Browse entries in the PDBbind-CN Database
HEADER RNA BINDING PROTEIN 24-JUL-10 3O3I TITLE CRYSTAL STRUCTURE OF HUMAN HIWI1 PAZ DOMAIN (RESIDUES 277-399) IN TITLE 2 COMPLEX WITH 14-MER RNA (12-BP + 2-NT OVERHANG) CONTAINING 2'-OH AT TITLE 3 ITS 3'-END COMPND MOL_ID: 1; COMPND 2 MOLECULE: PIWI-LIKE PROTEIN 1; COMPND 3 CHAIN: X; COMPND 4 FRAGMENT: PAZ DOMAIN (UNP RESIDUES 277-399); COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*U)-3'); COMPND 8 CHAIN: A; COMPND 9 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: HIWI, PIWI-LIKE PROTEIN 1, PIWIL1; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3); SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PET-28B; SOURCE 11 MOL_ID: 2; SOURCE 12 SYNTHETIC: YES; SOURCE 13 OTHER_DETAILS: CHEMICALLY SYNTHESIZED KEYWDS PIWI, PAZ, RNA SILENCING, PI-RNA, HIWI1, HILI, PAZ DOMAIN, RNA KEYWDS 2 BINDING PROTEIN EXPDTA X-RAY DIFFRACTION AUTHOR Y.TIAN,D.K.SIMANSHU,J.-B.MA,D.J.PATEL REVDAT 3 08-NOV-17 3O3I 1 REMARK REVDAT 2 02-FEB-11 3O3I 1 JRNL REVDAT 1 12-JAN-11 3O3I 0 JRNL AUTH Y.TIAN,D.K.SIMANSHU,J.B.MA,D.J.PATEL JRNL TITL INAUGURAL ARTICLE: STRUCTURAL BASIS FOR PIRNA JRNL TITL 2 2'-O-METHYLATED 3'-END RECOGNITION BY PIWI PAZ JRNL TITL 3 (PIWI/ARGONAUTE/ZWILLE) DOMAINS. JRNL REF PROC.NATL.ACAD.SCI.USA V. 108 903 2011 JRNL REFN ISSN 0027-8424 JRNL PMID 21193640 JRNL DOI 10.1073/PNAS.1017762108 REMARK 2 REMARK 2 RESOLUTION. 2.80 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.80 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 15.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 COMPLETENESS FOR RANGE (%) : 96.9 REMARK 3 NUMBER OF REFLECTIONS : 3713 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.245 REMARK 3 R VALUE (WORKING SET) : 0.243 REMARK 3 FREE R VALUE : 0.297 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.600 REMARK 3 FREE R VALUE TEST SET COUNT : 177 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.80 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.87 REMARK 3 REFLECTION IN BIN (WORKING SET) : 213 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 78.99 REMARK 3 BIN R VALUE (WORKING SET) : 0.3750 REMARK 3 BIN FREE R VALUE SET COUNT : 5 REMARK 3 BIN FREE R VALUE : 0.3380 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 871 REMARK 3 NUCLEIC ACID ATOMS : 292 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 22 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 45.28 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 0.99000 REMARK 3 B22 (A**2) : 0.99000 REMARK 3 B33 (A**2) : -1.99000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): NULL REMARK 3 ESU BASED ON FREE R VALUE (A): 0.482 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.342 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 39.599 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.911 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.838 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1215 ; 0.005 ; 0.022 REMARK 3 BOND LENGTHS OTHERS (A): NULL ; NULL ; NULL REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 1710 ; 0.849 ; 2.267 REMARK 3 BOND ANGLES OTHERS (DEGREES): NULL ; NULL ; NULL REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 106 ; 4.093 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 43 ;34.897 ;25.581 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 154 ;13.561 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 2 ; 3.325 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 203 ; 0.052 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 812 ; 0.003 ; 0.021 REMARK 3 GENERAL PLANES OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 539 ; 0.149 ; 1.500 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 873 ; 0.276 ; 2.000 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 676 ; 0.262 ; 3.000 REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): 837 ; 0.475 ; 4.500 REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 2 REMARK 3 REMARK 3 TLS GROUP : 1 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : X -10 X 9999 REMARK 3 ORIGIN FOR THE GROUP (A): 11.5260 24.5026 63.0806 REMARK 3 T TENSOR REMARK 3 T11: 0.1367 T22: 0.2637 REMARK 3 T33: 0.1072 T12: 0.0317 REMARK 3 T13: -0.0308 T23: 0.0224 REMARK 3 L TENSOR REMARK 3 L11: 3.9793 L22: 6.3147 REMARK 3 L33: 4.0483 L12: 0.8355 REMARK 3 L13: 0.1705 L23: 1.2893 REMARK 3 S TENSOR REMARK 3 S11: 0.0894 S12: -0.2480 S13: 0.0087 REMARK 3 S21: 0.1663 S22: -0.0341 S23: 0.2260 REMARK 3 S31: 0.0816 S32: -0.3412 S33: -0.0553 REMARK 3 REMARK 3 TLS GROUP : 2 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : A -10 A 9999 REMARK 3 ORIGIN FOR THE GROUP (A): 32.4843 36.9191 58.8317 REMARK 3 T TENSOR REMARK 3 T11: 0.3922 T22: 0.3263 REMARK 3 T33: 0.4239 T12: -0.0345 REMARK 3 T13: -0.0259 T23: -0.1100 REMARK 3 L TENSOR REMARK 3 L11: 2.3738 L22: 0.9076 REMARK 3 L33: 1.8492 L12: -0.6935 REMARK 3 L13: -1.6449 L23: 0.0647 REMARK 3 S TENSOR REMARK 3 S11: 0.0686 S12: -0.3239 S13: 0.3400 REMARK 3 S21: 0.2653 S22: 0.1628 S23: -0.3570 REMARK 3 S31: 0.0628 S32: 0.1239 S33: -0.2314 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.40 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS REMARK 4 REMARK 4 3O3I COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 27-JUL-10. REMARK 100 THE DEPOSITION ID IS D_1000060618. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 19-JUN-10 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 4.6 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : APS REMARK 200 BEAMLINE : 24-ID-C REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9792 REMARK 200 MONOCHROMATOR : CRYO-COOLED SI(111) DOUBLE REMARK 200 CRYSTAL. REMARK 200 OPTICS : CRYOGENICALLY-COOLED DOUBLE REMARK 200 CRYSTAL SI(111) MONOCHROMATOR. REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 315 REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO, HKL-2000 REMARK 200 DATA SCALING SOFTWARE : SCALEPACK, HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 3966 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.800 REMARK 200 RESOLUTION RANGE LOW (A) : 20.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 96.6 REMARK 200 DATA REDUNDANCY : 4.100 REMARK 200 R MERGE (I) : 0.09600 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 14.8000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.80 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.90 REMARK 200 COMPLETENESS FOR SHELL (%) : 78.7 REMARK 200 DATA REDUNDANCY IN SHELL : 2.80 REMARK 200 R MERGE FOR SHELL (I) : 0.36100 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 1.900 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL REMARK 200 SOFTWARE USED: DIFFERENCE FOURIER REMARK 200 STARTING MODEL: HIWI1(V361M)PAZ DOMAIN REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 35.66 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 1.91 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 1-5% PEG3350, 50 MM NACL, 50 MM NA REMARK 280 -ACETATE BUFFER, PH 4.6, VAPOR DIFFUSION, HANGING DROP, REMARK 280 TEMPERATURE 277K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 41 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -Y,X,Z+1/4 REMARK 290 4555 Y,-X,Z+3/4 REMARK 290 5555 -X,Y,-Z REMARK 290 6555 X,-Y,-Z+1/2 REMARK 290 7555 Y,X,-Z+3/4 REMARK 290 8555 -Y,-X,-Z+1/4 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 73.85350 REMARK 290 SMTRY1 3 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 36.92675 REMARK 290 SMTRY1 4 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 110.78025 REMARK 290 SMTRY1 5 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 6 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 -1.000000 73.85350 REMARK 290 SMTRY1 7 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 7 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 110.78025 REMARK 290 SMTRY1 8 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 36.92675 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 5250 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 14920 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -36.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: X, A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMT1 2 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT2 2 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT3 2 0.000000 0.000000 -1.000000 110.78025 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 ARG X 368 REMARK 465 ARG X 369 REMARK 465 ARG X 370 REMARK 465 GLY X 371 REMARK 465 PRO X 372 REMARK 465 GLY X 373 REMARK 465 GLY X 374 REMARK 465 THR X 375 REMARK 465 LEU X 376 REMARK 465 PRO X 377 REMARK 465 ASP X 394 REMARK 465 LYS X 395 REMARK 465 MET X 396 REMARK 465 ARG X 397 REMARK 465 ASN X 398 REMARK 465 ASP X 399 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 SER X 276 OG REMARK 470 PHE X 286 CG CD1 CD2 CE1 CE2 CZ REMARK 470 GLN X 298 CD OE1 NE2 REMARK 470 LYS X 301 CG CD CE NZ REMARK 470 GLU X 302 CG CD OE1 OE2 REMARK 470 GLU X 339 CG CD OE1 OE2 REMARK 470 LEU X 392 CG CD1 CD2 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASN X 314 46.72 -73.33 REMARK 500 REMARK 500 REMARK: NULL DBREF 3O3I X 277 399 UNP Q96J94 PIWL1_HUMAN 277 399 DBREF 3O3I A 1 14 PDB 3O3I 3O3I 1 14 SEQADV 3O3I SER X 276 UNP Q96J94 EXPRESSION TAG SEQRES 1 X 124 SER GLU THR VAL LEU ASP PHE MET PHE ASN PHE TYR HIS SEQRES 2 X 124 GLN THR GLU GLU HIS LYS PHE GLN GLU GLN VAL SER LYS SEQRES 3 X 124 GLU LEU ILE GLY LEU VAL VAL LEU THR LYS TYR ASN ASN SEQRES 4 X 124 LYS THR TYR ARG VAL ASP ASP ILE ASP TRP ASP GLN ASN SEQRES 5 X 124 PRO LYS SER THR PHE LYS LYS ALA ASP GLY SER GLU VAL SEQRES 6 X 124 SER PHE LEU GLU TYR TYR ARG LYS GLN TYR ASN GLN GLU SEQRES 7 X 124 ILE THR ASP LEU LYS GLN PRO VAL LEU VAL SER GLN PRO SEQRES 8 X 124 LYS ARG ARG ARG GLY PRO GLY GLY THR LEU PRO GLY PRO SEQRES 9 X 124 ALA MET LEU ILE PRO GLU LEU CYS TYR LEU THR GLY LEU SEQRES 10 X 124 THR ASP LYS MET ARG ASN ASP SEQRES 1 A 14 G C G A A U A U U C G C U SEQRES 2 A 14 U FORMUL 3 HOH *22(H2 O) HELIX 1 1 THR X 278 PHE X 284 1 7 HELIX 2 2 GLU X 291 ILE X 304 1 14 HELIX 3 3 PHE X 342 ASN X 351 1 10 SHEET 1 A 3 THR X 316 ARG X 318 0 SHEET 2 A 3 VAL X 307 THR X 310 -1 N VAL X 308 O TYR X 317 SHEET 3 A 3 CYS X 387 TYR X 388 -1 O TYR X 388 N LEU X 309 SHEET 1 B 3 ASP X 321 ASP X 323 0 SHEET 2 B 3 VAL X 361 SER X 364 -1 O VAL X 361 N ASP X 323 SHEET 3 B 3 ALA X 380 LEU X 382 -1 O LEU X 382 N LEU X 362 SHEET 1 C 2 THR X 331 LYS X 333 0 SHEET 2 C 2 GLU X 339 SER X 341 -1 O VAL X 340 N PHE X 332 CRYST1 44.303 44.303 147.707 90.00 90.00 90.00 P 41 2 2 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.022572 0.000000 0.000000 0.00000 SCALE2 0.000000 0.022572 0.000000 0.00000 SCALE3 0.000000 0.000000 0.006770 0.00000 ATOM 1 N SER X 276 26.046 16.199 63.854 1.00 53.93 N ANISOU 1 N SER X 276 5545 6554 8391 1538 -1649 -256 N ATOM 2 CA SER X 276 24.856 16.456 64.716 1.00 51.99 C ANISOU 2 CA SER X 276 5635 6383 7736 1386 -1740 -18 C ATOM 3 C SER X 276 23.582 16.595 63.878 1.00 49.10 C ANISOU 3 C SER X 276 5467 6056 7132 1208 -1433 0 C ATOM 4 O SER X 276 23.425 17.559 63.123 1.00 47.33 O ANISOU 4 O SER X 276 5167 5972 6843 1092 -1186 -114 O ATOM 5 CB SER X 276 25.078 17.706 65.572 1.00 51.57 C ANISOU 5 CB SER X 276 5520 6536 7537 1295 -1852 -14 C ATOM 6 N GLU X 277 22.682 15.623 64.016 1.00 49.07 N ANISOU 6 N GLU X 277 5718 5914 7009 1182 -1470 152 N ATOM 7 CA GLU X 277 21.447 15.581 63.228 1.00 46.93 C ANISOU 7 CA GLU X 277 5607 5665 6556 1019 -1235 159 C ATOM 8 C GLU X 277 20.488 16.716 63.581 1.00 44.50 C ANISOU 8 C GLU X 277 5377 5577 5953 845 -1146 233 C ATOM 9 O GLU X 277 20.406 17.140 64.736 1.00 44.69 O ANISOU 9 O GLU X 277 5463 5687 5830 819 -1284 348 O ATOM 10 CB GLU X 277 20.746 14.223 63.367 1.00 48.13 C ANISOU 10 CB GLU X 277 5991 5597 6699 1006 -1308 293 C ATOM 11 CG GLU X 277 20.405 13.824 64.800 1.00 49.71 C ANISOU 11 CG GLU X 277 6401 5743 6743 982 -1539 552 C ATOM 12 CD GLU X 277 19.318 12.765 64.887 1.00 50.79 C ANISOU 12 CD GLU X 277 6800 5705 6791 853 -1514 706 C ATOM 13 OE1 GLU X 277 18.526 12.625 63.928 1.00 49.60 O ANISOU 13 OE1 GLU X 277 6658 5554 6631 732 -1316 611 O ATOM 14 OE2 GLU X 277 19.253 12.076 65.929 1.00 53.06 O ANISOU 14 OE2 GLU X 277 7299 5850 7009 856 -1704 929 O ATOM 15 N THR X 278 19.771 17.201 62.572 1.00 42.65 N ANISOU 15 N THR X 278 5148 5426 5629 737 -925 155 N ATOM 16 CA THR X 278 18.821 18.294 62.750 1.00 40.71 C ANISOU 16 CA THR X 278 4947 5361 5160 607 -835 202 C ATOM 17 C THR X 278 17.440 17.758 63.126 1.00 40.52 C ANISOU 17 C THR X 278 5088 5330 4975 491 -834 339 C ATOM 18 O THR X 278 17.206 16.548 63.080 1.00 41.72 O ANISOU 18 O THR X 278 5341 5326 5185 481 -883 396 O ATOM 19 CB THR X 278 18.721 19.180 61.484 1.00 39.44 C ANISOU 19 CB THR X 278 4717 5283 4982 561 -636 74 C ATOM 20 OG1 THR X 278 18.229 18.404 60.386 1.00 39.54 O ANISOU 20 OG1 THR X 278 4804 5217 4999 530 -553 24 O ATOM 21 CG2 THR X 278 20.082 19.766 61.122 1.00 40.03 C ANISOU 21 CG2 THR X 278 4618 5368 5222 627 -577 -63 C ATOM 22 N VAL X 279 16.536 18.661 63.502 1.00 39.43 N ANISOU 22 N VAL X 279 4963 5348 4667 398 -763 378 N ATOM 23 CA VAL X 279 15.163 18.289 63.856 1.00 39.65 C ANISOU 23 CA VAL X 279 5083 5407 4572 267 -715 479 C ATOM 24 C VAL X 279 14.424 17.722 62.638 1.00 39.56 C ANISOU 24 C VAL X 279 5064 5343 4624 202 -649 424 C ATOM 25 O VAL X 279 13.609 16.805 62.769 1.00 40.48 O ANISOU 25 O VAL X 279 5252 5387 4738 90 -650 493 O ATOM 26 CB VAL X 279 14.389 19.481 64.484 1.00 38.97 C ANISOU 26 CB VAL X 279 4963 5506 4335 212 -627 484 C ATOM 27 CG1 VAL X 279 12.952 19.095 64.827 1.00 39.63 C ANISOU 27 CG1 VAL X 279 5078 5640 4338 69 -534 558 C ATOM 28 CG2 VAL X 279 15.102 19.977 65.729 1.00 39.46 C ANISOU 28 CG2 VAL X 279 5076 5618 4298 253 -708 513 C ATOM 29 N LEU X 280 14.732 18.262 61.459 1.00 38.86 N ANISOU 29 N LEU X 280 4906 5283 4576 250 -595 297 N ATOM 30 CA LEU X 280 14.185 17.759 60.201 1.00 39.30 C ANISOU 30 CA LEU X 280 4987 5294 4648 194 -566 218 C ATOM 31 C LEU X 280 14.672 16.338 59.917 1.00 40.95 C ANISOU 31 C LEU X 280 5281 5296 4982 209 -608 179 C ATOM 32 O LEU X 280 13.892 15.488 59.484 1.00 41.90 O ANISOU 32 O LEU X 280 5468 5335 5116 104 -625 162 O ATOM 33 CB LEU X 280 14.540 18.695 59.039 1.00 38.56 C ANISOU 33 CB LEU X 280 4865 5272 4511 239 -493 109 C ATOM 34 CG LEU X 280 13.997 18.356 57.643 1.00 39.08 C ANISOU 34 CG LEU X 280 5004 5325 4517 179 -484 17 C ATOM 35 CD1 LEU X 280 12.487 18.553 57.559 1.00 38.98 C ANISOU 35 CD1 LEU X 280 4962 5413 4435 84 -558 67 C ATOM 36 CD2 LEU X 280 14.705 19.176 56.579 1.00 38.91 C ANISOU 36 CD2 LEU X 280 5021 5343 4419 222 -386 -68 C ATOM 37 N ASP X 281 15.960 16.094 60.164 1.00 41.84 N ANISOU 37 N ASP X 281 5373 5309 5215 341 -635 148 N ATOM 38 CA ASP X 281 16.548 14.759 60.037 1.00 44.06 C ANISOU 38 CA ASP X 281 5720 5351 5667 408 -691 108 C ATOM 39 C ASP X 281 15.869 13.779 60.989 1.00 45.61 C ANISOU 39 C ASP X 281 6053 5410 5866 324 -797 281 C ATOM 40 O ASP X 281 15.577 12.644 60.616 1.00 47.17 O ANISOU 40 O ASP X 281 6359 5404 6157 274 -817 256 O ATOM 41 CB ASP X 281 18.054 14.797 60.323 1.00 44.86 C ANISOU 41 CB ASP X 281 5712 5389 5943 596 -734 53 C ATOM 42 CG ASP X 281 18.844 15.551 59.263 1.00 44.54 C ANISOU 42 CG ASP X 281 5540 5440 5942 648 -571 -139 C ATOM 43 OD1 ASP X 281 18.263 15.959 58.233 1.00 43.83 O ANISOU 43 OD1 ASP X 281 5501 5439 5711 551 -440 -217 O ATOM 44 OD2 ASP X 281 20.062 15.734 59.467 1.00 45.23 O ANISOU 44 OD2 ASP X 281 5472 5512 6202 778 -579 -210 O ATOM 45 N PHE X 282 15.619 14.242 62.213 1.00 45.71 N ANISOU 45 N PHE X 282 6082 5524 5761 289 -848 449 N ATOM 46 CA PHE X 282 14.933 13.469 63.246 1.00 47.69 C ANISOU 46 CA PHE X 282 6494 5676 5948 169 -905 646 C ATOM 47 C PHE X 282 13.523 13.050 62.821 1.00 48.31 C ANISOU 47 C PHE X 282 6604 5757 5993 -49 -805 647 C ATOM 48 O PHE X 282 13.124 11.906 63.041 1.00 50.34 O ANISOU 48 O PHE X 282 7007 5806 6314 -161 -832 736 O ATOM 49 CB PHE X 282 14.881 14.282 64.545 1.00 47.39 C ANISOU 49 CB PHE X 282 6476 5810 5720 153 -927 783 C ATOM 50 CG PHE X 282 14.193 13.582 65.687 1.00 49.59 C ANISOU 50 CG PHE X 282 6960 6014 5866 2 -940 1002 C ATOM 51 CD1 PHE X 282 14.885 12.671 66.483 1.00 52.14 C ANISOU 51 CD1 PHE X 282 7486 6118 6207 71 -1120 1170 C ATOM 52 CD2 PHE X 282 12.857 13.846 65.977 1.00 49.63 C ANISOU 52 CD2 PHE X 282 6958 6164 5733 -208 -768 1045 C ATOM 53 CE1 PHE X 282 14.255 12.027 67.545 1.00 54.56 C ANISOU 53 CE1 PHE X 282 8044 6342 6345 -95 -1116 1405 C ATOM 54 CE2 PHE X 282 12.216 13.206 67.035 1.00 52.09 C ANISOU 54 CE2 PHE X 282 7470 6416 5906 -387 -720 1246 C ATOM 55 CZ PHE X 282 12.917 12.296 67.822 1.00 54.59 C ANISOU 55 CZ PHE X 282 8047 6504 6188 -344 -887 1441 C ATOM 56 N MET X 283 12.786 13.978 62.211 1.00 47.16 N ANISOU 56 N MET X 283 6315 5832 5772 -111 -709 548 N ATOM 57 CA MET X 283 11.396 13.751 61.791 1.00 48.17 C ANISOU 57 CA MET X 283 6397 6011 5894 -311 -648 524 C ATOM 58 C MET X 283 11.213 12.567 60.846 1.00 50.05 C ANISOU 58 C MET X 283 6715 6036 6264 -392 -693 424 C ATOM 59 O MET X 283 10.178 11.898 60.876 1.00 51.73 O ANISOU 59 O MET X 283 6939 6192 6521 -601 -676 449 O ATOM 60 CB MET X 283 10.824 15.005 61.132 1.00 46.51 C ANISOU 60 CB MET X 283 6009 6048 5612 -293 -604 420 C ATOM 61 CG MET X 283 10.440 16.095 62.100 1.00 45.89 C ANISOU 61 CG MET X 283 5838 6169 5428 -284 -527 495 C ATOM 62 SD MET X 283 9.953 17.591 61.231 1.00 44.81 S ANISOU 62 SD MET X 283 5523 6245 5258 -202 -515 379 S ATOM 63 CE MET X 283 9.675 18.690 62.615 1.00 44.72 C ANISOU 63 CE MET X 283 5439 6395 5155 -174 -404 444 C ATOM 64 N PHE X 284 12.213 12.318 60.007 1.00 50.41 N ANISOU 64 N PHE X 284 6806 5964 6384 -242 -730 287 N ATOM 65 CA PHE X 284 12.148 11.232 59.035 1.00 52.64 C ANISOU 65 CA PHE X 284 7188 6032 6780 -299 -759 138 C ATOM 66 C PHE X 284 13.103 10.079 59.369 1.00 54.75 C ANISOU 66 C PHE X 284 7609 5968 7226 -189 -812 162 C ATOM 67 O PHE X 284 13.399 9.241 58.514 1.00 56.40 O ANISOU 67 O PHE X 284 7905 5967 7557 -165 -818 -11 O ATOM 68 CB PHE X 284 12.392 11.771 57.620 1.00 51.99 C ANISOU 68 CB PHE X 284 7064 6062 6625 -233 -729 -83 C ATOM 69 CG PHE X 284 11.308 12.700 57.127 1.00 51.52 C ANISOU 69 CG PHE X 284 6892 6264 6417 -341 -742 -103 C ATOM 70 CD1 PHE X 284 10.172 12.194 56.491 1.00 53.32 C ANISOU 70 CD1 PHE X 284 7121 6488 6648 -532 -817 -187 C ATOM 71 CD2 PHE X 284 11.422 14.080 57.295 1.00 49.81 C ANISOU 71 CD2 PHE X 284 6561 6278 6084 -245 -706 -45 C ATOM 72 CE1 PHE X 284 9.166 13.048 56.031 1.00 53.04 C ANISOU 72 CE1 PHE X 284 6951 6689 6511 -599 -883 -205 C ATOM 73 CE2 PHE X 284 10.420 14.944 56.838 1.00 49.53 C ANISOU 73 CE2 PHE X 284 6424 6448 5947 -305 -750 -54 C ATOM 74 CZ PHE X 284 9.291 14.426 56.206 1.00 51.10 C ANISOU 74 CZ PHE X 284 6600 6655 6158 -468 -852 -130 C ATOM 75 N ASN X 285 13.566 10.042 60.619 1.00 55.29 N ANISOU 75 N ASN X 285 7722 5982 7303 -115 -866 369 N ATOM 76 CA ASN X 285 14.446 8.977 61.109 1.00 57.92 C ANISOU 76 CA ASN X 285 8207 5982 7816 18 -976 444 C ATOM 77 C ASN X 285 13.957 8.326 62.403 1.00 59.99 C ANISOU 77 C ASN X 285 8661 6092 8040 -114 -1044 734 C ATOM 78 O ASN X 285 14.178 7.132 62.620 1.00 62.87 O ANISOU 78 O ASN X 285 9224 6099 8565 -103 -1135 814 O ATOM 79 CB ASN X 285 15.877 9.491 61.306 1.00 57.40 C ANISOU 79 CB ASN X 285 8031 5955 7821 303 -1040 409 C ATOM 80 CG ASN X 285 16.621 9.704 59.993 1.00 57.26 C ANISOU 80 CG ASN X 285 7882 5963 7911 441 -942 114 C ATOM 81 OD1 ASN X 285 16.428 8.970 59.019 1.00 58.72 O ANISOU 81 OD1 ASN X 285 8139 5988 8181 400 -883 -65 O ATOM 82 ND2 ASN X 285 17.493 10.707 59.970 1.00 56.13 N ANISOU 82 ND2 ASN X 285 7558 6015 7753 586 -907 53 N ATOM 83 N PHE X 286 13.304 9.116 63.257 1.00 59.04 N ANISOU 83 N PHE X 286 8503 6226 7701 -240 -984 889 N ATOM 84 CA PHE X 286 12.824 8.643 64.560 1.00 61.27 C ANISOU 84 CA PHE X 286 8994 6417 7869 -397 -995 1174 C ATOM 85 C PHE X 286 11.693 7.628 64.422 1.00 63.69 C ANISOU 85 C PHE X 286 9422 6528 8247 -695 -906 1224 C ATOM 86 O PHE X 286 11.835 6.476 64.840 1.00 66.82 O ANISOU 86 O PHE X 286 10077 6570 8741 -743 -984 1382 O ATOM 87 CB PHE X 286 12.373 9.815 65.433 1.00 59.77 C ANISOU 87 CB PHE X 286 8720 6574 7413 -467 -897 1267 C ATOM 88 N TYR X 287 10.574 8.061 63.844 1.00 62.67 N ANISOU 88 N TYR X 287 9103 6615 8092 -896 -762 1092 N ATOM 89 CA TYR X 287 9.462 7.156 63.570 1.00 65.10 C ANISOU 89 CA TYR X 287 9454 6765 8512 -1206 -684 1083 C ATOM 90 C TYR X 287 8.922 7.325 62.154 1.00 64.11 C ANISOU 90 C TYR X 287 9120 6746 8492 -1259 -686 787 C ATOM 91 O TYR X 287 8.682 8.446 61.692 1.00 61.67 O ANISOU 91 O TYR X 287 8576 6766 8087 -1191 -659 662 O ATOM 92 CB TYR X 287 8.346 7.303 64.610 1.00 66.51 C ANISOU 92 CB TYR X 287 9626 7087 8554 -1499 -501 1272 C ATOM 93 CG TYR X 287 7.550 6.029 64.809 1.00 70.47 C ANISOU 93 CG TYR X 287 10299 7288 9186 -1834 -428 1380 C ATOM 94 CD1 TYR X 287 8.083 4.958 65.530 1.00 73.47 C ANISOU 94 CD1 TYR X 287 11053 7273 9586 -1852 -498 1625 C ATOM 95 CD2 TYR X 287 6.270 5.891 64.272 1.00 71.61 C ANISOU 95 CD2 TYR X 287 10230 7522 9454 -2138 -310 1241 C ATOM 96 CE1 TYR X 287 7.361 3.782 65.713 1.00 77.51 C ANISOU 96 CE1 TYR X 287 11759 7463 10229 -2186 -418 1741 C ATOM 97 CE2 TYR X 287 5.537 4.717 64.451 1.00 75.61 C ANISOU 97 CE2 TYR X 287 10880 7736 10110 -2488 -228 1328 C ATOM 98 CZ TYR X 287 6.090 3.668 65.172 1.00 78.58 C ANISOU 98 CZ TYR X 287 11664 7697 10494 -2521 -266 1584 C ATOM 99 OH TYR X 287 5.374 2.505 65.355 1.00 82.86 O ANISOU 99 OH TYR X 287 12382 7908 11192 -2892 -173 1687 O ATOM 100 N HIS X 288 8.743 6.193 61.480 1.00 66.46 N ANISOU 100 N HIS X 288 9535 6739 8976 -1381 -737 680 N ATOM 101 CA HIS X 288 8.320 6.148 60.086 1.00 66.38 C ANISOU 101 CA HIS X 288 9401 6776 9041 -1439 -785 382 C ATOM 102 C HIS X 288 6.846 5.751 60.009 1.00 68.61 C ANISOU 102 C HIS X 288 9575 7085 9408 -1820 -734 354 C ATOM 103 O HIS X 288 6.449 4.703 60.526 1.00 71.78 O ANISOU 103 O HIS X 288 10136 7196 9940 -2058 -690 473 O ATOM 104 CB HIS X 288 9.187 5.151 59.306 1.00 67.97 C ANISOU 104 CB HIS X 288 9809 6612 9404 -1309 -878 214 C ATOM 105 CG HIS X 288 10.641 5.518 59.249 1.00 66.44 C ANISOU 105 CG HIS X 288 9649 6403 9191 -937 -913 186 C ATOM 106 ND1 HIS X 288 11.425 5.272 58.142 1.00 66.94 N ANISOU 106 ND1 HIS X 288 9747 6353 9330 -758 -937 -85 N ATOM 107 CD2 HIS X 288 11.452 6.112 60.157 1.00 65.02 C ANISOU 107 CD2 HIS X 288 9453 6315 8934 -726 -923 373 C ATOM 108 CE1 HIS X 288 12.656 5.695 58.372 1.00 65.70 C ANISOU 108 CE1 HIS X 288 9558 6221 9182 -455 -940 -62 C ATOM 109 NE2 HIS X 288 12.699 6.210 59.588 1.00 64.49 N ANISOU 109 NE2 HIS X 288 9370 6190 8941 -430 -958 214 N ATOM 110 N GLN X 289 6.043 6.599 59.368 1.00 67.34 N ANISOU 110 N GLN X 289 9132 7261 9189 -1878 -750 203 N ATOM 111 CA GLN X 289 4.595 6.409 59.307 1.00 69.51 C ANISOU 111 CA GLN X 289 9197 7633 9577 -2222 -719 153 C ATOM 112 C GLN X 289 4.023 6.859 57.964 1.00 69.18 C ANISOU 112 C GLN X 289 8948 7802 9535 -2232 -888 -126 C ATOM 113 O GLN X 289 4.296 7.971 57.504 1.00 66.56 O ANISOU 113 O GLN X 289 8502 7739 9046 -1997 -948 -183 O ATOM 114 CB GLN X 289 3.917 7.170 60.454 1.00 69.15 C ANISOU 114 CB GLN X 289 8951 7856 9467 -2309 -535 345 C ATOM 115 CG GLN X 289 2.435 6.860 60.646 1.00 72.55 C ANISOU 115 CG GLN X 289 9130 8364 10069 -2694 -433 318 C ATOM 116 CD GLN X 289 2.188 5.547 61.369 1.00 76.55 C ANISOU 116 CD GLN X 289 9862 8517 10705 -3019 -299 478 C ATOM 117 OE1 GLN X 289 2.873 5.215 62.338 1.00 76.86 O ANISOU 117 OE1 GLN X 289 10199 8367 10636 -2966 -198 726 O ATOM 118 NE2 GLN X 289 1.193 4.797 60.906 1.00 80.13 N ANISOU 118 NE2 GLN X 289 10184 8870 11391 -3369 -316 342 N ATOM 119 N THR X 290 3.227 5.989 57.345 1.00 72.26 N ANISOU 119 N THR X 290 9311 8052 10092 -2516 -980 -292 N ATOM 120 CA THR X 290 2.573 6.293 56.067 1.00 72.89 C ANISOU 120 CA THR X 290 9215 8320 10158 -2566 -1199 -563 C ATOM 121 C THR X 290 1.282 7.100 56.251 1.00 73.40 C ANISOU 121 C THR X 290 8851 8740 10296 -2699 -1219 -557 C ATOM 122 O THR X 290 0.864 7.828 55.347 1.00 73.16 O ANISOU 122 O THR X 290 8640 8960 10196 -2615 -1428 -710 O ATOM 123 CB THR X 290 2.309 5.012 55.222 1.00 76.56 C ANISOU 123 CB THR X 290 9839 8480 10768 -2814 -1337 -799 C ATOM 124 OG1 THR X 290 1.761 5.375 53.949 1.00 77.51 O ANISOU 124 OG1 THR X 290 9831 8810 10809 -2839 -1594 -1066 O ATOM 125 CG2 THR X 290 1.356 4.050 55.936 1.00 80.25 C ANISOU 125 CG2 THR X 290 10228 8749 11514 -3225 -1237 -727 C ATOM 126 N GLU X 291 0.662 6.958 57.421 1.00 74.48 N ANISOU 126 N GLU X 291 8836 8887 10573 -2899 -1000 -379 N ATOM 127 CA GLU X 291 -0.528 7.722 57.780 1.00 75.31 C ANISOU 127 CA GLU X 291 8495 9324 10794 -3008 -945 -378 C ATOM 128 C GLU X 291 -0.124 9.144 58.161 1.00 71.52 C ANISOU 128 C GLU X 291 7921 9128 10125 -2661 -881 -271 C ATOM 129 O GLU X 291 0.703 9.344 59.052 1.00 69.35 O ANISOU 129 O GLU X 291 7851 8794 9704 -2514 -693 -78 O ATOM 130 CB GLU X 291 -1.277 7.038 58.930 1.00 78.50 C ANISOU 130 CB GLU X 291 8800 9631 11394 -3371 -659 -238 C ATOM 131 CG GLU X 291 -2.497 7.797 59.458 1.00 80.31 C ANISOU 131 CG GLU X 291 8530 10205 11780 -3490 -513 -250 C ATOM 132 CD GLU X 291 -3.642 7.863 58.465 1.00 83.48 C ANISOU 132 CD GLU X 291 8507 10781 12428 -3642 -773 -518 C ATOM 133 OE1 GLU X 291 -4.136 8.981 58.212 1.00 82.90 O ANISOU 133 OE1 GLU X 291 8080 11034 12382 -3445 -882 -598 O ATOM 134 OE2 GLU X 291 -4.048 6.804 57.937 1.00 86.90 O ANISOU 134 OE2 GLU X 291 8964 11011 13041 -3952 -895 -654 O ATOM 135 N GLU X 292 -0.717 10.120 57.477 1.00 71.10 N ANISOU 135 N GLU X 292 7568 9362 10083 -2533 -1067 -399 N ATOM 136 CA GLU X 292 -0.355 11.531 57.627 1.00 67.84 C ANISOU 136 CA GLU X 292 7080 9183 9509 -2192 -1054 -329 C ATOM 137 C GLU X 292 -0.667 12.092 59.017 1.00 67.34 C ANISOU 137 C GLU X 292 6841 9255 9488 -2195 -738 -178 C ATOM 138 O GLU X 292 0.149 12.813 59.594 1.00 64.44 O ANISOU 138 O GLU X 292 6626 8923 8933 -1960 -618 -55 O ATOM 139 CB GLU X 292 -1.041 12.370 56.543 1.00 68.71 C ANISOU 139 CB GLU X 292 6926 9527 9651 -2069 -1363 -488 C ATOM 140 CG GLU X 292 -0.558 13.814 56.433 1.00 66.29 C ANISOU 140 CG GLU X 292 6626 9394 9168 -1701 -1405 -422 C ATOM 141 CD GLU X 292 0.870 13.930 55.923 1.00 63.99 C ANISOU 141 CD GLU X 292 6760 8967 8584 -1491 -1438 -379 C ATOM 142 OE1 GLU X 292 1.194 13.312 54.883 1.00 64.94 O ANISOU 142 OE1 GLU X 292 7096 8971 8606 -1536 -1620 -496 O ATOM 143 OE2 GLU X 292 1.667 14.651 56.563 1.00 61.53 O ANISOU 143 OE2 GLU X 292 6556 8671 8149 -1290 -1269 -249 O ATOM 144 N HIS X 293 -1.844 11.758 59.544 1.00 70.44 N ANISOU 144 N HIS X 293 6911 9728 10125 -2480 -591 -209 N ATOM 145 CA HIS X 293 -2.266 12.236 60.861 1.00 70.79 C ANISOU 145 CA HIS X 293 6779 9917 10200 -2526 -238 -102 C ATOM 146 C HIS X 293 -1.496 11.561 61.996 1.00 69.95 C ANISOU 146 C HIS X 293 7065 9600 9909 -2634 39 120 C ATOM 147 O HIS X 293 -1.186 12.198 63.005 1.00 68.74 O ANISOU 147 O HIS X 293 6980 9544 9592 -2520 266 241 O ATOM 148 CB HIS X 293 -3.774 12.051 61.052 1.00 75.36 C ANISOU 148 CB HIS X 293 6861 10652 11117 -2823 -123 -225 C ATOM 149 CG HIS X 293 -4.319 12.746 62.261 1.00 76.65 C ANISOU 149 CG HIS X 293 6776 11024 11323 -2834 257 -180 C ATOM 150 ND1 HIS X 293 -4.379 14.119 62.366 1.00 75.29 N ANISOU 150 ND1 HIS X 293 6399 11080 11124 -2501 256 -235 N ATOM 151 CD2 HIS X 293 -4.833 12.258 63.415 1.00 79.67 C ANISOU 151 CD2 HIS X 293 7104 11408 11757 -3146 674 -97 C ATOM 152 CE1 HIS X 293 -4.903 14.447 63.534 1.00 77.29 C ANISOU 152 CE1 HIS X 293 6471 11477 11419 -2595 660 -218 C ATOM 153 NE2 HIS X 293 -5.188 13.336 64.189 1.00 80.01 N ANISOU 153 NE2 HIS X 293 6907 11702 11791 -2994 931 -130 N ATOM 154 N LYS X 294 -1.195 10.274 61.822 1.00 70.80 N ANISOU 154 N LYS X 294 7450 9406 10042 -2848 -4 170 N ATOM 155 CA LYS X 294 -0.408 9.521 62.799 1.00 70.48 C ANISOU 155 CA LYS X 294 7832 9107 9837 -2929 180 407 C ATOM 156 C LYS X 294 1.056 9.952 62.822 1.00 66.24 C ANISOU 156 C LYS X 294 7633 8496 9037 -2559 64 502 C ATOM 157 O LYS X 294 1.703 9.900 63.868 1.00 65.76 O ANISOU 157 O LYS X 294 7837 8357 8790 -2516 211 705 O ATOM 158 CB LYS X 294 -0.512 8.016 62.552 1.00 73.45 C ANISOU 158 CB LYS X 294 8414 9128 10363 -3243 142 426 C ATOM 159 CG LYS X 294 -1.739 7.364 63.177 1.00 78.22 C ANISOU 159 CG LYS X 294 8820 9721 11178 -3704 408 457 C ATOM 160 CD LYS X 294 -1.700 5.846 63.037 1.00 81.48 C ANISOU 160 CD LYS X 294 9523 9707 11728 -4021 382 512 C ATOM 161 CE LYS X 294 -0.738 5.191 64.028 1.00 81.60 C ANISOU 161 CE LYS X 294 10073 9399 11531 -4006 511 827 C ATOM 162 NZ LYS X 294 -1.260 5.200 65.423 1.00 84.35 N ANISOU 162 NZ LYS X 294 10453 9822 11772 -4264 904 1060 N ATOM 163 N PHE X 295 1.569 10.372 61.667 1.00 63.48 N ANISOU 163 N PHE X 295 7273 8175 8668 -2310 -202 351 N ATOM 164 CA PHE X 295 2.918 10.924 61.572 1.00 59.60 C ANISOU 164 CA PHE X 295 7019 7656 7971 -1967 -294 399 C ATOM 165 C PHE X 295 3.016 12.219 62.372 1.00 57.55 C ANISOU 165 C PHE X 295 6647 7652 7565 -1782 -160 467 C ATOM 166 O PHE X 295 3.963 12.416 63.131 1.00 56.03 O ANISOU 166 O PHE X 295 6681 7409 7198 -1640 -102 603 O ATOM 167 CB PHE X 295 3.308 11.168 60.108 1.00 58.05 C ANISOU 167 CB PHE X 295 6819 7467 7770 -1787 -554 208 C ATOM 168 CG PHE X 295 4.636 11.861 59.936 1.00 54.62 C ANISOU 168 CG PHE X 295 6562 7038 7153 -1459 -607 233 C ATOM 169 CD1 PHE X 295 5.826 11.140 59.990 1.00 53.99 C ANISOU 169 CD1 PHE X 295 6781 6698 7034 -1366 -629 283 C ATOM 170 CD2 PHE X 295 4.696 13.236 59.719 1.00 52.31 C ANISOU 170 CD2 PHE X 295 6121 6991 6764 -1247 -635 197 C ATOM 171 CE1 PHE X 295 7.053 11.777 59.834 1.00 51.47 C ANISOU 171 CE1 PHE X 295 6565 6397 6593 -1085 -662 283 C ATOM 172 CE2 PHE X 295 5.919 13.882 59.563 1.00 49.69 C ANISOU 172 CE2 PHE X 295 5937 6654 6287 -988 -661 214 C ATOM 173 CZ PHE X 295 7.099 13.151 59.620 1.00 49.32 C ANISOU 173 CZ PHE X 295 6144 6380 6214 -917 -666 248 C ATOM 174 N GLN X 296 2.024 13.088 62.199 1.00 57.78 N ANISOU 174 N GLN X 296 6320 7944 7688 -1780 -132 355 N ATOM 175 CA GLN X 296 2.010 14.395 62.850 1.00 56.23 C ANISOU 175 CA GLN X 296 5995 7977 7394 -1592 -7 368 C ATOM 176 C GLN X 296 1.780 14.317 64.358 1.00 57.66 C ANISOU 176 C GLN X 296 6231 8199 7476 -1740 310 503 C ATOM 177 O GLN X 296 2.299 15.146 65.103 1.00 56.26 O ANISOU 177 O GLN X 296 6143 8116 7116 -1573 407 552 O ATOM 178 CB GLN X 296 0.982 15.319 62.190 1.00 56.97 C ANISOU 178 CB GLN X 296 5683 8302 7659 -1516 -92 199 C ATOM 179 CG GLN X 296 1.396 15.802 60.801 1.00 55.29 C ANISOU 179 CG GLN X 296 5496 8087 7423 -1295 -410 102 C ATOM 180 CD GLN X 296 0.431 16.807 60.195 1.00 56.54 C ANISOU 180 CD GLN X 296 5293 8453 7734 -1174 -548 -24 C ATOM 181 OE1 GLN X 296 -0.602 17.136 60.781 1.00 58.93 O ANISOU 181 OE1 GLN X 296 5260 8911 8218 -1241 -403 -74 O ATOM 182 NE2 GLN X 296 0.766 17.299 59.008 1.00 55.42 N ANISOU 182 NE2 GLN X 296 5225 8310 7521 -988 -829 -77 N ATOM 183 N GLU X 297 1.010 13.324 64.802 1.00 60.74 N ANISOU 183 N GLU X 297 6592 8515 7969 -2074 478 557 N ATOM 184 CA GLU X 297 0.766 13.128 66.233 1.00 62.79 C ANISOU 184 CA GLU X 297 6968 8801 8085 -2268 816 708 C ATOM 185 C GLU X 297 1.977 12.505 66.937 1.00 61.85 C ANISOU 185 C GLU X 297 7352 8447 7700 -2236 783 940 C ATOM 186 O GLU X 297 2.270 12.842 68.084 1.00 62.35 O ANISOU 186 O GLU X 297 7602 8576 7509 -2224 959 1063 O ATOM 187 CB GLU X 297 -0.522 12.320 66.488 1.00 67.25 C ANISOU 187 CB GLU X 297 7321 9370 8859 -2676 1051 695 C ATOM 188 CG GLU X 297 -0.430 10.815 66.225 1.00 69.36 C ANISOU 188 CG GLU X 297 7830 9307 9213 -2949 976 805 C ATOM 189 CD GLU X 297 -1.741 10.074 66.469 1.00 74.46 C ANISOU 189 CD GLU X 297 8236 9956 10098 -3396 1230 778 C ATOM 190 OE1 GLU X 297 -1.705 9.002 67.113 1.00 77.19 O ANISOU 190 OE1 GLU X 297 8889 10054 10385 -3693 1391 978 O ATOM 191 OE2 GLU X 297 -2.804 10.552 66.016 1.00 75.94 O ANISOU 191 OE2 GLU X 297 7922 10379 10552 -3455 1260 562 O ATOM 192 N GLN X 298 2.676 11.612 66.237 1.00 60.80 N ANISOU 192 N GLN X 298 7434 8037 7628 -2208 543 983 N ATOM 193 CA GLN X 298 3.865 10.944 66.770 1.00 60.29 C ANISOU 193 CA GLN X 298 7811 7709 7386 -2131 446 1190 C ATOM 194 C GLN X 298 5.046 11.912 66.860 1.00 56.70 C ANISOU 194 C GLN X 298 7443 7347 6754 -1770 299 1178 C ATOM 195 O GLN X 298 5.762 11.935 67.864 1.00 57.03 O ANISOU 195 O GLN X 298 7755 7346 6566 -1707 310 1347 O ATOM 196 CB GLN X 298 4.229 9.728 65.911 1.00 60.92 C ANISOU 196 CB GLN X 298 8049 7449 7647 -2180 243 1186 C ATOM 197 CG GLN X 298 5.253 8.792 66.536 1.00 62.13 C ANISOU 197 CG GLN X 298 8644 7265 7696 -2141 151 1420 C ATOM 198 N VAL X 299 5.235 12.702 65.803 1.00 53.59 N ANISOU 198 N VAL X 299 6828 7073 6459 -1552 150 982 N ATOM 199 CA VAL X 299 6.268 13.740 65.752 1.00 50.30 C ANISOU 199 CA VAL X 299 6437 6754 5919 -1242 37 938 C ATOM 200 C VAL X 299 6.031 14.796 66.836 1.00 50.19 C ANISOU 200 C VAL X 299 6373 6974 5720 -1214 219 956 C ATOM 201 O VAL X 299 6.968 15.219 67.514 1.00 49.30 O ANISOU 201 O VAL X 299 6442 6868 5421 -1069 170 1023 O ATOM 202 CB VAL X 299 6.349 14.381 64.334 1.00 47.98 C ANISOU 202 CB VAL X 299 5937 6535 5757 -1069 -118 738 C ATOM 203 CG1 VAL X 299 7.030 15.744 64.363 1.00 45.41 C ANISOU 203 CG1 VAL X 299 5563 6365 5324 -814 -150 679 C ATOM 204 CG2 VAL X 299 7.066 13.445 63.368 1.00 47.67 C ANISOU 204 CG2 VAL X 299 6044 6252 5815 -1026 -299 701 C ATOM 205 N SER X 300 4.772 15.199 66.994 1.00 51.48 N ANISOU 205 N SER X 300 6277 7326 5954 -1354 425 872 N ATOM 206 CA SER X 300 4.358 16.118 68.053 1.00 52.24 C ANISOU 206 CA SER X 300 6312 7639 5894 -1357 663 849 C ATOM 207 C SER X 300 4.640 15.554 69.448 1.00 54.38 C ANISOU 207 C SER X 300 6928 7852 5879 -1516 815 1051 C ATOM 208 O SER X 300 5.115 16.274 70.326 1.00 54.30 O ANISOU 208 O SER X 300 7061 7946 5622 -1418 869 1062 O ATOM 209 CB SER X 300 2.870 16.460 67.905 1.00 54.29 C ANISOU 209 CB SER X 300 6181 8090 6356 -1491 874 702 C ATOM 210 OG SER X 300 2.323 16.975 69.107 1.00 56.82 O ANISOU 210 OG SER X 300 6474 8586 6528 -1580 1200 686 O ATOM 211 N LYS X 301 4.350 14.269 69.643 1.00 56.58 N ANISOU 211 N LYS X 301 7370 7950 6177 -1771 869 1213 N ATOM 212 CA LYS X 301 4.577 13.608 70.929 1.00 59.22 C ANISOU 212 CA LYS X 301 8098 8188 6215 -1948 995 1456 C ATOM 213 C LYS X 301 6.065 13.461 71.241 1.00 57.67 C ANISOU 213 C LYS X 301 8259 7827 5826 -1729 695 1602 C ATOM 214 O LYS X 301 6.477 13.596 72.395 1.00 59.28 O ANISOU 214 O LYS X 301 8759 8067 5697 -1742 730 1740 O ATOM 215 CB LYS X 301 3.894 12.237 70.963 1.00 62.65 C ANISOU 215 CB LYS X 301 8634 8413 6755 -2291 1115 1609 C ATOM 216 N GLU X 302 6.859 13.194 70.207 1.00 54.83 N ANISOU 216 N GLU X 302 7859 7298 5676 -1529 398 1553 N ATOM 217 CA GLU X 302 8.295 12.969 70.361 1.00 53.62 C ANISOU 217 CA GLU X 302 7961 6971 5439 -1303 97 1660 C ATOM 218 C GLU X 302 9.082 14.258 70.587 1.00 51.05 C ANISOU 218 C GLU X 302 7566 6844 4984 -1053 1 1539 C ATOM 219 O GLU X 302 10.049 14.268 71.350 1.00 51.81 O ANISOU 219 O GLU X 302 7905 6892 4888 -944 -172 1653 O ATOM 220 CB GLU X 302 8.855 12.221 69.148 1.00 52.31 C ANISOU 220 CB GLU X 302 7747 6556 5569 -1183 -128 1606 C ATOM 221 N LEU X 303 8.664 15.340 69.932 1.00 48.34 N ANISOU 221 N LEU X 303 6902 6706 4757 -969 90 1312 N ATOM 222 CA LEU X 303 9.428 16.590 69.945 1.00 45.79 C ANISOU 222 CA LEU X 303 6498 6523 4375 -741 -4 1176 C ATOM 223 C LEU X 303 9.021 17.596 71.019 1.00 46.70 C ANISOU 223 C LEU X 303 6637 6866 4241 -781 189 1118 C ATOM 224 O LEU X 303 9.889 18.227 71.624 1.00 46.49 O ANISOU 224 O LEU X 303 6734 6886 4041 -659 70 1097 O ATOM 225 CB LEU X 303 9.411 17.255 68.566 1.00 42.84 C ANISOU 225 CB LEU X 303 5826 6191 4257 -594 -58 979 C ATOM 226 CG LEU X 303 10.303 16.634 67.487 1.00 41.35 C ANISOU 226 CG LEU X 303 5641 5808 4260 -471 -276 967 C ATOM 227 CD1 LEU X 303 9.927 17.180 66.127 1.00 39.57 C ANISOU 227 CD1 LEU X 303 5170 5643 4219 -406 -271 795 C ATOM 228 CD2 LEU X 303 11.779 16.879 67.775 1.00 40.56 C ANISOU 228 CD2 LEU X 303 5647 5648 4113 -281 -474 981 C ATOM 229 N ILE X 304 7.717 17.752 71.251 1.00 47.99 N ANISOU 229 N ILE X 304 6662 7168 4402 -953 489 1063 N ATOM 230 CA ILE X 304 7.226 18.745 72.216 1.00 49.19 C ANISOU 230 CA ILE X 304 6807 7539 4344 -983 733 952 C ATOM 231 C ILE X 304 7.736 18.450 73.627 1.00 51.74 C ANISOU 231 C ILE X 304 7540 7864 4252 -1080 742 1111 C ATOM 232 O ILE X 304 7.387 17.433 74.231 1.00 54.68 O ANISOU 232 O ILE X 304 8144 8163 4466 -1302 849 1314 O ATOM 233 CB ILE X 304 5.677 18.899 72.188 1.00 51.04 C ANISOU 233 CB ILE X 304 6758 7924 4708 -1147 1086 839 C ATOM 234 CG1 ILE X 304 5.231 19.543 70.870 1.00 48.56 C ANISOU 234 CG1 ILE X 304 6041 7644 4763 -988 1011 653 C ATOM 235 CG2 ILE X 304 5.189 19.736 73.376 1.00 53.58 C ANISOU 235 CG2 ILE X 304 7128 8454 4775 -1203 1398 724 C ATOM 236 CD1 ILE X 304 3.730 19.526 70.635 1.00 50.49 C ANISOU 236 CD1 ILE X 304 5936 8013 5235 -1127 1267 543 C ATOM 237 N GLY X 305 8.579 19.349 74.127 1.00 50.90 N ANISOU 237 N GLY X 305 7543 7830 3967 -925 610 1021 N ATOM 238 CA GLY X 305 9.217 19.187 75.429 1.00 53.37 C ANISOU 238 CA GLY X 305 8265 8157 3854 -984 526 1152 C ATOM 239 C GLY X 305 10.732 19.202 75.351 1.00 51.82 C ANISOU 239 C GLY X 305 8189 7842 3656 -781 88 1200 C ATOM 240 O GLY X 305 11.402 19.535 76.330 1.00 53.73 O ANISOU 240 O GLY X 305 8690 8143 3579 -761 -53 1212 O ATOM 241 N LEU X 306 11.272 18.842 74.188 1.00 48.78 N ANISOU 241 N LEU X 306 7606 7299 3629 -638 -122 1208 N ATOM 242 CA LEU X 306 12.720 18.793 73.982 1.00 47.54 C ANISOU 242 CA LEU X 306 7479 7023 3558 -440 -509 1228 C ATOM 243 C LEU X 306 13.309 20.189 73.813 1.00 45.52 C ANISOU 243 C LEU X 306 7041 6889 3364 -293 -571 980 C ATOM 244 O LEU X 306 12.627 21.109 73.361 1.00 44.02 O ANISOU 244 O LEU X 306 6635 6805 3282 -287 -347 795 O ATOM 245 CB LEU X 306 13.073 17.933 72.761 1.00 45.69 C ANISOU 245 CB LEU X 306 7089 6579 3690 -348 -649 1281 C ATOM 246 CG LEU X 306 12.591 16.478 72.669 1.00 47.45 C ANISOU 246 CG LEU X 306 7466 6605 3957 -480 -622 1502 C ATOM 247 CD1 LEU X 306 13.021 15.877 71.340 1.00 45.58 C ANISOU 247 CD1 LEU X 306 7042 6176 4099 -356 -751 1458 C ATOM 248 CD2 LEU X 306 13.084 15.616 73.830 1.00 51.12 C ANISOU 248 CD2 LEU X 306 8337 6941 4143 -528 -814 1769 C ATOM 249 N VAL X 307 14.576 20.340 74.190 1.00 45.89 N ANISOU 249 N VAL X 307 7171 6900 3362 -175 -891 979 N ATOM 250 CA VAL X 307 15.305 21.584 73.962 1.00 44.17 C ANISOU 250 CA VAL X 307 6770 6753 3256 -58 -981 747 C ATOM 251 C VAL X 307 16.144 21.454 72.693 1.00 41.51 C ANISOU 251 C VAL X 307 6163 6285 3323 91 -1128 701 C ATOM 252 O VAL X 307 16.902 20.497 72.535 1.00 42.25 O ANISOU 252 O VAL X 307 6281 6239 3533 169 -1359 826 O ATOM 253 CB VAL X 307 16.176 21.981 75.183 1.00 46.85 C ANISOU 253 CB VAL X 307 7329 7166 3303 -50 -1238 719 C ATOM 254 CG1 VAL X 307 17.238 23.004 74.804 1.00 45.67 C ANISOU 254 CG1 VAL X 307 6954 7025 3370 65 -1416 500 C ATOM 255 CG2 VAL X 307 15.298 22.521 76.300 1.00 49.27 C ANISOU 255 CG2 VAL X 307 7877 7644 3199 -202 -1003 660 C ATOM 256 N VAL X 308 15.986 22.417 71.792 1.00 38.81 N ANISOU 256 N VAL X 308 5579 5976 3188 133 -978 520 N ATOM 257 CA VAL X 308 16.701 22.416 70.519 1.00 36.49 C ANISOU 257 CA VAL X 308 5051 5578 3234 241 -1042 458 C ATOM 258 C VAL X 308 17.731 23.542 70.444 1.00 36.16 C ANISOU 258 C VAL X 308 4873 5561 3303 300 -1142 278 C ATOM 259 O VAL X 308 17.497 24.648 70.940 1.00 36.48 O ANISOU 259 O VAL X 308 4943 5690 3228 258 -1063 149 O ATOM 260 CB VAL X 308 15.730 22.481 69.311 1.00 34.30 C ANISOU 260 CB VAL X 308 4630 5285 3115 224 -806 431 C ATOM 261 CG1 VAL X 308 14.908 21.203 69.224 1.00 34.72 C ANISOU 261 CG1 VAL X 308 4772 5278 3140 148 -747 592 C ATOM 262 CG2 VAL X 308 14.815 23.703 69.397 1.00 33.70 C ANISOU 262 CG2 VAL X 308 4507 5323 2975 189 -597 306 C ATOM 263 N LEU X 309 18.875 23.247 69.834 1.00 35.82 N ANISOU 263 N LEU X 309 4672 5428 3508 389 -1299 252 N ATOM 264 CA LEU X 309 19.926 24.239 69.643 1.00 35.73 C ANISOU 264 CA LEU X 309 4484 5425 3665 412 -1372 77 C ATOM 265 C LEU X 309 20.021 24.649 68.180 1.00 33.63 C ANISOU 265 C LEU X 309 4024 5097 3655 425 -1175 -3 C ATOM 266 O LEU X 309 20.218 23.811 67.303 1.00 33.19 O ANISOU 266 O LEU X 309 3888 4962 3759 479 -1148 44 O ATOM 267 CB LEU X 309 21.274 23.705 70.139 1.00 37.99 C ANISOU 267 CB LEU X 309 4695 5676 4061 492 -1701 77 C ATOM 268 CG LEU X 309 22.559 24.419 69.698 1.00 38.55 C ANISOU 268 CG LEU X 309 4482 5733 4430 512 -1778 -109 C ATOM 269 CD1 LEU X 309 22.635 25.850 70.222 1.00 38.75 C ANISOU 269 CD1 LEU X 309 4518 5836 4367 403 -1758 -278 C ATOM 270 CD2 LEU X 309 23.775 23.617 70.135 1.00 41.48 C ANISOU 270 CD2 LEU X 309 4729 6064 4966 629 -2128 -93 C ATOM 271 N THR X 310 19.882 25.946 67.930 1.00 32.80 N ANISOU 271 N THR X 310 3878 5013 3572 371 -1038 -126 N ATOM 272 CA THR X 310 19.990 26.496 66.583 1.00 31.36 C ANISOU 272 CA THR X 310 3572 4762 3579 361 -853 -180 C ATOM 273 C THR X 310 21.453 26.548 66.141 1.00 32.32 C ANISOU 273 C THR X 310 3487 4835 3957 362 -914 -281 C ATOM 274 O THR X 310 22.331 26.919 66.925 1.00 34.07 O ANISOU 274 O THR X 310 3628 5082 4234 339 -1084 -378 O ATOM 275 CB THR X 310 19.351 27.897 66.496 1.00 30.98 C ANISOU 275 CB THR X 310 3580 4705 3483 310 -700 -256 C ATOM 276 OG1 THR X 310 19.835 28.720 67.566 1.00 32.54 O ANISOU 276 OG1 THR X 310 3802 4929 3631 262 -805 -383 O ATOM 277 CG2 THR X 310 17.834 27.800 66.596 1.00 30.06 C ANISOU 277 CG2 THR X 310 3584 4634 3202 332 -589 -177 C ATOM 278 N LYS X 311 21.708 26.169 64.890 1.00 31.56 N ANISOU 278 N LYS X 311 3297 4679 4015 378 -771 -276 N ATOM 279 CA LYS X 311 23.079 26.062 64.369 1.00 32.89 C ANISOU 279 CA LYS X 311 3230 4809 4457 379 -764 -389 C ATOM 280 C LYS X 311 23.689 27.390 63.903 1.00 33.38 C ANISOU 280 C LYS X 311 3191 4842 4650 249 -608 -513 C ATOM 281 O LYS X 311 24.885 27.460 63.618 1.00 35.19 O ANISOU 281 O LYS X 311 3181 5055 5131 212 -582 -635 O ATOM 282 CB LYS X 311 23.173 24.994 63.265 1.00 32.72 C ANISOU 282 CB LYS X 311 3163 4733 4535 445 -644 -366 C ATOM 283 CG LYS X 311 22.034 24.984 62.239 1.00 31.31 C ANISOU 283 CG LYS X 311 3169 4537 4191 413 -444 -283 C ATOM 284 CD LYS X 311 22.415 25.663 60.926 1.00 32.16 C ANISOU 284 CD LYS X 311 3248 4609 4363 326 -185 -352 C ATOM 285 CE LYS X 311 23.325 24.785 60.062 1.00 33.97 C ANISOU 285 CE LYS X 311 3334 4802 4771 361 -65 -452 C ATOM 286 NZ LYS X 311 22.674 23.515 59.630 1.00 33.63 N ANISOU 286 NZ LYS X 311 3406 4724 4645 446 -87 -402 N ATOM 287 N TYR X 312 22.865 28.433 63.853 1.00 32.18 N ANISOU 287 N TYR X 312 3208 4666 4353 180 -500 -485 N ATOM 288 CA TYR X 312 23.274 29.752 63.363 1.00 32.77 C ANISOU 288 CA TYR X 312 3259 4657 4532 43 -337 -566 C ATOM 289 C TYR X 312 23.456 30.765 64.498 1.00 33.84 C ANISOU 289 C TYR X 312 3407 4784 4666 -26 -469 -678 C ATOM 290 O TYR X 312 24.058 31.821 64.308 1.00 35.26 O ANISOU 290 O TYR X 312 3532 4872 4992 -165 -378 -779 O ATOM 291 CB TYR X 312 22.243 30.276 62.357 1.00 31.50 C ANISOU 291 CB TYR X 312 3309 4423 4237 31 -137 -452 C ATOM 292 CG TYR X 312 20.825 30.236 62.884 1.00 29.80 C ANISOU 292 CG TYR X 312 3269 4243 3808 129 -215 -361 C ATOM 293 CD1 TYR X 312 20.311 31.295 63.626 1.00 29.97 C ANISOU 293 CD1 TYR X 312 3387 4224 3776 118 -242 -408 C ATOM 294 CD2 TYR X 312 20.008 29.130 62.660 1.00 28.19 C ANISOU 294 CD2 TYR X 312 3117 4107 3484 222 -246 -254 C ATOM 295 CE1 TYR X 312 19.024 31.259 64.121 1.00 29.02 C ANISOU 295 CE1 TYR X 312 3381 4149 3495 210 -270 -357 C ATOM 296 CE2 TYR X 312 18.714 29.085 63.153 1.00 27.15 C ANISOU 296 CE2 TYR X 312 3095 4022 3198 286 -288 -189 C ATOM 297 CZ TYR X 312 18.229 30.152 63.885 1.00 27.66 C ANISOU 297 CZ TYR X 312 3224 4065 3220 286 -287 -244 C ATOM 298 OH TYR X 312 16.946 30.120 64.375 1.00 27.24 O ANISOU 298 OH TYR X 312 3236 4068 3043 352 -285 -211 O ATOM 299 N ASN X 313 22.909 30.442 65.668 1.00 33.46 N ANISOU 299 N ASN X 313 3457 4819 4434 49 -666 -664 N ATOM 300 CA ASN X 313 23.029 31.276 66.864 1.00 34.73 C ANISOU 300 CA ASN X 313 3672 4993 4529 -10 -811 -796 C ATOM 301 C ASN X 313 23.057 30.360 68.085 1.00 35.30 C ANISOU 301 C ASN X 313 3783 5198 4428 67 -1085 -775 C ATOM 302 O ASN X 313 22.214 29.471 68.212 1.00 33.94 O ANISOU 302 O ASN X 313 3737 5082 4074 160 -1084 -629 O ATOM 303 CB ASN X 313 21.854 32.257 66.950 1.00 34.10 C ANISOU 303 CB ASN X 313 3811 4843 4300 -11 -668 -795 C ATOM 304 CG ASN X 313 22.187 33.519 67.738 1.00 36.23 C ANISOU 304 CG ASN X 313 4128 5040 4598 -118 -718 -991 C ATOM 305 OD1 ASN X 313 23.004 33.503 68.659 1.00 38.40 O ANISOU 305 OD1 ASN X 313 4331 5381 4878 -179 -933 -1125 O ATOM 306 ND2 ASN X 313 21.542 34.622 67.376 1.00 36.37 N ANISOU 306 ND2 ASN X 313 4275 4902 4639 -135 -545 -1016 N ATOM 307 N ASN X 314 24.020 30.579 68.979 1.00 37.57 N ANISOU 307 N ASN X 314 3978 5528 4768 12 -1331 -914 N ATOM 308 CA ASN X 314 24.222 29.689 70.131 1.00 38.95 C ANISOU 308 CA ASN X 314 4215 5818 4764 86 -1651 -872 C ATOM 309 C ASN X 314 23.161 29.820 71.236 1.00 38.98 C ANISOU 309 C ASN X 314 4542 5899 4368 86 -1676 -845 C ATOM 310 O ASN X 314 23.483 29.894 72.425 1.00 41.40 O ANISOU 310 O ASN X 314 4959 6288 4481 54 -1932 -922 O ATOM 311 CB ASN X 314 25.646 29.828 70.694 1.00 42.12 C ANISOU 311 CB ASN X 314 4392 6252 5359 39 -1966 -1032 C ATOM 312 CG ASN X 314 25.920 31.204 71.277 1.00 44.31 C ANISOU 312 CG ASN X 314 4698 6510 5627 -124 -2006 -1260 C ATOM 313 OD1 ASN X 314 25.613 32.228 70.663 1.00 44.03 O ANISOU 313 OD1 ASN X 314 4682 6361 5684 -224 -1731 -1335 O ATOM 314 ND2 ASN X 314 26.505 31.232 72.469 1.00 47.41 N ANISOU 314 ND2 ASN X 314 5117 6994 5902 -153 -2374 -1373 N ATOM 315 N LYS X 315 21.896 29.835 70.827 1.00 36.69 N ANISOU 315 N LYS X 315 4395 5592 3952 117 -1406 -746 N ATOM 316 CA LYS X 315 20.774 29.918 71.755 1.00 36.95 C ANISOU 316 CA LYS X 315 4692 5706 3641 114 -1339 -733 C ATOM 317 C LYS X 315 19.980 28.621 71.734 1.00 35.82 C ANISOU 317 C LYS X 315 4647 5617 3346 181 -1296 -507 C ATOM 318 O LYS X 315 19.778 28.027 70.675 1.00 33.84 O ANISOU 318 O LYS X 315 4282 5307 3267 235 -1188 -388 O ATOM 319 CB LYS X 315 19.860 31.094 71.398 1.00 36.09 C ANISOU 319 CB LYS X 315 4634 5524 3555 95 -1055 -837 C ATOM 320 CG LYS X 315 20.573 32.434 71.300 1.00 37.44 C ANISOU 320 CG LYS X 315 4737 5577 3910 9 -1061 -1050 C ATOM 321 CD LYS X 315 19.593 33.600 71.310 1.00 37.77 C ANISOU 321 CD LYS X 315 4901 5523 3926 18 -828 -1168 C ATOM 322 CE LYS X 315 20.295 34.917 70.999 1.00 39.04 C ANISOU 322 CE LYS X 315 5010 5498 4325 -79 -810 -1348 C ATOM 323 NZ LYS X 315 21.440 35.196 71.915 1.00 41.46 N ANISOU 323 NZ LYS X 315 5298 5841 4613 -208 -1064 -1542 N ATOM 324 N THR X 316 19.538 28.186 72.909 1.00 37.55 N ANISOU 324 N THR X 316 5099 5940 3226 156 -1373 -455 N ATOM 325 CA THR X 316 18.679 27.011 73.024 1.00 37.24 C ANISOU 325 CA THR X 316 5192 5937 3020 173 -1297 -239 C ATOM 326 C THR X 316 17.229 27.404 73.271 1.00 37.05 C ANISOU 326 C THR X 316 5284 5978 2813 126 -980 -267 C ATOM 327 O THR X 316 16.948 28.400 73.942 1.00 38.40 O ANISOU 327 O THR X 316 5550 6202 2838 84 -888 -449 O ATOM 328 CB THR X 316 19.138 26.061 74.144 1.00 39.94 C ANISOU 328 CB THR X 316 5747 6332 3094 161 -1583 -104 C ATOM 329 OG1 THR X 316 19.496 26.820 75.305 1.00 42.80 O ANISOU 329 OG1 THR X 316 6278 6789 3193 94 -1730 -259 O ATOM 330 CG2 THR X 316 20.325 25.238 73.689 1.00 40.19 C ANISOU 330 CG2 THR X 316 5613 6270 3385 261 -1876 -14 C ATOM 331 N TYR X 317 16.315 26.613 72.719 1.00 35.82 N ANISOU 331 N TYR X 317 5100 5813 2696 133 -812 -113 N ATOM 332 CA TYR X 317 14.887 26.859 72.858 1.00 36.12 C ANISOU 332 CA TYR X 317 5168 5921 2633 94 -505 -141 C ATOM 333 C TYR X 317 14.175 25.571 73.223 1.00 37.18 C ANISOU 333 C TYR X 317 5429 6101 2597 14 -436 63 C ATOM 334 O TYR X 317 14.513 24.502 72.715 1.00 36.48 O ANISOU 334 O TYR X 317 5318 5927 2615 28 -568 236 O ATOM 335 CB TYR X 317 14.297 27.389 71.550 1.00 33.77 C ANISOU 335 CB TYR X 317 4638 5551 2642 169 -343 -186 C ATOM 336 CG TYR X 317 14.974 28.617 70.988 1.00 33.06 C ANISOU 336 CG TYR X 317 4442 5364 2752 230 -386 -343 C ATOM 337 CD1 TYR X 317 14.489 29.893 71.270 1.00 34.01 C ANISOU 337 CD1 TYR X 317 4573 5471 2878 254 -241 -532 C ATOM 338 CD2 TYR X 317 16.093 28.503 70.159 1.00 31.80 C ANISOU 338 CD2 TYR X 317 4175 5109 2799 256 -546 -310 C ATOM 339 CE1 TYR X 317 15.106 31.026 70.749 1.00 33.88 C ANISOU 339 CE1 TYR X 317 4494 5321 3058 287 -275 -658 C ATOM 340 CE2 TYR X 317 16.717 29.627 69.637 1.00 31.74 C ANISOU 340 CE2 TYR X 317 4084 5000 2976 268 -548 -439 C ATOM 341 CZ TYR X 317 16.219 30.884 69.934 1.00 32.78 C ANISOU 341 CZ TYR X 317 4260 5093 3101 276 -423 -599 C ATOM 342 OH TYR X 317 16.836 31.998 69.415 1.00 33.32 O ANISOU 342 OH TYR X 317 4279 5018 3363 266 -421 -709 O ATOM 343 N ARG X 318 13.184 25.677 74.099 1.00 39.43 N ANISOU 343 N ARG X 318 5847 6503 2629 -81 -203 29 N ATOM 344 CA ARG X 318 12.320 24.550 74.408 1.00 40.90 C ANISOU 344 CA ARG X 318 6138 6728 2673 -204 -54 215 C ATOM 345 C ARG X 318 11.169 24.537 73.404 1.00 39.45 C ANISOU 345 C ARG X 318 5680 6537 2770 -194 182 193 C ATOM 346 O ARG X 318 10.353 25.460 73.385 1.00 39.84 O ANISOU 346 O ARG X 318 5589 6660 2886 -163 409 14 O ATOM 347 CB ARG X 318 11.787 24.667 75.838 1.00 44.49 C ANISOU 347 CB ARG X 318 6867 7330 2704 -345 133 179 C ATOM 348 CG ARG X 318 11.104 23.414 76.365 1.00 46.92 C ANISOU 348 CG ARG X 318 7369 7662 2796 -524 272 412 C ATOM 349 CD ARG X 318 10.286 23.723 77.606 1.00 51.20 C ANISOU 349 CD ARG X 318 8130 8380 2944 -685 602 325 C ATOM 350 NE ARG X 318 9.765 22.515 78.242 1.00 54.60 N ANISOU 350 NE ARG X 318 8819 8820 3104 -901 739 580 N ATOM 351 CZ ARG X 318 8.608 21.931 77.933 1.00 55.37 C ANISOU 351 CZ ARG X 318 8766 8933 3339 -1041 1060 646 C ATOM 352 NH1 ARG X 318 8.231 20.835 78.580 1.00 58.61 N ANISOU 352 NH1 ARG X 318 9458 9324 3486 -1272 1184 893 N ATOM 353 NH2 ARG X 318 7.825 22.434 76.984 1.00 53.00 N ANISOU 353 NH2 ARG X 318 8038 8655 3443 -961 1239 473 N ATOM 354 N VAL X 319 11.116 23.510 72.558 1.00 38.28 N ANISOU 354 N VAL X 319 5449 6291 2804 -206 104 357 N ATOM 355 CA VAL X 319 9.992 23.360 71.628 1.00 37.64 C ANISOU 355 CA VAL X 319 5119 6213 2967 -221 278 342 C ATOM 356 C VAL X 319 8.745 22.866 72.370 1.00 40.47 C ANISOU 356 C VAL X 319 5507 6682 3187 -405 572 381 C ATOM 357 O VAL X 319 8.726 21.759 72.911 1.00 42.21 O ANISOU 357 O VAL X 319 5929 6868 3238 -561 578 568 O ATOM 358 CB VAL X 319 10.336 22.485 70.369 1.00 35.58 C ANISOU 358 CB VAL X 319 4761 5806 2950 -183 99 456 C ATOM 359 CG1 VAL X 319 11.041 21.196 70.745 1.00 36.56 C ANISOU 359 CG1 VAL X 319 5108 5815 2968 -249 -67 654 C ATOM 360 CG2 VAL X 319 9.084 22.196 69.542 1.00 35.52 C ANISOU 360 CG2 VAL X 319 4530 5819 3145 -240 244 442 C ATOM 361 N ASP X 320 7.718 23.711 72.409 1.00 41.48 N ANISOU 361 N ASP X 320 5430 6928 3401 -387 826 201 N ATOM 362 CA ASP X 320 6.478 23.386 73.115 1.00 44.81 C ANISOU 362 CA ASP X 320 5809 7482 3731 -568 1173 185 C ATOM 363 C ASP X 320 5.251 23.303 72.196 1.00 44.86 C ANISOU 363 C ASP X 320 5427 7521 4095 -574 1304 121 C ATOM 364 O ASP X 320 4.119 23.165 72.671 1.00 47.69 O ANISOU 364 O ASP X 320 5644 8005 4469 -716 1623 58 O ATOM 365 CB ASP X 320 6.241 24.349 74.293 1.00 47.44 C ANISOU 365 CB ASP X 320 6248 7960 3816 -572 1422 -6 C ATOM 366 CG ASP X 320 6.457 25.808 73.922 1.00 46.28 C ANISOU 366 CG ASP X 320 5946 7794 3841 -337 1365 -246 C ATOM 367 OD1 ASP X 320 5.790 26.301 72.987 1.00 45.55 O ANISOU 367 OD1 ASP X 320 5525 7678 4101 -207 1390 -342 O ATOM 368 OD2 ASP X 320 7.289 26.467 74.583 1.00 46.72 O ANISOU 368 OD2 ASP X 320 6225 7844 3679 -287 1278 -335 O ATOM 369 N ASP X 321 5.488 23.380 70.886 1.00 42.17 N ANISOU 369 N ASP X 321 4914 7074 4033 -432 1056 129 N ATOM 370 CA ASP X 321 4.442 23.181 69.878 1.00 42.37 C ANISOU 370 CA ASP X 321 4598 7116 4384 -436 1071 90 C ATOM 371 C ASP X 321 5.031 23.108 68.467 1.00 39.36 C ANISOU 371 C ASP X 321 4174 6598 4182 -301 746 141 C ATOM 372 O ASP X 321 6.124 23.623 68.215 1.00 37.21 O ANISOU 372 O ASP X 321 4048 6239 3848 -160 569 146 O ATOM 373 CB ASP X 321 3.378 24.287 69.956 1.00 44.24 C ANISOU 373 CB ASP X 321 4520 7479 4809 -322 1274 -131 C ATOM 374 CG ASP X 321 1.991 23.807 69.540 1.00 46.73 C ANISOU 374 CG ASP X 321 4467 7884 5405 -431 1404 -176 C ATOM 375 OD1 ASP X 321 1.877 22.762 68.859 1.00 46.38 O ANISOU 375 OD1 ASP X 321 4392 7779 5452 -564 1267 -50 O ATOM 376 OD2 ASP X 321 1.005 24.486 69.899 1.00 49.70 O ANISOU 376 OD2 ASP X 321 4562 8387 5934 -382 1645 -362 O ATOM 377 N ILE X 322 4.302 22.456 67.562 1.00 39.66 N ANISOU 377 N ILE X 322 4012 6623 4432 -369 681 163 N ATOM 378 CA ILE X 322 4.682 22.362 66.150 1.00 37.62 C ANISOU 378 CA ILE X 322 3722 6258 4314 -264 400 186 C ATOM 379 C ILE X 322 3.554 22.886 65.256 1.00 38.66 C ANISOU 379 C ILE X 322 3517 6461 4711 -180 342 75 C ATOM 380 O ILE X 322 2.455 22.325 65.227 1.00 40.93 O ANISOU 380 O ILE X 322 3569 6826 5153 -322 422 42 O ATOM 381 CB ILE X 322 5.057 20.911 65.742 1.00 37.29 C ANISOU 381 CB ILE X 322 3827 6091 4248 -423 285 318 C ATOM 382 CG1 ILE X 322 6.234 20.398 66.582 1.00 36.83 C ANISOU 382 CG1 ILE X 322 4096 5936 3962 -457 276 443 C ATOM 383 CG2 ILE X 322 5.384 20.840 64.246 1.00 35.63 C ANISOU 383 CG2 ILE X 322 3596 5790 4151 -325 31 300 C ATOM 384 CD1 ILE X 322 6.450 18.895 66.514 1.00 37.68 C ANISOU 384 CD1 ILE X 322 4364 5890 4060 -622 214 582 C ATOM 385 N ASP X 323 3.840 23.965 64.532 1.00 37.44 N ANISOU 385 N ASP X 323 3340 6267 4619 43 187 24 N ATOM 386 CA ASP X 323 2.859 24.614 63.667 1.00 38.78 C ANISOU 386 CA ASP X 323 3226 6478 5028 178 63 -59 C ATOM 387 C ASP X 323 2.867 23.989 62.269 1.00 38.19 C ANISOU 387 C ASP X 323 3167 6344 4997 151 -218 0 C ATOM 388 O ASP X 323 3.689 24.342 61.419 1.00 36.48 O ANISOU 388 O ASP X 323 3148 6025 4686 260 -395 51 O ATOM 389 CB ASP X 323 3.133 26.124 63.598 1.00 38.44 C ANISOU 389 CB ASP X 323 3204 6380 5018 433 27 -121 C ATOM 390 CG ASP X 323 1.947 26.923 63.074 1.00 40.95 C ANISOU 390 CG ASP X 323 3200 6739 5619 610 -64 -217 C ATOM 391 OD1 ASP X 323 1.233 26.446 62.166 1.00 42.24 O ANISOU 391 OD1 ASP X 323 3184 6940 5925 586 -262 -201 O ATOM 392 OD2 ASP X 323 1.739 28.049 63.569 1.00 42.25 O ANISOU 392 OD2 ASP X 323 3291 6884 5877 787 38 -321 O ATOM 393 N TRP X 324 1.937 23.062 62.043 1.00 40.03 N ANISOU 393 N TRP X 324 3200 6643 5365 -16 -241 -23 N ATOM 394 CA TRP X 324 1.820 22.354 60.764 1.00 40.10 C ANISOU 394 CA TRP X 324 3225 6606 5403 -79 -512 -6 C ATOM 395 C TRP X 324 1.147 23.202 59.681 1.00 41.50 C ANISOU 395 C TRP X 324 3225 6820 5720 109 -789 -56 C ATOM 396 O TRP X 324 1.071 22.791 58.521 1.00 41.91 O ANISOU 396 O TRP X 324 3332 6845 5745 81 -1056 -49 O ATOM 397 CB TRP X 324 1.069 21.031 60.950 1.00 42.04 C ANISOU 397 CB TRP X 324 3327 6886 5758 -360 -449 -27 C ATOM 398 CG TRP X 324 1.754 20.078 61.886 1.00 41.24 C ANISOU 398 CG TRP X 324 3469 6699 5502 -548 -234 66 C ATOM 399 CD1 TRP X 324 1.511 19.925 63.221 1.00 42.42 C ANISOU 399 CD1 TRP X 324 3593 6904 5621 -672 67 92 C ATOM 400 CD2 TRP X 324 2.799 19.154 61.559 1.00 39.67 C ANISOU 400 CD2 TRP X 324 3594 6328 5148 -618 -316 150 C ATOM 401 NE1 TRP X 324 2.338 18.961 63.746 1.00 41.62 N ANISOU 401 NE1 TRP X 324 3804 6666 5341 -813 137 220 N ATOM 402 CE2 TRP X 324 3.139 18.471 62.748 1.00 39.88 C ANISOU 402 CE2 TRP X 324 3778 6297 5076 -766 -98 249 C ATOM 403 CE3 TRP X 324 3.482 18.836 60.376 1.00 38.45 C ANISOU 403 CE3 TRP X 324 3623 6060 4926 -564 -541 141 C ATOM 404 CZ2 TRP X 324 4.133 17.488 62.790 1.00 38.98 C ANISOU 404 CZ2 TRP X 324 3970 5993 4846 -830 -139 348 C ATOM 405 CZ3 TRP X 324 4.470 17.857 60.418 1.00 37.38 C ANISOU 405 CZ3 TRP X 324 3766 5750 4685 -635 -531 203 C ATOM 406 CH2 TRP X 324 4.785 17.195 61.619 1.00 37.79 C ANISOU 406 CH2 TRP X 324 3942 5726 4689 -751 -351 309 C ATOM 407 N ASP X 325 0.667 24.383 60.068 1.00 42.62 N ANISOU 407 N ASP X 325 3178 7011 6001 309 -737 -109 N ATOM 408 CA ASP X 325 0.023 25.314 59.141 1.00 44.55 C ANISOU 408 CA ASP X 325 3266 7258 6402 538 -1025 -133 C ATOM 409 C ASP X 325 0.995 26.382 58.632 1.00 42.77 C ANISOU 409 C ASP X 325 3363 6883 6003 747 -1132 -37 C ATOM 410 O ASP X 325 0.613 27.264 57.859 1.00 44.40 O ANISOU 410 O ASP X 325 3533 7041 6294 956 -1382 -10 O ATOM 411 CB ASP X 325 -1.195 25.972 59.800 1.00 47.75 C ANISOU 411 CB ASP X 325 3230 7775 7137 658 -920 -268 C ATOM 412 CG ASP X 325 -2.160 24.961 60.396 1.00 50.25 C ANISOU 412 CG ASP X 325 3201 8246 7643 409 -739 -371 C ATOM 413 OD1 ASP X 325 -2.264 23.833 59.862 1.00 50.48 O ANISOU 413 OD1 ASP X 325 3251 8289 7637 185 -864 -346 O ATOM 414 OD2 ASP X 325 -2.818 25.299 61.404 1.00 52.60 O ANISOU 414 OD2 ASP X 325 3215 8642 8125 423 -449 -491 O ATOM 415 N GLN X 326 2.248 26.296 59.070 1.00 39.87 N ANISOU 415 N GLN X 326 3308 6432 5408 684 -952 21 N ATOM 416 CA GLN X 326 3.294 27.202 58.605 1.00 38.38 C ANISOU 416 CA GLN X 326 3426 6095 5059 818 -1008 106 C ATOM 417 C GLN X 326 4.485 26.445 58.027 1.00 36.09 C ANISOU 417 C GLN X 326 3451 5740 4520 679 -1019 181 C ATOM 418 O GLN X 326 4.764 25.311 58.421 1.00 35.13 O ANISOU 418 O GLN X 326 3349 5653 4343 502 -912 164 O ATOM 419 CB GLN X 326 3.758 28.128 59.732 1.00 37.74 C ANISOU 419 CB GLN X 326 3380 5962 4996 908 -771 62 C ATOM 420 CG GLN X 326 2.808 29.279 60.031 1.00 40.51 C ANISOU 420 CG GLN X 326 3496 6301 5592 1129 -778 -21 C ATOM 421 CD GLN X 326 3.394 30.271 61.016 1.00 40.42 C ANISOU 421 CD GLN X 326 3591 6199 5567 1216 -562 -89 C ATOM 422 OE1 GLN X 326 4.422 30.897 60.753 1.00 39.32 O ANISOU 422 OE1 GLN X 326 3729 5906 5303 1250 -587 -22 O ATOM 423 NE2 GLN X 326 2.738 30.424 62.158 1.00 42.24 N ANISOU 423 NE2 GLN X 326 3601 6523 5923 1232 -332 -241 N ATOM 424 N ASN X 327 5.175 27.089 57.088 1.00 35.72 N ANISOU 424 N ASN X 327 3654 5581 4334 762 -1134 262 N ATOM 425 CA ASN X 327 6.375 26.536 56.460 1.00 34.08 C ANISOU 425 CA ASN X 327 3733 5309 3906 651 -1101 305 C ATOM 426 C ASN X 327 7.437 27.631 56.250 1.00 33.27 C ANISOU 426 C ASN X 327 3863 5071 3705 729 -1026 371 C ATOM 427 O ASN X 327 7.188 28.790 56.585 1.00 33.95 O ANISOU 427 O ASN X 327 3912 5092 3893 868 -1025 389 O ATOM 428 CB ASN X 327 6.011 25.818 55.152 1.00 35.47 C ANISOU 428 CB ASN X 327 3995 5513 3967 583 -1324 313 C ATOM 429 CG ASN X 327 5.324 26.727 54.153 1.00 38.12 C ANISOU 429 CG ASN X 327 4376 5826 4278 727 -1596 387 C ATOM 430 OD1 ASN X 327 5.910 27.695 53.667 1.00 38.55 O ANISOU 430 OD1 ASN X 327 4664 5767 4214 817 -1604 486 O ATOM 431 ND2 ASN X 327 4.075 26.409 53.830 1.00 40.58 N ANISOU 431 ND2 ASN X 327 4468 6237 4712 742 -1836 346 N ATOM 432 N PRO X 328 8.624 27.273 55.710 1.00 32.15 N ANISOU 432 N PRO X 328 3948 4873 3393 633 -943 390 N ATOM 433 CA PRO X 328 9.701 28.260 55.541 1.00 31.77 C ANISOU 433 CA PRO X 328 4093 4698 3278 656 -828 441 C ATOM 434 C PRO X 328 9.378 29.461 54.640 1.00 33.78 C ANISOU 434 C PRO X 328 4517 4842 3476 762 -963 559 C ATOM 435 O PRO X 328 10.128 30.441 54.646 1.00 34.05 O ANISOU 435 O PRO X 328 4697 4739 3499 773 -855 610 O ATOM 436 CB PRO X 328 10.835 27.434 54.929 1.00 31.05 C ANISOU 436 CB PRO X 328 4160 4597 3037 522 -716 412 C ATOM 437 CG PRO X 328 10.584 26.064 55.395 1.00 30.23 C ANISOU 437 CG PRO X 328 3917 4584 2985 451 -721 331 C ATOM 438 CD PRO X 328 9.099 25.912 55.395 1.00 31.46 C ANISOU 438 CD PRO X 328 3917 4820 3213 491 -905 337 C ATOM 439 N LYS X 329 8.288 29.386 53.877 1.00 35.58 N ANISOU 439 N LYS X 329 4732 5113 3675 832 -1215 609 N ATOM 440 CA LYS X 329 7.849 30.519 53.057 1.00 38.00 C ANISOU 440 CA LYS X 329 5208 5295 3933 969 -1412 752 C ATOM 441 C LYS X 329 6.864 31.426 53.796 1.00 39.13 C ANISOU 441 C LYS X 329 5118 5390 4357 1178 -1511 742 C ATOM 442 O LYS X 329 6.506 32.496 53.297 1.00 41.57 O ANISOU 442 O LYS X 329 5554 5547 4694 1335 -1680 864 O ATOM 443 CB LYS X 329 7.259 30.052 51.722 1.00 40.24 C ANISOU 443 CB LYS X 329 5644 5638 4007 952 -1693 820 C ATOM 444 CG LYS X 329 8.289 29.488 50.755 1.00 40.24 C ANISOU 444 CG LYS X 329 5973 5636 3679 770 -1574 835 C ATOM 445 CD LYS X 329 7.779 29.474 49.321 1.00 43.71 C ANISOU 445 CD LYS X 329 6692 6088 3828 770 -1868 939 C ATOM 446 CE LYS X 329 8.085 30.781 48.605 1.00 46.42 C ANISOU 446 CE LYS X 329 7395 6245 3995 835 -1915 1157 C ATOM 447 NZ LYS X 329 7.729 30.716 47.161 1.00 50.24 N ANISOU 447 NZ LYS X 329 8241 6745 4102 807 -2195 1277 N ATOM 448 N SER X 330 6.433 30.997 54.983 1.00 37.78 N ANISOU 448 N SER X 330 4626 5334 4391 1181 -1394 597 N ATOM 449 CA SER X 330 5.586 31.821 55.846 1.00 38.96 C ANISOU 449 CA SER X 330 4530 5451 4820 1368 -1396 530 C ATOM 450 C SER X 330 6.353 33.039 56.340 1.00 38.65 C ANISOU 450 C SER X 330 4652 5209 4823 1432 -1236 542 C ATOM 451 O SER X 330 7.583 33.019 56.429 1.00 36.81 O ANISOU 451 O SER X 330 4617 4920 4446 1286 -1059 554 O ATOM 452 CB SER X 330 5.048 31.019 57.034 1.00 37.98 C ANISOU 452 CB SER X 330 4074 5512 4846 1303 -1235 365 C ATOM 453 OG SER X 330 4.038 30.115 56.624 1.00 39.37 O ANISOU 453 OG SER X 330 4035 5844 5081 1266 -1407 338 O ATOM 454 N THR X 331 5.615 34.097 56.658 1.00 40.83 N ANISOU 454 N THR X 331 4820 5363 5330 1653 -1305 517 N ATOM 455 CA THR X 331 6.212 35.376 57.028 1.00 41.34 C ANISOU 455 CA THR X 331 5059 5178 5467 1730 -1192 520 C ATOM 456 C THR X 331 5.939 35.749 58.488 1.00 41.17 C ANISOU 456 C THR X 331 4809 5176 5657 1801 -980 301 C ATOM 457 O THR X 331 4.992 35.250 59.099 1.00 41.74 O ANISOU 457 O THR X 331 4563 5429 5866 1855 -949 169 O ATOM 458 CB THR X 331 5.749 36.511 56.067 1.00 44.75 C ANISOU 458 CB THR X 331 5672 5352 5975 1946 -1454 693 C ATOM 459 OG1 THR X 331 6.306 37.762 56.486 1.00 45.94 O ANISOU 459 OG1 THR X 331 6001 5218 6234 2006 -1329 684 O ATOM 460 CG2 THR X 331 4.225 36.622 56.027 1.00 47.60 C ANISOU 460 CG2 THR X 331 5715 5766 6603 2209 -1700 649 C ATOM 461 N PHE X 332 6.785 36.614 59.041 1.00 40.78 N ANISOU 461 N PHE X 332 4930 4942 5620 1773 -818 247 N ATOM 462 CA PHE X 332 6.575 37.144 60.388 1.00 41.25 C ANISOU 462 CA PHE X 332 4844 4985 5843 1845 -623 17 C ATOM 463 C PHE X 332 6.908 38.633 60.476 1.00 43.27 C ANISOU 463 C PHE X 332 5299 4897 6245 1964 -604 -7 C ATOM 464 O PHE X 332 7.493 39.205 59.553 1.00 43.89 O ANISOU 464 O PHE X 332 5657 4749 6270 1939 -709 178 O ATOM 465 CB PHE X 332 7.351 36.327 61.434 1.00 38.56 C ANISOU 465 CB PHE X 332 4476 4844 5331 1615 -401 -110 C ATOM 466 CG PHE X 332 8.842 36.520 61.388 1.00 36.94 C ANISOU 466 CG PHE X 332 4526 4532 4977 1428 -334 -70 C ATOM 467 CD1 PHE X 332 9.466 37.433 62.236 1.00 37.44 C ANISOU 467 CD1 PHE X 332 4686 4443 5093 1403 -207 -220 C ATOM 468 CD2 PHE X 332 9.628 35.776 60.512 1.00 35.21 C ANISOU 468 CD2 PHE X 332 4426 4367 4582 1267 -387 85 C ATOM 469 CE1 PHE X 332 10.845 37.612 62.203 1.00 36.24 C ANISOU 469 CE1 PHE X 332 4715 4204 4851 1211 -156 -204 C ATOM 470 CE2 PHE X 332 11.011 35.947 60.472 1.00 34.07 C ANISOU 470 CE2 PHE X 332 4452 4139 4352 1092 -299 95 C ATOM 471 CZ PHE X 332 11.618 36.866 61.321 1.00 34.75 C ANISOU 471 CZ PHE X 332 4599 4082 4520 1058 -195 -44 C ATOM 472 N LYS X 333 6.522 39.250 61.590 1.00 44.64 N ANISOU 472 N LYS X 333 5346 5020 6593 2078 -451 -244 N ATOM 473 CA LYS X 333 6.758 40.668 61.823 1.00 47.02 C ANISOU 473 CA LYS X 333 5824 4967 7072 2198 -416 -323 C ATOM 474 C LYS X 333 8.003 40.860 62.688 1.00 45.56 C ANISOU 474 C LYS X 333 5807 4752 6750 1961 -216 -467 C ATOM 475 O LYS X 333 8.077 40.354 63.810 1.00 44.49 O ANISOU 475 O LYS X 333 5547 4838 6516 1864 -46 -671 O ATOM 476 CB LYS X 333 5.532 41.297 62.490 1.00 50.30 C ANISOU 476 CB LYS X 333 5995 5320 7795 2493 -368 -543 C ATOM 477 CG LYS X 333 5.461 42.812 62.408 1.00 53.84 C ANISOU 477 CG LYS X 333 6617 5326 8513 2713 -416 -587 C ATOM 478 CD LYS X 333 4.238 43.326 63.148 1.00 57.38 C ANISOU 478 CD LYS X 333 6768 5739 9292 3023 -328 -860 C ATOM 479 CE LYS X 333 4.069 44.822 62.974 1.00 61.68 C ANISOU 479 CE LYS X 333 7483 5793 10159 3293 -413 -896 C ATOM 480 NZ LYS X 333 2.863 45.321 63.691 1.00 65.75 N ANISOU 480 NZ LYS X 333 7671 6266 11043 3629 -306 -1201 N ATOM 481 N LYS X 334 8.981 41.585 62.149 1.00 45.96 N ANISOU 481 N LYS X 334 6147 4527 6788 1852 -247 -353 N ATOM 482 CA LYS X 334 10.232 41.863 62.854 1.00 45.24 C ANISOU 482 CA LYS X 334 6196 4380 6614 1613 -101 -491 C ATOM 483 C LYS X 334 10.031 42.900 63.954 1.00 47.83 C ANISOU 483 C LYS X 334 6541 4513 7116 1712 16 -789 C ATOM 484 O LYS X 334 9.006 43.588 63.991 1.00 50.55 O ANISOU 484 O LYS X 334 6828 4686 7690 1988 -6 -860 O ATOM 485 CB LYS X 334 11.307 42.346 61.875 1.00 45.51 C ANISOU 485 CB LYS X 334 6505 4170 6617 1436 -139 -286 C ATOM 486 CG LYS X 334 11.963 41.249 61.047 1.00 43.08 C ANISOU 486 CG LYS X 334 6202 4087 6079 1242 -164 -85 C ATOM 487 CD LYS X 334 12.728 41.831 59.857 1.00 45.06 C ANISOU 487 CD LYS X 334 6741 4075 6304 1107 -174 146 C ATOM 488 CE LYS X 334 14.124 42.317 60.237 1.00 45.89 C ANISOU 488 CE LYS X 334 6943 4051 6443 829 -15 40 C ATOM 489 NZ LYS X 334 15.108 41.200 60.355 1.00 43.63 N ANISOU 489 NZ LYS X 334 6508 4069 5998 602 64 0 N ATOM 490 N ALA X 335 11.020 43.006 64.841 1.00 47.34 N ANISOU 490 N ALA X 335 6553 4476 6956 1494 128 -980 N ATOM 491 CA ALA X 335 11.002 43.969 65.944 1.00 49.99 C ANISOU 491 CA ALA X 335 6954 4634 7405 1535 245 -1306 C ATOM 492 C ALA X 335 10.868 45.411 65.452 1.00 53.49 C ANISOU 492 C ALA X 335 7600 4576 8146 1676 207 -1295 C ATOM 493 O ALA X 335 10.252 46.243 66.122 1.00 56.54 O ANISOU 493 O ALA X 335 7992 4768 8720 1865 286 -1548 O ATOM 494 CB ALA X 335 12.245 43.810 66.807 1.00 49.08 C ANISOU 494 CB ALA X 335 6911 4624 7110 1237 298 -1480 C ATOM 495 N ASP X 336 11.443 45.691 64.282 1.00 53.42 N ANISOU 495 N ASP X 336 7777 4347 8173 1582 103 -1004 N ATOM 496 CA ASP X 336 11.341 47.010 63.653 1.00 57.08 C ANISOU 496 CA ASP X 336 8493 4294 8899 1698 43 -908 C ATOM 497 C ASP X 336 10.011 47.219 62.923 1.00 58.96 C ANISOU 497 C ASP X 336 8680 4408 9311 2074 -113 -735 C ATOM 498 O ASP X 336 9.685 48.339 62.534 1.00 62.73 O ANISOU 498 O ASP X 336 9352 4434 10046 2259 -194 -675 O ATOM 499 CB ASP X 336 12.521 47.266 62.707 1.00 57.01 C ANISOU 499 CB ASP X 336 8742 4085 8832 1409 28 -654 C ATOM 500 CG ASP X 336 12.634 46.221 61.615 1.00 54.51 C ANISOU 500 CG ASP X 336 8388 4036 8285 1332 -49 -328 C ATOM 501 OD1 ASP X 336 13.060 45.086 61.918 1.00 51.48 O ANISOU 501 OD1 ASP X 336 7810 4058 7691 1177 -1 -377 O ATOM 502 OD2 ASP X 336 12.309 46.541 60.451 1.00 56.13 O ANISOU 502 OD2 ASP X 336 8786 4030 8509 1428 -170 -24 O ATOM 503 N GLY X 337 9.254 46.140 62.733 1.00 56.75 N ANISOU 503 N GLY X 337 8137 4513 8913 2185 -180 -656 N ATOM 504 CA GLY X 337 7.902 46.232 62.180 1.00 58.76 C ANISOU 504 CA GLY X 337 8247 4717 9359 2550 -356 -548 C ATOM 505 C GLY X 337 7.761 45.895 60.707 1.00 58.44 C ANISOU 505 C GLY X 337 8323 4666 9216 2575 -607 -143 C ATOM 506 O GLY X 337 6.674 46.029 60.140 1.00 60.72 O ANISOU 506 O GLY X 337 8510 4889 9670 2882 -826 -28 O ATOM 507 N SER X 338 8.856 45.465 60.083 1.00 56.04 N ANISOU 507 N SER X 338 8226 4428 8638 2257 -581 56 N ATOM 508 CA SER X 338 8.826 45.035 58.686 1.00 55.77 C ANISOU 508 CA SER X 338 8345 4428 8418 2229 -779 418 C ATOM 509 C SER X 338 8.538 43.538 58.595 1.00 52.19 C ANISOU 509 C SER X 338 7616 4470 7744 2162 -804 422 C ATOM 510 O SER X 338 8.890 42.776 59.498 1.00 49.29 O ANISOU 510 O SER X 338 7043 4398 7287 2009 -622 213 O ATOM 511 CB SER X 338 10.138 45.386 57.975 1.00 55.85 C ANISOU 511 CB SER X 338 8732 4231 8254 1914 -689 621 C ATOM 512 OG SER X 338 11.253 44.797 58.623 1.00 52.95 O ANISOU 512 OG SER X 338 8274 4096 7748 1593 -452 449 O ATOM 513 N GLU X 339 7.891 43.126 57.507 1.00 52.81 N ANISOU 513 N GLU X 339 7715 4617 7730 2275 -1052 662 N ATOM 514 CA GLU X 339 7.513 41.727 57.316 1.00 50.05 C ANISOU 514 CA GLU X 339 7121 4694 7199 2216 -1107 665 C ATOM 515 C GLU X 339 8.504 40.986 56.421 1.00 47.86 C ANISOU 515 C GLU X 339 7068 4541 6574 1922 -1069 851 C ATOM 516 O GLU X 339 8.794 41.422 55.307 1.00 49.79 O ANISOU 516 O GLU X 339 7652 4584 6679 1884 -1181 1108 O ATOM 517 CB GLU X 339 6.097 41.625 56.742 1.00 52.51 C ANISOU 517 CB GLU X 339 7253 5051 7647 2518 -1423 751 C ATOM 518 N VAL X 340 9.029 39.873 56.927 1.00 44.25 N ANISOU 518 N VAL X 340 6437 4401 5974 1717 -899 718 N ATOM 519 CA VAL X 340 9.936 39.017 56.160 1.00 42.30 C ANISOU 519 CA VAL X 340 6335 4302 5435 1461 -835 835 C ATOM 520 C VAL X 340 9.517 37.552 56.244 1.00 39.88 C ANISOU 520 C VAL X 340 5773 4361 5019 1424 -872 763 C ATOM 521 O VAL X 340 8.952 37.118 57.250 1.00 38.87 O ANISOU 521 O VAL X 340 5348 4401 5019 1491 -830 583 O ATOM 522 CB VAL X 340 11.415 39.144 56.628 1.00 40.81 C ANISOU 522 CB VAL X 340 6234 4067 5204 1194 -561 746 C ATOM 523 CG1 VAL X 340 11.961 40.529 56.336 1.00 43.60 C ANISOU 523 CG1 VAL X 340 6887 4034 5644 1153 -506 844 C ATOM 524 CG2 VAL X 340 11.564 38.801 58.111 1.00 38.82 C ANISOU 524 CG2 VAL X 340 5704 3979 5065 1168 -425 473 C ATOM 525 N SER X 341 9.795 36.795 55.187 1.00 39.42 N ANISOU 525 N SER X 341 5854 4409 4714 1301 -930 898 N ATOM 526 CA SER X 341 9.615 35.348 55.223 1.00 37.22 C ANISOU 526 CA SER X 341 5381 4433 4328 1217 -936 819 C ATOM 527 C SER X 341 10.780 34.711 55.975 1.00 34.51 C ANISOU 527 C SER X 341 4965 4199 3949 1015 -679 682 C ATOM 528 O SER X 341 11.830 35.338 56.155 1.00 34.48 O ANISOU 528 O SER X 341 5085 4055 3958 905 -514 670 O ATOM 529 CB SER X 341 9.514 34.774 53.808 1.00 38.21 C ANISOU 529 CB SER X 341 5709 4616 4193 1159 -1093 976 C ATOM 530 OG SER X 341 10.784 34.715 53.185 1.00 37.91 O ANISOU 530 OG SER X 341 5935 4524 3944 948 -901 1037 O ATOM 531 N PHE X 342 10.591 33.469 56.415 1.00 32.67 N ANISOU 531 N PHE X 342 4523 4197 3690 964 -664 582 N ATOM 532 CA PHE X 342 11.651 32.731 57.099 1.00 30.59 C ANISOU 532 CA PHE X 342 4190 4034 3397 805 -481 471 C ATOM 533 C PHE X 342 12.847 32.493 56.177 1.00 30.59 C ANISOU 533 C PHE X 342 4380 3994 3249 644 -373 527 C ATOM 534 O PHE X 342 13.994 32.604 56.611 1.00 30.09 O ANISOU 534 O PHE X 342 4304 3899 3230 530 -211 455 O ATOM 535 CB PHE X 342 11.127 31.410 57.675 1.00 29.15 C ANISOU 535 CB PHE X 342 3795 4065 3214 787 -507 390 C ATOM 536 CG PHE X 342 10.109 31.586 58.770 1.00 29.47 C ANISOU 536 CG PHE X 342 3626 4171 3398 895 -518 301 C ATOM 537 CD1 PHE X 342 10.459 32.182 59.981 1.00 29.29 C ANISOU 537 CD1 PHE X 342 3561 4116 3451 902 -392 188 C ATOM 538 CD2 PHE X 342 8.800 31.148 58.595 1.00 30.37 C ANISOU 538 CD2 PHE X 342 3576 4389 3570 975 -643 307 C ATOM 539 CE1 PHE X 342 9.518 32.346 60.995 1.00 30.17 C ANISOU 539 CE1 PHE X 342 3500 4300 3664 991 -349 79 C ATOM 540 CE2 PHE X 342 7.850 31.307 59.601 1.00 31.17 C ANISOU 540 CE2 PHE X 342 3454 4566 3824 1060 -595 201 C ATOM 541 CZ PHE X 342 8.210 31.908 60.803 1.00 31.16 C ANISOU 541 CZ PHE X 342 3440 4533 3865 1070 -427 86 C ATOM 542 N LEU X 343 12.570 32.181 54.910 1.00 31.66 N ANISOU 542 N LEU X 343 4680 4139 3209 630 -461 638 N ATOM 543 CA LEU X 343 13.607 32.089 53.882 1.00 32.42 C ANISOU 543 CA LEU X 343 5000 4189 3129 474 -316 690 C ATOM 544 C LEU X 343 14.449 33.361 53.816 1.00 33.82 C ANISOU 544 C LEU X 343 5339 4159 3350 398 -161 749 C ATOM 545 O LEU X 343 15.678 33.296 53.846 1.00 33.62 O ANISOU 545 O LEU X 343 5305 4122 3347 238 63 680 O ATOM 546 CB LEU X 343 12.991 31.798 52.507 1.00 34.25 C ANISOU 546 CB LEU X 343 5457 4444 3110 482 -467 811 C ATOM 547 CG LEU X 343 13.267 30.447 51.839 1.00 33.88 C ANISOU 547 CG LEU X 343 5438 4547 2887 376 -423 730 C ATOM 548 CD1 LEU X 343 12.457 29.328 52.461 1.00 32.46 C ANISOU 548 CD1 LEU X 343 4997 4520 2814 438 -566 622 C ATOM 549 CD2 LEU X 343 12.969 30.536 50.353 1.00 36.65 C ANISOU 549 CD2 LEU X 343 6129 4877 2918 339 -526 857 C ATOM 550 N GLU X 344 13.779 34.509 53.737 1.00 35.63 N ANISOU 550 N GLU X 344 5697 4211 3629 514 -285 868 N ATOM 551 CA GLU X 344 14.449 35.807 53.662 1.00 37.61 C ANISOU 551 CA GLU X 344 6140 4206 3944 437 -156 942 C ATOM 552 C GLU X 344 15.243 36.104 54.926 1.00 36.33 C ANISOU 552 C GLU X 344 5768 4019 4014 367 -2 758 C ATOM 553 O GLU X 344 16.405 36.508 54.851 1.00 37.21 O ANISOU 553 O GLU X 344 5938 4034 4165 174 205 731 O ATOM 554 CB GLU X 344 13.438 36.928 53.425 1.00 40.05 C ANISOU 554 CB GLU X 344 6618 4294 4305 626 -367 1099 C ATOM 555 CG GLU X 344 12.843 36.962 52.031 1.00 42.92 C ANISOU 555 CG GLU X 344 7286 4611 4408 673 -553 1330 C ATOM 556 CD GLU X 344 11.610 37.842 51.950 1.00 45.85 C ANISOU 556 CD GLU X 344 7723 4804 4895 942 -860 1461 C ATOM 557 OE1 GLU X 344 10.735 37.564 51.100 1.00 47.73 O ANISOU 557 OE1 GLU X 344 8061 5099 4973 1059 -1137 1593 O ATOM 558 OE2 GLU X 344 11.514 38.810 52.737 1.00 46.59 O ANISOU 558 OE2 GLU X 344 7757 4692 5251 1045 -840 1414 O ATOM 559 N TYR X 345 14.609 35.897 56.079 1.00 34.75 N ANISOU 559 N TYR X 345 5326 3917 3960 505 -103 623 N ATOM 560 CA TYR X 345 15.218 36.201 57.370 1.00 33.90 C ANISOU 560 CA TYR X 345 5052 3798 4027 455 -10 437 C ATOM 561 C TYR X 345 16.585 35.543 57.538 1.00 33.03 C ANISOU 561 C TYR X 345 4832 3797 3918 256 145 334 C ATOM 562 O TYR X 345 17.580 36.231 57.754 1.00 34.17 O ANISOU 562 O TYR X 345 4990 3818 4174 109 271 270 O ATOM 563 CB TYR X 345 14.282 35.813 58.523 1.00 32.52 C ANISOU 563 CB TYR X 345 4661 3771 3925 614 -115 310 C ATOM 564 CG TYR X 345 14.856 36.086 59.897 1.00 31.76 C ANISOU 564 CG TYR X 345 4442 3686 3938 560 -45 111 C ATOM 565 CD1 TYR X 345 14.992 37.392 60.371 1.00 33.36 C ANISOU 565 CD1 TYR X 345 4732 3661 4280 567 -8 32 C ATOM 566 CD2 TYR X 345 15.265 35.040 60.723 1.00 29.65 C ANISOU 566 CD2 TYR X 345 4003 3638 3624 500 -39 1 C ATOM 567 CE1 TYR X 345 15.523 37.648 61.631 1.00 33.21 C ANISOU 567 CE1 TYR X 345 4627 3661 4329 501 30 -176 C ATOM 568 CE2 TYR X 345 15.797 35.285 61.985 1.00 29.64 C ANISOU 568 CE2 TYR X 345 3928 3659 3675 447 -22 -173 C ATOM 569 CZ TYR X 345 15.922 36.591 62.432 1.00 31.42 C ANISOU 569 CZ TYR X 345 4238 3684 4015 441 11 -275 C ATOM 570 OH TYR X 345 16.448 36.845 63.678 1.00 31.80 O ANISOU 570 OH TYR X 345 4237 3761 4084 374 6 -474 O ATOM 571 N TYR X 346 16.630 34.220 57.410 1.00 31.56 N ANISOU 571 N TYR X 346 4524 3826 3639 254 127 310 N ATOM 572 CA TYR X 346 17.849 33.457 57.677 1.00 31.09 C ANISOU 572 CA TYR X 346 4306 3875 3630 124 236 193 C ATOM 573 C TYR X 346 18.912 33.575 56.588 1.00 32.94 C ANISOU 573 C TYR X 346 4635 4043 3837 -50 443 226 C ATOM 574 O TYR X 346 20.092 33.333 56.841 1.00 33.42 O ANISOU 574 O TYR X 346 4529 4141 4027 -171 565 102 O ATOM 575 CB TYR X 346 17.510 31.995 57.962 1.00 29.20 C ANISOU 575 CB TYR X 346 3922 3840 3332 198 144 154 C ATOM 576 CG TYR X 346 16.695 31.836 59.218 1.00 27.98 C ANISOU 576 CG TYR X 346 3656 3767 3208 311 7 100 C ATOM 577 CD1 TYR X 346 17.301 31.870 60.471 1.00 27.58 C ANISOU 577 CD1 TYR X 346 3479 3755 3244 282 -12 -26 C ATOM 578 CD2 TYR X 346 15.313 31.676 59.158 1.00 27.43 C ANISOU 578 CD2 TYR X 346 3605 3743 3074 435 -97 166 C ATOM 579 CE1 TYR X 346 16.554 31.741 61.627 1.00 27.26 C ANISOU 579 CE1 TYR X 346 3386 3797 3174 362 -98 -77 C ATOM 580 CE2 TYR X 346 14.557 31.544 60.312 1.00 27.09 C ANISOU 580 CE2 TYR X 346 3450 3784 3056 513 -157 102 C ATOM 581 CZ TYR X 346 15.185 31.575 61.544 1.00 27.06 C ANISOU 581 CZ TYR X 346 3374 3818 3087 470 -139 -15 C ATOM 582 OH TYR X 346 14.447 31.442 62.697 1.00 27.45 O ANISOU 582 OH TYR X 346 3362 3961 3104 523 -163 -80 O ATOM 583 N ARG X 347 18.491 33.950 55.385 1.00 34.63 N ANISOU 583 N ARG X 347 5113 4163 3882 -66 483 389 N ATOM 584 CA ARG X 347 19.423 34.232 54.304 1.00 37.14 C ANISOU 584 CA ARG X 347 5588 4399 4122 -262 731 440 C ATOM 585 C ARG X 347 20.107 35.580 54.551 1.00 39.21 C ANISOU 585 C ARG X 347 5910 4441 4547 -411 863 445 C ATOM 586 O ARG X 347 21.325 35.698 54.420 1.00 40.69 O ANISOU 586 O ARG X 347 6003 4609 4848 -617 1100 355 O ATOM 587 CB ARG X 347 18.692 34.217 52.958 1.00 38.60 C ANISOU 587 CB ARG X 347 6105 4553 4009 -239 699 634 C ATOM 588 CG ARG X 347 19.581 34.393 51.733 1.00 41.88 C ANISOU 588 CG ARG X 347 6750 4910 4253 -462 995 697 C ATOM 589 CD ARG X 347 18.790 34.222 50.435 1.00 44.46 C ANISOU 589 CD ARG X 347 7442 5241 4208 -430 910 881 C ATOM 590 NE ARG X 347 17.556 35.012 50.418 1.00 45.60 N ANISOU 590 NE ARG X 347 7778 5248 4297 -257 604 1074 N ATOM 591 CZ ARG X 347 17.472 36.287 50.042 1.00 48.69 C ANISOU 591 CZ ARG X 347 8468 5381 4649 -297 606 1274 C ATOM 592 NH1 ARG X 347 18.553 36.948 49.641 1.00 51.29 N ANISOU 592 NH1 ARG X 347 8959 5561 4965 -548 926 1318 N ATOM 593 NH2 ARG X 347 16.299 36.905 50.069 1.00 49.40 N ANISOU 593 NH2 ARG X 347 8684 5344 4739 -85 290 1428 N ATOM 594 N LYS X 348 19.317 36.583 54.928 1.00 39.80 N ANISOU 594 N LYS X 348 6117 4338 4667 -307 714 527 N ATOM 595 CA LYS X 348 19.825 37.936 55.166 1.00 42.23 C ANISOU 595 CA LYS X 348 6527 4377 5139 -442 815 532 C ATOM 596 C LYS X 348 20.583 38.075 56.489 1.00 41.63 C ANISOU 596 C LYS X 348 6153 4333 5329 -511 819 287 C ATOM 597 O LYS X 348 21.619 38.742 56.547 1.00 43.70 O ANISOU 597 O LYS X 348 6385 4462 5755 -739 991 214 O ATOM 598 CB LYS X 348 18.684 38.958 55.112 1.00 43.48 C ANISOU 598 CB LYS X 348 6938 4297 5284 -270 636 687 C ATOM 599 CG LYS X 348 18.155 39.243 53.715 1.00 46.03 C ANISOU 599 CG LYS X 348 7639 4490 5359 -253 616 969 C ATOM 600 CD LYS X 348 16.930 40.149 53.762 1.00 48.01 C ANISOU 600 CD LYS X 348 8075 4511 5652 -11 365 1109 C ATOM 601 CE LYS X 348 16.431 40.484 52.362 1.00 51.16 C ANISOU 601 CE LYS X 348 8889 4762 5786 14 281 1419 C ATOM 602 NZ LYS X 348 15.062 41.071 52.379 1.00 52.46 N ANISOU 602 NZ LYS X 348 9152 4768 6010 329 -49 1544 N ATOM 603 N GLN X 349 20.066 37.443 57.542 1.00 39.26 N ANISOU 603 N GLN X 349 5646 4211 5059 -335 627 160 N ATOM 604 CA GLN X 349 20.590 37.630 58.895 1.00 39.07 C ANISOU 604 CA GLN X 349 5404 4220 5220 -371 563 -62 C ATOM 605 C GLN X 349 21.791 36.742 59.220 1.00 38.80 C ANISOU 605 C GLN X 349 5078 4380 5281 -492 608 -214 C ATOM 606 O GLN X 349 22.747 37.196 59.854 1.00 40.27 O ANISOU 606 O GLN X 349 5114 4524 5662 -644 627 -378 O ATOM 607 CB GLN X 349 19.477 37.427 59.933 1.00 37.35 C ANISOU 607 CB GLN X 349 5139 4096 4955 -144 358 -125 C ATOM 608 CG GLN X 349 19.811 37.926 61.334 1.00 37.75 C ANISOU 608 CG GLN X 349 5081 4130 5130 -176 283 -349 C ATOM 609 CD GLN X 349 20.064 39.419 61.386 1.00 40.51 C ANISOU 609 CD GLN X 349 5585 4165 5638 -284 352 -401 C ATOM 610 OE1 GLN X 349 21.182 39.858 61.652 1.00 42.16 O ANISOU 610 OE1 GLN X 349 5715 4301 6003 -499 412 -532 O ATOM 611 NE2 GLN X 349 19.026 40.209 61.121 1.00 41.39 N ANISOU 611 NE2 GLN X 349 5907 4072 5744 -135 332 -304 N ATOM 612 N TYR X 350 21.735 35.483 58.790 1.00 37.38 N ANISOU 612 N TYR X 350 4811 4398 4990 -417 604 -173 N ATOM 613 CA TYR X 350 22.752 34.496 59.149 1.00 37.22 C ANISOU 613 CA TYR X 350 4499 4554 5088 -460 601 -316 C ATOM 614 C TYR X 350 23.371 33.785 57.946 1.00 38.13 C ANISOU 614 C TYR X 350 4580 4726 5181 -537 816 -284 C ATOM 615 O TYR X 350 24.241 32.926 58.116 1.00 38.54 O ANISOU 615 O TYR X 350 4369 4903 5371 -546 831 -413 O ATOM 616 CB TYR X 350 22.160 33.442 60.088 1.00 34.95 C ANISOU 616 CB TYR X 350 4108 4448 4721 -269 367 -349 C ATOM 617 CG TYR X 350 21.558 33.976 61.370 1.00 34.51 C ANISOU 617 CG TYR X 350 4083 4383 4644 -194 188 -413 C ATOM 618 CD1 TYR X 350 20.177 34.131 61.500 1.00 33.18 C ANISOU 618 CD1 TYR X 350 4078 4203 4324 -47 125 -323 C ATOM 619 CD2 TYR X 350 22.364 34.302 62.461 1.00 35.63 C ANISOU 619 CD2 TYR X 350 4078 4539 4917 -272 81 -588 C ATOM 620 CE1 TYR X 350 19.615 34.607 62.678 1.00 33.16 C ANISOU 620 CE1 TYR X 350 4101 4202 4296 18 17 -416 C ATOM 621 CE2 TYR X 350 21.811 34.779 63.644 1.00 35.65 C ANISOU 621 CE2 TYR X 350 4151 4544 4850 -215 -60 -675 C ATOM 622 CZ TYR X 350 20.437 34.929 63.745 1.00 34.45 C ANISOU 622 CZ TYR X 350 4170 4378 4539 -69 -64 -593 C ATOM 623 OH TYR X 350 19.887 35.400 64.913 1.00 34.89 O ANISOU 623 OH TYR X 350 4291 4442 4522 -16 -150 -711 O ATOM 624 N ASN X 351 22.926 34.141 56.740 1.00 39.05 N ANISOU 624 N ASN X 351 4973 4745 5118 -583 972 -122 N ATOM 625 CA ASN X 351 23.307 33.431 55.512 1.00 40.11 C ANISOU 625 CA ASN X 351 5157 4944 5138 -649 1192 -92 C ATOM 626 C ASN X 351 23.109 31.915 55.646 1.00 38.41 C ANISOU 626 C ASN X 351 4790 4919 4882 -483 1074 -161 C ATOM 627 O ASN X 351 24.007 31.118 55.361 1.00 39.26 O ANISOU 627 O ASN X 351 4703 5111 5100 -520 1217 -292 O ATOM 628 CB ASN X 351 24.737 33.790 55.076 1.00 43.05 C ANISOU 628 CB ASN X 351 5381 5273 5700 -899 1509 -204 C ATOM 629 CG ASN X 351 25.038 33.387 53.636 1.00 44.80 C ANISOU 629 CG ASN X 351 5761 5522 5738 -1010 1823 -158 C ATOM 630 OD1 ASN X 351 24.169 33.439 52.763 1.00 44.71 O ANISOU 630 OD1 ASN X 351 6108 5472 5406 -973 1821 22 O ATOM 631 ND2 ASN X 351 26.279 32.991 53.386 1.00 46.55 N ANISOU 631 ND2 ASN X 351 5709 5816 6160 -1147 2092 -339 N ATOM 632 N GLN X 352 21.919 31.540 56.108 1.00 36.47 N ANISOU 632 N GLN X 352 4623 4722 4509 -301 823 -84 N ATOM 633 CA GLN X 352 21.522 30.145 56.226 1.00 35.15 C ANISOU 633 CA GLN X 352 4375 4692 4288 -161 698 -115 C ATOM 634 C GLN X 352 20.399 29.856 55.238 1.00 35.10 C ANISOU 634 C GLN X 352 4629 4694 4012 -106 664 18 C ATOM 635 O GLN X 352 19.288 30.378 55.371 1.00 34.43 O ANISOU 635 O GLN X 352 4680 4574 3826 -29 508 136 O ATOM 636 CB GLN X 352 21.087 29.821 57.660 1.00 33.35 C ANISOU 636 CB GLN X 352 4003 4528 4138 -34 443 -148 C ATOM 637 CG GLN X 352 22.230 29.787 58.678 1.00 33.84 C ANISOU 637 CG GLN X 352 3800 4617 4438 -65 396 -296 C ATOM 638 CD GLN X 352 23.216 28.651 58.441 1.00 34.42 C ANISOU 638 CD GLN X 352 3664 4752 4659 -45 450 -408 C ATOM 639 OE1 GLN X 352 22.839 27.560 58.014 1.00 33.65 O ANISOU 639 OE1 GLN X 352 3610 4693 4482 43 435 -385 O ATOM 640 NE2 GLN X 352 24.487 28.906 58.724 1.00 36.24 N ANISOU 640 NE2 GLN X 352 3647 4980 5142 -126 507 -549 N ATOM 641 N GLU X 353 20.709 29.033 54.240 1.00 36.37 N ANISOU 641 N GLU X 353 4847 4901 4072 -143 803 -23 N ATOM 642 CA GLU X 353 19.774 28.718 53.165 1.00 37.12 C ANISOU 642 CA GLU X 353 5210 5012 3881 -123 762 75 C ATOM 643 C GLU X 353 18.924 27.504 53.531 1.00 35.42 C ANISOU 643 C GLU X 353 4921 4887 3650 8 545 45 C ATOM 644 O GLU X 353 19.438 26.392 53.670 1.00 35.32 O ANISOU 644 O GLU X 353 4766 4914 3736 33 583 -85 O ATOM 645 CB GLU X 353 20.523 28.469 51.847 1.00 39.74 C ANISOU 645 CB GLU X 353 5693 5345 4060 -258 1050 19 C ATOM 646 CG GLU X 353 21.611 29.504 51.499 1.00 43.01 C ANISOU 646 CG GLU X 353 6135 5674 4533 -444 1353 19 C ATOM 647 CD GLU X 353 21.058 30.861 51.063 1.00 45.43 C ANISOU 647 CD GLU X 353 6757 5843 4660 -514 1328 240 C ATOM 648 OE1 GLU X 353 21.754 31.879 51.283 1.00 47.04 O ANISOU 648 OE1 GLU X 353 6935 5931 5006 -647 1483 260 O ATOM 649 OE2 GLU X 353 19.940 30.914 50.500 1.00 45.93 O ANISOU 649 OE2 GLU X 353 7090 5898 4463 -436 1135 392 O ATOM 650 N ILE X 354 17.625 27.734 53.702 1.00 34.61 N ANISOU 650 N ILE X 354 4900 4794 3453 90 322 161 N ATOM 651 CA ILE X 354 16.670 26.665 53.975 1.00 33.52 C ANISOU 651 CA ILE X 354 4702 4734 3299 172 130 146 C ATOM 652 C ILE X 354 16.287 26.010 52.653 1.00 35.11 C ANISOU 652 C ILE X 354 5106 4960 3272 130 122 135 C ATOM 653 O ILE X 354 15.795 26.680 51.742 1.00 36.66 O ANISOU 653 O ILE X 354 5530 5138 3260 106 78 240 O ATOM 654 CB ILE X 354 15.407 27.190 54.699 1.00 32.55 C ANISOU 654 CB ILE X 354 4531 4630 3207 265 -77 242 C ATOM 655 CG1 ILE X 354 15.783 27.831 56.041 1.00 31.54 C ANISOU 655 CG1 ILE X 354 4241 4480 3261 296 -58 218 C ATOM 656 CG2 ILE X 354 14.395 26.066 54.903 1.00 31.88 C ANISOU 656 CG2 ILE X 354 4367 4626 3118 302 -238 223 C ATOM 657 CD1 ILE X 354 14.739 28.785 56.598 1.00 31.28 C ANISOU 657 CD1 ILE X 354 4198 4428 3259 384 -174 286 C ATOM 658 N THR X 355 16.517 24.703 52.555 1.00 35.27 N ANISOU 658 N THR X 355 5069 5007 3324 124 146 7 N ATOM 659 CA THR X 355 16.297 23.964 51.310 1.00 37.11 C ANISOU 659 CA THR X 355 5507 5257 3337 67 162 -63 C ATOM 660 C THR X 355 14.917 23.308 51.239 1.00 37.14 C ANISOU 660 C THR X 355 5532 5306 3274 91 -111 -39 C ATOM 661 O THR X 355 14.293 23.285 50.177 1.00 38.90 O ANISOU 661 O THR X 355 5969 5559 3250 47 -215 -27 O ATOM 662 CB THR X 355 17.392 22.900 51.078 1.00 37.91 C ANISOU 662 CB THR X 355 5550 5326 3527 46 373 -262 C ATOM 663 OG1 THR X 355 17.398 21.971 52.168 1.00 36.42 O ANISOU 663 OG1 THR X 355 5136 5106 3596 127 268 -312 O ATOM 664 CG2 THR X 355 18.766 23.552 50.963 1.00 38.87 C ANISOU 664 CG2 THR X 355 5615 5422 3731 -3 669 -315 C ATOM 665 N ASP X 356 14.452 22.777 52.370 1.00 35.79 N ANISOU 665 N ASP X 356 5143 5140 3312 143 -230 -36 N ATOM 666 CA ASP X 356 13.173 22.068 52.439 1.00 36.16 C ANISOU 666 CA ASP X 356 5149 5226 3361 130 -452 -32 C ATOM 667 C ASP X 356 12.028 23.027 52.747 1.00 36.10 C ANISOU 667 C ASP X 356 5069 5285 3362 183 -632 102 C ATOM 668 O ASP X 356 12.008 23.664 53.800 1.00 34.88 O ANISOU 668 O ASP X 356 4763 5134 3353 245 -605 165 O ATOM 669 CB ASP X 356 13.235 20.953 53.491 1.00 35.16 C ANISOU 669 CB ASP X 356 4852 5055 3450 130 -453 -83 C ATOM 670 CG ASP X 356 12.114 19.930 53.341 1.00 36.21 C ANISOU 670 CG ASP X 356 4972 5192 3593 54 -622 -122 C ATOM 671 OD1 ASP X 356 11.302 20.035 52.394 1.00 37.98 O ANISOU 671 OD1 ASP X 356 5292 5472 3664 8 -766 -138 O ATOM 672 OD2 ASP X 356 12.050 19.007 54.178 1.00 35.94 O ANISOU 672 OD2 ASP X 356 4840 5093 3720 29 -625 -134 O ATOM 673 N LEU X 357 11.074 23.111 51.823 1.00 38.04 N ANISOU 673 N LEU X 357 5420 5578 3455 167 -830 125 N ATOM 674 CA LEU X 357 9.964 24.063 51.921 1.00 38.96 C ANISOU 674 CA LEU X 357 5455 5743 3603 254 -1033 241 C ATOM 675 C LEU X 357 8.678 23.464 52.500 1.00 39.39 C ANISOU 675 C LEU X 357 5252 5876 3837 244 -1209 208 C ATOM 676 O LEU X 357 7.738 24.196 52.823 1.00 40.04 O ANISOU 676 O LEU X 357 5174 6006 4034 337 -1345 271 O ATOM 677 CB LEU X 357 9.678 24.683 50.546 1.00 41.43 C ANISOU 677 CB LEU X 357 6037 6057 3648 265 -1196 314 C ATOM 678 CG LEU X 357 10.422 25.947 50.096 1.00 42.04 C ANISOU 678 CG LEU X 357 6347 6047 3579 303 -1082 443 C ATOM 679 CD1 LEU X 357 11.936 25.768 50.059 1.00 41.30 C ANISOU 679 CD1 LEU X 357 6358 5896 3436 210 -739 373 C ATOM 680 CD2 LEU X 357 9.912 26.374 48.730 1.00 45.17 C ANISOU 680 CD2 LEU X 357 7050 6446 3667 304 -1307 543 C ATOM 681 N LYS X 358 8.643 22.139 52.632 1.00 39.51 N ANISOU 681 N LYS X 358 5220 5888 3902 129 -1188 100 N ATOM 682 CA LYS X 358 7.445 21.432 53.094 1.00 40.46 C ANISOU 682 CA LYS X 358 5107 6069 4194 58 -1322 60 C ATOM 683 C LYS X 358 7.435 21.177 54.603 1.00 38.99 C ANISOU 683 C LYS X 358 4714 5879 4218 43 -1155 83 C ATOM 684 O LYS X 358 6.435 20.697 55.149 1.00 39.98 O ANISOU 684 O LYS X 358 4629 6060 4500 -36 -1200 64 O ATOM 685 CB LYS X 358 7.272 20.114 52.331 1.00 42.01 C ANISOU 685 CB LYS X 358 5402 6234 4325 -93 -1415 -71 C ATOM 686 CG LYS X 358 6.865 20.288 50.878 1.00 44.66 C ANISOU 686 CG LYS X 358 5925 6616 4426 -108 -1655 -111 C ATOM 687 CD LYS X 358 6.910 18.969 50.128 1.00 46.80 C ANISOU 687 CD LYS X 358 6347 6832 4602 -269 -1707 -287 C ATOM 688 CE LYS X 358 6.736 19.191 48.633 1.00 50.02 C ANISOU 688 CE LYS X 358 7032 7291 4680 -289 -1923 -337 C ATOM 689 NZ LYS X 358 6.776 17.915 47.867 1.00 52.48 N ANISOU 689 NZ LYS X 358 7520 7544 4876 -454 -1970 -553 N ATOM 690 N GLN X 359 8.543 21.503 55.267 1.00 37.13 N ANISOU 690 N GLN X 359 4544 5586 3977 101 -963 121 N ATOM 691 CA GLN X 359 8.681 21.299 56.712 1.00 35.97 C ANISOU 691 CA GLN X 359 4272 5434 3957 88 -823 154 C ATOM 692 C GLN X 359 7.805 22.251 57.538 1.00 36.20 C ANISOU 692 C GLN X 359 4106 5563 4084 155 -810 194 C ATOM 693 O GLN X 359 7.554 23.384 57.117 1.00 36.53 O ANISOU 693 O GLN X 359 4136 5631 4114 273 -877 215 O ATOM 694 CB GLN X 359 10.151 21.409 57.141 1.00 34.42 C ANISOU 694 CB GLN X 359 4191 5157 3730 140 -678 164 C ATOM 695 CG GLN X 359 10.808 22.749 56.852 1.00 33.75 C ANISOU 695 CG GLN X 359 4170 5072 3581 245 -631 189 C ATOM 696 CD GLN X 359 12.278 22.768 57.214 1.00 32.88 C ANISOU 696 CD GLN X 359 4117 4890 3483 266 -500 167 C ATOM 697 OE1 GLN X 359 12.653 22.477 58.348 1.00 32.54 O ANISOU 697 OE1 GLN X 359 4009 4839 3516 269 -462 178 O ATOM 698 NE2 GLN X 359 13.120 23.118 56.250 1.00 33.06 N ANISOU 698 NE2 GLN X 359 4261 4869 3430 274 -434 134 N ATOM 699 N PRO X 360 7.336 21.790 58.717 1.00 36.46 N ANISOU 699 N PRO X 360 4004 5635 4212 78 -707 203 N ATOM 700 CA PRO X 360 6.556 22.648 59.606 1.00 37.10 C ANISOU 700 CA PRO X 360 3897 5816 4383 137 -629 201 C ATOM 701 C PRO X 360 7.457 23.635 60.340 1.00 35.86 C ANISOU 701 C PRO X 360 3831 5631 4163 248 -514 216 C ATOM 702 O PRO X 360 8.675 23.590 60.180 1.00 34.53 O ANISOU 702 O PRO X 360 3835 5378 3906 264 -505 236 O ATOM 703 CB PRO X 360 5.953 21.652 60.596 1.00 38.10 C ANISOU 703 CB PRO X 360 3921 5983 4572 -32 -506 207 C ATOM 704 CG PRO X 360 6.964 20.569 60.679 1.00 37.13 C ANISOU 704 CG PRO X 360 4012 5732 4361 -118 -493 255 C ATOM 705 CD PRO X 360 7.519 20.440 59.288 1.00 36.62 C ANISOU 705 CD PRO X 360 4071 5592 4251 -70 -641 217 C ATOM 706 N VAL X 361 6.862 24.520 61.133 1.00 36.77 N ANISOU 706 N VAL X 361 3812 5814 4344 320 -424 181 N ATOM 707 CA VAL X 361 7.638 25.464 61.933 1.00 36.17 C ANISOU 707 CA VAL X 361 3825 5705 4209 403 -319 161 C ATOM 708 C VAL X 361 7.395 25.209 63.419 1.00 37.01 C ANISOU 708 C VAL X 361 3896 5894 4272 323 -141 133 C ATOM 709 O VAL X 361 6.251 25.185 63.874 1.00 38.73 O ANISOU 709 O VAL X 361 3930 6212 4572 291 -38 84 O ATOM 710 CB VAL X 361 7.329 26.944 61.569 1.00 36.81 C ANISOU 710 CB VAL X 361 3860 5748 4378 578 -358 122 C ATOM 711 CG1 VAL X 361 8.281 27.876 62.290 1.00 36.12 C ANISOU 711 CG1 VAL X 361 3898 5589 4234 630 -264 82 C ATOM 712 CG2 VAL X 361 7.437 27.170 60.067 1.00 36.71 C ANISOU 712 CG2 VAL X 361 3933 5658 4357 637 -544 185 C ATOM 713 N LEU X 362 8.481 25.000 64.158 1.00 36.35 N ANISOU 713 N LEU X 362 3985 5773 4051 282 -106 159 N ATOM 714 CA LEU X 362 8.422 24.791 65.603 1.00 37.63 C ANISOU 714 CA LEU X 362 4202 6008 4087 199 37 151 C ATOM 715 C LEU X 362 8.164 26.122 66.306 1.00 38.74 C ANISOU 715 C LEU X 362 4302 6196 4222 296 156 23 C ATOM 716 O LEU X 362 8.594 27.173 65.827 1.00 38.18 O ANISOU 716 O LEU X 362 4241 6045 4219 424 92 -32 O ATOM 717 CB LEU X 362 9.736 24.184 66.112 1.00 36.88 C ANISOU 717 CB LEU X 362 4315 5847 3850 154 -40 225 C ATOM 718 CG LEU X 362 10.431 23.078 65.308 1.00 35.89 C ANISOU 718 CG LEU X 362 4256 5611 3767 125 -180 314 C ATOM 719 CD1 LEU X 362 11.868 22.899 65.788 1.00 35.37 C ANISOU 719 CD1 LEU X 362 4331 5474 3631 157 -283 341 C ATOM 720 CD2 LEU X 362 9.667 21.757 65.366 1.00 36.87 C ANISOU 720 CD2 LEU X 362 4380 5726 3902 -18 -151 400 C ATOM 721 N VAL X 363 7.467 26.076 67.438 1.00 40.83 N ANISOU 721 N VAL X 363 4540 6573 4400 223 352 -32 N ATOM 722 CA VAL X 363 7.162 27.292 68.198 1.00 42.49 C ANISOU 722 CA VAL X 363 4721 6824 4597 313 504 -199 C ATOM 723 C VAL X 363 7.595 27.193 69.662 1.00 44.05 C ANISOU 723 C VAL X 363 5133 7095 4506 206 630 -234 C ATOM 724 O VAL X 363 7.302 26.207 70.343 1.00 45.38 O ANISOU 724 O VAL X 363 5380 7347 4512 42 735 -147 O ATOM 725 CB VAL X 363 5.665 27.753 68.026 1.00 44.52 C ANISOU 725 CB VAL X 363 4680 7158 5074 387 657 -315 C ATOM 726 CG1 VAL X 363 4.770 26.608 67.574 1.00 45.24 C ANISOU 726 CG1 VAL X 363 4592 7325 5271 258 668 -227 C ATOM 727 CG2 VAL X 363 5.115 28.422 69.286 1.00 47.08 C ANISOU 727 CG2 VAL X 363 4983 7581 5323 393 942 -502 C ATOM 728 N SER X 364 8.316 28.215 70.120 1.00 44.40 N ANISOU 728 N SER X 364 5301 7093 4476 286 603 -356 N ATOM 729 CA SER X 364 8.814 28.284 71.490 1.00 46.35 C ANISOU 729 CA SER X 364 5785 7410 4416 195 669 -420 C ATOM 730 C SER X 364 8.271 29.530 72.191 1.00 48.91 C ANISOU 730 C SER X 364 6088 7768 4725 271 882 -676 C ATOM 731 O SER X 364 8.458 30.649 71.709 1.00 48.45 O ANISOU 731 O SER X 364 5965 7586 4858 419 826 -800 O ATOM 732 CB SER X 364 10.345 28.294 71.490 1.00 44.87 C ANISOU 732 CB SER X 364 5775 7131 4141 197 400 -368 C ATOM 733 OG SER X 364 10.863 28.289 72.808 1.00 46.88 O ANISOU 733 OG SER X 364 6275 7461 4075 107 390 -418 O ATOM 734 N GLN X 365 7.598 29.327 73.323 1.00 52.13 N ANISOU 734 N GLN X 365 6573 8327 4904 161 1144 -757 N ATOM 735 CA GLN X 365 6.998 30.427 74.090 1.00 55.34 C ANISOU 735 CA GLN X 365 6966 8780 5281 228 1408 -1044 C ATOM 736 C GLN X 365 7.942 30.957 75.172 1.00 56.93 C ANISOU 736 C GLN X 365 7499 8987 5145 173 1355 -1179 C ATOM 737 O GLN X 365 8.537 30.170 75.911 1.00 57.60 O ANISOU 737 O GLN X 365 7849 9156 4880 12 1267 -1052 O ATOM 738 CB GLN X 365 5.668 29.996 74.724 1.00 58.51 C ANISOU 738 CB GLN X 365 7245 9361 5622 126 1792 -1110 C ATOM 739 CG GLN X 365 4.560 29.632 73.730 1.00 58.34 C ANISOU 739 CG GLN X 365 6829 9352 5985 182 1855 -1048 C ATOM 740 CD GLN X 365 4.004 30.828 72.963 1.00 58.76 C ANISOU 740 CD GLN X 365 6586 9292 6445 452 1840 -1230 C ATOM 741 OE1 GLN X 365 4.208 31.985 73.341 1.00 59.80 O ANISOU 741 OE1 GLN X 365 6791 9340 6589 589 1893 -1448 O ATOM 742 NE2 GLN X 365 3.289 30.546 71.878 1.00 58.07 N ANISOU 742 NE2 GLN X 365 6182 9184 6696 529 1745 -1141 N ATOM 743 N PRO X 366 8.077 32.297 75.271 1.00 58.06 N ANISOU 743 N PRO X 366 7640 9021 5397 306 1383 -1438 N ATOM 744 CA PRO X 366 8.957 32.926 76.255 1.00 59.89 C ANISOU 744 CA PRO X 366 8173 9243 5337 247 1310 -1619 C ATOM 745 C PRO X 366 8.227 33.339 77.540 1.00 64.39 C ANISOU 745 C PRO X 366 8891 9955 5619 191 1668 -1896 C ATOM 746 O PRO X 366 7.076 32.947 77.749 1.00 66.16 O ANISOU 746 O PRO X 366 8980 10314 5843 164 1998 -1912 O ATOM 747 CB PRO X 366 9.470 34.161 75.507 1.00 58.68 C ANISOU 747 CB PRO X 366 7931 8847 5517 408 1156 -1752 C ATOM 748 CG PRO X 366 8.389 34.482 74.485 1.00 57.99 C ANISOU 748 CG PRO X 366 7518 8670 5843 594 1287 -1739 C ATOM 749 CD PRO X 366 7.444 33.304 74.399 1.00 57.83 C ANISOU 749 CD PRO X 366 7340 8839 5793 526 1439 -1568 C ATOM 750 N LYS X 367 8.910 34.120 78.381 1.00 66.63 N ANISOU 750 N LYS X 367 9443 10210 5663 156 1611 -2131 N ATOM 751 CA LYS X 367 8.374 34.649 79.648 1.00 71.41 C ANISOU 751 CA LYS X 367 10255 10936 5940 97 1946 -2454 C ATOM 752 C LYS X 367 7.708 33.605 80.550 1.00 74.11 C ANISOU 752 C LYS X 367 10757 11544 5855 -99 2229 -2354 C ATOM 753 O LYS X 367 6.488 33.423 80.533 1.00 75.70 O ANISOU 753 O LYS X 367 10742 11842 6177 -84 2621 -2403 O ATOM 754 CB LYS X 367 7.433 35.841 79.403 1.00 73.17 C ANISOU 754 CB LYS X 367 10235 11030 6534 310 2247 -2779 C ATOM 755 CG LYS X 367 8.145 37.160 79.132 1.00 73.14 C ANISOU 755 CG LYS X 367 10277 10752 6760 441 2052 -3003 C ATOM 756 CD LYS X 367 7.151 38.311 79.023 1.00 75.90 C ANISOU 756 CD LYS X 367 10428 10945 7464 672 2361 -3333 C ATOM 757 CE LYS X 367 7.841 39.626 78.683 1.00 75.96 C ANISOU 757 CE LYS X 367 10504 10617 7739 793 2164 -3529 C ATOM 758 NZ LYS X 367 8.601 40.190 79.834 1.00 79.08 N ANISOU 758 NZ LYS X 367 11281 11013 7751 644 2137 -3837 N ATOM 759 N GLY X 378 4.271 36.544 71.896 1.00 54.07 N ANISOU 759 N GLY X 378 5898 7834 6809 1424 1635 -1985 N ATOM 760 CA GLY X 378 5.199 36.599 70.769 1.00 50.73 C ANISOU 760 CA GLY X 378 5592 7229 6453 1432 1280 -1735 C ATOM 761 C GLY X 378 6.221 35.475 70.793 1.00 47.54 C ANISOU 761 C GLY X 378 5375 6955 5729 1178 1138 -1513 C ATOM 762 O GLY X 378 7.335 35.664 71.286 1.00 46.87 O ANISOU 762 O GLY X 378 5548 6825 5433 1063 1065 -1546 O ATOM 763 N PRO X 379 5.853 34.296 70.253 1.00 45.95 N ANISOU 763 N PRO X 379 5032 6903 5521 1095 1080 -1300 N ATOM 764 CA PRO X 379 6.744 33.137 70.283 1.00 43.40 C ANISOU 764 CA PRO X 379 4873 6681 4934 881 952 -1095 C ATOM 765 C PRO X 379 7.812 33.168 69.191 1.00 40.56 C ANISOU 765 C PRO X 379 4610 6161 4638 888 665 -917 C ATOM 766 O PRO X 379 7.655 33.868 68.188 1.00 40.42 O ANISOU 766 O PRO X 379 4521 5978 4858 1037 556 -882 O ATOM 767 CB PRO X 379 5.791 31.965 70.055 1.00 43.48 C ANISOU 767 CB PRO X 379 4677 6864 4977 803 1026 -972 C ATOM 768 CG PRO X 379 4.686 32.533 69.231 1.00 44.76 C ANISOU 768 CG PRO X 379 4535 6968 5502 1006 1021 -1025 C ATOM 769 CD PRO X 379 4.571 33.991 69.586 1.00 46.92 C ANISOU 769 CD PRO X 379 4821 7092 5914 1203 1111 -1258 C ATOM 770 N ALA X 380 8.889 32.415 69.398 1.00 38.88 N ANISOU 770 N ALA X 380 4564 5993 4212 730 550 -804 N ATOM 771 CA ALA X 380 9.933 32.264 68.390 1.00 36.54 C ANISOU 771 CA ALA X 380 4327 5579 3975 710 331 -651 C ATOM 772 C ALA X 380 9.603 31.080 67.490 1.00 35.04 C ANISOU 772 C ALA X 380 4034 5456 3822 674 252 -454 C ATOM 773 O ALA X 380 9.329 29.977 67.970 1.00 35.20 O ANISOU 773 O ALA X 380 4047 5615 3712 565 298 -389 O ATOM 774 CB ALA X 380 11.297 32.079 69.047 1.00 36.03 C ANISOU 774 CB ALA X 380 4441 5520 3725 585 230 -664 C ATOM 775 N MET X 381 9.617 31.318 66.183 1.00 34.09 N ANISOU 775 N MET X 381 3866 5222 3864 752 134 -361 N ATOM 776 CA MET X 381 9.297 30.279 65.215 1.00 33.04 C ANISOU 776 CA MET X 381 3657 5136 3759 717 41 -208 C ATOM 777 C MET X 381 10.586 29.694 64.646 1.00 31.27 C ANISOU 777 C MET X 381 3558 4859 3463 631 -72 -107 C ATOM 778 O MET X 381 11.341 30.379 63.953 1.00 30.87 O ANISOU 778 O MET X 381 3585 4679 3464 658 -125 -94 O ATOM 779 CB MET X 381 8.401 30.830 64.101 1.00 33.82 C ANISOU 779 CB MET X 381 3641 5166 4043 859 -37 -174 C ATOM 780 CG MET X 381 7.132 31.532 64.582 1.00 36.42 C ANISOU 780 CG MET X 381 3785 5524 4529 995 62 -302 C ATOM 781 SD MET X 381 6.059 30.508 65.611 1.00 38.25 S ANISOU 781 SD MET X 381 3816 5992 4725 884 259 -373 S ATOM 782 CE MET X 381 5.306 29.444 64.381 1.00 38.39 C ANISOU 782 CE MET X 381 3661 6073 4851 840 87 -235 C ATOM 783 N LEU X 382 10.831 28.423 64.950 1.00 30.63 N ANISOU 783 N LEU X 382 3494 4862 3279 523 -90 -41 N ATOM 784 CA LEU X 382 12.090 27.776 64.597 1.00 29.46 C ANISOU 784 CA LEU X 382 3431 4664 3096 464 -183 19 C ATOM 785 C LEU X 382 11.935 26.788 63.446 1.00 28.86 C ANISOU 785 C LEU X 382 3333 4573 3058 439 -247 112 C ATOM 786 O LEU X 382 10.961 26.034 63.386 1.00 29.28 O ANISOU 786 O LEU X 382 3322 4690 3114 403 -240 151 O ATOM 787 CB LEU X 382 12.683 27.067 65.817 1.00 29.81 C ANISOU 787 CB LEU X 382 3550 4768 3007 387 -203 23 C ATOM 788 CG LEU X 382 12.823 27.858 67.120 1.00 30.74 C ANISOU 788 CG LEU X 382 3737 4930 3012 380 -156 -87 C ATOM 789 CD1 LEU X 382 12.919 26.898 68.287 1.00 31.56 C ANISOU 789 CD1 LEU X 382 3951 5123 2916 291 -180 -31 C ATOM 790 CD2 LEU X 382 14.020 28.799 67.084 1.00 30.39 C ANISOU 790 CD2 LEU X 382 3726 4795 3025 397 -229 -179 C ATOM 791 N ILE X 383 12.911 26.805 62.541 1.00 28.31 N ANISOU 791 N ILE X 383 3317 4419 3020 441 -290 127 N ATOM 792 CA ILE X 383 12.947 25.900 61.396 1.00 28.09 C ANISOU 792 CA ILE X 383 3308 4365 2998 414 -333 176 C ATOM 793 C ILE X 383 13.715 24.627 61.768 1.00 28.00 C ANISOU 793 C ILE X 383 3315 4339 2984 364 -364 188 C ATOM 794 O ILE X 383 14.889 24.697 62.141 1.00 27.99 O ANISOU 794 O ILE X 383 3319 4301 3015 373 -374 154 O ATOM 795 CB ILE X 383 13.562 26.586 60.138 1.00 28.14 C ANISOU 795 CB ILE X 383 3390 4287 3013 432 -316 175 C ATOM 796 CG1 ILE X 383 12.551 27.533 59.482 1.00 29.00 C ANISOU 796 CG1 ILE X 383 3521 4378 3117 497 -352 214 C ATOM 797 CG2 ILE X 383 14.011 25.553 59.104 1.00 28.18 C ANISOU 797 CG2 ILE X 383 3448 4266 2989 386 -321 177 C ATOM 798 CD1 ILE X 383 12.426 28.888 60.141 1.00 29.31 C ANISOU 798 CD1 ILE X 383 3550 4367 3217 566 -315 183 C ATOM 799 N PRO X 384 13.043 23.462 61.677 1.00 28.37 N ANISOU 799 N PRO X 384 3361 4395 3021 313 -395 232 N ATOM 800 CA PRO X 384 13.597 22.145 62.003 1.00 28.81 C ANISOU 800 CA PRO X 384 3462 4386 3096 278 -442 263 C ATOM 801 C PRO X 384 14.933 21.851 61.323 1.00 28.91 C ANISOU 801 C PRO X 384 3489 4305 3189 327 -455 206 C ATOM 802 O PRO X 384 15.803 21.219 61.926 1.00 29.56 O ANISOU 802 O PRO X 384 3573 4325 3330 359 -516 214 O ATOM 803 CB PRO X 384 12.524 21.184 61.491 1.00 29.32 C ANISOU 803 CB PRO X 384 3528 4441 3168 198 -458 292 C ATOM 804 CG PRO X 384 11.267 21.946 61.623 1.00 29.49 C ANISOU 804 CG PRO X 384 3456 4576 3170 182 -421 293 C ATOM 805 CD PRO X 384 11.617 23.373 61.315 1.00 28.83 C ANISOU 805 CD PRO X 384 3359 4514 3080 282 -401 250 C ATOM 806 N GLU X 385 15.088 22.314 60.084 1.00 28.86 N ANISOU 806 N GLU X 385 3493 4287 3183 336 -395 149 N ATOM 807 CA GLU X 385 16.315 22.116 59.315 1.00 29.54 C ANISOU 807 CA GLU X 385 3576 4302 3343 362 -333 64 C ATOM 808 C GLU X 385 17.505 22.847 59.940 1.00 29.80 C ANISOU 808 C GLU X 385 3517 4336 3470 396 -312 21 C ATOM 809 O GLU X 385 18.656 22.453 59.741 1.00 30.66 O ANISOU 809 O GLU X 385 3548 4389 3710 429 -282 -59 O ATOM 810 CB GLU X 385 16.108 22.583 57.870 1.00 29.81 C ANISOU 810 CB GLU X 385 3697 4341 3286 330 -246 28 C ATOM 811 CG GLU X 385 17.172 22.105 56.886 1.00 31.21 C ANISOU 811 CG GLU X 385 3899 4454 3502 327 -122 -85 C ATOM 812 CD GLU X 385 16.928 22.580 55.461 1.00 32.35 C ANISOU 812 CD GLU X 385 4202 4616 3474 269 -27 -103 C ATOM 813 OE1 GLU X 385 15.752 22.694 55.047 1.00 32.30 O ANISOU 813 OE1 GLU X 385 4293 4649 3328 246 -134 -38 O ATOM 814 OE2 GLU X 385 17.923 22.832 54.748 1.00 33.70 O ANISOU 814 OE2 GLU X 385 4397 4761 3643 240 153 -185 O ATOM 815 N LEU X 386 17.216 23.901 60.702 1.00 29.61 N ANISOU 815 N LEU X 386 3481 4368 3399 388 -331 51 N ATOM 816 CA LEU X 386 18.248 24.762 61.281 1.00 30.20 C ANISOU 816 CA LEU X 386 3475 4442 3556 389 -328 -11 C ATOM 817 C LEU X 386 18.435 24.567 62.789 1.00 30.79 C ANISOU 817 C LEU X 386 3525 4555 3618 411 -477 3 C ATOM 818 O LEU X 386 19.050 25.404 63.454 1.00 31.35 O ANISOU 818 O LEU X 386 3547 4643 3719 396 -515 -59 O ATOM 819 CB LEU X 386 17.936 26.237 60.980 1.00 29.99 C ANISOU 819 CB LEU X 386 3493 4412 3488 353 -241 -17 C ATOM 820 CG LEU X 386 17.738 26.703 59.532 1.00 30.08 C ANISOU 820 CG LEU X 386 3597 4376 3455 321 -117 5 C ATOM 821 CD1 LEU X 386 17.383 28.182 59.505 1.00 30.24 C ANISOU 821 CD1 LEU X 386 3688 4347 3453 308 -78 30 C ATOM 822 CD2 LEU X 386 18.967 26.434 58.667 1.00 31.10 C ANISOU 822 CD2 LEU X 386 3684 4462 3668 272 15 -70 C ATOM 823 N CYS X 387 17.910 23.466 63.324 1.00 31.19 N ANISOU 823 N CYS X 387 3636 4609 3605 428 -566 88 N ATOM 824 CA CYS X 387 17.992 23.196 64.761 1.00 32.47 C ANISOU 824 CA CYS X 387 3849 4805 3681 433 -710 139 C ATOM 825 C CYS X 387 18.564 21.817 65.064 1.00 33.87 C ANISOU 825 C CYS X 387 4046 4895 3926 489 -861 206 C ATOM 826 O CYS X 387 18.132 20.819 64.488 1.00 33.89 O ANISOU 826 O CYS X 387 4095 4819 3962 489 -831 259 O ATOM 827 CB CYS X 387 16.617 23.332 65.417 1.00 32.22 C ANISOU 827 CB CYS X 387 3927 4854 3460 374 -652 210 C ATOM 828 SG CYS X 387 15.878 24.970 65.296 1.00 32.13 S ANISOU 828 SG CYS X 387 3890 4912 3406 359 -509 122 S ATOM 829 N TYR X 388 19.536 21.776 65.972 1.00 35.60 N ANISOU 829 N TYR X 388 4236 5111 4177 540 -1050 198 N ATOM 830 CA TYR X 388 20.094 20.525 66.468 1.00 37.65 C ANISOU 830 CA TYR X 388 4539 5264 4502 626 -1257 290 C ATOM 831 C TYR X 388 19.274 20.007 67.640 1.00 38.88 C ANISOU 831 C TYR X 388 4941 5436 4396 565 -1345 467 C ATOM 832 O TYR X 388 18.539 20.762 68.273 1.00 38.63 O ANISOU 832 O TYR X 388 5004 5532 4142 469 -1261 473 O ATOM 833 CB TYR X 388 21.542 20.717 66.919 1.00 39.51 C ANISOU 833 CB TYR X 388 4612 5492 4907 724 -1475 204 C ATOM 834 CG TYR X 388 22.521 21.071 65.822 1.00 39.34 C ANISOU 834 CG TYR X 388 4317 5445 5185 769 -1363 23 C ATOM 835 CD1 TYR X 388 22.537 20.373 64.613 1.00 38.59 C ANISOU 835 CD1 TYR X 388 4164 5249 5247 812 -1199 -20 C ATOM 836 CD2 TYR X 388 23.460 22.084 66.011 1.00 40.15 C ANISOU 836 CD2 TYR X 388 4226 5620 5408 747 -1406 -119 C ATOM 837 CE1 TYR X 388 23.444 20.693 63.613 1.00 39.09 C ANISOU 837 CE1 TYR X 388 3997 5303 5551 831 -1041 -197 C ATOM 838 CE2 TYR X 388 24.377 22.406 65.020 1.00 40.62 C ANISOU 838 CE2 TYR X 388 4026 5659 5748 751 -1254 -285 C ATOM 839 CZ TYR X 388 24.362 21.709 63.824 1.00 40.14 C ANISOU 839 CZ TYR X 388 3925 5513 5810 794 -1055 -320 C ATOM 840 OH TYR X 388 25.267 22.031 62.841 1.00 41.22 O ANISOU 840 OH TYR X 388 3826 5643 6191 776 -850 -494 O ATOM 841 N LEU X 389 19.421 18.719 67.934 1.00 40.91 N ANISOU 841 N LEU X 389 5314 5545 4683 619 -1496 606 N ATOM 842 CA LEU X 389 18.695 18.083 69.030 1.00 42.85 C ANISOU 842 CA LEU X 389 5841 5773 4666 533 -1563 811 C ATOM 843 C LEU X 389 19.488 18.075 70.333 1.00 45.81 C ANISOU 843 C LEU X 389 6346 6163 4893 590 -1867 897 C ATOM 844 O LEU X 389 20.715 18.209 70.331 1.00 46.90 O ANISOU 844 O LEU X 389 6321 6275 5223 733 -2092 812 O ATOM 845 CB LEU X 389 18.318 16.649 68.653 1.00 43.76 C ANISOU 845 CB LEU X 389 6074 5675 4878 530 -1564 947 C ATOM 846 CG LEU X 389 17.232 16.456 67.597 1.00 41.93 C ANISOU 846 CG LEU X 389 5795 5431 4703 417 -1300 898 C ATOM 847 CD1 LEU X 389 17.498 15.173 66.843 1.00 43.07 C ANISOU 847 CD1 LEU X 389 5957 5324 5082 486 -1353 913 C ATOM 848 CD2 LEU X 389 15.840 16.451 68.225 1.00 42.24 C ANISOU 848 CD2 LEU X 389 5994 5561 4493 214 -1135 1015 C ATOM 849 N THR X 390 18.768 17.922 71.442 1.00 47.68 N ANISOU 849 N THR X 390 6877 6455 4784 466 -1868 1059 N ATOM 850 CA THR X 390 19.360 17.786 72.772 1.00 51.23 C ANISOU 850 CA THR X 390 7556 6920 4990 493 -2178 1184 C ATOM 851 C THR X 390 18.418 16.957 73.647 1.00 53.68 C ANISOU 851 C THR X 390 8256 7179 4960 339 -2119 1446 C ATOM 852 O THR X 390 17.193 17.058 73.515 1.00 52.63 O ANISOU 852 O THR X 390 8171 7118 4706 164 -1778 1452 O ATOM 853 CB THR X 390 19.591 19.166 73.446 1.00 51.22 C ANISOU 853 CB THR X 390 7526 7144 4789 447 -2200 1014 C ATOM 854 OG1 THR X 390 20.212 20.069 72.523 1.00 48.84 O ANISOU 854 OG1 THR X 390 6869 6887 4801 521 -2145 768 O ATOM 855 CG2 THR X 390 20.471 19.031 74.679 1.00 55.27 C ANISOU 855 CG2 THR X 390 8238 7672 5089 503 -2613 1103 C ATOM 856 N GLY X 391 18.985 16.133 74.526 1.00 57.44 N ANISOU 856 N GLY X 391 9005 7524 5295 399 -2451 1668 N ATOM 857 CA GLY X 391 18.199 15.467 75.562 1.00 60.72 C ANISOU 857 CA GLY X 391 9866 7902 5300 220 -2405 1943 C ATOM 858 C GLY X 391 17.847 16.495 76.620 1.00 61.95 C ANISOU 858 C GLY X 391 10200 8333 5004 75 -2313 1874 C ATOM 859 O GLY X 391 18.744 17.077 77.235 1.00 63.51 O ANISOU 859 O GLY X 391 10419 8627 5084 170 -2618 1798 O ATOM 860 N LEU X 392 16.549 16.735 76.825 1.00 61.69 N ANISOU 860 N LEU X 392 10272 8427 4738 -154 -1891 1870 N ATOM 861 CA LEU X 392 16.102 17.804 77.729 1.00 62.79 C ANISOU 861 CA LEU X 392 10544 8834 4479 -288 -1714 1736 C ATOM 862 C LEU X 392 14.683 17.664 78.299 1.00 64.48 C ANISOU 862 C LEU X 392 10985 9149 4362 -561 -1270 1818 C ATOM 863 O LEU X 392 13.890 16.839 77.839 1.00 64.22 O ANISOU 863 O LEU X 392 10935 8997 4466 -676 -1048 1952 O ATOM 864 CB LEU X 392 16.238 19.157 77.032 1.00 59.23 C ANISOU 864 CB LEU X 392 9697 8534 4272 -200 -1597 1387 C ATOM 865 N THR X 393 14.388 18.485 79.308 1.00 66.64 N ANISOU 865 N THR X 393 11460 9646 4213 -676 -1131 1709 N ATOM 866 CA THR X 393 13.062 18.558 79.923 1.00 68.79 C ANISOU 866 CA THR X 393 11905 10065 4166 -937 -645 1715 C ATOM 867 C THR X 393 12.281 19.739 79.350 1.00 65.86 C ANISOU 867 C THR X 393 11138 9869 4014 -927 -268 1369 C ATOM 868 O THR X 393 12.778 20.866 79.311 1.00 64.49 O ANISOU 868 O THR X 393 10817 9795 3888 -796 -361 1110 O ATOM 869 CB THR X 393 13.150 18.704 81.466 1.00 73.89 C ANISOU 869 CB THR X 393 13071 10851 4150 -1083 -676 1793 C ATOM 870 OG1 THR X 393 13.919 17.626 82.014 1.00 77.25 O ANISOU 870 OG1 THR X 393 13895 11092 4362 -1065 -1096 2146 O ATOM 871 CG2 THR X 393 11.758 18.698 82.099 1.00 76.71 C ANISOU 871 CG2 THR X 393 13602 11362 4179 -1379 -99 1793 C TER 872 THR X 393 ATOM 873 O5' G A 1 29.320 31.088 42.580 1.00 47.99 O ANISOU 873 O5' G A 1 5939 6280 6014 -531 426 -476 O ATOM 874 C5' G A 1 28.155 30.348 42.928 1.00 48.04 C ANISOU 874 C5' G A 1 5978 6385 5887 -647 399 -534 C ATOM 875 C4' G A 1 28.511 28.967 43.453 1.00 48.12 C ANISOU 875 C4' G A 1 6117 6246 5918 -748 362 -639 C ATOM 876 O4' G A 1 29.522 28.352 42.614 1.00 48.64 O ANISOU 876 O4' G A 1 6207 6246 6028 -732 386 -684 O ATOM 877 C3' G A 1 29.119 28.931 44.849 1.00 47.34 C ANISOU 877 C3' G A 1 6112 5939 5932 -727 308 -631 C ATOM 878 O3' G A 1 28.098 29.010 45.839 1.00 46.42 O ANISOU 878 O3' G A 1 6023 5856 5758 -778 285 -621 O ATOM 879 C2' G A 1 29.819 27.575 44.833 1.00 48.01 C ANISOU 879 C2' G A 1 6305 5888 6047 -776 310 -708 C ATOM 880 O2' G A 1 28.942 26.484 45.049 1.00 48.65 O ANISOU 880 O2' G A 1 6458 5987 6039 -902 331 -779 O ATOM 881 C1' G A 1 30.363 27.529 43.406 1.00 48.72 C ANISOU 881 C1' G A 1 6336 6040 6133 -747 358 -725 C ATOM 882 N9 G A 1 31.752 27.984 43.275 1.00 48.98 N ANISOU 882 N9 G A 1 6353 5951 6305 -635 352 -683 N ATOM 883 C8 G A 1 32.196 29.117 42.634 1.00 49.06 C ANISOU 883 C8 G A 1 6257 6009 6373 -536 380 -612 C ATOM 884 N7 G A 1 33.491 29.270 42.674 1.00 49.13 N ANISOU 884 N7 G A 1 6266 5879 6520 -461 376 -598 N ATOM 885 C5 G A 1 33.944 28.167 43.385 1.00 49.03 C ANISOU 885 C5 G A 1 6364 5733 6531 -499 335 -655 C ATOM 886 C6 G A 1 35.262 27.789 43.746 1.00 49.06 C ANISOU 886 C6 G A 1 6405 5581 6654 -439 311 -661 C ATOM 887 O6 G A 1 36.321 28.381 43.495 1.00 48.95 O ANISOU 887 O6 G A 1 6324 5514 6759 -356 316 -632 O ATOM 888 N1 G A 1 35.287 26.594 44.470 1.00 49.30 N ANISOU 888 N1 G A 1 6555 5517 6658 -479 291 -700 N ATOM 889 C2 G A 1 34.172 25.858 44.802 1.00 49.52 C ANISOU 889 C2 G A 1 6662 5576 6575 -579 304 -737 C ATOM 890 N2 G A 1 34.375 24.734 45.501 1.00 49.91 N ANISOU 890 N2 G A 1 6831 5502 6627 -593 312 -756 N ATOM 891 N3 G A 1 32.933 26.202 44.468 1.00 49.67 N ANISOU 891 N3 G A 1 6640 5743 6490 -654 321 -748 N ATOM 892 C4 G A 1 32.887 27.364 43.762 1.00 49.25 C ANISOU 892 C4 G A 1 6466 5803 6444 -603 330 -702 C ATOM 893 P C A 2 28.287 29.902 47.157 1.00 45.33 P ANISOU 893 P C A 2 5902 5622 5698 -710 239 -568 P ATOM 894 OP1 C A 2 26.941 30.173 47.712 1.00 45.55 O ANISOU 894 OP1 C A 2 5917 5759 5628 -755 243 -543 O ATOM 895 OP2 C A 2 29.186 31.038 46.852 1.00 45.18 O ANISOU 895 OP2 C A 2 5808 5563 5795 -602 251 -521 O ATOM 896 O5' C A 2 29.070 28.919 48.143 1.00 45.19 O ANISOU 896 O5' C A 2 6010 5424 5734 -718 190 -613 O ATOM 897 C5' C A 2 28.458 27.728 48.629 1.00 45.06 C ANISOU 897 C5' C A 2 6093 5378 5646 -808 200 -651 C ATOM 898 C4' C A 2 29.511 26.745 49.103 1.00 45.11 C ANISOU 898 C4' C A 2 6206 5214 5718 -778 187 -673 C ATOM 899 O4' C A 2 30.459 26.490 48.036 1.00 45.16 O ANISOU 899 O4' C A 2 6189 5187 5783 -751 212 -697 O ATOM 900 C3' C A 2 30.395 27.241 50.236 1.00 44.81 C ANISOU 900 C3' C A 2 6185 5087 5752 -671 114 -640 C ATOM 901 O3' C A 2 29.760 27.107 51.493 1.00 44.92 O ANISOU 901 O3' C A 2 6265 5091 5710 -677 91 -620 O ATOM 902 C2' C A 2 31.605 26.321 50.107 1.00 45.17 C ANISOU 902 C2' C A 2 6291 5008 5864 -622 118 -654 C ATOM 903 O2' C A 2 31.396 25.035 50.658 1.00 46.01 O ANISOU 903 O2' C A 2 6524 5026 5928 -651 158 -654 O ATOM 904 C1' C A 2 31.744 26.241 48.590 1.00 45.16 C ANISOU 904 C1' C A 2 6234 5047 5876 -660 175 -684 C ATOM 905 N1 C A 2 32.776 27.181 48.015 1.00 44.70 N ANISOU 905 N1 C A 2 6074 4991 5917 -574 152 -668 N ATOM 906 C2 C A 2 34.141 26.835 48.063 1.00 44.95 C ANISOU 906 C2 C A 2 6120 4915 6044 -494 133 -669 C ATOM 907 O2 C A 2 34.496 25.766 48.576 1.00 45.34 O ANISOU 907 O2 C A 2 6268 4871 6086 -479 137 -671 O ATOM 908 N3 C A 2 35.053 27.696 47.539 1.00 44.85 N ANISOU 908 N3 C A 2 6005 4901 6133 -427 124 -659 N ATOM 909 C4 C A 2 34.659 28.848 46.987 1.00 44.51 C ANISOU 909 C4 C A 2 5863 4944 6105 -430 148 -640 C ATOM 910 N4 C A 2 35.601 29.653 46.487 1.00 44.59 N ANISOU 910 N4 C A 2 5778 4929 6235 -364 162 -626 N ATOM 911 C5 C A 2 33.281 29.221 46.925 1.00 44.21 C ANISOU 911 C5 C A 2 5813 5020 5965 -492 171 -625 C ATOM 912 C6 C A 2 32.390 28.367 47.445 1.00 44.32 C ANISOU 912 C6 C A 2 5917 5049 5874 -566 165 -644 C ATOM 913 P G A 3 30.057 28.193 52.627 1.00 44.85 P ANISOU 913 P G A 3 6223 5089 5728 -591 12 -602 P ATOM 914 OP1 G A 3 29.896 27.522 53.940 1.00 45.34 O ANISOU 914 OP1 G A 3 6390 5105 5731 -565 -11 -582 O ATOM 915 OP2 G A 3 29.254 29.393 52.302 1.00 44.64 O ANISOU 915 OP2 G A 3 6105 5168 5689 -614 29 -588 O ATOM 916 O5' G A 3 31.593 28.580 52.381 1.00 44.37 O ANISOU 916 O5' G A 3 6104 4968 5785 -503 -31 -623 O ATOM 917 C5' G A 3 32.510 28.721 53.453 1.00 43.86 C ANISOU 917 C5' G A 3 6045 4864 5755 -414 -110 -636 C ATOM 918 C4' G A 3 33.640 27.713 53.353 1.00 43.69 C ANISOU 918 C4' G A 3 6065 4762 5770 -354 -119 -632 C ATOM 919 O4' G A 3 33.980 27.428 51.973 1.00 43.18 O ANISOU 919 O4' G A 3 5973 4668 5763 -385 -58 -637 O ATOM 920 C3' G A 3 34.942 28.202 53.962 1.00 43.89 C ANISOU 920 C3' G A 3 6021 4785 5868 -254 -205 -662 C ATOM 921 O3' G A 3 34.926 27.961 55.354 1.00 44.61 O ANISOU 921 O3' G A 3 6164 4905 5879 -191 -268 -654 O ATOM 922 C2' G A 3 35.986 27.371 53.221 1.00 44.05 C ANISOU 922 C2' G A 3 6048 4736 5951 -210 -180 -649 C ATOM 923 O2' G A 3 36.136 26.052 53.714 1.00 44.58 O ANISOU 923 O2' G A 3 6232 4749 5957 -157 -159 -599 O ATOM 924 C1' G A 3 35.388 27.370 51.814 1.00 43.20 C ANISOU 924 C1' G A 3 5932 4621 5860 -301 -89 -647 C ATOM 925 N9 G A 3 35.811 28.506 50.989 1.00 42.26 N ANISOU 925 N9 G A 3 5685 4527 5841 -303 -82 -671 N ATOM 926 C8 G A 3 34.994 29.454 50.420 1.00 41.57 C ANISOU 926 C8 G A 3 5538 4502 5753 -358 -40 -668 C ATOM 927 N7 G A 3 35.632 30.360 49.735 1.00 41.32 N ANISOU 927 N7 G A 3 5400 4466 5833 -331 -16 -675 N ATOM 928 C5 G A 3 36.964 29.993 49.852 1.00 41.63 C ANISOU 928 C5 G A 3 5419 4442 5955 -268 -55 -697 C ATOM 929 C6 G A 3 38.125 30.604 49.316 1.00 41.71 C ANISOU 929 C6 G A 3 5321 4417 6109 -222 -43 -715 C ATOM 930 O6 G A 3 38.195 31.620 48.611 1.00 41.27 O ANISOU 930 O6 G A 3 5173 4364 6143 -227 17 -709 O ATOM 931 N1 G A 3 39.288 29.919 49.672 1.00 42.42 N ANISOU 931 N1 G A 3 5412 4466 6240 -157 -96 -731 N ATOM 932 C2 G A 3 39.320 28.782 50.450 1.00 42.86 C ANISOU 932 C2 G A 3 5569 4512 6203 -123 -144 -715 C ATOM 933 N2 G A 3 40.527 28.253 50.694 1.00 43.55 N ANISOU 933 N2 G A 3 5634 4575 6337 -37 -183 -715 N ATOM 934 N3 G A 3 38.237 28.201 50.956 1.00 42.63 N ANISOU 934 N3 G A 3 5653 4498 6047 -162 -139 -691 N ATOM 935 C4 G A 3 37.095 28.855 50.621 1.00 42.13 C ANISOU 935 C4 G A 3 5582 4478 5945 -242 -99 -690 C ATOM 936 P A A 4 35.367 29.130 56.348 1.00 44.92 P ANISOU 936 P A A 4 6109 5021 5936 -144 -366 -724 P ATOM 937 OP1 A A 4 34.852 28.809 57.698 1.00 45.79 O ANISOU 937 OP1 A A 4 6299 5184 5915 -98 -408 -702 O ATOM 938 OP2 A A 4 35.031 30.433 55.726 1.00 44.42 O ANISOU 938 OP2 A A 4 5951 4967 5957 -217 -335 -771 O ATOM 939 O5' A A 4 36.954 28.960 56.351 1.00 45.37 O ANISOU 939 O5' A A 4 6090 5078 6071 -52 -428 -755 O ATOM 940 C5' A A 4 37.536 27.721 56.747 1.00 45.65 C ANISOU 940 C5' A A 4 6196 5099 6048 47 -441 -692 C ATOM 941 C4' A A 4 39.014 27.704 56.419 1.00 45.90 C ANISOU 941 C4' A A 4 6126 5135 6176 122 -483 -719 C ATOM 942 O4' A A 4 39.201 27.776 54.984 1.00 44.89 O ANISOU 942 O4' A A 4 5967 4923 6164 58 -404 -717 O ATOM 943 C3' A A 4 39.794 28.894 56.949 1.00 46.31 C ANISOU 943 C3' A A 4 6019 5283 6292 136 -582 -834 C ATOM 944 O3' A A 4 40.101 28.707 58.329 1.00 47.76 O ANISOU 944 O3' A A 4 6197 5588 6360 238 -682 -849 O ATOM 945 C2' A A 4 41.013 28.876 56.031 1.00 46.23 C ANISOU 945 C2' A A 4 5909 5235 6420 161 -571 -849 C ATOM 946 O2' A A 4 41.974 27.899 56.385 1.00 47.26 O ANISOU 946 O2' A A 4 6044 5398 6511 293 -609 -797 O ATOM 947 C1' A A 4 40.365 28.528 54.691 1.00 44.88 C ANISOU 947 C1' A A 4 5816 4945 6290 82 -448 -785 C ATOM 948 N9 A A 4 39.986 29.690 53.880 1.00 43.83 N ANISOU 948 N9 A A 4 5607 4786 6257 -17 -397 -833 N ATOM 949 C8 A A 4 38.718 30.098 53.563 1.00 42.76 C ANISOU 949 C8 A A 4 5521 4640 6084 -104 -336 -815 C ATOM 950 N7 A A 4 38.672 31.175 52.816 1.00 42.24 N ANISOU 950 N7 A A 4 5365 4556 6125 -155 -283 -844 N ATOM 951 C5 A A 4 40.004 31.504 52.625 1.00 42.85 C ANISOU 951 C5 A A 4 5328 4619 6333 -114 -306 -894 C ATOM 952 C6 A A 4 40.639 32.552 51.919 1.00 43.01 C ANISOU 952 C6 A A 4 5218 4602 6521 -135 -253 -937 C ATOM 953 N6 A A 4 39.974 33.498 51.248 1.00 42.52 N ANISOU 953 N6 A A 4 5128 4510 6516 -189 -156 -922 N ATOM 954 N1 A A 4 41.992 32.594 51.929 1.00 43.87 N ANISOU 954 N1 A A 4 5220 4706 6739 -91 -291 -989 N ATOM 955 C2 A A 4 42.664 31.650 52.601 1.00 44.58 C ANISOU 955 C2 A A 4 5330 4846 6762 -14 -383 -987 C ATOM 956 N3 A A 4 42.177 30.621 53.297 1.00 44.66 N ANISOU 956 N3 A A 4 5465 4891 6611 29 -431 -933 N ATOM 957 C4 A A 4 40.830 30.600 53.273 1.00 43.78 C ANISOU 957 C4 A A 4 5462 4765 6407 -31 -385 -892 C ATOM 958 P A A 5 39.922 29.903 59.384 1.00 48.36 P ANISOU 958 P A A 5 6187 5782 6402 211 -771 -977 P ATOM 959 OP1 A A 5 39.827 29.301 60.732 1.00 49.60 O ANISOU 959 OP1 A A 5 6404 6060 6379 329 -844 -942 O ATOM 960 OP2 A A 5 38.853 30.813 58.916 1.00 47.06 O ANISOU 960 OP2 A A 5 6040 5548 6292 79 -699 -1008 O ATOM 961 O5' A A 5 41.311 30.688 59.264 1.00 49.88 O ANISOU 961 O5' A A 5 6185 6037 6729 217 -841 -1109 O ATOM 962 C5' A A 5 42.555 29.986 59.317 1.00 51.58 C ANISOU 962 C5' A A 5 6334 6316 6946 334 -897 -1085 C ATOM 963 C4' A A 5 43.678 30.781 58.671 1.00 52.42 C ANISOU 963 C4' A A 5 6257 6420 7237 289 -910 -1197 C ATOM 964 O4' A A 5 43.503 30.861 57.234 1.00 51.11 O ANISOU 964 O4' A A 5 6118 6085 7214 209 -787 -1143 O ATOM 965 C3' A A 5 43.777 32.235 59.101 1.00 53.23 C ANISOU 965 C3' A A 5 6221 6577 7425 189 -949 -1385 C ATOM 966 O3' A A 5 44.399 32.325 60.373 1.00 55.68 O ANISOU 966 O3' A A 5 6432 7091 7631 262 -1087 -1492 O ATOM 967 C2' A A 5 44.617 32.821 57.970 1.00 53.02 C ANISOU 967 C2' A A 5 6066 6458 7622 124 -885 -1435 C ATOM 968 O2' A A 5 46.003 32.557 58.088 1.00 54.40 O ANISOU 968 O2' A A 5 6095 6734 7838 200 -962 -1482 O ATOM 969 C1' A A 5 44.033 32.090 56.763 1.00 51.36 C ANISOU 969 C1' A A 5 5996 6091 7427 120 -766 -1267 C ATOM 970 N9 A A 5 42.977 32.851 56.091 1.00 50.19 N ANISOU 970 N9 A A 5 5901 5827 7342 7 -656 -1257 N ATOM 971 C8 A A 5 41.625 32.690 56.230 1.00 49.30 C ANISOU 971 C8 A A 5 5930 5686 7114 -24 -616 -1187 C ATOM 972 N7 A A 5 40.910 33.517 55.505 1.00 48.46 N ANISOU 972 N7 A A 5 5826 5496 7090 -111 -513 -1182 N ATOM 973 C5 A A 5 41.856 34.278 54.842 1.00 48.78 C ANISOU 973 C5 A A 5 5727 5489 7319 -138 -471 -1249 C ATOM 974 C6 A A 5 41.747 35.336 53.913 1.00 48.45 C ANISOU 974 C6 A A 5 5619 5348 7439 -204 -344 -1259 C ATOM 975 N6 A A 5 40.576 35.821 53.486 1.00 47.60 N ANISOU 975 N6 A A 5 5578 5193 7313 -248 -246 -1196 N ATOM 976 N1 A A 5 42.891 35.884 53.441 1.00 49.19 N ANISOU 976 N1 A A 5 5570 5401 7715 -214 -312 -1326 N ATOM 977 C2 A A 5 44.066 35.402 53.871 1.00 50.10 C ANISOU 977 C2 A A 5 5602 5588 7844 -165 -414 -1388 C ATOM 978 N3 A A 5 44.292 34.411 54.736 1.00 50.51 N ANISOU 978 N3 A A 5 5697 5754 7740 -87 -543 -1378 N ATOM 979 C4 A A 5 43.138 33.885 55.192 1.00 49.83 C ANISOU 979 C4 A A 5 5765 5688 7480 -75 -560 -1303 C ATOM 980 P U A 6 43.740 33.197 61.545 1.00 56.82 P ANISOU 980 P U A 6 6566 7338 7682 211 -1145 -1631 P ATOM 981 OP1 U A 6 44.094 32.548 62.827 1.00 58.40 O ANISOU 981 OP1 U A 6 6755 7763 7672 358 -1279 -1632 O ATOM 982 OP2 U A 6 42.322 33.471 61.219 1.00 55.17 O ANISOU 982 OP2 U A 6 6508 6983 7470 125 -1038 -1562 O ATOM 983 O5' U A 6 44.518 34.586 61.442 1.00 58.10 O ANISOU 983 O5' U A 6 6523 7513 8039 89 -1152 -1861 O ATOM 984 C5' U A 6 45.925 34.612 61.249 1.00 60.08 C ANISOU 984 C5' U A 6 6589 7847 8392 112 -1209 -1946 C ATOM 985 C4' U A 6 46.332 35.859 60.489 1.00 60.61 C ANISOU 985 C4' U A 6 6521 7786 8722 -41 -1115 -2091 C ATOM 986 O4' U A 6 45.976 35.742 59.089 1.00 58.89 O ANISOU 986 O4' U A 6 6391 7346 8638 -75 -966 -1938 O ATOM 987 C3' U A 6 45.624 37.136 60.912 1.00 61.05 C ANISOU 987 C3' U A 6 6568 7789 8838 -175 -1061 -2249 C ATOM 988 O3' U A 6 46.146 37.628 62.138 1.00 63.57 O ANISOU 988 O3' U A 6 6749 8314 9090 -190 -1185 -2473 O ATOM 989 C2' U A 6 45.930 38.035 59.719 1.00 60.69 C ANISOU 989 C2' U A 6 6443 7542 9074 -292 -903 -2284 C ATOM 990 O2' U A 6 47.231 38.593 59.752 1.00 62.59 O ANISOU 990 O2' U A 6 6461 7844 9474 -347 -932 -2470 O ATOM 991 C1' U A 6 45.786 37.046 58.560 1.00 58.98 C ANISOU 991 C1' U A 6 6341 7214 8854 -216 -840 -2041 C ATOM 992 N1 U A 6 44.453 37.165 57.867 1.00 57.19 N ANISOU 992 N1 U A 6 6284 6822 8622 -250 -706 -1897 N ATOM 993 C2 U A 6 44.308 38.094 56.848 1.00 56.84 C ANISOU 993 C2 U A 6 6208 6605 8782 -336 -541 -1892 C ATOM 994 O2 U A 6 45.201 38.828 56.461 1.00 57.98 O ANISOU 994 O2 U A 6 6202 6697 9130 -394 -483 -1999 O ATOM 995 N3 U A 6 43.057 38.138 56.279 1.00 55.47 N ANISOU 995 N3 U A 6 6179 6329 8568 -346 -434 -1751 N ATOM 996 C4 U A 6 41.958 37.367 56.618 1.00 54.51 C ANISOU 996 C4 U A 6 6220 6250 8238 -300 -474 -1633 C ATOM 997 O4 U A 6 40.902 37.524 56.013 1.00 53.57 O ANISOU 997 O4 U A 6 6197 6051 8105 -320 -369 -1523 O ATOM 998 C5 U A 6 42.179 36.424 57.688 1.00 54.87 C ANISOU 998 C5 U A 6 6300 6448 8098 -222 -632 -1646 C ATOM 999 C6 U A 6 43.390 36.363 58.259 1.00 56.25 C ANISOU 999 C6 U A 6 6341 6736 8295 -191 -740 -1767 C ATOM 1000 P A A 7 45.167 38.302 63.213 1.00 64.31 P ANISOU 1000 P A A 7 6909 8458 9067 -241 -1199 -2591 P ATOM 1001 OP1 A A 7 45.958 38.529 64.443 1.00 66.86 O ANISOU 1001 OP1 A A 7 7068 9051 9285 -226 -1358 -2820 O ATOM 1002 OP2 A A 7 43.916 37.513 63.292 1.00 62.30 O ANISOU 1002 OP2 A A 7 6883 8156 8631 -158 -1178 -2371 O ATOM 1003 O5' A A 7 44.832 39.716 62.537 1.00 64.24 O ANISOU 1003 O5' A A 7 6869 8218 9321 -417 -1017 -2702 O ATOM 1004 C5' A A 7 45.875 40.673 62.334 1.00 66.09 C ANISOU 1004 C5' A A 7 6896 8429 9787 -535 -977 -2922 C ATOM 1005 C4' A A 7 45.465 41.788 61.389 1.00 65.57 C ANISOU 1005 C4' A A 7 6843 8085 9983 -664 -750 -2930 C ATOM 1006 O4' A A 7 45.111 41.267 60.084 1.00 63.54 O ANISOU 1006 O4' A A 7 6697 7662 9783 -610 -643 -2668 O ATOM 1007 C3' A A 7 44.229 42.571 61.796 1.00 65.39 C ANISOU 1007 C3' A A 7 6942 7965 9937 -722 -649 -2957 C ATOM 1008 O3' A A 7 44.542 43.497 62.829 1.00 67.88 O ANISOU 1008 O3' A A 7 7139 8366 10285 -824 -677 -3256 O ATOM 1009 C2' A A 7 43.863 43.250 60.478 1.00 64.29 C ANISOU 1009 C2' A A 7 6840 7552 10035 -778 -415 -2839 C ATOM 1010 O2' A A 7 44.630 44.410 60.208 1.00 65.81 O ANISOU 1010 O2' A A 7 6872 7624 10509 -908 -283 -3035 O ATOM 1011 C1' A A 7 44.177 42.144 59.471 1.00 62.78 C ANISOU 1011 C1' A A 7 6685 7352 9814 -678 -445 -2610 C ATOM 1012 N9 A A 7 42.986 41.397 59.055 1.00 60.64 N ANISOU 1012 N9 A A 7 6614 7043 9384 -592 -423 -2358 N ATOM 1013 C8 A A 7 42.562 40.183 59.523 1.00 59.87 C ANISOU 1013 C8 A A 7 6632 7079 9036 -488 -561 -2234 C ATOM 1014 N7 A A 7 41.454 39.751 58.968 1.00 58.15 N ANISOU 1014 N7 A A 7 6572 6785 8735 -450 -493 -2033 N ATOM 1015 C5 A A 7 41.122 40.752 58.071 1.00 57.76 C ANISOU 1015 C5 A A 7 6506 6561 8876 -517 -305 -2011 C ATOM 1016 C6 A A 7 40.049 40.906 57.162 1.00 56.32 C ANISOU 1016 C6 A A 7 6428 6265 8704 -509 -161 -1834 C ATOM 1017 N6 A A 7 39.075 40.002 57.015 1.00 54.88 N ANISOU 1017 N6 A A 7 6387 6126 8337 -451 -192 -1664 N ATOM 1018 N1 A A 7 40.010 42.029 56.409 1.00 56.59 N ANISOU 1018 N1 A A 7 6408 6146 8945 -558 26 -1838 N ATOM 1019 C2 A A 7 40.984 42.940 56.555 1.00 58.16 C ANISOU 1019 C2 A A 7 6464 6283 9351 -632 79 -2020 C ATOM 1020 N3 A A 7 42.041 42.904 57.373 1.00 59.58 N ANISOU 1020 N3 A A 7 6525 6559 9552 -670 -49 -2221 N ATOM 1021 C4 A A 7 42.055 41.777 58.111 1.00 59.25 C ANISOU 1021 C4 A A 7 6536 6697 9280 -601 -248 -2201 C ATOM 1022 P U A 8 43.451 43.850 63.947 1.00 68.53 P ANISOU 1022 P U A 8 7336 8507 10192 -830 -696 -3329 P ATOM 1023 OP1 U A 8 44.123 44.663 64.987 1.00 71.14 O ANISOU 1023 OP1 U A 8 7502 8972 10553 -936 -755 -3677 O ATOM 1024 OP2 U A 8 42.751 42.604 64.337 1.00 67.19 O ANISOU 1024 OP2 U A 8 7326 8472 9730 -675 -828 -3113 O ATOM 1025 O5' U A 8 42.407 44.763 63.145 1.00 67.30 O ANISOU 1025 O5' U A 8 7296 8059 10214 -895 -442 -3226 O ATOM 1026 C5' U A 8 42.802 46.045 62.655 1.00 68.55 C ANISOU 1026 C5' U A 8 7349 8018 10679 -1033 -243 -3380 C ATOM 1027 C4' U A 8 41.763 46.641 61.720 1.00 66.99 C ANISOU 1027 C4' U A 8 7280 7562 10610 -1032 -1 -3187 C ATOM 1028 O4' U A 8 41.588 45.799 60.554 1.00 64.98 O ANISOU 1028 O4' U A 8 7097 7259 10331 -931 13 -2895 O ATOM 1029 C3' U A 8 40.357 46.763 62.290 1.00 66.02 C ANISOU 1029 C3' U A 8 7326 7436 10322 -991 30 -3107 C ATOM 1030 O3' U A 8 40.263 47.891 63.155 1.00 67.40 O ANISOU 1030 O3' U A 8 7462 7569 10578 -1098 113 -3365 O ATOM 1031 C2' U A 8 39.534 46.908 61.011 1.00 64.37 C ANISOU 1031 C2' U A 8 7220 7030 10208 -940 227 -2831 C ATOM 1032 O2' U A 8 39.547 48.221 60.477 1.00 65.35 O ANISOU 1032 O2' U A 8 7297 6921 10610 -1019 488 -2891 O ATOM 1033 C1' U A 8 40.260 45.941 60.072 1.00 63.43 C ANISOU 1033 C1' U A 8 7059 6948 10092 -880 147 -2683 C ATOM 1034 N1 U A 8 39.600 44.588 59.961 1.00 61.67 N ANISOU 1034 N1 U A 8 6969 6851 9610 -760 8 -2453 N ATOM 1035 C2 U A 8 38.668 44.363 58.957 1.00 60.10 C ANISOU 1035 C2 U A 8 6879 6564 9391 -700 119 -2200 C ATOM 1036 O2 U A 8 38.332 45.198 58.133 1.00 60.21 O ANISOU 1036 O2 U A 8 6890 6415 9569 -714 324 -2127 O ATOM 1037 N3 U A 8 38.125 43.098 58.945 1.00 58.60 N ANISOU 1037 N3 U A 8 6799 6492 8974 -614 -8 -2031 N ATOM 1038 C4 U A 8 38.407 42.056 59.813 1.00 58.63 C ANISOU 1038 C4 U A 8 6826 6668 8779 -568 -213 -2064 C ATOM 1039 O4 U A 8 37.838 40.979 59.673 1.00 57.40 O ANISOU 1039 O4 U A 8 6779 6575 8453 -497 -279 -1896 O ATOM 1040 C5 U A 8 39.384 42.359 60.830 1.00 60.47 C ANISOU 1040 C5 U A 8 6942 7002 9029 -609 -323 -2305 C ATOM 1041 C6 U A 8 39.928 43.584 60.862 1.00 61.90 C ANISOU 1041 C6 U A 8 7003 7090 9425 -709 -218 -2498 C ATOM 1042 P U A 9 39.168 47.961 64.323 1.00 66.93 P ANISOU 1042 P U A 9 7530 7604 10294 -1068 63 -3404 P ATOM 1043 OP1 U A 9 39.696 48.866 65.368 1.00 69.59 O ANISOU 1043 OP1 U A 9 7756 7987 10695 -1194 62 -3765 O ATOM 1044 OP2 U A 9 38.746 46.587 64.690 1.00 65.37 O ANISOU 1044 OP2 U A 9 7434 7614 9789 -934 -147 -3223 O ATOM 1045 O5' U A 9 37.963 48.697 63.574 1.00 65.46 O ANISOU 1045 O5' U A 9 7471 7174 10225 -1052 327 -3212 O ATOM 1046 C5' U A 9 36.624 48.260 63.734 1.00 63.27 C ANISOU 1046 C5' U A 9 7362 6934 9742 -952 318 -3000 C ATOM 1047 C4' U A 9 35.802 48.619 62.511 1.00 61.28 C ANISOU 1047 C4' U A 9 7183 6489 9611 -904 540 -2741 C ATOM 1048 O4' U A 9 36.262 47.850 61.371 1.00 59.82 O ANISOU 1048 O4' U A 9 6967 6305 9454 -854 502 -2559 O ATOM 1049 C3' U A 9 34.323 48.301 62.656 1.00 59.49 C ANISOU 1049 C3' U A 9 7113 6303 9187 -811 556 -2531 C ATOM 1050 O3' U A 9 33.625 49.445 63.138 1.00 59.88 O ANISOU 1050 O3' U A 9 7205 6234 9311 -843 737 -2614 O ATOM 1051 C2' U A 9 33.903 47.912 61.242 1.00 57.80 C ANISOU 1051 C2' U A 9 6931 6024 9006 -735 644 -2239 C ATOM 1052 O2' U A 9 33.548 49.026 60.445 1.00 58.29 O ANISOU 1052 O2' U A 9 6983 5885 9278 -733 916 -2162 O ATOM 1053 C1' U A 9 35.168 47.249 60.698 1.00 57.79 C ANISOU 1053 C1' U A 9 6829 6062 9065 -752 527 -2269 C ATOM 1054 N1 U A 9 35.231 45.740 60.855 1.00 56.52 N ANISOU 1054 N1 U A 9 6713 6092 8669 -688 291 -2171 N ATOM 1055 C2 U A 9 34.399 44.919 60.100 1.00 54.90 C ANISOU 1055 C2 U A 9 6599 5919 8339 -609 288 -1915 C ATOM 1056 O2 U A 9 33.580 45.323 59.290 1.00 54.42 O ANISOU 1056 O2 U A 9 6576 5774 8325 -577 448 -1752 O ATOM 1057 N3 U A 9 34.553 43.569 60.326 1.00 54.04 N ANISOU 1057 N3 U A 9 6532 5958 8042 -563 95 -1855 N ATOM 1058 C4 U A 9 35.434 42.963 61.208 1.00 54.72 C ANISOU 1058 C4 U A 9 6578 6171 8040 -563 -89 -1995 C ATOM 1059 O4 U A 9 35.458 41.741 61.304 1.00 54.07 O ANISOU 1059 O4 U A 9 6549 6199 7796 -502 -224 -1899 O ATOM 1060 C5 U A 9 36.266 43.872 61.955 1.00 56.49 C ANISOU 1060 C5 U A 9 6692 6391 8378 -636 -95 -2254 C ATOM 1061 C6 U A 9 36.135 45.190 61.751 1.00 57.27 C ANISOU 1061 C6 U A 9 6750 6333 8675 -706 91 -2342 C ATOM 1062 P C A 10 32.811 49.376 64.517 1.00 59.96 P ANISOU 1062 P C A 10 7311 6372 9097 -826 648 -2700 P ATOM 1063 OP1 C A 10 32.695 50.755 65.041 1.00 61.67 O ANISOU 1063 OP1 C A 10 7517 6438 9477 -905 844 -2903 O ATOM 1064 OP2 C A 10 33.411 48.322 65.371 1.00 60.07 O ANISOU 1064 OP2 C A 10 7303 6620 8899 -815 367 -2801 O ATOM 1065 O5' C A 10 31.365 48.882 64.037 1.00 57.14 O ANISOU 1065 O5' C A 10 7086 6035 8589 -710 694 -2379 O ATOM 1066 C5' C A 10 31.080 47.493 63.931 1.00 54.18 C ANISOU 1066 C5' C A 10 6765 5827 7992 -638 505 -2204 C ATOM 1067 C4' C A 10 30.207 47.203 62.727 1.00 51.47 C ANISOU 1067 C4' C A 10 6468 5442 7644 -566 608 -1910 C ATOM 1068 O4' C A 10 30.966 46.483 61.721 1.00 50.28 O ANISOU 1068 O4' C A 10 6259 5304 7542 -560 541 -1825 O ATOM 1069 C3' C A 10 29.028 46.305 63.051 1.00 49.67 C ANISOU 1069 C3' C A 10 6349 5352 7168 -497 521 -1738 C ATOM 1070 O3' C A 10 27.913 47.094 63.428 1.00 49.26 O ANISOU 1070 O3' C A 10 6360 5256 7099 -471 668 -1698 O ATOM 1071 C2' C A 10 28.812 45.549 61.744 1.00 48.16 C ANISOU 1071 C2' C A 10 6153 5180 6964 -455 525 -1510 C ATOM 1072 O2' C A 10 28.078 46.287 60.786 1.00 48.26 O ANISOU 1072 O2' C A 10 6156 5104 7077 -416 731 -1353 O ATOM 1073 C1' C A 10 30.253 45.341 61.279 1.00 48.19 C ANISOU 1073 C1' C A 10 6062 5149 7097 -497 456 -1611 C ATOM 1074 N1 C A 10 30.910 44.079 61.805 1.00 47.46 N ANISOU 1074 N1 C A 10 5979 5195 6856 -493 226 -1660 N ATOM 1075 C2 C A 10 30.452 42.806 61.403 1.00 45.94 C ANISOU 1075 C2 C A 10 5851 5096 6508 -447 137 -1484 C ATOM 1076 O2 C A 10 29.507 42.699 60.611 1.00 44.82 O ANISOU 1076 O2 C A 10 5744 4945 6338 -422 228 -1305 O ATOM 1077 N3 C A 10 31.068 41.699 61.898 1.00 45.71 N ANISOU 1077 N3 C A 10 5837 5170 6359 -429 -39 -1517 N ATOM 1078 C4 C A 10 32.089 41.817 62.752 1.00 46.84 C ANISOU 1078 C4 C A 10 5923 5360 6512 -444 -144 -1708 C ATOM 1079 N4 C A 10 32.655 40.695 63.205 1.00 46.97 N ANISOU 1079 N4 C A 10 5954 5493 6397 -398 -306 -1708 N ATOM 1080 C5 C A 10 32.573 43.090 63.178 1.00 48.28 C ANISOU 1080 C5 C A 10 6025 5478 6840 -503 -77 -1910 C ATOM 1081 C6 C A 10 31.962 44.174 62.682 1.00 48.50 C ANISOU 1081 C6 C A 10 6051 5368 7005 -532 115 -1881 C ATOM 1082 P G A 11 26.966 46.605 64.620 1.00 48.54 P ANISOU 1082 P G A 11 6373 5300 6766 -435 572 -1687 P ATOM 1083 OP1 G A 11 26.106 47.747 65.007 1.00 49.33 O ANISOU 1083 OP1 G A 11 6514 5312 6916 -420 760 -1701 O ATOM 1084 OP2 G A 11 27.794 45.936 65.650 1.00 49.09 O ANISOU 1084 OP2 G A 11 6441 5493 6718 -457 363 -1860 O ATOM 1085 O5' G A 11 26.081 45.486 63.897 1.00 46.02 O ANISOU 1085 O5' G A 11 6102 5081 6301 -377 525 -1422 O ATOM 1086 C5' G A 11 25.258 45.834 62.787 1.00 44.44 C ANISOU 1086 C5' G A 11 5887 4835 6161 -338 686 -1223 C ATOM 1087 C4' G A 11 24.538 44.617 62.241 1.00 42.40 C ANISOU 1087 C4' G A 11 5659 4707 5742 -310 604 -1029 C ATOM 1088 O4' G A 11 25.485 43.688 61.663 1.00 41.55 O ANISOU 1088 O4' G A 11 5517 4623 5645 -337 478 -1037 O ATOM 1089 C3' G A 11 23.808 43.783 63.279 1.00 41.79 C ANISOU 1089 C3' G A 11 5673 4752 5452 -298 492 -1010 C ATOM 1090 O3' G A 11 22.565 44.390 63.598 1.00 41.88 O ANISOU 1090 O3' G A 11 5723 4777 5412 -259 615 -928 O ATOM 1091 C2' G A 11 23.657 42.464 62.532 1.00 40.35 C ANISOU 1091 C2' G A 11 5494 4658 5176 -305 401 -875 C ATOM 1092 O2' G A 11 22.615 42.494 61.575 1.00 39.60 O ANISOU 1092 O2' G A 11 5374 4607 5062 -284 506 -695 O ATOM 1093 C1' G A 11 25.012 42.364 61.834 1.00 40.17 C ANISOU 1093 C1' G A 11 5403 4570 5288 -333 353 -949 C ATOM 1094 N9 G A 11 26.016 41.591 62.570 1.00 40.25 N ANISOU 1094 N9 G A 11 5433 4612 5245 -348 185 -1072 N ATOM 1095 C8 G A 11 26.998 42.076 63.403 1.00 41.16 C ANISOU 1095 C8 G A 11 5521 4702 5414 -361 127 -1266 C ATOM 1096 N7 G A 11 27.753 41.146 63.921 1.00 41.25 N ANISOU 1096 N7 G A 11 5546 4787 5340 -349 -28 -1324 N ATOM 1097 C5 G A 11 27.243 39.964 63.401 1.00 40.11 C ANISOU 1097 C5 G A 11 5454 4689 5094 -333 -61 -1157 C ATOM 1098 C6 G A 11 27.653 38.620 63.601 1.00 39.76 C ANISOU 1098 C6 G A 11 5455 4710 4942 -307 -183 -1120 C ATOM 1099 O6 G A 11 28.582 38.199 64.305 1.00 40.44 O ANISOU 1099 O6 G A 11 5535 4846 4983 -273 -300 -1212 O ATOM 1100 N1 G A 11 26.867 37.718 62.884 1.00 38.68 N ANISOU 1100 N1 G A 11 5365 4584 4745 -318 -150 -958 N ATOM 1101 C2 G A 11 25.813 38.072 62.072 1.00 38.23 C ANISOU 1101 C2 G A 11 5297 4515 4710 -347 -34 -849 C ATOM 1102 N2 G A 11 25.165 37.073 61.456 1.00 37.77 N ANISOU 1102 N2 G A 11 5274 4495 4582 -370 -23 -728 N ATOM 1103 N3 G A 11 25.420 39.325 61.875 1.00 38.57 N ANISOU 1103 N3 G A 11 5294 4521 4840 -350 74 -862 N ATOM 1104 C4 G A 11 26.174 40.220 62.568 1.00 39.55 C ANISOU 1104 C4 G A 11 5387 4597 5041 -343 63 -1016 C ATOM 1105 P C A 12 21.984 44.347 65.089 1.00 42.42 P ANISOU 1105 P C A 12 5882 4904 5329 -241 571 -996 P ATOM 1106 OP1 C A 12 21.175 45.571 65.287 1.00 43.24 O ANISOU 1106 OP1 C A 12 5995 4943 5489 -204 755 -978 O ATOM 1107 OP2 C A 12 23.074 44.023 66.045 1.00 42.70 O ANISOU 1107 OP2 C A 12 5935 4958 5329 -266 418 -1191 O ATOM 1108 O5' C A 12 20.986 43.106 64.980 1.00 41.38 O ANISOU 1108 O5' C A 12 5797 4905 5018 -227 507 -818 O ATOM 1109 C5' C A 12 20.947 42.121 65.990 1.00 41.36 C ANISOU 1109 C5' C A 12 5874 4989 4852 -222 375 -845 C ATOM 1110 C4' C A 12 20.793 40.750 65.370 1.00 40.24 C ANISOU 1110 C4' C A 12 5739 4913 4636 -246 299 -722 C ATOM 1111 O4' C A 12 21.948 40.446 64.544 1.00 39.74 O ANISOU 1111 O4' C A 12 5618 4802 4676 -277 236 -767 O ATOM 1112 C3' C A 12 20.747 39.630 66.391 1.00 40.49 C ANISOU 1112 C3' C A 12 5862 5017 4506 -228 188 -722 C ATOM 1113 O3' C A 12 19.422 39.453 66.854 1.00 40.78 O ANISOU 1113 O3' C A 12 5951 5116 4426 -211 251 -613 O ATOM 1114 C2' C A 12 21.239 38.450 65.565 1.00 39.55 C ANISOU 1114 C2' C A 12 5729 4901 4396 -264 118 -665 C ATOM 1115 O2' C A 12 20.243 37.946 64.697 1.00 38.79 O ANISOU 1115 O2' C A 12 5615 4843 4278 -305 185 -522 O ATOM 1116 C1' C A 12 22.360 39.106 64.759 1.00 39.29 C ANISOU 1116 C1' C A 12 5608 4791 4528 -283 113 -754 C ATOM 1117 N1 C A 12 23.720 39.071 65.428 1.00 39.92 N ANISOU 1117 N1 C A 12 5684 4855 4626 -263 -1 -911 N ATOM 1118 C2 C A 12 24.401 37.848 65.601 1.00 39.98 C ANISOU 1118 C2 C A 12 5726 4897 4565 -245 -116 -903 C ATOM 1119 O2 C A 12 23.898 36.787 65.209 1.00 39.43 O ANISOU 1119 O2 C A 12 5701 4845 4435 -258 -111 -778 O ATOM 1120 N3 C A 12 25.618 37.851 66.207 1.00 40.70 N ANISOU 1120 N3 C A 12 5794 5008 4661 -212 -222 -1037 N ATOM 1121 C4 C A 12 26.161 38.994 66.630 1.00 41.41 C ANISOU 1121 C4 C A 12 5825 5082 4824 -219 -221 -1199 C ATOM 1122 N4 C A 12 27.360 38.927 67.215 1.00 42.40 N ANISOU 1122 N4 C A 12 5909 5258 4941 -193 -337 -1342 N ATOM 1123 C5 C A 12 25.496 40.247 66.467 1.00 41.45 C ANISOU 1123 C5 C A 12 5807 5023 4918 -251 -91 -1224 C ATOM 1124 C6 C A 12 24.296 40.236 65.869 1.00 40.66 C ANISOU 1124 C6 C A 12 5735 4906 4807 -261 15 -1065 C ATOM 1125 P U A 13 19.092 39.557 68.417 1.00 42.10 P ANISOU 1125 P U A 13 6210 5330 4455 -150 231 -666 P ATOM 1126 OP1 U A 13 18.452 40.871 68.644 1.00 42.58 O ANISOU 1126 OP1 U A 13 6257 5364 4556 -128 352 -690 O ATOM 1127 OP2 U A 13 20.290 39.176 69.205 1.00 42.64 O ANISOU 1127 OP2 U A 13 6308 5414 4477 -116 98 -797 O ATOM 1128 O5' U A 13 17.988 38.412 68.595 1.00 41.48 O ANISOU 1128 O5' U A 13 6192 5322 4244 -153 249 -505 O ATOM 1129 C5' U A 13 18.273 37.054 68.271 1.00 40.47 C ANISOU 1129 C5' U A 13 6089 5202 4084 -182 186 -445 C ATOM 1130 C4' U A 13 17.245 36.129 68.896 1.00 40.77 C ANISOU 1130 C4' U A 13 6205 5292 3991 -173 224 -328 C ATOM 1131 O4' U A 13 16.420 36.859 69.842 1.00 41.74 O ANISOU 1131 O4' U A 13 6365 5457 4034 -119 286 -321 O ATOM 1132 C3' U A 13 16.256 35.512 67.918 1.00 39.83 C ANISOU 1132 C3' U A 13 6044 5196 3894 -262 302 -205 C ATOM 1133 O3' U A 13 16.793 34.310 67.382 1.00 38.75 O ANISOU 1133 O3' U A 13 5921 5023 3778 -310 258 -189 O ATOM 1134 C2' U A 13 15.051 35.235 68.814 1.00 40.77 C ANISOU 1134 C2' U A 13 6225 5370 3896 -240 374 -115 C ATOM 1135 O2' U A 13 15.174 34.047 69.573 1.00 41.28 O ANISOU 1135 O2' U A 13 6390 5420 3872 -214 353 -76 O ATOM 1136 C1' U A 13 15.072 36.430 69.760 1.00 41.71 C ANISOU 1136 C1' U A 13 6368 5500 3977 -152 381 -184 C ATOM 1137 N1 U A 13 14.168 37.569 69.348 1.00 42.13 N ANISOU 1137 N1 U A 13 6349 5581 4076 -158 486 -149 N ATOM 1138 C2 U A 13 12.795 37.458 69.538 1.00 42.72 C ANISOU 1138 C2 U A 13 6423 5726 4083 -165 584 -30 C ATOM 1139 O2 U A 13 12.246 36.480 70.022 1.00 43.34 O ANISOU 1139 O2 U A 13 6556 5835 4076 -179 597 42 O ATOM 1140 N3 U A 13 12.063 38.550 69.134 1.00 42.87 N ANISOU 1140 N3 U A 13 6367 5777 4144 -148 683 9 N ATOM 1141 C4 U A 13 12.550 39.720 68.575 1.00 42.80 C ANISOU 1141 C4 U A 13 6297 5718 4245 -123 711 -50 C ATOM 1142 O4 U A 13 11.767 40.611 68.265 1.00 43.31 O ANISOU 1142 O4 U A 13 6303 5815 4337 -91 826 16 O ATOM 1143 C5 U A 13 13.983 39.770 68.409 1.00 42.39 C ANISOU 1143 C5 U A 13 6253 5579 4272 -132 613 -182 C ATOM 1144 C6 U A 13 14.717 38.717 68.793 1.00 42.08 C ANISOU 1144 C6 U A 13 6275 5527 4184 -150 498 -227 C ATOM 1145 P U A 14 16.609 33.915 65.843 1.00 37.17 P ANISOU 1145 P U A 14 5630 4826 3666 -420 289 -155 P ATOM 1146 OP1 U A 14 16.969 32.486 65.735 1.00 37.47 O ANISOU 1146 OP1 U A 14 5729 4815 3694 -460 270 -136 O ATOM 1147 OP2 U A 14 17.316 34.916 65.016 1.00 36.15 O ANISOU 1147 OP2 U A 14 5411 4677 3644 -413 265 -219 O ATOM 1148 O5' U A 14 15.039 34.083 65.581 1.00 37.03 O ANISOU 1148 O5' U A 14 5558 4905 3607 -473 395 -60 O ATOM 1149 C5' U A 14 14.138 33.007 65.819 1.00 36.78 C ANISOU 1149 C5' U A 14 5563 4900 3510 -536 453 11 C ATOM 1150 C4' U A 14 12.699 33.455 65.647 1.00 36.62 C ANISOU 1150 C4' U A 14 5464 4997 3451 -571 547 87 C ATOM 1151 O4' U A 14 12.460 34.650 66.431 1.00 36.66 O ANISOU 1151 O4' U A 14 5483 5019 3424 -468 568 94 O ATOM 1152 C3' U A 14 12.300 33.872 64.240 1.00 36.02 C ANISOU 1152 C3' U A 14 5238 5022 3424 -635 574 101 C ATOM 1153 O3' U A 14 12.023 32.741 63.430 1.00 36.51 O ANISOU 1153 O3' U A 14 5258 5120 3493 -762 588 98 O ATOM 1154 C2' U A 14 11.046 34.690 64.532 1.00 36.32 C ANISOU 1154 C2' U A 14 5217 5174 3407 -599 661 182 C ATOM 1155 O2' U A 14 9.909 33.882 64.773 1.00 37.07 O ANISOU 1155 O2' U A 14 5301 5345 3436 -676 726 242 O ATOM 1156 C1' U A 14 11.451 35.427 65.810 1.00 36.31 C ANISOU 1156 C1' U A 14 5323 5086 3384 -479 647 158 C ATOM 1157 N1 U A 14 11.937 36.836 65.573 1.00 35.69 N ANISOU 1157 N1 U A 14 5202 4983 3372 -395 652 123 N ATOM 1158 C2 U A 14 11.050 37.895 65.716 1.00 35.92 C ANISOU 1158 C2 U A 14 5184 5078 3385 -332 750 188 C ATOM 1159 O2 U A 14 9.879 37.764 66.026 1.00 36.21 O ANISOU 1159 O2 U A 14 5201 5208 3346 -338 820 275 O ATOM 1160 N3 U A 14 11.588 39.142 65.475 1.00 35.76 N ANISOU 1160 N3 U A 14 5136 5001 3449 -259 779 151 N ATOM 1161 C4 U A 14 12.896 39.431 65.111 1.00 35.37 C ANISOU 1161 C4 U A 14 5092 4844 3500 -253 717 50 C ATOM 1162 O4 U A 14 13.240 40.594 64.926 1.00 35.66 O ANISOU 1162 O4 U A 14 5100 4823 3624 -193 775 22 O ATOM 1163 C5 U A 14 13.759 38.282 64.983 1.00 34.83 C ANISOU 1163 C5 U A 14 5065 4734 3434 -319 601 -12 C ATOM 1164 C6 U A 14 13.258 37.060 65.213 1.00 34.93 C ANISOU 1164 C6 U A 14 5115 4793 3364 -381 578 29 C TER 1165 U A 14 HETATM 1166 O HOH X 2 19.870 19.556 77.817 1.00 43.95 O ANISOU 1166 O HOH X 2 7667 6534 2497 224 -2819 1286 O HETATM 1167 O HOH X 3 8.741 9.082 58.407 1.00 40.89 O ANISOU 1167 O HOH X 3 5736 4326 5473 -1037 -822 59 O HETATM 1168 O HOH X 4 4.181 10.582 55.798 1.00 35.06 O ANISOU 1168 O HOH X 4 4207 4387 4728 -1593 -1203 -387 O HETATM 1169 O HOH X 5 16.473 40.337 58.045 1.00 30.73 O ANISOU 1169 O HOH X 5 5083 2500 4094 268 203 375 O HETATM 1170 O HOH X 6 15.062 28.895 63.182 1.00 20.84 O ANISOU 1170 O HOH X 6 2434 3330 2153 436 -250 -25 O HETATM 1171 O HOH X 7 16.828 30.816 53.827 1.00 32.61 O ANISOU 1171 O HOH X 7 4905 4298 3184 113 238 435 O HETATM 1172 O HOH X 9 18.470 18.865 57.741 1.00 25.05 O ANISOU 1172 O HOH X 9 3004 3409 3102 474 -242 -218 O HETATM 1173 O HOH X 10 4.613 37.994 63.172 1.00 39.44 O ANISOU 1173 O HOH X 10 4038 4873 6073 2168 -208 -587 O HETATM 1174 O HOH X 11 20.665 24.460 55.365 1.00 30.56 O ANISOU 1174 O HOH X 11 3691 4333 3587 186 477 -308 O HETATM 1175 O HOH X 12 -1.179 2.475 66.629 1.00 68.47 O ANISOU 1175 O HOH X 12 9292 6900 9822 -4953 1159 1562 O HETATM 1176 O HOH X 13 14.436 15.004 55.069 0.50 30.24 O HETATM 1177 O HOH X 14 8.127 6.604 56.448 1.00 37.68 O ANISOU 1177 O HOH X 14 5608 3373 5334 -1366 -981 -374 O HETATM 1178 O HOH X 17 7.706 36.980 50.088 1.00 43.56 O ANISOU 1178 O HOH X 17 7327 4771 4450 1554 -2029 1727 O HETATM 1179 O HOH X 18 11.787 34.276 78.556 1.00 62.11 O ANISOU 1179 O HOH X 18 9231 9492 4875 22 809 -2045 O HETATM 1180 O HOH X 19 17.131 6.068 54.234 1.00 34.31 O HETATM 1181 O HOH X 21 24.883 39.387 58.159 1.00 35.64 O ANISOU 1181 O HOH X 21 4684 3435 5422 -1310 1230 -338 O HETATM 1182 O HOH X 22 3.965 21.651 57.055 1.00 39.63 O ANISOU 1182 O HOH X 22 3906 6258 4892 -1 -1150 78 O HETATM 1183 O HOH A 15 30.133 41.308 65.889 1.00 37.47 O ANISOU 1183 O HOH A 15 4966 4436 4831 -344 -284 -1743 O HETATM 1184 O HOH A 16 9.038 40.812 66.807 1.00 35.07 O ANISOU 1184 O HOH A 16 4441 3762 5120 1632 358 -1283 O HETATM 1185 O HOH A 17 23.236 37.662 68.807 1.00 32.45 O ANISOU 1185 O HOH A 17 3810 4067 4452 -537 -672 -1598 O HETATM 1186 O HOH A 18 33.553 51.618 67.977 1.00 55.16 O ANISOU 1186 O HOH A 18 6614 5823 8520 -1084 666 -3618 O HETATM 1187 O HOH A 20 37.879 33.478 55.762 1.00 32.55 O ANISOU 1187 O HOH A 20 4055 3467 4844 -193 -418 -1048 O MASTER 350 0 0 3 8 0 0 6 1185 2 0 12 END
Display Options:
Goto PDB code:
3D presentation of molecule is powered by
3Dmol
, which supports all modern browsers and mobile devices via WebGL.
Hold mouse button:
left to rotate,middle to shift,right to zoom
Related entries of code: 3o3i
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
3o6e
RCSB PDB
PDBbind
14aa, >3O6E_2|Chain... at 100%
4ngb
RCSB PDB
PDBbind
12aa, >4NGB_2|Chain... at 100%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
3o3i
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
human Hiwi1 PAZ domain (residues 277-399)
Ligand Name
14-mer RNA (12-bp and 2-nt overhang) containing 2'-OH at its 3'-end
EC.Number
E.C.-.-.-.-
Resolution
2.8(Å)
Affinity (Kd/Ki/IC50)
Kd=16.6uM
Release Year
2011
Protein/NA Sequence
Check fasta file
Primary Reference
(2011) Proc.Natl.Acad.Sci.USA Vol. 108: pp. 903-910
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q96J94
Entrez Gene ID
NCBI Entrez Gene ID:
9271
ASD
Information of known allosteric effects of PDB entries
This site has been visited
times since Nov 2007.
Copyright ©2007-2024 涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃 缃戠珯澶囨鍙凤細
娌狪CP澶2021015625鍙-3
娌叕缃戝畨澶囷細
姝ｅ湪鐢宠涓
Technical Support锛堟妧鏈敮鎸侊級:
yingsaisi@foxmail.com
times since Nov 2007. 
娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓