 1.9890 0.95 2761 148 0.3366 0.3245 REMARK 3 12 1.9890 - 1.9321 0.88 2561 132 0.3395 0.3927 REMARK 3 13 1.9321 - 1.8813 0.81 2357 125 0.3640 0.4081 REMARK 3 14 1.8813 - 1.8354 0.59 1683 93 0.3635 0.4110 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.260 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 32.310 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.005 1672 REMARK 3 ANGLE : 0.523 2358 REMARK 3 CHIRALITY : 0.030 248 REMARK 3 PLANARITY : 0.003 189 REMARK 3 DIHEDRAL : 19.261 863 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 15 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 317 THROUGH 336 ) REMARK 3 ORIGIN FOR THE GROUP (A): -12.5749 -10.1096 30.4837 REMARK 3 T TENSOR REMARK 3 T11: 0.4418 T22: 0.7645 REMARK 3 T33: 0.4348 T12: -0.1685 REMARK 3 T13: 0.0304 T23: 0.1095 REMARK 3 L TENSOR REMARK 3 L11: 0.3512 L22: 1.0192 REMARK 3 L33: 0.4332 L12: -0.4737 REMARK 3 L13: 0.3354 L23: -0.2368 REMARK 3 S TENSOR REMARK 3 S11: 0.3158 S12: -0.3579 S13: -0.1978 REMARK 3 S21: 0.3615 S22: -0.4444 S23: -0.3704 REMARK 3 S31: 0.2019 S32: -0.6836 S33: 0.0007 REMARK 3 TLS GROUP : 2 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 337 THROUGH 348 ) REMARK 3 ORIGIN FOR THE GROUP (A): -18.6925 -4.4615 24.9237 REMARK 3 T TENSOR REMARK 3 T11: 0.4652 T22: 0.8128 REMARK 3 T33: 0.3112 T12: 0.0972 REMARK 3 T13: 0.0484 T23: -0.1272 REMARK 3 L TENSOR REMARK 3 L11: 2.2225 L22: 7.5165 REMARK 3 L33: 1.5884 L12: 1.9436 REMARK 3 L13: 0.0053 L23: -3.0340 REMARK 3 S TENSOR REMARK 3 S11: 0.1183 S12: 0.2342 S13: -0.3819 REMARK 3 S21: 0.2033 S22: -0.4847 S23: -0.3867 REMARK 3 S31: -1.3161 S32: -1.1785 S33: -0.6139 REMARK 3 TLS GROUP : 3 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 349 THROUGH 353 ) REMARK 3 ORIGIN FOR THE GROUP (A): -27.1232 -1.6488 16.8791 REMARK 3 T TENSOR REMARK 3 T11: 0.4803 T22: 1.1658 REMARK 3 T33: 0.5251 T12: 0.1844 REMARK 3 T13: 0.1332 T23: 0.0083 REMARK 3 L TENSOR REMARK 3 L11: 0.1731 L22: 1.3232 REMARK 3 L33: 0.6032 L12: 0.4154 REMARK 3 L13: -0.1160 L23: 0.0810 REMARK 3 S TENSOR REMARK 3 S11: -0.3030 S12: -1.0220 S13: -0.2720 REMARK 3 S21: 0.1689 S22: 0.0417 S23: 0.2260 REMARK 3 S31: 0.1189 S32: -0.8924 S33: -0.1039 REMARK 3 TLS GROUP : 4 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 354 THROUGH 366 ) REMARK 3 ORIGIN FOR THE GROUP (A): -29.1073 -3.9824 8.5063 REMARK 3 T TENSOR REMARK 3 T11: 0.3589 T22: 0.6984 REMARK 3 T33: 0.4577 T12: -0.0127 REMARK 3 T13: 0.0536 T23: 0.0640 REMARK 3 L TENSOR REMARK 3 L11: 0.3025 L22: 0.1632 REMARK 3 L33: 0.1644 L12: 0.2443 REMARK 3 L13: -0.0520 L23: -0.0643 REMARK 3 S TENSOR REMARK 3 S11: 0.1772 S12: -0.5181 S13: 0.1406 REMARK 3 S21: 0.0445 S22: 0.0489 S23: 0.4456 REMARK 3 S31: 0.5360 S32: -0.8766 S33: 0.0003 REMARK 3 TLS GROUP : 5 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 367 THROUGH 383 ) REMARK 3 ORIGIN FOR THE GROUP (A): -19.2531 -5.2705 3.2448 REMARK 3 T TENSOR REMARK 3 T11: 0.3429 T22: 0.4240 REMARK 3 T33: 0.3494 T12: -0.0324 REMARK 3 T13: 0.0178 T23: -0.0112 REMARK 3 L TENSOR REMARK 3 L11: 0.5316 L22: 0.5572 REMARK 3 L33: 0.0566 L12: 0.0488 REMARK 3 L13: -0.1748 L23: -0.0460 REMARK 3 S TENSOR REMARK 3 S11: -0.1702 S12: -0.2710 S13: -0.1423 REMARK 3 S21: -0.0511 S22: 0.0614 S23: -0.0258 REMARK 3 S31: 0.0762 S32: -0.2378 S33: 0.0000 REMARK 3 TLS GROUP : 6 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 384 THROUGH 394 ) REMARK 3 ORIGIN FOR THE GROUP (A): -9.8416 -13.4687 -5.4663 REMARK 3 T TENSOR REMARK 3 T11: 0.4197 T22: 0.4766 REMARK 3 T33: 0.4480 T12: 0.0213 REMARK 3 T13: 0.0663 T23: -0.0230 REMARK 3 L TENSOR REMARK 3 L11: 0.1432 L22: 0.3842 REMARK 3 L33: 0.1716 L12: -0.1114 REMARK 3 L13: 0.0435 L23: 0.1862 REMARK 3 S TENSOR REMARK 3 S11: 0.1175 S12: 0.5514 S13: -0.1424 REMARK 3 S21: -0.2302 S22: -0.0689 S23: -0.3728 REMARK 3 S31: 0.1452 S32: 0.1080 S33: 0.0000 REMARK 3 TLS GROUP : 7 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 395 THROUGH 407 ) REMARK 3 ORIGIN FOR THE GROUP (A): -8.3631 -19.9254 -0.1867 REMARK 3 T TENSOR REMARK 3 T11: 0.3977 T22: 0.3519 REMARK 3 T33: 0.4948 T12: 0.0198 REMARK 3 T13: -0.0082 T23: -0.0750 REMARK 3 L TENSOR REMARK 3 L11: 0.0596 L22: 0.0821 REMARK 3 L33: 0.1776 L12: 0.0121 REMARK 3 L13: -0.0170 L23: 0.1889 REMARK 3 S TENSOR REMARK 3 S11: 0.1496 S12: -0.2951 S13: -0.5312 REMARK 3 S21: -0.0466 S22: -0.3813 S23: 0.8231 REMARK 3 S31: 0.3071 S32: 0.2850 S33: 0.0002 REMARK 3 TLS GROUP : 8 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 408 THROUGH 422 ) REMARK 3 ORIGIN FOR THE GROUP (A): -8.4761 -22.8347 -14.7810 REMARK 3 T TENSOR REMARK 3 T11: 1.2069 T22: 1.1543 REMARK 3 T33: 0.7482 T12: 0.2433 REMARK 3 T13: 0.0908 T23: -0.3822 REMARK 3 L TENSOR REMARK 3 L11: 4.2357 L22: 0.2989 REMARK 3 L33: 0.3267 L12: 0.7929 REMARK 3 L13: -0.6018 L23: -0.3089 REMARK 3 S TENSOR REMARK 3 S11: -0.2850 S12: 1.2447 S13: 0.3837 REMARK 3 S21: 1.2343 S22: 0.5972 S23: -1.0860 REMARK 3 S31: 0.9259 S32: -1.0902 S33: 0.0400 REMARK 3 TLS GROUP : 9 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 431 THROUGH 436 ) REMARK 3 ORIGIN FOR THE GROUP (A): -10.2191 -14.8580 -16.8258 REMARK 3 T TENSOR REMARK 3 T11: 0.9696 T22: 1.0494 REMARK 3 T33: 0.9292 T12: 0.1330 REMARK 3 T13: 0.1584 T23: -0.1867 REMARK 3 L TENSOR REMARK 3 L11: 0.3362 L22: 0.0486 REMARK 3 L33: 0.2624 L12: -0.0005 REMARK 3 L13: 0.2855 L23: -0.0292 REMARK 3 S TENSOR REMARK 3 S11: -1.5429 S12: 0.7255 S13: 0.8376 REMARK 3 S21: -0.1133 S22: -0.1052 S23: 0.1163 REMARK 3 S31: -0.7351 S32: 0.6737 S33: -0.0251 REMARK 3 TLS GROUP : 10 REMARK 3 SELECTION: CHAIN 'B' AND (RESID 2 THROUGH 6 ) REMARK 3 ORIGIN FOR THE GROUP (A): -21.5821 -31.7985 -2.4905 REMARK 3 T TENSOR REMARK 3 T11: 0.8194 T22: 0.4873 REMARK 3 T33: 0.4877 T12: -0.1931 REMARK 3 T13: 0.1312 T23: -0.2513 REMARK 3 L TENSOR REMARK 3 L11: 0.2536 L22: 1.6616 REMARK 3 L33: 0.7174 L12: 0.1411 REMARK 3 L13: -0.1589 L23: -1.0493 REMARK 3 S TENSOR REMARK 3 S11: 0.0075 S12: -0.8885 S13: -0.1005 REMARK 3 S21: 0.2914 S22: -0.8197 S23: -0.0280 REMARK 3 S31: 0.1415 S32: -0.4123 S33: -0.6360 REMARK 3 TLS GROUP : 11 REMARK 3 SELECTION: CHAIN 'B' AND (RESID 7 THROUGH 17 ) REMARK 3 ORIGIN FOR THE GROUP (A): -13.9261 -10.7879 12.3153 REMARK 3 T TENSOR REMARK 3 T11: 0.4551 T22: 0.4170 REMARK 3 T33: 0.4833 T12: -0.0516 REMARK 3 T13: -0.0014 T23: 0.0045 REMARK 3 L TENSOR REMARK 3 L11: 1.4437 L22: 1.1667 REMARK 3 L33: 1.0382 L12: -0.5612 REMARK 3 L13: -0.4039 L23: -0.9091 REMARK 3 S TENSOR REMARK 3 S11: -0.1337 S12: -0.2112 S13: 0.0170 REMARK 3 S21: -0.1410 S22: -0.0253 S23: -0.2449 REMARK 3 S31: -0.1464 S32: -0.0822 S33: 0.0001 REMARK 3 TLS GROUP : 12 REMARK 3 SELECTION: CHAIN 'C' AND (RESID 2 THROUGH 6 ) REMARK 3 ORIGIN FOR THE GROUP (A): -12.1481 1.9577 15.5227 REMARK 3 T TENSOR REMARK 3 T11: 0.4530 T22: 0.4583 REMARK 3 T33: 0.4320 T12: 0.0190 REMARK 3 T13: -0.0706 T23: -0.0586 REMARK 3 L TENSOR REMARK 3 L11: 0.1211 L22: 0.4725 REMARK 3 L33: 0.2149 L12: 0.1114 REMARK 3 L13: 0.0051 L23: -0.2970 REMARK 3 S TENSOR REMARK 3 S11: 0.2580 S12: -0.0705 S13: -0.2180 REMARK 3 S21: 0.0358 S22: -0.3146 S23: -0.4852 REMARK 3 S31: -0.4993 S32: -0.8203 S33: -0.0001 REMARK 3 TLS GROUP : 13 REMARK 3 SELECTION: CHAIN 'C' AND (RESID 7 THROUGH 11 ) REMARK 3 ORIGIN FOR THE GROUP (A): -11.5472 -16.3520 11.8290 REMARK 3 T TENSOR REMARK 3 T11: 0.4373 T22: 0.3514 REMARK 3 T33: 0.4906 T12: -0.0228 REMARK 3 T13: -0.0282 T23: 0.0058 REMARK 3 L TENSOR REMARK 3 L11: 0.3555 L22: 0.1010 REMARK 3 L33: 0.0374 L12: -0.1906 REMARK 3 L13: 0.1248 L23: -0.0681 REMARK 3 S TENSOR REMARK 3 S11: 0.3295 S12: -0.2664 S13: -0.3252 REMARK 3 S21: -0.4250 S22: -0.2825 S23: 0.0978 REMARK 3 S31: 0.2390 S32: -0.0124 S33: 0.0001 REMARK 3 TLS GROUP : 14 REMARK 3 SELECTION: CHAIN 'C' AND (RESID 12 THROUGH 16 ) REMARK 3 ORIGIN FOR THE GROUP (A): -24.8553 -22.9753 2.1647 REMARK 3 T TENSOR REMARK 3 T11: 0.5763 T22: 0.5091 REMARK 3 T33: 0.4520 T12: -0.2204 REMARK 3 T13: 0.0267 T23: -0.0995 REMARK 3 L TENSOR REMARK 3 L11: 0.7934 L22: 0.1774 REMARK 3 L33: 0.1019 L12: 0.0607 REMARK 3 L13: -0.1516 L23: -0.0724 REMARK 3 S TENSOR REMARK 3 S11: 0.0857 S12: 0.1709 S13: -0.5277 REMARK 3 S21: 0.0518 S22: -0.1054 S23: 0.1303 REMARK 3 S31: 0.4231 S32: -0.9145 S33: 0.0183 REMARK 3 TLS GROUP : 15 REMARK 3 SELECTION: CHAIN 'C' AND (RESID 17 THROUGH 18 ) REMARK 3 ORIGIN FOR THE GROUP (A): -19.9156 -28.9779 -10.5210 REMARK 3 T TENSOR REMARK 3 T11: 0.7986 T22: 0.4637 REMARK 3 T33: 0.5395 T12: -0.2104 REMARK 3 T13: 0.2095 T23: -0.1697 REMARK 3 L TENSOR REMARK 3 L11: 2.1275 L22: 0.0213 REMARK 3 L33: 0.8660 L12: -0.2066 REMARK 3 L13: 1.3510 L23: -0.1239 REMARK 3 S TENSOR REMARK 3 S11: 1.3395 S12: -0.3994 S13: -0.1318 REMARK 3 S21: -0.8962 S22: -0.6074 S23: -0.2245 REMARK 3 S31: -0.0437 S32: -0.4381 S33: 0.1123 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 6BLW COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 13-NOV-17. REMARK 100 THE DEPOSITION ID IS D_1000229846. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 18-APR-17 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 9.5 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : APS REMARK 200 BEAMLINE : 22-ID REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.00000 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : RAYONIX MX300-HS REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 21595 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.835 REMARK 200 RESOLUTION RANGE LOW (A) : 29.700 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 96.5 REMARK 200 DATA REDUNDANCY : 32.70 REMARK 200 R MERGE (I) : 0.13200 REMARK 200 R SYM (I) : NULL REMARK 200
FOR THE DATA SET : 25.7000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.84 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.92 REMARK 200 COMPLETENESS FOR SHELL (%) : 80.5 REMARK 200 DATA REDUNDANCY IN SHELL : 14.00 REMARK 200 R MERGE FOR SHELL (I) : 0.93700 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200
FOR SHELL : 2.400 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHENIX REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 48.95 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.41 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 30% PEG 300 0.1M CHES:NAOH, PH 9.5, REMARK 280 VAPOR DIFFUSION, SITTING DROP, TEMPERATURE 289K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 2 2 21 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -X,Y,-Z+1/2 REMARK 290 4555 X,-Y,-Z REMARK 290 5555 X+1/2,Y+1/2,Z REMARK 290 6555 -X+1/2,-Y+1/2,Z+1/2 REMARK 290 7555 -X+1/2,Y+1/2,-Z+1/2 REMARK 290 8555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 41.67000 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 41.67000 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 5 1.000000 0.000000 0.000000 31.77600 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 47.78600 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 6 -1.000000 0.000000 0.000000 31.77600 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 47.78600 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 41.67000 REMARK 290 SMTRY1 7 -1.000000 0.000000 0.000000 31.77600 REMARK 290 SMTRY2 7 0.000000 1.000000 0.000000 47.78600 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 41.67000 REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 31.77600 REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 47.78600 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 5640 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 11390 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -22.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 THR A 409 REMARK 465 SER A 410 REMARK 465 GLU A 411 REMARK 465 LYS A 412 REMARK 465 PRO A 413 REMARK 465 PHE A 414 REMARK 465 LYS A 423 REMARK 465 LYS A 424 REMARK 465 PHE A 425 REMARK 465 ALA A 426 REMARK 465 ARG A 427 REMARK 465 SER A 428 REMARK 465 ASP A 429 REMARK 465 GLU A 430 REMARK 465 ARG A 440 REMARK 465 DA B 1 REMARK 465 DA B 18 REMARK 465 DT C 1 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 HIS A 317 CG ND1 CD2 CE1 NE2 REMARK 470 MET A 318 CG SD CE REMARK 470 LYS A 320 CG CD CE NZ REMARK 470 MET A 324 CG SD CE REMARK 470 ASN A 331 CG OD1 ND2 REMARK 470 GLU A 350 CG CD OE1 OE2 REMARK 470 PHE A 357 CD1 CD2 CE1 CE2 CZ REMARK 470 LYS A 358 CG CD CE NZ REMARK 470 GLU A 361 CG CD OE1 OE2 REMARK 470 LYS A 386 CG CD CE NZ REMARK 470 LYS A 399 CG CD CE NZ REMARK 470 LYS A 408 CG CD CE NZ REMARK 470 GLN A 422 CG CD OE1 NE2 REMARK 470 LEU A 431 CG CD1 CD2 REMARK 470 VAL A 432 CG1 CG2 REMARK 470 ARG A 433 CG CD NE CZ NH1 NH2 REMARK 470 ASN A 436 CG OD1 ND2 REMARK 470 MET A 437 CG SD CE REMARK 470 GLN A 439 CG CD OE1 NE2 REMARK 470 DT C 2 P OP1 OP2 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 CYS A 360 -70.19 -117.67 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 503 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 325 SG REMARK 620 2 CYS A 330 SG 116.2 REMARK 620 3 HIS A 343 NE2 111.9 109.7 REMARK 620 4 HIS A 347 NE2 107.3 110.6 99.8 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 501 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 355 SG REMARK 620 2 CYS A 360 SG 112.6 REMARK 620 3 HIS A 373 NE2 109.0 105.8 REMARK 620 4 HIS A 377 NE2 110.7 116.3 101.5 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 502 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 385 SG REMARK 620 2 CYS A 388 SG 114.0 REMARK 620 3 HIS A 401 NE2 113.6 95.9 REMARK 620 4 HIS A 405 NE2 111.1 114.1 107.2 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 504 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 416 SG REMARK 620 2 CYS A 421 SG 107.2 REMARK 620 3 HIS A 434 NE2 48.7 111.5 REMARK 620 4 HIS A 438 NE2 113.1 133.8 81.0 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 501 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 502 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 503 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 504 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC5 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue EDO A 505 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC6 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue EDO A 506 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC7 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue EDO A 507 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC8 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue EDO A 508 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC9 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue GOL A 509 DBREF 6BLW A 319 440 UNP P19544 WT1_HUMAN 375 496 DBREF 6BLW B 1 18 PDB 6BLW 6BLW 1 18 DBREF 6BLW C 1 18 PDB 6BLW 6BLW 1 18 SEQADV 6BLW HIS A 317 UNP P19544 EXPRESSION TAG SEQADV 6BLW MET A 318 UNP P19544 EXPRESSION TAG SEQADV 6BLW ARG A 342 UNP P19544 MET 398 ENGINEERED MUTATION SEQRES 1 A 124 HIS MET GLU LYS ARG PRO PHE MET CYS ALA TYR PRO GLY SEQRES 2 A 124 CYS ASN LYS ARG TYR PHE LYS LEU SER HIS LEU GLN ARG SEQRES 3 A 124 HIS SER ARG LYS HIS THR GLY GLU LYS PRO TYR GLN CYS SEQRES 4 A 124 ASP PHE LYS ASP CYS GLU ARG ARG PHE SER ARG SER ASP SEQRES 5 A 124 GLN LEU LYS ARG HIS GLN ARG ARG HIS THR GLY VAL LYS SEQRES 6 A 124 PRO PHE GLN CYS LYS THR CYS GLN ARG LYS PHE SER ARG SEQRES 7 A 124 SER ASP HIS LEU LYS THR HIS THR ARG THR HIS THR GLY SEQRES 8 A 124 LYS THR SER GLU LYS PRO PHE SER CYS ARG TRP PRO SER SEQRES 9 A 124 CYS GLN LYS LYS PHE ALA ARG SER ASP GLU LEU VAL ARG SEQRES 10 A 124 HIS HIS ASN MET HIS GLN ARG SEQRES 1 B 18 DA DG DC DG DA DA DA DT DG DG DG DA DG SEQRES 2 B 18 DG DG DT DT DA SEQRES 1 C 18 DT DT DA DA DC DC DC DT DC DC DC DA DT SEQRES 2 C 18 DT DT DC DG DC HET ZN A 501 1 HET ZN A 502 1 HET ZN A 503 1 HET ZN A 504 1 HET EDO A 505 4 HET EDO A 506 4 HET EDO A 507 4 HET EDO A 508 4 HET GOL A 509 6 HETNAM ZN ZINC ION HETNAM EDO 1,2-ETHANEDIOL HETNAM GOL GLYCEROL HETSYN EDO ETHYLENE GLYCOL HETSYN GOL GLYCERIN; PROPANE-1,2,3-TRIOL FORMUL 4 ZN 4(ZN 2+) FORMUL 8 EDO 4(C2 H6 O2) FORMUL 12 GOL C3 H8 O3 FORMUL 13 HOH *71(H2 O) HELIX 1 AA1 LYS A 336 GLY A 349 1 14 HELIX 2 AA2 ARG A 366 GLY A 379 1 14 HELIX 3 AA3 ARG A 394 THR A 402 1 9 HELIX 4 AA4 THR A 402 LYS A 408 1 7 HELIX 5 AA5 VAL A 432 HIS A 438 1 7 SHEET 1 AA1 2 PHE A 323 MET A 324 0 SHEET 2 AA1 2 ARG A 333 TYR A 334 -1 O TYR A 334 N PHE A 323 SHEET 1 AA2 2 TYR A 353 GLN A 354 0 SHEET 2 AA2 2 ARG A 363 PHE A 364 -1 O PHE A 364 N TYR A 353 SHEET 1 AA3 2 PHE A 383 GLN A 384 0 SHEET 2 AA3 2 LYS A 391 PHE A 392 -1 O PHE A 392 N PHE A 383 LINK SG CYS A 325 ZN ZN A 503 1555 1555 2.29 LINK SG CYS A 330 ZN ZN A 503 1555 1555 2.28 LINK NE2 HIS A 343 ZN ZN A 503 1555 1555 2.03 LINK NE2 HIS A 347 ZN ZN A 503 1555 1555 2.01 LINK SG CYS A 355 ZN ZN A 501 1555 1555 2.26 LINK SG CYS A 360 ZN ZN A 501 1555 1555 2.26 LINK NE2 HIS A 373 ZN ZN A 501 1555 1555 2.02 LINK NE2 HIS A 377 ZN ZN A 501 1555 1555 2.03 LINK SG CYS A 385 ZN ZN A 502 1555 1555 2.34 LINK SG CYS A 388 ZN ZN A 502 1555 1555 2.27 LINK NE2 HIS A 401 ZN ZN A 502 1555 1555 2.03 LINK NE2 HIS A 405 ZN ZN A 502 1555 1555 2.03 LINK SG CYS A 416 NE2 HIS A 434 1555 1555 1.84 LINK SG CYS A 416 ZN ZN A 504 1555 1555 2.38 LINK SG CYS A 421 ZN ZN A 504 1555 1555 2.22 LINK NE2 HIS A 434 ZN ZN A 504 1555 1555 2.01 LINK NE2 HIS A 438 ZN ZN A 504 1555 1555 2.03 SITE 1 AC1 4 CYS A 355 CYS A 360 HIS A 373 HIS A 377 SITE 1 AC2 4 CYS A 385 CYS A 388 HIS A 401 HIS A 405 SITE 1 AC3 4 CYS A 325 CYS A 330 HIS A 343 HIS A 347 SITE 1 AC4 4 CYS A 416 CYS A 421 HIS A 434 HIS A 438 SITE 1 AC5 5 LYS A 381 SER A 393 HIS A 397 DT B 8 SITE 2 AC5 5 DG B 9 SITE 1 AC6 7 ARG A 372 SER A 393 ARG A 394 HIS A 397 SITE 2 AC6 7 DT B 8 DG B 9 HOH B 103 SITE 1 AC7 7 ARG A 366 ASP A 368 ARG A 372 DA B 12 SITE 2 AC7 7 DG B 13 HOH B 108 DC C 7 SITE 1 AC8 5 LYS A 371 LYS A 381 DC C 5 DC C 6 SITE 2 AC8 5 HOH C 108 SITE 1 AC9 2 LEU A 431 VAL A 432 CRYST1 63.552 95.572 83.340 90.00 90.00 90.00 C 2 2 21 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.015735 0.000000 0.000000 0.00000 SCALE2 0.000000 0.010463 0.000000 0.00000 SCALE3 0.000000 0.000000 0.011999 0.00000 ATOM 1 N HIS A 317 2.318 -15.507 23.977 1.00 94.20 N ANISOU 1 N HIS A 317 11087 10765 13940 -632 -118 2755 N ATOM 2 CA HIS A 317 0.864 -15.588 24.048 1.00 91.98 C ANISOU 2 CA HIS A 317 10811 10694 13444 -756 -67 2701 C ATOM 3 C HIS A 317 0.388 -15.583 25.497 1.00 92.13 C ANISOU 3 C HIS A 317 10868 10847 13289 -1016 -189 2674 C ATOM 4 O HIS A 317 0.362 -16.622 26.156 1.00 96.36 O ANISOU 4 O HIS A 317 11473 11360 13779 -1225 -295 2732 O ATOM 5 CB HIS A 317 0.366 -16.833 23.330 1.00 94.30 C ANISOU 5 CB HIS A 317 11151 11002 13676 -778 -35 2677 C ATOM 6 N MET A 318 0.013 -14.407 25.987 1.00 83.57 N ANISOU 6 N MET A 318 9746 9904 12105 -997 -172 2587 N ATOM 7 CA MET A 318 -0.440 -14.252 27.359 1.00 82.67 C ANISOU 7 CA MET A 318 9671 9925 11817 -1216 -277 2555 C ATOM 8 C MET A 318 -1.950 -14.448 27.457 1.00 79.56 C ANISOU 8 C MET A 318 9281 9823 11125 -1316 -218 2391 C ATOM 9 O MET A 318 -2.690 -14.295 26.482 1.00 77.39 O ANISOU 9 O MET A 318 8961 9669 10774 -1182 -87 2274 O ATOM 10 CB MET A 318 -0.054 -12.875 27.902 1.00 80.87 C ANISOU 10 CB MET A 318 9406 9693 11630 -1146 -302 2548 C ATOM 11 N GLU A 319 -2.400 -14.796 28.662 1.00 75.64 N ANISOU 11 N GLU A 319 8839 9437 10463 -1554 -316 2386 N ATOM 12 CA GLU A 319 -3.815 -14.981 28.944 1.00 72.97 C ANISOU 12 CA GLU A 319 8502 9379 9842 -1676 -271 2246 C ATOM 13 C GLU A 319 -4.350 -14.003 29.980 1.00 69.58 C ANISOU 13 C GLU A 319 8070 9135 9232 -1745 -292 2164 C ATOM 14 O GLU A 319 -5.526 -14.098 30.350 1.00 69.41 O ANISOU 14 O GLU A 319 8047 9357 8967 -1857 -256 2053 O ATOM 15 CB GLU A 319 -4.082 -16.418 29.417 1.00 78.85 C ANISOU 15 CB GLU A 319 9317 10124 10517 -1911 -353 2305 C ATOM 16 CG GLU A 319 -3.808 -17.489 28.371 1.00 81.65 C ANISOU 16 CG GLU A 319 9683 10337 11004 -1855 -328 2359 C ATOM 17 CD GLU A 319 -4.897 -17.577 27.316 1.00 81.03 C ANISOU 17 CD GLU A 319 9555 10427 10805 -1753 -194 2214 C ATOM 18 OE1 GLU A 319 -5.936 -16.900 27.468 1.00 79.12 O ANISOU 18 OE1 GLU A 319 9269 10428 10366 -1753 -124 2072 O ATOM 19 OE2 GLU A 319 -4.714 -18.328 26.335 1.00 82.29 O ANISOU 19 OE2 GLU A 319 9723 10475 11067 -1670 -163 2241 O ATOM 20 N LYS A 320 -3.528 -13.070 30.456 1.00 64.28 N ANISOU 20 N LYS A 320 7398 8355 8671 -1680 -351 2216 N ATOM 21 CA LYS A 320 -3.950 -12.123 31.483 1.00 62.62 C ANISOU 21 CA LYS A 320 7199 8301 8294 -1738 -386 2144 C ATOM 22 C LYS A 320 -4.919 -11.112 30.882 1.00 56.50 C ANISOU 22 C LYS A 320 6346 7746 7374 -1580 -242 1968 C ATOM 23 O LYS A 320 -4.535 -10.295 30.040 1.00 53.43 O ANISOU 23 O LYS A 320 5897 7286 7118 -1360 -169 1946 O ATOM 24 CB LYS A 320 -2.734 -11.424 32.085 1.00 63.56 C ANISOU 24 CB LYS A 320 7339 8215 8596 -1700 -502 2253 C ATOM 25 N ARG A 321 -6.175 -11.165 31.316 1.00 55.83 N ANISOU 25 N ARG A 321 6263 7930 7021 -1691 -200 1846 N ATOM 26 CA ARG A 321 -7.217 -10.252 30.846 1.00 52.13 C ANISOU 26 CA ARG A 321 5724 7696 6387 -1562 -68 1669 C ATOM 27 C ARG A 321 -7.691 -9.396 32.012 1.00 52.64 C ANISOU 27 C ARG A 321 5812 7931 6257 -1636 -108 1601 C ATOM 28 O ARG A 321 -8.542 -9.836 32.805 1.00 53.29 O ANISOU 28 O ARG A 321 5927 8199 6122 -1818 -123 1560 O ATOM 29 CB ARG A 321 -8.382 -11.031 30.238 1.00 52.61 C ANISOU 29 CB ARG A 321 5753 7939 6297 -1609 30 1573 C ATOM 30 CG ARG A 321 -8.006 -11.844 29.008 1.00 52.64 C ANISOU 30 CG ARG A 321 5740 7786 6475 -1514 74 1623 C ATOM 31 CD ARG A 321 -9.125 -12.793 28.614 1.00 54.20 C ANISOU 31 CD ARG A 321 5924 8146 6523 -1609 132 1546 C ATOM 32 NE ARG A 321 -8.868 -13.452 27.336 1.00 53.69 N ANISOU 32 NE ARG A 321 5846 7949 6606 -1486 183 1569 N ATOM 33 CZ ARG A 321 -8.180 -14.581 27.200 1.00 55.39 C ANISOU 33 CZ ARG A 321 6114 7967 6964 -1561 110 1700 C ATOM 34 NH1 ARG A 321 -7.671 -15.183 28.266 1.00 58.07 N ANISOU 34 NH1 ARG A 321 6522 8218 7324 -1764 -19 1822 N ATOM 35 NH2 ARG A 321 -7.998 -15.108 25.996 1.00 54.44 N ANISOU 35 NH2 ARG A 321 5985 7737 6964 -1428 164 1707 N ATOM 36 N PRO A 322 -7.177 -8.171 32.161 1.00 51.97 N ANISOU 36 N PRO A 322 5715 7793 6240 -1499 -126 1587 N ATOM 37 CA PRO A 322 -7.498 -7.372 33.352 1.00 55.03 C ANISOU 37 CA PRO A 322 6142 8313 6452 -1569 -187 1534 C ATOM 38 C PRO A 322 -8.864 -6.705 33.323 1.00 54.41 C ANISOU 38 C PRO A 322 6016 8546 6110 -1528 -70 1349 C ATOM 39 O PRO A 322 -9.319 -6.234 34.374 1.00 56.41 O ANISOU 39 O PRO A 322 6312 8946 6174 -1613 -112 1299 O ATOM 40 CB PRO A 322 -6.382 -6.320 33.366 1.00 54.63 C ANISOU 40 CB PRO A 322 6089 8065 6603 -1418 -252 1591 C ATOM 41 CG PRO A 322 -6.042 -6.138 31.925 1.00 51.02 C ANISOU 41 CG PRO A 322 5549 7499 6336 -1205 -144 1588 C ATOM 42 CD PRO A 322 -6.214 -7.490 31.277 1.00 49.94 C ANISOU 42 CD PRO A 322 5409 7332 6232 -1276 -101 1632 C ATOM 43 N PHE A 323 -9.530 -6.646 32.172 1.00 56.50 N ANISOU 43 N PHE A 323 6200 8915 6354 -1396 71 1245 N ATOM 44 CA PHE A 323 -10.810 -5.957 32.042 1.00 56.75 C ANISOU 44 CA PHE A 323 6176 9234 6153 -1336 187 1065 C ATOM 45 C PHE A 323 -11.932 -6.988 32.069 1.00 56.91 C ANISOU 45 C PHE A 323 6184 9450 5991 -1495 241 1015 C ATOM 46 O PHE A 323 -12.139 -7.718 31.095 1.00 55.78 O ANISOU 46 O PHE A 323 6001 9281 5913 -1465 305 1010 O ATOM 47 CB PHE A 323 -10.848 -5.129 30.760 1.00 54.58 C ANISOU 47 CB PHE A 323 5818 8952 5969 -1077 305 975 C ATOM 48 CG PHE A 323 -9.728 -4.135 30.651 1.00 54.44 C ANISOU 48 CG PHE A 323 5802 8732 6151 -916 257 1034 C ATOM 49 CD1 PHE A 323 -9.806 -2.910 31.291 1.00 57.41 C ANISOU 49 CD1 PHE A 323 6186 9187 6441 -857 229 966 C ATOM 50 CD2 PHE A 323 -8.590 -4.432 29.920 1.00 53.89 C ANISOU 50 CD2 PHE A 323 5725 8389 6360 -824 237 1161 C ATOM 51 CE1 PHE A 323 -8.774 -1.995 31.197 1.00 58.34 C ANISOU 51 CE1 PHE A 323 6303 9111 6753 -714 177 1025 C ATOM 52 CE2 PHE A 323 -7.554 -3.522 29.822 1.00 55.27 C ANISOU 52 CE2 PHE A 323 5893 8376 6733 -680 193 1224 C ATOM 53 CZ PHE A 323 -7.647 -2.302 30.461 1.00 57.04 C ANISOU 53 CZ PHE A 323 6122 8676 6875 -628 160 1157 C ATOM 54 N MET A 324 -12.657 -7.042 33.183 1.00 50.01 N ANISOU 54 N MET A 324 5345 8766 4890 -1661 214 980 N ATOM 55 CA MET A 324 -13.743 -7.989 33.371 1.00 52.63 C ANISOU 55 CA MET A 324 5663 9292 5042 -1833 259 942 C ATOM 56 C MET A 324 -15.091 -7.293 33.229 1.00 54.17 C ANISOU 56 C MET A 324 5783 9791 5008 -1769 384 761 C ATOM 57 O MET A 324 -15.235 -6.106 33.534 1.00 56.04 O ANISOU 57 O MET A 324 6012 10120 5159 -1660 404 677 O ATOM 58 CB MET A 324 -13.649 -8.661 34.743 1.00 57.63 C ANISOU 58 CB MET A 324 6388 9931 5577 -2078 148 1043 C ATOM 59 N CYS A 325 -16.082 -8.049 32.764 1.00 54.36 N ANISOU 59 N CYS A 325 5751 9967 4936 -1838 464 702 N ATOM 60 CA CYS A 325 -17.423 -7.514 32.580 1.00 55.90 C ANISOU 60 CA CYS A 325 5864 10455 4920 -1789 585 533 C ATOM 61 C CYS A 325 -18.165 -7.491 33.910 1.00 61.99 C ANISOU 61 C CYS A 325 6666 11442 5448 -1965 571 516 C ATOM 62 O CYS A 325 -18.168 -8.482 34.648 1.00 67.34 O ANISOU 62 O CYS A 325 7395 12107 6085 -2180 507 617 O ATOM 63 CB CYS A 325 -18.194 -8.348 31.558 1.00 54.95 C ANISOU 63 CB CYS A 325 5670 10406 4803 -1795 667 479 C ATOM 64 SG CYS A 325 -19.865 -7.752 31.236 1.00 57.48 S ANISOU 64 SG CYS A 325 5877 11079 4882 -1732 813 271 S ATOM 65 N ALA A 326 -18.797 -6.359 34.212 1.00 62.81 N ANISOU 65 N ALA A 326 6739 11742 5385 -1870 632 390 N ATOM 66 CA ALA A 326 -19.522 -6.178 35.462 1.00 70.96 C ANISOU 66 CA ALA A 326 7799 12990 6170 -2005 632 362 C ATOM 67 C ALA A 326 -20.983 -6.600 35.374 1.00 75.12 C ANISOU 67 C ALA A 326 8243 13765 6533 -2076 728 260 C ATOM 68 O ALA A 326 -21.724 -6.412 36.344 1.00 80.84 O ANISOU 68 O ALA A 326 8985 14598 7134 -2132 709 212 O ATOM 69 CB ALA A 326 -19.436 -4.717 35.914 1.00 72.95 C ANISOU 69 CB ALA A 326 8073 13309 6337 -1856 632 278 C ATOM 70 N TYR A 327 -21.413 -7.155 34.245 1.00 64.06 N ANISOU 70 N TYR A 327 6765 12344 5231 -2026 781 212 N ATOM 71 CA TYR A 327 -22.787 -7.618 34.125 1.00 67.44 C ANISOU 71 CA TYR A 327 7127 12882 5615 -2056 806 112 C ATOM 72 C TYR A 327 -23.023 -8.794 35.070 1.00 72.68 C ANISOU 72 C TYR A 327 7829 13591 6197 -2322 758 221 C ATOM 73 O TYR A 327 -22.169 -9.680 35.184 1.00 70.58 O ANISOU 73 O TYR A 327 7618 13221 5978 -2478 714 377 O ATOM 74 CB TYR A 327 -23.090 -8.029 32.683 1.00 65.02 C ANISOU 74 CB TYR A 327 6749 12529 5428 -1953 857 52 C ATOM 75 CG TYR A 327 -24.517 -8.467 32.439 1.00 69.85 C ANISOU 75 CG TYR A 327 7289 13253 6000 -1976 878 -51 C ATOM 76 CD1 TYR A 327 -25.516 -7.536 32.184 1.00 71.66 C ANISOU 76 CD1 TYR A 327 7464 13552 6211 -1809 906 -205 C ATOM 77 CD2 TYR A 327 -24.865 -9.812 32.455 1.00 73.73 C ANISOU 77 CD2 TYR A 327 7766 13769 6478 -2171 862 18 C ATOM 78 CE1 TYR A 327 -26.822 -7.931 31.957 1.00 75.65 C ANISOU 78 CE1 TYR A 327 7898 14159 6684 -1839 921 -285 C ATOM 79 CE2 TYR A 327 -26.167 -10.217 32.229 1.00 78.73 C ANISOU 79 CE2 TYR A 327 8328 14515 7072 -2199 879 -69 C ATOM 80 CZ TYR A 327 -27.141 -9.273 31.980 1.00 79.38 C ANISOU 80 CZ TYR A 327 8352 14674 7134 -2033 910 -219 C ATOM 81 OH TYR A 327 -28.438 -9.673 31.755 1.00 84.90 O ANISOU 81 OH TYR A 327 8974 15485 7797 -2069 924 -295 O ATOM 82 N PRO A 328 -24.157 -8.825 35.769 1.00 78.13 N ANISOU 82 N PRO A 328 8490 14419 6778 -2380 763 154 N ATOM 83 CA PRO A 328 -24.412 -9.909 36.732 1.00 84.76 C ANISOU 83 CA PRO A 328 9367 15304 7536 -2628 719 257 C ATOM 84 C PRO A 328 -24.453 -11.267 36.049 1.00 84.83 C ANISOU 84 C PRO A 328 9350 15259 7622 -2758 712 328 C ATOM 85 O PRO A 328 -25.244 -11.499 35.132 1.00 86.23 O ANISOU 85 O PRO A 328 9442 15482 7842 -2692 756 237 O ATOM 86 CB PRO A 328 -25.772 -9.533 37.333 1.00 91.48 C ANISOU 86 CB PRO A 328 10160 16322 8278 -2610 752 146 C ATOM 87 CG PRO A 328 -25.899 -8.061 37.102 1.00 88.95 C ANISOU 87 CG PRO A 328 9816 16015 7966 -2372 786 18 C ATOM 88 CD PRO A 328 -25.217 -7.802 35.794 1.00 81.10 C ANISOU 88 CD PRO A 328 8804 14902 7107 -2220 805 -7 C ATOM 89 N GLY A 329 -23.587 -12.171 36.507 1.00 82.50 N ANISOU 89 N GLY A 329 9137 14854 7354 -2945 644 497 N ATOM 90 CA GLY A 329 -23.516 -13.512 35.973 1.00 83.52 C ANISOU 90 CA GLY A 329 9260 14900 7574 -3083 619 585 C ATOM 91 C GLY A 329 -22.592 -13.686 34.788 1.00 77.23 C ANISOU 91 C GLY A 329 8459 13935 6949 -3001 626 634 C ATOM 92 O GLY A 329 -22.351 -14.828 34.375 1.00 78.54 O ANISOU 92 O GLY A 329 8634 13992 7216 -3118 588 727 O ATOM 93 N CYS A 330 -22.066 -12.600 34.228 1.00 82.69 N ANISOU 93 N CYS A 330 9137 14595 7688 -2797 670 576 N ATOM 94 CA CYS A 330 -21.180 -12.676 33.075 1.00 75.10 C ANISOU 94 CA CYS A 330 8180 13407 6947 -2649 652 599 C ATOM 95 C CYS A 330 -19.732 -12.765 33.540 1.00 72.98 C ANISOU 95 C CYS A 330 8027 12866 6836 -2664 530 747 C ATOM 96 O CYS A 330 -19.300 -11.992 34.401 1.00 75.45 O ANISOU 96 O CYS A 330 8395 13177 7097 -2650 493 767 O ATOM 97 CB CYS A 330 -21.373 -11.461 32.168 1.00 69.12 C ANISOU 97 CB CYS A 330 7353 12709 6199 -2383 745 449 C ATOM 98 SG CYS A 330 -20.447 -11.539 30.620 1.00 62.51 S ANISOU 98 SG CYS A 330 6515 11602 5633 -2166 739 460 S ATOM 99 N ASN A 331 -18.986 -13.711 32.967 1.00 61.42 N ANISOU 99 N ASN A 331 6599 11170 5566 -2690 463 850 N ATOM 100 CA ASN A 331 -17.595 -13.944 33.333 1.00 60.32 C ANISOU 100 CA ASN A 331 6563 10757 5599 -2712 342 1001 C ATOM 101 C ASN A 331 -16.627 -13.549 32.223 1.00 54.92 C ANISOU 101 C ASN A 331 5875 9848 5144 -2484 343 1007 C ATOM 102 O ASN A 331 -15.483 -14.014 32.210 1.00 53.67 O ANISOU 102 O ASN A 331 5786 9435 5172 -2497 250 1140 O ATOM 103 CB ASN A 331 -17.389 -15.409 33.718 1.00 63.50 C ANISOU 103 CB ASN A 331 7026 11053 6048 -2941 251 1140 C ATOM 104 N LYS A 332 -17.060 -12.699 31.295 1.00 63.84 N ANISOU 104 N LYS A 332 6925 11066 6264 -2274 449 870 N ATOM 105 CA LYS A 332 -16.201 -12.297 30.189 1.00 58.39 C ANISOU 105 CA LYS A 332 6227 10174 5783 -2045 465 874 C ATOM 106 C LYS A 332 -15.061 -11.413 30.678 1.00 55.99 C ANISOU 106 C LYS A 332 5976 9712 5587 -1958 403 943 C ATOM 107 O LYS A 332 -15.256 -10.509 31.495 1.00 57.06 O ANISOU 107 O LYS A 332 6117 9968 5595 -1960 403 897 O ATOM 108 CB LYS A 332 -17.013 -11.557 29.125 1.00 57.13 C ANISOU 108 CB LYS A 332 5974 10164 5570 -1842 596 705 C ATOM 109 CG LYS A 332 -17.951 -12.441 28.318 1.00 58.98 C ANISOU 109 CG LYS A 332 6154 10493 5761 -1879 649 640 C ATOM 110 CD LYS A 332 -17.186 -13.389 27.410 1.00 58.29 C ANISOU 110 CD LYS A 332 6106 10157 5886 -1838 606 732 C ATOM 111 CE LYS A 332 -18.137 -14.204 26.547 1.00 60.89 C ANISOU 111 CE LYS A 332 6386 10576 6174 -1855 651 655 C ATOM 112 NZ LYS A 332 -17.409 -15.078 25.587 1.00 59.64 N ANISOU 112 NZ LYS A 332 6271 10174 6213 -1788 612 734 N ATOM 113 N ARG A 333 -13.860 -11.686 30.172 1.00 50.27 N ANISOU 113 N ARG A 333 5290 8710 5100 -1880 348 1056 N ATOM 114 CA ARG A 333 -12.679 -10.883 30.448 1.00 49.05 C ANISOU 114 CA ARG A 333 5174 8371 5094 -1777 287 1132 C ATOM 115 C ARG A 333 -11.957 -10.605 29.138 1.00 43.10 C ANISOU 115 C ARG A 333 4387 7431 4560 -1540 337 1142 C ATOM 116 O ARG A 333 -12.001 -11.414 28.207 1.00 45.69 O ANISOU 116 O ARG A 333 4702 7689 4970 -1506 371 1153 O ATOM 117 CB ARG A 333 -11.735 -11.585 31.435 1.00 53.68 C ANISOU 117 CB ARG A 333 5854 8773 5768 -1957 139 1304 C ATOM 118 CG ARG A 333 -12.374 -11.935 32.768 1.00 61.25 C ANISOU 118 CG ARG A 333 6860 9898 6513 -2196 85 1311 C ATOM 119 CD ARG A 333 -11.368 -12.578 33.706 1.00 66.97 C ANISOU 119 CD ARG A 333 7687 10424 7336 -2357 -66 1482 C ATOM 120 NE ARG A 333 -10.288 -11.662 34.059 1.00 67.12 N ANISOU 120 NE ARG A 333 7740 10277 7486 -2253 -140 1538 N ATOM 121 CZ ARG A 333 -10.294 -10.882 35.136 1.00 70.78 C ANISOU 121 CZ ARG A 333 8247 10815 7832 -2292 -193 1522 C ATOM 122 NH1 ARG A 333 -11.326 -10.908 35.968 1.00 75.23 N ANISOU 122 NH1 ARG A 333 8824 11622 8137 -2429 -170 1454 N ATOM 123 NH2 ARG A 333 -9.269 -10.078 35.380 1.00 69.70 N ANISOU 123 NH2 ARG A 333 8139 10506 7838 -2192 -271 1577 N ATOM 124 N TYR A 334 -11.294 -9.452 29.067 1.00 45.36 N ANISOU 124 N TYR A 334 4662 7634 4940 -1372 342 1139 N ATOM 125 CA TYR A 334 -10.678 -9.007 27.825 1.00 43.25 C ANISOU 125 CA TYR A 334 4354 7213 4865 -1126 409 1139 C ATOM 126 C TYR A 334 -9.328 -8.364 28.108 1.00 43.73 C ANISOU 126 C TYR A 334 4443 7042 5132 -1045 332 1258 C ATOM 127 O TYR A 334 -9.052 -7.906 29.220 1.00 44.49 O ANISOU 127 O TYR A 334 4577 7141 5184 -1138 243 1292 O ATOM 128 CB TYR A 334 -11.591 -8.030 27.071 1.00 41.04 C ANISOU 128 CB TYR A 334 3997 7129 4469 -941 545 961 C ATOM 129 CG TYR A 334 -12.917 -8.640 26.679 1.00 41.58 C ANISOU 129 CG TYR A 334 4027 7417 4356 -1002 622 841 C ATOM 130 CD1 TYR A 334 -13.055 -9.339 25.487 1.00 40.21 C ANISOU 130 CD1 TYR A 334 3833 7185 4260 -916 680 827 C ATOM 131 CD2 TYR A 334 -14.026 -8.531 27.507 1.00 42.74 C ANISOU 131 CD2 TYR A 334 4157 7825 4256 -1145 632 746 C ATOM 132 CE1 TYR A 334 -14.262 -9.906 25.127 1.00 41.23 C ANISOU 132 CE1 TYR A 334 3926 7506 4235 -975 737 718 C ATOM 133 CE2 TYR A 334 -15.238 -9.094 27.156 1.00 45.64 C ANISOU 133 CE2 TYR A 334 4479 8390 4471 -1207 698 644 C ATOM 134 CZ TYR A 334 -15.350 -9.780 25.965 1.00 45.25 C ANISOU 134 CZ TYR A 334 4409 8272 4511 -1124 746 629 C ATOM 135 OH TYR A 334 -16.554 -10.343 25.611 1.00 49.04 O ANISOU 135 OH TYR A 334 4843 8941 4850 -1187 800 527 O ATOM 136 N PHE A 335 -8.485 -8.336 27.072 1.00 45.38 N ANISOU 136 N PHE A 335 4631 7043 5568 -866 368 1322 N ATOM 137 CA PHE A 335 -7.150 -7.764 27.197 1.00 46.46 C ANISOU 137 CA PHE A 335 4779 6939 5933 -774 302 1446 C ATOM 138 C PHE A 335 -7.166 -6.242 27.163 1.00 46.61 C ANISOU 138 C PHE A 335 4753 7018 5939 -604 348 1362 C ATOM 139 O PHE A 335 -6.287 -5.605 27.756 1.00 47.12 O ANISOU 139 O PHE A 335 4834 6945 6122 -591 260 1444 O ATOM 140 CB PHE A 335 -6.241 -8.287 26.082 1.00 43.08 C ANISOU 140 CB PHE A 335 4342 6269 5757 -636 335 1552 C ATOM 141 CG PHE A 335 -5.966 -9.761 26.158 1.00 44.61 C ANISOU 141 CG PHE A 335 4591 6351 6008 -794 267 1662 C ATOM 142 CD1 PHE A 335 -4.901 -10.242 26.901 1.00 46.24 C ANISOU 142 CD1 PHE A 335 4853 6351 6366 -915 132 1828 C ATOM 143 CD2 PHE A 335 -6.763 -10.665 25.477 1.00 45.87 C ANISOU 143 CD2 PHE A 335 4749 6606 6075 -818 331 1598 C ATOM 144 CE1 PHE A 335 -4.641 -11.598 26.971 1.00 49.06 C ANISOU 144 CE1 PHE A 335 5264 6602 6776 -1058 67 1928 C ATOM 145 CE2 PHE A 335 -6.508 -12.023 25.542 1.00 49.10 C ANISOU 145 CE2 PHE A 335 5212 6905 6537 -962 262 1699 C ATOM 146 CZ PHE A 335 -5.446 -12.489 26.290 1.00 50.76 C ANISOU 146 CZ PHE A 335 5479 6913 6895 -1082 132 1864 C ATOM 147 N LYS A 336 -8.137 -5.644 26.476 1.00 48.66 N ANISOU 147 N LYS A 336 4955 7472 6061 -473 475 1201 N ATOM 148 CA LYS A 336 -8.186 -4.203 26.289 1.00 48.89 C ANISOU 148 CA LYS A 336 4938 7557 6081 -290 530 1114 C ATOM 149 C LYS A 336 -9.558 -3.672 26.675 1.00 51.46 C ANISOU 149 C LYS A 336 5242 8195 6116 -327 585 932 C ATOM 150 O LYS A 336 -10.572 -4.363 26.541 1.00 52.54 O ANISOU 150 O LYS A 336 5370 8508 6086 -416 635 851 O ATOM 151 CB LYS A 336 -7.866 -3.819 24.837 1.00 46.73 C ANISOU 151 CB LYS A 336 4608 7180 5966 -30 649 1101 C ATOM 152 CG LYS A 336 -6.442 -4.144 24.414 1.00 47.04 C ANISOU 152 CG LYS A 336 4658 6906 6307 43 609 1283 C ATOM 153 CD LYS A 336 -6.236 -3.913 22.927 1.00 45.74 C ANISOU 153 CD LYS A 336 4445 6657 6276 297 744 1269 C ATOM 154 CE LYS A 336 -4.772 -4.065 22.545 1.00 45.20 C ANISOU 154 CE LYS A 336 4378 6279 6517 389 712 1457 C ATOM 155 NZ LYS A 336 -4.222 -5.391 22.942 1.00 47.28 N ANISOU 155 NZ LYS A 336 4698 6401 6866 212 614 1595 N ATOM 156 N LEU A 337 -9.575 -2.427 27.160 1.00 54.60 N ANISOU 156 N LEU A 337 7420 6086 7239 -1247 -690 1174 N ATOM 157 CA LEU A 337 -10.834 -1.794 27.539 1.00 56.60 C ANISOU 157 CA LEU A 337 8072 6715 6720 -891 -710 825 C ATOM 158 C LEU A 337 -11.759 -1.633 26.341 1.00 53.69 C ANISOU 158 C LEU A 337 7607 6802 5989 -385 -362 444 C ATOM 159 O LEU A 337 -12.984 -1.735 26.482 1.00 54.04 O ANISOU 159 O LEU A 337 7649 7289 5594 -114 -264 117 O ATOM 160 CB LEU A 337 -10.562 -0.436 28.190 1.00 62.96 C ANISOU 160 CB LEU A 337 9567 7176 7177 -878 -1032 998 C ATOM 161 CG LEU A 337 -11.783 0.386 28.609 1.00 67.62 C ANISOU 161 CG LEU A 337 10641 8052 6999 -483 -1007 670 C ATOM 162 CD1 LEU A 337 -12.596 -0.354 29.659 1.00 67.24 C ANISOU 162 CD1 LEU A 337 10529 8263 6755 -602 -1007 501 C ATOM 163 CD2 LEU A 337 -11.362 1.757 29.116 1.00 75.47 C ANISOU 163 CD2 LEU A 337 12352 8622 7699 -482 -1299 854 C ATOM 164 N SER A 338 -11.196 -1.385 25.156 1.00 51.61 N ANISOU 164 N SER A 338 7269 6424 5918 -269 -180 509 N ATOM 165 CA SER A 338 -12.018 -1.259 23.957 1.00 51.01 C ANISOU 165 CA SER A 338 7138 6753 5492 150 106 181 C ATOM 166 C SER A 338 -12.750 -2.560 23.655 1.00 45.01 C ANISOU 166 C SER A 338 5888 6412 4802 138 330 -98 C ATOM 167 O SER A 338 -13.897 -2.542 23.191 1.00 46.89 O ANISOU 167 O SER A 338 6105 7097 4614 462 433 -410 O ATOM 168 CB SER A 338 -11.151 -0.841 22.769 1.00 55.45 C ANISOU 168 CB SER A 338 7740 7061 6267 202 278 336 C ATOM 169 OG SER A 338 -10.480 0.380 23.031 1.00 61.91 O ANISOU 169 OG SER A 338 8999 7487 7038 211 45 614 O ATOM 170 N HIS A 339 -12.105 -3.700 23.913 1.00 46.52 N ANISOU 170 N HIS A 339 5669 6444 5564 -247 387 38 N ATOM 171 CA HIS A 339 -12.764 -4.985 23.699 1.00 42.29 C ANISOU 171 CA HIS A 339 4673 6270 5126 -295 578 -216 C ATOM 172 C HIS A 339 -13.909 -5.187 24.683 1.00 40.48 C ANISOU 172 C HIS A 339 4428 6411 4542 -223 422 -403 C ATOM 173 O HIS A 339 -14.952 -5.747 24.324 1.00 40.65 O ANISOU 173 O HIS A 339 4220 6879 4347 -46 548 -698 O ATOM 174 CB HIS A 339 -11.749 -6.122 23.815 1.00 39.70 C ANISOU 174 CB HIS A 339 3907 5625 5550 -728 678 5 C ATOM 175 CG HIS A 339 -10.669 -6.078 22.780 1.00 41.62 C ANISOU 175 CG HIS A 339 4096 5503 6213 -783 949 181 C ATOM 176 ND1 HIS A 339 -9.540 -6.865 22.850 1.00 42.04 N ANISOU 176 ND1 HIS A 339 3787 5135 7052 -1150 1071 479 N ATOM 177 CD2 HIS A 339 -10.548 -5.346 21.647 1.00 44.67 C ANISOU 177 CD2 HIS A 339 4743 5866 6364 -518 1149 119 C ATOM 178 CE1 HIS A 339 -8.768 -6.617 21.807 1.00 44.87 C ANISOU 178 CE1 HIS A 339 4182 5216 7651 -1091 1382 588 C ATOM 179 NE2 HIS A 339 -9.357 -5.699 21.061 1.00 46.05 N ANISOU 179 NE2 HIS A 339 4729 5609 7161 -719 1428 367 N ATOM 180 N LEU A 340 -13.733 -4.740 25.929 1.00 40.15 N ANISOU 180 N LEU A 340 4650 6168 4435 -375 150 -221 N ATOM 181 CA LEU A 340 -14.793 -4.880 26.923 1.00 41.33 C ANISOU 181 CA LEU A 340 4845 6628 4229 -308 61 -384 C ATOM 182 C LEU A 340 -15.965 -3.959 26.608 1.00 48.44 C ANISOU 182 C LEU A 340 6027 7866 4511 206 139 -643 C ATOM 183 O LEU A 340 -17.128 -4.376 26.665 1.00 49.60 O ANISOU 183 O LEU A 340 5960 8447 4439 404 245 -882 O ATOM 184 CB LEU A 340 -14.243 -4.597 28.321 1.00 42.50 C ANISOU 184 CB LEU A 340 5312 6418 4416 -640 -240 -114 C ATOM 185 CG LEU A 340 -15.270 -4.620 29.455 1.00 47.39 C ANISOU 185 CG LEU A 340 6103 7289 4614 -586 -291 -263 C ATOM 186 CD1 LEU A 340 -15.978 -5.965 29.512 1.00 44.65 C ANISOU 186 CD1 LEU A 340 5182 7344 4441 -663 -145 -436 C ATOM 187 CD2 LEU A 340 -14.610 -4.301 30.788 1.00 51.76 C ANISOU 187 CD2 LEU A 340 7088 7423 5157 -978 -612 22 C ATOM 188 N GLN A 341 -15.677 -2.696 26.279 1.00 48.69 N ANISOU 188 N GLN A 341 6514 7686 4302 426 81 -569 N ATOM 189 CA GLN A 341 -16.741 -1.762 25.925 1.00 56.61 C ANISOU 189 CA GLN A 341 7765 8962 4782 925 153 -776 C ATOM 190 C GLN A 341 -17.504 -2.228 24.693 1.00 55.16 C ANISOU 190 C GLN A 341 7213 9201 4545 1172 339 -1004 C ATOM 191 O GLN A 341 -18.706 -1.967 24.570 1.00 59.70 O ANISOU 191 O GLN A 341 7759 10133 4789 1525 395 -1189 O ATOM 192 CB GLN A 341 -16.160 -0.366 25.697 1.00 62.18 C ANISOU 192 CB GLN A 341 9002 9319 5305 1080 43 -627 C ATOM 193 CG GLN A 341 -15.545 0.258 26.939 1.00 67.95 C ANISOU 193 CG GLN A 341 10215 9619 5984 854 -195 -412 C ATOM 194 CD GLN A 341 -14.853 1.576 26.650 1.00 74.93 C ANISOU 194 CD GLN A 341 11603 10116 6753 960 -335 -234 C ATOM 195 OE1 GLN A 341 -14.612 1.923 25.494 1.00 75.79 O ANISOU 195 OE1 GLN A 341 11649 10237 6911 1139 -249 -223 O ATOM 196 NE2 GLN A 341 -14.528 2.317 27.703 1.00 80.84 N ANISOU 196 NE2 GLN A 341 12890 10503 7323 829 -560 -89 N ATOM 197 N ARG A 342 -16.824 -2.918 23.775 1.00 55.24 N ANISOU 197 N ARG A 342 6955 9146 4886 980 441 -976 N ATOM 198 CA ARG A 342 -17.503 -3.486 22.617 1.00 55.34 C ANISOU 198 CA ARG A 342 6677 9526 4823 1131 594 -1197 C ATOM 199 C ARG A 342 -18.386 -4.664 23.013 1.00 53.38 C ANISOU 199 C ARG A 342 5982 9651 4651 1046 627 -1367 C ATOM 200 O ARG A 342 -19.444 -4.875 22.410 1.00 54.19 O ANISOU 200 O ARG A 342 5919 10079 4593 1241 632 -1521 O ATOM 201 CB ARG A 342 -16.467 -3.909 21.575 1.00 53.37 C ANISOU 201 CB ARG A 342 6346 9040 4893 924 756 -1128 C ATOM 202 CG ARG A 342 -17.034 -4.290 20.222 1.00 57.75 C ANISOU 202 CG ARG A 342 6785 9889 5268 1061 906 -1347 C ATOM 203 CD ARG A 342 -15.911 -4.508 19.219 1.00 55.92 C ANISOU 203 CD ARG A 342 6606 9339 5302 879 1139 -1265 C ATOM 204 NE ARG A 342 -14.951 -5.503 19.689 1.00 46.04 N ANISOU 204 NE ARG A 342 5054 7790 4648 487 1267 -1131 N ATOM 205 CZ ARG A 342 -13.825 -5.816 19.057 1.00 46.34 C ANISOU 205 CZ ARG A 342 5062 7459 5087 285 1528 -999 C ATOM 206 NH1 ARG A 342 -13.507 -5.209 17.921 1.00 50.67 N ANISOU 206 NH1 ARG A 342 5905 7901 5448 428 1704 -1001 N ATOM 207 NH2 ARG A 342 -13.015 -6.735 19.563 1.00 42.55 N ANISOU 207 NH2 ARG A 342 4250 6697 5222 -62 1631 -843 N ATOM 208 N HIS A 343 -17.974 -5.431 24.026 1.00 49.74 N ANISOU 208 N HIS A 343 5328 9060 4510 707 588 -1269 N ATOM 209 CA HIS A 343 -18.786 -6.549 24.496 1.00 52.57 C ANISOU 209 CA HIS A 343 5258 9757 4959 607 609 -1405 C ATOM 210 C HIS A 343 -20.023 -6.077 25.249 1.00 53.82 C ANISOU 210 C HIS A 343 5496 10216 4738 904 566 -1496 C ATOM 211 O HIS A 343 -21.063 -6.744 25.205 1.00 52.96 O ANISOU 211 O HIS A 343 5071 10378 4674 957 552 -1583 O ATOM 212 CB HIS A 343 -17.950 -7.464 25.392 1.00 54.97 C ANISOU 212 CB HIS A 343 5347 9807 5731 141 561 -1236 C ATOM 213 CG HIS A 343 -18.766 -8.317 26.314 1.00 62.84 C ANISOU 213 CG HIS A 343 6033 11094 6750 38 528 -1312 C ATOM 214 ND1 HIS A 343 -19.482 -9.412 25.879 1.00 64.55 N ANISOU 214 ND1 HIS A 343 5791 11654 7083 17 610 -1490 N ATOM 215 CD2 HIS A 343 -18.984 -8.231 27.648 1.00 66.39 C ANISOU 215 CD2 HIS A 343 6605 11518 7102 -65 421 -1222 C ATOM 216 CE1 HIS A 343 -20.103 -9.965 26.906 1.00 66.45 C ANISOU 216 CE1 HIS A 343 5936 11973 7339 -84 518 -1457 C ATOM 217 NE2 HIS A 343 -19.818 -9.268 27.991 1.00 68.46 N ANISOU 217 NE2 HIS A 343 6438 12131 7443 -131 467 -1340 N ATOM 218 N SER A 344 -19.932 -4.936 25.938 1.00 57.67 N ANISOU 218 N SER A 344 6450 10498 4966 1055 501 -1398 N ATOM 219 CA SER A 344 -21.033 -4.466 26.773 1.00 65.06 C ANISOU 219 CA SER A 344 7513 11565 5641 1306 519 -1434 C ATOM 220 C SER A 344 -22.313 -4.235 25.981 1.00 70.02 C ANISOU 220 C SER A 344 7969 12356 6281 1623 513 -1464 C ATOM 221 O SER A 344 -23.402 -4.273 26.563 1.00 74.00 O ANISOU 221 O SER A 344 8361 13007 6749 1767 551 -1473 O ATOM 222 CB SER A 344 -20.631 -3.178 27.494 1.00 71.22 C ANISOU 222 CB SER A 344 8920 12018 6123 1413 472 -1335 C ATOM 223 OG SER A 344 -20.346 -2.143 26.570 1.00 78.16 O ANISOU 223 OG SER A 344 10071 12701 6925 1630 432 -1282 O ATOM 224 N ARG A 345 -22.212 -4.001 24.671 1.00 59.94 N ANISOU 224 N ARG A 345 6673 11083 5018 1721 468 -1475 N ATOM 225 CA ARG A 345 -23.405 -3.814 23.857 1.00 67.49 C ANISOU 225 CA ARG A 345 7456 12274 5913 1991 406 -1503 C ATOM 226 C ARG A 345 -24.188 -5.105 23.656 1.00 65.40 C ANISOU 226 C ARG A 345 6703 12347 5799 1868 358 -1588 C ATOM 227 O ARG A 345 -25.339 -5.047 23.210 1.00 74.35 O ANISOU 227 O ARG A 345 7646 13758 6844 2092 286 -1609 O ATOM 228 CB ARG A 345 -23.027 -3.216 22.501 1.00 72.86 C ANISOU 228 CB ARG A 345 8306 12877 6501 2093 357 -1492 C ATOM 229 CG ARG A 345 -22.540 -1.781 22.578 1.00 77.97 C ANISOU 229 CG ARG A 345 9428 13223 6973 2283 358 -1392 C ATOM 230 CD ARG A 345 -22.438 -1.154 21.199 1.00 85.44 C ANISOU 230 CD ARG A 345 10509 14151 7802 2425 298 -1371 C ATOM 231 NE ARG A 345 -22.470 0.304 21.268 1.00 94.20 N ANISOU 231 NE ARG A 345 11990 15068 8732 2709 262 -1275 N ATOM 232 CZ ARG A 345 -22.482 1.103 20.206 1.00101.20 C ANISOU 232 CZ ARG A 345 13042 15930 9478 2893 194 -1231 C ATOM 233 NH1 ARG A 345 -22.462 0.587 18.985 1.00102.64 N ANISOU 233 NH1 ARG A 345 13098 16258 9641 2801 164 -1280 N ATOM 234 NH2 ARG A 345 -22.515 2.419 20.365 1.00107.88 N ANISOU 234 NH2 ARG A 345 14214 16593 10184 3159 159 -1141 N ATOM 235 N LYS A 346 -23.598 -6.261 23.970 1.00 62.24 N ANISOU 235 N LYS A 346 6092 11940 5616 1515 383 -1632 N ATOM 236 CA LYS A 346 -24.327 -7.517 23.843 1.00 66.10 C ANISOU 236 CA LYS A 346 6182 12683 6248 1355 309 -1704 C ATOM 237 C LYS A 346 -25.398 -7.654 24.918 1.00 72.21 C ANISOU 237 C LYS A 346 6825 13609 7002 1449 312 -1663 C ATOM 238 O LYS A 346 -26.463 -8.226 24.661 1.00 75.10 O ANISOU 238 O LYS A 346 6949 14213 7372 1487 235 -1689 O ATOM 239 CB LYS A 346 -23.356 -8.697 23.901 1.00 61.26 C ANISOU 239 CB LYS A 346 5434 11927 5914 937 347 -1741 C ATOM 240 CG LYS A 346 -24.017 -10.057 23.737 1.00 65.47 C ANISOU 240 CG LYS A 346 5711 12574 6590 731 267 -1803 C ATOM 241 CD LYS A 346 -22.991 -11.179 23.763 1.00 61.53 C ANISOU 241 CD LYS A 346 5187 11773 6419 346 335 -1794 C ATOM 242 CE LYS A 346 -23.658 -12.538 23.624 1.00 64.89 C ANISOU 242 CE LYS A 346 5498 12182 6977 183 288 -1822 C ATOM 243 NZ LYS A 346 -24.426 -12.650 22.355 1.00 72.72 N ANISOU 243 NZ LYS A 346 6398 13458 7776 294 218 -1974 N ATOM 244 N HIS A 347 -25.141 -7.135 26.120 1.00 62.45 N ANISOU 244 N HIS A 347 5787 12224 5717 1481 425 -1600 N ATOM 245 CA HIS A 347 -26.130 -7.206 27.191 1.00 70.52 C ANISOU 245 CA HIS A 347 6738 13350 6708 1579 505 -1559 C ATOM 246 C HIS A 347 -27.280 -6.235 26.966 1.00 78.20 C ANISOU 246 C HIS A 347 7772 14422 7517 2002 555 -1520 C ATOM 247 O HIS A 347 -28.428 -6.545 27.302 1.00 84.78 O ANISOU 247 O HIS A 347 8387 15434 8393 2107 603 -1487 O ATOM 248 CB HIS A 347 -25.471 -6.927 28.538 1.00 73.73 C ANISOU 248 CB HIS A 347 7415 13566 7035 1464 645 -1527 C ATOM 249 CG HIS A 347 -24.397 -7.905 28.890 1.00 71.69 C ANISOU 249 CG HIS A 347 7014 13277 6947 1037 604 -1545 C ATOM 250 ND1 HIS A 347 -24.633 -9.257 29.007 1.00 71.02 N ANISOU 250 ND1 HIS A 347 6563 13304 7116 758 526 -1551 N ATOM 251 CD2 HIS A 347 -23.078 -7.730 29.142 1.00 68.14 C ANISOU 251 CD2 HIS A 347 6761 12668 6459 813 621 -1535 C ATOM 252 CE1 HIS A 347 -23.508 -9.874 29.320 1.00 64.94 C ANISOU 252 CE1 HIS A 347 5728 12419 6527 385 507 -1530 C ATOM 253 NE2 HIS A 347 -22.550 -8.969 29.409 1.00 64.56 N ANISOU 253 NE2 HIS A 347 5937 12283 6308 400 587 -1526 N ATOM 254 N THR A 348 -26.996 -5.057 26.409 1.00 73.48 N ANISOU 254 N THR A 348 7472 13692 6757 2246 557 -1503 N ATOM 255 CA THR A 348 -28.056 -4.093 26.147 1.00 81.80 C ANISOU 255 CA THR A 348 8563 14843 7673 2665 605 -1455 C ATOM 256 C THR A 348 -28.902 -4.487 24.949 1.00 83.69 C ANISOU 256 C THR A 348 8431 15443 7924 2780 442 -1473 C ATOM 257 O THR A 348 -29.977 -3.912 24.750 1.00 93.30 O ANISOU 257 O THR A 348 9547 16824 9078 3122 475 -1410 O ATOM 258 CB THR A 348 -27.469 -2.699 25.922 1.00 84.20 C ANISOU 258 CB THR A 348 9331 14868 7793 2876 633 -1422 C ATOM 259 OG1 THR A 348 -26.638 -2.716 24.756 1.00 79.35 O ANISOU 259 OG1 THR A 348 8752 14225 7171 2773 474 -1450 O ATOM 260 CG2 THR A 348 -26.650 -2.270 27.124 1.00 81.33 C ANISOU 260 CG2 THR A 348 9409 14136 7357 2733 772 -1408 C ATOM 261 N GLY A 349 -28.433 -5.433 24.139 1.00 92.11 N ANISOU 261 N GLY A 349 8693 17541 8763 1567 1968 1037 N ATOM 262 CA GLY A 349 -29.155 -5.842 22.952 1.00 85.98 C ANISOU 262 CA GLY A 349 7871 16649 8146 1434 2009 1021 C ATOM 263 C GLY A 349 -29.348 -4.773 21.900 1.00 78.05 C ANISOU 263 C GLY A 349 6863 15565 7229 1556 1899 779 C ATOM 264 O GLY A 349 -30.090 -4.997 20.937 1.00 73.36 O ANISOU 264 O GLY A 349 6214 14911 6750 1457 1921 742 O ATOM 265 N GLU A 350 -28.699 -3.623 22.036 1.00 83.50 N ANISOU 265 N GLU A 350 7617 16241 7870 1764 1774 611 N ATOM 266 CA GLU A 350 -28.898 -2.547 21.080 1.00 76.91 C ANISOU 266 CA GLU A 350 6796 15314 7115 1887 1651 366 C ATOM 267 C GLU A 350 -28.069 -2.796 19.829 1.00 65.54 C ANISOU 267 C GLU A 350 5528 13474 5900 1811 1597 389 C ATOM 268 O GLU A 350 -26.867 -3.069 19.912 1.00 61.38 O ANISOU 268 O GLU A 350 5152 12735 5436 1802 1576 494 O ATOM 269 CB GLU A 350 -28.529 -1.204 21.702 1.00 79.66 C ANISOU 269 CB GLU A 350 7192 15727 7347 2113 1505 172 C ATOM 270 N LYS A 351 -28.720 -2.713 18.671 1.00 77.54 N ANISOU 270 N LYS A 351 7038 14869 7554 1746 1564 293 N ATOM 271 CA LYS A 351 -28.065 -2.825 17.368 1.00 68.19 C ANISOU 271 CA LYS A 351 6037 13280 6591 1669 1497 279 C ATOM 272 C LYS A 351 -28.496 -1.633 16.523 1.00 63.95 C ANISOU 272 C LYS A 351 5512 12693 6095 1797 1355 11 C ATOM 273 O LYS A 351 -29.433 -1.728 15.720 1.00 64.00 O ANISOU 273 O LYS A 351 5456 12689 6174 1713 1351 -44 O ATOM 274 CB LYS A 351 -28.400 -4.158 16.695 1.00 67.71 C ANISOU 274 CB LYS A 351 5986 13072 6670 1410 1612 472 C ATOM 275 CG LYS A 351 -27.946 -5.368 17.508 1.00 73.58 C ANISOU 275 CG LYS A 351 6730 13847 7379 1280 1752 745 C ATOM 276 CD LYS A 351 -27.979 -6.658 16.694 1.00 71.85 C ANISOU 276 CD LYS A 351 6577 13392 7331 1027 1854 933 C ATOM 277 CE LYS A 351 -29.398 -7.087 16.367 1.00 77.51 C ANISOU 277 CE LYS A 351 7136 14278 8035 896 1927 936 C ATOM 278 NZ LYS A 351 -29.418 -8.388 15.642 1.00 76.35 N ANISOU 278 NZ LYS A 351 7060 13909 8043 640 2033 1131 N ATOM 279 N PRO A 352 -27.821 -0.488 16.673 1.00 67.89 N ANISOU 279 N PRO A 352 6095 13152 6550 2000 1229 -160 N ATOM 280 CA PRO A 352 -28.280 0.733 15.994 1.00 66.44 C ANISOU 280 CA PRO A 352 5913 12953 6378 2143 1091 -425 C ATOM 281 C PRO A 352 -27.866 0.840 14.536 1.00 55.88 C ANISOU 281 C PRO A 352 4762 11223 5248 2075 1003 -494 C ATOM 282 O PRO A 352 -28.480 1.622 13.797 1.00 55.68 O ANISOU 282 O PRO A 352 4730 11174 5253 2141 901 -687 O ATOM 283 CB PRO A 352 -27.637 1.850 16.825 1.00 70.47 C ANISOU 283 CB PRO A 352 6453 13575 6747 2379 1004 -562 C ATOM 284 CG PRO A 352 -26.374 1.229 17.335 1.00 69.13 C ANISOU 284 CG PRO A 352 6404 13267 6598 2331 1048 -381 C ATOM 285 CD PRO A 352 -26.674 -0.233 17.561 1.00 69.96 C ANISOU 285 CD PRO A 352 6440 13412 6731 2113 1207 -120 C ATOM 286 N TYR A 353 -26.857 0.093 14.097 1.00 60.21 N ANISOU 286 N TYR A 353 5479 11459 5938 1945 1041 -348 N ATOM 287 CA TYR A 353 -26.355 0.188 12.727 1.00 53.94 C ANISOU 287 CA TYR A 353 4885 10270 5340 1874 969 -413 C ATOM 288 C TYR A 353 -27.199 -0.716 11.839 1.00 51.85 C ANISOU 288 C TYR A 353 4594 9918 5190 1655 1036 -322 C ATOM 289 O TYR A 353 -26.946 -1.918 11.737 1.00 55.09 O ANISOU 289 O TYR A 353 5041 10206 5687 1463 1156 -108 O ATOM 290 CB TYR A 353 -24.879 -0.186 12.670 1.00 50.81 C ANISOU 290 CB TYR A 353 4678 9575 5053 1837 987 -302 C ATOM 291 CG TYR A 353 -24.007 0.660 13.568 1.00 55.79 C ANISOU 291 CG TYR A 353 5334 10287 5574 2043 917 -380 C ATOM 292 CD1 TYR A 353 -23.526 1.891 13.141 1.00 52.87 C ANISOU 292 CD1 TYR A 353 5083 9787 5219 2206 775 -605 C ATOM 293 CD2 TYR A 353 -23.666 0.231 14.844 1.00 62.07 C ANISOU 293 CD2 TYR A 353 6045 11290 6248 2069 991 -228 C ATOM 294 CE1 TYR A 353 -22.730 2.670 13.959 1.00 56.38 C ANISOU 294 CE1 TYR A 353 5554 10306 5561 2388 709 -678 C ATOM 295 CE2 TYR A 353 -22.871 1.002 15.669 1.00 65.51 C ANISOU 295 CE2 TYR A 353 6510 11800 6580 2250 919 -297 C ATOM 296 CZ TYR A 353 -22.405 2.221 15.221 1.00 63.42 C ANISOU 296 CZ TYR A 353 6358 11406 6334 2409 779 -523 C ATOM 297 OH TYR A 353 -21.612 2.993 16.039 1.00 68.39 O ANISOU 297 OH TYR A 353 7019 12108 6858 2583 707 -594 O ATOM 298 N GLN A 354 -28.199 -0.133 11.183 1.00 44.30 N ANISOU 298 N GLN A 354 3617 7890 5325 478 1016 175 N ATOM 299 CA GLN A 354 -29.131 -0.875 10.346 1.00 48.09 C ANISOU 299 CA GLN A 354 4098 8380 5795 302 904 310 C ATOM 300 C GLN A 354 -28.778 -0.702 8.874 1.00 42.18 C ANISOU 300 C GLN A 354 3452 7415 5160 397 795 317 C ATOM 301 O GLN A 354 -28.411 0.393 8.437 1.00 39.67 O ANISOU 301 O GLN A 354 3059 7039 4977 608 835 213 O ATOM 302 CB GLN A 354 -30.568 -0.411 10.598 1.00 60.34 C ANISOU 302 CB GLN A 354 5347 10196 7382 235 971 328 C ATOM 303 CG GLN A 354 -31.625 -1.209 9.853 1.00 68.51 C ANISOU 303 CG GLN A 354 6366 11271 8394 34 862 473 C ATOM 304 CD GLN A 354 -33.034 -0.749 10.173 1.00 80.07 C ANISOU 304 CD GLN A 354 7528 13005 9892 -32 935 490 C ATOM 305 OE1 GLN A 354 -33.236 0.337 10.717 1.00 84.27 O ANISOU 305 OE1 GLN A 354 7846 13673 10498 104 1062 384 O ATOM 306 NE2 GLN A 354 -34.017 -1.578 9.841 1.00 85.82 N ANISOU 306 NE2 GLN A 354 8234 13809 10563 -243 856 624 N ATOM 307 N CYS A 355 -28.891 -1.790 8.115 1.00 46.15 N ANISOU 307 N CYS A 355 4127 7800 5607 237 658 442 N ATOM 308 CA CYS A 355 -28.641 -1.758 6.678 1.00 42.38 C ANISOU 308 CA CYS A 355 3756 7123 5226 296 545 464 C ATOM 309 C CYS A 355 -29.899 -1.289 5.957 1.00 49.39 C ANISOU 309 C CYS A 355 4417 8140 6210 265 529 505 C ATOM 310 O CYS A 355 -30.958 -1.914 6.074 1.00 52.73 O ANISOU 310 O CYS A 355 4757 8710 6568 68 502 611 O ATOM 311 CB CYS A 355 -28.215 -3.137 6.180 1.00 39.22 C ANISOU 311 CB CYS A 355 3641 6539 4723 134 407 578 C ATOM 312 SG CYS A 355 -27.976 -3.246 4.390 1.00 36.32 S ANISOU 312 SG CYS A 355 3415 5929 4457 172 259 620 S ATOM 313 N ASP A 356 -29.783 -0.192 5.207 1.00 46.44 N ANISOU 313 N ASP A 356 3942 7711 5991 458 544 424 N ATOM 314 CA ASP A 356 -30.918 0.410 4.522 1.00 53.77 C ANISOU 314 CA ASP A 356 4640 8760 7030 458 537 451 C ATOM 315 C ASP A 356 -31.021 -0.019 3.062 1.00 50.85 C ANISOU 315 C ASP A 356 4387 8228 6707 405 389 537 C ATOM 316 O ASP A 356 -31.656 0.677 2.263 1.00 54.83 O ANISOU 316 O ASP A 356 4730 8770 7333 466 374 536 O ATOM 317 CB ASP A 356 -30.845 1.935 4.623 1.00 58.77 C ANISOU 317 CB ASP A 356 5062 9456 7811 699 651 312 C ATOM 318 CG ASP A 356 -31.124 2.438 6.026 1.00 68.85 C ANISOU 318 CG ASP A 356 6155 10950 9053 726 805 238 C ATOM 319 OD1 ASP A 356 -31.971 1.835 6.717 1.00 75.84 O ANISOU 319 OD1 ASP A 356 6958 12017 9839 542 827 313 O ATOM 320 OD2 ASP A 356 -30.497 3.437 6.437 1.00 68.95 O ANISOU 320 OD2 ASP A 356 6116 10943 9138 924 903 104 O ATOM 321 N PHE A 357 -30.411 -1.142 2.695 1.00 56.52 N ANISOU 321 N PHE A 357 5380 8764 7331 294 280 610 N ATOM 322 CA PHE A 357 -30.612 -1.675 1.357 1.00 56.51 C ANISOU 322 CA PHE A 357 5489 8624 7356 210 138 703 C ATOM 323 C PHE A 357 -32.009 -2.279 1.235 1.00 62.23 C ANISOU 323 C PHE A 357 6087 9523 8033 -14 94 833 C ATOM 324 O PHE A 357 -32.650 -2.642 2.226 1.00 65.09 O ANISOU 324 O PHE A 357 6352 10076 8303 -143 153 871 O ATOM 325 CB PHE A 357 -29.549 -2.721 1.021 1.00 40.32 C ANISOU 325 CB PHE A 357 3772 6329 5220 152 38 742 C ATOM 326 CG PHE A 357 -28.266 -2.136 0.499 1.00 38.39 C ANISOU 326 CG PHE A 357 3669 5858 5060 369 29 638 C ATOM 327 N LYS A 358 -32.478 -2.385 -0.005 1.00 45.52 N ANISOU 327 N LYS A 358 3974 7341 5979 -62 -10 903 N ATOM 328 CA LYS A 358 -33.842 -2.829 -0.259 1.00 52.66 C ANISOU 328 CA LYS A 358 4740 8411 6858 -258 -55 1024 C ATOM 329 C LYS A 358 -34.041 -4.274 0.183 1.00 55.11 C ANISOU 329 C LYS A 358 5207 8735 6997 -507 -113 1140 C ATOM 330 O LYS A 358 -33.241 -5.154 -0.151 1.00 50.96 O ANISOU 330 O LYS A 358 4952 8009 6402 -566 -199 1177 O ATOM 331 CB LYS A 358 -34.177 -2.681 -1.743 1.00 53.56 C ANISOU 331 CB LYS A 358 4852 8426 7072 -256 -165 1074 C ATOM 332 N ASP A 359 -35.115 -4.508 0.941 1.00 59.26 N ANISOU 332 N ASP A 359 5559 9499 7458 -654 -63 1198 N ATOM 333 CA ASP A 359 -35.520 -5.847 1.378 1.00 65.04 C ANISOU 333 CA ASP A 359 6401 10280 8030 -907 -115 1319 C ATOM 334 C ASP A 359 -34.430 -6.535 2.197 1.00 61.33 C ANISOU 334 C ASP A 359 6163 9698 7444 -920 -100 1295 C ATOM 335 O ASP A 359 -34.224 -7.745 2.092 1.00 62.52 O ANISOU 335 O ASP A 359 6526 9747 7482 -1088 -188 1388 O ATOM 336 CB ASP A 359 -35.931 -6.721 0.190 1.00 68.17 C ANISOU 336 CB ASP A 359 6921 10575 8407 -1074 -265 1447 C ATOM 337 CG ASP A 359 -37.046 -6.104 -0.629 1.00 75.32 C ANISOU 337 CG ASP A 359 7599 11597 9422 -1077 -287 1483 C ATOM 338 OD1 ASP A 359 -38.216 -6.183 -0.198 1.00 83.39 O ANISOU 338 OD1 ASP A 359 8425 12845 10413 -1206 -254 1544 O ATOM 339 OD2 ASP A 359 -36.751 -5.528 -1.696 1.00 73.62 O ANISOU 339 OD2 ASP A 359 7400 11249 9325 -951 -336 1450 O ATOM 340 N CYS A 360 -33.725 -5.763 3.025 1.00 63.48 N ANISOU 340 N CYS A 360 6391 9985 7742 -742 14 1170 N ATOM 341 CA CYS A 360 -32.710 -6.323 3.915 1.00 58.09 C ANISOU 341 CA CYS A 360 5903 9217 6951 -744 41 1141 C ATOM 342 C CYS A 360 -33.082 -6.086 5.374 1.00 67.43 C ANISOU 342 C CYS A 360 6921 10632 8069 -766 173 1103 C ATOM 343 O CYS A 360 -33.412 -7.043 6.078 1.00 74.89 O ANISOU 343 O CYS A 360 7916 11662 8876 -958 164 1186 O ATOM 344 CB CYS A 360 -31.333 -5.742 3.593 1.00 49.66 C ANISOU 344 CB CYS A 360 4982 7928 5960 -518 48 1027 C ATOM 345 SG CYS A 360 -30.008 -6.407 4.628 1.00 46.59 S ANISOU 345 SG CYS A 360 4840 7418 5444 -510 76 991 S ATOM 346 N GLU A 361 -33.025 -4.842 5.852 1.00 44.06 N ANISOU 346 N GLU A 361 3767 7774 5201 -575 295 979 N ATOM 347 CA GLU A 361 -33.421 -4.464 7.210 1.00 53.69 C ANISOU 347 CA GLU A 361 4802 9224 6372 -579 432 929 C ATOM 348 C GLU A 361 -32.593 -5.165 8.285 1.00 51.35 C ANISOU 348 C GLU A 361 4682 8891 5936 -631 462 922 C ATOM 349 O GLU A 361 -33.030 -5.273 9.436 1.00 57.82 O ANISOU 349 O GLU A 361 5392 9906 6672 -715 548 923 O ATOM 350 CB GLU A 361 -34.915 -4.720 7.447 1.00 63.33 C ANISOU 350 CB GLU A 361 5814 10692 7557 -764 443 1021 C ATOM 351 N ARG A 362 -31.402 -5.645 7.942 1.00 58.95 N ANISOU 351 N ARG A 362 5915 9609 6873 -586 393 915 N ATOM 352 CA ARG A 362 -30.516 -6.229 8.937 1.00 58.71 C ANISOU 352 CA ARG A 362 6055 9530 6723 -614 422 901 C ATOM 353 C ARG A 362 -29.792 -5.133 9.708 1.00 53.11 C ANISOU 353 C ARG A 362 5262 8851 6066 -395 553 748 C ATOM 354 O ARG A 362 -29.551 -4.037 9.194 1.00 49.56 O ANISOU 354 O ARG A 362 4721 8355 5754 -193 589 649 O ATOM 355 CB ARG A 362 -29.501 -7.164 8.278 1.00 57.75 C ANISOU 355 CB ARG A 362 6253 9131 6557 -646 299 952 C ATOM 356 CG ARG A 362 -30.084 -8.491 7.825 1.00 66.94 C ANISOU 356 CG ARG A 362 7540 10268 7627 -896 177 1109 C ATOM 357 CD ARG A 362 -29.020 -9.362 7.182 1.00 64.99 C ANISOU 357 CD ARG A 362 7611 9738 7345 -914 63 1148 C ATOM 358 NE ARG A 362 -29.503 -10.712 6.906 1.00 72.64 N ANISOU 358 NE ARG A 362 8712 10680 8207 -1163 -45 1297 N ATOM 359 CZ ARG A 362 -29.371 -11.737 7.742 1.00 78.91 C ANISOU 359 CZ ARG A 362 9629 11496 8858 -1323 -54 1367 C ATOM 360 NH1 ARG A 362 -28.767 -11.569 8.911 1.00 78.99 N ANISOU 360 NH1 ARG A 362 9645 11556 8811 -1263 38 1303 N ATOM 361 NH2 ARG A 362 -29.841 -12.932 7.409 1.00 84.97 N ANISOU 361 NH2 ARG A 362 10513 12234 9538 -1546 -155 1502 N ATOM 362 N ARG A 363 -29.447 -5.437 10.957 1.00 53.95 N ANISOU 362 N ARG A 363 5402 9037 6059 -440 625 730 N ATOM 363 CA ARG A 363 -28.780 -4.473 11.818 1.00 51.76 C ANISOU 363 CA ARG A 363 5048 8805 5814 -254 755 590 C ATOM 364 C ARG A 363 -27.727 -5.175 12.662 1.00 48.24 C ANISOU 364 C ARG A 363 4818 8267 5243 -286 758 589 C ATOM 365 O ARG A 363 -27.783 -6.386 12.887 1.00 48.38 O ANISOU 365 O ARG A 363 4986 8263 5135 -481 688 701 O ATOM 366 CB ARG A 363 -29.776 -3.731 12.716 1.00 59.62 C ANISOU 366 CB ARG A 363 5742 10092 6819 -258 888 543 C ATOM 367 CG ARG A 363 -30.658 -4.630 13.560 1.00 68.52 C ANISOU 367 CG ARG A 363 6818 11413 7804 -502 897 647 C ATOM 368 CD ARG A 363 -31.541 -3.787 14.455 1.00 77.94 C ANISOU 368 CD ARG A 363 7712 12885 9018 -481 1039 583 C ATOM 369 NE ARG A 363 -32.305 -2.810 13.684 1.00 81.36 N ANISOU 369 NE ARG A 363 7926 13384 9604 -379 1060 545 N ATOM 370 CZ ARG A 363 -32.701 -1.632 14.154 1.00 87.85 C ANISOU 370 CZ ARG A 363 8497 14371 10511 -248 1191 438 C ATOM 371 NH1 ARG A 363 -32.396 -1.273 15.393 1.00 90.67 N ANISOU 371 NH1 ARG A 363 8790 14845 10814 -204 1316 353 N ATOM 372 NH2 ARG A 363 -33.393 -0.807 13.380 1.00 91.36 N ANISOU 372 NH2 ARG A 363 8753 14861 11097 -161 1198 415 N ATOM 373 N PHE A 364 -26.761 -4.388 13.131 1.00 50.99 N ANISOU 373 N PHE A 364 5180 8562 5630 -90 842 462 N ATOM 374 CA PHE A 364 -25.608 -4.912 13.843 1.00 50.49 C ANISOU 374 CA PHE A 364 5328 8387 5468 -84 846 447 C ATOM 375 C PHE A 364 -25.279 -4.002 15.017 1.00 51.84 C ANISOU 375 C PHE A 364 5365 8695 5638 46 999 320 C ATOM 376 O PHE A 364 -25.693 -2.842 15.068 1.00 51.72 O ANISOU 376 O PHE A 364 5125 8801 5725 180 1094 223 O ATOM 377 CB PHE A 364 -24.391 -5.042 12.916 1.00 43.59 C ANISOU 377 CB PHE A 364 4702 7212 4649 38 755 426 C ATOM 378 CG PHE A 364 -24.665 -5.831 11.668 1.00 43.55 C ANISOU 378 CG PHE A 364 4828 7060 4660 -70 608 537 C ATOM 379 CD1 PHE A 364 -25.150 -5.208 10.530 1.00 41.52 C ANISOU 379 CD1 PHE A 364 4469 6771 4535 9 572 523 C ATOM 380 CD2 PHE A 364 -24.444 -7.196 11.635 1.00 45.47 C ANISOU 380 CD2 PHE A 364 5295 7197 4786 -254 507 657 C ATOM 381 CE1 PHE A 364 -25.408 -5.933 9.383 1.00 43.14 C ANISOU 381 CE1 PHE A 364 4794 6844 4751 -96 437 625 C ATOM 382 CE2 PHE A 364 -24.698 -7.926 10.491 1.00 45.70 C ANISOU 382 CE2 PHE A 364 5446 7091 4829 -357 374 757 C ATOM 383 CZ PHE A 364 -25.182 -7.294 9.365 1.00 44.05 C ANISOU 383 CZ PHE A 364 5134 6855 4748 -280 340 740 C ATOM 384 N SER A 365 -24.517 -4.549 15.965 1.00 51.89 N ANISOU 384 N SER A 365 5513 8678 5526 3 1021 322 N ATOM 385 CA SER A 365 -24.106 -3.789 17.137 1.00 54.71 C ANISOU 385 CA SER A 365 5769 9154 5864 113 1162 206 C ATOM 386 C SER A 365 -22.891 -2.911 16.876 1.00 47.62 C ANISOU 386 C SER A 365 4947 8086 5062 364 1194 76 C ATOM 387 O SER A 365 -22.629 -1.991 17.658 1.00 46.07 O ANISOU 387 O SER A 365 4626 7990 4888 496 1320 -42 O ATOM 388 CB SER A 365 -23.808 -4.739 18.299 1.00 61.82 C ANISOU 388 CB SER A 365 6785 10110 6593 -45 1173 265 C ATOM 389 OG SER A 365 -23.252 -4.039 19.397 1.00 67.01 O ANISOU 389 OG SER A 365 7376 10857 7229 68 1301 152 O ATOM 390 N ARG A 366 -22.151 -3.166 15.800 1.00 54.10 N ANISOU 390 N ARG A 366 5966 8651 5938 432 1085 94 N ATOM 391 CA ARG A 366 -20.915 -2.455 15.514 1.00 49.09 C ANISOU 391 CA ARG A 366 5433 7833 5385 660 1102 -19 C ATOM 392 C ARG A 366 -20.943 -1.907 14.095 1.00 45.96 C ANISOU 392 C ARG A 366 5029 7293 5140 787 1037 -43 C ATOM 393 O ARG A 366 -21.554 -2.493 13.197 1.00 44.73 O ANISOU 393 O ARG A 366 4907 7091 4998 672 933 57 O ATOM 394 CB ARG A 366 -19.701 -3.371 15.695 1.00 44.62 C ANISOU 394 CB ARG A 366 5161 7067 4727 630 1034 19 C ATOM 395 CG ARG A 366 -19.493 -3.855 17.117 1.00 46.84 C ANISOU 395 CG ARG A 366 5466 7470 4861 527 1099 34 C ATOM 396 CD ARG A 366 -18.787 -5.199 17.138 1.00 44.36 C ANISOU 396 CD ARG A 366 5434 6987 4434 394 992 142 C ATOM 397 NE ARG A 366 -17.618 -5.222 16.263 1.00 36.99 N ANISOU 397 NE ARG A 366 4718 5771 3567 531 914 113 N ATOM 398 CZ ARG A 366 -16.761 -6.235 16.195 1.00 35.64 C ANISOU 398 CZ ARG A 366 4808 5411 3321 465 826 183 C ATOM 399 NH1 ARG A 366 -16.938 -7.307 16.956 1.00 42.07 N ANISOU 399 NH1 ARG A 366 5701 6290 3993 265 802 287 N ATOM 400 NH2 ARG A 366 -15.724 -6.177 15.370 1.00 29.75 N ANISOU 400 NH2 ARG A 366 4247 4413 2645 600 761 149 N ATOM 401 N SER A 367 -20.266 -0.773 13.903 1.00 49.35 N ANISOU 401 N SER A 367 5535 7712 5504 240 -61 -145 N ATOM 402 CA SER A 367 -20.236 -0.145 12.586 1.00 47.34 C ANISOU 402 CA SER A 367 5318 7364 5303 217 -85 -207 C ATOM 403 C SER A 367 -19.427 -0.971 11.594 1.00 43.06 C ANISOU 403 C SER A 367 4830 6689 4842 160 -53 -167 C ATOM 404 O SER A 367 -19.791 -1.064 10.415 1.00 38.30 O ANISOU 404 O SER A 367 4258 6013 4281 110 -43 -185 O ATOM 405 CB SER A 367 -19.668 1.270 12.692 1.00 49.77 C ANISOU 405 CB SER A 367 5630 7677 5604 278 -148 -289 C ATOM 406 OG SER A 367 -18.345 1.250 13.199 1.00 52.54 O ANISOU 406 OG SER A 367 5994 8000 5970 309 -160 -272 O ATOM 407 N ASP A 368 -18.327 -1.577 12.048 1.00 40.62 N ANISOU 407 N ASP A 368 4532 6346 4557 167 -35 -113 N ATOM 408 CA ASP A 368 -17.511 -2.381 11.143 1.00 40.52 C ANISOU 408 CA ASP A 368 4567 6202 4626 114 1 -75 C ATOM 409 C ASP A 368 -18.236 -3.649 10.712 1.00 40.64 C ANISOU 409 C ASP A 368 4585 6195 4662 42 65 -14 C ATOM 410 O ASP A 368 -17.977 -4.169 9.621 1.00 38.48 O ANISOU 410 O ASP A 368 4356 5811 4454 -15 95 -6 O ATOM 411 CB ASP A 368 -16.169 -2.721 11.797 1.00 41.13 C ANISOU 411 CB ASP A 368 4648 6250 4728 141 4 -29 C ATOM 412 CG ASP A 368 -16.321 -3.589 13.030 1.00 47.65 C ANISOU 412 CG ASP A 368 5432 7164 5509 152 33 52 C ATOM 413 OD1 ASP A 368 -17.417 -3.598 13.623 1.00 51.28 O ANISOU 413 OD1 ASP A 368 5852 7730 5902 161 38 56 O ATOM 414 OD2 ASP A 368 -15.339 -4.261 13.411 1.00 49.84 O ANISOU 414 OD2 ASP A 368 5713 7404 5820 153 52 115 O ATOM 415 N GLN A 369 -19.145 -4.159 11.548 1.00 36.57 N ANISOU 415 N GLN A 369 4022 5781 4093 44 88 28 N ATOM 416 CA GLN A 369 -19.964 -5.295 11.140 1.00 35.82 C ANISOU 416 CA GLN A 369 3922 5669 4018 -24 147 79 C ATOM 417 C GLN A 369 -20.935 -4.901 10.035 1.00 34.63 C ANISOU 417 C GLN A 369 3787 5496 3876 -63 134 20 C ATOM 418 O GLN A 369 -21.216 -5.699 9.133 1.00 33.95 O ANISOU 418 O GLN A 369 3725 5337 3836 -132 174 41 O ATOM 419 CB GLN A 369 -20.723 -5.857 12.342 1.00 39.30 C ANISOU 419 CB GLN A 369 4306 6228 4399 -8 175 136 C ATOM 420 CG GLN A 369 -19.839 -6.487 13.403 1.00 43.34 C ANISOU 420 CG GLN A 369 4802 6761 4903 20 195 212 C ATOM 421 CD GLN A 369 -20.630 -6.964 14.605 1.00 46.34 C ANISOU 421 CD GLN A 369 5127 7264 5215 39 222 267 C ATOM 422 OE1 GLN A 369 -21.705 -6.441 14.902 1.00 47.52 O ANISOU 422 OE1 GLN A 369 5245 7503 5308 56 208 230 O ATOM 423 NE2 GLN A 369 -20.105 -7.965 15.301 1.00 48.02 N ANISOU 423 NE2 GLN A 369 5328 7480 5437 37 264 358 N ATOM 424 N LEU A 370 -21.459 -3.675 10.089 1.00 36.60 N ANISOU 424 N LEU A 370 4020 5804 4081 -21 79 -53 N ATOM 425 CA LEU A 370 -22.361 -3.212 9.040 1.00 34.84 C ANISOU 425 CA LEU A 370 3809 5561 3866 -54 60 -108 C ATOM 426 C LEU A 370 -21.619 -3.005 7.727 1.00 34.58 C ANISOU 426 C LEU A 370 3843 5399 3896 -86 50 -142 C ATOM 427 O LEU A 370 -22.132 -3.352 6.657 1.00 32.60 O ANISOU 427 O LEU A 370 3619 5092 3674 -148 64 -150 O ATOM 428 CB LEU A 370 -23.055 -1.921 9.473 1.00 35.43 C ANISOU 428 CB LEU A 370 3847 5730 3885 5 4 -176 C ATOM 429 CG LEU A 370 -24.002 -1.303 8.441 1.00 36.75 C ANISOU 429 CG LEU A 370 4021 5883 4060 -21 -25 -234 C ATOM 430 CD1 LEU A 370 -25.128 -2.268 8.102 1.00 39.18 C ANISOU 430 CD1 LEU A 370 4311 6204 4374 -86 16 -196 C ATOM 431 CD2 LEU A 370 -24.557 0.023 8.938 1.00 36.48 C ANISOU 431 CD2 LEU A 370 3947 5937 3978 43 -78 -299 C ATOM 432 N LYS A 371 -20.409 -2.442 7.786 1.00 38.90 N ANISOU 432 N LYS A 371 4418 5899 4465 -47 25 -162 N ATOM 433 CA LYS A 371 -19.646 -2.210 6.564 1.00 39.64 C ANISOU 433 CA LYS A 371 4576 5868 4619 -75 20 -193 C ATOM 434 C LYS A 371 -19.212 -3.522 5.924 1.00 38.15 C ANISOU 434 C LYS A 371 4426 5580 4490 -146 83 -135 C ATOM 435 O LYS A 371 -19.212 -3.647 4.694 1.00 35.80 O ANISOU 435 O LYS A 371 4178 5191 4232 -199 95 -156 O ATOM 436 CB LYS A 371 -18.437 -1.322 6.855 1.00 42.84 C ANISOU 436 CB LYS A 371 4995 6245 5038 -14 -18 -226 C ATOM 437 CG LYS A 371 -18.802 0.117 7.181 1.00 46.12 C ANISOU 437 CG LYS A 371 5383 6733 5408 50 -83 -301 C ATOM 438 CD LYS A 371 -17.579 1.018 7.174 1.00 47.31 C ANISOU 438 CD LYS A 371 5557 6832 5589 100 -119 -342 C ATOM 439 CE LYS A 371 -17.971 2.474 7.369 1.00 50.28 C ANISOU 439 CE LYS A 371 5908 7268 5929 159 -180 -421 C ATOM 440 NZ LYS A 371 -16.793 3.383 7.314 1.00 51.81 N ANISOU 440 NZ LYS A 371 6123 7406 6158 206 -214 -466 N ATOM 441 N ARG A 372 -18.838 -4.513 6.739 1.00 34.64 N ANISOU 441 N ARG A 372 3959 5149 4053 -150 127 -62 N ATOM 442 CA ARG A 372 -18.520 -5.828 6.191 1.00 35.37 C ANISOU 442 CA ARG A 372 4081 5151 4206 -219 195 -3 C ATOM 443 C ARG A 372 -19.737 -6.445 5.515 1.00 36.46 C ANISOU 443 C ARG A 372 4218 5293 4341 -287 223 0 C ATOM 444 O ARG A 372 -19.621 -7.065 4.451 1.00 34.53 O ANISOU 444 O ARG A 372 4020 4950 4148 -354 259 3 O ATOM 445 CB ARG A 372 -17.996 -6.751 7.292 1.00 36.11 C ANISOU 445 CB ARG A 372 4142 5271 4306 -205 235 81 C ATOM 446 CG ARG A 372 -17.610 -8.136 6.790 1.00 38.05 C ANISOU 446 CG ARG A 372 4415 5419 4624 -274 310 146 C ATOM 447 CD ARG A 372 -17.061 -9.021 7.900 1.00 37.81 C ANISOU 447 CD ARG A 372 4348 5414 4603 -257 348 234 C ATOM 448 NE ARG A 372 -18.087 -9.394 8.869 1.00 42.22 N ANISOU 448 NE ARG A 372 4847 6093 5100 -245 359 274 N ATOM 449 CZ ARG A 372 -17.931 -10.334 9.795 1.00 43.87 C ANISOU 449 CZ ARG A 372 5021 6336 5311 -241 402 360 C ATOM 450 NH1 ARG A 372 -16.788 -11.004 9.878 1.00 42.93 N ANISOU 450 NH1 ARG A 372 4918 6139 5255 -247 435 417 N ATOM 451 NH2 ARG A 372 -18.918 -10.608 10.638 1.00 45.16 N ANISOU 451 NH2 ARG A 372 5132 6610 5416 -230 413 392 N ATOM 452 N HIS A 373 -20.917 -6.275 6.115 1.00 30.72 N ANISOU 452 N HIS A 373 3438 4679 3556 -271 207 -3 N ATOM 453 CA HIS A 373 -22.134 -6.832 5.535 1.00 30.95 C ANISOU 453 CA HIS A 373 3458 4720 3583 -333 229 -1 C ATOM 454 C HIS A 373 -22.504 -6.134 4.233 1.00 30.62 C ANISOU 454 C HIS A 373 3458 4626 3549 -363 192 -73 C ATOM 455 O HIS A 373 -22.873 -6.793 3.255 1.00 32.61 O ANISOU 455 O HIS A 373 3742 4816 3834 -436 220 -71 O ATOM 456 CB HIS A 373 -23.286 -6.728 6.531 1.00 31.58 C ANISOU 456 CB HIS A 373 3467 4933 3600 -304 220 10 C ATOM 457 CG HIS A 373 -24.640 -6.781 5.894 1.00 36.52 C ANISOU 457 CG HIS A 373 4077 5584 4216 -350 215 -15 C ATOM 458 ND1 HIS A 373 -25.231 -7.961 5.499 1.00 39.23 N ANISOU 458 ND1 HIS A 373 4417 5898 4590 -423 269 26 N ATOM 459 CD2 HIS A 373 -25.514 -5.797 5.576 1.00 37.84 C ANISOU 459 CD2 HIS A 373 4229 5799 4349 -334 162 -77 C ATOM 460 CE1 HIS A 373 -26.414 -7.703 4.969 1.00 41.90 C ANISOU 460 CE1 HIS A 373 4738 6269 4913 -450 246 -10 C ATOM 461 NE2 HIS A 373 -26.609 -6.397 5.004 1.00 43.36 N ANISOU 461 NE2 HIS A 373 4915 6500 5058 -397 181 -71 N ATOM 462 N GLN A 374 -22.417 -4.803 4.200 1.00 34.05 N ANISOU 462 N GLN A 374 3895 5087 3954 -308 128 -135 N ATOM 463 CA GLN A 374 -22.897 -4.053 3.045 1.00 34.90 C ANISOU 463 CA GLN A 374 4035 5162 4062 -329 87 -200 C ATOM 464 C GLN A 374 -22.044 -4.253 1.800 1.00 37.01 C ANISOU 464 C GLN A 374 4382 5295 4386 -377 104 -213 C ATOM 465 O GLN A 374 -22.446 -3.805 0.721 1.00 35.37 O ANISOU 465 O GLN A 374 4209 5052 4179 -407 77 -259 O ATOM 466 CB GLN A 374 -22.988 -2.565 3.390 1.00 33.52 C ANISOU 466 CB GLN A 374 3839 5049 3848 -254 19 -261 C ATOM 467 CG GLN A 374 -24.115 -2.244 4.363 1.00 35.14 C ANISOU 467 CG GLN A 374 3969 5386 3995 -217 -1 -263 C ATOM 468 CD GLN A 374 -24.312 -0.757 4.576 1.00 37.80 C ANISOU 468 CD GLN A 374 4285 5778 4299 -149 -66 -329 C ATOM 469 OE1 GLN A 374 -23.351 0.012 4.610 1.00 38.35 O ANISOU 469 OE1 GLN A 374 4378 5814 4379 -104 -93 -360 O ATOM 470 NE2 GLN A 374 -25.566 -0.343 4.718 1.00 39.04 N ANISOU 470 NE2 GLN A 374 4395 6018 4422 -142 -91 -352 N ATOM 471 N ARG A 375 -20.890 -4.916 1.911 1.00 37.91 N ANISOU 471 N ARG A 375 4524 5334 4545 -385 149 -174 N ATOM 472 CA ARG A 375 -20.118 -5.240 0.718 1.00 36.27 C ANISOU 472 CA ARG A 375 4392 4994 4394 -438 177 -183 C ATOM 473 C ARG A 375 -20.805 -6.289 -0.146 1.00 36.59 C ANISOU 473 C ARG A 375 4456 4992 4455 -529 221 -166 C ATOM 474 O ARG A 375 -20.531 -6.356 -1.349 1.00 37.01 O ANISOU 474 O ARG A 375 4575 4950 4539 -579 232 -193 O ATOM 475 CB ARG A 375 -18.714 -5.710 1.102 1.00 36.14 C ANISOU 475 CB ARG A 375 4394 4907 4429 -423 216 -141 C ATOM 476 CG ARG A 375 -17.788 -4.580 1.521 1.00 35.86 C ANISOU 476 CG ARG A 375 4360 4872 4391 -345 170 -174 C ATOM 477 CD ARG A 375 -16.360 -5.063 1.716 1.00 36.83 C ANISOU 477 CD ARG A 375 4508 4909 4577 -339 208 -135 C ATOM 478 NE ARG A 375 -15.447 -3.951 1.968 1.00 37.11 N ANISOU 478 NE ARG A 375 4548 4933 4619 -270 162 -173 N ATOM 479 CZ ARG A 375 -14.156 -4.089 2.248 1.00 37.08 C ANISOU 479 CZ ARG A 375 4557 4864 4667 -248 179 -149 C ATOM 480 NH1 ARG A 375 -13.616 -5.298 2.317 1.00 37.47 N ANISOU 480 NH1 ARG A 375 4615 4853 4768 -287 243 -83 N ATOM 481 NH2 ARG A 375 -13.404 -3.017 2.461 1.00 37.31 N ANISOU 481 NH2 ARG A 375 4588 4886 4701 -185 133 -190 N ATOM 482 N ARG A 376 -21.692 -7.105 0.431 1.00 36.90 N ANISOU 482 N ARG A 376 4444 5098 4478 -552 249 -124 N ATOM 483 CA ARG A 376 -22.461 -8.038 -0.384 1.00 41.82 C ANISOU 483 CA ARG A 376 5082 5687 5119 -639 285 -115 C ATOM 484 C ARG A 376 -23.507 -7.323 -1.227 1.00 42.87 C ANISOU 484 C ARG A 376 5223 5849 5216 -659 230 -175 C ATOM 485 O ARG A 376 -23.962 -7.880 -2.233 1.00 45.77 O ANISOU 485 O ARG A 376 5626 6167 5600 -734 248 -186 O ATOM 486 CB ARG A 376 -23.129 -9.098 0.496 1.00 46.94 C ANISOU 486 CB ARG A 376 5669 6399 5766 -656 332 -52 C ATOM 487 CG ARG A 376 -24.386 -8.629 1.211 1.00 49.78 C ANISOU 487 CG ARG A 376 5958 6889 6066 -623 292 -61 C ATOM 488 CD ARG A 376 -25.037 -9.767 1.981 1.00 54.63 C ANISOU 488 CD ARG A 376 6517 7555 6686 -648 347 4 C ATOM 489 NE ARG A 376 -25.419 -10.870 1.104 1.00 58.89 N ANISOU 489 NE ARG A 376 7080 8026 7270 -740 397 18 N ATOM 490 CZ ARG A 376 -26.589 -10.957 0.479 1.00 63.61 C ANISOU 490 CZ ARG A 376 7666 8645 7856 -789 381 -9 C ATOM 491 NH1 ARG A 376 -27.498 -10.005 0.634 1.00 64.06 N ANISOU 491 NH1 ARG A 376 7686 8790 7862 -753 319 -49 N ATOM 492 NH2 ARG A 376 -26.851 -11.997 -0.302 1.00 66.91 N ANISOU 492 NH2 ARG A 376 8108 8996 8318 -875 429 2 N ATOM 493 N HIS A 377 -23.897 -6.107 -0.842 1.00 33.45 N ANISOU 493 N HIS A 377 3998 4735 3976 -593 164 -214 N ATOM 494 CA HIS A 377 -24.798 -5.292 -1.647 1.00 37.14 C ANISOU 494 CA HIS A 377 4472 5226 4413 -604 106 -270 C ATOM 495 C HIS A 377 -24.047 -4.459 -2.678 1.00 34.85 C ANISOU 495 C HIS A 377 4254 4852 4135 -599 75 -320 C ATOM 496 O HIS A 377 -24.509 -4.315 -3.815 1.00 37.55 O ANISOU 496 O HIS A 377 4636 5158 4473 -648 54 -353 O ATOM 497 CB HIS A 377 -25.626 -4.364 -0.751 1.00 41.02 C ANISOU 497 CB HIS A 377 4892 5841 4853 -536 53 -288 C ATOM 498 CG HIS A 377 -26.470 -5.079 0.258 1.00 46.92 C ANISOU 498 CG HIS A 377 5567 6678 5583 -537 81 -243 C ATOM 499 ND1 HIS A 377 -27.397 -6.038 -0.089 1.00 51.32 N ANISOU 499 ND1 HIS A 377 6108 7239 6151 -607 112 -220 N ATOM 500 CD2 HIS A 377 -26.540 -4.959 1.605 1.00 48.12 C ANISOU 500 CD2 HIS A 377 5657 6919 5707 -476 85 -216 C ATOM 501 CE1 HIS A 377 -27.993 -6.486 1.001 1.00 52.77 C ANISOU 501 CE1 HIS A 377 6224 7509 6318 -588 136 -179 C ATOM 502 NE2 HIS A 377 -27.492 -5.847 2.043 1.00 51.42 N ANISOU 502 NE2 HIS A 377 6025 7392 6120 -509 121 -175 N ATOM 503 N THR A 378 -22.892 -3.908 -2.300 1.00 40.29 N ANISOU 503 N THR A 378 4960 5510 4839 -543 71 -324 N ATOM 504 CA THR A 378 -22.146 -3.015 -3.178 1.00 39.97 C ANISOU 504 CA THR A 378 4982 5393 4813 -528 41 -371 C ATOM 505 C THR A 378 -21.237 -3.754 -4.151 1.00 39.80 C ANISOU 505 C THR A 378 5041 5240 4843 -590 95 -361 C ATOM 506 O THR A 378 -20.783 -3.151 -5.129 1.00 39.89 O ANISOU 506 O THR A 378 5113 5179 4864 -597 78 -400 O ATOM 507 CB THR A 378 -21.306 -2.040 -2.349 1.00 39.69 C ANISOU 507 CB THR A 378 4926 5378 4775 -439 12 -386 C ATOM 508 OG1 THR A 378 -20.350 -2.773 -1.573 1.00 38.59 O ANISOU 508 OG1 THR A 378 4780 5214 4668 -427 61 -337 O ATOM 509 CG2 THR A 378 -22.196 -1.238 -1.413 1.00 40.57 C ANISOU 509 CG2 THR A 378 4962 5618 4835 -377 -39 -403 C ATOM 510 N GLY A 379 -20.959 -5.033 -3.908 1.00 36.35 N ANISOU 510 N GLY A 379 4603 4768 4439 -634 163 -310 N ATOM 511 CA GLY A 379 -20.081 -5.776 -4.790 1.00 36.70 C ANISOU 511 CA GLY A 379 4721 4686 4539 -694 221 -300 C ATOM 512 C GLY A 379 -18.621 -5.401 -4.692 1.00 35.21 C ANISOU 512 C GLY A 379 4566 4419 4393 -651 235 -300 C ATOM 513 O GLY A 379 -17.851 -5.704 -5.607 1.00 35.03 O ANISOU 513 O GLY A 379 4614 4283 4414 -693 273 -307 O ATOM 514 N VAL A 380 -18.215 -4.745 -3.609 1.00 36.32 N ANISOU 514 N VAL A 380 4659 4617 4523 -570 204 -294 N ATOM 515 CA VAL A 380 -16.817 -4.375 -3.413 1.00 37.25 C ANISOU 515 CA VAL A 380 4801 4667 4686 -525 213 -293 C ATOM 516 C VAL A 380 -16.040 -5.619 -2.999 1.00 36.72 C ANISOU 516 C VAL A 380 4733 4543 4675 -552 287 -228 C ATOM 517 O VAL A 380 -16.356 -6.253 -1.988 1.00 36.22 O ANISOU 517 O VAL A 380 4612 4550 4602 -542 303 -179 O ATOM 518 CB VAL A 380 -16.680 -3.262 -2.365 1.00 40.73 C ANISOU 518 CB VAL A 380 5187 5193 5095 -431 153 -311 C ATOM 519 CG1 VAL A 380 -15.213 -2.988 -2.072 1.00 41.69 C ANISOU 519 CG1 VAL A 380 5326 5246 5269 -387 163 -305 C ATOM 520 CG2 VAL A 380 -17.377 -1.996 -2.844 1.00 40.79 C ANISOU 520 CG2 VAL A 380 5197 5244 5058 -404 84 -375 C ATOM 521 N LYS A 381 -15.022 -5.969 -3.784 1.00 31.31 N ANISOU 521 N LYS A 381 4113 3731 4054 -586 333 -227 N ATOM 522 CA LYS A 381 -14.189 -7.147 -3.539 1.00 31.94 C ANISOU 522 CA LYS A 381 4198 3737 4201 -616 409 -167 C ATOM 523 C LYS A 381 -12.726 -6.744 -3.681 1.00 33.28 C ANISOU 523 C LYS A 381 4404 3808 4433 -583 420 -172 C ATOM 524 O LYS A 381 -12.114 -6.940 -4.738 1.00 34.07 O ANISOU 524 O LYS A 381 4574 3790 4583 -628 461 -189 O ATOM 525 CB LYS A 381 -14.545 -8.285 -4.497 1.00 33.51 C ANISOU 525 CB LYS A 381 4441 3863 4427 -713 474 -155 C ATOM 526 CG LYS A 381 -15.948 -8.847 -4.323 1.00 36.22 C ANISOU 526 CG LYS A 381 4743 4296 4722 -752 471 -143 C ATOM 527 CD LYS A 381 -16.260 -9.877 -5.400 1.00 43.32 C ANISOU 527 CD LYS A 381 5694 5116 5651 -851 531 -144 C ATOM 528 CE LYS A 381 -17.570 -10.598 -5.123 1.00 47.56 C ANISOU 528 CE LYS A 381 6182 5734 6154 -892 537 -123 C ATOM 529 NZ LYS A 381 -18.709 -9.653 -4.971 1.00 47.23 N ANISOU 529 NZ LYS A 381 6104 5806 6033 -859 457 -162 N ATOM 530 N PRO A 382 -12.133 -6.178 -2.624 1.00 37.85 N ANISOU 530 N PRO A 382 4937 4433 5012 -505 385 -160 N ATOM 531 CA PRO A 382 -10.750 -5.684 -2.738 1.00 38.32 C ANISOU 531 CA PRO A 382 5026 4402 5133 -469 388 -170 C ATOM 532 C PRO A 382 -9.689 -6.770 -2.749 1.00 40.07 C ANISOU 532 C PRO A 382 5264 4517 5443 -501 465 -113 C ATOM 533 O PRO A 382 -8.546 -6.482 -3.130 1.00 41.48 O ANISOU 533 O PRO A 382 5480 4595 5686 -488 481 -124 O ATOM 534 CB PRO A 382 -10.590 -4.788 -1.497 1.00 38.29 C ANISOU 534 CB PRO A 382 4957 4497 5094 -378 322 -175 C ATOM 535 CG PRO A 382 -11.981 -4.592 -0.952 1.00 37.99 C ANISOU 535 CG PRO A 382 4868 4598 4969 -367 280 -183 C ATOM 536 CD PRO A 382 -12.741 -5.818 -1.336 1.00 37.56 C ANISOU 536 CD PRO A 382 4821 4535 4913 -445 335 -147 C ATOM 537 N PHE A 383 -10.014 -7.994 -2.342 1.00 37.47 N ANISOU 537 N PHE A 383 4908 4204 5126 -541 516 -52 N ATOM 538 CA PHE A 383 -9.037 -9.069 -2.228 1.00 38.38 C ANISOU 538 CA PHE A 383 5028 4224 5329 -568 590 10 C ATOM 539 C PHE A 383 -9.126 -9.962 -3.459 1.00 40.76 C ANISOU 539 C PHE A 383 5395 4417 5676 -661 665 6 C ATOM 540 O PHE A 383 -10.196 -10.496 -3.765 1.00 44.11 O ANISOU 540 O PHE A 383 5819 4880 6061 -714 679 4 O ATOM 541 CB PHE A 383 -9.272 -9.877 -0.953 1.00 39.12 C ANISOU 541 CB PHE A 383 5049 4400 5415 -551 602 85 C ATOM 542 CG PHE A 383 -9.279 -9.043 0.295 1.00 39.29 C ANISOU 542 CG PHE A 383 5008 4540 5381 -464 528 87 C ATOM 543 CD1 PHE A 383 -8.100 -8.767 0.967 1.00 41.58 C ANISOU 543 CD1 PHE A 383 5278 4805 5714 -408 514 111 C ATOM 544 CD2 PHE A 383 -10.465 -8.529 0.794 1.00 38.12 C ANISOU 544 CD2 PHE A 383 4820 4526 5139 -439 474 64 C ATOM 545 CE1 PHE A 383 -8.104 -7.998 2.116 1.00 40.57 C ANISOU 545 CE1 PHE A 383 5095 4788 5532 -330 445 108 C ATOM 546 CE2 PHE A 383 -10.476 -7.761 1.943 1.00 37.66 C ANISOU 546 CE2 PHE A 383 4706 4575 5027 -360 410 62 C ATOM 547 CZ PHE A 383 -9.294 -7.495 2.605 1.00 39.38 C ANISOU 547 CZ PHE A 383 4908 4771 5285 -306 395 82 C ATOM 548 N GLN A 384 -8.004 -10.125 -4.157 1.00 38.05 N ANISOU 548 N GLN A 384 4385 5045 5026 153 746 127 N ATOM 549 CA GLN A 384 -7.959 -10.877 -5.402 1.00 40.36 C ANISOU 549 CA GLN A 384 4676 5439 5219 207 811 26 C ATOM 550 C GLN A 384 -6.928 -11.993 -5.308 1.00 41.30 C ANISOU 550 C GLN A 384 4754 5494 5444 251 814 -78 C ATOM 551 O GLN A 384 -5.805 -11.778 -4.838 1.00 42.38 O ANISOU 551 O GLN A 384 4824 5568 5709 261 833 -47 O ATOM 552 CB GLN A 384 -7.634 -9.961 -6.586 1.00 44.83 C ANISOU 552 CB GLN A 384 5200 6147 5688 233 933 89 C ATOM 553 CG GLN A 384 -7.777 -10.631 -7.941 1.00 48.98 C ANISOU 553 CG GLN A 384 5735 6791 6085 287 1000 -8 C ATOM 554 CD GLN A 384 -7.585 -9.664 -9.092 1.00 54.95 C ANISOU 554 CD GLN A 384 6461 7687 6730 309 1117 61 C ATOM 555 OE1 GLN A 384 -6.814 -8.709 -8.995 1.00 58.70 O ANISOU 555 OE1 GLN A 384 6877 8165 7260 303 1175 159 O ATOM 556 NE2 GLN A 384 -8.294 -9.903 -10.189 1.00 56.66 N ANISOU 556 NE2 GLN A 384 6720 8019 6789 336 1151 11 N ATOM 557 N CYS A 385 -7.316 -13.182 -5.762 1.00 40.24 N ANISOU 557 N CYS A 385 4660 5375 5256 280 793 -204 N ATOM 558 CA CYS A 385 -6.418 -14.329 -5.744 1.00 43.07 C ANISOU 558 CA CYS A 385 4985 5677 5702 326 793 -314 C ATOM 559 C CYS A 385 -5.293 -14.135 -6.753 1.00 50.54 C ANISOU 559 C CYS A 385 5849 6712 6641 381 915 -320 C ATOM 560 O CYS A 385 -5.539 -13.823 -7.921 1.00 54.84 O ANISOU 560 O CYS A 385 6392 7390 7052 405 996 -317 O ATOM 561 CB CYS A 385 -7.194 -15.610 -6.051 1.00 42.01 C ANISOU 561 CB CYS A 385 4916 5545 5500 341 743 -446 C ATOM 562 SG CYS A 385 -6.195 -17.119 -6.080 1.00 46.12 S ANISOU 562 SG CYS A 385 5406 5999 6118 400 736 -593 S ATOM 563 N LYS A 386 -4.053 -14.321 -6.299 1.00 43.60 N ANISOU 563 N LYS A 386 4901 5758 5906 403 927 -330 N ATOM 564 CA LYS A 386 -2.903 -14.162 -7.181 1.00 51.50 C ANISOU 564 CA LYS A 386 5818 6833 6917 454 1044 -339 C ATOM 565 C LYS A 386 -2.762 -15.302 -8.180 1.00 55.73 C ANISOU 565 C LYS A 386 6355 7432 7386 514 1084 -474 C ATOM 566 O LYS A 386 -1.929 -15.204 -9.088 1.00 63.03 O ANISOU 566 O LYS A 386 7217 8439 8293 560 1189 -489 O ATOM 567 CB LYS A 386 -1.622 -14.039 -6.354 1.00 53.06 C ANISOU 567 CB LYS A 386 5938 6925 7295 459 1040 -314 C ATOM 568 N THR A 387 -3.549 -16.368 -8.043 1.00 53.85 N ANISOU 568 N THR A 387 6188 7161 7114 514 1004 -573 N ATOM 569 CA THR A 387 -3.462 -17.529 -8.922 1.00 59.08 C ANISOU 569 CA THR A 387 6855 7873 7718 570 1031 -709 C ATOM 570 C THR A 387 -4.520 -17.519 -10.019 1.00 59.86 C ANISOU 570 C THR A 387 7010 8104 7630 579 1063 -733 C ATOM 571 O THR A 387 -4.195 -17.732 -11.191 1.00 65.24 O ANISOU 571 O THR A 387 7666 8893 8228 631 1152 -783 O ATOM 572 CB THR A 387 -3.575 -18.819 -8.099 1.00 58.01 C ANISOU 572 CB THR A 387 6760 7611 7671 570 923 -815 C ATOM 573 OG1 THR A 387 -2.495 -18.885 -7.159 1.00 59.72 O ANISOU 573 OG1 THR A 387 6922 7708 8061 572 896 -803 O ATOM 574 CG2 THR A 387 -3.524 -20.040 -9.006 1.00 63.12 C ANISOU 574 CG2 THR A 387 7417 8310 8258 628 946 -958 C ATOM 575 N CYS A 388 -5.783 -17.272 -9.667 1.00 59.02 N ANISOU 575 N CYS A 388 6980 7991 7455 530 993 -698 N ATOM 576 CA CYS A 388 -6.874 -17.306 -10.632 1.00 59.87 C ANISOU 576 CA CYS A 388 7145 8215 7388 537 1010 -727 C ATOM 577 C CYS A 388 -7.603 -15.978 -10.778 1.00 58.19 C ANISOU 577 C CYS A 388 6954 8073 7083 497 1031 -601 C ATOM 578 O CYS A 388 -8.592 -15.913 -11.519 1.00 58.25 O ANISOU 578 O CYS A 388 7014 8175 6944 499 1037 -616 O ATOM 579 CB CYS A 388 -7.884 -18.399 -10.255 1.00 55.69 C ANISOU 579 CB CYS A 388 6695 7627 6839 522 905 -827 C ATOM 580 SG CYS A 388 -8.823 -18.058 -8.751 1.00 45.52 S ANISOU 580 SG CYS A 388 5468 6211 5616 438 778 -756 S ATOM 581 N GLN A 389 -7.157 -14.926 -10.088 1.00 53.86 N ANISOU 581 N GLN A 389 6368 7481 6616 462 1039 -479 N ATOM 582 CA GLN A 389 -7.708 -13.574 -10.201 1.00 53.24 C ANISOU 582 CA GLN A 389 6301 7466 6461 425 1065 -349 C ATOM 583 C GLN A 389 -9.157 -13.476 -9.730 1.00 47.22 C ANISOU 583 C GLN A 389 5624 6685 5633 373 971 -333 C ATOM 584 O GLN A 389 -9.851 -12.508 -10.055 1.00 47.26 O ANISOU 584 O GLN A 389 5653 6765 5538 350 990 -249 O ATOM 585 CB GLN A 389 -7.581 -13.035 -11.631 1.00 61.50 C ANISOU 585 CB GLN A 389 7328 8671 7370 466 1185 -330 C ATOM 586 CG GLN A 389 -6.259 -12.336 -11.915 1.00 69.77 C ANISOU 586 CG GLN A 389 8286 9744 8479 490 1291 -264 C ATOM 587 CD GLN A 389 -5.059 -13.230 -11.673 1.00 74.64 C ANISOU 587 CD GLN A 389 8841 10288 9229 527 1302 -346 C ATOM 588 OE1 GLN A 389 -5.010 -14.365 -12.147 1.00 76.41 O ANISOU 588 OE1 GLN A 389 9077 10526 9430 569 1299 -470 O ATOM 589 NE2 GLN A 389 -4.086 -12.724 -10.925 1.00 76.50 N ANISOU 589 NE2 GLN A 389 9012 10447 9609 512 1311 -279 N ATOM 590 N ARG A 390 -9.638 -14.446 -8.959 1.00 52.84 N ANISOU 590 N ARG A 390 6382 7296 6399 354 869 -411 N ATOM 591 CA ARG A 390 -10.967 -14.341 -8.375 1.00 48.52 C ANISOU 591 CA ARG A 390 5911 6716 5808 300 777 -393 C ATOM 592 C ARG A 390 -10.942 -13.363 -7.207 1.00 42.60 C ANISOU 592 C ARG A 390 5153 5880 5152 241 733 -268 C ATOM 593 O ARG A 390 -9.987 -13.332 -6.424 1.00 43.19 O ANISOU 593 O ARG A 390 5183 5860 5369 238 723 -241 O ATOM 594 CB ARG A 390 -11.472 -15.710 -7.914 1.00 47.78 C ANISOU 594 CB ARG A 390 5870 6539 5747 296 687 -517 C ATOM 595 CG ARG A 390 -12.861 -15.666 -7.296 1.00 46.31 C ANISOU 595 CG ARG A 390 5762 6315 5519 238 592 -505 C ATOM 596 CD ARG A 390 -13.528 -17.031 -7.278 1.00 49.40 C ANISOU 596 CD ARG A 390 6210 6667 5892 244 525 -642 C ATOM 597 NE ARG A 390 -14.880 -16.957 -6.730 1.00 47.55 N ANISOU 597 NE ARG A 390 6049 6402 5615 187 441 -631 N ATOM 598 CZ ARG A 390 -15.755 -17.957 -6.752 1.00 49.07 C ANISOU 598 CZ ARG A 390 6300 6575 5768 181 380 -736 C ATOM 599 NH1 ARG A 390 -15.425 -19.118 -7.300 1.00 51.51 N ANISOU 599 NH1 ARG A 390 6607 6892 6074 229 392 -861 N ATOM 600 NH2 ARG A 390 -16.963 -17.795 -6.228 1.00 47.06 N ANISOU 600 NH2 ARG A 390 6107 6293 5480 126 308 -718 N ATOM 601 N LYS A 391 -11.996 -12.560 -7.095 1.00 44.89 N ANISOU 601 N LYS A 391 5489 6204 5362 198 704 -194 N ATOM 602 CA LYS A 391 -12.068 -11.492 -6.110 1.00 40.20 C ANISOU 602 CA LYS A 391 4892 5548 4836 143 668 -67 C ATOM 603 C LYS A 391 -12.958 -11.885 -4.936 1.00 35.81 C ANISOU 603 C LYS A 391 4400 4878 4330 88 547 -81 C ATOM 604 O LYS A 391 -13.888 -12.684 -5.074 1.00 33.61 O ANISOU 604 O LYS A 391 4181 4602 3987 83 497 -168 O ATOM 605 CB LYS A 391 -12.589 -10.204 -6.749 1.00 42.81 C ANISOU 605 CB LYS A 391 5226 5993 5047 130 721 38 C ATOM 606 CG LYS A 391 -11.720 -9.673 -7.877 1.00 50.67 C ANISOU 606 CG LYS A 391 6161 7101 5991 179 846 68 C ATOM 607 CD LYS A 391 -12.315 -8.407 -8.472 1.00 53.80 C ANISOU 607 CD LYS A 391 6571 7605 6264 164 892 173 C ATOM 608 CE LYS A 391 -11.457 -7.868 -9.604 1.00 62.37 C ANISOU 608 CE LYS A 391 7600 8801 7295 212 1020 206 C ATOM 609 NZ LYS A 391 -12.048 -6.641 -10.207 1.00 65.57 N ANISOU 609 NZ LYS A 391 8026 9312 7576 199 1064 307 N ATOM 610 N PHE A 392 -12.661 -11.308 -3.771 1.00 35.92 N ANISOU 610 N PHE A 392 4400 4787 4460 47 502 5 N ATOM 611 CA PHE A 392 -13.414 -11.565 -2.552 1.00 32.21 C ANISOU 611 CA PHE A 392 3988 4200 4049 -7 391 6 C ATOM 612 C PHE A 392 -13.502 -10.286 -1.733 1.00 30.54 C ANISOU 612 C PHE A 392 3769 3952 3883 -57 369 147 C ATOM 613 O PHE A 392 -12.625 -9.422 -1.806 1.00 34.23 O ANISOU 613 O PHE A 392 4174 4438 4394 -47 428 232 O ATOM 614 CB PHE A 392 -12.773 -12.681 -1.714 1.00 33.75 C ANISOU 614 CB PHE A 392 4182 4260 4382 1 334 -74 C ATOM 615 CG PHE A 392 -12.708 -14.003 -2.420 1.00 37.39 C ANISOU 615 CG PHE A 392 4654 4745 4807 48 346 -217 C ATOM 616 CD1 PHE A 392 -13.763 -14.896 -2.342 1.00 35.33 C ANISOU 616 CD1 PHE A 392 4466 4463 4494 31 279 -305 C ATOM 617 CD2 PHE A 392 -11.595 -14.351 -3.168 1.00 41.38 C ANISOU 617 CD2 PHE A 392 5097 5294 5332 108 423 -263 C ATOM 618 CE1 PHE A 392 -13.709 -16.112 -2.993 1.00 38.55 C ANISOU 618 CE1 PHE A 392 4885 4893 4871 74 288 -438 C ATOM 619 CE2 PHE A 392 -11.535 -15.565 -3.823 1.00 43.58 C ANISOU 619 CE2 PHE A 392 5386 5595 5577 153 433 -395 C ATOM 620 CZ PHE A 392 -12.595 -16.446 -3.736 1.00 42.25 C ANISOU 620 CZ PHE A 392 5291 5405 5357 136 364 -483 C ATOM 621 N SER A 393 -14.573 -10.176 -0.946 1.00 33.00 N ANISOU 621 N SER A 393 4144 4209 4186 -112 284 168 N ATOM 622 CA SER A 393 -14.812 -8.995 -0.128 1.00 32.15 C ANISOU 622 CA SER A 393 4038 4064 4114 -162 253 297 C ATOM 623 C SER A 393 -14.116 -9.048 1.225 1.00 30.70 C ANISOU 623 C SER A 393 3840 3730 4097 -184 194 331 C ATOM 624 O SER A 393 -14.097 -8.034 1.931 1.00 30.02 O ANISOU 624 O SER A 393 3743 3606 4057 -220 174 442 O ATOM 625 CB SER A 393 -16.317 -8.799 0.095 1.00 31.34 C ANISOU 625 CB SER A 393 4010 3976 3923 -211 189 308 C ATOM 626 OG SER A 393 -16.828 -9.778 0.983 1.00 30.23 O ANISOU 626 OG SER A 393 3926 3722 3838 -239 98 235 O ATOM 627 N ARG A 394 -13.551 -10.194 1.601 1.00 33.36 N ANISOU 627 N ARG A 394 4175 3977 4522 -162 163 237 N ATOM 628 CA ARG A 394 -12.940 -10.361 2.910 1.00 33.74 C ANISOU 628 CA ARG A 394 4219 3875 4727 -180 98 257 C ATOM 629 C ARG A 394 -11.600 -11.065 2.764 1.00 37.63 C ANISOU 629 C ARG A 394 4653 4330 5314 -126 133 194 C ATOM 630 O ARG A 394 -11.405 -11.884 1.863 1.00 41.43 O ANISOU 630 O ARG A 394 5125 4871 5746 -81 177 96 O ATOM 631 CB ARG A 394 -13.859 -11.151 3.855 1.00 29.98 C ANISOU 631 CB ARG A 394 3826 3292 4273 -220 -8 203 C ATOM 632 CG ARG A 394 -15.085 -10.375 4.312 1.00 29.58 C ANISOU 632 CG ARG A 394 3829 3249 4162 -281 -55 279 C ATOM 633 CD ARG A 394 -16.157 -11.289 4.889 1.00 28.19 C ANISOU 633 CD ARG A 394 3738 3001 3970 -316 -141 203 C ATOM 634 NE ARG A 394 -15.629 -12.204 5.896 1.00 28.46 N ANISOU 634 NE ARG A 394 3791 2888 4135 -316 -205 150 N ATOM 635 CZ ARG A 394 -16.386 -12.932 6.712 1.00 25.87 C ANISOU 635 CZ ARG A 394 3537 2463 3829 -352 -288 101 C ATOM 636 NH1 ARG A 394 -17.708 -12.847 6.646 1.00 24.58 N ANISOU 636 NH1 ARG A 394 3432 2336 3571 -393 -317 96 N ATOM 637 NH2 ARG A 394 -15.822 -13.742 7.598 1.00 26.72 N ANISOU 637 NH2 ARG A 394 3661 2437 4055 -347 -342 55 N ATOM 638 N SER A 395 -10.673 -10.730 3.665 1.00 33.99 N ANISOU 638 N SER A 395 3724 4477 4712 -736 316 -1123 N ATOM 639 CA SER A 395 -9.346 -11.333 3.617 1.00 31.58 C ANISOU 639 CA SER A 395 3511 4326 4162 -635 334 -952 C ATOM 640 C SER A 395 -9.396 -12.814 3.973 1.00 35.93 C ANISOU 640 C SER A 395 4053 4755 4844 -597 406 -847 C ATOM 641 O SER A 395 -8.667 -13.623 3.388 1.00 36.47 O ANISOU 641 O SER A 395 4202 4819 4834 -464 341 -780 O ATOM 642 CB SER A 395 -8.396 -10.588 4.554 1.00 29.97 C ANISOU 642 CB SER A 395 3313 4419 3654 -711 471 -803 C ATOM 643 OG SER A 395 -8.846 -10.663 5.896 1.00 36.37 O ANISOU 643 OG SER A 395 4028 5255 4537 -856 660 -726 O ATOM 644 N ASP A 396 -10.250 -13.190 4.928 1.00 32.55 N ANISOU 644 N ASP A 396 3527 4227 4615 -714 540 -833 N ATOM 645 CA ASP A 396 -10.334 -14.592 5.321 1.00 35.54 C ANISOU 645 CA ASP A 396 3896 4487 5123 -687 616 -733 C ATOM 646 C ASP A 396 -11.038 -15.431 4.261 1.00 39.16 C ANISOU 646 C ASP A 396 4369 4670 5842 -583 468 -863 C ATOM 647 O ASP A 396 -10.769 -16.632 4.146 1.00 42.43 O ANISOU 647 O ASP A 396 4818 5001 6303 -500 473 -782 O ATOM 648 CB ASP A 396 -11.036 -14.717 6.675 1.00 39.85 C ANISOU 648 CB ASP A 396 4333 5011 5798 -847 807 -679 C ATOM 649 CG ASP A 396 -12.449 -14.173 6.656 1.00 44.15 C ANISOU 649 CG ASP A 396 4781 5379 6615 -949 782 -866 C ATOM 650 OD1 ASP A 396 -12.682 -13.150 5.980 1.00 41.25 O ANISOU 650 OD1 ASP A 396 4421 5022 6231 -945 665 -1007 O ATOM 651 OD2 ASP A 396 -13.331 -14.775 7.306 1.00 51.07 O ANISOU 651 OD2 ASP A 396 5577 6106 7723 -1031 877 -874 O ATOM 652 N HIS A 397 -11.931 -14.822 3.477 1.00 34.13 N ANISOU 652 N HIS A 397 3706 3888 5375 -586 337 -1066 N ATOM 653 CA HIS A 397 -12.516 -15.533 2.344 1.00 35.55 C ANISOU 653 CA HIS A 397 3908 3819 5780 -475 178 -1198 C ATOM 654 C HIS A 397 -11.466 -15.823 1.280 1.00 31.86 C ANISOU 654 C HIS A 397 3562 3412 5131 -305 39 -1164 C ATOM 655 O HIS A 397 -11.481 -16.893 0.658 1.00 34.35 O ANISOU 655 O HIS A 397 3915 3575 5561 -195 -34 -1167 O ATOM 656 CB HIS A 397 -13.672 -14.727 1.751 1.00 35.63 C ANISOU 656 CB HIS A 397 3865 3678 5996 -517 67 -1424 C ATOM 657 CG HIS A 397 -14.916 -14.748 2.582 1.00 41.09 C ANISOU 657 CG HIS A 397 4434 4232 6946 -661 175 -1488 C ATOM 658 ND1 HIS A 397 -16.055 -14.055 2.232 1.00 43.40 N ANISOU 658 ND1 HIS A 397 4663 4384 7444 -718 100 -1686 N ATOM 659 CD2 HIS A 397 -15.203 -15.382 3.744 1.00 46.76 C ANISOU 659 CD2 HIS A 397 5084 4931 7752 -759 352 -1381 C ATOM 660 CE1 HIS A 397 -16.989 -14.259 3.144 1.00 48.20 C ANISOU 660 CE1 HIS A 397 5166 4894 8255 -847 226 -1701 C ATOM 661 NE2 HIS A 397 -16.498 -15.060 4.072 1.00 50.64 N ANISOU 661 NE2 HIS A 397 5471 5274 8498 -875 382 -1518 N ATOM 662 N LEU A 398 -10.545 -14.883 1.058 1.00 39.21 N ANISOU 662 N LEU A 398 4556 4565 5779 -281 3 -1132 N ATOM 663 CA LEU A 398 -9.487 -15.101 0.077 1.00 39.26 C ANISOU 663 CA LEU A 398 4678 4646 5593 -124 -124 -1095 C ATOM 664 C LEU A 398 -8.527 -16.193 0.530 1.00 42.58 C ANISOU 664 C LEU A 398 5146 5152 5881 -63 -33 -894 C ATOM 665 O LEU A 398 -8.149 -17.062 -0.264 1.00 43.47 O ANISOU 665 O LEU A 398 5327 5183 6008 74 -132 -882 O ATOM 666 CB LEU A 398 -8.730 -13.798 -0.178 1.00 34.40 C ANISOU 666 CB LEU A 398 4114 4257 4698 -126 -171 -1105 C ATOM 667 CG LEU A 398 -7.496 -13.922 -1.074 1.00 35.10 C ANISOU 667 CG LEU A 398 4326 4466 4544 25 -284 -1049 C ATOM 668 CD1 LEU A 398 -7.891 -14.426 -2.451 1.00 35.23 C ANISOU 668 CD1 LEU A 398 4390 4266 4731 158 -480 -1191 C ATOM 669 CD2 LEU A 398 -6.756 -12.596 -1.172 1.00 32.39 C ANISOU 669 CD2 LEU A 398 4027 4360 3919 4 -306 -1048 C ATOM 670 N LYS A 399 -8.124 -16.165 1.804 1.00 39.45 N ANISOU 670 N LYS A 399 4714 4920 5356 -162 153 -735 N ATOM 671 CA LYS A 399 -7.182 -17.160 2.307 1.00 40.34 C ANISOU 671 CA LYS A 399 4871 5128 5330 -108 248 -537 C ATOM 672 C LYS A 399 -7.766 -18.564 2.230 1.00 44.58 C ANISOU 672 C LYS A 399 5390 5427 6123 -62 251 -533 C ATOM 673 O LYS A 399 -7.055 -19.523 1.907 1.00 46.75 O ANISOU 673 O LYS A 399 5734 5700 6331 55 223 -438 O ATOM 674 CB LYS A 399 -6.781 -16.822 3.743 1.00 41.13 C ANISOU 674 CB LYS A 399 4925 5435 5269 -236 453 -380 C ATOM 675 N THR A 400 -9.060 -18.706 2.523 1.00 32.97 N ANISOU 675 N THR A 400 3826 3754 4947 -152 284 -638 N ATOM 676 CA THR A 400 -9.700 -20.014 2.427 1.00 38.58 C ANISOU 676 CA THR A 400 4515 4226 5918 -114 285 -648 C ATOM 677 C THR A 400 -9.771 -20.488 0.980 1.00 39.72 C ANISOU 677 C THR A 400 4725 4205 6162 41 83 -765 C ATOM 678 O THR A 400 -9.603 -21.681 0.702 1.00 42.27 O ANISOU 678 O THR A 400 5084 4417 6560 135 62 -711 O ATOM 679 CB THR A 400 -11.097 -19.960 3.047 1.00 42.45 C ANISOU 679 CB THR A 400 4888 4542 6699 -252 363 -746 C ATOM 680 OG1 THR A 400 -11.004 -19.494 4.399 1.00 43.38 O ANISOU 680 OG1 THR A 400 4946 4821 6715 -397 551 -635 O ATOM 681 CG2 THR A 400 -11.742 -21.339 3.038 1.00 50.18 C ANISOU 681 CG2 THR A 400 5843 5280 7942 -221 379 -747 C ATOM 682 N HIS A 401 -10.007 -19.564 0.044 1.00 39.63 N ANISOU 682 N HIS A 401 4731 4176 6150 70 -68 -925 N ATOM 683 CA HIS A 401 -10.089 -19.939 -1.365 1.00 44.08 C ANISOU 683 CA HIS A 401 5357 4586 6806 216 -266 -1045 C ATOM 684 C HIS A 401 -8.752 -20.444 -1.889 1.00 40.44 C ANISOU 684 C HIS A 401 5009 4254 6104 361 -323 -923 C ATOM 685 O HIS A 401 -8.712 -21.358 -2.722 1.00 42.98 O ANISOU 685 O HIS A 401 5378 4431 6522 485 -428 -950 O ATOM 686 CB HIS A 401 -10.566 -18.752 -2.199 1.00 47.18 C ANISOU 686 CB HIS A 401 5747 4955 7224 212 -409 -1235 C ATOM 687 CG HIS A 401 -10.251 -18.877 -3.658 1.00 52.07 C ANISOU 687 CG HIS A 401 6456 5505 7824 371 -614 -1329 C ATOM 688 ND1 HIS A 401 -10.972 -19.687 -4.508 1.00 53.40 N ANISOU 688 ND1 HIS A 401 6623 5417 8250 453 -731 -1446 N ATOM 689 CD2 HIS A 401 -9.287 -18.301 -4.414 1.00 52.96 C ANISOU 689 CD2 HIS A 401 6661 5771 7689 462 -722 -1324 C ATOM 690 CE1 HIS A 401 -10.469 -19.601 -5.727 1.00 53.52 C ANISOU 690 CE1 HIS A 401 6726 5431 8178 588 -903 -1508 C ATOM 691 NE2 HIS A 401 -9.445 -18.767 -5.697 1.00 52.24 N ANISOU 691 NE2 HIS A 401 6623 5515 7710 596 -901 -1436 N ATOM 692 N THR A 402 -7.646 -19.862 -1.419 1.00 48.70 N ANISOU 692 N THR A 402 6098 5570 6837 347 -254 -791 N ATOM 693 CA THR A 402 -6.332 -20.247 -1.922 1.00 48.41 C ANISOU 693 CA THR A 402 6168 5672 6553 482 -310 -680 C ATOM 694 C THR A 402 -5.982 -21.692 -1.591 1.00 55.29 C ANISOU 694 C THR A 402 7060 6485 7465 543 -241 -539 C ATOM 695 O THR A 402 -5.070 -22.253 -2.208 1.00 55.91 O ANISOU 695 O THR A 402 7226 6612 7406 677 -315 -473 O ATOM 696 CB THR A 402 -5.255 -19.312 -1.368 1.00 45.02 C ANISOU 696 CB THR A 402 5772 5551 5784 440 -233 -565 C ATOM 697 OG1 THR A 402 -5.303 -19.319 0.064 1.00 50.16 O ANISOU 697 OG1 THR A 402 6354 6300 6404 308 -29 -436 O ATOM 698 CG2 THR A 402 -5.471 -17.893 -1.874 1.00 38.82 C ANISOU 698 CG2 THR A 402 4986 4829 4935 402 -325 -707 C ATOM 699 N ARG A 403 -6.683 -22.307 -0.635 1.00 55.43 N ANISOU 699 N ARG A 403 6999 6398 7666 450 -101 -491 N ATOM 700 CA ARG A 403 -6.448 -23.714 -0.336 1.00 63.06 C ANISOU 700 CA ARG A 403 7981 7284 8693 506 -37 -366 C ATOM 701 C ARG A 403 -6.933 -24.630 -1.451 1.00 66.12 C ANISOU 701 C ARG A 403 8397 7421 9304 628 -187 -474 C ATOM 702 O ARG A 403 -6.510 -25.789 -1.512 1.00 70.60 O ANISOU 702 O ARG A 403 9006 7937 9880 716 -177 -376 O ATOM 703 CB ARG A 403 -7.122 -24.099 0.983 1.00 70.94 C ANISOU 703 CB ARG A 403 8887 8230 9835 367 153 -294 C ATOM 704 CG ARG A 403 -6.622 -23.318 2.189 1.00 71.73 C ANISOU 704 CG ARG A 403 8958 8578 9719 246 318 -169 C ATOM 705 CD ARG A 403 -6.766 -24.127 3.470 1.00 81.63 C ANISOU 705 CD ARG A 403 10161 9820 11035 161 511 -22 C ATOM 706 NE ARG A 403 -8.155 -24.469 3.763 1.00 89.14 N ANISOU 706 NE ARG A 403 11019 10532 12318 70 552 -125 N ATOM 707 CZ ARG A 403 -8.914 -23.826 4.645 1.00 92.13 C ANISOU 707 CZ ARG A 403 11304 10918 12784 -88 665 -157 C ATOM 708 NH1 ARG A 403 -8.418 -22.803 5.328 1.00 89.03 N ANISOU 708 NH1 ARG A 403 10898 10758 12170 -174 751 -94 N ATOM 709 NH2 ARG A 403 -10.167 -24.208 4.848 1.00 98.35 N ANISOU 709 NH2 ARG A 403 12011 11479 13880 -162 695 -255 N ATOM 710 N THR A 404 -7.809 -24.139 -2.332 1.00 67.86 N ANISOU 710 N THR A 404 8595 7484 9704 636 -325 -675 N ATOM 711 CA THR A 404 -8.260 -24.953 -3.456 1.00 72.19 C ANISOU 711 CA THR A 404 9170 7798 10459 755 -477 -787 C ATOM 712 C THR A 404 -7.143 -25.180 -4.466 1.00 71.95 C ANISOU 712 C THR A 404 9255 7854 10229 920 -612 -751 C ATOM 713 O THR A 404 -7.167 -26.174 -5.202 1.00 76.42 O ANISOU 713 O THR A 404 9859 8265 10911 1035 -703 -772 O ATOM 714 CB THR A 404 -9.461 -24.297 -4.139 1.00 70.05 C ANISOU 714 CB THR A 404 8848 7349 10421 721 -593 -1013 C ATOM 715 OG1 THR A 404 -9.078 -23.017 -4.658 1.00 62.50 O ANISOU 715 OG1 THR A 404 7926 6542 9279 727 -685 -1085 O ATOM 716 CG2 THR A 404 -10.602 -24.116 -3.150 1.00 72.90 C ANISOU 716 CG2 THR A 404 9092 7616 10992 559 -461 -1054 C ATOM 717 N HIS A 405 -6.162 -24.279 -4.517 1.00 57.10 N ANISOU 717 N HIS A 405 7428 6217 8049 932 -626 -698 N ATOM 718 CA HIS A 405 -5.033 -24.428 -5.424 1.00 56.62 C ANISOU 718 CA HIS A 405 7476 6260 7775 1081 -745 -658 C ATOM 719 C HIS A 405 -3.892 -25.238 -4.825 1.00 57.96 C ANISOU 719 C HIS A 405 7697 6581 7743 1130 -642 -444 C ATOM 720 O HIS A 405 -3.081 -25.788 -5.579 1.00 59.81 O ANISOU 720 O HIS A 405 8017 6840 7867 1270 -738 -405 O ATOM 721 CB HIS A 405 -4.506 -23.051 -5.845 1.00 52.88 C ANISOU 721 CB HIS A 405 7043 5977 7072 1076 -819 -713 C ATOM 722 CG HIS A 405 -5.557 -22.149 -6.415 1.00 54.23 C ANISOU 722 CG HIS A 405 7169 6022 7414 1027 -921 -920 C ATOM 723 ND1 HIS A 405 -6.283 -22.470 -7.541 1.00 56.97 N ANISOU 723 ND1 HIS A 405 7524 6137 7984 1108 -1083 -1085 N ATOM 724 CD2 HIS A 405 -5.998 -20.932 -6.016 1.00 52.10 C ANISOU 724 CD2 HIS A 405 6847 5826 7122 907 -884 -991 C ATOM 725 CE1 HIS A 405 -7.130 -21.492 -7.810 1.00 55.38 C ANISOU 725 CE1 HIS A 405 7277 5873 7891 1041 -1143 -1248 C ATOM 726 NE2 HIS A 405 -6.977 -20.546 -6.900 1.00 52.45 N ANISOU 726 NE2 HIS A 405 6870 5683 7376 918 -1024 -1195 N ATOM 727 N THR A 406 -3.810 -25.323 -3.496 1.00 63.77 N ANISOU 727 N THR A 406 8382 7417 8428 1020 -451 -307 N ATOM 728 CA THR A 406 -2.734 -26.080 -2.864 1.00 66.90 C ANISOU 728 CA THR A 406 8825 7961 8631 1063 -347 -99 C ATOM 729 C THR A 406 -2.856 -27.567 -3.174 1.00 73.79 C ANISOU 729 C THR A 406 9721 8644 9673 1162 -373 -65 C ATOM 730 O THR A 406 -1.874 -28.215 -3.556 1.00 75.29 O ANISOU 730 O THR A 406 9992 8903 9712 1285 -416 31 O ATOM 731 CB THR A 406 -2.739 -25.842 -1.354 1.00 68.62 C ANISOU 731 CB THR A 406 8978 8311 8782 916 -135 30 C ATOM 732 OG1 THR A 406 -3.995 -26.260 -0.805 1.00 74.01 O ANISOU 732 OG1 THR A 406 9569 8785 9767 818 -58 -25 O ATOM 733 CG2 THR A 406 -2.524 -24.367 -1.046 1.00 62.20 C ANISOU 733 CG2 THR A 406 8148 7704 7783 822 -107 4 C ATOM 734 N GLY A 407 -4.056 -28.125 -3.017 1.00 86.03 N ANISOU 734 N GLY A 407 11200 9952 11537 1109 -349 -143 N ATOM 735 CA GLY A 407 -4.255 -29.523 -3.364 1.00 91.25 C ANISOU 735 CA GLY A 407 11880 10414 12376 1202 -381 -125 C ATOM 736 C GLY A 407 -4.235 -29.749 -4.864 1.00 89.13 C ANISOU 736 C GLY A 407 11674 10021 12171 1349 -592 -253 C ATOM 737 O GLY A 407 -3.502 -30.605 -5.366 1.00 90.96 O ANISOU 737 O GLY A 407 11979 10252 12330 1479 -649 -182 O ATOM 738 N LYS A 408 -5.034 -28.982 -5.598 1.00138.85 N ANISOU 738 N LYS A 408 22684 14600 15474 2359 -1241 -4245 N ATOM 739 CA LYS A 408 -5.088 -29.093 -7.050 1.00132.91 C ANISOU 739 CA LYS A 408 21646 14103 14751 2221 -986 -4410 C ATOM 740 C LYS A 408 -3.957 -28.301 -7.699 1.00125.44 C ANISOU 740 C LYS A 408 20374 13047 14242 2405 -1066 -4437 C ATOM 741 O LYS A 408 -2.946 -28.869 -8.112 1.00126.44 O ANISOU 741 O LYS A 408 20372 12969 14699 2355 -1118 -4523 O ATOM 742 CB LYS A 408 -6.440 -28.608 -7.575 1.00128.40 C ANISOU 742 CB LYS A 408 21030 14027 13728 2134 -701 -4398 C ATOM 743 N SER A 415 -3.655 -24.848 -18.104 1.00104.80 N ANISOU 743 N SER A 415 14009 13954 11855 2303 537 -4888 N ATOM 744 CA SER A 415 -3.087 -23.559 -17.727 1.00 98.02 C ANISOU 744 CA SER A 415 13001 12809 11434 2707 326 -4669 C ATOM 745 C SER A 415 -4.102 -22.720 -16.953 1.00 95.71 C ANISOU 745 C SER A 415 12842 12610 10913 2825 386 -4349 C ATOM 746 O SER A 415 -3.743 -22.030 -15.998 1.00 92.68 O ANISOU 746 O SER A 415 12700 11706 10809 3164 124 -4305 O ATOM 747 CB SER A 415 -2.605 -22.801 -18.965 1.00 93.60 C ANISOU 747 CB SER A 415 11689 12715 11161 2725 458 -4492 C ATOM 748 OG SER A 415 -1.826 -21.674 -18.600 1.00 88.11 O ANISOU 748 OG SER A 415 10865 11622 10989 3130 213 -4347 O ATOM 749 N CYS A 416 -5.366 -22.780 -17.373 1.00101.48 N ANISOU 749 N CYS A 416 13403 14015 11139 2539 737 -4140 N ATOM 750 CA CYS A 416 -6.428 -22.065 -16.675 1.00 99.80 C ANISOU 750 CA CYS A 416 13314 13932 10674 2615 829 -3843 C ATOM 751 C CYS A 416 -6.620 -22.643 -15.279 1.00102.61 C ANISOU 751 C CYS A 416 14434 13698 10855 2693 604 -4040 C ATOM 752 O CYS A 416 -6.774 -23.856 -15.112 1.00102.25 O ANISOU 752 O CYS A 416 14770 13553 10527 2465 604 -4292 O ATOM 753 CB CYS A 416 -7.734 -22.148 -17.472 1.00 95.09 C ANISOU 753 CB CYS A 416 12379 14205 9547 2257 1259 -3592 C ATOM 754 SG CYS A 416 -9.165 -21.301 -16.734 1.00 94.16 S ANISOU 754 SG CYS A 416 12356 14333 9086 2309 1431 -3205 S ATOM 755 N ARG A 417 -6.606 -21.771 -14.274 1.00 92.86 N ANISOU 755 N ARG A 417 13403 12079 9799 3012 415 -3927 N ATOM 756 CA ARG A 417 -6.722 -22.189 -12.884 1.00 96.99 C ANISOU 756 CA ARG A 417 14623 12052 10175 3117 173 -4095 C ATOM 757 C ARG A 417 -8.158 -22.162 -12.374 1.00 99.58 C ANISOU 757 C ARG A 417 15160 12717 9960 2965 390 -3907 C ATOM 758 O ARG A 417 -8.379 -22.334 -11.171 1.00102.06 O ANISOU 758 O ARG A 417 16013 12642 10124 3065 210 -3994 O ATOM 759 CB ARG A 417 -5.835 -21.313 -11.995 1.00 94.78 C ANISOU 759 CB ARG A 417 14479 11145 10388 3541 -178 -4135 C ATOM 760 CG ARG A 417 -4.381 -21.260 -12.439 1.00 92.49 C ANISOU 760 CG ARG A 417 13986 10493 10664 3720 -412 -4308 C ATOM 761 CD ARG A 417 -3.793 -22.655 -12.575 1.00 97.18 C ANISOU 761 CD ARG A 417 14813 10871 11241 3443 -504 -4516 C ATOM 762 NE ARG A 417 -3.693 -23.336 -11.288 1.00103.03 N ANISOU 762 NE ARG A 417 16037 11170 11939 3288 -707 -4440 N ATOM 763 CZ ARG A 417 -2.608 -23.325 -10.521 1.00104.45 C ANISOU 763 CZ ARG A 417 16292 10877 12516 3332 -993 -4343 C ATOM 764 NH1 ARG A 417 -1.524 -22.670 -10.913 1.00100.39 N ANISOU 764 NH1 ARG A 417 15450 10223 12469 3484 -1115 -4290 N ATOM 765 NH2 ARG A 417 -2.605 -23.971 -9.363 1.00110.01 N ANISOU 765 NH2 ARG A 417 17362 11314 13121 3215 -1139 -4281 N ATOM 766 N TRP A 418 -9.141 -21.947 -13.260 1.00 96.71 N ANISOU 766 N TRP A 418 14369 13088 9288 2723 773 -3644 N ATOM 767 CA TRP A 418 -10.549 -22.002 -12.902 1.00100.27 C ANISOU 767 CA TRP A 418 14983 13918 9195 2540 1013 -3461 C ATOM 768 C TRP A 418 -11.106 -23.400 -13.154 1.00109.08 C ANISOU 768 C TRP A 418 16360 15268 9818 2149 1165 -3632 C ATOM 769 O TRP A 418 -10.627 -24.115 -14.041 1.00109.20 O ANISOU 769 O TRP A 418 16181 15425 9886 1955 1225 -3801 O ATOM 770 CB TRP A 418 -11.344 -20.975 -13.706 1.00 95.06 C ANISOU 770 CB TRP A 418 13699 13939 8481 2491 1350 -3051 C ATOM 771 CG TRP A 418 -11.074 -19.558 -13.297 1.00 88.67 C ANISOU 771 CG TRP A 418 12667 12904 8118 2863 1245 -2848 C ATOM 772 CD1 TRP A 418 -9.968 -18.817 -13.594 1.00 83.46 C ANISOU 772 CD1 TRP A 418 11675 11976 8060 3135 1072 -2845 C ATOM 773 CD2 TRP A 418 -11.927 -18.710 -12.518 1.00 88.08 C ANISOU 773 CD2 TRP A 418 12673 12845 7948 3001 1317 -2632 C ATOM 774 NE1 TRP A 418 -10.078 -17.562 -13.047 1.00 80.64 N ANISOU 774 NE1 TRP A 418 11181 11452 8005 3432 1033 -2646 N ATOM 775 CE2 TRP A 418 -11.272 -17.470 -12.381 1.00 83.38 C ANISOU 775 CE2 TRP A 418 11774 11968 7938 3356 1185 -2522 C ATOM 776 CE3 TRP A 418 -13.181 -18.879 -11.922 1.00 91.34 C ANISOU 776 CE3 TRP A 418 13376 13479 7849 2857 1484 -2531 C ATOM 777 CZ2 TRP A 418 -11.827 -16.405 -11.674 1.00 82.33 C ANISOU 777 CZ2 TRP A 418 11610 11759 7913 3565 1226 -2335 C ATOM 778 CZ3 TRP A 418 -13.731 -17.820 -11.220 1.00 90.29 C ANISOU 778 CZ3 TRP A 418 13218 13284 7803 3067 1520 -2339 C ATOM 779 CH2 TRP A 418 -13.055 -16.600 -11.103 1.00 85.84 C ANISOU 779 CH2 TRP A 418 12340 12428 7847 3416 1396 -2252 C ATOM 780 N PRO A 419 -12.111 -23.820 -12.385 1.00103.29 N ANISOU 780 N PRO A 419 16056 14575 8614 2023 1233 -3605 N ATOM 781 CA PRO A 419 -12.639 -25.182 -12.543 1.00112.62 C ANISOU 781 CA PRO A 419 17432 15885 9474 1565 1359 -3701 C ATOM 782 C PRO A 419 -13.276 -25.387 -13.911 1.00115.39 C ANISOU 782 C PRO A 419 17305 16957 9583 1207 1748 -3546 C ATOM 783 O PRO A 419 -14.113 -24.596 -14.353 1.00111.60 O ANISOU 783 O PRO A 419 16454 16984 8966 1154 1994 -3191 O ATOM 784 CB PRO A 419 -13.670 -25.295 -11.414 1.00115.97 C ANISOU 784 CB PRO A 419 18161 16230 9674 1419 1339 -3521 C ATOM 785 CG PRO A 419 -14.034 -23.885 -11.083 1.00 96.30 C ANISOU 785 CG PRO A 419 15558 13846 7185 1742 1378 -3286 C ATOM 786 CD PRO A 419 -12.782 -23.091 -11.294 1.00 90.20 C ANISOU 786 CD PRO A 419 14661 12785 6825 2211 1184 -3438 C ATOM 787 N SER A 420 -12.862 -26.466 -14.580 1.00140.23 N ANISOU 787 N SER A 420 20457 20065 12761 969 1776 -3747 N ATOM 788 CA SER A 420 -13.378 -26.876 -15.887 1.00145.18 C ANISOU 788 CA SER A 420 20639 21245 13278 660 2047 -3557 C ATOM 789 C SER A 420 -13.154 -25.785 -16.939 1.00139.58 C ANISOU 789 C SER A 420 19199 21115 12719 713 2218 -3393 C ATOM 790 O SER A 420 -14.083 -25.142 -17.433 1.00140.38 O ANISOU 790 O SER A 420 18935 21682 12721 599 2431 -2970 O ATOM 791 CB SER A 420 -14.858 -27.264 -15.800 1.00152.05 C ANISOU 791 CB SER A 420 21628 22300 13844 460 2200 -3186 C ATOM 792 OG SER A 420 -15.000 -28.641 -15.502 1.00160.21 O ANISOU 792 OG SER A 420 23017 23070 14784 375 2082 -3344 O ATOM 793 N CYS A 421 -11.877 -25.607 -17.271 1.00125.96 N ANISOU 793 N CYS A 421 17265 19297 11300 914 2088 -3719 N ATOM 794 CA CYS A 421 -11.473 -24.728 -18.359 1.00118.11 C ANISOU 794 CA CYS A 421 15547 18832 10499 979 2231 -3582 C ATOM 795 C CYS A 421 -10.009 -24.992 -18.672 1.00114.84 C ANISOU 795 C CYS A 421 15062 17975 10596 1115 1986 -3885 C ATOM 796 O CYS A 421 -9.201 -25.188 -17.760 1.00114.24 O ANISOU 796 O CYS A 421 15453 17117 10836 1372 1641 -4107 O ATOM 797 CB CYS A 421 -11.682 -23.249 -18.015 1.00110.73 C ANISOU 797 CB CYS A 421 14383 17912 9777 1300 2203 -3172 C ATOM 798 SG CYS A 421 -11.542 -22.156 -19.448 1.00104.82 S ANISOU 798 SG CYS A 421 12672 17900 9255 1290 2439 -2788 S ATOM 799 N GLN A 422 -9.678 -24.995 -19.958 1.00111.35 N ANISOU 799 N GLN A 422 14025 18058 10224 937 2166 -3887 N ATOM 800 CA GLN A 422 -8.309 -25.232 -20.395 1.00109.48 C ANISOU 800 CA GLN A 422 13648 17486 10463 1040 1969 -4169 C ATOM 801 C GLN A 422 -7.590 -23.917 -20.675 1.00101.91 C ANISOU 801 C GLN A 422 12227 16499 9996 1374 1852 -3896 C ATOM 802 O GLN A 422 -7.846 -23.261 -21.684 1.00100.08 O ANISOU 802 O GLN A 422 11339 16960 9725 1275 2090 -3600 O ATOM 803 CB GLN A 422 -8.291 -26.118 -21.642 1.00114.81 C ANISOU 803 CB GLN A 422 13951 18738 10935 629 2229 -4398 C ATOM 804 N LEU A 431 -2.365 -16.100 -19.390 1.00 93.24 N ANISOU 804 N LEU A 431 9567 13082 12775 3984 492 -2729 N ATOM 805 CA LEU A 431 -3.507 -16.663 -18.683 1.00 95.99 C ANISOU 805 CA LEU A 431 10405 13503 12564 3805 607 -2778 C ATOM 806 C LEU A 431 -4.291 -15.571 -17.965 1.00 95.14 C ANISOU 806 C LEU A 431 10287 13353 12510 4002 669 -2469 C ATOM 807 O LEU A 431 -5.378 -15.817 -17.443 1.00 97.37 O ANISOU 807 O LEU A 431 10872 13789 12333 3863 811 -2421 O ATOM 808 CB LEU A 431 -3.051 -17.730 -17.684 1.00 98.83 C ANISOU 808 CB LEU A 431 11543 13189 12820 3829 314 -3250 C ATOM 809 N VAL A 432 -3.733 -14.360 -17.946 1.00110.13 N ANISOU 809 N VAL A 432 13349 15831 12662 156 1413 352 N ATOM 810 CA VAL A 432 -4.376 -13.257 -17.238 1.00106.46 C ANISOU 810 CA VAL A 432 13055 14934 12460 281 797 196 C ATOM 811 C VAL A 432 -5.670 -12.854 -17.932 1.00107.97 C ANISOU 811 C VAL A 432 13322 14936 12766 224 532 -47 C ATOM 812 O VAL A 432 -6.661 -12.511 -17.278 1.00103.51 O ANISOU 812 O VAL A 432 12890 14028 12411 477 333 -405 O ATOM 813 CB VAL A 432 -3.409 -12.066 -17.114 1.00108.83 C ANISOU 813 CB VAL A 432 13385 15164 12802 40 150 634 C ATOM 814 N ARG A 433 -5.680 -12.876 -19.266 1.00129.20 N ANISOU 814 N ARG A 433 15928 17845 15318 -108 518 144 N ATOM 815 CA ARG A 433 -6.877 -12.490 -20.007 1.00131.66 C ANISOU 815 CA ARG A 433 16305 17994 15727 -187 263 -64 C ATOM 816 C ARG A 433 -8.024 -13.449 -19.723 1.00128.42 C ANISOU 816 C ARG A 433 15919 17513 15363 151 783 -586 C ATOM 817 O ARG A 433 -9.154 -13.023 -19.454 1.00127.88 O ANISOU 817 O ARG A 433 15975 17124 15491 313 527 -918 O ATOM 818 CB ARG A 433 -6.574 -12.443 -21.505 1.00138.78 C ANISOU 818 CB ARG A 433 17095 19187 16447 -611 213 259 C ATOM 819 N HIS A 434 -7.747 -14.754 -19.783 1.00102.15 N ANISOU 819 N HIS A 434 12473 14483 11855 259 1517 -664 N ATOM 820 CA HIS A 434 -8.767 -15.758 -19.493 1.00101.85 C ANISOU 820 CA HIS A 434 12448 14402 11847 584 2060 -1150 C ATOM 821 C HIS A 434 -9.260 -15.641 -18.057 1.00 88.73 C ANISOU 821 C HIS A 434 10914 12405 10394 992 2014 -1494 C ATOM 822 O HIS A 434 -10.468 -15.709 -17.800 1.00 77.17 O ANISOU 822 O HIS A 434 9539 10705 9076 1218 2033 -1909 O ATOM 823 CB HIS A 434 -8.208 -17.159 -19.762 1.00110.75 C ANISOU 823 CB HIS A 434 13420 15924 12735 616 2843 -1124 C ATOM 824 CG HIS A 434 -8.934 -18.254 -19.042 1.00113.46 C ANISOU 824 CG HIS A 434 13776 16221 13112 1019 3447 -1591 C ATOM 825 ND1 HIS A 434 -10.045 -18.880 -19.565 1.00115.26 N ANISOU 825 ND1 HIS A 434 14003 16452 13340 1104 3758 -1934 N ATOM 826 CD2 HIS A 434 -8.706 -18.836 -17.841 1.00110.31 C ANISOU 826 CD2 HIS A 434 13391 15775 12746 1358 3796 -1769 C ATOM 827 CE1 HIS A 434 -10.469 -19.800 -18.718 1.00110.19 C ANISOU 827 CE1 HIS A 434 13384 15753 12731 1482 4152 -2225 C ATOM 828 NE2 HIS A 434 -9.675 -19.793 -17.663 1.00107.85 N ANISOU 828 NE2 HIS A 434 13089 15439 12450 1635 4135 -2122 N ATOM 829 N HIS A 435 -8.339 -15.461 -17.106 1.00102.35 N ANISOU 829 N HIS A 435 12648 14106 12136 1090 1952 -1328 N ATOM 830 CA HIS A 435 -8.727 -15.343 -15.704 1.00 91.38 C ANISOU 830 CA HIS A 435 11375 12408 10937 1477 1907 -1636 C ATOM 831 C HIS A 435 -9.602 -14.117 -15.472 1.00 92.29 C ANISOU 831 C HIS A 435 11650 12114 11301 1504 1211 -1783 C ATOM 832 O HIS A 435 -10.601 -14.185 -14.745 1.00 87.01 O ANISOU 832 O HIS A 435 11083 11179 10800 1824 1244 -2204 O ATOM 833 CB HIS A 435 -7.482 -15.288 -14.818 1.00 86.02 C ANISOU 833 CB HIS A 435 10670 11793 10220 1533 1918 -1377 C ATOM 834 CG HIS A 435 -6.756 -16.593 -14.708 1.00 80.67 C ANISOU 834 CG HIS A 435 9855 11459 9335 1622 2659 -1337 C ATOM 835 ND1 HIS A 435 -5.462 -16.687 -14.244 1.00 79.39 N ANISOU 835 ND1 HIS A 435 9629 11464 9073 1585 2746 -1021 N ATOM 836 CD2 HIS A 435 -7.146 -17.858 -14.993 1.00 74.45 C ANISOU 836 CD2 HIS A 435 8984 10877 8425 1751 3346 -1576 C ATOM 837 CE1 HIS A 435 -5.085 -17.953 -14.251 1.00 76.56 C ANISOU 837 CE1 HIS A 435 9152 11399 8537 1686 3453 -1067 C ATOM 838 NE2 HIS A 435 -6.088 -18.684 -14.700 1.00 75.56 N ANISOU 838 NE2 HIS A 435 9013 11302 8395 1788 3828 -1402 N ATOM 839 N ASN A 436 -9.242 -12.985 -16.082 1.00 89.87 N ANISOU 839 N ASN A 436 11369 11754 11022 1171 573 -1439 N ATOM 840 CA ASN A 436 -10.013 -11.762 -15.891 1.00 92.34 C ANISOU 840 CA ASN A 436 11834 11679 11571 1176 -125 -1551 C ATOM 841 C ASN A 436 -11.401 -11.871 -16.509 1.00 95.35 C ANISOU 841 C ASN A 436 12261 11941 12027 1214 -104 -1901 C ATOM 842 O ASN A 436 -12.354 -11.265 -16.003 1.00 94.18 O ANISOU 842 O ASN A 436 12247 11442 12094 1397 -452 -2195 O ATOM 843 CB ASN A 436 -9.258 -10.568 -16.481 1.00 98.43 C ANISOU 843 CB ASN A 436 12612 12447 12341 787 -795 -1078 C ATOM 844 N MET A 437 -11.540 -12.636 -17.594 1.00104.04 N ANISOU 844 N MET A 437 13250 13328 12950 1046 301 -1878 N ATOM 845 CA MET A 437 -12.838 -12.771 -18.243 1.00108.68 C ANISOU 845 CA MET A 437 13874 13821 13597 1066 338 -2198 C ATOM 846 C MET A 437 -13.808 -13.629 -17.441 1.00106.25 C ANISOU 846 C MET A 437 13610 13386 13374 1494 815 -2721 C ATOM 847 O MET A 437 -15.020 -13.533 -17.655 1.00108.41 O ANISOU 847 O MET A 437 13954 13472 13764 1586 733 -3050 O ATOM 848 CB MET A 437 -12.664 -13.353 -19.647 1.00113.45 C ANISOU 848 CB MET A 437 14343 14782 13982 758 638 -2011 C ATOM 849 N HIS A 438 -13.307 -14.459 -16.523 1.00 87.88 N ANISOU 849 N HIS A 438 11243 11157 10992 1756 1307 -2806 N ATOM 850 CA HIS A 438 -14.175 -15.309 -15.717 1.00 87.83 C ANISOU 850 CA HIS A 438 11272 11040 11059 2167 1780 -3293 C ATOM 851 C HIS A 438 -15.017 -14.529 -14.718 1.00 83.58 C ANISOU 851 C HIS A 438 10898 10072 10787 2439 1351 -3602 C ATOM 852 O HIS A 438 -15.902 -15.121 -14.091 1.00 77.07 O ANISOU 852 O HIS A 438 10118 9120 10045 2772 1675 -4027 O ATOM 853 CB HIS A 438 -13.348 -16.356 -14.971 1.00 88.02 C ANISOU 853 CB HIS A 438 11210 11280 10955 2368 2393 -3278 C ATOM 854 CG HIS A 438 -13.023 -17.565 -15.790 1.00 95.32 C ANISOU 854 CG HIS A 438 11980 12599 11637 2260 3051 -3209 C ATOM 855 ND1 HIS A 438 -13.933 -18.575 -16.018 1.00 94.57 N ANISOU 855 ND1 HIS A 438 11995 12522 11415 2364 3197 -3077 N ATOM 856 CD2 HIS A 438 -11.889 -17.927 -16.434 1.00100.80 C ANISOU 856 CD2 HIS A 438 12540 13646 12113 1999 3260 -2818 C ATOM 857 CE1 HIS A 438 -13.374 -19.506 -16.770 1.00 96.68 C ANISOU 857 CE1 HIS A 438 12113 13181 11441 2236 3434 -2791 C ATOM 858 NE2 HIS A 438 -12.134 -19.137 -17.036 1.00100.68 N ANISOU 858 NE2 HIS A 438 12462 13884 11909 2011 3668 -2750 N ATOM 859 N GLN A 439 -14.769 -13.236 -14.549 1.00119.57 N ANISOU 859 N GLN A 439 15546 14407 15477 2305 637 -3395 N ATOM 860 CA GLN A 439 -15.540 -12.435 -13.608 1.00118.59 C ANISOU 860 CA GLN A 439 15579 13872 15608 2554 194 -3675 C ATOM 861 C GLN A 439 -15.958 -11.110 -14.235 1.00125.74 C ANISOU 861 C GLN A 439 16575 14554 16646 2303 -572 -3553 C ATOM 862 O GLN A 439 -16.143 -11.019 -15.449 1.00129.84 O ANISOU 862 O GLN A 439 17046 15204 17082 2008 -652 -3417 O ATOM 863 CB GLN A 439 -14.734 -12.186 -12.331 1.00114.70 C ANISOU 863 CB GLN A 439 15125 13277 15177 2745 96 -3588 C TER 864 GLN A 439 ATOM 865 P DG B 2 -32.893 -34.076 -3.676 1.00106.24 P ANISOU 865 P DG B 2 14418 13300 12648 -1672 1501 -3428 P ATOM 866 OP1 DG B 2 -33.225 -33.906 -2.243 1.00114.23 O ANISOU 866 OP1 DG B 2 15353 14517 13532 -1829 1595 -3541 O ATOM 867 OP2 DG B 2 -32.867 -32.899 -4.573 1.00 99.03 O ANISOU 867 OP2 DG B 2 13503 12297 11826 -1413 1280 -3405 O ATOM 868 O5' DG B 2 -31.483 -34.821 -3.793 1.00100.30 O ANISOU 868 O5' DG B 2 13836 12408 11868 -1748 1582 -3259 O ATOM 869 C5' DG B 2 -31.419 -36.243 -3.797 1.00102.48 C ANISOU 869 C5' DG B 2 14188 12633 12116 -1936 1782 -3198 C ATOM 870 C4' DG B 2 -30.011 -36.714 -4.114 1.00 96.31 C ANISOU 870 C4' DG B 2 13596 11666 11329 -1960 1842 -3012 C ATOM 871 O4' DG B 2 -29.587 -36.110 -5.356 1.00 85.99 O ANISOU 871 O4' DG B 2 12326 10190 10155 -1709 1668 -2931 O ATOM 872 C3' DG B 2 -28.972 -36.354 -3.056 1.00 96.18 C ANISOU 872 C3' DG B 2 13653 11705 11185 -2072 1875 -2967 C ATOM 873 O3' DG B 2 -28.419 -37.536 -2.484 1.00100.34 O ANISOU 873 O3' DG B 2 14325 12199 11599 -2322 2103 -2866 O ATOM 874 C2' DG B 2 -27.908 -35.526 -3.785 1.00 85.43 C ANISOU 874 C2' DG B 2 12372 10179 9909 -1875 1719 -2859 C ATOM 875 C1' DG B 2 -28.262 -35.646 -5.266 1.00 79.77 C ANISOU 875 C1' DG B 2 11648 9307 9355 -1671 1631 -2816 C ATOM 876 N9 DG B 2 -28.189 -34.367 -5.967 1.00 71.45 N ANISOU 876 N9 DG B 2 10533 8221 8394 -1407 1383 -2832 N ATOM 877 C8 DG B 2 -29.131 -33.366 -5.949 1.00 70.94 C ANISOU 877 C8 DG B 2 10331 8280 8344 -1276 1220 -2965 C ATOM 878 N7 DG B 2 -28.801 -32.329 -6.667 1.00 64.24 N ANISOU 878 N7 DG B 2 9490 7355 7565 -1052 1017 -2927 N ATOM 879 C5 DG B 2 -27.561 -32.660 -7.195 1.00 59.35 C ANISOU 879 C5 DG B 2 8993 6563 6995 -1025 1040 -2771 C ATOM 880 C6 DG B 2 -26.711 -31.923 -8.053 1.00 52.59 C ANISOU 880 C6 DG B 2 8186 5570 6226 -822 876 -2669 C ATOM 881 O6 DG B 2 -26.893 -30.795 -8.531 1.00 50.10 O ANISOU 881 O6 DG B 2 7836 5259 5941 -622 664 -2691 O ATOM 882 N1 DG B 2 -25.545 -32.624 -8.349 1.00 48.41 N ANISOU 882 N1 DG B 2 7785 4869 5740 -876 998 -2507 N ATOM 883 C2 DG B 2 -25.238 -33.878 -7.877 1.00 54.20 C ANISOU 883 C2 DG B 2 8632 5546 6417 -1100 1254 -2429 C ATOM 884 N2 DG B 2 -24.065 -34.391 -8.274 1.00 53.05 N ANISOU 884 N2 DG B 2 8655 5183 6318 -1113 1366 -2224 N ATOM 885 N3 DG B 2 -26.027 -34.581 -7.072 1.00 61.26 N ANISOU 885 N3 DG B 2 9492 6572 7211 -1297 1399 -2525 N ATOM 886 C4 DG B 2 -27.168 -33.912 -6.773 1.00 63.60 C ANISOU 886 C4 DG B 2 9625 7057 7485 -1244 1276 -2703 C ATOM 887 P DC B 3 -27.657 -37.467 -1.071 1.00106.82 P ANISOU 887 P DC B 3 15222 13147 12217 -2539 2182 -2838 P ATOM 888 OP1 DC B 3 -27.722 -38.806 -0.449 1.00115.77 O ANISOU 888 OP1 DC B 3 16447 14320 13220 -2806 2424 -2783 O ATOM 889 OP2 DC B 3 -28.176 -36.292 -0.337 1.00108.51 O ANISOU 889 OP2 DC B 3 15274 13568 12386 -2474 2029 -2993 O ATOM 890 O5' DC B 3 -26.140 -37.158 -1.464 1.00 99.83 O ANISOU 890 O5' DC B 3 14533 12049 11349 -2487 2141 -2661 O ATOM 891 C5' DC B 3 -25.405 -38.075 -2.266 1.00 95.91 C ANISOU 891 C5' DC B 3 14240 11284 10919 -2499 2280 -2474 C ATOM 892 C4' DC B 3 -24.076 -37.470 -2.675 1.00 88.41 C ANISOU 892 C4' DC B 3 13445 10119 10026 -2399 2198 -2321 C ATOM 893 O4' DC B 3 -24.314 -36.422 -3.635 1.00 79.00 O ANISOU 893 O4' DC B 3 12113 8897 9005 -2102 1971 -2380 O ATOM 894 C3' DC B 3 -23.293 -36.839 -1.526 1.00 90.72 C ANISOU 894 C3' DC B 3 13707 10561 10201 -2487 2093 -2194 C ATOM 895 O3' DC B 3 -22.147 -37.624 -1.216 1.00 91.74 O ANISOU 895 O3' DC B 3 13899 10604 10354 -2550 2159 -1744 O ATOM 896 C2' DC B 3 -22.902 -35.439 -2.018 1.00 82.54 C ANISOU 896 C2' DC B 3 12674 9446 9240 -2301 1881 -2312 C ATOM 897 C1' DC B 3 -23.375 -35.391 -3.469 1.00 74.35 C ANISOU 897 C1' DC B 3 11571 8264 8417 -2036 1827 -2336 C ATOM 898 N1 DC B 3 -24.045 -34.109 -3.817 1.00 68.12 N ANISOU 898 N1 DC B 3 10563 7607 7714 -1795 1576 -2496 N ATOM 899 C2 DC B 3 -23.575 -33.342 -4.889 1.00 59.95 C ANISOU 899 C2 DC B 3 9521 6420 6836 -1540 1408 -2432 C ATOM 900 O2 DC B 3 -22.600 -33.743 -5.536 1.00 57.48 O ANISOU 900 O2 DC B 3 9373 5862 6604 -1509 1478 -2237 O ATOM 901 N3 DC B 3 -24.204 -32.178 -5.187 1.00 55.55 N ANISOU 901 N3 DC B 3 8793 5976 6339 -1328 1178 -2566 N ATOM 902 C4 DC B 3 -25.253 -31.782 -4.465 1.00 59.55 C ANISOU 902 C4 DC B 3 9159 6703 6765 -1355 1131 -2738 C ATOM 903 N4 DC B 3 -25.842 -30.630 -4.797 1.00 56.20 N ANISOU 903 N4 DC B 3 8623 6338 6393 -1143 921 -2829 N ATOM 904 C5 DC B 3 -25.745 -32.551 -3.370 1.00 68.28 C ANISOU 904 C5 DC B 3 10253 7963 7727 -1604 1308 -2804 C ATOM 905 C6 DC B 3 -25.116 -33.693 -3.084 1.00 71.80 C ANISOU 905 C6 DC B 3 10852 8326 8102 -1820 1517 -2685 C ATOM 906 P DG B 4 -21.371 -37.395 0.173 1.00100.71 P ANISOU 906 P DG B 4 14997 11922 11348 -2708 2084 -1526 P ATOM 907 OP1 DG B 4 -20.699 -38.662 0.533 1.00107.28 O ANISOU 907 OP1 DG B 4 15870 12708 12185 -2829 2236 -1122 O ATOM 908 OP2 DG B 4 -22.324 -36.771 1.116 1.00104.68 O ANISOU 908 OP2 DG B 4 15409 12704 11660 -2824 2036 -1878 O ATOM 909 O5' DG B 4 -20.253 -36.309 -0.183 1.00 92.06 O ANISOU 909 O5' DG B 4 13934 10687 10356 -2550 1875 -1377 O ATOM 910 C5' DG B 4 -19.152 -36.662 -1.013 1.00 86.44 C ANISOU 910 C5' DG B 4 13305 9704 9834 -2417 1892 -1009 C ATOM 911 C4' DG B 4 -18.485 -35.422 -1.577 1.00 77.67 C ANISOU 911 C4' DG B 4 12210 8468 8835 -2230 1685 -1014 C ATOM 912 O4' DG B 4 -19.495 -34.556 -2.143 1.00 72.84 O ANISOU 912 O4' DG B 4 11570 7884 8220 -2117 1609 -1468 O ATOM 913 C3' DG B 4 -17.708 -34.591 -0.556 1.00 78.40 C ANISOU 913 C3' DG B 4 12263 8691 8837 -2315 1495 -882 C ATOM 914 O3' DG B 4 -16.330 -34.538 -0.918 1.00 75.83 O ANISOU 914 O3' DG B 4 11979 8163 8671 -2219 1428 -463 O ATOM 915 C2' DG B 4 -18.367 -33.204 -0.586 1.00 74.05 C ANISOU 915 C2' DG B 4 11671 8240 8223 -2238 1319 -1306 C ATOM 916 C1' DG B 4 -19.191 -33.213 -1.868 1.00 68.17 C ANISOU 916 C1' DG B 4 10946 7354 7601 -2061 1389 -1581 C ATOM 917 N9 DG B 4 -20.454 -32.492 -1.735 1.00 66.01 N ANISOU 917 N9 DG B 4 10607 7251 7221 -2063 1346 -2066 N ATOM 918 C8 DG B 4 -21.442 -32.735 -0.814 1.00 72.32 C ANISOU 918 C8 DG B 4 11341 8300 7836 -2238 1427 -2298 C ATOM 919 N7 DG B 4 -22.467 -31.940 -0.926 1.00 70.72 N ANISOU 919 N7 DG B 4 10968 8243 7660 -2090 1323 -2562 N ATOM 920 C5 DG B 4 -22.138 -31.109 -1.988 1.00 62.70 C ANISOU 920 C5 DG B 4 9922 7073 6830 -1822 1160 -2536 C ATOM 921 C6 DG B 4 -22.866 -30.044 -2.569 1.00 57.78 C ANISOU 921 C6 DG B 4 9114 6513 6326 -1540 963 -2667 C ATOM 922 O6 DG B 4 -23.981 -29.611 -2.247 1.00 61.42 O ANISOU 922 O6 DG B 4 9424 7151 6760 -1472 904 -2823 O ATOM 923 N1 DG B 4 -22.172 -29.463 -3.626 1.00 50.57 N ANISOU 923 N1 DG B 4 8234 5409 5573 -1331 833 -2577 N ATOM 924 C2 DG B 4 -20.933 -29.861 -4.067 1.00 49.01 C ANISOU 924 C2 DG B 4 8223 4964 5437 -1377 901 -2374 C ATOM 925 N2 DG B 4 -20.423 -29.177 -5.102 1.00 44.35 N ANISOU 925 N2 DG B 4 7618 4217 5015 -1140 759 -2303 N ATOM 926 N3 DG B 4 -20.239 -30.859 -3.532 1.00 52.91 N ANISOU 926 N3 DG B 4 8924 5345 5834 -1635 1093 -2223 N ATOM 927 C4 DG B 4 -20.901 -31.435 -2.499 1.00 59.72 C ANISOU 927 C4 DG B 4 9754 6420 6516 -1855 1207 -2324 C ATOM 928 P DA B 5 -15.288 -33.679 -0.046 1.00 78.28 P ANISOU 928 P DA B 5 12261 8548 8935 -2287 1203 -244 P ATOM 929 OP1 DA B 5 -13.968 -34.336 -0.147 1.00 81.39 O ANISOU 929 OP1 DA B 5 12680 8771 9474 -2278 1241 297 O ATOM 930 OP2 DA B 5 -15.876 -33.437 1.290 1.00 84.11 O ANISOU 930 OP2 DA B 5 12954 9583 9421 -2505 1152 -445 O ATOM 931 O5' DA B 5 -15.208 -32.287 -0.823 1.00 69.40 O ANISOU 931 O5' DA B 5 11141 7318 7908 -2077 1004 -457 O ATOM 932 C5' DA B 5 -14.910 -32.269 -2.212 1.00 62.77 C ANISOU 932 C5' DA B 5 10352 6205 7294 -1839 1038 -391 C ATOM 933 C4' DA B 5 -15.157 -30.892 -2.799 1.00 56.19 C ANISOU 933 C4' DA B 5 9511 5334 6505 -1669 851 -701 C ATOM 934 O4' DA B 5 -16.561 -30.560 -2.673 1.00 55.08 O ANISOU 934 O4' DA B 5 9335 5367 6225 -1702 869 -1201 O ATOM 935 C3' DA B 5 -14.371 -29.765 -2.131 1.00 55.93 C ANISOU 935 C3' DA B 5 9449 5368 6435 -1699 600 -609 C ATOM 936 O3' DA B 5 -13.559 -29.101 -3.091 1.00 51.89 O ANISOU 936 O3' DA B 5 8962 4624 6129 -1483 486 -463 O ATOM 937 C2' DA B 5 -15.438 -28.835 -1.537 1.00 55.84 C ANISOU 937 C2' DA B 5 9400 5587 6229 -1764 496 -1094 C ATOM 938 C1' DA B 5 -16.710 -29.216 -2.289 1.00 52.16 C ANISOU 938 C1' DA B 5 8931 5114 5775 -1685 658 -1453 C ATOM 939 N9 DA B 5 -17.910 -29.120 -1.460 1.00 54.01 N ANISOU 939 N9 DA B 5 9116 5609 5795 -1832 698 -1827 N ATOM 940 C8 DA B 5 -18.164 -29.815 -0.311 1.00 60.41 C ANISOU 940 C8 DA B 5 9906 6622 6426 -2061 793 -1775 C ATOM 941 N7 DA B 5 -19.324 -29.538 0.233 1.00 63.94 N ANISOU 941 N7 DA B 5 10310 7278 6707 -2143 824 -2162 N ATOM 942 C5 DA B 5 -19.874 -28.595 -0.618 1.00 58.10 C ANISOU 942 C5 DA B 5 9514 6488 6074 -1920 727 -2440 C ATOM 943 C6 DA B 5 -21.098 -27.898 -0.595 1.00 57.46 C ANISOU 943 C6 DA B 5 9203 6600 6029 -1718 645 -2655 C ATOM 944 N6 DA B 5 -22.019 -28.060 0.362 1.00 62.32 N ANISOU 944 N6 DA B 5 9731 7442 6505 -1820 710 -2781 N ATOM 945 N1 DA B 5 -21.339 -27.024 -1.594 1.00 52.28 N ANISOU 945 N1 DA B 5 8442 5868 5554 -1412 488 -2706 N ATOM 946 C2 DA B 5 -20.414 -26.865 -2.549 1.00 47.06 C ANISOU 946 C2 DA B 5 7860 4982 5040 -1303 431 -2574 C ATOM 947 N3 DA B 5 -19.228 -27.461 -2.677 1.00 46.47 N ANISOU 947 N3 DA B 5 7994 4690 4972 -1454 517 -2366 N ATOM 948 C4 DA B 5 -19.016 -28.324 -1.669 1.00 52.08 C ANISOU 948 C4 DA B 5 8835 5457 5497 -1764 657 -2292 C ATOM 949 P DA B 6 -12.454 -28.037 -2.615 1.00 58.67 P ANISOU 949 P DA B 6 9800 5478 7014 -1488 222 -250 P ATOM 950 OP1 DA B 6 -11.358 -28.048 -3.607 1.00 55.05 O ANISOU 950 OP1 DA B 6 9367 4735 6814 -1293 210 111 O ATOM 951 OP2 DA B 6 -12.155 -28.297 -1.190 1.00 65.91 O ANISOU 951 OP2 DA B 6 10691 6601 7751 -1748 174 -79 O ATOM 952 O5' DA B 6 -13.220 -26.639 -2.710 1.00 54.80 O ANISOU 952 O5' DA B 6 9296 5081 6443 -1409 46 -733 O ATOM 953 C5' DA B 6 -13.930 -26.307 -3.892 1.00 47.90 C ANISOU 953 C5' DA B 6 8438 4087 5673 -1199 89 -1042 C ATOM 954 C4' DA B 6 -14.914 -25.182 -3.632 1.00 46.33 C ANISOU 954 C4' DA B 6 8211 4056 5337 -1194 -36 -1537 C ATOM 955 O4' DA B 6 -15.992 -25.661 -2.804 1.00 50.22 O ANISOU 955 O4' DA B 6 8676 4785 5621 -1375 83 -1794 O ATOM 956 C3' DA B 6 -14.333 -23.972 -2.899 1.00 46.96 C ANISOU 956 C3' DA B 6 8284 4219 5341 -1243 -292 -1528 C ATOM 957 O3' DA B 6 -14.191 -22.882 -3.806 1.00 42.93 O ANISOU 957 O3' DA B 6 7779 3564 4970 -1025 -438 -1667 O ATOM 958 C2' DA B 6 -15.351 -23.662 -1.782 1.00 49.78 C ANISOU 958 C2' DA B 6 8623 4861 5431 -1422 -301 -1891 C ATOM 959 C1' DA B 6 -16.531 -24.569 -2.113 1.00 49.64 C ANISOU 959 C1' DA B 6 8582 4895 5385 -1428 -62 -2127 C ATOM 960 N9 DA B 6 -17.231 -25.069 -0.932 1.00 53.24 N ANISOU 960 N9 DA B 6 9019 5600 5609 -1656 36 -2249 N ATOM 961 C8 DA B 6 -16.734 -25.904 0.029 1.00 56.92 C ANISOU 961 C8 DA B 6 9495 6158 5972 -1862 95 -1947 C ATOM 962 N7 DA B 6 -17.593 -26.190 0.978 1.00 64.42 N ANISOU 962 N7 DA B 6 10429 7338 6710 -2037 186 -2155 N ATOM 963 C5 DA B 6 -18.734 -25.494 0.614 1.00 62.39 C ANISOU 963 C5 DA B 6 10035 7175 6493 -1838 173 -2505 C ATOM 964 C6 DA B 6 -20.007 -25.379 1.208 1.00 66.43 C ANISOU 964 C6 DA B 6 10386 7919 6936 -1781 222 -2705 C ATOM 965 N6 DA B 6 -20.348 -25.996 2.345 1.00 74.34 N ANISOU 965 N6 DA B 6 11415 9099 7734 -2021 338 -2723 N ATOM 966 N1 DA B 6 -20.920 -24.605 0.586 1.00 64.28 N ANISOU 966 N1 DA B 6 9956 7664 6804 -1478 136 -2852 N ATOM 967 C2 DA B 6 -20.576 -23.990 -0.552 1.00 58.41 C ANISOU 967 C2 DA B 6 9191 6755 6248 -1240 7 -2819 C ATOM 968 N3 DA B 6 -19.415 -24.021 -1.204 1.00 54.27 N ANISOU 968 N3 DA B 6 8761 6035 5825 -1247 -33 -2672 N ATOM 969 C4 DA B 6 -18.528 -24.798 -0.562 1.00 55.53 C ANISOU 969 C4 DA B 6 9108 6143 5848 -1557 61 -2508 C ATOM 970 P DA B 7 -13.741 -21.430 -3.282 1.00 61.16 P ANISOU 970 P DA B 7 9240 6400 7599 -742 1072 -233 P ATOM 971 OP1 DA B 7 -13.090 -20.739 -4.416 1.00 62.06 O ANISOU 971 OP1 DA B 7 9469 6484 7628 -657 1140 -207 O ATOM 972 OP2 DA B 7 -13.005 -21.595 -2.008 1.00 57.40 O ANISOU 972 OP2 DA B 7 8613 5913 7283 -737 1126 -128 O ATOM 973 O5' DA B 7 -15.127 -20.696 -2.975 1.00 57.14 O ANISOU 973 O5' DA B 7 8654 6031 7025 -792 880 -291 O ATOM 974 C5' DA B 7 -16.154 -20.696 -3.958 1.00 56.54 C ANISOU 974 C5' DA B 7 8684 5997 6802 -825 788 -397 C ATOM 975 C4' DA B 7 -17.442 -20.121 -3.399 1.00 52.31 C ANISOU 975 C4' DA B 7 8037 5597 6240 -872 617 -423 C ATOM 976 O4' DA B 7 -17.946 -20.981 -2.347 1.00 51.84 O ANISOU 976 O4' DA B 7 7870 5544 6281 -946 584 -428 O ATOM 977 C3' DA B 7 -17.317 -18.721 -2.795 1.00 44.89 C ANISOU 977 C3' DA B 7 6986 4742 5328 -813 570 -342 C ATOM 978 O3' DA B 7 -18.328 -17.876 -3.327 1.00 45.68 O ANISOU 978 O3' DA B 7 7100 4948 5310 -808 450 -379 O ATOM 979 C2' DA B 7 -17.495 -18.949 -1.289 1.00 41.32 C ANISOU 979 C2' DA B 7 6371 4327 5001 -846 536 -300 C ATOM 980 C1' DA B 7 -18.362 -20.198 -1.255 1.00 45.36 C ANISOU 980 C1' DA B 7 6893 4830 5513 -935 499 -372 C ATOM 981 N9 DA B 7 -18.199 -20.990 -0.039 1.00 44.10 N ANISOU 981 N9 DA B 7 6618 4651 5489 -965 534 -327 N ATOM 982 C8 DA B 7 -17.047 -21.569 0.417 1.00 42.65 C ANISOU 982 C8 DA B 7 6416 4376 5412 -941 667 -264 C ATOM 983 N7 DA B 7 -17.196 -22.233 1.538 1.00 41.73 N ANISOU 983 N7 DA B 7 6180 4274 5401 -969 672 -225 N ATOM 984 C5 DA B 7 -18.539 -22.082 1.839 1.00 41.86 C ANISOU 984 C5 DA B 7 6133 4393 5380 -1014 536 -264 C ATOM 985 C6 DA B 7 -19.332 -22.549 2.906 1.00 41.26 C ANISOU 985 C6 DA B 7 5922 4382 5374 -1051 480 -238 C ATOM 986 N6 DA B 7 -18.853 -23.296 3.906 1.00 41.06 N ANISOU 986 N6 DA B 7 5802 4328 5469 -1046 558 -169 N ATOM 987 N1 DA B 7 -20.640 -22.219 2.904 1.00 41.99 N ANISOU 987 N1 DA B 7 5972 4574 5406 -1085 347 -272 N ATOM 988 C2 DA B 7 -21.116 -21.473 1.901 1.00 42.98 C ANISOU 988 C2 DA B 7 6185 4737 5407 -1084 271 -330 C ATOM 989 N3 DA B 7 -20.470 -20.976 0.846 1.00 43.09 N ANISOU 989 N3 DA B 7 6329 4702 5341 -1049 312 -361 N ATOM 990 C4 DA B 7 -19.173 -21.320 0.876 1.00 43.59 C ANISOU 990 C4 DA B 7 6432 4661 5470 -1015 448 -325 C ATOM 991 P DT B 8 -18.339 -16.307 -2.988 1.00 50.97 P ANISOU 991 P DT B 8 7689 5696 5979 -739 399 -311 P ATOM 992 OP1 DT B 8 -18.962 -15.608 -4.135 1.00 52.10 O ANISOU 992 OP1 DT B 8 7916 5903 5976 -708 343 -340 O ATOM 993 OP2 DT B 8 -16.980 -15.925 -2.545 1.00 49.34 O ANISOU 993 OP2 DT B 8 7451 5414 5884 -684 506 -226 O ATOM 994 O5' DT B 8 -19.326 -16.202 -1.735 1.00 48.71 O ANISOU 994 O5' DT B 8 7255 5509 5745 -780 286 -307 O ATOM 995 C5' DT B 8 -20.628 -16.763 -1.823 1.00 51.32 C ANISOU 995 C5' DT B 8 7571 5912 6016 -849 183 -366 C ATOM 996 C4' DT B 8 -21.340 -16.704 -0.485 1.00 47.72 C ANISOU 996 C4' DT B 8 6962 5537 5633 -868 108 -334 C ATOM 997 O4' DT B 8 -20.802 -17.706 0.402 1.00 45.48 O ANISOU 997 O4' DT B 8 6621 5189 5470 -901 175 -316 O ATOM 998 C3' DT B 8 -21.217 -15.371 0.260 1.00 43.85 C ANISOU 998 C3' DT B 8 6389 5104 5168 -792 83 -272 C ATOM 999 O3' DT B 8 -22.490 -14.748 0.336 1.00 44.14 O ANISOU 999 O3' DT B 8 6375 5262 5137 -785 -31 -271 O ATOM 1000 C2' DT B 8 -20.684 -15.754 1.654 1.00 39.82 C ANISOU 1000 C2' DT B 8 5772 4574 4785 -792 120 -228 C ATOM 1001 C1' DT B 8 -20.958 -17.250 1.716 1.00 42.81 C ANISOU 1001 C1' DT B 8 6147 4918 5202 -871 140 -259 C ATOM 1002 N1 DT B 8 -20.016 -18.004 2.593 1.00 41.53 N ANISOU 1002 N1 DT B 8 5931 4687 5161 -875 232 -217 N ATOM 1003 C2 DT B 8 -20.507 -18.659 3.698 1.00 42.15 C ANISOU 1003 C2 DT B 8 5893 4811 5311 -901 210 -190 C ATOM 1004 O2 DT B 8 -21.685 -18.655 4.008 1.00 43.87 O ANISOU 1004 O2 DT B 8 6047 5119 5504 -921 118 -196 O ATOM 1005 N3 DT B 8 -19.564 -19.326 4.434 1.00 40.53 N ANISOU 1005 N3 DT B 8 5640 4547 5211 -895 304 -141 N ATOM 1006 C4 DT B 8 -18.207 -19.402 4.181 1.00 40.17 C ANISOU 1006 C4 DT B 8 5646 4405 5210 -870 414 -113 C ATOM 1007 O4 DT B 8 -17.438 -20.028 4.904 1.00 42.08 O ANISOU 1007 O4 DT B 8 5829 4610 5549 -864 494 -57 O ATOM 1008 C5 DT B 8 -17.757 -18.693 3.005 1.00 39.50 C ANISOU 1008 C5 DT B 8 5683 4273 5053 -844 434 -140 C ATOM 1009 C7 DT B 8 -16.305 -18.703 2.628 1.00 39.93 C ANISOU 1009 C7 DT B 8 5793 4224 5155 -809 558 -95 C ATOM 1010 C6 DT B 8 -18.673 -18.037 2.276 1.00 40.29 C ANISOU 1010 C6 DT B 8 5835 4430 5045 -846 344 -192 C ATOM 1011 P DG B 9 -22.617 -13.202 0.749 1.00 45.87 P ANISOU 1011 P DG B 9 6546 5541 5341 -697 -66 -222 P ATOM 1012 OP1 DG B 9 -23.784 -12.646 0.028 1.00 46.81 O ANISOU 1012 OP1 DG B 9 6679 5760 5346 -686 -152 -228 O ATOM 1013 OP2 DG B 9 -21.285 -12.576 0.594 1.00 44.22 O ANISOU 1013 OP2 DG B 9 6385 5238 5178 -646 23 -197 O ATOM 1014 O5' DG B 9 -22.959 -13.258 2.309 1.00 44.63 O ANISOU 1014 O5' DG B 9 6255 5437 5264 -690 -100 -189 O ATOM 1015 C5' DG B 9 -24.067 -14.025 2.757 1.00 47.22 C ANISOU 1015 C5' DG B 9 6507 5843 5592 -738 -165 -190 C ATOM 1016 C4' DG B 9 -24.049 -14.171 4.267 1.00 44.13 C ANISOU 1016 C4' DG B 9 5998 5483 5286 -714 -163 -149 C ATOM 1017 O4' DG B 9 -23.054 -15.152 4.653 1.00 41.95 O ANISOU 1017 O4' DG B 9 5718 5120 5102 -750 -81 -150 O ATOM 1018 C3' DG B 9 -23.712 -12.890 5.038 1.00 42.03 C ANISOU 1018 C3' DG B 9 5703 5239 5028 -624 -167 -119 C ATOM 1019 O3' DG B 9 -24.682 -12.670 6.049 1.00 42.76 O ANISOU 1019 O3' DG B 9 5696 5437 5115 -584 -226 -84 O ATOM 1020 C2' DG B 9 -22.332 -13.179 5.636 1.00 39.46 C ANISOU 1020 C2' DG B 9 5372 4826 4795 -624 -88 -112 C ATOM 1021 C1' DG B 9 -22.381 -14.687 5.794 1.00 40.15 C ANISOU 1021 C1' DG B 9 5427 4894 4934 -694 -56 -112 C ATOM 1022 N9 DG B 9 -21.066 -15.317 5.851 1.00 39.00 N ANISOU 1022 N9 DG B 9 5304 4647 4868 -715 40 -104 N ATOM 1023 C8 DG B 9 -19.987 -15.063 5.038 1.00 38.77 C ANISOU 1023 C8 DG B 9 5366 4521 4845 -711 107 -113 C ATOM 1024 N7 DG B 9 -18.939 -15.784 5.326 1.00 37.31 N ANISOU 1024 N7 DG B 9 5169 4262 4743 -727 194 -86 N ATOM 1025 C5 DG B 9 -19.349 -16.568 6.397 1.00 38.00 C ANISOU 1025 C5 DG B 9 5154 4402 4881 -742 183 -61 C ATOM 1026 C6 DG B 9 -18.642 -17.547 7.135 1.00 37.37 C ANISOU 1026 C6 DG B 9 5013 4290 4897 -756 258 -15 C ATOM 1027 O6 DG B 9 -17.473 -17.927 6.984 1.00 38.48 O ANISOU 1027 O6 DG B 9 5177 4346 5099 -759 352 14 O ATOM 1028 N1 DG B 9 -19.431 -18.103 8.140 1.00 39.27 N ANISOU 1028 N1 DG B 9 5146 4612 5162 -758 223 11 N ATOM 1029 C2 DG B 9 -20.736 -17.757 8.398 1.00 40.24 C ANISOU 1029 C2 DG B 9 5226 4836 5229 -747 129 -1 C ATOM 1030 N2 DG B 9 -21.334 -18.405 9.409 1.00 41.81 N ANISOU 1030 N2 DG B 9 5313 5104 5470 -741 118 45 N ATOM 1031 N3 DG B 9 -21.410 -16.844 7.713 1.00 39.70 N ANISOU 1031 N3 DG B 9 5213 4800 5072 -735 58 -41 N ATOM 1032 C4 DG B 9 -20.656 -16.292 6.731 1.00 39.11 C ANISOU 1032 C4 DG B 9 5244 4647 4969 -734 89 -71 C ATOM 1033 P DG B 10 -24.871 -11.208 6.686 1.00 52.73 P ANISOU 1033 P DG B 10 6942 6748 6346 -482 -257 -64 P ATOM 1034 OP1 DG B 10 -26.293 -10.841 6.523 1.00 59.29 O ANISOU 1034 OP1 DG B 10 7737 7688 7104 -453 -325 -34 O ATOM 1035 OP2 DG B 10 -23.818 -10.326 6.136 1.00 52.07 O ANISOU 1035 OP2 DG B 10 6945 6571 6269 -459 -216 -87 O ATOM 1036 O5' DG B 10 -24.570 -11.431 8.241 1.00 53.52 O ANISOU 1036 O5' DG B 10 6954 6874 6508 -446 -246 -42 O ATOM 1037 C5' DG B 10 -25.371 -12.335 8.991 1.00 56.29 C ANISOU 1037 C5' DG B 10 7205 7304 6876 -457 -264 -3 C ATOM 1038 C4' DG B 10 -24.597 -12.895 10.171 1.00 54.71 C ANISOU 1038 C4' DG B 10 6944 7095 6749 -446 -223 15 C ATOM 1039 O4' DG B 10 -23.479 -13.671 9.694 1.00 52.20 O ANISOU 1039 O4' DG B 10 6667 6673 6496 -516 -158 -5 O ATOM 1040 C3' DG B 10 -24.002 -11.845 11.115 1.00 54.26 C ANISOU 1040 C3' DG B 10 6888 7044 6683 -362 -230 6 C ATOM 1041 O3' DG B 10 -24.707 -11.844 12.351 1.00 57.65 O ANISOU 1041 O3' DG B 10 7231 7581 7094 -289 -255 46 O ATOM 1042 C2' DG B 10 -22.536 -12.276 11.301 1.00 51.44 C ANISOU 1042 C2' DG B 10 6542 6601 6403 -401 -173 -6 C ATOM 1043 C1' DG B 10 -22.499 -13.671 10.693 1.00 50.14 C ANISOU 1043 C1' DG B 10 6367 6396 6287 -486 -124 9 C ATOM 1044 N9 DG B 10 -21.210 -14.003 10.094 1.00 45.32 N ANISOU 1044 N9 DG B 10 5814 5672 5733 -537 -56 -5 N ATOM 1045 C8 DG B 10 -20.648 -13.441 8.973 1.00 44.77 C ANISOU 1045 C8 DG B 10 5845 5517 5649 -555 -37 -37 C ATOM 1046 N7 DG B 10 -19.476 -13.933 8.678 1.00 43.10 N ANISOU 1046 N7 DG B 10 5660 5215 5501 -590 38 -28 N ATOM 1047 C5 DG B 10 -19.245 -14.879 9.669 1.00 43.11 C ANISOU 1047 C5 DG B 10 5572 5244 5564 -598 69 13 C ATOM 1048 C6 DG B 10 -18.137 -15.736 9.874 1.00 41.31 C ANISOU 1048 C6 DG B 10 5320 4955 5422 -624 155 52 C ATOM 1049 O6 DG B 10 -17.105 -15.831 9.195 1.00 39.72 O ANISOU 1049 O6 DG B 10 5175 4657 5260 -647 224 60 O ATOM 1050 N1 DG B 10 -18.307 -16.540 10.998 1.00 41.45 N ANISOU 1050 N1 DG B 10 5231 5037 5480 -613 166 99 N ATOM 1051 C2 DG B 10 -19.409 -16.518 11.820 1.00 42.78 C ANISOU 1051 C2 DG B 10 5326 5317 5612 -577 104 109 C ATOM 1052 N2 DG B 10 -19.392 -17.368 12.858 1.00 43.52 N ANISOU 1052 N2 DG B 10 5316 5465 5756 -561 135 170 N ATOM 1053 N3 DG B 10 -20.453 -15.721 11.640 1.00 43.50 N ANISOU 1053 N3 DG B 10 5439 5465 5624 -550 26 75 N ATOM 1054 C4 DG B 10 -20.303 -14.932 10.550 1.00 44.20 C ANISOU 1054 C4 DG B 10 5631 5492 5673 -564 12 27 C ATOM 1055 P DG B 11 -24.271 -10.847 13.535 1.00 55.60 P ANISOU 1055 P DG B 11 6969 7347 6807 -193 -274 29 P ATOM 1056 OP1 DG B 11 -25.502 -10.462 14.260 1.00 57.81 O ANISOU 1056 OP1 DG B 11 7202 7743 7022 -98 -309 67 O ATOM 1057 OP2 DG B 11 -23.401 -9.794 12.966 1.00 52.86 O ANISOU 1057 OP2 DG B 11 6720 6902 6462 -200 -277 -30 O ATOM 1058 O5' DG B 11 -23.370 -11.759 14.493 1.00 55.01 O ANISOU 1058 O5' DG B 11 6827 7279 6797 -208 -237 51 O ATOM 1059 C5' DG B 11 -23.926 -12.924 15.094 1.00 54.50 C ANISOU 1059 C5' DG B 11 6659 7289 6759 -208 -214 118 C ATOM 1060 C4' DG B 11 -22.878 -13.671 15.899 1.00 51.41 C ANISOU 1060 C4' DG B 11 6211 6891 6429 -218 -170 143 C ATOM 1061 O4' DG B 11 -21.829 -14.140 15.013 1.00 47.65 O ANISOU 1061 O4' DG B 11 5783 6297 6024 -312 -121 123 O ATOM 1062 C3' DG B 11 -22.192 -12.844 16.986 1.00 52.73 C ANISOU 1062 C3' DG B 11 6380 7094 6559 -143 -200 118 C ATOM 1063 O3' DG B 11 -22.136 -13.582 18.199 1.00 56.69 O ANISOU 1063 O3' DG B 11 6779 7690 7070 -94 -179 180 O ATOM 1064 C2' DG B 11 -20.798 -12.575 16.419 1.00 48.39 C ANISOU 1064 C2' DG B 11 5892 6429 6064 -211 -184 74 C ATOM 1065 C1' DG B 11 -20.567 -13.790 15.533 1.00 46.09 C ANISOU 1065 C1' DG B 11 5590 6069 5851 -302 -113 109 C ATOM 1066 N9 DG B 11 -19.672 -13.520 14.410 1.00 42.74 N ANISOU 1066 N9 DG B 11 5253 5520 5466 -370 -87 73 N ATOM 1067 C8 DG B 11 -19.893 -12.648 13.373 1.00 42.47 C ANISOU 1067 C8 DG B 11 5314 5427 5397 -383 -111 23 C ATOM 1068 N7 DG B 11 -18.919 -12.610 12.507 1.00 40.28 N ANISOU 1068 N7 DG B 11 5096 5043 5168 -436 -69 12 N ATOM 1069 C5 DG B 11 -17.989 -13.515 13.002 1.00 40.15 C ANISOU 1069 C5 DG B 11 5019 5011 5225 -462 -12 58 C ATOM 1070 C6 DG B 11 -16.728 -13.896 12.488 1.00 38.91 C ANISOU 1070 C6 DG B 11 4881 4757 5145 -511 59 83 C ATOM 1071 O6 DG B 11 -16.165 -13.496 11.459 1.00 37.37 O ANISOU 1071 O6 DG B 11 4765 4467 4968 -539 88 68 O ATOM 1072 N1 DG B 11 -16.107 -14.843 13.298 1.00 39.14 N ANISOU 1072 N1 DG B 11 4823 4813 5236 -515 108 145 N ATOM 1073 C2 DG B 11 -16.637 -15.356 14.458 1.00 40.04 C ANISOU 1073 C2 DG B 11 4841 5036 5335 -474 90 178 C ATOM 1074 N2 DG B 11 -15.888 -16.262 15.104 1.00 38.78 N ANISOU 1074 N2 DG B 11 4599 4892 5242 -478 151 250 N ATOM 1075 N3 DG B 11 -17.819 -15.007 14.952 1.00 42.36 N ANISOU 1075 N3 DG B 11 5118 5422 5556 -425 25 156 N ATOM 1076 C4 DG B 11 -18.437 -14.085 14.174 1.00 42.05 C ANISOU 1076 C4 DG B 11 5164 5356 5459 -423 -23 95 C ATOM 1077 P DA B 12 -21.853 -12.830 19.590 1.00 62.10 P ANISOU 1077 P DA B 12 7449 8465 7682 13 -225 162 P ATOM 1078 OP1 DA B 12 -22.497 -13.612 20.668 1.00 63.77 O ANISOU 1078 OP1 DA B 12 7550 8807 7874 91 -200 249 O ATOM 1079 OP2 DA B 12 -22.187 -11.400 19.413 1.00 64.41 O ANISOU 1079 OP2 DA B 12 7839 8736 7897 59 -287 83 O ATOM 1080 O5' DA B 12 -20.272 -12.941 19.766 1.00 55.39 O ANISOU 1080 O5' DA B 12 6599 7558 6889 -41 -215 144 O ATOM 1081 C5' DA B 12 -19.657 -14.216 19.858 1.00 52.09 C ANISOU 1081 C5' DA B 12 6099 7136 6556 -89 -144 219 C ATOM 1082 C4' DA B 12 -18.149 -14.082 19.808 1.00 48.47 C ANISOU 1082 C4' DA B 12 5652 6610 6152 -143 -140 203 C ATOM 1083 O4' DA B 12 -17.732 -13.867 18.447 1.00 45.81 O ANISOU 1083 O4' DA B 12 5400 6134 5871 -231 -118 167 O ATOM 1084 C3' DA B 12 -17.594 -12.907 20.611 1.00 48.34 C ANISOU 1084 C3' DA B 12 5666 6628 6071 -96 -228 138 C ATOM 1085 O3' DA B 12 -16.942 -13.389 21.778 1.00 49.10 O ANISOU 1085 O3' DA B 12 5670 6821 6163 -59 -229 188 O ATOM 1086 C2' DA B 12 -16.616 -12.197 19.654 1.00 46.04 C ANISOU 1086 C2' DA B 12 5456 6197 5839 -181 -242 83 C ATOM 1087 C1' DA B 12 -16.540 -13.131 18.447 1.00 43.91 C ANISOU 1087 C1' DA B 12 5192 5836 5656 -259 -149 131 C ATOM 1088 N9 DA B 12 -16.446 -12.423 17.173 1.00 41.56 N ANISOU 1088 N9 DA B 12 4998 5416 5378 -312 -151 78 N ATOM 1089 C8 DA B 12 -17.363 -11.557 16.646 1.00 40.79 C ANISOU 1089 C8 DA B 12 4978 5301 5218 -288 -192 20 C ATOM 1090 N7 DA B 12 -17.022 -11.070 15.478 1.00 39.86 N ANISOU 1090 N7 DA B 12 4941 5072 5133 -338 -177 -7 N ATOM 1091 C5 DA B 12 -15.798 -11.660 15.215 1.00 39.13 C ANISOU 1091 C5 DA B 12 4824 4914 5131 -398 -119 37 C ATOM 1092 C6 DA B 12 -14.909 -11.555 14.127 1.00 37.20 C ANISOU 1092 C6 DA B 12 4631 4547 4955 -457 -69 47 C ATOM 1093 N6 DA B 12 -15.139 -10.782 13.061 1.00 36.17 N ANISOU 1093 N6 DA B 12 4593 4341 4811 -467 -72 9 N ATOM 1094 N1 DA B 12 -13.771 -12.278 14.178 1.00 36.28 N ANISOU 1094 N1 DA B 12 4465 4396 4924 -496 -6 112 N ATOM 1095 C2 DA B 12 -13.544 -13.051 15.248 1.00 36.50 C ANISOU 1095 C2 DA B 12 4394 4509 4965 -480 2 161 C ATOM 1096 N3 DA B 12 -14.303 -13.231 16.329 1.00 38.02 N ANISOU 1096 N3 DA B 12 4529 4823 5095 -424 -43 156 N ATOM 1097 C4 DA B 12 -15.427 -12.500 16.249 1.00 39.33 C ANISOU 1097 C4 DA B 12 4750 5017 5177 -384 -102 91 C ATOM 1098 P DG B 13 -16.285 -12.362 22.824 1.00 50.40 P ANISOU 1098 P DG B 13 5851 7044 6254 -13 -331 122 P ATOM 1099 OP1 DG B 13 -16.248 -13.027 24.142 1.00 53.64 O ANISOU 1099 OP1 DG B 13 6156 7608 6615 67 -327 190 O ATOM 1100 OP2 DG B 13 -16.966 -11.057 22.682 1.00 52.91 O ANISOU 1100 OP2 DG B 13 6279 7331 6493 26 -403 17 O ATOM 1101 O5' DG B 13 -14.785 -12.205 22.301 1.00 47.16 O ANISOU 1101 O5' DG B 13 5447 6528 5944 -117 -335 118 O ATOM 1102 C5' DG B 13 -14.023 -13.362 22.005 1.00 45.62 C ANISOU 1102 C5' DG B 13 5172 6310 5852 -174 -245 219 C ATOM 1103 C4' DG B 13 -12.830 -13.013 21.134 1.00 45.78 C ANISOU 1103 C4' DG B 13 5227 6198 5971 -271 -238 212 C ATOM 1104 O4' DG B 13 -13.286 -12.477 19.868 1.00 45.10 O ANISOU 1104 O4' DG B 13 5248 5986 5901 -310 -223 156 O ATOM 1105 C3' DG B 13 -11.881 -11.964 21.725 1.00 49.30 C ANISOU 1105 C3' DG B 13 5678 6648 6406 -287 -347 157 C ATOM 1106 O3' DG B 13 -10.585 -12.520 21.881 1.00 54.17 O ANISOU 1106 O3' DG B 13 6205 7266 7111 -338 -317 244 O ATOM 1107 C2' DG B 13 -11.891 -10.823 20.697 1.00 47.66 C ANISOU 1107 C2' DG B 13 5588 6297 6224 -336 -380 71 C ATOM 1108 C1' DG B 13 -12.345 -11.536 19.433 1.00 45.85 C ANISOU 1108 C1' DG B 13 5391 5984 6047 -366 -268 115 C ATOM 1109 N9 DG B 13 -12.971 -10.649 18.454 1.00 43.95 N ANISOU 1109 N9 DG B 13 5264 5648 5789 -375 -282 41 N ATOM 1110 C8 DG B 13 -14.145 -9.949 18.600 1.00 43.08 C ANISOU 1110 C8 DG B 13 5216 5570 5581 -314 -333 -32 C ATOM 1111 N7 DG B 13 -14.455 -9.232 17.553 1.00 40.64 N ANISOU 1111 N7 DG B 13 4999 5162 5281 -333 -329 -74 N ATOM 1112 C5 DG B 13 -13.421 -9.472 16.657 1.00 41.01 C ANISOU 1112 C5 DG B 13 5046 5102 5432 -410 -271 -29 C ATOM 1113 C6 DG B 13 -13.211 -8.969 15.349 1.00 40.22 C ANISOU 1113 C6 DG B 13 5024 4876 5381 -451 -235 -36 C ATOM 1114 O6 DG B 13 -13.921 -8.186 14.703 1.00 41.90 O ANISOU 1114 O6 DG B 13 5319 5047 5555 -431 -251 -85 O ATOM 1115 N1 DG B 13 -12.037 -9.467 14.788 1.00 39.53 N ANISOU 1115 N1 DG B 13 4909 4714 5398 -512 -167 34 N ATOM 1116 C2 DG B 13 -11.176 -10.338 15.411 1.00 39.14 C ANISOU 1116 C2 DG B 13 4764 4706 5402 -534 -137 106 C ATOM 1117 N2 DG B 13 -10.092 -10.706 14.712 1.00 40.03 N ANISOU 1117 N2 DG B 13 4860 4733 5616 -584 -60 182 N ATOM 1118 N3 DG B 13 -11.361 -10.816 16.635 1.00 41.43 N ANISOU 1118 N3 DG B 13 4976 5118 5648 -498 -173 116 N ATOM 1119 C4 DG B 13 -12.500 -10.342 17.196 1.00 41.19 C ANISOU 1119 C4 DG B 13 4976 5162 5512 -436 -240 43 C ATOM 1120 P DG B 14 -9.553 -11.874 22.926 1.00 56.49 P ANISOU 1120 P DG B 14 6445 7628 7389 -349 -435 224 P ATOM 1121 OP1 DG B 14 -8.843 -12.988 23.590 1.00 58.51 O ANISOU 1121 OP1 DG B 14 6564 7988 7679 -339 -382 353 O ATOM 1122 OP2 DG B 14 -10.296 -10.891 23.744 1.00 56.52 O ANISOU 1122 OP2 DG B 14 6514 7700 7261 -282 -552 103 O ATOM 1123 O5' DG B 14 -8.517 -11.082 21.998 1.00 54.69 O ANISOU 1123 O5' DG B 14 6260 7245 7275 -451 -456 207 O ATOM 1124 C5' DG B 14 -7.431 -11.781 21.402 1.00 53.86 C ANISOU 1124 C5' DG B 14 6084 7080 7299 -515 -367 327 C ATOM 1125 C4' DG B 14 -6.932 -11.078 20.152 1.00 50.84 C ANISOU 1125 C4' DG B 14 5776 6526 7016 -588 -347 312 C ATOM 1126 O4' DG B 14 -8.019 -10.856 19.233 1.00 47.21 O ANISOU 1126 O4' DG B 14 5432 5989 6517 -566 -304 246 O ATOM 1127 C3' DG B 14 -6.364 -9.690 20.357 1.00 51.41 C ANISOU 1127 C3' DG B 14 5880 6547 7109 -636 -480 229 C ATOM 1128 O3' DG B 14 -5.026 -9.760 20.818 1.00 52.87 O ANISOU 1128 O3' DG B 14 5954 6756 7377 -693 -518 308 O ATOM 1129 C2' DG B 14 -6.432 -9.112 18.941 1.00 49.75 C ANISOU 1129 C2' DG B 14 5768 6167 6969 -673 -425 211 C ATOM 1130 C1' DG B 14 -7.616 -9.856 18.314 1.00 45.83 C ANISOU 1130 C1' DG B 14 5331 5674 6409 -619 -322 209 C ATOM 1131 N9 DG B 14 -8.748 -8.986 18.015 1.00 43.78 N ANISOU 1131 N9 DG B 14 5186 5382 6068 -583 -366 95 N ATOM 1132 C8 DG B 14 -9.864 -8.777 18.787 1.00 43.08 C ANISOU 1132 C8 DG B 14 5126 5388 5853 -511 -426 16 C ATOM 1133 N7 DG B 14 -10.707 -7.932 18.262 1.00 42.83 N ANISOU 1133 N7 DG B 14 5197 5299 5776 -487 -447 -64 N ATOM 1134 C5 DG B 14 -10.108 -7.552 17.067 1.00 42.73 C ANISOU 1134 C5 DG B 14 5226 5146 5863 -546 -400 -39 C ATOM 1135 C6 DG B 14 -10.553 -6.654 16.067 1.00 40.04 C ANISOU 1135 C6 DG B 14 4987 4698 5528 -546 -391 -86 C ATOM 1136 O6 DG B 14 -11.601 -5.994 16.039 1.00 40.02 O ANISOU 1136 O6 DG B 14 5059 4702 5444 -493 -424 -160 O ATOM 1137 N1 DG B 14 -9.640 -6.556 15.019 1.00 38.67 N ANISOU 1137 N1 DG B 14 4820 4404 5470 -604 -329 -23 N ATOM 1138 C2 DG B 14 -8.450 -7.239 14.945 1.00 41.06 C ANISOU 1138 C2 DG B 14 5040 4688 5871 -656 -278 76 C ATOM 1139 N2 DG B 14 -7.701 -7.015 13.855 1.00 41.55 N ANISOU 1139 N2 DG B 14 5122 4629 6036 -695 -210 138 N ATOM 1140 N3 DG B 14 -8.022 -8.083 15.875 1.00 42.01 N ANISOU 1140 N3 DG B 14 5063 4908 5992 -659 -285 123 N ATOM 1141 C4 DG B 14 -8.900 -8.189 16.903 1.00 42.66 C ANISOU 1141 C4 DG B 14 5138 5111 5960 -604 -349 59 C ATOM 1142 P DG B 15 -4.301 -8.435 21.368 1.00 50.21 P ANISOU 1142 P DG B 15 5617 6394 7065 -755 -686 227 P ATOM 1143 OP1 DG B 15 -3.043 -8.840 22.032 1.00 50.80 O ANISOU 1143 OP1 DG B 15 5548 6547 7208 -804 -723 332 O ATOM 1144 OP2 DG B 15 -5.318 -7.668 22.118 1.00 51.47 O ANISOU 1144 OP2 DG B 15 5866 6607 7082 -697 -795 71 O ATOM 1145 O5' DG B 15 -3.925 -7.611 20.047 1.00 51.15 O ANISOU 1145 O5' DG B 15 5808 6318 7310 -822 -653 224 O ATOM 1146 C5' DG B 15 -2.983 -8.129 19.110 1.00 51.09 C ANISOU 1146 C5' DG B 15 5743 6226 7444 -870 -537 368 C ATOM 1147 C4' DG B 15 -3.026 -7.331 17.817 1.00 51.69 C ANISOU 1147 C4' DG B 15 5916 6127 7597 -897 -492 348 C ATOM 1148 O4' DG B 15 -4.404 -7.166 17.416 1.00 48.62 O ANISOU 1148 O4' DG B 15 5652 5724 7097 -832 -466 247 O ATOM 1149 C3' DG B 15 -2.422 -5.929 17.914 1.00 58.76 C ANISOU 1149 C3' DG B 15 6823 6930 8573 -969 -619 287 C ATOM 1150 O3' DG B 15 -1.250 -5.833 17.107 1.00 65.21 O ANISOU 1150 O3' DG B 15 7580 7638 9560 -1035 -560 415 O ATOM 1151 C2' DG B 15 -3.519 -4.975 17.426 1.00 55.87 C ANISOU 1151 C2' DG B 15 6606 6481 8142 -932 -639 154 C ATOM 1152 C1' DG B 15 -4.613 -5.885 16.878 1.00 49.37 C ANISOU 1152 C1' DG B 15 5840 5699 7218 -851 -516 163 C ATOM 1153 N9 DG B 15 -5.947 -5.442 17.267 1.00 45.70 N ANISOU 1153 N9 DG B 15 5473 5280 6612 -784 -571 30 N ATOM 1154 C8 DG B 15 -6.608 -5.742 18.434 1.00 44.21 C ANISOU 1154 C8 DG B 15 5270 5233 6295 -729 -636 -33 C ATOM 1155 N7 DG B 15 -7.788 -5.194 18.519 1.00 42.73 N ANISOU 1155 N7 DG B 15 5181 5055 6001 -666 -665 -138 N ATOM 1156 C5 DG B 15 -7.915 -4.477 17.337 1.00 42.75 C ANISOU 1156 C5 DG B 15 5265 4914 6065 -683 -620 -147 C ATOM 1157 C6 DG B 15 -8.983 -3.678 16.868 1.00 42.08 C ANISOU 1157 C6 DG B 15 5294 4778 5917 -632 -620 -228 C ATOM 1158 O6 DG B 15 -10.064 -3.438 17.424 1.00 40.66 O ANISOU 1158 O6 DG B 15 5168 4667 5615 -558 -659 -309 O ATOM 1159 N1 DG B 15 -8.706 -3.128 15.618 1.00 41.09 N ANISOU 1159 N1 DG B 15 5215 4511 5887 -663 -561 -194 N ATOM 1160 C2 DG B 15 -7.543 -3.326 14.912 1.00 43.24 C ANISOU 1160 C2 DG B 15 5434 4699 6297 -731 -504 -92 C ATOM 1161 N2 DG B 15 -7.459 -2.712 13.722 1.00 43.58 N ANISOU 1161 N2 DG B 15 5534 4615 6411 -739 -443 -63 N ATOM 1162 N3 DG B 15 -6.533 -4.074 15.340 1.00 44.50 N ANISOU 1162 N3 DG B 15 5486 4902 6520 -779 -500 -11 N ATOM 1163 C4 DG B 15 -6.788 -4.616 16.557 1.00 44.47 C ANISOU 1163 C4 DG B 15 5434 5039 6425 -754 -562 -46 C ATOM 1164 P DT B 16 -0.276 -4.560 17.249 1.00 67.86 P ANISOU 1164 P DT B 16 7877 7875 10031 -1133 -686 401 P ATOM 1165 OP1 DT B 16 1.029 -4.924 16.659 1.00 70.87 O ANISOU 1165 OP1 DT B 16 8144 8202 10582 -1188 -606 585 O ATOM 1166 OP2 DT B 16 -0.344 -4.094 18.650 1.00 71.78 O ANISOU 1166 OP2 DT B 16 8353 8471 10449 -1156 -867 282 O ATOM 1167 O5' DT B 16 -0.960 -3.439 16.333 1.00 67.64 O ANISOU 1167 O5' DT B 16 7991 7695 10016 -1120 -674 309 O ATOM 1168 C5' DT B 16 -1.138 -3.670 14.941 1.00 64.33 C ANISOU 1168 C5' DT B 16 7627 7180 9636 -1083 -516 387 C ATOM 1169 C4' DT B 16 -1.779 -2.467 14.271 1.00 65.15 C ANISOU 1169 C4' DT B 16 7852 7157 9745 -1068 -530 295 C ATOM 1170 O4' DT B 16 -3.170 -2.369 14.669 1.00 59.98 O ANISOU 1170 O4' DT B 16 7302 6570 8917 -996 -567 152 O ATOM 1171 C3' DT B 16 -1.135 -1.118 14.608 1.00 73.53 C ANISOU 1171 C3' DT B 16 8898 8113 10928 -1151 -660 246 C ATOM 1172 O3' DT B 16 -0.796 -0.426 13.411 1.00 80.31 O ANISOU 1172 O3' DT B 16 9784 8811 11918 -1164 -582 317 O ATOM 1173 C2' DT B 16 -2.214 -0.377 15.407 1.00 71.02 C ANISOU 1173 C2' DT B 16 8684 7825 10475 -1116 -777 55 C ATOM 1174 C1' DT B 16 -3.492 -1.021 14.895 1.00 62.40 C ANISOU 1174 C1' DT B 16 7683 6795 9232 -1010 -669 32 C ATOM 1175 N1 DT B 16 -4.620 -0.963 15.870 1.00 57.85 N ANISOU 1175 N1 DT B 16 7172 6326 8482 -947 -750 -111 N ATOM 1176 C2 DT B 16 -5.768 -0.285 15.534 1.00 54.95 C ANISOU 1176 C2 DT B 16 6928 5919 8032 -880 -739 -204 C ATOM 1177 O2 DT B 16 -5.922 0.280 14.466 1.00 54.27 O ANISOU 1177 O2 DT B 16 6899 5717 8005 -870 -670 -178 O ATOM 1178 N3 DT B 16 -6.741 -0.293 16.499 1.00 53.22 N ANISOU 1178 N3 DT B 16 6757 5808 7656 -815 -807 -318 N ATOM 1179 C4 DT B 16 -6.680 -0.897 17.741 1.00 52.71 C ANISOU 1179 C4 DT B 16 6634 5888 7506 -807 -882 -349 C ATOM 1180 O4 DT B 16 -7.609 -0.848 18.542 1.00 50.75 O ANISOU 1180 O4 DT B 16 6437 5733 7114 -734 -930 -443 O ATOM 1181 C5 DT B 16 -5.447 -1.590 18.031 1.00 54.84 C ANISOU 1181 C5 DT B 16 6774 6197 7865 -882 -893 -249 C ATOM 1182 C7 DT B 16 -5.264 -2.283 19.348 1.00 54.66 C ANISOU 1182 C7 DT B 16 6671 6340 7756 -873 -969 -261 C ATOM 1183 C6 DT B 16 -4.488 -1.588 17.093 1.00 56.73 C ANISOU 1183 C6 DT B 16 6963 6329 8264 -949 -827 -135 C ATOM 1184 P DT B 17 0.013 0.961 13.479 1.00 91.88 P ANISOU 1184 P DT B 17 11222 10127 13562 -1258 -685 305 P ATOM 1185 OP1 DT B 17 0.887 1.027 12.288 1.00 94.33 O ANISOU 1185 OP1 DT B 17 11478 10318 14044 -1277 -562 480 O ATOM 1186 OP2 DT B 17 0.604 1.076 14.831 1.00 95.35 O ANISOU 1186 OP2 DT B 17 11579 10636 14016 -1341 -855 246 O ATOM 1187 O5' DT B 17 -1.130 2.072 13.348 1.00 94.68 O ANISOU 1187 O5' DT B 17 11727 10403 13844 -1210 -721 149 O ATOM 1188 C5' DT B 17 -0.880 3.407 13.767 1.00102.38 C ANISOU 1188 C5' DT B 17 12725 11257 14917 -1278 -847 57 C ATOM 1189 C4' DT B 17 -2.147 4.237 13.679 1.00102.50 C ANISOU 1189 C4' DT B 17 12893 11226 14827 -1201 -854 -85 C ATOM 1190 O4' DT B 17 -3.287 3.399 13.981 1.00 95.93 O ANISOU 1190 O4' DT B 17 12121 10550 13779 -1103 -821 -147 O ATOM 1191 C3' DT B 17 -2.226 5.389 14.665 1.00109.06 C ANISOU 1191 C3' DT B 17 13778 11990 15671 -1250 -1017 -250 C ATOM 1192 O3' DT B 17 -1.617 6.547 14.110 1.00115.84 O ANISOU 1192 O3' DT B 17 14636 12649 16731 -1316 -1026 -221 O ATOM 1193 C2' DT B 17 -3.732 5.574 14.833 1.00106.06 C ANISOU 1193 C2' DT B 17 13539 11661 15096 -1132 -1000 -380 C ATOM 1194 C1' DT B 17 -4.263 4.144 14.687 1.00 97.56 C ANISOU 1194 C1' DT B 17 12436 10761 13870 -1057 -907 -316 C ATOM 1195 N1 DT B 17 -4.538 3.462 15.990 1.00 95.27 N ANISOU 1195 N1 DT B 17 12126 10642 13431 -1041 -1000 -399 N ATOM 1196 C2 DT B 17 -5.821 3.451 16.484 1.00 92.18 C ANISOU 1196 C2 DT B 17 11830 10337 12855 -941 -1011 -511 C ATOM 1197 O2 DT B 17 -6.759 3.976 15.913 1.00 91.31 O ANISOU 1197 O2 DT B 17 11821 10175 12699 -868 -952 -545 O ATOM 1198 N3 DT B 17 -5.969 2.800 17.680 1.00 91.02 N ANISOU 1198 N3 DT B 17 11653 10350 12582 -923 -1090 -567 N ATOM 1199 C4 DT B 17 -4.982 2.171 18.416 1.00 92.21 C ANISOU 1199 C4 DT B 17 11685 10585 12765 -994 -1159 -525 C ATOM 1200 O4 DT B 17 -5.215 1.612 19.483 1.00 91.58 O ANISOU 1200 O4 DT B 17 11583 10658 12556 -961 -1223 -574 O ATOM 1201 C5 DT B 17 -3.658 2.217 17.842 1.00 94.98 C ANISOU 1201 C5 DT B 17 11935 10840 13312 -1102 -1147 -406 C ATOM 1202 C7 DT B 17 -2.506 1.569 18.549 1.00 96.77 C ANISOU 1202 C7 DT B 17 12018 11155 13595 -1184 -1218 -335 C ATOM 1203 C6 DT B 17 -3.502 2.851 16.670 1.00 96.30 C ANISOU 1203 C6 DT B 17 12133 10845 13610 -1120 -1067 -348 C TER 1204 DT B 17 ATOM 1205 O5' DT C 2 -12.267 7.250 26.809 1.00127.98 O ANISOU 1205 O5' DT C 2 17194 16232 15199 -210 -1453 -252 O ATOM 1206 C5' DT C 2 -13.098 6.287 26.171 1.00123.46 C ANISOU 1206 C5' DT C 2 16421 15904 14585 -197 -1416 -315 C ATOM 1207 C4' DT C 2 -13.171 6.545 24.677 1.00118.32 C ANISOU 1207 C4' DT C 2 15775 15253 13930 5 -1282 -378 C ATOM 1208 O4' DT C 2 -11.839 6.632 24.140 1.00114.14 O ANISOU 1208 O4' DT C 2 15302 14389 13679 -57 -1266 -309 O ATOM 1209 C3' DT C 2 -13.876 5.453 23.870 1.00111.51 C ANISOU 1209 C3' DT C 2 14698 14604 13067 1 -1244 -436 C ATOM 1210 O3' DT C 2 -15.155 5.909 23.442 1.00113.07 O ANISOU 1210 O3' DT C 2 14902 15096 12964 235 -1164 -540 O ATOM 1211 C2' DT C 2 -12.942 5.178 22.676 1.00104.40 C ANISOU 1211 C2' DT C 2 13773 13476 12417 -5 -1176 -415 C ATOM 1212 C1' DT C 2 -11.875 6.263 22.790 1.00107.53 C ANISOU 1212 C1' DT C 2 14380 13567 12909 36 -1166 -355 C ATOM 1213 N1 DT C 2 -10.514 5.798 22.395 1.00102.27 N ANISOU 1213 N1 DT C 2 13689 12582 12588 -119 -1177 -269 N ATOM 1214 C2 DT C 2 -9.934 6.302 21.255 1.00 99.72 C ANISOU 1214 C2 DT C 2 13447 12088 12355 18 -1072 -278 C ATOM 1215 O2 DT C 2 -10.476 7.122 20.535 1.00101.61 O ANISOU 1215 O2 DT C 2 13779 12424 12404 261 -971 -354 O ATOM 1216 N3 DT C 2 -8.684 5.810 20.984 1.00 94.98 N ANISOU 1216 N3 DT C 2 12813 11196 12080 -142 -1087 -191 N ATOM 1217 C4 DT C 2 -7.973 4.883 21.724 1.00 92.54 C ANISOU 1217 C4 DT C 2 12399 10752 12012 -419 -1197 -97 C ATOM 1218 O4 DT C 2 -6.853 4.502 21.397 1.00 88.41 O ANISOU 1218 O4 DT C 2 11850 9964 11779 -543 -1199 -20 O ATOM 1219 C5 DT C 2 -8.640 4.394 22.907 1.00 95.46 C ANISOU 1219 C5 DT C 2 12688 11313 12269 -552 -1307 -94 C ATOM 1220 C7 DT C 2 -7.968 3.385 23.790 1.00 93.90 C ANISOU 1220 C7 DT C 2 12373 10995 12311 -854 -1434 5 C ATOM 1221 C6 DT C 2 -9.864 4.870 23.182 1.00100.35 C ANISOU 1221 C6 DT C 2 13341 12219 12569 -397 -1291 -180 C ATOM 1222 P DA C 3 -16.264 4.858 22.942 1.00103.62 P ANISOU 1222 P DA C 3 13488 14212 11673 240 -1145 -609 P ATOM 1223 OP1 DA C 3 -17.583 5.524 23.026 1.00110.81 O ANISOU 1223 OP1 DA C 3 14438 15420 12243 455 -1097 -694 O ATOM 1224 OP2 DA C 3 -16.035 3.586 23.660 1.00101.80 O ANISOU 1224 OP2 DA C 3 13086 13980 11614 -41 -1258 -550 O ATOM 1225 O5' DA C 3 -15.902 4.623 21.402 1.00 91.84 O ANISOU 1225 O5' DA C 3 11954 12628 10314 326 -1041 -639 O ATOM 1226 C5' DA C 3 -15.872 5.726 20.508 1.00 89.55 C ANISOU 1226 C5' DA C 3 11817 12280 9926 574 -927 -685 C ATOM 1227 C4' DA C 3 -15.184 5.355 19.206 1.00 79.30 C ANISOU 1227 C4' DA C 3 10480 10816 8834 585 -850 -684 C ATOM 1228 O4' DA C 3 -13.783 5.056 19.455 1.00 73.09 O ANISOU 1228 O4' DA C 3 9712 9698 8360 387 -902 -585 O ATOM 1229 C3' DA C 3 -15.757 4.127 18.490 1.00 73.73 C ANISOU 1229 C3' DA C 3 9563 10292 8160 531 -834 -728 C ATOM 1230 O3' DA C 3 -15.836 4.388 17.099 1.00 72.03 O ANISOU 1230 O3' DA C 3 9373 10073 7924 712 -714 -786 O ATOM 1231 C2' DA C 3 -14.722 3.045 18.787 1.00 67.22 C ANISOU 1231 C2' DA C 3 8628 9254 7659 250 -913 -640 C ATOM 1232 C1' DA C 3 -13.449 3.869 18.778 1.00 66.11 C ANISOU 1232 C1' DA C 3 8661 8770 7688 254 -896 -572 C ATOM 1233 N9 DA C 3 -12.325 3.233 19.458 1.00 62.60 N ANISOU 1233 N9 DA C 3 8174 8076 7534 -10 -991 -465 N ATOM 1234 C8 DA C 3 -12.360 2.507 20.616 1.00 63.50 C ANISOU 1234 C8 DA C 3 8190 8237 7701 -229 -1114 -414 C ATOM 1235 N7 DA C 3 -11.187 2.053 20.991 1.00 60.60 N ANISOU 1235 N7 DA C 3 7804 7599 7622 -441 -1180 -314 N ATOM 1236 C5 DA C 3 -10.324 2.511 20.010 1.00 57.55 C ANISOU 1236 C5 DA C 3 7510 6974 7384 -353 -1090 -299 C ATOM 1237 C6 DA C 3 -8.934 2.369 19.824 1.00 54.48 C ANISOU 1237 C6 DA C 3 7148 6244 7309 -481 -1097 -206 C ATOM 1238 N6 DA C 3 -8.144 1.693 20.665 1.00 53.95 N ANISOU 1238 N6 DA C 3 7014 6013 7472 -738 -1205 -106 N ATOM 1239 N1 DA C 3 -8.385 2.953 18.738 1.00 51.53 N ANISOU 1239 N1 DA C 3 6870 5702 7005 -334 -987 -216 N ATOM 1240 C2 DA C 3 -9.179 3.630 17.900 1.00 52.09 C ANISOU 1240 C2 DA C 3 7008 5938 6845 -78 -881 -315 C ATOM 1241 N3 DA C 3 -10.493 3.831 17.968 1.00 54.80 N ANISOU 1241 N3 DA C 3 7333 6600 6888 62 -865 -407 N ATOM 1242 C4 DA C 3 -11.009 3.240 19.057 1.00 57.77 C ANISOU 1242 C4 DA C 3 7612 7136 7204 -88 -973 -393 C ATOM 1243 P DA C 4 -17.009 3.744 16.211 1.00 75.16 P ANISOU 1243 P DA C 4 9619 10772 8166 809 -659 -877 P ATOM 1244 OP1 DA C 4 -18.242 4.522 16.458 1.00 81.60 O ANISOU 1244 OP1 DA C 4 10488 11866 8649 1010 -634 -946 O ATOM 1245 OP2 DA C 4 -17.001 2.281 16.436 1.00 70.41 O ANISOU 1245 OP2 DA C 4 8810 10221 7719 573 -734 -850 O ATOM 1246 O5' DA C 4 -16.523 4.009 14.712 1.00 69.76 O ANISOU 1246 O5' DA C 4 8991 9942 7571 948 -536 -907 O ATOM 1247 C5' DA C 4 -15.948 5.263 14.367 1.00 69.24 C ANISOU 1247 C5' DA C 4 9128 9687 7493 1114 -465 -901 C ATOM 1248 C4' DA C 4 -14.702 5.072 13.520 1.00 62.80 C ANISOU 1248 C4' DA C 4 8340 8562 6960 1058 -414 -856 C ATOM 1249 O4' DA C 4 -13.627 4.548 14.343 1.00 57.68 O ANISOU 1249 O4' DA C 4 7664 7676 6577 808 -506 -755 O ATOM 1250 C3' DA C 4 -14.861 4.102 12.351 1.00 58.12 C ANISOU 1250 C3' DA C 4 7606 8027 6450 1043 -355 -897 C ATOM 1251 O3' DA C 4 -14.223 4.627 11.199 1.00 58.44 O ANISOU 1251 O3' DA C 4 7750 7878 6576 1174 -245 -907 O ATOM 1252 C2' DA C 4 -14.175 2.829 12.846 1.00 52.21 C ANISOU 1252 C2' DA C 4 6709 7157 5972 753 -444 -823 C ATOM 1253 C1' DA C 4 -13.084 3.390 13.746 1.00 51.19 C ANISOU 1253 C1' DA C 4 6701 6751 5998 652 -502 -730 C ATOM 1254 N9 DA C 4 -12.682 2.475 14.811 1.00 48.34 N ANISOU 1254 N9 DA C 4 6226 6333 5806 381 -625 -653 N ATOM 1255 C8 DA C 4 -13.490 1.907 15.756 1.00 50.03 C ANISOU 1255 C8 DA C 4 6328 6778 5903 277 -719 -662 C ATOM 1256 N7 DA C 4 -12.855 1.125 16.596 1.00 46.93 N ANISOU 1256 N7 DA C 4 5850 6264 5715 25 -822 -580 N ATOM 1257 C5 DA C 4 -11.537 1.185 16.177 1.00 43.82 C ANISOU 1257 C5 DA C 4 5517 5538 5596 -39 -793 -511 C ATOM 1258 C6 DA C 4 -10.360 0.576 16.655 1.00 40.97 C ANISOU 1258 C6 DA C 4 5112 4910 5544 -277 -863 -406 C ATOM 1259 N6 DA C 4 -10.333 -0.248 17.708 1.00 36.07 N ANISOU 1259 N6 DA C 4 4377 4323 5007 -505 -984 -352 N ATOM 1260 N1 DA C 4 -9.208 0.847 16.006 1.00 37.50 N ANISOU 1260 N1 DA C 4 4752 4168 5327 -273 -804 -355 N ATOM 1261 C2 DA C 4 -9.240 1.672 14.952 1.00 38.02 C ANISOU 1261 C2 DA C 4 4935 4203 5308 -45 -683 -409 C ATOM 1262 N3 DA C 4 -10.282 2.303 14.412 1.00 41.47 N ANISOU 1262 N3 DA C 4 5425 4871 5461 189 -610 -509 N ATOM 1263 C4 DA C 4 -11.412 2.014 15.077 1.00 44.31 C ANISOU 1263 C4 DA C 4 5700 5527 5607 179 -671 -556 C ATOM 1264 P DC C 5 -14.551 4.019 9.750 1.00 59.58 P ANISOU 1264 P DC C 5 7806 8104 6729 1251 -150 -972 P ATOM 1265 OP1 DC C 5 -14.318 5.091 8.757 1.00 64.57 O ANISOU 1265 OP1 DC C 5 8600 8632 7303 1479 -32 -1006 O ATOM 1266 OP2 DC C 5 -15.875 3.361 9.827 1.00 61.89 O ANISOU 1266 OP2 DC C 5 7951 8744 6820 1258 -180 -1039 O ATOM 1267 O5' DC C 5 -13.446 2.880 9.559 1.00 50.47 O ANISOU 1267 O5' DC C 5 6546 6710 5921 1013 -173 -902 O ATOM 1268 C5' DC C 5 -12.070 3.210 9.676 1.00 49.86 C ANISOU 1268 C5' DC C 5 6567 6284 6093 935 -170 -816 C ATOM 1269 C4' DC C 5 -11.218 1.958 9.779 1.00 47.11 C ANISOU 1269 C4' DC C 5 6082 5764 6055 677 -218 -745 C ATOM 1270 O4' DC C 5 -11.231 1.464 11.128 1.00 45.51 O ANISOU 1270 O4' DC C 5 5799 5598 5893 476 -350 -689 O ATOM 1271 C3' DC C 5 -11.680 0.784 8.914 1.00 47.15 C ANISOU 1271 C3' DC C 5 5921 5903 6090 630 -183 -796 C ATOM 1272 O3' DC C 5 -10.850 0.679 7.765 1.00 47.84 O ANISOU 1272 O3' DC C 5 6041 5769 6367 659 -83 -787 O ATOM 1273 C2' DC C 5 -11.546 -0.450 9.832 1.00 41.98 C ANISOU 1273 C2' DC C 5 5096 5265 5591 355 -302 -740 C ATOM 1274 C1' DC C 5 -10.873 0.112 11.083 1.00 41.17 C ANISOU 1274 C1' DC C 5 5080 4999 5563 258 -390 -653 C ATOM 1275 N1 DC C 5 -11.305 -0.544 12.353 1.00 38.04 N ANISOU 1275 N1 DC C 5 4567 4747 5138 76 -523 -624 N ATOM 1276 C2 DC C 5 -10.349 -1.154 13.172 1.00 36.69 C ANISOU 1276 C2 DC C 5 4342 4370 5230 -172 -615 -522 C ATOM 1277 O2 DC C 5 -9.161 -1.137 12.827 1.00 34.92 O ANISOU 1277 O2 DC C 5 4164 3845 5259 -233 -583 -455 O ATOM 1278 N3 DC C 5 -10.752 -1.746 14.325 1.00 36.30 N ANISOU 1278 N3 DC C 5 4188 4455 5149 -338 -735 -496 N ATOM 1279 C4 DC C 5 -12.043 -1.742 14.661 1.00 38.78 C ANISOU 1279 C4 DC C 5 4453 5095 5187 -263 -763 -568 C ATOM 1280 N4 DC C 5 -12.392 -2.339 15.806 1.00 40.15 N ANISOU 1280 N4 DC C 5 4524 5389 5341 -433 -881 -538 N ATOM 1281 C5 DC C 5 -13.033 -1.126 13.838 1.00 40.13 C ANISOU 1281 C5 DC C 5 4675 5481 5092 -10 -670 -670 C ATOM 1282 C6 DC C 5 -12.623 -0.545 12.705 1.00 39.87 C ANISOU 1282 C6 DC C 5 4746 5312 5091 150 -554 -695 C ATOM 1283 P DC C 6 -11.176 -0.402 6.622 1.00 52.81 P ANISOU 1283 P DC C 6 6535 6488 7041 640 -20 -843 P ATOM 1284 OP1 DC C 6 -10.645 0.126 5.346 1.00 55.82 O ANISOU 1284 OP1 DC C 6 7028 6701 7479 794 112 -863 O ATOM 1285 OP2 DC C 6 -12.606 -0.766 6.731 1.00 57.53 O ANISOU 1285 OP2 DC C 6 7031 7452 7377 688 -54 -924 O ATOM 1286 O5' DC C 6 -10.311 -1.676 7.048 1.00 46.47 O ANISOU 1286 O5' DC C 6 5591 5510 6554 351 -89 -758 O ATOM 1287 C5' DC C 6 -8.915 -1.536 7.273 1.00 45.18 C ANISOU 1287 C5' DC C 6 5491 5002 6675 241 -93 -658 C ATOM 1288 C4' DC C 6 -8.331 -2.814 7.844 1.00 41.62 C ANISOU 1288 C4' DC C 6 4882 4447 6485 -39 -177 -583 C ATOM 1289 O4' DC C 6 -8.738 -2.959 9.227 1.00 39.43 O ANISOU 1289 O4' DC C 6 4549 4300 6134 -165 -311 -553 O ATOM 1290 C3' DC C 6 -8.765 -4.098 7.127 1.00 42.03 C ANISOU 1290 C3' DC C 6 4768 4623 6579 -117 -153 -630 C ATOM 1291 O3' DC C 6 -7.619 -4.825 6.695 1.00 38.86 O ANISOU 1291 O3' DC C 6 4320 3944 6502 -263 -121 -563 O ATOM 1292 C2' DC C 6 -9.562 -4.867 8.187 1.00 39.42 C ANISOU 1292 C2' DC C 6 4291 4530 6159 -268 -282 -633 C ATOM 1293 C1' DC C 6 -9.000 -4.314 9.483 1.00 36.86 C ANISOU 1293 C1' DC C 6 4032 4077 5896 -360 -378 -547 C ATOM 1294 N1 DC C 6 -9.957 -4.411 10.620 1.00 38.11 N ANISOU 1294 N1 DC C 6 4126 4497 5857 -412 -491 -563 N ATOM 1295 C2 DC C 6 -9.537 -4.962 11.835 1.00 34.70 C ANISOU 1295 C2 DC C 6 3618 3997 5571 -643 -616 -479 C ATOM 1296 O2 DC C 6 -8.367 -5.347 11.950 1.00 32.70 O ANISOU 1296 O2 DC C 6 3349 3463 5612 -802 -632 -389 O ATOM 1297 N3 DC C 6 -10.424 -5.051 12.856 1.00 35.06 N ANISOU 1297 N3 DC C 6 3607 4284 5431 -687 -715 -496 N ATOM 1298 C4 DC C 6 -11.677 -4.623 12.691 1.00 38.33 C ANISOU 1298 C4 DC C 6 4035 4996 5533 -509 -691 -590 C ATOM 1299 N4 DC C 6 -12.517 -4.732 13.726 1.00 41.35 N ANISOU 1299 N4 DC C 6 4360 5608 5744 -559 -787 -600 N ATOM 1300 C5 DC C 6 -12.125 -4.065 11.458 1.00 41.77 C ANISOU 1300 C5 DC C 6 4545 5506 5819 -273 -566 -674 C ATOM 1301 C6 DC C 6 -11.241 -3.982 10.459 1.00 41.10 C ANISOU 1301 C6 DC C 6 4519 5181 5916 -234 -471 -659 C ATOM 1302 P DC C 7 -7.769 -6.281 6.029 1.00 43.99 P ANISOU 1302 P DC C 7 6230 4852 5632 568 555 -491 P ATOM 1303 OP1 DC C 7 -6.738 -6.379 4.974 1.00 43.68 O ANISOU 1303 OP1 DC C 7 6332 4710 5557 729 615 -481 O ATOM 1304 OP2 DC C 7 -9.187 -6.515 5.673 1.00 43.49 O ANISOU 1304 OP2 DC C 7 6208 4728 5587 549 432 -568 O ATOM 1305 O5' DC C 7 -7.372 -7.277 7.215 1.00 45.12 O ANISOU 1305 O5' DC C 7 6255 5062 5828 455 536 -380 O ATOM 1306 C5' DC C 7 -6.134 -7.102 7.895 1.00 44.60 C ANISOU 1306 C5' DC C 7 6107 5083 5754 432 645 -296 C ATOM 1307 C4' DC C 7 -5.988 -8.097 9.032 1.00 44.00 C ANISOU 1307 C4' DC C 7 5917 5070 5733 314 607 -198 C ATOM 1308 O4' DC C 7 -6.992 -7.831 10.046 1.00 41.84 O ANISOU 1308 O4' DC C 7 5501 4911 5485 164 561 -212 O ATOM 1309 C3' DC C 7 -6.154 -9.564 8.633 1.00 46.75 C ANISOU 1309 C3' DC C 7 6350 5290 6123 350 502 -164 C ATOM 1310 O3' DC C 7 -5.143 -10.350 9.246 1.00 49.82 O ANISOU 1310 O3' DC C 7 6690 5704 6537 325 536 -55 O ATOM 1311 C2' DC C 7 -7.544 -9.923 9.157 1.00 44.58 C ANISOU 1311 C2' DC C 7 6007 5039 5893 235 384 -190 C ATOM 1312 C1' DC C 7 -7.658 -9.027 10.380 1.00 41.00 C ANISOU 1312 C1' DC C 7 5376 4767 5435 100 444 -176 C ATOM 1313 N1 DC C 7 -9.064 -8.691 10.741 1.00 36.63 N ANISOU 1313 N1 DC C 7 4757 4263 4897 4 366 -239 N ATOM 1314 C2 DC C 7 -9.613 -9.185 11.929 1.00 36.19 C ANISOU 1314 C2 DC C 7 4556 4304 4889 -144 311 -185 C ATOM 1315 O2 DC C 7 -8.919 -9.896 12.665 1.00 39.05 O ANISOU 1315 O2 DC C 7 4848 4710 5281 -194 328 -86 O ATOM 1316 N3 DC C 7 -10.895 -8.867 12.241 1.00 34.16 N ANISOU 1316 N3 DC C 7 4241 4094 4646 -228 241 -242 N ATOM 1317 C4 DC C 7 -11.611 -8.096 11.420 1.00 33.96 C ANISOU 1317 C4 DC C 7 4296 4020 4589 -170 225 -348 C ATOM 1318 N4 DC C 7 -12.870 -7.810 11.768 1.00 32.76 N ANISOU 1318 N4 DC C 7 4081 3916 4451 -257 155 -401 N ATOM 1319 C5 DC C 7 -11.068 -7.585 10.204 1.00 32.10 C ANISOU 1319 C5 DC C 7 4207 3685 4304 -20 280 -405 C ATOM 1320 C6 DC C 7 -9.804 -7.905 9.908 1.00 34.36 C ANISOU 1320 C6 DC C 7 4550 3929 4578 63 350 -347 C ATOM 1321 P DT C 8 -4.787 -11.804 8.665 1.00 51.07 P ANISOU 1321 P DT C 8 6959 5719 6728 403 465 -6 P ATOM 1322 OP1 DT C 8 -3.324 -11.991 8.791 1.00 53.52 O ANISOU 1322 OP1 DT C 8 7269 6042 7023 450 563 77 O ATOM 1323 OP2 DT C 8 -5.437 -11.936 7.342 1.00 50.26 O ANISOU 1323 OP2 DT C 8 7021 5467 6611 522 391 -95 O ATOM 1324 O5' DT C 8 -5.518 -12.805 9.672 1.00 50.25 O ANISOU 1324 O5' DT C 8 6745 5654 6696 261 360 50 O ATOM 1325 C5' DT C 8 -5.117 -12.855 11.033 1.00 48.52 C ANISOU 1325 C5' DT C 8 6357 5578 6499 130 405 138 C ATOM 1326 C4' DT C 8 -6.039 -13.754 11.833 1.00 46.79 C ANISOU 1326 C4' DT C 8 6047 5384 6347 5 292 175 C ATOM 1327 O4' DT C 8 -7.286 -13.068 12.084 1.00 41.64 O ANISOU 1327 O4' DT C 8 5335 4792 5694 -72 246 102 O ATOM 1328 C3' DT C 8 -6.404 -15.077 11.152 1.00 50.44 C ANISOU 1328 C3' DT C 8 6621 5688 6857 61 171 183 C ATOM 1329 O3' DT C 8 -5.976 -16.167 11.957 1.00 55.90 O ANISOU 1329 O3' DT C 8 7235 6401 7602 -9 145 292 O ATOM 1330 C2' DT C 8 -7.934 -15.031 11.017 1.00 48.17 C ANISOU 1330 C2' DT C 8 6333 5376 6594 12 59 106 C ATOM 1331 C1' DT C 8 -8.328 -14.005 12.068 1.00 43.09 C ANISOU 1331 C1' DT C 8 5529 4909 5934 -115 111 99 C ATOM 1332 N1 DT C 8 -9.599 -13.288 11.759 1.00 38.66 N ANISOU 1332 N1 DT C 8 4979 4349 5360 -134 58 -5 N ATOM 1333 C2 DT C 8 -10.609 -13.281 12.692 1.00 37.71 C ANISOU 1333 C2 DT C 8 4727 4325 5275 -274 -2 1 C ATOM 1334 O2 DT C 8 -10.524 -13.837 13.772 1.00 38.24 O ANISOU 1334 O2 DT C 8 4667 4480 5384 -384 -14 88 O ATOM 1335 N3 DT C 8 -11.732 -12.595 12.315 1.00 35.26 N ANISOU 1335 N3 DT C 8 4438 4008 4949 -279 -47 -99 N ATOM 1336 C4 DT C 8 -11.942 -11.929 11.121 1.00 33.92 C ANISOU 1336 C4 DT C 8 4407 3746 4734 -160 -38 -202 C ATOM 1337 O4 DT C 8 -12.990 -11.340 10.874 1.00 31.66 O ANISOU 1337 O4 DT C 8 4130 3463 4438 -176 -82 -287 O ATOM 1338 C5 DT C 8 -10.843 -11.975 10.186 1.00 34.56 C ANISOU 1338 C5 DT C 8 4621 3731 4779 -15 26 -200 C ATOM 1339 C7 DT C 8 -10.955 -11.288 8.857 1.00 33.03 C ANISOU 1339 C7 DT C 8 4581 3435 4532 124 43 -303 C ATOM 1340 C6 DT C 8 -9.737 -12.644 10.546 1.00 36.01 C ANISOU 1340 C6 DT C 8 4785 3921 4978 -9 71 -103 C ATOM 1341 P DC C 9 -6.001 -17.666 11.379 1.00 59.66 P ANISOU 1341 P DC C 9 7816 6719 8135 50 37 326 P ATOM 1342 OP1 DC C 9 -4.760 -18.336 11.827 1.00 64.05 O ANISOU 1342 OP1 DC C 9 8341 7291 8704 52 92 434 O ATOM 1343 OP2 DC C 9 -6.317 -17.598 9.934 1.00 59.32 O ANISOU 1343 OP2 DC C 9 7953 6522 8064 195 -6 230 O ATOM 1344 O5' DC C 9 -7.244 -18.336 12.128 1.00 60.24 O ANISOU 1344 O5' DC C 9 7790 6819 8280 -84 -88 345 O ATOM 1345 C5' DC C 9 -7.301 -18.318 13.547 1.00 59.97 C ANISOU 1345 C5' DC C 9 7570 6943 8273 -239 -67 421 C ATOM 1346 C4' DC C 9 -8.720 -18.539 14.037 1.00 58.28 C ANISOU 1346 C4' DC C 9 7277 6757 8108 -350 -178 402 C ATOM 1347 O4' DC C 9 -9.552 -17.433 13.631 1.00 52.38 O ANISOU 1347 O4' DC C 9 6553 6030 7317 -339 -174 292 O ATOM 1348 C3' DC C 9 -9.403 -19.799 13.496 1.00 61.63 C ANISOU 1348 C3' DC C 9 7785 7032 8602 -325 -322 403 C ATOM 1349 O3' DC C 9 -9.581 -20.743 14.545 1.00 66.59 O ANISOU 1349 O3' DC C 9 8288 7714 9301 -446 -379 504 O ATOM 1350 C2' DC C 9 -10.751 -19.304 12.940 1.00 57.13 C ANISOU 1350 C2' DC C 9 7260 6419 8026 -320 -399 293 C ATOM 1351 C1' DC C 9 -10.867 -17.899 13.514 1.00 52.17 C ANISOU 1351 C1' DC C 9 6532 5949 7340 -383 -304 255 C ATOM 1352 N1 DC C 9 -11.630 -16.961 12.641 1.00 46.41 N ANISOU 1352 N1 DC C 9 5891 5177 6566 -320 -314 129 N ATOM 1353 C2 DC C 9 -12.805 -16.370 13.120 1.00 43.03 C ANISOU 1353 C2 DC C 9 5374 4833 6142 -417 -354 82 C ATOM 1354 O2 DC C 9 -13.187 -16.632 14.267 1.00 42.92 O ANISOU 1354 O2 DC C 9 5210 4930 6169 -554 -379 146 O ATOM 1355 N3 DC C 9 -13.489 -15.521 12.314 1.00 39.65 N ANISOU 1355 N3 DC C 9 5028 4364 5674 -359 -363 -33 N ATOM 1356 C4 DC C 9 -13.043 -15.264 11.083 1.00 39.32 C ANISOU 1356 C4 DC C 9 5147 4205 5588 -209 -334 -97 C ATOM 1357 N4 DC C 9 -13.753 -14.421 10.325 1.00 35.53 N ANISOU 1357 N4 DC C 9 4742 3690 5069 -155 -344 -207 N ATOM 1358 C5 DC C 9 -11.850 -15.858 10.576 1.00 42.02 C ANISOU 1358 C5 DC C 9 5581 4463 5923 -105 -293 -48 C ATOM 1359 C6 DC C 9 -11.183 -16.693 11.381 1.00 45.53 C ANISOU 1359 C6 DC C 9 5944 4947 6409 -166 -285 63 C ATOM 1360 P DC C 10 -10.249 -22.174 14.246 1.00 68.68 P ANISOU 1360 P DC C 10 8603 7840 9654 -447 -531 530 P ATOM 1361 OP1 DC C 10 -9.709 -23.133 15.235 1.00 73.93 O ANISOU 1361 OP1 DC C 10 9158 8556 10375 -532 -536 659 O ATOM 1362 OP2 DC C 10 -10.105 -22.452 12.800 1.00 70.27 O ANISOU 1362 OP2 DC C 10 9000 7858 9840 -286 -569 459 O ATOM 1363 O5' DC C 10 -11.801 -21.941 14.550 1.00 64.90 O ANISOU 1363 O5' DC C 10 8056 7397 9205 -543 -625 479 O ATOM 1364 C5' DC C 10 -12.207 -21.445 15.821 1.00 61.65 C ANISOU 1364 C5' DC C 10 7463 7165 8797 -691 -595 519 C ATOM 1365 C4' DC C 10 -13.718 -21.341 15.901 1.00 58.83 C ANISOU 1365 C4' DC C 10 7070 6812 8473 -762 -699 464 C ATOM 1366 O4' DC C 10 -14.169 -20.198 15.131 1.00 53.13 O ANISOU 1366 O4' DC C 10 6428 6075 7686 -696 -671 340 O ATOM 1367 C3' DC C 10 -14.475 -22.556 15.361 1.00 62.68 C ANISOU 1367 C3' DC C 10 7631 7143 9041 -742 -849 465 C ATOM 1368 O3' DC C 10 -15.468 -22.965 16.290 1.00 66.25 O ANISOU 1368 O3' DC C 10 7948 7668 9559 -882 -931 512 O ATOM 1369 C2' DC C 10 -15.092 -22.057 14.053 1.00 58.74 C ANISOU 1369 C2' DC C 10 7290 6519 8508 -629 -889 332 C ATOM 1370 C1' DC C 10 -15.261 -20.570 14.324 1.00 52.93 C ANISOU 1370 C1' DC C 10 6497 5919 7696 -659 -793 268 C ATOM 1371 N1 DC C 10 -15.229 -19.739 13.087 1.00 48.24 N ANISOU 1371 N1 DC C 10 6055 5239 7034 -525 -759 150 N ATOM 1372 C2 DC C 10 -16.319 -18.920 12.771 1.00 46.16 C ANISOU 1372 C2 DC C 10 5806 4987 6747 -534 -791 49 C ATOM 1373 O2 DC C 10 -17.296 -18.897 13.528 1.00 46.90 O ANISOU 1373 O2 DC C 10 5783 5161 6875 -655 -847 59 O ATOM 1374 N3 DC C 10 -16.271 -18.172 11.640 1.00 42.44 N ANISOU 1374 N3 DC C 10 5473 4438 6214 -410 -759 -56 N ATOM 1375 C4 DC C 10 -15.197 -18.224 10.849 1.00 43.26 C ANISOU 1375 C4 DC C 10 5697 4459 6280 -280 -697 -59 C ATOM 1376 N4 DC C 10 -15.194 -17.469 9.746 1.00 40.08 N ANISOU 1376 N4 DC C 10 5427 3985 5817 -159 -667 -161 N ATOM 1377 C5 DC C 10 -14.078 -19.054 11.155 1.00 46.36 C ANISOU 1377 C5 DC C 10 6078 4840 6695 -268 -665 42 C ATOM 1378 C6 DC C 10 -14.138 -19.786 12.272 1.00 48.52 C ANISOU 1378 C6 DC C 10 6216 5189 7030 -392 -697 143 C ATOM 1379 P DC C 11 -16.152 -24.412 16.151 1.00 68.94 P ANISOU 1379 P DC C 11 8309 7879 10005 -902 -1085 556 P ATOM 1380 OP1 DC C 11 -16.474 -24.890 17.514 1.00 72.76 O ANISOU 1380 OP1 DC C 11 8608 8491 10547 -1058 -1111 665 O ATOM 1381 OP2 DC C 11 -15.295 -25.232 15.266 1.00 70.85 O ANISOU 1381 OP2 DC C 11 8695 7964 10261 -777 -1100 568 O ATOM 1382 O5' DC C 11 -17.514 -24.114 15.372 1.00 67.08 O ANISOU 1382 O5' DC C 11 8151 7559 9777 -876 -1184 441 O ATOM 1383 C5' DC C 11 -18.455 -23.201 15.919 1.00 63.97 C ANISOU 1383 C5' DC C 11 7656 7289 9360 -968 -1177 399 C ATOM 1384 C4' DC C 11 -19.473 -22.787 14.874 1.00 61.79 C ANISOU 1384 C4' DC C 11 7498 6907 9071 -901 -1248 272 C ATOM 1385 O4' DC C 11 -18.856 -21.908 13.921 1.00 57.57 O ANISOU 1385 O4' DC C 11 7094 6330 8451 -772 -1162 182 O ATOM 1386 C3' DC C 11 -20.044 -23.931 14.044 1.00 65.42 C ANISOU 1386 C3' DC C 11 8071 7177 9609 -843 -1392 255 C ATOM 1387 O3' DC C 11 -21.297 -24.340 14.580 1.00 68.57 O ANISOU 1387 O3' DC C 11 8377 7596 10080 -953 -1502 273 O ATOM 1388 C2' DC C 11 -20.197 -23.340 12.628 1.00 62.00 C ANISOU 1388 C2' DC C 11 7819 6618 9119 -697 -1395 121 C ATOM 1389 C1' DC C 11 -19.632 -21.923 12.754 1.00 55.07 C ANISOU 1389 C1' DC C 11 6920 5866 8138 -681 -1248 78 C ATOM 1390 N1 DC C 11 -18.772 -21.518 11.605 1.00 50.19 N ANISOU 1390 N1 DC C 11 6466 5153 7452 -521 -1180 11 N ATOM 1391 C2 DC C 11 -19.236 -20.557 10.700 1.00 46.89 C ANISOU 1391 C2 DC C 11 6148 4696 6973 -440 -1167 -113 C ATOM 1392 O2 DC C 11 -20.355 -20.058 10.873 1.00 44.36 O ANISOU 1392 O2 DC C 11 5780 4419 6657 -505 -1212 -167 O ATOM 1393 N3 DC C 11 -18.444 -20.199 9.659 1.00 45.61 N ANISOU 1393 N3 DC C 11 6131 4450 6749 -293 -1104 -168 N ATOM 1394 C4 DC C 11 -17.244 -20.761 9.509 1.00 46.68 C ANISOU 1394 C4 DC C 11 6313 4542 6881 -226 -1056 -106 C ATOM 1395 N4 DC C 11 -16.499 -20.375 8.468 1.00 44.14 N ANISOU 1395 N4 DC C 11 6134 4140 6496 -78 -994 -161 N ATOM 1396 C5 DC C 11 -16.754 -21.743 10.420 1.00 50.38 C ANISOU 1396 C5 DC C 11 6682 5048 7412 -307 -1070 18 C ATOM 1397 C6 DC C 11 -17.544 -22.089 11.442 1.00 51.29 C ANISOU 1397 C6 DC C 11 6654 5246 7589 -453 -1132 73 C ATOM 1398 P DA C 12 -22.133 -25.524 13.886 1.00 79.88 P ANISOU 1398 P DA C 12 11451 8958 9942 -2779 455 149 P ATOM 1399 OP1 DA C 12 -22.933 -26.180 14.944 1.00 89.51 O ANISOU 1399 OP1 DA C 12 12596 10266 11149 -2918 472 227 O ATOM 1400 OP2 DA C 12 -21.201 -26.331 13.067 1.00 77.41 O ANISOU 1400 OP2 DA C 12 11186 8451 9775 -2677 398 88 O ATOM 1401 O5' DA C 12 -23.127 -24.757 12.896 1.00 79.13 O ANISOU 1401 O5' DA C 12 11214 9134 9719 -2734 463 30 O ATOM 1402 C5' DA C 12 -23.973 -23.731 13.400 1.00 78.62 C ANISOU 1402 C5' DA C 12 11028 9339 9506 -2656 499 60 C ATOM 1403 C4' DA C 12 -24.715 -23.035 12.273 1.00 75.78 C ANISOU 1403 C4' DA C 12 10532 9214 9047 -2559 494 -61 C ATOM 1404 O4' DA C 12 -23.765 -22.369 11.401 1.00 67.05 O ANISOU 1404 O4' DA C 12 9495 8014 7966 -2356 469 -114 O ATOM 1405 C3' DA C 12 -25.551 -23.955 11.384 1.00 81.41 C ANISOU 1405 C3' DA C 12 11156 10002 9774 -2729 473 -169 C ATOM 1406 O3' DA C 12 -26.816 -23.358 11.128 1.00 85.13 O ANISOU 1406 O3' DA C 12 11449 10787 10108 -2718 493 -218 O ATOM 1407 C2' DA C 12 -24.713 -24.086 10.111 1.00 74.98 C ANISOU 1407 C2' DA C 12 10416 9039 9035 -2643 432 -271 C ATOM 1408 C1' DA C 12 -23.984 -22.751 10.061 1.00 65.91 C ANISOU 1408 C1' DA C 12 9306 7898 7838 -2381 437 -244 C ATOM 1409 N9 DA C 12 -22.686 -22.828 9.396 1.00 57.41 N ANISOU 1409 N9 DA C 12 8370 6579 6866 -2275 405 -276 N ATOM 1410 C8 DA C 12 -21.688 -23.728 9.646 1.00 55.96 C ANISOU 1410 C8 DA C 12 8340 6097 6825 -2352 386 -237 C ATOM 1411 N7 DA C 12 -20.623 -23.561 8.900 1.00 50.37 N ANISOU 1411 N7 DA C 12 7733 5219 6186 -2222 359 -279 N ATOM 1412 C5 DA C 12 -20.944 -22.476 8.102 1.00 45.96 C ANISOU 1412 C5 DA C 12 7080 4862 5521 -2047 360 -348 C ATOM 1413 C6 DA C 12 -20.232 -21.799 7.094 1.00 37.76 C ANISOU 1413 C6 DA C 12 6074 3787 4485 -1853 339 -412 C ATOM 1414 N6 DA C 12 -18.998 -22.140 6.709 1.00 34.26 N ANISOU 1414 N6 DA C 12 5778 3078 4161 -1803 312 -422 N ATOM 1415 N1 DA C 12 -20.840 -20.754 6.494 1.00 35.76 N ANISOU 1415 N1 DA C 12 5695 3783 4111 -1712 347 -463 N ATOM 1416 C2 DA C 12 -22.076 -20.416 6.883 1.00 41.14 C ANISOU 1416 C2 DA C 12 6228 4728 4677 -1762 375 -451 C ATOM 1417 N3 DA C 12 -22.842 -20.975 7.818 1.00 48.39 N ANISOU 1417 N3 DA C 12 7101 5708 5578 -1940 397 -396 N ATOM 1418 C4 DA C 12 -22.212 -22.010 8.395 1.00 50.65 C ANISOU 1418 C4 DA C 12 7515 5745 5985 -2077 388 -345 C ATOM 1419 P DT C 13 -27.942 -24.153 10.302 1.00 83.96 P ANISOU 1419 P DT C 13 11172 10787 9941 -2895 478 -329 P ATOM 1420 OP1 DT C 13 -29.244 -23.873 10.947 1.00 91.65 O ANISOU 1420 OP1 DT C 13 11997 12028 10800 -2968 515 -294 O ATOM 1421 OP2 DT C 13 -27.499 -25.554 10.130 1.00 87.00 O ANISOU 1421 OP2 DT C 13 11652 10933 10470 -3076 451 -351 O ATOM 1422 O5' DT C 13 -27.922 -23.443 8.872 1.00 78.19 O ANISOU 1422 O5' DT C 13 10383 10169 9157 -2732 452 -453 O ATOM 1423 C5' DT C 13 -28.006 -22.027 8.791 1.00 72.24 C ANISOU 1423 C5' DT C 13 9566 9587 8293 -2512 470 -440 C ATOM 1424 C4' DT C 13 -27.625 -21.540 7.406 1.00 65.88 C ANISOU 1424 C4' DT C 13 8750 8804 7478 -2358 438 -547 C ATOM 1425 O4' DT C 13 -26.221 -21.781 7.175 1.00 58.94 O ANISOU 1425 O4' DT C 13 8043 7633 6717 -2287 412 -542 O ATOM 1426 C3' DT C 13 -28.372 -22.221 6.255 1.00 70.84 C ANISOU 1426 C3' DT C 13 9279 9544 8093 -2480 409 -678 C ATOM 1427 O3' DT C 13 -29.168 -21.265 5.569 1.00 71.73 O ANISOU 1427 O3' DT C 13 9237 9940 8077 -2362 415 -733 O ATOM 1428 C2' DT C 13 -27.262 -22.793 5.356 1.00 65.65 C ANISOU 1428 C2' DT C 13 8752 8641 7552 -2459 367 -749 C ATOM 1429 C1' DT C 13 -26.029 -22.026 5.809 1.00 57.18 C ANISOU 1429 C1' DT C 13 7814 7394 6519 -2263 375 -665 C ATOM 1430 N1 DT C 13 -24.757 -22.787 5.642 1.00 53.19 N ANISOU 1430 N1 DT C 13 7486 6562 6162 -2285 347 -668 N ATOM 1431 C2 DT C 13 -23.828 -22.352 4.726 1.00 46.57 C ANISOU 1431 C2 DT C 13 6716 5623 5354 -2117 322 -721 C ATOM 1432 O2 DT C 13 -23.986 -21.365 4.030 1.00 45.03 O ANISOU 1432 O2 DT C 13 6444 5594 5071 -1948 320 -763 O ATOM 1433 N3 DT C 13 -22.695 -23.119 4.653 1.00 43.14 N ANISOU 1433 N3 DT C 13 6444 4886 5062 -2152 299 -719 N ATOM 1434 C4 DT C 13 -22.405 -24.254 5.388 1.00 46.10 C ANISOU 1434 C4 DT C 13 6914 5051 5552 -2335 299 -668 C ATOM 1435 O4 DT C 13 -21.356 -24.876 5.249 1.00 43.19 O ANISOU 1435 O4 DT C 13 6687 4410 5312 -2351 279 -669 O ATOM 1436 C5 DT C 13 -23.422 -24.656 6.330 1.00 53.25 C ANISOU 1436 C5 DT C 13 7738 6078 6418 -2506 326 -610 C ATOM 1437 C7 DT C 13 -23.221 -25.872 7.184 1.00 58.02 C ANISOU 1437 C7 DT C 13 8428 6476 7140 -2711 330 -544 C ATOM 1438 C6 DT C 13 -24.536 -23.911 6.411 1.00 56.67 C ANISOU 1438 C6 DT C 13 8015 6809 6708 -2473 348 -614 C ATOM 1439 P DT C 14 -30.082 -21.709 4.325 1.00 75.38 P ANISOU 1439 P DT C 14 9565 10586 8492 -2457 386 -871 P ATOM 1440 OP1 DT C 14 -31.255 -20.808 4.301 1.00 80.02 O ANISOU 1440 OP1 DT C 14 9971 11501 8934 -2397 412 -871 O ATOM 1441 OP2 DT C 14 -30.282 -23.173 4.392 1.00 81.52 O ANISOU 1441 OP2 DT C 14 10375 11240 9359 -2709 370 -909 O ATOM 1442 O5' DT C 14 -29.169 -21.387 3.055 1.00 68.47 O ANISOU 1442 O5' DT C 14 8749 9621 7645 -2296 349 -956 O ATOM 1443 C5' DT C 14 -28.585 -20.100 2.917 1.00 62.67 C ANISOU 1443 C5' DT C 14 8030 8914 6866 -2043 359 -919 C ATOM 1444 C4' DT C 14 -27.610 -20.072 1.757 1.00 59.03 C ANISOU 1444 C4' DT C 14 7650 8320 6459 -1927 321 -997 C ATOM 1445 O4' DT C 14 -26.463 -20.899 2.066 1.00 55.54 O ANISOU 1445 O4' DT C 14 7393 7548 6161 -1987 305 -974 O ATOM 1446 C3' DT C 14 -28.173 -20.589 0.429 1.00 63.62 C ANISOU 1446 C3' DT C 14 8137 9026 7010 -2007 285 -1138 C ATOM 1447 O3' DT C 14 -28.037 -19.590 -0.573 1.00 61.97 O ANISOU 1447 O3' DT C 14 7868 8950 6729 -1803 273 -1184 O ATOM 1448 C2' DT C 14 -27.329 -21.832 0.116 1.00 62.14 C ANISOU 1448 C2' DT C 14 8092 8553 6963 -2136 254 -1194 C ATOM 1449 C1' DT C 14 -26.056 -21.571 0.904 1.00 54.19 C ANISOU 1449 C1' DT C 14 7260 7282 6049 -2026 265 -1089 C ATOM 1450 N1 DT C 14 -25.339 -22.815 1.308 1.00 53.66 N ANISOU 1450 N1 DT C 14 7341 6916 6130 -2185 253 -1079 N ATOM 1451 C2 DT C 14 -24.083 -23.061 0.806 1.00 48.41 C ANISOU 1451 C2 DT C 14 6822 5999 5571 -2115 228 -1106 C ATOM 1452 O2 DT C 14 -23.512 -22.309 0.036 1.00 44.05 O ANISOU 1452 O2 DT C 14 6286 5456 4996 -1927 215 -1139 O ATOM 1453 N3 DT C 14 -23.512 -24.229 1.239 1.00 49.46 N ANISOU 1453 N3 DT C 14 7082 5868 5844 -2274 221 -1090 N ATOM 1454 C4 DT C 14 -24.061 -25.155 2.107 1.00 56.59 C ANISOU 1454 C4 DT C 14 7978 6733 6790 -2491 236 -1047 C ATOM 1455 O4 DT C 14 -23.468 -26.177 2.438 1.00 58.49 O ANISOU 1455 O4 DT C 14 8335 6724 7166 -2620 229 -1030 O ATOM 1456 C5 DT C 14 -25.381 -24.836 2.597 1.00 61.91 C ANISOU 1456 C5 DT C 14 8496 7683 7345 -2554 261 -1020 C ATOM 1457 C7 DT C 14 -26.079 -25.766 3.544 1.00 69.65 C ANISOU 1457 C7 DT C 14 9453 8654 8359 -2785 280 -970 C ATOM 1458 C6 DT C 14 -25.949 -23.694 2.178 1.00 59.89 C ANISOU 1458 C6 DT C 14 8117 7687 6951 -2400 269 -1039 C ATOM 1459 P DT C 15 -28.702 -19.794 -2.021 1.00 74.03 P ANISOU 1459 P DT C 15 9266 10672 8188 -1837 239 -1325 P ATOM 1460 OP1 DT C 15 -29.234 -18.483 -2.454 1.00 74.95 O ANISOU 1460 OP1 DT C 15 9243 11059 8176 -1649 252 -1314 O ATOM 1461 OP2 DT C 15 -29.601 -20.968 -1.960 1.00 81.32 O ANISOU 1461 OP2 DT C 15 10129 11648 9122 -2097 231 -1385 O ATOM 1462 O5' DT C 15 -27.459 -20.169 -2.951 1.00 68.63 O ANISOU 1462 O5' DT C 15 8719 9758 7599 -1776 202 -1397 O ATOM 1463 C5' DT C 15 -26.308 -19.339 -2.950 1.00 59.86 C ANISOU 1463 C5' DT C 15 7716 8503 6524 -1556 205 -1340 C ATOM 1464 C4' DT C 15 -25.130 -20.048 -3.587 1.00 55.52 C ANISOU 1464 C4' DT C 15 7319 7682 6094 -1563 172 -1402 C ATOM 1465 O4' DT C 15 -24.742 -21.177 -2.772 1.00 55.96 O ANISOU 1465 O4' DT C 15 7500 7490 6273 -1744 174 -1372 O ATOM 1466 C3' DT C 15 -25.390 -20.601 -4.993 1.00 58.62 C ANISOU 1466 C3' DT C 15 7649 8160 6465 -1628 134 -1552 C ATOM 1467 O3' DT C 15 -24.510 -19.979 -5.922 1.00 55.10 O ANISOU 1467 O3' DT C 15 7249 7666 6021 -1431 115 -1585 O ATOM 1468 C2' DT C 15 -25.124 -22.110 -4.867 1.00 60.96 C ANISOU 1468 C2' DT C 15 8045 8230 6887 -1858 117 -1607 C ATOM 1469 C1' DT C 15 -24.273 -22.196 -3.611 1.00 56.44 C ANISOU 1469 C1' DT C 15 7628 7396 6420 -1847 140 -1480 C ATOM 1470 N1 DT C 15 -24.399 -23.498 -2.891 1.00 59.30 N ANISOU 1470 N1 DT C 15 8051 7594 6884 -2090 143 -1473 N ATOM 1471 C2 DT C 15 -23.303 -24.324 -2.798 1.00 56.47 C ANISOU 1471 C2 DT C 15 7862 6918 6677 -2144 131 -1474 C ATOM 1472 O2 DT C 15 -22.218 -24.050 -3.277 1.00 50.66 O ANISOU 1472 O2 DT C 15 7231 6023 5994 -2003 117 -1484 O ATOM 1473 N3 DT C 15 -23.524 -25.493 -2.118 1.00 60.36 N ANISOU 1473 N3 DT C 15 8393 7280 7260 -2370 137 -1460 N ATOM 1474 C4 DT C 15 -24.705 -25.910 -1.535 1.00 67.08 C ANISOU 1474 C4 DT C 15 9135 8288 8066 -2545 154 -1446 C ATOM 1475 O4 DT C 15 -24.803 -26.981 -0.944 1.00 71.92 O ANISOU 1475 O4 DT C 15 9792 8761 8772 -2743 159 -1429 O ATOM 1476 C5 DT C 15 -25.816 -24.997 -1.669 1.00 69.56 C ANISOU 1476 C5 DT C 15 9276 8937 8217 -2477 166 -1448 C ATOM 1477 C7 DT C 15 -27.151 -25.341 -1.077 1.00 78.12 C ANISOU 1477 C7 DT C 15 10228 10215 9238 -2652 185 -1432 C ATOM 1478 C6 DT C 15 -25.612 -23.849 -2.334 1.00 64.59 C ANISOU 1478 C6 DT C 15 8605 8435 7499 -2256 160 -1461 C ATOM 1479 P DC C 16 -24.523 -20.392 -7.475 1.00 63.26 P ANISOU 1479 P DC C 16 8236 8769 7032 -1451 74 -1739 P ATOM 1480 OP1 DC C 16 -24.229 -19.168 -8.251 1.00 61.53 O ANISOU 1480 OP1 DC C 16 7967 8678 6734 -1203 70 -1733 O ATOM 1481 OP2 DC C 16 -25.760 -21.155 -7.760 1.00 71.76 O ANISOU 1481 OP2 DC C 16 9178 10035 8052 -1660 64 -1828 O ATOM 1482 O5' DC C 16 -23.276 -21.382 -7.605 1.00 59.13 O ANISOU 1482 O5' DC C 16 7904 7894 6669 -1515 55 -1778 O ATOM 1483 C5' DC C 16 -22.019 -20.999 -7.059 1.00 52.00 C ANISOU 1483 C5' DC C 16 7161 6738 5857 -1375 65 -1685 C ATOM 1484 C4' DC C 16 -21.022 -22.140 -7.129 1.00 50.71 C ANISOU 1484 C4' DC C 16 7165 6252 5850 -1483 48 -1728 C ATOM 1485 O4' DC C 16 -21.425 -23.199 -6.222 1.00 53.44 O ANISOU 1485 O4' DC C 16 7538 6499 6267 -1714 58 -1706 O ATOM 1486 C3' DC C 16 -20.876 -22.786 -8.507 1.00 53.22 C ANISOU 1486 C3' DC C 16 7471 6567 6181 -1535 12 -1885 C ATOM 1487 O3' DC C 16 -19.502 -22.979 -8.801 1.00 49.70 O ANISOU 1487 O3' DC C 16 7190 5841 5852 -1452 0 -1892 O ATOM 1488 C2' DC C 16 -21.614 -24.116 -8.359 1.00 58.47 C ANISOU 1488 C2' DC C 16 8104 7221 6891 -1813 7 -1958 C ATOM 1489 C1' DC C 16 -21.379 -24.436 -6.892 1.00 56.72 C ANISOU 1489 C1' DC C 16 7982 6810 6760 -1891 34 -1829 C ATOM 1490 N1 DC C 16 -22.418 -25.325 -6.300 1.00 62.81 N ANISOU 1490 N1 DC C 16 8680 7648 7535 -2133 44 -1839 N ATOM 1491 C2 DC C 16 -22.047 -26.560 -5.758 1.00 64.23 C ANISOU 1491 C2 DC C 16 8971 7572 7863 -2321 45 -1836 C ATOM 1492 O2 DC C 16 -20.857 -26.897 -5.782 1.00 61.79 O ANISOU 1492 O2 DC C 16 8817 6983 7678 -2284 38 -1827 O ATOM 1493 N3 DC C 16 -23.006 -27.355 -5.220 1.00 68.76 N ANISOU 1493 N3 DC C 16 9474 8209 8442 -2539 55 -1841 N ATOM 1494 C4 DC C 16 -24.278 -26.954 -5.214 1.00 73.72 C ANISOU 1494 C4 DC C 16 9933 9143 8935 -2572 63 -1851 C ATOM 1495 N4 DC C 16 -25.188 -27.770 -4.673 1.00 81.86 N ANISOU 1495 N4 DC C 16 10900 10226 9979 -2790 74 -1854 N ATOM 1496 C5 DC C 16 -24.674 -25.699 -5.761 1.00 71.74 C ANISOU 1496 C5 DC C 16 9568 9157 8533 -2382 62 -1854 C ATOM 1497 C6 DC C 16 -23.721 -24.926 -6.289 1.00 65.96 C ANISOU 1497 C6 DC C 16 8906 8358 7799 -2167 52 -1847 C ATOM 1498 P DG C 17 -19.008 -23.089 -10.325 1.00 84.48 P ANISOU 1498 P DG C 17 12519 9227 10353 -1677 3602 -1734 P ATOM 1499 OP1 DG C 17 -17.842 -22.192 -10.485 1.00 88.48 O ANISOU 1499 OP1 DG C 17 13016 9546 11056 -1589 3748 -1640 O ATOM 1500 OP2 DG C 17 -20.191 -22.922 -11.197 1.00 85.70 O ANISOU 1500 OP2 DG C 17 12823 9407 10333 -1379 3518 -1708 O ATOM 1501 O5' DG C 17 -18.516 -24.603 -10.450 1.00 77.21 O ANISOU 1501 O5' DG C 17 11712 8263 9363 -1787 3511 -1786 O ATOM 1502 C5' DG C 17 -17.607 -25.133 -9.494 1.00 72.59 C ANISOU 1502 C5' DG C 17 10971 7721 8890 -2155 3544 -1852 C ATOM 1503 C4' DG C 17 -17.513 -26.640 -9.622 1.00 67.14 C ANISOU 1503 C4' DG C 17 10369 7010 8131 -2256 3255 -1881 C ATOM 1504 O4' DG C 17 -18.575 -27.264 -8.855 1.00 62.13 O ANISOU 1504 O4' DG C 17 9498 6666 7441 -2543 2845 -1817 O ATOM 1505 C3' DG C 17 -17.645 -27.169 -11.049 1.00 67.59 C ANISOU 1505 C3' DG C 17 10765 6820 8095 -1818 3111 -1859 C ATOM 1506 O3' DG C 17 -16.658 -28.156 -11.292 1.00 66.70 O ANISOU 1506 O3' DG C 17 10706 6549 8086 -1813 2929 -1822 O ATOM 1507 C2' DG C 17 -19.057 -27.757 -11.088 1.00 63.79 C ANISOU 1507 C2' DG C 17 10252 6501 7484 -1830 2687 -1804 C ATOM 1508 C1' DG C 17 -19.245 -28.214 -9.651 1.00 59.62 C ANISOU 1508 C1' DG C 17 9345 6274 7034 -2345 2440 -1747 C ATOM 1509 N9 DG C 17 -20.643 -28.255 -9.233 1.00 57.57 N ANISOU 1509 N9 DG C 17 8937 6288 6648 -2475 2190 -1709 N ATOM 1510 C8 DG C 17 -21.618 -27.330 -9.515 1.00 59.68 C ANISOU 1510 C8 DG C 17 9273 6634 6769 -2292 2374 -1772 C ATOM 1511 N7 DG C 17 -22.779 -27.626 -9.001 1.00 58.20 N ANISOU 1511 N7 DG C 17 8904 6726 6483 -2474 2070 -1717 N ATOM 1512 C5 DG C 17 -22.559 -28.822 -8.330 1.00 54.64 C ANISOU 1512 C5 DG C 17 8247 6387 6125 -2809 1652 -1597 C ATOM 1513 C6 DG C 17 -23.453 -29.626 -7.584 1.00 52.46 C ANISOU 1513 C6 DG C 17 7710 6414 5807 -3129 1192 -1474 C ATOM 1514 O6 DG C 17 -24.655 -29.431 -7.357 1.00 54.82 O ANISOU 1514 O6 DG C 17 7902 6963 5963 -3177 1066 -1453 O ATOM 1515 N1 DG C 17 -22.823 -30.759 -7.073 1.00 48.79 N ANISOU 1515 N1 DG C 17 7095 5955 5488 -3418 851 -1360 N ATOM 1516 C2 DG C 17 -21.498 -31.074 -7.262 1.00 49.65 C ANISOU 1516 C2 DG C 17 7298 5808 5758 -3388 947 -1379 C ATOM 1517 N2 DG C 17 -21.070 -32.208 -6.689 1.00 48.23 N ANISOU 1517 N2 DG C 17 6907 5714 5706 -3473 543 -1185 N ATOM 1518 N3 DG C 17 -20.651 -30.329 -7.959 1.00 52.52 N ANISOU 1518 N3 DG C 17 7903 5903 6150 -3085 1386 -1500 N ATOM 1519 C4 DG C 17 -21.249 -29.223 -8.464 1.00 54.49 C ANISOU 1519 C4 DG C 17 8298 6142 6263 -2811 1718 -1596 C ATOM 1520 P DC C 18 -16.463 -28.747 -12.771 1.00 69.99 P ANISOU 1520 P DC C 18 11460 6703 8431 -1345 2802 -1817 P ATOM 1521 OP1 DC C 18 -15.023 -29.032 -12.961 1.00 72.21 O ANISOU 1521 OP1 DC C 18 11720 6878 8840 -1289 2875 -1763 O ATOM 1522 OP2 DC C 18 -17.167 -27.843 -13.708 1.00 73.73 O ANISOU 1522 OP2 DC C 18 12036 7205 8775 -958 2937 -1734 O ATOM 1523 O5' DC C 18 -17.265 -30.128 -12.735 1.00 63.28 O ANISOU 1523 O5' DC C 18 10565 5920 7559 -1436 2175 -1748 O ATOM 1524 C5' DC C 18 -16.961 -31.093 -11.740 1.00 57.53 C ANISOU 1524 C5' DC C 18 9578 5307 6975 -1845 1823 -1679 C ATOM 1525 C4' DC C 18 -18.000 -32.197 -11.729 1.00 54.92 C ANISOU 1525 C4' DC C 18 9196 5065 6605 -1920 1236 -1590 C ATOM 1526 O4' DC C 18 -19.207 -31.723 -11.097 1.00 49.75 O ANISOU 1526 O4' DC C 18 8371 4681 5850 -2112 1205 -1552 O ATOM 1527 C3' DC C 18 -18.418 -32.703 -13.115 1.00 51.41 C ANISOU 1527 C3' DC C 18 9070 4413 6052 -1459 1024 -1612 C ATOM 1528 O3' DC C 18 -18.005 -34.052 -13.284 1.00 50.07 O ANISOU 1528 O3' DC C 18 8911 4121 5992 -1478 557 -1574 O ATOM 1529 C2' DC C 18 -19.951 -32.573 -13.129 1.00 52.40 C ANISOU 1529 C2' DC C 18 9174 4708 6028 -1450 833 -1566 C ATOM 1530 C1' DC C 18 -20.291 -32.411 -11.654 1.00 49.92 C ANISOU 1530 C1' DC C 18 8489 4709 5769 -1966 788 -1496 C ATOM 1531 N1 DC C 18 -21.532 -31.621 -11.412 1.00 51.71 N ANISOU 1531 N1 DC C 18 8646 5161 5842 -1993 890 -1496 N ATOM 1532 C2 DC C 18 -22.499 -32.103 -10.522 1.00 50.65 C ANISOU 1532 C2 DC C 18 8238 5323 5684 -2345 518 -1387 C ATOM 1533 O2 DC C 18 -22.304 -33.180 -9.944 1.00 48.71 O ANISOU 1533 O2 DC C 18 7813 5138 5556 -2639 105 -1279 O ATOM 1534 N3 DC C 18 -23.623 -31.374 -10.316 1.00 52.10 N ANISOU 1534 N3 DC C 18 8352 5728 5717 -2354 615 -1399 N ATOM 1535 C4 DC C 18 -23.797 -30.218 -10.959 1.00 55.35 C ANISOU 1535 C4 DC C 18 8961 6049 6018 -2032 1049 -1515 C ATOM 1536 N4 DC C 18 -24.920 -29.533 -10.723 1.00 56.68 N ANISOU 1536 N4 DC C 18 9051 6441 6045 -2047 1117 -1535 N ATOM 1537 C5 DC C 18 -22.823 -29.711 -11.870 1.00 57.31 C ANISOU 1537 C5 DC C 18 9490 5986 6299 -1682 1424 -1611 C ATOM 1538 C6 DC C 18 -21.719 -30.438 -12.065 1.00 55.51 C ANISOU 1538 C6 DC C 18 9320 5565 6205 -1675 1334 -1596 C TER 1539 DC C 18 HETATM 1540 ZN ZN A 501 -28.063 -5.466 3.956 1.00 34.41 ZN ANISOU 1540 ZN ZN A 501 3486 5578 4010 -347 217 359 ZN HETATM 1541 ZN ZN A 502 -7.767 -18.675 -6.843 1.00 35.11 ZN ANISOU 1541 ZN ZN A 502 4295 4144 4900 580 -99 -941 ZN HETATM 1542 ZN ZN A 503 -20.633 -9.400 29.847 1.00 44.87 ZN ANISOU 1542 ZN ZN A 503 4030 9262 3758 -864 596 -527 ZN HETATM 1543 ZN ZN A 504 -11.344 -20.911 -17.618 1.00 78.44 ZN ANISOU 1543 ZN ZN A 504 10109 12205 7490 1824 2371 -1867 ZN HETATM 1544 C1 EDO A 505 -16.855 -12.997 -0.844 1.00 68.78 C HETATM 1545 O1 EDO A 505 -16.278 -12.375 0.310 1.00 68.60 O HETATM 1546 C2 EDO A 505 -17.457 -11.929 -1.747 1.00 69.29 C HETATM 1547 O2 EDO A 505 -18.456 -11.200 -1.024 1.00 70.11 O HETATM 1548 C1 EDO A 506 -19.386 -10.990 2.873 1.00 41.12 C HETATM 1549 O1 EDO A 506 -19.751 -12.371 2.761 1.00 41.62 O HETATM 1550 C2 EDO A 506 -20.136 -10.355 4.039 1.00 40.56 C HETATM 1551 O2 EDO A 506 -19.740 -10.982 5.264 1.00 39.05 O HETATM 1552 C1 EDO A 507 -16.301 -6.688 10.906 1.00 58.42 C HETATM 1553 O1 EDO A 507 -14.989 -6.808 10.344 1.00 58.68 O HETATM 1554 C2 EDO A 507 -16.328 -7.343 12.281 1.00 58.49 C HETATM 1555 O2 EDO A 507 -16.016 -8.735 12.155 1.00 59.34 O HETATM 1556 C1 EDO A 508 -12.859 4.043 6.084 1.00 69.06 C HETATM 1557 O1 EDO A 508 -13.932 4.991 6.109 1.00 68.28 O HETATM 1558 C2 EDO A 508 -13.290 2.812 5.296 1.00 69.38 C HETATM 1559 O2 EDO A 508 -14.497 2.286 5.859 1.00 68.90 O HETATM 1560 C1 GOL A 509 0.305 -13.047 -21.570 0.50 64.16 C HETATM 1561 O1 GOL A 509 1.326 -12.938 -20.636 0.50 64.22 O HETATM 1562 C2 GOL A 509 -1.011 -13.210 -20.777 0.50 64.27 C HETATM 1563 O2 GOL A 509 -1.357 -12.050 -20.097 0.50 63.90 O HETATM 1564 C3 GOL A 509 -2.064 -13.609 -21.835 0.50 64.11 C HETATM 1565 O3 GOL A 509 -1.699 -14.873 -22.290 0.50 63.91 O HETATM 1566 O HOH A 601 -29.149 -8.186 12.316 1.00 55.78 O HETATM 1567 O HOH A 602 -11.812 -9.119 37.426 1.00 61.65 O HETATM 1568 O HOH A 603 -19.370 -10.546 23.563 1.00 45.94 O HETATM 1569 O HOH A 604 -15.737 -14.529 -4.947 1.00 55.94 O HETATM 1570 O HOH A 605 -13.764 -14.975 33.958 1.00 50.02 O HETATM 1571 O HOH A 606 -17.278 -7.874 3.387 1.00 37.49 O HETATM 1572 O HOH A 607 -13.819 -18.100 0.022 1.00 40.02 O HETATM 1573 O HOH A 608 -20.964 -8.388 9.469 1.00 44.18 O HETATM 1574 O HOH A 609 -19.098 -1.347 0.386 1.00 35.11 O HETATM 1575 O HOH A 610 -19.298 -1.447 3.070 1.00 31.96 O HETATM 1576 O HOH A 611 -14.794 -7.281 22.061 1.00 40.23 O HETATM 1577 O HOH A 612 -10.937 -8.823 5.735 1.00 41.61 O HETATM 1578 O HOH A 613 -27.603 -7.446 -2.508 1.00 47.83 O HETATM 1579 O HOH A 614 -27.535 1.400 5.939 1.00 50.02 O HETATM 1580 O HOH A 615 -14.010 -12.765 -9.094 1.00 60.41 O HETATM 1581 O HOH A 616 -10.603 -3.385 2.091 1.00 55.10 O HETATM 1582 O HOH A 617 -16.098 -10.936 34.205 1.00 57.95 O HETATM 1583 O HOH A 618 -8.434 -0.135 24.997 1.00 49.47 O HETATM 1584 O HOH A 619 -14.518 -0.352 21.387 1.00 54.17 O HETATM 1585 O HOH A 620 -16.138 -1.216 1.022 1.00 49.66 O HETATM 1586 O HOH A 621 -16.320 -1.671 3.755 1.00 51.70 O HETATM 1587 O HOH A 622 -31.721 -2.238 22.901 1.00 63.05 O HETATM 1588 O HOH A 623 -6.814 -1.039 27.367 1.00 54.27 O HETATM 1589 O HOH A 624 -5.542 -8.648 -2.925 1.00 58.77 O HETATM 1590 O HOH A 625 -27.008 2.822 10.166 1.00 61.80 O HETATM 1591 O HOH A 626 -15.107 -6.723 4.909 1.00 48.36 O HETATM 1592 O HOH A 627 -12.919 0.346 2.152 1.00 58.30 O HETATM 1593 O HOH A 628 -15.485 -3.881 5.475 1.00 45.38 O HETATM 1594 O HOH A 629 -14.281 -0.063 0.171 0.50 52.54 O HETATM 1595 O HOH A 630 -13.398 -8.278 6.904 1.00 38.26 O HETATM 1596 O HOH A 631 -26.794 5.589 14.067 1.00 68.55 O HETATM 1597 O HOH B 101 -9.561 -8.907 24.619 1.00 47.06 O HETATM 1598 O HOH B 102 1.617 -4.624 20.053 1.00 58.64 O HETATM 1599 O HOH B 103 -21.539 -10.162 7.160 1.00 47.60 O HETATM 1600 O HOH B 104 -15.159 -17.192 6.320 1.00 47.46 O HETATM 1601 O HOH B 105 -21.161 -9.204 11.975 1.00 52.45 O HETATM 1602 O HOH B 106 -16.060 -16.182 -0.213 1.00 38.93 O HETATM 1603 O HOH B 107 -20.251 -10.090 18.419 1.00 50.47 O HETATM 1604 O HOH B 108 -18.266 -9.565 13.806 1.00 40.22 O HETATM 1605 O HOH B 109 -24.067 -18.897 3.026 1.00 48.37 O HETATM 1606 O HOH B 110 -16.766 -24.894 4.638 1.00 31.83 O HETATM 1607 O HOH B 111 -11.329 -2.676 19.743 1.00 43.71 O HETATM 1608 O HOH B 112 -16.527 -8.704 21.291 1.00 60.90 O HETATM 1609 O HOH B 113 -18.169 -26.298 -4.972 1.00 55.22 O HETATM 1610 O HOH B 114 -18.752 -16.848 16.885 1.00 56.84 O HETATM 1611 O HOH B 115 -8.419 -2.104 21.037 1.00 56.91 O HETATM 1612 O HOH B 116 -16.637 -17.621 17.661 1.00 68.52 O HETATM 1613 O HOH B 117 -18.474 -28.022 3.567 1.00 31.96 O HETATM 1614 O HOH B 118 -22.432 -30.502 2.187 1.00 60.89 O HETATM 1615 O HOH B 119 -20.848 -20.414 -3.631 1.00 50.55 O HETATM 1616 O HOH B 120 -6.225 6.335 18.103 1.00 73.16 O HETATM 1617 O HOH B 121 -17.591 -23.791 -5.230 1.00 66.46 O HETATM 1618 O HOH B 122 -24.176 -18.525 0.236 1.00 55.34 O HETATM 1619 O HOH C 101 -7.713 -12.679 7.303 1.00 37.82 O HETATM 1620 O HOH C 102 -16.666 1.432 11.029 1.00 49.13 O HETATM 1621 O HOH C 103 -14.311 -10.578 8.791 1.00 38.74 O HETATM 1622 O HOH C 104 -14.863 -2.854 16.364 1.00 38.94 O HETATM 1623 O HOH C 105 -18.793 -19.142 15.756 1.00 57.30 O HETATM 1624 O HOH C 106 -5.801 -4.947 11.143 1.00 58.47 O HETATM 1625 O HOH C 107 -19.839 -22.735 -3.708 1.00 41.46 O HETATM 1626 O HOH C 108 -14.339 -0.238 4.635 1.00 57.29 O HETATM 1627 O HOH C 109 -22.311 -20.036 -1.025 1.00 43.37 O HETATM 1628 O HOH C 110 -12.790 -3.485 6.169 1.00 52.30 O HETATM 1629 O HOH C 111 -12.977 -17.621 7.973 1.00 44.77 O HETATM 1630 O HOH C 112 -19.521 0.889 16.357 1.00 57.07 O HETATM 1631 O HOH C 113 -11.344 -4.981 4.440 1.00 43.27 O HETATM 1632 O HOH C 114 -12.984 -0.627 19.092 1.00 50.21 O HETATM 1633 O HOH C 115 -6.455 -10.622 14.311 1.00 66.64 O HETATM 1634 O HOH C 116 -7.362 -0.613 22.506 1.00 61.08 O HETATM 1635 O HOH C 117 -7.717 -15.510 7.263 1.00 51.37 O HETATM 1636 O HOH C 118 -9.832 -18.220 8.567 1.00 61.94 O CONECT 64 1542 CONECT 98 1542 CONECT 217 1542 CONECT 253 1542 CONECT 312 1540 CONECT 345 1540 CONECT 461 1540 CONECT 502 1540 CONECT 562 1541 CONECT 580 1541 CONECT 691 1541 CONECT 726 1541 CONECT 754 828 1543 CONECT 798 1543 CONECT 828 754 1543 CONECT 858 1543 CONECT 1540 312 345 461 502 CONECT 1541 562 580 691 726 CONECT 1542 64 98 217 253 CONECT 1543 754 798 828 858 CONECT 1544 1545 1546 CONECT 1545 1544 CONECT 1546 1544 1547 CONECT 1547 1546 CONECT 1548 1549 1550 CONECT 1549 1548 CONECT 1550 1548 1551 CONECT 1551 1550 CONECT 1552 1553 1554 CONECT 1553 1552 CONECT 1554 1552 1555 CONECT 1555 1554 CONECT 1556 1557 1558 CONECT 1557 1556 CONECT 1558 1556 1559 CONECT 1559 1558 CONECT 1560 1561 1562 CONECT 1561 1560 CONECT 1562 1560 1563 1564 CONECT 1563 1562 CONECT 1564 1562 1565 CONECT 1565 1564 MASTER 592 0 9 5 6 0 13 6 1633 3 42 14 END
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Related entries of code: 6blw
Entries with 90% protein sequence similarity cutoff in PDBbind
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Protein Sequence Similarity
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Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
2kx5
RCSB PDB
PDBbind
18-mer
3g6p
RCSB PDB
PDBbind
18-mer
6a2i
RCSB PDB
PDBbind
18-mer
Entry Information
PDB ID
6blw
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Zinc finger Domain of WT1(+KTS form)
Ligand Name
18-mer
EC.Number
E.C.-.-.-.-
Resolution
1.84(Å)
Affinity (Kd/Ki/IC50)
Kd=10nM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) Nucleic Acids Res. Vol. 46: pp. 3864-3877
Links to External Databases
RCSB PDB
The mother database
PDBsum
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Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P19544
Entrez Gene ID
NCBI Entrez Gene ID:
7490
ASD
Information of known allosteric effects of PDB entries
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