Browse entries in the PDBbind-CN Database
HEADER RNA BINDING PROTEIN/RNA 28-JUL-10 3O6E TITLE CRYSTAL STRUCTURE OF HUMAN HIWI1 PAZ DOMAIN (RESIDUES 277-399) IN TITLE 2 COMPLEX WITH 14-MER RNA (12-BP + 2-NT OVERHANG) CONTAINING 2'-OCH3 AT TITLE 3 ITS 3'-END COMPND MOL_ID: 1; COMPND 2 MOLECULE: PIWI-LIKE PROTEIN 1; COMPND 3 CHAIN: X; COMPND 4 FRAGMENT: PAZ DOMAIN (UNP RESIDUES 277-399); COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*(OMU))- COMPND 8 3'); COMPND 9 CHAIN: A; COMPND 10 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: HIWI, PIWI-LIKE PROTEIN 1, PIWIL1; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3); SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PET-28B; SOURCE 11 MOL_ID: 2; SOURCE 12 SYNTHETIC: YES; SOURCE 13 OTHER_DETAILS: CHEMICALLY SYNTHESIZED KEYWDS PIWI, PAZ, RNA SILENCING, PI-RNA, HIWI1, HILI, PAZ DOMAIN, RNA KEYWDS 2 BINDING PROTEIN-RNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR Y.TIAN,D.K.SIMANSHU,J.-B.MA,D.J.PATEL REVDAT 3 08-NOV-17 3O6E 1 REMARK REVDAT 2 02-FEB-11 3O6E 1 JRNL REVDAT 1 12-JAN-11 3O6E 0 JRNL AUTH Y.TIAN,D.K.SIMANSHU,J.B.MA,D.J.PATEL JRNL TITL INAUGURAL ARTICLE: STRUCTURAL BASIS FOR PIRNA JRNL TITL 2 2'-O-METHYLATED 3'-END RECOGNITION BY PIWI PAZ JRNL TITL 3 (PIWI/ARGONAUTE/ZWILLE) DOMAINS. JRNL REF PROC.NATL.ACAD.SCI.USA V. 108 903 2011 JRNL REFN ISSN 0027-8424 JRNL PMID 21193640 JRNL DOI 10.1073/PNAS.1017762108 REMARK 2 REMARK 2 RESOLUTION. 2.90 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.90 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 15.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : 95.3 REMARK 3 NUMBER OF REFLECTIONS : 3384 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.256 REMARK 3 R VALUE (WORKING SET) : 0.252 REMARK 3 FREE R VALUE : 0.305 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 9.000 REMARK 3 FREE R VALUE TEST SET COUNT : 305 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.90 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.98 REMARK 3 REFLECTION IN BIN (WORKING SET) : 154 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 67.76 REMARK 3 BIN R VALUE (WORKING SET) : 0.3320 REMARK 3 BIN FREE R VALUE SET COUNT : 12 REMARK 3 BIN FREE R VALUE : 0.3690 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 855 REMARK 3 NUCLEIC ACID ATOMS : 293 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 6 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 61.55 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 2.55000 REMARK 3 B22 (A**2) : 2.55000 REMARK 3 B33 (A**2) : -5.10000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): NULL REMARK 3 ESU BASED ON FREE R VALUE (A): 0.569 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.418 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 51.553 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.911 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.866 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1200 ; 0.005 ; 0.022 REMARK 3 BOND LENGTHS OTHERS (A): NULL ; NULL ; NULL REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 1691 ; 0.842 ; 2.271 REMARK 3 BOND ANGLES OTHERS (DEGREES): NULL ; NULL ; NULL REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 105 ; 4.211 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 41 ;35.208 ;25.366 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 147 ;13.429 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 2 ; 2.725 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 202 ; 0.050 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 800 ; 0.003 ; 0.021 REMARK 3 GENERAL PLANES OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 534 ; 0.131 ; 1.500 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 863 ; 0.258 ; 2.000 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 666 ; 0.338 ; 3.000 REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): 828 ; 0.522 ; 4.500 REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 2 REMARK 3 REMARK 3 TLS GROUP : 1 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : X -10 X 9999 REMARK 3 ORIGIN FOR THE GROUP (A): 11.2839 24.3383 63.0024 REMARK 3 T TENSOR REMARK 3 T11: 0.1334 T22: 0.2500 REMARK 3 T33: 0.1342 T12: 0.0243 REMARK 3 T13: -0.0134 T23: 0.0023 REMARK 3 L TENSOR REMARK 3 L11: 2.9781 L22: 4.8142 REMARK 3 L33: 3.8322 L12: 0.0899 REMARK 3 L13: 0.4285 L23: 0.6699 REMARK 3 S TENSOR REMARK 3 S11: 0.1470 S12: -0.2495 S13: -0.0741 REMARK 3 S21: 0.3084 S22: -0.1001 S23: 0.3432 REMARK 3 S31: 0.1743 S32: -0.4318 S33: -0.0468 REMARK 3 REMARK 3 TLS GROUP : 2 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : A -10 A 9999 REMARK 3 ORIGIN FOR THE GROUP (A): 32.0514 36.5411 58.4970 REMARK 3 T TENSOR REMARK 3 T11: 0.2757 T22: 0.2757 REMARK 3 T33: 0.4162 T12: 0.0068 REMARK 3 T13: 0.0015 T23: -0.0854 REMARK 3 L TENSOR REMARK 3 L11: 2.6964 L22: 2.3205 REMARK 3 L33: 0.7537 L12: -1.8196 REMARK 3 L13: -1.4253 L23: 0.9672 REMARK 3 S TENSOR REMARK 3 S11: -0.1590 S12: -0.2986 S13: 0.4047 REMARK 3 S21: 0.1759 S22: 0.3628 S23: -0.5886 REMARK 3 S31: 0.0919 S32: 0.1599 S33: -0.2038 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.40 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS U VALUES : WITH TLS ADDED REMARK 4 REMARK 4 3O6E COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 03-AUG-10. REMARK 100 THE DEPOSITION ID IS D_1000060722. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 15-SEP-09 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 4.6 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : NSLS REMARK 200 BEAMLINE : X29A REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9792 REMARK 200 MONOCHROMATOR : ROSENBAUM-ROCK DOUBLE CRYSTAL REMARK 200 SAGITTAL FOCUSING MONOCHROMATOR REMARK 200 OPTICS : VERTICAL FOCUSING MIRROR REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 315 REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO, HKL-2000 REMARK 200 DATA SCALING SOFTWARE : SCALEPACK, HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 3451 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.900 REMARK 200 RESOLUTION RANGE LOW (A) : 30.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 95.3 REMARK 200 DATA REDUNDANCY : 10.40 REMARK 200 R MERGE (I) : 0.08300 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 32.5000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.90 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 3.00 REMARK 200 COMPLETENESS FOR SHELL (%) : 72.3 REMARK 200 DATA REDUNDANCY IN SHELL : 6.20 REMARK 200 R MERGE FOR SHELL (I) : 0.20900 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 4.800 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: DIFFERENCE FOURIER REMARK 200 STARTING MODEL: PDB ENTRY 3O7V REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 34.13 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 1.87 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 1-5% PEG3350, 50 MM NACL, 50 MM NA REMARK 280 -ACETATE BUFFER, PH 4.6, VAPOR DIFFUSION, HANGING DROP, REMARK 280 TEMPERATURE 277K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 41 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -Y,X,Z+1/4 REMARK 290 4555 Y,-X,Z+3/4 REMARK 290 5555 -X,Y,-Z REMARK 290 6555 X,-Y,-Z+1/2 REMARK 290 7555 Y,X,-Z+3/4 REMARK 290 8555 -Y,-X,-Z+1/4 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 73.51200 REMARK 290 SMTRY1 3 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 36.75600 REMARK 290 SMTRY1 4 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 110.26800 REMARK 290 SMTRY1 5 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 6 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 -1.000000 73.51200 REMARK 290 SMTRY1 7 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 7 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 110.26800 REMARK 290 SMTRY1 8 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 36.75600 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 5940 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 14860 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -31.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: X, A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMT1 2 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT2 2 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT3 2 0.000000 0.000000 -1.000000 110.26800 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 SER X 276 REMARK 465 ARG X 368 REMARK 465 ARG X 369 REMARK 465 ARG X 370 REMARK 465 GLY X 371 REMARK 465 PRO X 372 REMARK 465 GLY X 373 REMARK 465 GLY X 374 REMARK 465 THR X 375 REMARK 465 LEU X 376 REMARK 465 PRO X 377 REMARK 465 ASP X 394 REMARK 465 LYS X 395 REMARK 465 MET X 396 REMARK 465 ARG X 397 REMARK 465 ASN X 398 REMARK 465 ASP X 399 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 PHE X 284 CG CD1 CD2 CE1 CE2 CZ REMARK 470 GLN X 289 CG CD OE1 NE2 REMARK 470 LYS X 294 CG CD CE NZ REMARK 470 GLN X 298 OE1 NE2 REMARK 470 LYS X 301 CG CD CE NZ REMARK 470 GLU X 302 CG CD OE1 OE2 REMARK 470 GLU X 339 CG CD OE1 OE2 REMARK 470 GLU X 353 CG CD OE1 OE2 REMARK 470 LEU X 392 CG CD1 CD2 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASN X 285 -53.53 -120.65 REMARK 500 PRO X 366 -157.61 -94.29 REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 3O3I RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF HUMAN HIWI1 PAZ DOMAIN (RESIDUES 277-399) IN REMARK 900 COMPLEX WITH 14-MER RNA (12-BP + 2-NT OVERHANG) CONTAINING 2'-OH AT REMARK 900 ITS 3'-END REMARK 900 RELATED ID: 3O7V RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF HUMAN HIWI1 (V361M) PAZ DOMAIN (RESIDUES 277- REMARK 900 399) IN COMPLEX WITH 14-MER RNA (12-BP + 2-NT OVERHANG) CONTAINING REMARK 900 2'-OCH3 AT ITS 3'-END REMARK 900 RELATED ID: 3O7X RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF HUMAN HILI PAZ DOMAIN (RESIDUES 277-399) DBREF 3O6E X 277 399 UNP Q96J94 PIWL1_HUMAN 277 399 DBREF 3O6E A 1 14 PDB 3O6E 3O6E 1 14 SEQADV 3O6E SER X 276 UNP Q96J94 EXPRESSION TAG SEQRES 1 X 124 SER GLU THR VAL LEU ASP PHE MSE PHE ASN PHE TYR HIS SEQRES 2 X 124 GLN THR GLU GLU HIS LYS PHE GLN GLU GLN VAL SER LYS SEQRES 3 X 124 GLU LEU ILE GLY LEU VAL VAL LEU THR LYS TYR ASN ASN SEQRES 4 X 124 LYS THR TYR ARG VAL ASP ASP ILE ASP TRP ASP GLN ASN SEQRES 5 X 124 PRO LYS SER THR PHE LYS LYS ALA ASP GLY SER GLU VAL SEQRES 6 X 124 SER PHE LEU GLU TYR TYR ARG LYS GLN TYR ASN GLN GLU SEQRES 7 X 124 ILE THR ASP LEU LYS GLN PRO VAL LEU VAL SER GLN PRO SEQRES 8 X 124 LYS ARG ARG ARG GLY PRO GLY GLY THR LEU PRO GLY PRO SEQRES 9 X 124 ALA MSE LEU ILE PRO GLU LEU CYS TYR LEU THR GLY LEU SEQRES 10 X 124 THR ASP LYS MET ARG ASN ASP SEQRES 1 A 14 G C G A A U A U U C G C U SEQRES 2 A 14 OMU MODRES 3O6E MSE X 283 MET SELENOMETHIONINE MODRES 3O6E MSE X 381 MET SELENOMETHIONINE MODRES 3O6E OMU A 14 U O2'-METHYLURIDINE 5'-MONOPHOSPHATE HET MSE X 283 8 HET MSE X 381 8 HET OMU A 14 21 HETNAM MSE SELENOMETHIONINE HETNAM OMU O2'-METHYLURIDINE 5'-MONOPHOSPHATE FORMUL 1 MSE 2(C5 H11 N O2 SE) FORMUL 2 OMU C10 H15 N2 O9 P FORMUL 3 HOH *6(H2 O) HELIX 1 1 THR X 278 PHE X 284 1 7 HELIX 2 2 GLU X 291 ILE X 304 1 14 HELIX 3 3 PHE X 342 GLN X 349 1 8 HELIX 4 4 ILE X 383 GLU X 385 5 3 SHEET 1 A 3 THR X 316 ARG X 318 0 SHEET 2 A 3 VAL X 307 THR X 310 -1 N VAL X 308 O TYR X 317 SHEET 3 A 3 CYS X 387 LEU X 389 -1 O TYR X 388 N LEU X 309 SHEET 1 B 3 ASP X 321 ASP X 323 0 SHEET 2 B 3 VAL X 361 SER X 364 -1 O VAL X 363 N ASP X 321 SHEET 3 B 3 ALA X 380 LEU X 382 -1 O LEU X 382 N LEU X 362 SHEET 1 C 2 THR X 331 LYS X 333 0 SHEET 2 C 2 GLU X 339 SER X 341 -1 O VAL X 340 N PHE X 332 LINK C PHE X 282 N MSE X 283 1555 1555 1.33 LINK C MSE X 283 N PHE X 284 1555 1555 1.33 LINK C ALA X 380 N MSE X 381 1555 1555 1.33 LINK C MSE X 381 N LEU X 382 1555 1555 1.33 LINK O3' U A 13 P OMU A 14 1555 1555 1.60 CRYST1 44.013 44.013 147.024 90.00 90.00 90.00 P 41 2 2 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.022721 0.000000 0.000000 0.00000 SCALE2 0.000000 0.022721 0.000000 0.00000 SCALE3 0.000000 0.000000 0.006802 0.00000 ATOM 1 N GLU X 277 22.819 15.985 63.563 1.00 56.71 N ANISOU 1 N GLU X 277 7289 6897 7360 1071 -1388 148 N ATOM 2 CA GLU X 277 21.465 15.609 63.060 1.00 55.86 C ANISOU 2 CA GLU X 277 7321 6736 7165 930 -1263 175 C ATOM 3 C GLU X 277 20.450 16.718 63.336 1.00 54.17 C ANISOU 3 C GLU X 277 7090 6687 6804 751 -1129 205 C ATOM 4 O GLU X 277 20.357 17.224 64.458 1.00 54.29 O ANISOU 4 O GLU X 277 7153 6770 6705 686 -1170 281 O ATOM 5 CB GLU X 277 21.001 14.287 63.689 1.00 57.57 C ANISOU 5 CB GLU X 277 7788 6738 7345 895 -1387 304 C ATOM 6 CG GLU X 277 19.708 13.718 63.092 1.00 57.27 C ANISOU 6 CG GLU X 277 7866 6619 7274 739 -1282 312 C ATOM 7 CD GLU X 277 19.135 12.540 63.877 1.00 59.38 C ANISOU 7 CD GLU X 277 8395 6672 7494 636 -1377 470 C ATOM 8 OE1 GLU X 277 19.338 12.470 65.110 1.00 60.41 O ANISOU 8 OE1 GLU X 277 8652 6779 7521 619 -1477 616 O ATOM 9 OE2 GLU X 277 18.466 11.686 63.257 1.00 60.13 O ANISOU 9 OE2 GLU X 277 8589 6612 7642 557 -1355 449 O ATOM 10 N THR X 278 19.694 17.090 62.306 1.00 52.95 N ANISOU 10 N THR X 278 6878 6594 6646 688 -979 136 N ATOM 11 CA THR X 278 18.661 18.114 62.443 1.00 51.67 C ANISOU 11 CA THR X 278 6680 6573 6378 554 -858 151 C ATOM 12 C THR X 278 17.305 17.499 62.792 1.00 52.32 C ANISOU 12 C THR X 278 6880 6612 6387 399 -828 232 C ATOM 13 O THR X 278 17.132 16.276 62.737 1.00 53.55 O ANISOU 13 O THR X 278 7158 6610 6577 374 -895 273 O ATOM 14 CB THR X 278 18.538 19.008 61.177 1.00 50.35 C ANISOU 14 CB THR X 278 6383 6507 6241 576 -733 49 C ATOM 15 OG1 THR X 278 18.063 18.233 60.070 1.00 50.60 O ANISOU 15 OG1 THR X 278 6457 6468 6301 579 -718 -1 O ATOM 16 CG2 THR X 278 19.877 19.641 60.821 1.00 50.07 C ANISOU 16 CG2 THR X 278 6219 6517 6286 689 -719 -22 C ATOM 17 N VAL X 279 16.355 18.357 63.158 1.00 51.89 N ANISOU 17 N VAL X 279 6777 6688 6247 294 -720 249 N ATOM 18 CA VAL X 279 15.001 17.938 63.529 1.00 52.82 C ANISOU 18 CA VAL X 279 6943 6811 6315 128 -650 314 C ATOM 19 C VAL X 279 14.245 17.354 62.327 1.00 53.15 C ANISOU 19 C VAL X 279 6942 6805 6448 78 -645 257 C ATOM 20 O VAL X 279 13.499 16.380 62.464 1.00 54.43 O ANISOU 20 O VAL X 279 7177 6872 6628 -57 -654 310 O ATOM 21 CB VAL X 279 14.205 19.110 64.166 1.00 52.36 C ANISOU 21 CB VAL X 279 6801 6923 6167 64 -516 311 C ATOM 22 CG1 VAL X 279 12.795 18.680 64.545 1.00 53.57 C ANISOU 22 CG1 VAL X 279 6949 7109 6295 -111 -410 367 C ATOM 23 CG2 VAL X 279 14.934 19.652 65.386 1.00 52.49 C ANISOU 23 CG2 VAL X 279 6899 6979 6066 99 -540 345 C ATOM 24 N LEU X 280 14.452 17.948 61.154 1.00 52.40 N ANISOU 24 N LEU X 280 6744 6766 6397 176 -637 151 N ATOM 25 CA LEU X 280 13.857 17.447 59.918 1.00 53.12 C ANISOU 25 CA LEU X 280 6821 6820 6541 150 -666 75 C ATOM 26 C LEU X 280 14.327 16.021 59.624 1.00 54.71 C ANISOU 26 C LEU X 280 7169 6817 6801 162 -765 60 C ATOM 27 O LEU X 280 13.523 15.168 59.239 1.00 55.91 O ANISOU 27 O LEU X 280 7370 6878 6993 45 -808 41 O ATOM 28 CB LEU X 280 14.177 18.380 58.742 1.00 52.06 C ANISOU 28 CB LEU X 280 6606 6778 6394 269 -640 -19 C ATOM 29 CG LEU X 280 13.620 18.030 57.355 1.00 52.53 C ANISOU 29 CG LEU X 280 6678 6824 6455 264 -690 -110 C ATOM 30 CD1 LEU X 280 12.103 18.194 57.295 1.00 53.06 C ANISOU 30 CD1 LEU X 280 6649 6974 6537 136 -709 -103 C ATOM 31 CD2 LEU X 280 14.295 18.865 56.276 1.00 51.77 C ANISOU 31 CD2 LEU X 280 6571 6795 6302 398 -649 -177 C ATOM 32 N ASP X 281 15.625 15.776 59.816 1.00 55.20 N ANISOU 32 N ASP X 281 7288 6798 6887 305 -809 56 N ATOM 33 CA ASP X 281 16.206 14.441 59.663 1.00 57.16 C ANISOU 33 CA ASP X 281 7680 6825 7210 365 -911 39 C ATOM 34 C ASP X 281 15.515 13.456 60.600 1.00 59.13 C ANISOU 34 C ASP X 281 8081 6923 7460 204 -966 168 C ATOM 35 O ASP X 281 15.137 12.362 60.188 1.00 60.61 O ANISOU 35 O ASP X 281 8390 6925 7711 137 -1028 144 O ATOM 36 CB ASP X 281 17.714 14.459 59.952 1.00 57.28 C ANISOU 36 CB ASP X 281 7682 6805 7275 563 -958 27 C ATOM 37 CG ASP X 281 18.496 15.356 58.999 1.00 56.07 C ANISOU 37 CG ASP X 281 7377 6789 7137 697 -870 -95 C ATOM 38 OD1 ASP X 281 17.955 15.770 57.953 1.00 55.63 O ANISOU 38 OD1 ASP X 281 7287 6814 7035 665 -792 -174 O ATOM 39 OD2 ASP X 281 19.670 15.648 59.302 1.00 55.55 O ANISOU 39 OD2 ASP X 281 7226 6750 7129 828 -884 -107 O ATOM 40 N PHE X 282 15.342 13.876 61.853 1.00 59.65 N ANISOU 40 N PHE X 282 8155 7064 7443 128 -933 302 N ATOM 41 CA PHE X 282 14.692 13.085 62.901 1.00 62.06 C ANISOU 41 CA PHE X 282 8621 7253 7703 -48 -942 459 C ATOM 42 C PHE X 282 13.268 12.647 62.535 1.00 63.36 C ANISOU 42 C PHE X 282 8764 7402 7908 -281 -874 456 C ATOM 43 O PHE X 282 12.853 11.532 62.868 1.00 65.51 O ANISOU 43 O PHE X 282 9201 7475 8213 -432 -911 546 O ATOM 44 CB PHE X 282 14.690 13.885 64.211 1.00 61.80 C ANISOU 44 CB PHE X 282 8588 7369 7524 -86 -877 571 C ATOM 45 CG PHE X 282 14.110 13.146 65.387 1.00 64.33 C ANISOU 45 CG PHE X 282 9108 7590 7744 -270 -856 754 C ATOM 46 CD1 PHE X 282 14.910 12.314 66.167 1.00 66.41 C ANISOU 46 CD1 PHE X 282 9612 7658 7961 -209 -1002 885 C ATOM 47 CD2 PHE X 282 12.768 13.300 65.731 1.00 65.20 C ANISOU 47 CD2 PHE X 282 9163 7805 7804 -503 -683 801 C ATOM 48 CE1 PHE X 282 14.381 11.637 67.264 1.00 68.85 C ANISOU 48 CE1 PHE X 282 10154 7864 8142 -393 -974 1083 C ATOM 49 CE2 PHE X 282 12.228 12.624 66.823 1.00 67.78 C ANISOU 49 CE2 PHE X 282 9683 8049 8021 -702 -619 982 C ATOM 50 CZ PHE X 282 13.037 11.792 67.592 1.00 69.56 C ANISOU 50 CZ PHE X 282 10199 8066 8165 -655 -761 1134 C HETATM 51 N MSE X 283 12.529 13.527 61.859 1.00 62.59 N ANISOU 51 N MSE X 283 8459 7503 7819 -314 -791 357 N HETATM 52 CA MSE X 283 11.156 13.244 61.434 1.00 64.18 C ANISOU 52 CA MSE X 283 8568 7730 8085 -523 -752 328 C HETATM 53 C MSE X 283 11.094 12.091 60.437 1.00 65.57 C ANISOU 53 C MSE X 283 8851 7692 8369 -562 -881 239 C HETATM 54 O MSE X 283 10.235 11.213 60.542 1.00 67.75 O ANISOU 54 O MSE X 283 9176 7844 8718 -787 -894 276 O HETATM 55 CB MSE X 283 10.522 14.488 60.817 1.00 62.95 C ANISOU 55 CB MSE X 283 8167 7824 7926 -485 -686 230 C HETATM 56 CG MSE X 283 10.294 15.626 61.795 1.00 63.49 C ANISOU 56 CG MSE X 283 8124 8091 7909 -476 -543 291 C HETATM 57 SE MSE X 283 9.806 17.274 60.873 1.00 65.26 SE ANISOU 57 SE MSE X 283 8088 8561 8146 -339 -506 162 SE HETATM 58 CE MSE X 283 9.391 18.381 62.421 1.00 64.38 C ANISOU 58 CE MSE X 283 7891 8628 7942 -363 -306 233 C ATOM 59 N PHE X 284 12.015 12.100 59.479 1.00 64.81 N ANISOU 59 N PHE X 284 8794 7548 8282 -353 -962 112 N ATOM 60 CA PHE X 284 12.081 11.071 58.447 1.00 66.32 C ANISOU 60 CA PHE X 284 9111 7536 8549 -347 -1080 -15 C ATOM 61 C PHE X 284 12.919 9.861 58.872 1.00 68.08 C ANISOU 61 C PHE X 284 9581 7454 8831 -284 -1165 34 C ATOM 62 O PHE X 284 13.161 8.960 58.065 1.00 69.54 O ANISOU 62 O PHE X 284 9905 7432 9086 -235 -1261 -89 O ATOM 63 CB PHE X 284 12.631 11.669 57.149 1.00 65.07 C ANISOU 63 CB PHE X 284 8894 7485 8345 -148 -1094 -189 C ATOM 64 N ASN X 285 13.350 9.839 60.134 1.00 68.31 N ANISOU 64 N ASN X 285 9681 7447 8824 -273 -1144 209 N ATOM 65 CA ASN X 285 14.209 8.766 60.646 1.00 70.31 C ANISOU 65 CA ASN X 285 10176 7407 9129 -176 -1257 286 C ATOM 66 C ASN X 285 13.637 7.978 61.826 1.00 72.67 C ANISOU 66 C ASN X 285 10669 7527 9413 -399 -1266 505 C ATOM 67 O ASN X 285 13.571 6.749 61.773 1.00 75.30 O ANISOU 67 O ASN X 285 11229 7541 9839 -468 -1364 534 O ATOM 68 CB ASN X 285 15.604 9.298 61.012 1.00 69.17 C ANISOU 68 CB ASN X 285 9993 7333 8956 105 -1288 295 C ATOM 69 CG ASN X 285 16.488 9.546 59.795 1.00 68.33 C ANISOU 69 CG ASN X 285 9783 7271 8907 348 -1291 83 C ATOM 70 OD1 ASN X 285 17.337 10.437 59.814 1.00 66.90 O ANISOU 70 OD1 ASN X 285 9450 7268 8701 514 -1250 51 O ATOM 71 ND2 ASN X 285 16.302 8.755 58.741 1.00 69.46 N ANISOU 71 ND2 ASN X 285 10018 7251 9123 355 -1331 -68 N ATOM 72 N PHE X 286 13.235 8.681 62.885 1.00 72.19 N ANISOU 72 N PHE X 286 10545 7657 9225 -514 -1154 657 N ATOM 73 CA PHE X 286 12.835 8.030 64.140 1.00 74.68 C ANISOU 73 CA PHE X 286 11078 7829 9468 -713 -1130 893 C ATOM 74 C PHE X 286 11.530 7.240 64.033 1.00 76.92 C ANISOU 74 C PHE X 286 11408 7984 9831 -1056 -1062 937 C ATOM 75 O PHE X 286 11.404 6.171 64.640 1.00 79.85 O ANISOU 75 O PHE X 286 12053 8071 10215 -1207 -1103 1103 O ATOM 76 CB PHE X 286 12.761 9.038 65.291 1.00 73.84 C ANISOU 76 CB PHE X 286 10905 7981 9168 -740 -1004 1017 C ATOM 77 CG PHE X 286 12.954 8.421 66.657 1.00 76.77 C ANISOU 77 CG PHE X 286 11577 8194 9396 -820 -1033 1268 C ATOM 78 CD1 PHE X 286 11.858 8.145 67.473 1.00 79.25 C ANISOU 78 CD1 PHE X 286 11983 8513 9612 -1139 -863 1436 C ATOM 79 CD2 PHE X 286 14.232 8.119 67.128 1.00 77.68 C ANISOU 79 CD2 PHE X 286 11881 8161 9470 -576 -1232 1340 C ATOM 80 CE1 PHE X 286 12.032 7.574 68.739 1.00 82.04 C ANISOU 80 CE1 PHE X 286 12665 8718 9787 -1224 -879 1690 C ATOM 81 CE2 PHE X 286 14.417 7.550 68.391 1.00 80.52 C ANISOU 81 CE2 PHE X 286 12559 8368 9666 -637 -1295 1589 C ATOM 82 CZ PHE X 286 13.314 7.276 69.197 1.00 82.67 C ANISOU 82 CZ PHE X 286 12973 8637 9800 -967 -1113 1773 C ATOM 83 N TYR X 287 10.568 7.763 63.272 1.00 75.86 N ANISOU 83 N TYR X 287 11011 8050 9761 -1184 -972 796 N ATOM 84 CA TYR X 287 9.337 7.020 62.981 1.00 78.14 C ANISOU 84 CA TYR X 287 11282 8231 10176 -1513 -939 791 C ATOM 85 C TYR X 287 8.822 7.247 61.557 1.00 77.20 C ANISOU 85 C TYR X 287 10943 8210 10179 -1510 -1006 545 C ATOM 86 O TYR X 287 8.723 8.388 61.091 1.00 74.75 O ANISOU 86 O TYR X 287 10379 8197 9824 -1382 -962 433 O ATOM 87 CB TYR X 287 8.242 7.315 64.017 1.00 79.44 C ANISOU 87 CB TYR X 287 11342 8565 10276 -1810 -717 953 C ATOM 88 CG TYR X 287 7.393 6.103 64.354 1.00 83.36 C ANISOU 88 CG TYR X 287 11993 8805 10873 -2179 -678 1082 C ATOM 89 CD1 TYR X 287 7.809 5.183 65.321 1.00 85.85 C ANISOU 89 CD1 TYR X 287 12682 8825 11111 -2259 -692 1318 C ATOM 90 CD2 TYR X 287 6.181 5.869 63.703 1.00 84.91 C ANISOU 90 CD2 TYR X 287 11970 9041 11249 -2459 -645 975 C ATOM 91 CE1 TYR X 287 7.039 4.064 65.633 1.00 89.74 C ANISOU 91 CE1 TYR X 287 13347 9049 11698 -2626 -645 1457 C ATOM 92 CE2 TYR X 287 5.402 4.750 64.008 1.00 88.81 C ANISOU 92 CE2 TYR X 287 12593 9287 11862 -2838 -603 1091 C ATOM 93 CZ TYR X 287 5.837 3.855 64.974 1.00 91.24 C ANISOU 93 CZ TYR X 287 13295 9284 12086 -2929 -588 1338 C ATOM 94 OH TYR X 287 5.072 2.751 65.280 1.00 95.39 O ANISOU 94 OH TYR X 287 13977 9535 12730 -3331 -533 1473 O ATOM 95 N HIS X 288 8.511 6.143 60.876 1.00 79.38 N ANISOU 95 N HIS X 288 11350 8212 10597 -1648 -1132 463 N ATOM 96 CA HIS X 288 7.945 6.176 59.527 1.00 79.25 C ANISOU 96 CA HIS X 288 11179 8253 10677 -1682 -1236 225 C ATOM 97 C HIS X 288 6.491 5.717 59.542 1.00 81.84 C ANISOU 97 C HIS X 288 11374 8572 11149 -2084 -1208 234 C ATOM 98 O HIS X 288 6.188 4.589 59.945 1.00 84.97 O ANISOU 98 O HIS X 288 11970 8668 11646 -2335 -1226 331 O ATOM 99 CB HIS X 288 8.751 5.306 58.552 1.00 80.14 C ANISOU 99 CB HIS X 288 11536 8069 10841 -1511 -1424 55 C ATOM 100 CG HIS X 288 10.229 5.322 58.791 1.00 78.93 C ANISOU 100 CG HIS X 288 11558 7820 10611 -1166 -1446 85 C ATOM 101 ND1 HIS X 288 10.963 6.486 58.861 1.00 76.11 N ANISOU 101 ND1 HIS X 288 11045 7741 10132 -906 -1372 80 N ATOM 102 CD2 HIS X 288 11.112 4.310 58.957 1.00 80.87 C ANISOU 102 CD2 HIS X 288 12102 7713 10910 -1034 -1549 111 C ATOM 103 CE1 HIS X 288 12.233 6.191 59.071 1.00 76.04 C ANISOU 103 CE1 HIS X 288 11200 7579 10112 -644 -1425 98 C ATOM 104 NE2 HIS X 288 12.351 4.877 59.134 1.00 79.00 N ANISOU 104 NE2 HIS X 288 11848 7574 10593 -696 -1537 117 N ATOM 105 N GLN X 289 5.597 6.597 59.102 1.00 80.72 N ANISOU 105 N GLN X 289 10885 8751 11033 -2145 -1172 136 N ATOM 106 CA GLN X 289 4.175 6.286 59.049 1.00 83.29 C ANISOU 106 CA GLN X 289 10991 9126 11529 -2515 -1154 116 C ATOM 107 C GLN X 289 3.572 6.710 57.717 1.00 82.97 C ANISOU 107 C GLN X 289 10711 9259 11554 -2482 -1331 -127 C ATOM 108 O GLN X 289 3.721 7.859 57.294 1.00 80.31 O ANISOU 108 O GLN X 289 10195 9202 11117 -2235 -1333 -199 O ATOM 109 CB GLN X 289 3.433 6.949 60.213 1.00 83.56 C ANISOU 109 CB GLN X 289 10783 9417 11549 -2674 -890 289 C ATOM 110 N THR X 290 2.900 5.769 57.060 1.00 85.93 N ANISOU 110 N THR X 290 11108 9448 12092 -2736 -1499 -250 N ATOM 111 CA THR X 290 2.227 6.033 55.786 1.00 86.42 C ANISOU 111 CA THR X 290 10967 9655 12211 -2744 -1718 -488 C ATOM 112 C THR X 290 0.926 6.825 55.983 1.00 87.09 C ANISOU 112 C THR X 290 10576 10090 12423 -2911 -1651 -478 C ATOM 113 O THR X 290 0.503 7.563 55.093 1.00 86.62 O ANISOU 113 O THR X 290 10292 10265 12353 -2789 -1806 -630 O ATOM 114 CB THR X 290 1.993 4.730 54.967 1.00 89.89 C ANISOU 114 CB THR X 290 11615 9759 12777 -2957 -1959 -660 C ATOM 115 OG1 THR X 290 1.375 5.047 53.713 1.00 90.84 O ANISOU 115 OG1 THR X 290 11558 10044 12911 -2945 -2205 -900 O ATOM 116 CG2 THR X 290 1.125 3.727 55.734 1.00 93.92 C ANISOU 116 CG2 THR X 290 12103 10063 13519 -3418 -1888 -543 C ATOM 117 N GLU X 291 0.306 6.662 57.151 1.00 88.44 N ANISOU 117 N GLU X 291 10603 10291 12706 -3179 -1416 -298 N ATOM 118 CA GLU X 291 -0.841 7.473 57.552 1.00 89.11 C ANISOU 118 CA GLU X 291 10214 10725 12915 -3302 -1275 -274 C ATOM 119 C GLU X 291 -0.336 8.847 57.987 1.00 85.10 C ANISOU 119 C GLU X 291 9618 10495 12221 -2949 -1111 -204 C ATOM 120 O GLU X 291 0.473 8.953 58.913 1.00 83.28 O ANISOU 120 O GLU X 291 9609 10201 11833 -2843 -917 -40 O ATOM 121 CB GLU X 291 -1.614 6.788 58.685 1.00 92.61 C ANISOU 121 CB GLU X 291 10566 11101 13519 -3721 -1027 -104 C ATOM 122 CG GLU X 291 -2.763 7.606 59.277 1.00 94.12 C ANISOU 122 CG GLU X 291 10251 11667 13844 -3844 -802 -74 C ATOM 123 CD GLU X 291 -4.037 7.523 58.463 1.00 97.68 C ANISOU 123 CD GLU X 291 10265 12264 14583 -4066 -991 -262 C ATOM 124 OE1 GLU X 291 -4.443 8.559 57.899 1.00 96.69 O ANISOU 124 OE1 GLU X 291 9807 12442 14486 -3840 -1099 -391 O ATOM 125 OE2 GLU X 291 -4.632 6.425 58.386 1.00101.65 O ANISOU 125 OE2 GLU X 291 10760 12567 15293 -4468 -1050 -279 O ATOM 126 N GLU X 292 -0.815 9.891 57.314 1.00 83.96 N ANISOU 126 N GLU X 292 9164 10638 12097 -2770 -1214 -331 N ATOM 127 CA GLU X 292 -0.313 11.251 57.522 1.00 80.29 C ANISOU 127 CA GLU X 292 8641 10400 11465 -2416 -1106 -295 C ATOM 128 C GLU X 292 -0.635 11.812 58.908 1.00 80.02 C ANISOU 128 C GLU X 292 8437 10535 11431 -2468 -762 -142 C ATOM 129 O GLU X 292 0.219 12.439 59.536 1.00 77.29 O ANISOU 129 O GLU X 292 8257 10215 10894 -2249 -615 -48 O ATOM 130 CB GLU X 292 -0.826 12.192 56.428 1.00 80.12 C ANISOU 130 CB GLU X 292 8357 10609 11476 -2219 -1324 -455 C ATOM 131 CG GLU X 292 -0.031 13.488 56.293 1.00 76.99 C ANISOU 131 CG GLU X 292 8029 10346 10876 -1825 -1289 -437 C ATOM 132 CD GLU X 292 -0.546 14.393 55.183 1.00 77.91 C ANISOU 132 CD GLU X 292 7937 10655 11007 -1629 -1525 -567 C ATOM 133 OE1 GLU X 292 -0.609 15.622 55.405 1.00 76.87 O ANISOU 133 OE1 GLU X 292 7652 10712 10841 -1403 -1437 -535 O ATOM 134 OE2 GLU X 292 -0.885 13.880 54.092 1.00 79.84 O ANISOU 134 OE2 GLU X 292 8197 10848 11289 -1695 -1813 -701 O ATOM 135 N HIS X 293 -1.860 11.582 59.378 1.00 83.06 N ANISOU 135 N HIS X 293 8488 11041 12028 -2765 -630 -130 N ATOM 136 CA HIS X 293 -2.281 12.055 60.697 1.00 83.50 C ANISOU 136 CA HIS X 293 8374 11275 12077 -2842 -264 -4 C ATOM 137 C HIS X 293 -1.545 11.317 61.814 1.00 83.04 C ANISOU 137 C HIS X 293 8708 10996 11847 -2977 -54 201 C ATOM 138 O HIS X 293 -1.153 11.927 62.812 1.00 81.65 O ANISOU 138 O HIS X 293 8615 10914 11491 -2857 184 310 O ATOM 139 CB HIS X 293 -3.798 11.922 60.866 1.00 87.93 C ANISOU 139 CB HIS X 293 8448 12030 12931 -3146 -153 -55 C ATOM 140 CG HIS X 293 -4.342 12.652 62.057 1.00 89.19 C ANISOU 140 CG HIS X 293 8357 12444 13087 -3160 236 18 C ATOM 141 ND1 HIS X 293 -4.411 14.028 62.120 1.00 87.61 N ANISOU 141 ND1 HIS X 293 7946 12499 12840 -2822 301 -55 N ATOM 142 CD2 HIS X 293 -4.853 12.197 63.226 1.00 92.24 C ANISOU 142 CD2 HIS X 293 8690 12860 13497 -3471 597 152 C ATOM 143 CE1 HIS X 293 -4.934 14.388 63.279 1.00 89.48 C ANISOU 143 CE1 HIS X 293 8004 12917 13075 -2909 684 6 C ATOM 144 NE2 HIS X 293 -5.211 13.296 63.968 1.00 92.32 N ANISOU 144 NE2 HIS X 293 8454 13159 13462 -3306 882 137 N ATOM 145 N LYS X 294 -1.355 10.010 61.631 1.00 84.29 N ANISOU 145 N LYS X 294 9126 10845 12055 -3216 -166 248 N ATOM 146 CA LYS X 294 -0.597 9.188 62.575 1.00 84.25 C ANISOU 146 CA LYS X 294 9547 10570 11891 -3324 -36 456 C ATOM 147 C LYS X 294 0.872 9.606 62.630 1.00 79.98 C ANISOU 147 C LYS X 294 9353 9942 11093 -2943 -119 493 C ATOM 148 O LYS X 294 1.501 9.537 63.687 1.00 79.57 O ANISOU 148 O LYS X 294 9560 9818 10853 -2917 38 669 O ATOM 149 CB LYS X 294 -0.714 7.701 62.229 1.00 87.14 C ANISOU 149 CB LYS X 294 10128 10580 12399 -3637 -183 478 C ATOM 150 N PHE X 295 1.408 10.037 61.489 1.00 77.06 N ANISOU 150 N PHE X 295 8982 9585 10711 -2660 -368 327 N ATOM 151 CA PHE X 295 2.763 10.579 61.420 1.00 73.09 C ANISOU 151 CA PHE X 295 8723 9045 10000 -2298 -434 333 C ATOM 152 C PHE X 295 2.847 11.911 62.159 1.00 71.04 C ANISOU 152 C PHE X 295 8317 9064 9608 -2110 -239 373 C ATOM 153 O PHE X 295 3.783 12.144 62.920 1.00 69.42 O ANISOU 153 O PHE X 295 8338 8817 9218 -1966 -163 478 O ATOM 154 CB PHE X 295 3.214 10.750 59.962 1.00 71.30 C ANISOU 154 CB PHE X 295 8513 8789 9787 -2074 -706 142 C ATOM 155 CG PHE X 295 4.548 11.442 59.810 1.00 67.58 C ANISOU 155 CG PHE X 295 8220 8325 9131 -1715 -742 133 C ATOM 156 CD1 PHE X 295 5.738 10.734 59.959 1.00 66.74 C ANISOU 156 CD1 PHE X 295 8455 7963 8940 -1614 -801 189 C ATOM 157 CD2 PHE X 295 4.613 12.802 59.517 1.00 64.93 C ANISOU 157 CD2 PHE X 295 7699 8241 8728 -1481 -720 69 C ATOM 158 CE1 PHE X 295 6.969 11.369 59.823 1.00 63.69 C ANISOU 158 CE1 PHE X 295 8180 7602 8417 -1303 -825 171 C ATOM 159 CE2 PHE X 295 5.839 13.446 59.381 1.00 61.84 C ANISOU 159 CE2 PHE X 295 7457 7852 8188 -1192 -738 64 C ATOM 160 CZ PHE X 295 7.018 12.728 59.533 1.00 61.35 C ANISOU 160 CZ PHE X 295 7692 7562 8054 -1111 -785 110 C ATOM 161 N GLN X 296 1.859 12.772 61.930 1.00 71.35 N ANISOU 161 N GLN X 296 7979 9376 9755 -2105 -178 276 N ATOM 162 CA GLN X 296 1.844 14.114 62.508 1.00 69.75 C ANISOU 162 CA GLN X 296 7622 9425 9454 -1904 -7 273 C ATOM 163 C GLN X 296 1.604 14.124 64.015 1.00 71.22 C ANISOU 163 C GLN X 296 7843 9679 9535 -2053 309 419 C ATOM 164 O GLN X 296 2.096 15.011 64.711 1.00 69.69 O ANISOU 164 O GLN X 296 7715 9592 9169 -1867 435 445 O ATOM 165 CB GLN X 296 0.823 15.003 61.795 1.00 70.35 C ANISOU 165 CB GLN X 296 7283 9747 9696 -1827 -54 121 C ATOM 166 CG GLN X 296 1.272 15.453 60.410 1.00 68.43 C ANISOU 166 CG GLN X 296 7063 9487 9449 -1577 -346 -7 C ATOM 167 CD GLN X 296 0.325 16.446 59.759 1.00 69.32 C ANISOU 167 CD GLN X 296 6803 9835 9698 -1452 -423 -132 C ATOM 168 OE1 GLN X 296 -0.591 16.967 60.397 1.00 71.18 O ANISOU 168 OE1 GLN X 296 6734 10266 10044 -1497 -240 -139 O ATOM 169 NE2 GLN X 296 0.549 16.717 58.478 1.00 68.33 N ANISOU 169 NE2 GLN X 296 6711 9690 9559 -1279 -696 -231 N ATOM 170 N GLU X 297 0.855 13.142 64.512 1.00 74.46 N ANISOU 170 N GLU X 297 8231 10021 10035 -2401 440 512 N ATOM 171 CA GLU X 297 0.598 13.027 65.948 1.00 76.46 C ANISOU 171 CA GLU X 297 8566 10330 10153 -2583 767 672 C ATOM 172 C GLU X 297 1.785 12.412 66.694 1.00 75.56 C ANISOU 172 C GLU X 297 8948 9972 9790 -2559 743 855 C ATOM 173 O GLU X 297 2.070 12.793 67.829 1.00 75.83 O ANISOU 173 O GLU X 297 9136 10081 9593 -2527 941 961 O ATOM 174 CB GLU X 297 -0.703 12.254 66.229 1.00 80.96 C ANISOU 174 CB GLU X 297 8908 10934 10916 -2995 958 718 C ATOM 175 CG GLU X 297 -0.644 10.746 65.979 1.00 83.20 C ANISOU 175 CG GLU X 297 9431 10888 11292 -3293 826 821 C ATOM 176 CD GLU X 297 -1.973 10.044 66.225 1.00 88.32 C ANISOU 176 CD GLU X 297 9816 11575 12165 -3739 1023 858 C ATOM 177 OE1 GLU X 297 -2.012 9.131 67.078 1.00 91.23 O ANISOU 177 OE1 GLU X 297 10443 11762 12455 -4040 1200 1064 O ATOM 178 OE2 GLU X 297 -2.976 10.399 65.568 1.00 89.65 O ANISOU 178 OE2 GLU X 297 9517 11949 12594 -3796 995 689 O ATOM 179 N GLN X 298 2.472 11.473 66.045 1.00 74.77 N ANISOU 179 N GLN X 298 9098 9578 9733 -2558 485 878 N ATOM 180 CA GLN X 298 3.598 10.766 66.653 1.00 74.38 C ANISOU 180 CA GLN X 298 9503 9261 9495 -2514 410 1047 C ATOM 181 C GLN X 298 4.856 11.630 66.685 1.00 70.65 C ANISOU 181 C GLN X 298 9160 8837 8847 -2136 293 1004 C ATOM 182 O GLN X 298 5.623 11.585 67.648 1.00 70.70 O ANISOU 182 O GLN X 298 9449 8777 8636 -2070 322 1145 O ATOM 183 CB GLN X 298 3.865 9.451 65.919 1.00 75.47 C ANISOU 183 CB GLN X 298 9847 9051 9776 -2623 178 1060 C ATOM 184 CG GLN X 298 4.618 8.423 66.745 1.00 77.36 C ANISOU 184 CG GLN X 298 10544 8974 9875 -2691 146 1283 C ATOM 185 CD GLN X 298 4.282 7.001 66.345 1.00 80.60 C ANISOU 185 CD GLN X 298 11118 9040 10466 -2964 39 1334 C ATOM 186 N VAL X 299 5.057 12.407 65.623 1.00 67.75 N ANISOU 186 N VAL X 299 8589 8580 8571 -1902 151 815 N ATOM 187 CA VAL X 299 6.129 13.399 65.558 1.00 64.43 C ANISOU 187 CA VAL X 299 8218 8239 8021 -1572 71 753 C ATOM 188 C VAL X 299 5.860 14.498 66.584 1.00 64.25 C ANISOU 188 C VAL X 299 8103 8461 7847 -1530 297 771 C ATOM 189 O VAL X 299 6.761 14.906 67.321 1.00 63.23 O ANISOU 189 O VAL X 299 8167 8331 7525 -1388 295 825 O ATOM 190 CB VAL X 299 6.267 13.981 64.122 1.00 62.13 C ANISOU 190 CB VAL X 299 7738 8008 7859 -1372 -101 561 C ATOM 191 CG1 VAL X 299 6.992 15.318 64.119 1.00 59.40 C ANISOU 191 CG1 VAL X 299 7345 7816 7408 -1090 -100 493 C ATOM 192 CG2 VAL X 299 6.980 12.989 63.213 1.00 61.97 C ANISOU 192 CG2 VAL X 299 7906 7730 7908 -1327 -329 527 C ATOM 193 N SER X 300 4.608 14.949 66.633 1.00 65.61 N ANISOU 193 N SER X 300 7972 8839 8117 -1653 484 710 N ATOM 194 CA SER X 300 4.150 15.923 67.619 1.00 66.31 C ANISOU 194 CA SER X 300 7953 9162 8080 -1632 744 700 C ATOM 195 C SER X 300 4.399 15.441 69.048 1.00 68.30 C ANISOU 195 C SER X 300 8510 9361 8079 -1778 915 884 C ATOM 196 O SER X 300 4.800 16.223 69.907 1.00 67.93 O ANISOU 196 O SER X 300 8571 9421 7815 -1655 1017 884 O ATOM 197 CB SER X 300 2.665 16.228 67.409 1.00 68.41 C ANISOU 197 CB SER X 300 7813 9637 8543 -1766 924 606 C ATOM 198 OG SER X 300 2.192 17.186 68.337 1.00 69.74 O ANISOU 198 OG SER X 300 7861 10031 8603 -1718 1200 567 O ATOM 199 N LYS X 301 4.171 14.151 69.290 1.00 70.69 N ANISOU 199 N LYS X 301 8980 9482 8397 -2044 932 1041 N ATOM 200 CA LYS X 301 4.399 13.556 70.606 1.00 73.16 C ANISOU 200 CA LYS X 301 9642 9707 8446 -2203 1072 1256 C ATOM 201 C LYS X 301 5.888 13.398 70.909 1.00 71.44 C ANISOU 201 C LYS X 301 9804 9305 8036 -1993 826 1342 C ATOM 202 O LYS X 301 6.324 13.649 72.034 1.00 72.38 O ANISOU 202 O LYS X 301 10168 9464 7866 -1961 902 1441 O ATOM 203 CB LYS X 301 3.688 12.203 70.727 1.00 76.69 C ANISOU 203 CB LYS X 301 10172 9976 8987 -2570 1158 1417 C ATOM 204 N GLU X 302 6.657 12.991 69.901 1.00 69.26 N ANISOU 204 N GLU X 302 9561 8836 7915 -1844 530 1289 N ATOM 205 CA GLU X 302 8.088 12.737 70.064 1.00 67.98 C ANISOU 205 CA GLU X 302 9701 8490 7637 -1632 277 1354 C ATOM 206 C GLU X 302 8.904 14.010 70.280 1.00 65.42 C ANISOU 206 C GLU X 302 9330 8339 7185 -1356 225 1242 C ATOM 207 O GLU X 302 9.911 13.986 70.988 1.00 65.56 O ANISOU 207 O GLU X 302 9602 8285 7019 -1237 95 1326 O ATOM 208 CB GLU X 302 8.641 11.959 68.867 1.00 66.83 C ANISOU 208 CB GLU X 302 9571 8105 7714 -1541 15 1296 C ATOM 209 N LEU X 303 8.465 15.115 69.683 1.00 63.43 N ANISOU 209 N LEU X 303 8761 8300 7038 -1260 307 1056 N ATOM 210 CA LEU X 303 9.249 16.354 69.691 1.00 61.03 C ANISOU 210 CA LEU X 303 8402 8122 6664 -1008 241 931 C ATOM 211 C LEU X 303 8.870 17.362 70.773 1.00 61.97 C ANISOU 211 C LEU X 303 8517 8452 6575 -1013 456 901 C ATOM 212 O LEU X 303 9.753 17.977 71.371 1.00 61.43 O ANISOU 212 O LEU X 303 8592 8408 6337 -872 375 881 O ATOM 213 CB LEU X 303 9.220 17.028 68.316 1.00 58.37 C ANISOU 213 CB LEU X 303 7782 7842 6550 -857 159 751 C ATOM 214 CG LEU X 303 10.000 16.349 67.188 1.00 56.93 C ANISOU 214 CG LEU X 303 7634 7474 6523 -758 -76 725 C ATOM 215 CD1 LEU X 303 9.706 17.038 65.878 1.00 54.88 C ANISOU 215 CD1 LEU X 303 7116 7303 6431 -652 -108 562 C ATOM 216 CD2 LEU X 303 11.500 16.340 67.461 1.00 56.07 C ANISOU 216 CD2 LEU X 303 7712 7261 6330 -575 -259 752 C ATOM 217 N ILE X 304 7.572 17.543 71.012 1.00 63.69 N ANISOU 217 N ILE X 304 8559 8824 6815 -1171 728 878 N ATOM 218 CA ILE X 304 7.108 18.526 71.995 1.00 64.96 C ANISOU 218 CA ILE X 304 8698 9195 6788 -1160 974 813 C ATOM 219 C ILE X 304 7.660 18.209 73.384 1.00 67.13 C ANISOU 219 C ILE X 304 9359 9435 6710 -1225 1006 959 C ATOM 220 O ILE X 304 7.346 17.169 73.968 1.00 69.85 O ANISOU 220 O ILE X 304 9900 9697 6940 -1443 1094 1146 O ATOM 221 CB ILE X 304 5.561 18.669 72.010 1.00 67.09 C ANISOU 221 CB ILE X 304 8670 9646 7173 -1320 1288 757 C ATOM 222 CG1 ILE X 304 5.085 19.391 70.744 1.00 65.03 C ANISOU 222 CG1 ILE X 304 8027 9462 7217 -1175 1220 576 C ATOM 223 CG2 ILE X 304 5.091 19.427 73.258 1.00 69.39 C ANISOU 223 CG2 ILE X 304 9010 10137 7216 -1337 1596 712 C ATOM 224 CD1 ILE X 304 3.584 19.320 70.503 1.00 67.06 C ANISOU 224 CD1 ILE X 304 7927 9874 7677 -1326 1443 521 C ATOM 225 N GLY X 305 8.502 19.109 73.886 1.00 66.25 N ANISOU 225 N GLY X 305 9375 9373 6424 -1043 913 876 N ATOM 226 CA GLY X 305 9.151 18.936 75.182 1.00 68.32 C ANISOU 226 CA GLY X 305 10023 9612 6324 -1068 876 991 C ATOM 227 C GLY X 305 10.656 18.752 75.092 1.00 66.83 C ANISOU 227 C GLY X 305 10022 9260 6109 -903 494 1030 C ATOM 228 O GLY X 305 11.324 18.556 76.111 1.00 68.70 O ANISOU 228 O GLY X 305 10585 9460 6056 -899 381 1132 O ATOM 229 N LEU X 306 11.191 18.813 73.873 1.00 63.79 N ANISOU 229 N LEU X 306 9427 8787 6022 -764 294 948 N ATOM 230 CA LEU X 306 12.629 18.672 73.655 1.00 62.48 C ANISOU 230 CA LEU X 306 9359 8485 5895 -594 -44 957 C ATOM 231 C LEU X 306 13.301 20.020 73.435 1.00 60.52 C ANISOU 231 C LEU X 306 8967 8333 5692 -415 -126 759 C ATOM 232 O LEU X 306 12.719 20.931 72.843 1.00 59.12 O ANISOU 232 O LEU X 306 8550 8262 5651 -379 21 609 O ATOM 233 CB LEU X 306 12.926 17.751 72.465 1.00 61.06 C ANISOU 233 CB LEU X 306 9074 8125 5999 -559 -202 997 C ATOM 234 CG LEU X 306 12.424 16.303 72.437 1.00 62.89 C ANISOU 234 CG LEU X 306 9448 8184 6261 -729 -183 1181 C ATOM 235 CD1 LEU X 306 12.817 15.668 71.114 1.00 61.17 C ANISOU 235 CD1 LEU X 306 9099 7801 6339 -643 -350 1139 C ATOM 236 CD2 LEU X 306 12.948 15.473 73.604 1.00 65.67 C ANISOU 236 CD2 LEU X 306 10190 8404 6357 -777 -305 1394 C ATOM 237 N VAL X 307 14.532 20.133 73.925 1.00 60.84 N ANISOU 237 N VAL X 307 9159 8323 5632 -307 -380 764 N ATOM 238 CA VAL X 307 15.365 21.305 73.695 1.00 59.30 C ANISOU 238 CA VAL X 307 8836 8182 5513 -162 -502 587 C ATOM 239 C VAL X 307 16.086 21.134 72.364 1.00 56.92 C ANISOU 239 C VAL X 307 8311 7784 5533 -48 -652 545 C ATOM 240 O VAL X 307 16.631 20.066 72.076 1.00 57.32 O ANISOU 240 O VAL X 307 8410 7698 5668 -15 -815 652 O ATOM 241 CB VAL X 307 16.375 21.525 74.856 1.00 61.20 C ANISOU 241 CB VAL X 307 9315 8429 5507 -117 -727 593 C ATOM 242 CG1 VAL X 307 17.558 22.381 74.419 1.00 59.96 C ANISOU 242 CG1 VAL X 307 8994 8267 5521 18 -941 440 C ATOM 243 CG2 VAL X 307 15.679 22.157 76.048 1.00 63.38 C ANISOU 243 CG2 VAL X 307 9788 8842 5450 -205 -537 549 C ATOM 244 N VAL X 308 16.065 22.181 71.547 1.00 54.87 N ANISOU 244 N VAL X 308 7822 7582 5442 16 -583 389 N ATOM 245 CA VAL X 308 16.749 22.164 70.258 1.00 52.81 C ANISOU 245 CA VAL X 308 7361 7252 5451 116 -683 339 C ATOM 246 C VAL X 308 17.793 23.272 70.174 1.00 52.25 C ANISOU 246 C VAL X 308 7195 7207 5448 203 -793 209 C ATOM 247 O VAL X 308 17.590 24.368 70.701 1.00 52.56 O ANISOU 247 O VAL X 308 7256 7321 5393 185 -723 109 O ATOM 248 CB VAL X 308 15.758 22.265 69.067 1.00 51.18 C ANISOU 248 CB VAL X 308 6969 7064 5410 98 -507 301 C ATOM 249 CG1 VAL X 308 14.936 20.991 68.953 1.00 51.96 C ANISOU 249 CG1 VAL X 308 7127 7104 5510 -3 -451 423 C ATOM 250 CG2 VAL X 308 14.850 23.488 69.196 1.00 50.84 C ANISOU 250 CG2 VAL X 308 6846 7141 5330 83 -316 196 C ATOM 251 N LEU X 309 18.914 22.972 69.524 1.00 51.75 N ANISOU 251 N LEU X 309 7024 7075 5560 290 -956 199 N ATOM 252 CA LEU X 309 19.959 23.964 69.293 1.00 51.45 C ANISOU 252 CA LEU X 309 6849 7058 5641 342 -1044 79 C ATOM 253 C LEU X 309 19.964 24.408 67.836 1.00 49.63 C ANISOU 253 C LEU X 309 6414 6817 5626 376 -923 18 C ATOM 254 O LEU X 309 20.071 23.583 66.928 1.00 49.15 O ANISOU 254 O LEU X 309 6284 6704 5685 423 -918 58 O ATOM 255 CB LEU X 309 21.335 23.416 69.694 1.00 52.92 C ANISOU 255 CB LEU X 309 7026 7201 5878 415 -1314 99 C ATOM 256 CG LEU X 309 22.604 24.103 69.163 1.00 52.96 C ANISOU 256 CG LEU X 309 6804 7217 6100 464 -1411 -14 C ATOM 257 CD1 LEU X 309 22.754 25.529 69.683 1.00 53.16 C ANISOU 257 CD1 LEU X 309 6824 7298 6075 388 -1407 -137 C ATOM 258 CD2 LEU X 309 23.836 23.274 69.503 1.00 55.04 C ANISOU 258 CD2 LEU X 309 7018 7442 6451 566 -1684 16 C ATOM 259 N THR X 310 19.851 25.715 67.625 1.00 49.03 N ANISOU 259 N THR X 310 6273 6773 5581 353 -829 -79 N ATOM 260 CA THR X 310 19.932 26.285 66.286 1.00 47.80 C ANISOU 260 CA THR X 310 5966 6599 5597 377 -722 -120 C ATOM 261 C THR X 310 21.385 26.333 65.824 1.00 48.23 C ANISOU 261 C THR X 310 5875 6630 5819 406 -822 -158 C ATOM 262 O THR X 310 22.274 26.718 66.584 1.00 49.54 O ANISOU 262 O THR X 310 6020 6804 5996 384 -960 -211 O ATOM 263 CB THR X 310 19.299 27.693 66.219 1.00 47.57 C ANISOU 263 CB THR X 310 5943 6576 5551 350 -594 -194 C ATOM 264 OG1 THR X 310 19.761 28.489 67.318 1.00 48.98 O ANISOU 264 OG1 THR X 310 6195 6758 5657 309 -674 -276 O ATOM 265 CG2 THR X 310 17.779 27.595 66.275 1.00 47.13 C ANISOU 265 CG2 THR X 310 5945 6559 5401 352 -457 -165 C ATOM 266 N LYS X 311 21.618 25.929 64.579 1.00 47.53 N ANISOU 266 N LYS X 311 5679 6522 5858 453 -750 -144 N ATOM 267 CA LYS X 311 22.969 25.846 64.019 1.00 48.31 C ANISOU 267 CA LYS X 311 5605 6617 6133 488 -792 -187 C ATOM 268 C LYS X 311 23.582 27.210 63.688 1.00 48.61 C ANISOU 268 C LYS X 311 5535 6660 6274 411 -720 -257 C ATOM 269 O LYS X 311 24.805 27.338 63.577 1.00 49.84 O ANISOU 269 O LYS X 311 5518 6830 6586 400 -769 -308 O ATOM 270 CB LYS X 311 22.975 24.962 62.768 1.00 47.91 C ANISOU 270 CB LYS X 311 5503 6546 6154 564 -702 -167 C ATOM 271 CG LYS X 311 21.888 25.291 61.744 1.00 46.87 C ANISOU 271 CG LYS X 311 5439 6413 5957 544 -533 -145 C ATOM 272 CD LYS X 311 22.265 24.821 60.345 1.00 47.68 C ANISOU 272 CD LYS X 311 5478 6509 6129 602 -430 -166 C ATOM 273 CE LYS X 311 22.314 23.302 60.234 1.00 48.33 C ANISOU 273 CE LYS X 311 5591 6545 6226 692 -505 -162 C ATOM 274 NZ LYS X 311 22.856 22.876 58.915 1.00 49.20 N ANISOU 274 NZ LYS X 311 5642 6651 6399 765 -393 -221 N ATOM 275 N TYR X 312 22.725 28.216 63.537 1.00 47.73 N ANISOU 275 N TYR X 312 5516 6526 6091 357 -605 -259 N ATOM 276 CA TYR X 312 23.122 29.540 63.059 1.00 48.09 C ANISOU 276 CA TYR X 312 5512 6528 6229 275 -511 -301 C ATOM 277 C TYR X 312 23.293 30.566 64.182 1.00 49.04 C ANISOU 277 C TYR X 312 5688 6615 6330 191 -603 -381 C ATOM 278 O TYR X 312 23.764 31.680 63.950 1.00 49.90 O ANISOU 278 O TYR X 312 5763 6657 6539 98 -556 -427 O ATOM 279 CB TYR X 312 22.102 30.047 62.034 1.00 47.10 C ANISOU 279 CB TYR X 312 5476 6364 6053 294 -346 -248 C ATOM 280 CG TYR X 312 20.673 29.965 62.522 1.00 46.31 C ANISOU 280 CG TYR X 312 5511 6273 5809 343 -346 -229 C ATOM 281 CD1 TYR X 312 20.105 31.011 63.243 1.00 46.81 C ANISOU 281 CD1 TYR X 312 5667 6293 5823 322 -337 -278 C ATOM 282 CD2 TYR X 312 19.894 28.836 62.275 1.00 45.57 C ANISOU 282 CD2 TYR X 312 5442 6228 5645 405 -345 -175 C ATOM 283 CE1 TYR X 312 18.803 30.941 63.700 1.00 46.56 C ANISOU 283 CE1 TYR X 312 5718 6291 5680 376 -305 -277 C ATOM 284 CE2 TYR X 312 18.585 28.756 62.731 1.00 45.35 C ANISOU 284 CE2 TYR X 312 5491 6225 5514 427 -325 -161 C ATOM 285 CZ TYR X 312 18.047 29.811 63.443 1.00 45.85 C ANISOU 285 CZ TYR X 312 5615 6270 5535 419 -293 -213 C ATOM 286 OH TYR X 312 16.749 29.741 63.894 1.00 45.88 O ANISOU 286 OH TYR X 312 5657 6320 5456 449 -240 -215 O ATOM 287 N ASN X 313 22.895 30.185 65.393 1.00 49.16 N ANISOU 287 N ASN X 313 5814 6663 6201 214 -728 -398 N ATOM 288 CA ASN X 313 23.003 31.043 66.569 1.00 50.38 C ANISOU 288 CA ASN X 313 6065 6794 6283 146 -829 -497 C ATOM 289 C ASN X 313 23.053 30.150 67.801 1.00 51.08 C ANISOU 289 C ASN X 313 6245 6951 6210 178 -1009 -489 C ATOM 290 O ASN X 313 22.246 29.228 67.927 1.00 50.27 O ANISOU 290 O ASN X 313 6232 6887 5979 241 -971 -403 O ATOM 291 CB ASN X 313 21.804 31.999 66.644 1.00 50.05 C ANISOU 291 CB ASN X 313 6177 6695 6145 153 -689 -529 C ATOM 292 CG ASN X 313 22.076 33.235 67.495 1.00 51.90 C ANISOU 292 CG ASN X 313 6504 6851 6362 72 -753 -668 C ATOM 293 OD1 ASN X 313 23.063 33.304 68.229 1.00 53.76 O ANISOU 293 OD1 ASN X 313 6711 7098 6615 -2 -931 -744 O ATOM 294 ND2 ASN X 313 21.189 34.220 67.397 1.00 51.94 N ANISOU 294 ND2 ASN X 313 6624 6768 6341 96 -624 -713 N ATOM 295 N ASN X 314 23.994 30.420 68.706 1.00 52.87 N ANISOU 295 N ASN X 314 6461 7187 6438 123 -1215 -573 N ATOM 296 CA ASN X 314 24.204 29.566 69.883 1.00 54.09 C ANISOU 296 CA ASN X 314 6728 7402 6421 160 -1432 -550 C ATOM 297 C ASN X 314 23.094 29.658 70.942 1.00 54.31 C ANISOU 297 C ASN X 314 7036 7455 6144 156 -1387 -556 C ATOM 298 O ASN X 314 23.355 29.889 72.124 1.00 56.29 O ANISOU 298 O ASN X 314 7439 7730 6217 120 -1554 -627 O ATOM 299 CB ASN X 314 25.601 29.787 70.493 1.00 56.52 C ANISOU 299 CB ASN X 314 6921 7725 6826 112 -1713 -642 C ATOM 300 CG ASN X 314 25.799 31.195 71.034 1.00 58.15 C ANISOU 300 CG ASN X 314 7187 7887 7021 -14 -1756 -804 C ATOM 301 OD1 ASN X 314 25.682 32.183 70.306 1.00 57.92 O ANISOU 301 OD1 ASN X 314 7094 7779 7133 -86 -1583 -857 O ATOM 302 ND2 ASN X 314 26.114 31.289 72.322 1.00 60.38 N ANISOU 302 ND2 ASN X 314 7619 8201 7122 -44 -2001 -885 N ATOM 303 N LYS X 315 21.856 29.458 70.498 1.00 52.62 N ANISOU 303 N LYS X 315 6881 7245 5867 191 -1156 -488 N ATOM 304 CA LYS X 315 20.680 29.554 71.359 1.00 53.10 C ANISOU 304 CA LYS X 315 7157 7347 5671 187 -1038 -499 C ATOM 305 C LYS X 315 19.875 28.256 71.366 1.00 52.42 C ANISOU 305 C LYS X 315 7133 7307 5478 216 -959 -344 C ATOM 306 O LYS X 315 19.809 27.549 70.360 1.00 50.89 O ANISOU 306 O LYS X 315 6807 7089 5439 251 -915 -252 O ATOM 307 CB LYS X 315 19.793 30.725 70.922 1.00 52.44 C ANISOU 307 CB LYS X 315 7065 7223 5635 193 -818 -591 C ATOM 308 CG LYS X 315 20.409 32.094 71.163 1.00 53.94 C ANISOU 308 CG LYS X 315 7275 7330 5888 143 -883 -756 C ATOM 309 CD LYS X 315 19.509 33.210 70.657 1.00 54.27 C ANISOU 309 CD LYS X 315 7327 7291 5999 180 -677 -830 C ATOM 310 CE LYS X 315 20.011 34.582 71.104 1.00 56.43 C ANISOU 310 CE LYS X 315 7688 7446 6306 121 -741 -1010 C ATOM 311 NZ LYS X 315 21.323 34.958 70.492 1.00 56.82 N ANISOU 311 NZ LYS X 315 7590 7409 6587 22 -877 -1017 N ATOM 312 N THR X 316 19.266 27.955 72.510 1.00 53.90 N ANISOU 312 N THR X 316 7538 7552 5389 186 -933 -321 N ATOM 313 CA THR X 316 18.430 26.763 72.663 1.00 53.92 C ANISOU 313 CA THR X 316 7627 7585 5272 169 -836 -166 C ATOM 314 C THR X 316 16.979 27.109 72.992 1.00 54.30 C ANISOU 314 C THR X 316 7741 7706 5182 134 -553 -196 C ATOM 315 O THR X 316 16.701 28.083 73.698 1.00 55.54 O ANISOU 315 O THR X 316 7996 7904 5201 130 -474 -332 O ATOM 316 CB THR X 316 18.980 25.806 73.737 1.00 56.03 C ANISOU 316 CB THR X 316 8112 7855 5322 150 -1043 -57 C ATOM 317 OG1 THR X 316 19.394 26.556 74.886 1.00 57.93 O ANISOU 317 OG1 THR X 316 8530 8140 5341 126 -1160 -168 O ATOM 318 CG2 THR X 316 20.160 25.019 73.193 1.00 55.71 C ANISOU 318 CG2 THR X 316 7952 7737 5478 219 -1291 16 C ATOM 319 N TYR X 317 16.062 26.299 72.472 1.00 53.52 N ANISOU 319 N TYR X 317 7575 7622 5137 110 -402 -86 N ATOM 320 CA TYR X 317 14.633 26.536 72.636 1.00 54.15 C ANISOU 320 CA TYR X 317 7634 7787 5151 76 -121 -113 C ATOM 321 C TYR X 317 13.908 25.244 72.984 1.00 55.21 C ANISOU 321 C TYR X 317 7850 7952 5172 -29 -24 50 C ATOM 322 O TYR X 317 14.287 24.167 72.519 1.00 54.63 O ANISOU 322 O TYR X 317 7773 7796 5186 -51 -152 184 O ATOM 323 CB TYR X 317 14.035 27.121 71.352 1.00 52.35 C ANISOU 323 CB TYR X 317 7155 7546 5189 144 -13 -174 C ATOM 324 CG TYR X 317 14.786 28.305 70.782 1.00 51.65 C ANISOU 324 CG TYR X 317 6991 7385 5248 229 -105 -296 C ATOM 325 CD1 TYR X 317 15.858 28.122 69.907 1.00 50.59 C ANISOU 325 CD1 TYR X 317 6769 7167 5283 252 -278 -258 C ATOM 326 CD2 TYR X 317 14.420 29.609 71.109 1.00 52.80 C ANISOU 326 CD2 TYR X 317 7156 7533 5371 282 -2 -452 C ATOM 327 CE1 TYR X 317 16.553 29.207 69.381 1.00 50.31 C ANISOU 327 CE1 TYR X 317 6666 7061 5386 293 -334 -353 C ATOM 328 CE2 TYR X 317 15.106 30.702 70.586 1.00 52.45 C ANISOU 328 CE2 TYR X 317 7068 7386 5472 333 -85 -548 C ATOM 329 CZ TYR X 317 16.171 30.494 69.724 1.00 51.24 C ANISOU 329 CZ TYR X 317 6827 7159 5481 322 -244 -489 C ATOM 330 OH TYR X 317 16.854 31.569 69.203 1.00 51.49 O ANISOU 330 OH TYR X 317 6818 7086 5659 338 -298 -568 O ATOM 331 N ARG X 318 12.865 25.360 73.800 1.00 57.09 N ANISOU 331 N ARG X 318 8166 8298 5224 -99 216 34 N ATOM 332 CA ARG X 318 11.996 24.232 74.105 1.00 58.53 C ANISOU 332 CA ARG X 318 8402 8516 5318 -240 372 189 C ATOM 333 C ARG X 318 10.900 24.141 73.048 1.00 57.41 C ANISOU 333 C ARG X 318 7963 8406 5441 -256 537 174 C ATOM 334 O ARG X 318 10.301 25.154 72.682 1.00 56.98 O ANISOU 334 O ARG X 318 7723 8423 5504 -168 665 25 O ATOM 335 CB ARG X 318 11.380 24.397 75.496 1.00 61.72 C ANISOU 335 CB ARG X 318 9020 9044 5385 -328 593 176 C ATOM 336 CG ARG X 318 10.606 23.184 75.995 1.00 64.27 C ANISOU 336 CG ARG X 318 9457 9394 5570 -518 766 368 C ATOM 337 CD ARG X 318 9.856 23.503 77.278 1.00 68.33 C ANISOU 337 CD ARG X 318 10149 10065 5749 -606 1067 330 C ATOM 338 NE ARG X 318 9.118 22.350 77.792 1.00 71.56 N ANISOU 338 NE ARG X 318 10681 10495 6011 -824 1266 534 N ATOM 339 CZ ARG X 318 7.880 22.017 77.430 1.00 72.66 C ANISOU 339 CZ ARG X 318 10575 10715 6316 -951 1555 555 C ATOM 340 NH1 ARG X 318 7.303 20.949 77.964 1.00 75.54 N ANISOU 340 NH1 ARG X 318 11081 11080 6539 -1185 1734 755 N ATOM 341 NH2 ARG X 318 7.215 22.744 76.537 1.00 70.93 N ANISOU 341 NH2 ARG X 318 9971 10569 6409 -851 1653 384 N ATOM 342 N VAL X 319 10.647 22.932 72.554 1.00 57.26 N ANISOU 342 N VAL X 319 7910 8322 5522 -360 509 322 N ATOM 343 CA VAL X 319 9.568 22.714 71.589 1.00 56.76 C ANISOU 343 CA VAL X 319 7573 8294 5699 -403 632 308 C ATOM 344 C VAL X 319 8.218 22.683 72.310 1.00 59.45 C ANISOU 344 C VAL X 319 7846 8786 5954 -538 953 306 C ATOM 345 O VAL X 319 7.872 21.700 72.970 1.00 61.52 O ANISOU 345 O VAL X 319 8249 9043 6081 -725 1058 452 O ATOM 346 CB VAL X 319 9.784 21.434 70.733 1.00 55.92 C ANISOU 346 CB VAL X 319 7455 8042 5747 -475 473 436 C ATOM 347 CG1 VAL X 319 8.600 21.201 69.793 1.00 55.91 C ANISOU 347 CG1 VAL X 319 7178 8089 5977 -544 577 406 C ATOM 348 CG2 VAL X 319 11.074 21.542 69.932 1.00 53.49 C ANISOU 348 CG2 VAL X 319 7162 7612 5547 -321 204 408 C ATOM 349 N ASP X 320 7.477 23.782 72.187 1.00 59.73 N ANISOU 349 N ASP X 320 7669 8949 6075 -437 1117 140 N ATOM 350 CA ASP X 320 6.154 23.912 72.793 1.00 62.68 C ANISOU 350 CA ASP X 320 7902 9496 6415 -527 1454 93 C ATOM 351 C ASP X 320 5.066 23.312 71.908 1.00 63.12 C ANISOU 351 C ASP X 320 7636 9595 6752 -629 1521 121 C ATOM 352 O ASP X 320 4.081 22.771 72.412 1.00 65.90 O ANISOU 352 O ASP X 320 7896 10056 7086 -814 1774 169 O ATOM 353 CB ASP X 320 5.836 25.381 73.084 1.00 63.25 C ANISOU 353 CB ASP X 320 7879 9673 6476 -339 1594 -121 C ATOM 354 CG ASP X 320 6.488 25.877 74.358 1.00 64.76 C ANISOU 354 CG ASP X 320 8398 9880 6325 -314 1642 -172 C ATOM 355 OD1 ASP X 320 5.936 25.621 75.449 1.00 68.02 O ANISOU 355 OD1 ASP X 320 8933 10414 6497 -437 1907 -152 O ATOM 356 OD2 ASP X 320 7.546 26.535 74.269 1.00 63.27 O ANISOU 356 OD2 ASP X 320 8349 9587 6102 -184 1418 -237 O ATOM 357 N ASP X 321 5.251 23.414 70.592 1.00 60.75 N ANISOU 357 N ASP X 321 7166 9212 6701 -521 1294 89 N ATOM 358 CA ASP X 321 4.263 22.939 69.624 1.00 61.21 C ANISOU 358 CA ASP X 321 6915 9308 7032 -595 1290 87 C ATOM 359 C ASP X 321 4.865 22.808 68.225 1.00 58.32 C ANISOU 359 C ASP X 321 6516 8804 6836 -494 979 89 C ATOM 360 O ASP X 321 5.938 23.352 67.945 1.00 56.00 O ANISOU 360 O ASP X 321 6372 8417 6488 -336 812 65 O ATOM 361 CB ASP X 321 3.051 23.887 69.589 1.00 63.05 C ANISOU 361 CB ASP X 321 6809 9728 7419 -495 1490 -70 C ATOM 362 CG ASP X 321 1.751 23.176 69.228 1.00 65.62 C ANISOU 362 CG ASP X 321 6804 10161 7967 -674 1602 -56 C ATOM 363 OD1 ASP X 321 1.725 22.405 68.243 1.00 64.94 O ANISOU 363 OD1 ASP X 321 6646 9985 8042 -758 1394 1 O ATOM 364 OD2 ASP X 321 0.744 23.400 69.932 1.00 68.99 O ANISOU 364 OD2 ASP X 321 7032 10768 8412 -733 1905 -119 O ATOM 365 N ILE X 322 4.169 22.071 67.360 1.00 58.75 N ANISOU 365 N ILE X 322 6379 8854 7090 -602 912 110 N ATOM 366 CA ILE X 322 4.506 21.985 65.941 1.00 56.72 C ANISOU 366 CA ILE X 322 6068 8499 6984 -505 643 84 C ATOM 367 C ILE X 322 3.340 22.516 65.098 1.00 57.70 C ANISOU 367 C ILE X 322 5838 8748 7336 -435 626 -24 C ATOM 368 O ILE X 322 2.231 21.972 65.137 1.00 60.05 O ANISOU 368 O ILE X 322 5904 9142 7771 -600 720 -29 O ATOM 369 CB ILE X 322 4.878 20.541 65.516 1.00 56.56 C ANISOU 369 CB ILE X 322 6191 8318 6981 -677 497 191 C ATOM 370 CG1 ILE X 322 6.041 20.016 66.366 1.00 55.98 C ANISOU 370 CG1 ILE X 322 6460 8110 6698 -710 480 306 C ATOM 371 CG2 ILE X 322 5.233 20.492 64.026 1.00 54.86 C ANISOU 371 CG2 ILE X 322 5943 8015 6885 -565 241 136 C ATOM 372 CD1 ILE X 322 6.239 18.517 66.301 1.00 56.94 C ANISOU 372 CD1 ILE X 322 6747 8056 6830 -896 393 428 C ATOM 373 N ASP X 323 3.605 23.586 64.350 1.00 56.15 N ANISOU 373 N ASP X 323 5602 8546 7187 -196 497 -105 N ATOM 374 CA ASP X 323 2.598 24.230 63.510 1.00 57.22 C ANISOU 374 CA ASP X 323 5434 8782 7525 -71 427 -200 C ATOM 375 C ASP X 323 2.679 23.696 62.082 1.00 56.33 C ANISOU 375 C ASP X 323 5312 8591 7499 -75 147 -188 C ATOM 376 O ASP X 323 3.551 24.094 61.307 1.00 54.32 O ANISOU 376 O ASP X 323 5232 8232 7175 66 -15 -180 O ATOM 377 CB ASP X 323 2.778 25.755 63.534 1.00 56.69 C ANISOU 377 CB ASP X 323 5368 8725 7447 200 443 -282 C ATOM 378 CG ASP X 323 1.543 26.509 63.050 1.00 58.90 C ANISOU 378 CG ASP X 323 5308 9127 7943 353 424 -384 C ATOM 379 OD1 ASP X 323 0.788 25.980 62.205 1.00 60.06 O ANISOU 379 OD1 ASP X 323 5239 9327 8250 297 277 -390 O ATOM 380 OD2 ASP X 323 1.332 27.649 63.516 1.00 59.70 O ANISOU 380 OD2 ASP X 323 5358 9261 8062 543 538 -469 O ATOM 381 N TRP X 324 1.758 22.795 61.745 1.00 58.19 N ANISOU 381 N TRP X 324 5348 8881 7879 -254 103 -195 N ATOM 382 CA TRP X 324 1.746 22.133 60.439 1.00 57.91 C ANISOU 382 CA TRP X 324 5323 8772 7908 -293 -168 -206 C ATOM 383 C TRP X 324 1.137 23.005 59.342 1.00 58.57 C ANISOU 383 C TRP X 324 5214 8932 8106 -88 -369 -287 C ATOM 384 O TRP X 324 1.293 22.713 58.156 1.00 58.19 O ANISOU 384 O TRP X 324 5241 8822 8046 -61 -619 -302 O ATOM 385 CB TRP X 324 1.006 20.796 60.524 1.00 60.10 C ANISOU 385 CB TRP X 324 5480 9052 8304 -593 -161 -191 C ATOM 386 CG TRP X 324 1.611 19.843 61.513 1.00 59.76 C ANISOU 386 CG TRP X 324 5677 8891 8136 -796 -1 -81 C ATOM 387 CD1 TRP X 324 1.288 19.720 62.833 1.00 61.18 C ANISOU 387 CD1 TRP X 324 5829 9139 8277 -936 280 -21 C ATOM 388 CD2 TRP X 324 2.646 18.885 61.262 1.00 58.29 C ANISOU 388 CD2 TRP X 324 5815 8493 7839 -863 -117 -15 C ATOM 389 NE1 TRP X 324 2.055 18.743 63.421 1.00 60.77 N ANISOU 389 NE1 TRP X 324 6084 8920 8083 -1091 319 99 N ATOM 390 CE2 TRP X 324 2.897 18.213 62.479 1.00 58.95 C ANISOU 390 CE2 TRP X 324 6060 8511 7828 -1038 71 100 C ATOM 391 CE3 TRP X 324 3.385 18.526 60.125 1.00 56.79 C ANISOU 391 CE3 TRP X 324 5803 8161 7612 -781 -356 -47 C ATOM 392 CZ2 TRP X 324 3.857 17.203 62.595 1.00 58.23 C ANISOU 392 CZ2 TRP X 324 6288 8199 7635 -1112 -1 190 C ATOM 393 CZ3 TRP X 324 4.340 17.521 60.240 1.00 55.98 C ANISOU 393 CZ3 TRP X 324 5995 7854 7418 -854 -396 17 C ATOM 394 CH2 TRP X 324 4.566 16.871 61.468 1.00 56.80 C ANISOU 394 CH2 TRP X 324 6242 7880 7459 -1008 -234 137 C ATOM 395 N ASP X 325 0.449 24.070 59.750 1.00 59.85 N ANISOU 395 N ASP X 325 5151 9222 8365 69 -264 -342 N ATOM 396 CA ASP X 325 -0.171 25.012 58.820 1.00 61.02 C ANISOU 396 CA ASP X 325 5120 9432 8633 304 -464 -406 C ATOM 397 C ASP X 325 0.834 25.991 58.215 1.00 58.74 C ANISOU 397 C ASP X 325 5120 9011 8188 542 -576 -368 C ATOM 398 O ASP X 325 0.556 26.615 57.187 1.00 59.52 O ANISOU 398 O ASP X 325 5186 9104 8322 724 -802 -381 O ATOM 399 CB ASP X 325 -1.299 25.785 59.509 1.00 63.76 C ANISOU 399 CB ASP X 325 5104 9946 9172 411 -302 -491 C ATOM 400 CG ASP X 325 -2.470 24.898 59.899 1.00 67.15 C ANISOU 400 CG ASP X 325 5169 10537 9806 172 -202 -538 C ATOM 401 OD1 ASP X 325 -2.476 23.702 59.531 1.00 67.52 O ANISOU 401 OD1 ASP X 325 5249 10544 9860 -79 -304 -504 O ATOM 402 OD2 ASP X 325 -3.390 25.404 60.577 1.00 70.11 O ANISOU 402 OD2 ASP X 325 5217 11074 10348 231 -8 -618 O ATOM 403 N GLN X 326 1.994 26.124 58.856 1.00 56.29 N ANISOU 403 N GLN X 326 5089 8593 7703 531 -426 -315 N ATOM 404 CA GLN X 326 3.048 27.016 58.376 1.00 54.28 C ANISOU 404 CA GLN X 326 5104 8207 7313 706 -493 -274 C ATOM 405 C GLN X 326 4.254 26.254 57.831 1.00 52.14 C ANISOU 405 C GLN X 326 5117 7814 6880 607 -568 -211 C ATOM 406 O GLN X 326 4.620 25.194 58.344 1.00 51.44 O ANISOU 406 O GLN X 326 5094 7703 6749 424 -494 -190 O ATOM 407 CB GLN X 326 3.498 27.975 59.481 1.00 53.70 C ANISOU 407 CB GLN X 326 5109 8102 7191 798 -283 -290 C ATOM 408 CG GLN X 326 2.540 29.121 59.767 1.00 55.68 C ANISOU 408 CG GLN X 326 5148 8419 7587 999 -229 -371 C ATOM 409 CD GLN X 326 3.122 30.149 60.725 1.00 55.11 C ANISOU 409 CD GLN X 326 5223 8271 7442 1103 -51 -408 C ATOM 410 OE1 GLN X 326 4.301 30.496 60.647 1.00 53.00 O ANISOU 410 OE1 GLN X 326 5229 7864 7042 1110 -72 -360 O ATOM 411 NE2 GLN X 326 2.289 30.648 61.629 1.00 57.49 N ANISOU 411 NE2 GLN X 326 5334 8669 7838 1179 130 -511 N ATOM 412 N ASN X 327 4.860 26.814 56.787 1.00 51.45 N ANISOU 412 N ASN X 327 5202 7642 6704 738 -706 -179 N ATOM 413 CA ASN X 327 6.074 26.270 56.175 1.00 49.75 C ANISOU 413 CA ASN X 327 5246 7320 6336 684 -747 -137 C ATOM 414 C ASN X 327 7.152 27.363 56.037 1.00 48.55 C ANISOU 414 C ASN X 327 5292 7068 6086 809 -691 -89 C ATOM 415 O ASN X 327 6.919 28.498 56.455 1.00 48.90 O ANISOU 415 O ASN X 327 5295 7101 6181 928 -636 -91 O ATOM 416 CB ASN X 327 5.742 25.599 54.831 1.00 50.67 C ANISOU 416 CB ASN X 327 5392 7444 6416 663 -965 -155 C ATOM 417 CG ASN X 327 5.176 26.567 53.807 1.00 51.83 C ANISOU 417 CG ASN X 327 5527 7612 6552 845 -1143 -142 C ATOM 418 OD1 ASN X 327 5.859 27.481 53.349 1.00 51.03 O ANISOU 418 OD1 ASN X 327 5612 7432 6344 971 -1137 -82 O ATOM 419 ND2 ASN X 327 3.925 26.353 53.429 1.00 53.83 N ANISOU 419 ND2 ASN X 327 5563 7967 6922 850 -1316 -193 N ATOM 420 N PRO X 328 8.335 27.030 55.467 1.00 47.45 N ANISOU 420 N PRO X 328 5359 6846 5823 776 -692 -57 N ATOM 421 CA PRO X 328 9.411 28.031 55.367 1.00 46.68 C ANISOU 421 CA PRO X 328 5423 6656 5656 850 -614 -10 C ATOM 422 C PRO X 328 9.067 29.287 54.561 1.00 47.87 C ANISOU 422 C PRO X 328 5634 6763 5789 1004 -693 36 C ATOM 423 O PRO X 328 9.735 30.311 54.718 1.00 47.60 O ANISOU 423 O PRO X 328 5709 6635 5742 1053 -611 76 O ATOM 424 CB PRO X 328 10.544 27.259 54.682 1.00 45.87 C ANISOU 424 CB PRO X 328 5477 6508 5444 786 -606 0 C ATOM 425 CG PRO X 328 10.295 25.846 55.042 1.00 45.71 C ANISOU 425 CG PRO X 328 5390 6521 5457 670 -631 -48 C ATOM 426 CD PRO X 328 8.806 25.696 55.045 1.00 47.07 C ANISOU 426 CD PRO X 328 5391 6777 5715 660 -732 -76 C ATOM 427 N LYS X 329 8.042 29.211 53.715 1.00 49.51 N ANISOU 427 N LYS X 329 5783 7025 6001 1074 -868 36 N ATOM 428 CA LYS X 329 7.614 30.368 52.928 1.00 51.27 C ANISOU 428 CA LYS X 329 6081 7195 6203 1246 -987 100 C ATOM 429 C LYS X 329 6.605 31.253 53.666 1.00 52.58 C ANISOU 429 C LYS X 329 6058 7374 6546 1382 -994 67 C ATOM 430 O LYS X 329 6.224 32.313 53.164 1.00 54.28 O ANISOU 430 O LYS X 329 6333 7513 6777 1557 -1097 121 O ATOM 431 CB LYS X 329 7.064 29.940 51.565 1.00 52.86 C ANISOU 431 CB LYS X 329 6343 7444 6297 1284 -1216 118 C ATOM 432 CG LYS X 329 8.119 29.380 50.627 1.00 52.46 C ANISOU 432 CG LYS X 329 6545 7356 6030 1202 -1191 148 C ATOM 433 CD LYS X 329 7.559 29.123 49.238 1.00 54.93 C ANISOU 433 CD LYS X 329 6975 7709 6185 1258 -1432 161 C ATOM 434 CE LYS X 329 7.637 30.360 48.358 1.00 56.82 C ANISOU 434 CE LYS X 329 7444 7860 6284 1408 -1510 295 C ATOM 435 NZ LYS X 329 7.279 30.038 46.949 1.00 59.39 N ANISOU 435 NZ LYS X 329 7956 8228 6382 1450 -1744 314 N ATOM 436 N SER X 330 6.181 30.818 54.854 1.00 52.23 N ANISOU 436 N SER X 330 5801 7416 6626 1310 -874 -18 N ATOM 437 CA SER X 330 5.315 31.625 55.718 1.00 53.57 C ANISOU 437 CA SER X 330 5783 7611 6959 1437 -812 -80 C ATOM 438 C SER X 330 6.073 32.843 56.238 1.00 53.19 C ANISOU 438 C SER X 330 5908 7405 6894 1518 -688 -65 C ATOM 439 O SER X 330 7.304 32.844 56.286 1.00 51.48 O ANISOU 439 O SER X 330 5893 7099 6566 1415 -605 -22 O ATOM 440 CB SER X 330 4.777 30.797 56.889 1.00 53.44 C ANISOU 440 CB SER X 330 5536 7735 7034 1305 -665 -170 C ATOM 441 OG SER X 330 4.033 29.682 56.432 1.00 54.17 O ANISOU 441 OG SER X 330 5459 7949 7171 1199 -780 -189 O ATOM 442 N THR X 331 5.332 33.877 56.627 1.00 55.10 N ANISOU 442 N THR X 331 6058 7609 7268 1705 -680 -115 N ATOM 443 CA THR X 331 5.937 35.140 57.048 1.00 55.37 C ANISOU 443 CA THR X 331 6275 7454 7307 1796 -592 -116 C ATOM 444 C THR X 331 5.723 35.437 58.534 1.00 55.71 C ANISOU 444 C THR X 331 6212 7528 7427 1803 -391 -257 C ATOM 445 O THR X 331 4.934 34.766 59.207 1.00 56.27 O ANISOU 445 O THR X 331 6044 7776 7558 1765 -307 -343 O ATOM 446 CB THR X 331 5.415 36.332 56.204 1.00 57.73 C ANISOU 446 CB THR X 331 6654 7602 7675 2045 -758 -54 C ATOM 447 OG1 THR X 331 3.996 36.449 56.359 1.00 60.16 O ANISOU 447 OG1 THR X 331 6675 8019 8164 2232 -833 -139 O ATOM 448 CG2 THR X 331 5.750 36.146 54.726 1.00 57.71 C ANISOU 448 CG2 THR X 331 6839 7556 7532 2031 -946 100 C ATOM 449 N PHE X 332 6.449 36.436 59.034 1.00 55.73 N ANISOU 449 N PHE X 332 6409 7352 7414 1833 -306 -284 N ATOM 450 CA PHE X 332 6.263 36.947 60.392 1.00 56.58 C ANISOU 450 CA PHE X 332 6478 7453 7565 1873 -131 -439 C ATOM 451 C PHE X 332 6.621 38.431 60.475 1.00 57.92 C ANISOU 451 C PHE X 332 6858 7359 7788 2014 -133 -471 C ATOM 452 O PHE X 332 7.400 38.940 59.666 1.00 57.56 O ANISOU 452 O PHE X 332 7030 7131 7708 1990 -228 -352 O ATOM 453 CB PHE X 332 7.077 36.130 61.405 1.00 54.70 C ANISOU 453 CB PHE X 332 6284 7308 7190 1639 9 -479 C ATOM 454 CG PHE X 332 8.564 36.344 61.315 1.00 53.21 C ANISOU 454 CG PHE X 332 6340 6974 6902 1500 -10 -420 C ATOM 455 CD1 PHE X 332 9.192 37.303 62.107 1.00 53.93 C ANISOU 455 CD1 PHE X 332 6592 6913 6983 1499 58 -511 C ATOM 456 CD2 PHE X 332 9.339 35.579 60.450 1.00 51.58 C ANISOU 456 CD2 PHE X 332 6189 6787 6623 1366 -92 -293 C ATOM 457 CE1 PHE X 332 10.567 37.505 62.031 1.00 52.89 C ANISOU 457 CE1 PHE X 332 6640 6658 6794 1349 32 -467 C ATOM 458 CE2 PHE X 332 10.718 35.769 60.370 1.00 50.72 C ANISOU 458 CE2 PHE X 332 6252 6566 6454 1237 -88 -250 C ATOM 459 CZ PHE X 332 11.332 36.735 61.162 1.00 51.33 C ANISOU 459 CZ PHE X 332 6455 6500 6545 1219 -31 -333 C ATOM 460 N LYS X 333 6.045 39.115 61.457 1.00 59.79 N ANISOU 460 N LYS X 333 7039 7569 8106 2153 -12 -637 N ATOM 461 CA LYS X 333 6.305 40.532 61.665 1.00 61.60 C ANISOU 461 CA LYS X 333 7479 7520 8404 2295 -8 -704 C ATOM 462 C LYS X 333 7.558 40.705 62.522 1.00 60.44 C ANISOU 462 C LYS X 333 7550 7280 8132 2088 88 -767 C ATOM 463 O LYS X 333 7.612 40.227 63.658 1.00 60.05 O ANISOU 463 O LYS X 333 7448 7377 7989 1989 230 -894 O ATOM 464 CB LYS X 333 5.094 41.185 62.335 1.00 64.63 C ANISOU 464 CB LYS X 333 7702 7914 8939 2563 82 -888 C ATOM 465 CG LYS X 333 5.056 42.701 62.270 1.00 67.31 C ANISOU 465 CG LYS X 333 8241 7925 9407 2795 34 -950 C ATOM 466 CD LYS X 333 3.897 43.234 63.105 1.00 70.74 C ANISOU 466 CD LYS X 333 8491 8397 9989 3067 169 -1179 C ATOM 467 CE LYS X 333 3.746 44.739 62.970 1.00 73.84 C ANISOU 467 CE LYS X 333 9083 8429 10543 3346 99 -1247 C ATOM 468 NZ LYS X 333 2.651 45.260 63.833 1.00 77.37 N ANISOU 468 NZ LYS X 333 9343 8912 11140 3637 258 -1506 N ATOM 469 N LYS X 334 8.564 41.379 61.968 1.00 60.26 N ANISOU 469 N LYS X 334 7773 7017 8104 2012 7 -673 N ATOM 470 CA LYS X 334 9.808 41.650 62.692 1.00 59.65 C ANISOU 470 CA LYS X 334 7883 6834 7948 1807 60 -738 C ATOM 471 C LYS X 334 9.619 42.732 63.750 1.00 62.08 C ANISOU 471 C LYS X 334 8310 6970 8305 1918 140 -955 C ATOM 472 O LYS X 334 8.599 43.428 63.765 1.00 64.36 O ANISOU 472 O LYS X 334 8565 7173 8716 2179 155 -1038 O ATOM 473 CB LYS X 334 10.935 42.056 61.734 1.00 59.14 C ANISOU 473 CB LYS X 334 8011 6569 7890 1665 -27 -573 C ATOM 474 CG LYS X 334 11.690 40.891 61.105 1.00 56.75 C ANISOU 474 CG LYS X 334 7635 6443 7482 1462 -50 -426 C ATOM 475 CD LYS X 334 13.175 41.215 60.896 1.00 56.77 C ANISOU 475 CD LYS X 334 7793 6302 7475 1234 -49 -366 C ATOM 476 CE LYS X 334 13.423 42.186 59.739 1.00 58.49 C ANISOU 476 CE LYS X 334 8207 6259 7757 1254 -92 -210 C ATOM 477 NZ LYS X 334 13.262 41.552 58.399 1.00 57.73 N ANISOU 477 NZ LYS X 334 8085 6263 7587 1273 -139 -15 N ATOM 478 N ALA X 335 10.615 42.864 64.627 1.00 61.86 N ANISOU 478 N ALA X 335 8423 6893 8188 1729 176 -1060 N ATOM 479 CA ALA X 335 10.635 43.901 65.660 1.00 64.35 C ANISOU 479 CA ALA X 335 8909 7023 8518 1793 235 -1291 C ATOM 480 C ALA X 335 10.551 45.310 65.064 1.00 66.86 C ANISOU 480 C ALA X 335 9423 6962 9016 1943 166 -1285 C ATOM 481 O ALA X 335 9.953 46.209 65.664 1.00 69.65 O ANISOU 481 O ALA X 335 9867 7154 9443 2142 220 -1479 O ATOM 482 CB ALA X 335 11.880 43.759 66.527 1.00 63.72 C ANISOU 482 CB ALA X 335 8957 6947 8306 1527 220 -1378 C ATOM 483 N ASP X 336 11.144 45.486 63.881 1.00 66.18 N ANISOU 483 N ASP X 336 9421 6728 8993 1852 58 -1061 N ATOM 484 CA ASP X 336 11.095 46.757 63.150 1.00 68.66 C ANISOU 484 CA ASP X 336 9959 6661 9465 1973 -20 -989 C ATOM 485 C ASP X 336 9.814 46.928 62.329 1.00 69.84 C ANISOU 485 C ASP X 336 10020 6796 9719 2299 -83 -893 C ATOM 486 O ASP X 336 9.607 47.971 61.710 1.00 72.35 O ANISOU 486 O ASP X 336 10532 6789 10167 2455 -171 -819 O ATOM 487 CB ASP X 336 12.336 46.937 62.260 1.00 68.05 C ANISOU 487 CB ASP X 336 10042 6421 9391 1708 -82 -781 C ATOM 488 CG ASP X 336 12.594 45.744 61.356 1.00 65.52 C ANISOU 488 CG ASP X 336 9553 6375 8963 1588 -98 -567 C ATOM 489 OD1 ASP X 336 12.366 45.863 60.133 1.00 65.95 O ANISOU 489 OD1 ASP X 336 9668 6354 9033 1660 -164 -354 O ATOM 490 OD2 ASP X 336 13.028 44.687 61.869 1.00 63.39 O ANISOU 490 OD2 ASP X 336 9115 6385 8582 1429 -53 -613 O ATOM 491 N GLY X 337 8.965 45.903 62.322 1.00 68.37 N ANISOU 491 N GLY X 337 9542 6951 9484 2394 -56 -890 N ATOM 492 CA GLY X 337 7.635 46.000 61.718 1.00 69.86 C ANISOU 492 CA GLY X 337 9573 7176 9794 2714 -131 -848 C ATOM 493 C GLY X 337 7.518 45.549 60.274 1.00 68.86 C ANISOU 493 C GLY X 337 9415 7104 9645 2720 -293 -577 C ATOM 494 O GLY X 337 6.435 45.609 59.691 1.00 70.38 O ANISOU 494 O GLY X 337 9471 7332 9936 2983 -407 -531 O ATOM 495 N SER X 338 8.628 45.101 59.693 1.00 66.61 N ANISOU 495 N SER X 338 9248 6831 9227 2438 -309 -410 N ATOM 496 CA SER X 338 8.619 44.595 58.323 1.00 65.80 C ANISOU 496 CA SER X 338 9152 6799 9049 2415 -440 -167 C ATOM 497 C SER X 338 8.318 43.095 58.288 1.00 63.17 C ANISOU 497 C SER X 338 8530 6855 8614 2325 -424 -167 C ATOM 498 O SER X 338 8.776 42.341 59.149 1.00 61.11 O ANISOU 498 O SER X 338 8158 6775 8283 2141 -296 -274 O ATOM 499 CB SER X 338 9.937 44.915 57.607 1.00 65.38 C ANISOU 499 CB SER X 338 9378 6554 8908 2170 -434 12 C ATOM 500 OG SER X 338 11.057 44.449 58.339 1.00 63.41 O ANISOU 500 OG SER X 338 9103 6395 8593 1879 -299 -71 O ATOM 501 N GLU X 339 7.535 42.678 57.294 1.00 63.54 N ANISOU 501 N GLU X 339 8476 7013 8653 2457 -575 -48 N ATOM 502 CA GLU X 339 7.134 41.279 57.145 1.00 61.55 C ANISOU 502 CA GLU X 339 7963 7096 8327 2377 -590 -50 C ATOM 503 C GLU X 339 8.072 40.523 56.204 1.00 59.51 C ANISOU 503 C GLU X 339 7825 6897 7887 2153 -619 114 C ATOM 504 O GLU X 339 8.278 40.931 55.061 1.00 60.56 O ANISOU 504 O GLU X 339 8165 6895 7949 2185 -733 287 O ATOM 505 CB GLU X 339 5.687 41.186 56.649 1.00 63.54 C ANISOU 505 CB GLU X 339 7994 7456 8689 2638 -756 -52 C ATOM 506 N VAL X 340 8.643 39.428 56.697 1.00 56.94 N ANISOU 506 N VAL X 340 7387 6768 7478 1935 -507 60 N ATOM 507 CA VAL X 340 9.546 38.588 55.903 1.00 55.20 C ANISOU 507 CA VAL X 340 7246 6625 7102 1738 -507 176 C ATOM 508 C VAL X 340 9.242 37.099 56.070 1.00 53.48 C ANISOU 508 C VAL X 340 6804 6678 6835 1645 -505 121 C ATOM 509 O VAL X 340 8.861 36.653 57.154 1.00 52.92 O ANISOU 509 O VAL X 340 6552 6729 6823 1623 -423 -5 O ATOM 510 CB VAL X 340 11.046 38.836 56.242 1.00 54.13 C ANISOU 510 CB VAL X 340 7267 6377 6923 1522 -367 186 C ATOM 511 CG1 VAL X 340 11.520 40.164 55.676 1.00 56.05 C ANISOU 511 CG1 VAL X 340 7778 6330 7187 1545 -376 296 C ATOM 512 CG2 VAL X 340 11.303 38.757 57.751 1.00 53.22 C ANISOU 512 CG2 VAL X 340 7047 6305 6868 1446 -252 13 C ATOM 513 N SER X 341 9.413 36.337 54.991 1.00 52.99 N ANISOU 513 N SER X 341 6784 6696 6654 1585 -587 218 N ATOM 514 CA SER X 341 9.293 34.885 55.055 1.00 51.52 C ANISOU 514 CA SER X 341 6436 6718 6419 1470 -589 170 C ATOM 515 C SER X 341 10.513 34.293 55.749 1.00 49.61 C ANISOU 515 C SER X 341 6215 6499 6133 1274 -437 133 C ATOM 516 O SER X 341 11.601 34.874 55.704 1.00 49.40 O ANISOU 516 O SER X 341 6340 6349 6080 1202 -357 173 O ATOM 517 CB SER X 341 9.140 34.286 53.656 1.00 51.96 C ANISOU 517 CB SER X 341 6566 6830 6346 1474 -733 260 C ATOM 518 OG SER X 341 10.369 34.311 52.952 1.00 51.34 O ANISOU 518 OG SER X 341 6707 6675 6123 1366 -660 347 O ATOM 519 N PHE X 342 10.327 33.140 56.389 1.00 48.61 N ANISOU 519 N PHE X 342 5933 6522 6013 1185 -408 61 N ATOM 520 CA PHE X 342 11.421 32.441 57.066 1.00 47.15 C ANISOU 520 CA PHE X 342 5760 6363 5790 1026 -307 31 C ATOM 521 C PHE X 342 12.559 32.161 56.096 1.00 46.72 C ANISOU 521 C PHE X 342 5836 6268 5647 950 -296 101 C ATOM 522 O PHE X 342 13.730 32.219 56.468 1.00 46.21 O ANISOU 522 O PHE X 342 5812 6161 5585 856 -212 93 O ATOM 523 CB PHE X 342 10.936 31.132 57.700 1.00 46.49 C ANISOU 523 CB PHE X 342 5529 6423 5710 949 -305 -21 C ATOM 524 CG PHE X 342 9.802 31.306 58.677 1.00 47.50 C ANISOU 524 CG PHE X 342 5507 6623 5915 998 -264 -93 C ATOM 525 CD1 PHE X 342 9.989 32.002 59.871 1.00 47.72 C ANISOU 525 CD1 PHE X 342 5555 6617 5958 1006 -155 -161 C ATOM 526 CD2 PHE X 342 8.550 30.759 58.409 1.00 48.49 C ANISOU 526 CD2 PHE X 342 5463 6861 6100 1027 -326 -109 C ATOM 527 CE1 PHE X 342 8.942 32.160 60.773 1.00 48.84 C ANISOU 527 CE1 PHE X 342 5563 6841 6152 1057 -75 -244 C ATOM 528 CE2 PHE X 342 7.495 30.911 59.307 1.00 49.59 C ANISOU 528 CE2 PHE X 342 5425 7089 6327 1066 -248 -184 C ATOM 529 CZ PHE X 342 7.692 31.614 60.489 1.00 49.97 C ANISOU 529 CZ PHE X 342 5508 7109 6369 1088 -104 -252 C ATOM 530 N LEU X 343 12.199 31.872 54.849 1.00 47.42 N ANISOU 530 N LEU X 343 5981 6379 5656 995 -384 159 N ATOM 531 CA LEU X 343 13.163 31.667 53.777 1.00 47.65 C ANISOU 531 CA LEU X 343 6155 6380 5567 942 -346 220 C ATOM 532 C LEU X 343 14.027 32.915 53.571 1.00 48.51 C ANISOU 532 C LEU X 343 6409 6346 5675 921 -247 294 C ATOM 533 O LEU X 343 15.249 32.814 53.445 1.00 48.24 O ANISOU 533 O LEU X 343 6410 6293 5623 813 -125 302 O ATOM 534 CB LEU X 343 12.428 31.303 52.486 1.00 48.78 C ANISOU 534 CB LEU X 343 6374 6570 5589 1012 -480 262 C ATOM 535 CG LEU X 343 13.129 30.402 51.469 1.00 49.06 C ANISOU 535 CG LEU X 343 6518 6649 5471 951 -451 262 C ATOM 536 CD1 LEU X 343 13.250 28.974 51.989 1.00 47.83 C ANISOU 536 CD1 LEU X 343 6234 6576 5363 876 -448 157 C ATOM 537 CD2 LEU X 343 12.370 30.422 50.150 1.00 51.01 C ANISOU 537 CD2 LEU X 343 6906 6918 5557 1035 -608 313 C ATOM 538 N GLU X 344 13.382 34.083 53.557 1.00 49.91 N ANISOU 538 N GLU X 344 6657 6414 5893 1024 -300 342 N ATOM 539 CA GLU X 344 14.066 35.372 53.414 1.00 51.21 C ANISOU 539 CA GLU X 344 6985 6393 6078 996 -219 420 C ATOM 540 C GLU X 344 14.890 35.725 54.648 1.00 50.45 C ANISOU 540 C GLU X 344 6817 6242 6109 886 -113 333 C ATOM 541 O GLU X 344 16.026 36.184 54.529 1.00 50.98 O ANISOU 541 O GLU X 344 6955 6219 6193 756 -3 368 O ATOM 542 CB GLU X 344 13.059 36.492 53.149 1.00 53.10 C ANISOU 542 CB GLU X 344 7329 6496 6348 1167 -333 485 C ATOM 543 CG GLU X 344 12.445 36.490 51.758 1.00 55.15 C ANISOU 543 CG GLU X 344 7737 6759 6457 1274 -469 610 C ATOM 544 CD GLU X 344 11.265 37.445 51.636 1.00 57.78 C ANISOU 544 CD GLU X 344 8115 6978 6858 1493 -639 655 C ATOM 545 OE1 GLU X 344 10.421 37.235 50.734 1.00 59.30 O ANISOU 545 OE1 GLU X 344 8344 7229 6959 1621 -824 716 O ATOM 546 OE2 GLU X 344 11.177 38.402 52.439 1.00 58.18 O ANISOU 546 OE2 GLU X 344 8166 6879 7060 1550 -603 618 O ATOM 547 N TYR X 345 14.305 35.510 55.825 1.00 49.62 N ANISOU 547 N TYR X 345 6568 6197 6085 929 -146 217 N ATOM 548 CA TYR X 345 14.938 35.845 57.101 1.00 49.22 C ANISOU 548 CA TYR X 345 6474 6105 6122 842 -84 116 C ATOM 549 C TYR X 345 16.292 35.164 57.293 1.00 48.41 C ANISOU 549 C TYR X 345 6312 6063 6016 676 -19 96 C ATOM 550 O TYR X 345 17.289 35.830 57.568 1.00 49.11 O ANISOU 550 O TYR X 345 6436 6052 6171 564 35 81 O ATOM 551 CB TYR X 345 13.997 35.512 58.267 1.00 48.68 C ANISOU 551 CB TYR X 345 6278 6133 6083 916 -113 0 C ATOM 552 CG TYR X 345 14.568 35.793 59.643 1.00 48.30 C ANISOU 552 CG TYR X 345 6220 6060 6070 835 -68 -116 C ATOM 553 CD1 TYR X 345 14.770 37.101 60.084 1.00 49.45 C ANISOU 553 CD1 TYR X 345 6480 6024 6284 845 -47 -170 C ATOM 554 CD2 TYR X 345 14.890 34.749 60.511 1.00 46.95 C ANISOU 554 CD2 TYR X 345 5954 6030 5853 752 -65 -174 C ATOM 555 CE1 TYR X 345 15.291 37.364 61.350 1.00 49.58 C ANISOU 555 CE1 TYR X 345 6509 6019 6308 765 -32 -300 C ATOM 556 CE2 TYR X 345 15.410 34.999 61.780 1.00 47.07 C ANISOU 556 CE2 TYR X 345 5990 6031 5862 683 -57 -279 C ATOM 557 CZ TYR X 345 15.608 36.309 62.192 1.00 48.46 C ANISOU 557 CZ TYR X 345 6275 6045 6093 687 -43 -352 C ATOM 558 OH TYR X 345 16.122 36.567 63.444 1.00 48.67 O ANISOU 558 OH TYR X 345 6342 6057 6091 613 -58 -478 O ATOM 559 N TYR X 346 16.324 33.845 57.130 1.00 47.34 N ANISOU 559 N TYR X 346 6078 6082 5824 663 -37 88 N ATOM 560 CA TYR X 346 17.532 33.064 57.394 1.00 46.86 C ANISOU 560 CA TYR X 346 5933 6086 5785 551 0 53 C ATOM 561 C TYR X 346 18.591 33.158 56.301 1.00 47.85 C ANISOU 561 C TYR X 346 6094 6184 5902 477 101 117 C ATOM 562 O TYR X 346 19.746 32.801 56.522 1.00 48.04 O ANISOU 562 O TYR X 346 6018 6241 5991 386 149 78 O ATOM 563 CB TYR X 346 17.173 31.608 57.686 1.00 45.63 C ANISOU 563 CB TYR X 346 5683 6066 5587 577 -56 19 C ATOM 564 CG TYR X 346 16.389 31.465 58.964 1.00 45.14 C ANISOU 564 CG TYR X 346 5576 6045 5529 600 -107 -42 C ATOM 565 CD1 TYR X 346 16.998 31.672 60.198 1.00 45.10 C ANISOU 565 CD1 TYR X 346 5553 6029 5551 539 -117 -109 C ATOM 566 CD2 TYR X 346 15.036 31.140 58.941 1.00 44.85 C ANISOU 566 CD2 TYR X 346 5511 6068 5462 675 -141 -40 C ATOM 567 CE1 TYR X 346 16.281 31.558 61.373 1.00 45.29 C ANISOU 567 CE1 TYR X 346 5573 6100 5534 555 -134 -165 C ATOM 568 CE2 TYR X 346 14.309 31.022 60.115 1.00 44.97 C ANISOU 568 CE2 TYR X 346 5477 6135 5472 681 -138 -97 C ATOM 569 CZ TYR X 346 14.940 31.229 61.328 1.00 45.20 C ANISOU 569 CZ TYR X 346 5529 6152 5490 623 -122 -156 C ATOM 570 OH TYR X 346 14.234 31.110 62.500 1.00 45.79 O ANISOU 570 OH TYR X 346 5591 6289 5515 623 -92 -212 O ATOM 571 N ARG X 347 18.196 33.640 55.127 1.00 48.99 N ANISOU 571 N ARG X 347 6378 6274 5963 519 132 215 N ATOM 572 CA ARG X 347 19.136 33.892 54.046 1.00 50.52 C ANISOU 572 CA ARG X 347 6646 6434 6112 435 271 292 C ATOM 573 C ARG X 347 19.810 35.247 54.268 1.00 52.01 C ANISOU 573 C ARG X 347 6897 6459 6403 318 352 330 C ATOM 574 O ARG X 347 21.018 35.386 54.081 1.00 53.02 O ANISOU 574 O ARG X 347 6965 6581 6598 173 487 333 O ATOM 575 CB ARG X 347 18.411 33.853 52.698 1.00 51.44 C ANISOU 575 CB ARG X 347 6938 6555 6050 522 256 395 C ATOM 576 CG ARG X 347 19.319 33.875 51.473 1.00 53.66 C ANISOU 576 CG ARG X 347 7328 6842 6218 439 431 473 C ATOM 577 CD ARG X 347 18.506 33.958 50.181 1.00 56.11 C ANISOU 577 CD ARG X 347 7870 7145 6302 534 379 582 C ATOM 578 NE ARG X 347 17.550 35.070 50.193 1.00 57.98 N ANISOU 578 NE ARG X 347 8253 7236 6537 621 250 680 N ATOM 579 CZ ARG X 347 17.822 36.317 49.806 1.00 60.54 C ANISOU 579 CZ ARG X 347 8771 7382 6848 569 322 816 C ATOM 580 NH1 ARG X 347 19.032 36.643 49.361 1.00 62.20 N ANISOU 580 NH1 ARG X 347 9041 7552 7040 395 548 877 N ATOM 581 NH2 ARG X 347 16.876 37.246 49.864 1.00 61.38 N ANISOU 581 NH2 ARG X 347 9007 7340 6973 691 175 891 N ATOM 582 N LYS X 348 19.016 36.233 54.681 1.00 52.53 N ANISOU 582 N LYS X 348 7069 6387 6501 380 272 346 N ATOM 583 CA LYS X 348 19.501 37.592 54.916 1.00 54.32 C ANISOU 583 CA LYS X 348 7398 6406 6833 275 325 375 C ATOM 584 C LYS X 348 20.310 37.706 56.206 1.00 54.07 C ANISOU 584 C LYS X 348 7216 6370 6957 152 312 234 C ATOM 585 O LYS X 348 21.425 38.231 56.201 1.00 55.50 O ANISOU 585 O LYS X 348 7368 6474 7244 -29 403 235 O ATOM 586 CB LYS X 348 18.330 38.583 54.951 1.00 55.23 C ANISOU 586 CB LYS X 348 7688 6353 6944 423 226 418 C ATOM 587 CG LYS X 348 17.751 38.950 53.586 1.00 56.97 C ANISOU 587 CG LYS X 348 8124 6495 7026 515 217 593 C ATOM 588 CD LYS X 348 18.518 40.095 52.920 1.00 60.31 C ANISOU 588 CD LYS X 348 8762 6690 7460 370 339 736 C ATOM 589 CE LYS X 348 18.116 41.458 53.482 1.00 62.05 C ANISOU 589 CE LYS X 348 9134 6629 7811 415 271 735 C ATOM 590 NZ LYS X 348 18.918 42.560 52.879 1.00 64.95 N ANISOU 590 NZ LYS X 348 9728 6740 8207 234 397 883 N ATOM 591 N GLN X 349 19.745 37.204 57.302 1.00 52.64 N ANISOU 591 N GLN X 349 6940 6279 6782 241 197 115 N ATOM 592 CA GLN X 349 20.315 37.392 58.635 1.00 52.81 C ANISOU 592 CA GLN X 349 6873 6288 6901 153 140 -24 C ATOM 593 C GLN X 349 21.484 36.451 58.948 1.00 52.44 C ANISOU 593 C GLN X 349 6625 6392 6906 45 136 -79 C ATOM 594 O GLN X 349 22.472 36.869 59.556 1.00 53.58 O ANISOU 594 O GLN X 349 6694 6493 7170 -98 115 -155 O ATOM 595 CB GLN X 349 19.220 37.267 59.703 1.00 51.92 C ANISOU 595 CB GLN X 349 6774 6215 6736 291 41 -124 C ATOM 596 CG GLN X 349 19.638 37.686 61.111 1.00 52.69 C ANISOU 596 CG GLN X 349 6862 6273 6883 216 -26 -277 C ATOM 597 CD GLN X 349 19.952 39.165 61.225 1.00 54.86 C ANISOU 597 CD GLN X 349 7278 6302 7262 133 -11 -316 C ATOM 598 OE1 GLN X 349 21.109 39.551 61.396 1.00 56.17 O ANISOU 598 OE1 GLN X 349 7405 6401 7534 -52 -17 -354 O ATOM 599 NE2 GLN X 349 18.924 40.003 61.124 1.00 55.64 N ANISOU 599 NE2 GLN X 349 7533 6253 7355 270 -2 -313 N ATOM 600 N TYR X 350 21.368 35.191 58.533 1.00 51.16 N ANISOU 600 N TYR X 350 6374 6393 6669 121 139 -51 N ATOM 601 CA TYR X 350 22.348 34.165 58.894 1.00 50.94 C ANISOU 601 CA TYR X 350 6157 6499 6697 77 107 -109 C ATOM 602 C TYR X 350 22.986 33.464 57.693 1.00 51.26 C ANISOU 602 C TYR X 350 6119 6619 6737 71 233 -52 C ATOM 603 O TYR X 350 23.885 32.632 57.865 1.00 51.54 O ANISOU 603 O TYR X 350 5978 6753 6850 57 221 -106 O ATOM 604 CB TYR X 350 21.705 33.115 59.804 1.00 49.53 C ANISOU 604 CB TYR X 350 5951 6429 6438 184 -23 -160 C ATOM 605 CG TYR X 350 21.162 33.647 61.113 1.00 49.78 C ANISOU 605 CG TYR X 350 6054 6420 6438 190 -121 -240 C ATOM 606 CD1 TYR X 350 19.803 33.923 61.264 1.00 49.44 C ANISOU 606 CD1 TYR X 350 6125 6354 6302 293 -113 -232 C ATOM 607 CD2 TYR X 350 22.004 33.860 62.203 1.00 50.86 C ANISOU 607 CD2 TYR X 350 6137 6554 6632 101 -223 -337 C ATOM 608 CE1 TYR X 350 19.296 34.403 62.466 1.00 50.02 C ANISOU 608 CE1 TYR X 350 6268 6404 6333 310 -163 -326 C ATOM 609 CE2 TYR X 350 21.509 34.340 63.411 1.00 51.58 C ANISOU 609 CE2 TYR X 350 6331 6614 6650 109 -304 -428 C ATOM 610 CZ TYR X 350 20.155 34.610 63.535 1.00 51.21 C ANISOU 610 CZ TYR X 350 6408 6547 6502 216 -252 -425 C ATOM 611 OH TYR X 350 19.661 35.085 64.729 1.00 52.28 O ANISOU 611 OH TYR X 350 6648 6661 6552 234 -292 -535 O ATOM 612 N ASN X 351 22.527 33.803 56.488 1.00 51.60 N ANISOU 612 N ASN X 351 6303 6617 6685 95 347 50 N ATOM 613 CA ASN X 351 22.937 33.115 55.259 1.00 52.08 C ANISOU 613 CA ASN X 351 6348 6760 6679 109 484 96 C ATOM 614 C ASN X 351 22.791 31.594 55.386 1.00 50.81 C ANISOU 614 C ASN X 351 6092 6732 6478 226 406 31 C ATOM 615 O ASN X 351 23.753 30.833 55.231 1.00 51.37 O ANISOU 615 O ASN X 351 6010 6883 6622 221 465 -25 O ATOM 616 CB ASN X 351 24.356 33.526 54.834 1.00 54.18 C ANISOU 616 CB ASN X 351 6492 7023 7070 -50 663 97 C ATOM 617 CG ASN X 351 24.629 33.265 53.359 1.00 55.37 C ANISOU 617 CG ASN X 351 6714 7224 7098 -53 874 170 C ATOM 618 OD1 ASN X 351 23.727 33.329 52.520 1.00 54.91 O ANISOU 618 OD1 ASN X 351 6880 7139 6844 25 881 260 O ATOM 619 ND2 ASN X 351 25.885 32.977 53.038 1.00 56.89 N ANISOU 619 ND2 ASN X 351 6713 7499 7402 -141 1044 123 N ATOM 620 N GLN X 352 21.566 31.174 55.695 1.00 49.40 N ANISOU 620 N GLN X 352 5999 6564 6204 332 276 34 N ATOM 621 CA GLN X 352 21.218 29.767 55.834 1.00 48.36 C ANISOU 621 CA GLN X 352 5824 6518 6032 423 190 -11 C ATOM 622 C GLN X 352 20.080 29.430 54.879 1.00 48.03 C ANISOU 622 C GLN X 352 5923 6489 5836 503 171 33 C ATOM 623 O GLN X 352 18.950 29.901 55.049 1.00 47.57 O ANISOU 623 O GLN X 352 5940 6402 5730 540 93 69 O ATOM 624 CB GLN X 352 20.824 29.448 57.282 1.00 47.34 C ANISOU 624 CB GLN X 352 5644 6398 5944 437 39 -57 C ATOM 625 CG GLN X 352 21.986 29.465 58.276 1.00 47.96 C ANISOU 625 CG GLN X 352 5584 6485 6153 377 -7 -118 C ATOM 626 CD GLN X 352 22.973 28.325 58.066 1.00 48.48 C ANISOU 626 CD GLN X 352 5517 6609 6294 417 -9 -161 C ATOM 627 OE1 GLN X 352 22.609 27.246 57.599 1.00 48.18 O ANISOU 627 OE1 GLN X 352 5515 6593 6198 501 -20 -161 O ATOM 628 NE2 GLN X 352 24.230 28.561 58.420 1.00 49.68 N ANISOU 628 NE2 GLN X 352 5503 6775 6595 362 -10 -211 N ATOM 629 N GLU X 353 20.392 28.627 53.866 1.00 48.62 N ANISOU 629 N GLU X 353 6025 6611 5838 537 238 16 N ATOM 630 CA GLU X 353 19.420 28.262 52.841 1.00 48.87 C ANISOU 630 CA GLU X 353 6204 6660 5705 602 198 41 C ATOM 631 C GLU X 353 18.557 27.092 53.294 1.00 47.88 C ANISOU 631 C GLU X 353 6048 6562 5580 651 44 -13 C ATOM 632 O GLU X 353 19.062 25.997 53.551 1.00 47.83 O ANISOU 632 O GLU X 353 5976 6568 5627 666 33 -84 O ATOM 633 CB GLU X 353 20.121 27.933 51.518 1.00 50.38 C ANISOU 633 CB GLU X 353 6476 6885 5779 609 348 28 C ATOM 634 N ILE X 354 17.256 27.343 53.408 1.00 47.52 N ANISOU 634 N ILE X 354 6042 6516 5495 675 -71 19 N ATOM 635 CA ILE X 354 16.291 26.296 53.725 1.00 47.03 C ANISOU 635 CA ILE X 354 5947 6482 5439 686 -202 -22 C ATOM 636 C ILE X 354 15.865 25.619 52.422 1.00 48.09 C ANISOU 636 C ILE X 354 6194 6636 5440 719 -254 -52 C ATOM 637 O ILE X 354 15.163 26.212 51.598 1.00 48.98 O ANISOU 637 O ILE X 354 6398 6763 5448 755 -309 -9 O ATOM 638 CB ILE X 354 15.062 26.846 54.488 1.00 46.58 C ANISOU 638 CB ILE X 354 5830 6439 5427 689 -285 6 C ATOM 639 CG1 ILE X 354 15.494 27.500 55.806 1.00 45.79 C ANISOU 639 CG1 ILE X 354 5658 6317 5421 658 -232 10 C ATOM 640 CG2 ILE X 354 14.053 25.733 54.747 1.00 46.56 C ANISOU 640 CG2 ILE X 354 5771 6473 5444 662 -393 -31 C ATOM 641 CD1 ILE X 354 14.442 28.396 56.436 1.00 45.62 C ANISOU 641 CD1 ILE X 354 5600 6300 5433 689 -258 22 C ATOM 642 N THR X 355 16.307 24.378 52.245 1.00 48.33 N ANISOU 642 N THR X 355 6235 6654 5472 717 -254 -133 N ATOM 643 CA THR X 355 16.078 23.641 51.005 1.00 49.57 C ANISOU 643 CA THR X 355 6527 6817 5489 746 -296 -200 C ATOM 644 C THR X 355 14.685 23.015 50.943 1.00 49.87 C ANISOU 644 C THR X 355 6567 6861 5519 716 -489 -229 C ATOM 645 O THR X 355 14.044 23.029 49.893 1.00 51.13 O ANISOU 645 O THR X 355 6837 7049 5539 737 -586 -250 O ATOM 646 CB THR X 355 17.159 22.559 50.779 1.00 50.20 C ANISOU 646 CB THR X 355 6627 6857 5586 777 -209 -304 C ATOM 647 OG1 THR X 355 17.156 21.633 51.873 1.00 49.36 O ANISOU 647 OG1 THR X 355 6427 6690 5637 755 -283 -330 O ATOM 648 CG2 THR X 355 18.537 23.197 50.666 1.00 50.60 C ANISOU 648 CG2 THR X 355 6635 6931 5660 800 -4 -290 C ATOM 649 N ASP X 356 14.225 22.471 52.068 1.00 49.11 N ANISOU 649 N ASP X 356 6349 6741 5567 655 -549 -228 N ATOM 650 CA ASP X 356 12.929 21.799 52.133 1.00 49.78 C ANISOU 650 CA ASP X 356 6392 6833 5689 586 -706 -258 C ATOM 651 C ASP X 356 11.817 22.774 52.503 1.00 49.73 C ANISOU 651 C ASP X 356 6260 6906 5728 583 -762 -192 C ATOM 652 O ASP X 356 11.867 23.425 53.546 1.00 48.84 O ANISOU 652 O ASP X 356 6048 6808 5699 581 -681 -135 O ATOM 653 CB ASP X 356 12.973 20.637 53.131 1.00 49.57 C ANISOU 653 CB ASP X 356 6318 6728 5786 500 -717 -278 C ATOM 654 CG ASP X 356 11.763 19.717 53.023 1.00 50.89 C ANISOU 654 CG ASP X 356 6460 6875 6000 388 -863 -323 C ATOM 655 OD1 ASP X 356 10.768 20.076 52.357 1.00 52.04 O ANISOU 655 OD1 ASP X 356 6565 7096 6110 378 -975 -341 O ATOM 656 OD2 ASP X 356 11.807 18.621 53.617 1.00 51.58 O ANISOU 656 OD2 ASP X 356 6566 6859 6170 303 -879 -337 O ATOM 657 N LEU X 357 10.806 22.850 51.644 1.00 51.09 N ANISOU 657 N LEU X 357 6437 7128 5847 595 -915 -215 N ATOM 658 CA LEU X 357 9.710 23.798 51.811 1.00 51.69 C ANISOU 658 CA LEU X 357 6376 7280 5981 636 -993 -167 C ATOM 659 C LEU X 357 8.418 23.138 52.303 1.00 52.68 C ANISOU 659 C LEU X 357 6303 7459 6252 534 -1102 -210 C ATOM 660 O LEU X 357 7.440 23.827 52.604 1.00 53.43 O ANISOU 660 O LEU X 357 6222 7632 6443 571 -1148 -190 O ATOM 661 CB LEU X 357 9.454 24.539 50.492 1.00 53.13 C ANISOU 661 CB LEU X 357 6685 7490 6010 746 -1115 -143 C ATOM 662 CG LEU X 357 10.256 25.789 50.104 1.00 52.88 C ANISOU 662 CG LEU X 357 6802 7423 5867 851 -1007 -47 C ATOM 663 CD1 LEU X 357 11.770 25.598 50.172 1.00 51.76 C ANISOU 663 CD1 LEU X 357 6775 7222 5669 819 -799 -48 C ATOM 664 CD2 LEU X 357 9.848 26.225 48.708 1.00 54.80 C ANISOU 664 CD2 LEU X 357 7217 7684 5918 940 -1167 -15 C ATOM 665 N LYS X 358 8.419 21.809 52.383 1.00 52.99 N ANISOU 665 N LYS X 358 6363 7446 6325 404 -1133 -273 N ATOM 666 CA LYS X 358 7.233 21.056 52.803 1.00 54.31 C ANISOU 666 CA LYS X 358 6347 7647 6640 256 -1221 -312 C ATOM 667 C LYS X 358 7.196 20.793 54.310 1.00 53.53 C ANISOU 667 C LYS X 358 6135 7538 6666 148 -1053 -258 C ATOM 668 O LYS X 358 6.195 20.296 54.836 1.00 55.00 O ANISOU 668 O LYS X 358 6146 7766 6984 4 -1065 -268 O ATOM 669 CB LYS X 358 7.119 19.745 52.017 1.00 55.73 C ANISOU 669 CB LYS X 358 6637 7745 6791 146 -1368 -413 C ATOM 670 CG LYS X 358 6.733 19.945 50.562 1.00 57.46 C ANISOU 670 CG LYS X 358 6943 8009 6878 220 -1582 -485 C ATOM 671 CD LYS X 358 6.825 18.660 49.763 1.00 59.23 C ANISOU 671 CD LYS X 358 7337 8130 7036 125 -1714 -616 C ATOM 672 CE LYS X 358 6.692 18.948 48.274 1.00 61.22 C ANISOU 672 CE LYS X 358 7755 8429 7074 225 -1908 -688 C ATOM 673 NZ LYS X 358 6.798 17.718 47.442 1.00 63.53 N ANISOU 673 NZ LYS X 358 8249 8615 7273 142 -2040 -849 N ATOM 674 N GLN X 359 8.285 21.140 54.993 1.00 51.62 N ANISOU 674 N GLN X 359 5991 7247 6372 208 -899 -201 N ATOM 675 CA GLN X 359 8.399 20.979 56.445 1.00 50.86 C ANISOU 675 CA GLN X 359 5846 7142 6334 127 -751 -141 C ATOM 676 C GLN X 359 7.550 21.992 57.230 1.00 51.10 C ANISOU 676 C GLN X 359 5684 7300 6430 151 -659 -118 C ATOM 677 O GLN X 359 7.249 23.078 56.723 1.00 51.11 O ANISOU 677 O GLN X 359 5622 7366 6431 287 -696 -132 O ATOM 678 CB GLN X 359 9.867 21.074 56.875 1.00 49.25 C ANISOU 678 CB GLN X 359 5801 6856 6054 197 -661 -104 C ATOM 679 CG GLN X 359 10.540 22.405 56.561 1.00 48.03 C ANISOU 679 CG GLN X 359 5675 6736 5837 350 -613 -94 C ATOM 680 CD GLN X 359 11.976 22.459 57.033 1.00 46.77 C ANISOU 680 CD GLN X 359 5618 6509 5641 391 -535 -71 C ATOM 681 OE1 GLN X 359 12.286 22.083 58.162 1.00 46.61 O ANISOU 681 OE1 GLN X 359 5606 6461 5639 336 -491 -37 O ATOM 682 NE2 GLN X 359 12.864 22.936 56.170 1.00 46.22 N ANISOU 682 NE2 GLN X 359 5624 6419 5516 483 -521 -87 N ATOM 683 N PRO X 360 7.157 21.634 58.470 1.00 51.58 N ANISOU 683 N PRO X 360 5671 7387 6539 27 -532 -82 N ATOM 684 CA PRO X 360 6.442 22.568 59.336 1.00 52.10 C ANISOU 684 CA PRO X 360 5570 7575 6650 61 -397 -83 C ATOM 685 C PRO X 360 7.404 23.464 60.119 1.00 50.62 C ANISOU 685 C PRO X 360 5506 7363 6363 167 -284 -58 C ATOM 686 O PRO X 360 8.617 23.403 59.909 1.00 49.22 O ANISOU 686 O PRO X 360 5506 7090 6105 213 -323 -36 O ATOM 687 CB PRO X 360 5.692 21.639 60.290 1.00 53.73 C ANISOU 687 CB PRO X 360 5685 7814 6914 -151 -285 -53 C ATOM 688 CG PRO X 360 6.592 20.464 60.428 1.00 53.19 C ANISOU 688 CG PRO X 360 5845 7589 6773 -257 -323 6 C ATOM 689 CD PRO X 360 7.285 20.302 59.096 1.00 52.18 C ANISOU 689 CD PRO X 360 5833 7370 6622 -154 -502 -39 C ATOM 690 N VAL X 361 6.861 24.292 61.006 1.00 51.27 N ANISOU 690 N VAL X 361 5482 7536 6461 205 -145 -80 N ATOM 691 CA VAL X 361 7.681 25.120 61.888 1.00 50.38 C ANISOU 691 CA VAL X 361 5495 7397 6249 279 -45 -80 C ATOM 692 C VAL X 361 7.459 24.755 63.353 1.00 51.41 C ANISOU 692 C VAL X 361 5648 7581 6304 158 123 -60 C ATOM 693 O VAL X 361 6.368 24.327 63.741 1.00 53.19 O ANISOU 693 O VAL X 361 5722 7901 6584 52 228 -63 O ATOM 694 CB VAL X 361 7.443 26.638 61.675 1.00 50.53 C ANISOU 694 CB VAL X 361 5450 7436 6310 465 -29 -143 C ATOM 695 CG1 VAL X 361 8.034 27.095 60.347 1.00 49.44 C ANISOU 695 CG1 VAL X 361 5393 7213 6178 576 -181 -126 C ATOM 696 CG2 VAL X 361 5.961 26.977 61.761 1.00 52.68 C ANISOU 696 CG2 VAL X 361 5470 7834 6710 505 32 -202 C ATOM 697 N LEU X 362 8.507 24.921 64.154 1.00 50.61 N ANISOU 697 N LEU X 362 5737 7423 6070 165 147 -38 N ATOM 698 CA LEU X 362 8.465 24.606 65.575 1.00 51.79 C ANISOU 698 CA LEU X 362 5982 7612 6081 59 286 -7 C ATOM 699 C LEU X 362 8.118 25.859 66.372 1.00 52.80 C ANISOU 699 C LEU X 362 6082 7823 6156 153 434 -105 C ATOM 700 O LEU X 362 8.682 26.929 66.138 1.00 52.01 O ANISOU 700 O LEU X 362 6021 7672 6067 293 380 -172 O ATOM 701 CB LEU X 362 9.811 24.031 66.034 1.00 50.86 C ANISOU 701 CB LEU X 362 6099 7386 5838 25 182 64 C ATOM 702 CG LEU X 362 10.429 22.895 65.205 1.00 49.78 C ANISOU 702 CG LEU X 362 6020 7130 5762 -10 21 134 C ATOM 703 CD1 LEU X 362 11.896 22.697 65.561 1.00 48.67 C ANISOU 703 CD1 LEU X 362 6057 6892 5543 34 -98 169 C ATOM 704 CD2 LEU X 362 9.652 21.589 65.355 1.00 51.06 C ANISOU 704 CD2 LEU X 362 6182 7273 5944 -185 55 215 C ATOM 705 N VAL X 363 7.184 25.722 67.306 1.00 54.98 N ANISOU 705 N VAL X 363 6296 8215 6376 69 637 -120 N ATOM 706 CA VAL X 363 6.750 26.848 68.129 1.00 56.52 C ANISOU 706 CA VAL X 363 6467 8495 6511 167 815 -242 C ATOM 707 C VAL X 363 7.417 26.786 69.503 1.00 57.47 C ANISOU 707 C VAL X 363 6854 8617 6364 97 892 -230 C ATOM 708 O VAL X 363 7.437 25.731 70.145 1.00 58.41 O ANISOU 708 O VAL X 363 7092 8752 6347 -71 940 -116 O ATOM 709 CB VAL X 363 5.207 26.886 68.283 1.00 58.96 C ANISOU 709 CB VAL X 363 6500 8966 6934 147 1030 -303 C ATOM 710 CG1 VAL X 363 4.761 28.165 68.981 1.00 60.58 C ANISOU 710 CG1 VAL X 363 6664 9243 7111 306 1213 -465 C ATOM 711 CG2 VAL X 363 4.526 26.762 66.924 1.00 58.52 C ANISOU 711 CG2 VAL X 363 6180 8917 7135 195 897 -303 C ATOM 712 N SER X 364 7.968 27.918 69.937 1.00 57.55 N ANISOU 712 N SER X 364 6980 8591 6293 223 884 -343 N ATOM 713 CA SER X 364 8.579 28.035 71.258 1.00 58.95 C ANISOU 713 CA SER X 364 7423 8778 6196 175 928 -367 C ATOM 714 C SER X 364 8.020 29.248 72.005 1.00 61.23 C ANISOU 714 C SER X 364 7717 9135 6411 287 1126 -556 C ATOM 715 O SER X 364 8.170 30.388 71.555 1.00 60.71 O ANISOU 715 O SER X 364 7606 8990 6471 448 1069 -680 O ATOM 716 CB SER X 364 10.103 28.126 71.138 1.00 57.11 C ANISOU 716 CB SER X 364 7373 8409 5918 196 666 -339 C ATOM 717 OG SER X 364 10.730 27.954 72.397 1.00 58.24 O ANISOU 717 OG SER X 364 7780 8565 5783 126 645 -331 O ATOM 718 N GLN X 365 7.368 28.991 73.138 1.00 64.20 N ANISOU 718 N GLN X 365 8167 9645 6578 202 1371 -579 N ATOM 719 CA GLN X 365 6.765 30.047 73.957 1.00 67.01 C ANISOU 719 CA GLN X 365 8542 10082 6834 311 1606 -782 C ATOM 720 C GLN X 365 7.708 30.536 75.059 1.00 68.16 C ANISOU 720 C GLN X 365 9043 10182 6669 309 1547 -869 C ATOM 721 O GLN X 365 8.244 29.726 75.820 1.00 68.82 O ANISOU 721 O GLN X 365 9368 10290 6488 160 1498 -752 O ATOM 722 CB GLN X 365 5.436 29.582 74.567 1.00 70.07 C ANISOU 722 CB GLN X 365 8787 10669 7164 223 1961 -789 C ATOM 723 CG GLN X 365 4.278 29.480 73.575 1.00 70.23 C ANISOU 723 CG GLN X 365 8390 10761 7530 270 2043 -790 C ATOM 724 CD GLN X 365 3.828 30.829 73.018 1.00 70.59 C ANISOU 724 CD GLN X 365 8236 10771 7810 542 2046 -986 C ATOM 725 OE1 GLN X 365 4.073 31.883 73.609 1.00 71.45 O ANISOU 725 OE1 GLN X 365 8501 10833 7813 687 2103 -1160 O ATOM 726 NE2 GLN X 365 3.156 30.793 71.874 1.00 70.03 N ANISOU 726 NE2 GLN X 365 7840 10708 8059 617 1965 -962 N ATOM 727 N PRO X 366 7.905 31.867 75.149 1.00 68.79 N ANISOU 727 N PRO X 366 9173 10182 6782 475 1531 -1077 N ATOM 728 CA PRO X 366 8.833 32.468 76.103 1.00 70.01 C ANISOU 728 CA PRO X 366 9655 10272 6673 474 1430 -1198 C ATOM 729 C PRO X 366 8.163 32.903 77.413 1.00 73.98 C ANISOU 729 C PRO X 366 10326 10904 6879 496 1730 -1380 C ATOM 730 O PRO X 366 7.101 32.380 77.765 1.00 75.90 O ANISOU 730 O PRO X 366 10462 11319 7056 446 2032 -1349 O ATOM 731 CB PRO X 366 9.365 33.688 75.337 1.00 68.60 C ANISOU 731 CB PRO X 366 9427 9901 6737 626 1252 -1326 C ATOM 732 CG PRO X 366 8.304 34.000 74.287 1.00 67.99 C ANISOU 732 CG PRO X 366 9020 9825 6987 768 1371 -1334 C ATOM 733 CD PRO X 366 7.281 32.893 74.295 1.00 68.54 C ANISOU 733 CD PRO X 366 8899 10088 7055 677 1571 -1207 C ATOM 734 N LYS X 367 8.804 33.844 78.114 1.00 75.48 N ANISOU 734 N LYS X 367 10779 11009 6892 555 1649 -1575 N ATOM 735 CA LYS X 367 8.315 34.441 79.371 1.00 79.57 C ANISOU 735 CA LYS X 367 11516 11621 7093 601 1911 -1804 C ATOM 736 C LYS X 367 8.086 33.454 80.517 1.00 82.12 C ANISOU 736 C LYS X 367 12069 12141 6992 427 2093 -1700 C ATOM 737 O LYS X 367 7.141 32.663 80.504 1.00 82.93 O ANISOU 737 O LYS X 367 12003 12401 7104 350 2361 -1573 O ATOM 738 CB LYS X 367 7.070 35.315 79.140 1.00 81.35 C ANISOU 738 CB LYS X 367 11498 11879 7531 806 2225 -2008 C ATOM 739 CG LYS X 367 7.364 36.655 78.480 1.00 80.71 C ANISOU 739 CG LYS X 367 11371 11563 7732 1007 2066 -2190 C ATOM 740 CD LYS X 367 6.111 37.514 78.376 1.00 83.35 C ANISOU 740 CD LYS X 367 11490 11918 8259 1248 2367 -2403 C ATOM 741 CE LYS X 367 6.385 38.820 77.636 1.00 82.78 C ANISOU 741 CE LYS X 367 11396 11566 8489 1453 2187 -2548 C ATOM 742 NZ LYS X 367 7.275 39.746 78.398 1.00 84.21 N ANISOU 742 NZ LYS X 367 11957 11568 8468 1457 2059 -2769 N ATOM 743 N GLY X 378 5.262 37.555 71.051 1.00 73.59 N ANISOU 743 N GLY X 378 8913 10207 8841 1659 1469 -1661 N ATOM 744 CA GLY X 378 5.015 36.500 70.073 1.00 71.57 C ANISOU 744 CA GLY X 378 8431 10055 8704 1561 1363 -1446 C ATOM 745 C GLY X 378 6.021 35.362 70.157 1.00 69.02 C ANISOU 745 C GLY X 378 8253 9773 8198 1294 1247 -1272 C ATOM 746 O GLY X 378 7.166 35.577 70.567 1.00 68.16 O ANISOU 746 O GLY X 378 8406 9552 7937 1210 1141 -1282 O ATOM 747 N PRO X 379 5.604 34.142 69.757 1.00 68.07 N ANISOU 747 N PRO X 379 7952 9801 8109 1163 1249 -1119 N ATOM 748 CA PRO X 379 6.465 32.961 69.853 1.00 66.01 C ANISOU 748 CA PRO X 379 7822 9565 7692 932 1146 -955 C ATOM 749 C PRO X 379 7.571 32.954 68.802 1.00 63.16 C ANISOU 749 C PRO X 379 7545 9041 7410 914 872 -841 C ATOM 750 O PRO X 379 7.454 33.631 67.778 1.00 62.71 O ANISOU 750 O PRO X 379 7406 8880 7538 1050 767 -840 O ATOM 751 CB PRO X 379 5.495 31.806 69.601 1.00 66.46 C ANISOU 751 CB PRO X 379 7638 9792 7821 823 1238 -853 C ATOM 752 CG PRO X 379 4.442 32.387 68.726 1.00 67.42 C ANISOU 752 CG PRO X 379 7467 9933 8215 1008 1239 -913 C ATOM 753 CD PRO X 379 4.300 33.825 69.142 1.00 69.20 C ANISOU 753 CD PRO X 379 7749 10076 8465 1232 1323 -1102 C ATOM 754 N ALA X 380 8.633 32.196 69.063 1.00 61.71 N ANISOU 754 N ALA X 380 7526 8837 7082 755 763 -744 N ATOM 755 CA ALA X 380 9.719 32.025 68.102 1.00 59.36 C ANISOU 755 CA ALA X 380 7277 8416 6859 722 541 -639 C ATOM 756 C ALA X 380 9.467 30.794 67.238 1.00 58.10 C ANISOU 756 C ALA X 380 6985 8314 6774 643 478 -493 C ATOM 757 O ALA X 380 9.434 29.669 67.740 1.00 58.30 O ANISOU 757 O ALA X 380 7036 8416 6696 507 507 -416 O ATOM 758 CB ALA X 380 11.062 31.918 68.820 1.00 58.88 C ANISOU 758 CB ALA X 380 7433 8297 6641 621 435 -637 C HETATM 759 N MSE X 381 9.270 31.017 65.943 1.00 57.20 N ANISOU 759 N MSE X 381 6758 8147 6827 726 383 -454 N HETATM 760 CA MSE X 381 9.057 29.923 65.003 1.00 56.27 C ANISOU 760 CA MSE X 381 6537 8065 6776 659 297 -344 C HETATM 761 C MSE X 381 10.401 29.415 64.516 1.00 54.00 C ANISOU 761 C MSE X 381 6379 7685 6450 592 154 -264 C HETATM 762 O MSE X 381 11.221 30.187 64.020 1.00 53.22 O ANISOU 762 O MSE X 381 6354 7483 6383 649 85 -274 O HETATM 763 CB MSE X 381 8.190 30.361 63.820 1.00 57.05 C ANISOU 763 CB MSE X 381 6471 8164 7038 785 238 -347 C HETATM 764 CG MSE X 381 6.896 31.062 64.207 1.00 60.89 C ANISOU 764 CG MSE X 381 6786 8733 7617 907 362 -448 C HETATM 765 SE MSE X 381 5.773 30.003 65.396 1.00 67.43 SE ANISOU 765 SE MSE X 381 7443 9773 8401 752 589 -473 SE HETATM 766 CE MSE X 381 4.471 29.352 64.092 1.00 67.38 C ANISOU 766 CE MSE X 381 7107 9865 8627 756 475 -436 C ATOM 767 N LEU X 382 10.619 28.113 64.664 1.00 53.11 N ANISOU 767 N LEU X 382 6289 7602 6285 469 123 -187 N ATOM 768 CA LEU X 382 11.905 27.498 64.353 1.00 51.34 C ANISOU 768 CA LEU X 382 6169 7299 6036 425 0 -128 C ATOM 769 C LEU X 382 11.785 26.497 63.213 1.00 50.42 C ANISOU 769 C LEU X 382 5999 7166 5991 399 -80 -67 C ATOM 770 O LEU X 382 10.783 25.794 63.100 1.00 51.08 O ANISOU 770 O LEU X 382 5997 7304 6104 341 -55 -46 O ATOM 771 CB LEU X 382 12.467 26.808 65.596 1.00 51.81 C ANISOU 771 CB LEU X 382 6357 7367 5960 331 -4 -96 C ATOM 772 CG LEU X 382 12.482 27.627 66.888 1.00 52.63 C ANISOU 772 CG LEU X 382 6555 7506 5936 335 74 -171 C ATOM 773 CD1 LEU X 382 12.491 26.706 68.088 1.00 53.69 C ANISOU 773 CD1 LEU X 382 6820 7683 5893 226 97 -110 C ATOM 774 CD2 LEU X 382 13.661 28.590 66.925 1.00 52.00 C ANISOU 774 CD2 LEU X 382 6546 7344 5867 384 -18 -236 C ATOM 775 N ILE X 383 12.814 26.438 62.373 1.00 49.12 N ANISOU 775 N ILE X 383 5880 6927 5855 433 -168 -51 N ATOM 776 CA ILE X 383 12.839 25.509 61.245 1.00 48.46 C ANISOU 776 CA ILE X 383 5784 6816 5812 423 -242 -21 C ATOM 777 C ILE X 383 13.622 24.241 61.605 1.00 48.25 C ANISOU 777 C ILE X 383 5835 6733 5761 362 -299 16 C ATOM 778 O ILE X 383 14.795 24.318 61.969 1.00 47.98 O ANISOU 778 O ILE X 383 5854 6658 5717 385 -332 16 O ATOM 779 CB ILE X 383 13.389 26.181 59.952 1.00 47.93 C ANISOU 779 CB ILE X 383 5730 6707 5772 508 -271 -32 C ATOM 780 CG1 ILE X 383 12.308 27.036 59.283 1.00 48.43 C ANISOU 780 CG1 ILE X 383 5732 6803 5863 580 -271 -42 C ATOM 781 CG2 ILE X 383 13.864 25.137 58.946 1.00 47.77 C ANISOU 781 CG2 ILE X 383 5749 6650 5752 502 -333 -24 C ATOM 782 CD1 ILE X 383 12.061 28.381 59.931 1.00 48.63 C ANISOU 782 CD1 ILE X 383 5746 6822 5908 643 -206 -71 C ATOM 783 N PRO X 384 12.960 23.071 61.515 1.00 48.69 N ANISOU 783 N PRO X 384 5894 6776 5829 283 -325 47 N ATOM 784 CA PRO X 384 13.535 21.755 61.804 1.00 49.05 C ANISOU 784 CA PRO X 384 6040 6727 5868 234 -394 93 C ATOM 785 C PRO X 384 14.892 21.526 61.141 1.00 48.51 C ANISOU 785 C PRO X 384 6013 6581 5837 331 -466 65 C ATOM 786 O PRO X 384 15.802 20.987 61.770 1.00 48.80 O ANISOU 786 O PRO X 384 6116 6552 5870 351 -527 94 O ATOM 787 CB PRO X 384 12.501 20.792 61.221 1.00 49.81 C ANISOU 787 CB PRO X 384 6113 6800 6012 142 -417 98 C ATOM 788 CG PRO X 384 11.223 21.511 61.340 1.00 50.25 C ANISOU 788 CG PRO X 384 6031 6978 6083 103 -336 81 C ATOM 789 CD PRO X 384 11.526 22.975 61.189 1.00 49.41 C ANISOU 789 CD PRO X 384 5877 6933 5961 230 -297 37 C ATOM 790 N GLU X 385 15.010 21.949 59.885 1.00 48.10 N ANISOU 790 N GLU X 385 5918 6543 5813 397 -455 10 N ATOM 791 CA GLU X 385 16.233 21.813 59.099 1.00 48.12 C ANISOU 791 CA GLU X 385 5935 6498 5848 486 -467 -32 C ATOM 792 C GLU X 385 17.386 22.614 59.704 1.00 48.03 C ANISOU 792 C GLU X 385 5882 6505 5860 526 -447 -34 C ATOM 793 O GLU X 385 18.556 22.313 59.458 1.00 48.50 O ANISOU 793 O GLU X 385 5916 6531 5981 589 -462 -66 O ATOM 794 CB GLU X 385 15.970 22.275 57.662 1.00 47.97 C ANISOU 794 CB GLU X 385 5911 6512 5803 528 -431 -77 C ATOM 795 CG GLU X 385 17.005 21.831 56.632 1.00 48.65 C ANISOU 795 CG GLU X 385 6032 6556 5894 605 -407 -137 C ATOM 796 CD GLU X 385 16.714 22.347 55.225 1.00 49.20 C ANISOU 796 CD GLU X 385 6148 6667 5877 637 -363 -166 C ATOM 797 OE1 GLU X 385 15.533 22.605 54.901 1.00 49.44 O ANISOU 797 OE1 GLU X 385 6192 6734 5858 606 -417 -150 O ATOM 798 OE2 GLU X 385 17.672 22.488 54.436 1.00 49.70 O ANISOU 798 OE2 GLU X 385 6233 6733 5917 694 -275 -205 O ATOM 799 N LEU X 386 17.049 23.623 60.501 1.00 47.90 N ANISOU 799 N LEU X 386 5846 6543 5811 491 -415 -18 N ATOM 800 CA LEU X 386 18.041 24.537 61.059 1.00 48.11 C ANISOU 800 CA LEU X 386 5836 6579 5862 503 -412 -39 C ATOM 801 C LEU X 386 18.285 24.321 62.553 1.00 48.83 C ANISOU 801 C LEU X 386 5974 6672 5906 468 -492 -18 C ATOM 802 O LEU X 386 18.967 25.122 63.197 1.00 49.17 O ANISOU 802 O LEU X 386 5999 6729 5953 460 -520 -51 O ATOM 803 CB LEU X 386 17.626 25.989 60.795 1.00 47.75 C ANISOU 803 CB LEU X 386 5773 6561 5806 498 -329 -58 C ATOM 804 CG LEU X 386 17.402 26.446 59.348 1.00 47.61 C ANISOU 804 CG LEU X 386 5753 6537 5797 535 -264 -55 C ATOM 805 CD1 LEU X 386 16.954 27.896 59.326 1.00 47.92 C ANISOU 805 CD1 LEU X 386 5808 6564 5832 543 -212 -53 C ATOM 806 CD2 LEU X 386 18.644 26.256 58.478 1.00 47.91 C ANISOU 806 CD2 LEU X 386 5762 6555 5884 556 -226 -73 C ATOM 807 N CYS X 387 17.735 23.236 63.095 1.00 49.44 N ANISOU 807 N CYS X 387 6131 6725 5927 436 -538 38 N ATOM 808 CA CYS X 387 17.850 22.944 64.521 1.00 50.61 C ANISOU 808 CA CYS X 387 6380 6872 5977 395 -612 86 C ATOM 809 C CYS X 387 18.419 21.553 64.783 1.00 51.85 C ANISOU 809 C CYS X 387 6616 6933 6149 423 -744 152 C ATOM 810 O CYS X 387 17.976 20.573 64.186 1.00 51.99 O ANISOU 810 O CYS X 387 6665 6879 6206 415 -738 182 O ATOM 811 CB CYS X 387 16.489 23.077 65.207 1.00 50.83 C ANISOU 811 CB CYS X 387 6469 6957 5885 306 -509 119 C ATOM 812 SG CYS X 387 15.665 24.666 64.969 1.00 50.26 S ANISOU 812 SG CYS X 387 6307 6972 5814 316 -364 33 S ATOM 813 N TYR X 388 19.402 21.479 65.678 1.00 53.16 N ANISOU 813 N TYR X 388 6824 7083 6292 462 -886 168 N ATOM 814 CA TYR X 388 19.939 20.204 66.145 1.00 54.95 C ANISOU 814 CA TYR X 388 7158 7198 6520 512 -1049 249 C ATOM 815 C TYR X 388 19.107 19.669 67.306 1.00 56.40 C ANISOU 815 C TYR X 388 7559 7359 6509 407 -1058 373 C ATOM 816 O TYR X 388 18.151 20.310 67.740 1.00 56.17 O ANISOU 816 O TYR X 388 7564 7424 6354 302 -916 373 O ATOM 817 CB TYR X 388 21.395 20.354 66.584 1.00 56.08 C ANISOU 817 CB TYR X 388 7231 7340 6735 617 -1237 214 C ATOM 818 CG TYR X 388 22.358 20.723 65.482 1.00 55.64 C ANISOU 818 CG TYR X 388 6943 7305 6890 710 -1208 101 C ATOM 819 CD1 TYR X 388 22.513 19.910 64.359 1.00 55.43 C ANISOU 819 CD1 TYR X 388 6860 7204 6994 795 -1159 74 C ATOM 820 CD2 TYR X 388 23.136 21.876 65.574 1.00 55.93 C ANISOU 820 CD2 TYR X 388 6828 7431 6989 699 -1218 14 C ATOM 821 CE1 TYR X 388 23.406 20.246 63.348 1.00 55.60 C ANISOU 821 CE1 TYR X 388 6678 7262 7183 874 -1089 -32 C ATOM 822 CE2 TYR X 388 24.035 22.219 64.571 1.00 55.96 C ANISOU 822 CE2 TYR X 388 6612 7461 7186 754 -1154 -77 C ATOM 823 CZ TYR X 388 24.163 21.402 63.462 1.00 55.75 C ANISOU 823 CZ TYR X 388 6532 7382 7266 845 -1075 -97 C ATOM 824 OH TYR X 388 25.052 21.741 62.469 1.00 56.32 O ANISOU 824 OH TYR X 388 6396 7497 7504 893 -969 -190 O ATOM 825 N LEU X 389 19.485 18.499 67.815 1.00 58.43 N ANISOU 825 N LEU X 389 7971 7485 6742 441 -1213 481 N ATOM 826 CA LEU X 389 18.735 17.842 68.885 1.00 60.40 C ANISOU 826 CA LEU X 389 8470 7687 6790 321 -1209 633 C ATOM 827 C LEU X 389 19.493 17.768 70.211 1.00 62.77 C ANISOU 827 C LEU X 389 8953 7977 6919 360 -1413 716 C ATOM 828 O LEU X 389 20.722 17.876 70.250 1.00 63.38 O ANISOU 828 O LEU X 389 8951 8040 7090 506 -1621 668 O ATOM 829 CB LEU X 389 18.297 16.441 68.446 1.00 61.25 C ANISOU 829 CB LEU X 389 8689 7610 6972 286 -1219 730 C ATOM 830 CG LEU X 389 17.198 16.363 67.384 1.00 59.83 C ANISOU 830 CG LEU X 389 8396 7443 6893 185 -1028 673 C ATOM 831 CD1 LEU X 389 17.278 15.040 66.648 1.00 60.74 C ANISOU 831 CD1 LEU X 389 8581 7343 7151 214 -1109 698 C ATOM 832 CD2 LEU X 389 15.815 16.570 67.996 1.00 60.12 C ANISOU 832 CD2 LEU X 389 8487 7573 6781 -20 -834 738 C ATOM 833 N THR X 390 18.737 17.590 71.293 1.00 64.56 N ANISOU 833 N THR X 390 9418 8221 6890 224 -1350 838 N ATOM 834 CA THR X 390 19.281 17.508 72.647 1.00 67.29 C ANISOU 834 CA THR X 390 10008 8565 6991 238 -1539 936 C ATOM 835 C THR X 390 18.335 16.670 73.513 1.00 69.72 C ANISOU 835 C THR X 390 10633 8806 7050 73 -1439 1137 C ATOM 836 O THR X 390 17.170 16.475 73.155 1.00 69.18 O ANISOU 836 O THR X 390 10534 8749 7001 -78 -1182 1160 O ATOM 837 CB THR X 390 19.435 18.921 73.281 1.00 66.98 C ANISOU 837 CB THR X 390 9926 8718 6805 223 -1513 802 C ATOM 838 OG1 THR X 390 19.949 19.843 72.312 1.00 64.52 O ANISOU 838 OG1 THR X 390 9302 8471 6739 307 -1495 617 O ATOM 839 CG2 THR X 390 20.368 18.889 74.487 1.00 69.90 C ANISOU 839 CG2 THR X 390 10506 9085 6966 286 -1806 856 C ATOM 840 N GLY X 391 18.841 16.169 74.639 1.00 72.77 N ANISOU 840 N GLY X 391 11320 9122 7206 94 -1649 1288 N ATOM 841 CA GLY X 391 17.986 15.610 75.684 1.00 75.74 C ANISOU 841 CA GLY X 391 12045 9470 7259 -90 -1526 1488 C ATOM 842 C GLY X 391 17.365 16.740 76.492 1.00 76.20 C ANISOU 842 C GLY X 391 12149 9764 7037 -203 -1311 1401 C ATOM 843 O GLY X 391 18.030 17.745 76.766 1.00 75.70 O ANISOU 843 O GLY X 391 12010 9825 6925 -104 -1430 1248 O ATOM 844 N LEU X 392 16.093 16.581 76.869 1.00 77.46 N ANISOU 844 N LEU X 392 12420 9982 7029 -415 -987 1483 N ATOM 845 CA LEU X 392 15.355 17.617 77.609 1.00 78.22 C ANISOU 845 CA LEU X 392 12546 10305 6867 -515 -719 1379 C ATOM 846 C LEU X 392 14.133 17.105 78.375 1.00 81.18 C ANISOU 846 C LEU X 392 13146 10719 6976 -758 -394 1540 C ATOM 847 O LEU X 392 13.709 15.960 78.197 1.00 82.36 O ANISOU 847 O LEU X 392 13393 10712 7187 -887 -346 1733 O ATOM 848 CB LEU X 392 14.910 18.724 76.658 1.00 74.94 C ANISOU 848 CB LEU X 392 11732 10028 6711 -471 -531 1133 C ATOM 849 N THR X 393 13.576 17.974 79.222 1.00 82.71 N ANISOU 849 N THR X 393 13422 11119 6884 -827 -157 1448 N ATOM 850 CA THR X 393 12.352 17.685 79.978 1.00 85.85 C ANISOU 850 CA THR X 393 13986 11612 7021 -1064 231 1560 C ATOM 851 C THR X 393 11.156 18.415 79.362 1.00 84.32 C ANISOU 851 C THR X 393 13402 11593 7042 -1126 612 1370 C ATOM 852 O THR X 393 11.196 19.629 79.146 1.00 82.54 O ANISOU 852 O THR X 393 12967 11503 6889 -989 650 1125 O ATOM 853 CB THR X 393 12.487 18.076 81.476 1.00 89.52 C ANISOU 853 CB THR X 393 14857 12200 6956 -1100 271 1588 C ATOM 854 OG1 THR X 393 13.663 17.473 82.031 1.00 91.18 O ANISOU 854 OG1 THR X 393 15416 12253 6973 -1009 -149 1754 O ATOM 855 CG2 THR X 393 11.264 17.618 82.278 1.00 93.33 C ANISOU 855 CG2 THR X 393 15543 12772 7145 -1368 705 1739 C TER 856 THR X 393 ATOM 857 O5' G A 1 28.804 30.946 42.643 1.00 70.27 O ANISOU 857 O5' G A 1 8860 9029 8809 -153 1033 -245 O ATOM 858 C5' G A 1 27.708 30.051 42.816 1.00 70.05 C ANISOU 858 C5' G A 1 8803 9099 8711 -191 928 -369 C ATOM 859 C4' G A 1 28.172 28.683 43.290 1.00 69.64 C ANISOU 859 C4' G A 1 8716 8969 8775 -293 913 -471 C ATOM 860 O4' G A 1 29.212 28.172 42.418 1.00 70.45 O ANISOU 860 O4' G A 1 8827 9054 8886 -279 993 -486 O ATOM 861 C3' G A 1 28.807 28.641 44.673 1.00 68.51 C ANISOU 861 C3' G A 1 8562 8667 8801 -364 897 -432 C ATOM 862 O3' G A 1 27.803 28.616 45.683 1.00 67.60 O ANISOU 862 O3' G A 1 8437 8552 8693 -393 823 -450 O ATOM 863 C2' G A 1 29.602 27.340 44.608 1.00 68.73 C ANISOU 863 C2' G A 1 8570 8631 8913 -416 930 -504 C ATOM 864 O2' G A 1 28.820 26.185 44.845 1.00 68.83 O ANISOU 864 O2' G A 1 8554 8663 8933 -465 904 -612 O ATOM 865 C1' G A 1 30.089 27.340 43.160 1.00 69.90 C ANISOU 865 C1' G A 1 8732 8846 8978 -365 1004 -512 C ATOM 866 N9 G A 1 31.471 27.799 42.986 1.00 70.29 N ANISOU 866 N9 G A 1 8792 8792 9124 -350 1089 -431 N ATOM 867 C8 G A 1 31.897 28.917 42.308 1.00 70.95 C ANISOU 867 C8 G A 1 8903 8872 9182 -274 1177 -330 C ATOM 868 N7 G A 1 33.193 29.072 42.314 1.00 71.26 N ANISOU 868 N7 G A 1 8923 8781 9368 -287 1261 -291 N ATOM 869 C5 G A 1 33.664 27.987 43.041 1.00 70.64 C ANISOU 869 C5 G A 1 8806 8633 9398 -366 1206 -371 C ATOM 870 C6 G A 1 34.991 27.616 43.383 1.00 70.60 C ANISOU 870 C6 G A 1 8758 8495 9570 -402 1242 -385 C ATOM 871 O6 G A 1 36.047 28.199 43.100 1.00 70.95 O ANISOU 871 O6 G A 1 8776 8443 9738 -385 1335 -343 O ATOM 872 N1 G A 1 35.033 26.439 44.135 1.00 70.19 N ANISOU 872 N1 G A 1 8686 8418 9564 -453 1172 -457 N ATOM 873 C2 G A 1 33.925 25.711 44.510 1.00 69.89 C ANISOU 873 C2 G A 1 8665 8450 9440 -477 1104 -507 C ATOM 874 N2 G A 1 34.146 24.604 45.232 1.00 69.56 N ANISOU 874 N2 G A 1 8607 8348 9474 -509 1083 -552 N ATOM 875 N3 G A 1 32.679 26.049 44.195 1.00 69.96 N ANISOU 875 N3 G A 1 8698 8572 9311 -460 1073 -514 N ATOM 876 C4 G A 1 32.617 27.193 43.461 1.00 70.23 C ANISOU 876 C4 G A 1 8756 8656 9271 -401 1113 -445 C ATOM 877 P C A 2 27.881 29.598 46.949 1.00 66.60 P ANISOU 877 P C A 2 8322 8344 8635 -390 784 -366 P ATOM 878 OP1 C A 2 26.502 29.799 47.451 1.00 66.37 O ANISOU 878 OP1 C A 2 8295 8373 8548 -391 728 -378 O ATOM 879 OP2 C A 2 28.701 30.777 46.587 1.00 67.03 O ANISOU 879 OP2 C A 2 8382 8363 8723 -348 834 -282 O ATOM 880 O5' C A 2 28.708 28.741 48.015 1.00 65.67 O ANISOU 880 O5' C A 2 8198 8110 8642 -425 773 -388 O ATOM 881 C5' C A 2 28.126 27.586 48.607 1.00 64.76 C ANISOU 881 C5' C A 2 8085 7977 8543 -454 767 -440 C ATOM 882 C4' C A 2 29.192 26.576 48.978 1.00 64.32 C ANISOU 882 C4' C A 2 8027 7829 8582 -461 799 -457 C ATOM 883 O4' C A 2 30.117 26.398 47.878 1.00 64.47 O ANISOU 883 O4' C A 2 8025 7851 8617 -474 848 -478 O ATOM 884 C3' C A 2 30.098 26.995 50.124 1.00 63.88 C ANISOU 884 C3' C A 2 7980 7699 8592 -412 752 -411 C ATOM 885 O3' C A 2 29.474 26.788 51.380 1.00 63.24 O ANISOU 885 O3' C A 2 7935 7596 8496 -373 721 -388 O ATOM 886 C2' C A 2 31.291 26.069 49.924 1.00 64.24 C ANISOU 886 C2' C A 2 8007 7681 8718 -414 792 -437 C ATOM 887 O2' C A 2 31.085 24.773 50.457 1.00 64.34 O ANISOU 887 O2' C A 2 8042 7648 8755 -406 833 -449 O ATOM 888 C1' C A 2 31.387 26.028 48.398 1.00 64.60 C ANISOU 888 C1' C A 2 8033 7773 8738 -460 855 -467 C ATOM 889 N1 C A 2 32.471 26.897 47.810 1.00 64.82 N ANISOU 889 N1 C A 2 8034 7776 8817 -447 876 -442 N ATOM 890 C2 C A 2 33.819 26.485 47.853 1.00 65.14 C ANISOU 890 C2 C A 2 8041 7733 8973 -443 901 -459 C ATOM 891 O2 C A 2 34.127 25.406 48.376 1.00 65.12 O ANISOU 891 O2 C A 2 8040 7689 9011 -439 897 -485 O ATOM 892 N3 C A 2 34.770 27.291 47.310 1.00 65.61 N ANISOU 892 N3 C A 2 8064 7749 9116 -436 947 -444 N ATOM 893 C4 C A 2 34.426 28.454 46.746 1.00 65.79 C ANISOU 893 C4 C A 2 8093 7801 9104 -423 983 -396 C ATOM 894 N4 C A 2 35.399 29.211 46.228 1.00 66.36 N ANISOU 894 N4 C A 2 8124 7798 9291 -411 1067 -373 N ATOM 895 C5 C A 2 33.067 28.891 46.689 1.00 65.46 C ANISOU 895 C5 C A 2 8094 7855 8921 -414 952 -366 C ATOM 896 C6 C A 2 32.138 28.091 47.226 1.00 64.94 C ANISOU 896 C6 C A 2 8054 7839 8782 -431 890 -399 C ATOM 897 P G A 3 29.636 27.885 52.532 1.00 62.65 P ANISOU 897 P G A 3 7872 7515 8416 -304 632 -354 P ATOM 898 OP1 G A 3 29.750 27.160 53.820 1.00 62.92 O ANISOU 898 OP1 G A 3 7951 7508 8446 -219 619 -336 O ATOM 899 OP2 G A 3 28.552 28.874 52.339 1.00 62.37 O ANISOU 899 OP2 G A 3 7840 7537 8318 -327 615 -333 O ATOM 900 O5' G A 3 31.021 28.615 52.173 1.00 62.56 O ANISOU 900 O5' G A 3 7802 7474 8492 -298 607 -378 O ATOM 901 C5' G A 3 32.038 28.838 53.148 1.00 62.06 C ANISOU 901 C5' G A 3 7709 7371 8497 -224 533 -412 C ATOM 902 C4' G A 3 33.109 27.760 53.097 1.00 61.66 C ANISOU 902 C4' G A 3 7642 7276 8508 -201 553 -440 C ATOM 903 O4' G A 3 33.439 27.434 51.724 1.00 61.29 O ANISOU 903 O4' G A 3 7571 7214 8502 -284 644 -443 O ATOM 904 C3' G A 3 34.436 28.168 53.720 1.00 61.87 C ANISOU 904 C3' G A 3 7595 7270 8640 -129 471 -511 C ATOM 905 O3' G A 3 34.432 27.878 55.110 1.00 62.02 O ANISOU 905 O3' G A 3 7650 7317 8598 0 381 -522 O ATOM 906 C2' G A 3 35.451 27.326 52.952 1.00 61.90 C ANISOU 906 C2' G A 3 7564 7224 8731 -160 534 -531 C ATOM 907 O2' G A 3 35.581 26.000 53.429 1.00 61.93 O ANISOU 907 O2' G A 3 7615 7219 8696 -99 547 -510 O ATOM 908 C1' G A 3 34.842 27.344 51.553 1.00 61.43 C ANISOU 908 C1' G A 3 7524 7174 8641 -270 645 -488 C ATOM 909 N9 G A 3 35.290 28.478 50.743 1.00 61.37 N ANISOU 909 N9 G A 3 7457 7141 8719 -313 685 -498 N ATOM 910 C8 G A 3 34.505 29.478 50.216 1.00 61.15 C ANISOU 910 C8 G A 3 7444 7145 8643 -343 719 -453 C ATOM 911 N7 G A 3 35.171 30.368 49.535 1.00 61.47 N ANISOU 911 N7 G A 3 7429 7131 8795 -358 791 -452 N ATOM 912 C5 G A 3 36.487 29.934 49.614 1.00 61.85 C ANISOU 912 C5 G A 3 7409 7103 8987 -351 795 -515 C ATOM 913 C6 G A 3 37.665 30.498 49.065 1.00 62.49 C ANISOU 913 C6 G A 3 7400 7082 9260 -364 880 -548 C ATOM 914 O6 G A 3 37.770 31.524 48.381 1.00 62.73 O ANISOU 914 O6 G A 3 7403 7058 9372 -379 991 -511 O ATOM 915 N1 G A 3 38.799 29.747 49.379 1.00 63.02 N ANISOU 915 N1 G A 3 7404 7097 9442 -348 847 -626 N ATOM 916 C2 G A 3 38.793 28.593 50.132 1.00 62.74 C ANISOU 916 C2 G A 3 7403 7107 9327 -307 751 -650 C ATOM 917 N2 G A 3 39.977 27.999 50.336 1.00 63.21 N ANISOU 917 N2 G A 3 7392 7113 9511 -278 731 -721 N ATOM 918 N3 G A 3 37.694 28.054 50.647 1.00 62.15 N ANISOU 918 N3 G A 3 7423 7115 9076 -287 697 -602 N ATOM 919 C4 G A 3 36.579 28.773 50.353 1.00 61.78 C ANISOU 919 C4 G A 3 7425 7116 8930 -319 719 -544 C ATOM 920 P A A 4 35.130 28.896 56.127 1.00 62.14 P ANISOU 920 P A A 4 7591 7353 8667 100 239 -626 P ATOM 921 OP1 A A 4 34.748 28.513 57.507 1.00 62.65 O ANISOU 921 OP1 A A 4 7733 7477 8594 258 161 -610 O ATOM 922 OP2 A A 4 34.884 30.279 55.652 1.00 61.97 O ANISOU 922 OP2 A A 4 7506 7314 8723 13 247 -655 O ATOM 923 O5' A A 4 36.671 28.553 55.898 1.00 62.45 O ANISOU 923 O5' A A 4 7528 7346 8851 125 215 -717 O ATOM 924 C5' A A 4 37.205 27.310 56.330 1.00 62.29 C ANISOU 924 C5' A A 4 7544 7334 8790 226 204 -703 C ATOM 925 C4' A A 4 38.708 27.341 56.168 1.00 62.84 C ANISOU 925 C4' A A 4 7483 7365 9028 251 155 -823 C ATOM 926 O4' A A 4 39.022 27.390 54.754 1.00 61.99 O ANISOU 926 O4' A A 4 7331 7176 9046 93 283 -805 O ATOM 927 C3' A A 4 39.377 28.580 56.744 1.00 63.72 C ANISOU 927 C3' A A 4 7458 7488 9264 300 24 -988 C ATOM 928 O3' A A 4 39.619 28.422 58.146 1.00 65.15 O ANISOU 928 O3' A A 4 7642 7763 9346 506 -137 -1065 O ATOM 929 C2' A A 4 40.646 28.668 55.898 1.00 64.00 C ANISOU 929 C2' A A 4 7354 7431 9531 227 70 -1078 C ATOM 930 O2' A A 4 41.667 27.775 56.308 1.00 65.09 O ANISOU 930 O2' A A 4 7449 7582 9697 342 3 -1141 O ATOM 931 C1' A A 4 40.114 28.262 54.525 1.00 62.37 C ANISOU 931 C1' A A 4 7226 7166 9304 70 255 -933 C ATOM 932 N9 A A 4 39.673 29.379 53.684 1.00 61.24 N ANISOU 932 N9 A A 4 7059 6976 9233 -52 349 -908 N ATOM 933 C8 A A 4 38.384 29.714 53.368 1.00 60.13 C ANISOU 933 C8 A A 4 7017 6871 8955 -109 404 -800 C ATOM 934 N7 A A 4 38.275 30.763 52.588 1.00 59.94 N ANISOU 934 N7 A A 4 6953 6796 9026 -189 495 -785 N ATOM 935 C5 A A 4 39.587 31.150 52.373 1.00 60.79 C ANISOU 935 C5 A A 4 6921 6807 9369 -196 519 -892 C ATOM 936 C6 A A 4 40.161 32.204 51.627 1.00 61.22 C ANISOU 936 C6 A A 4 6872 6745 9642 -257 644 -922 C ATOM 937 N6 A A 4 39.439 33.091 50.936 1.00 60.86 N ANISOU 937 N6 A A 4 6866 6676 9579 -308 764 -825 N ATOM 938 N1 A A 4 41.509 32.314 51.618 1.00 62.36 N ANISOU 938 N1 A A 4 6867 6790 10037 -252 656 -1051 N ATOM 939 C2 A A 4 42.237 31.428 52.313 1.00 62.83 C ANISOU 939 C2 A A 4 6884 6885 10102 -180 527 -1148 C ATOM 940 N3 A A 4 41.810 30.398 53.048 1.00 62.56 N ANISOU 940 N3 A A 4 6951 6966 9850 -99 404 -1114 N ATOM 941 C4 A A 4 40.464 30.309 53.040 1.00 61.57 C ANISOU 941 C4 A A 4 6973 6918 9501 -117 418 -981 C ATOM 942 P A A 5 39.502 29.673 59.146 1.00 65.97 P ANISOU 942 P A A 5 7675 7934 9456 592 -290 -1210 P ATOM 943 OP1 A A 5 39.491 29.159 60.536 1.00 67.09 O ANISOU 943 OP1 A A 5 7886 8201 9401 838 -430 -1234 O ATOM 944 OP2 A A 5 38.401 30.547 58.681 1.00 64.75 O ANISOU 944 OP2 A A 5 7562 7746 9291 450 -204 -1133 O ATOM 945 O5' A A 5 40.883 30.443 58.895 1.00 67.17 O ANISOU 945 O5' A A 5 7600 8024 9897 561 -353 -1433 O ATOM 946 C5' A A 5 42.132 29.797 59.146 1.00 68.20 C ANISOU 946 C5' A A 5 7635 8170 10107 674 -439 -1550 C ATOM 947 C4' A A 5 43.296 30.543 58.514 1.00 68.94 C ANISOU 947 C4' A A 5 7505 8150 10538 573 -422 -1734 C ATOM 948 O4' A A 5 43.174 30.584 57.067 1.00 67.66 O ANISOU 948 O4' A A 5 7363 7849 10494 362 -202 -1601 O ATOM 949 C3' A A 5 43.426 32.009 58.895 1.00 69.67 C ANISOU 949 C3' A A 5 7433 8219 10818 554 -495 -1939 C ATOM 950 O3' A A 5 43.963 32.146 60.198 1.00 71.31 O ANISOU 950 O3' A A 5 7541 8554 10999 765 -732 -2165 O ATOM 951 C2' A A 5 44.355 32.503 57.790 1.00 70.14 C ANISOU 951 C2' A A 5 7321 8100 11226 392 -352 -2016 C ATOM 952 O2' A A 5 45.708 32.125 57.969 1.00 71.71 O ANISOU 952 O2' A A 5 7352 8285 11607 471 -440 -2204 O ATOM 953 C1' A A 5 43.743 31.790 56.583 1.00 68.34 C ANISOU 953 C1' A A 5 7269 7813 10882 256 -142 -1740 C ATOM 954 N9 A A 5 42.709 32.590 55.920 1.00 67.15 N ANISOU 954 N9 A A 5 7197 7609 10707 123 2 -1603 N ATOM 955 C8 A A 5 41.351 32.463 56.051 1.00 65.77 C ANISOU 955 C8 A A 5 7203 7515 10268 118 14 -1434 C ATOM 956 N7 A A 5 40.661 33.325 55.345 1.00 65.11 N ANISOU 956 N7 A A 5 7145 7370 10223 3 147 -1346 N ATOM 957 C5 A A 5 41.630 34.075 54.703 1.00 66.11 C ANISOU 957 C5 A A 5 7106 7352 10661 -68 252 -1448 C ATOM 958 C6 A A 5 41.554 35.158 53.800 1.00 66.26 C ANISOU 958 C6 A A 5 7073 7236 10865 -175 443 -1405 C ATOM 959 N6 A A 5 40.396 35.682 53.382 1.00 65.42 N ANISOU 959 N6 A A 5 7083 7146 10626 -223 536 -1247 N ATOM 960 N1 A A 5 42.713 35.687 53.346 1.00 67.51 N ANISOU 960 N1 A A 5 7051 7237 11361 -219 549 -1527 N ATOM 961 C2 A A 5 43.874 35.165 53.765 1.00 68.54 C ANISOU 961 C2 A A 5 7050 7358 11635 -166 446 -1702 C ATOM 962 N3 A A 5 44.069 34.149 54.608 1.00 68.62 N ANISOU 962 N3 A A 5 7092 7505 11475 -54 245 -1761 N ATOM 963 C4 A A 5 42.900 33.641 55.047 1.00 67.35 C ANISOU 963 C4 A A 5 7125 7489 10976 -6 166 -1617 C ATOM 964 P U A 6 43.216 33.066 61.277 1.00 71.95 P ANISOU 964 P U A 6 7629 8740 10966 863 -868 -2265 P ATOM 965 OP1 U A 6 43.467 32.473 62.610 1.00 73.37 O ANISOU 965 OP1 U A 6 7842 9114 10920 1151 -1094 -2367 O ATOM 966 OP2 U A 6 41.827 33.321 60.834 1.00 69.89 O ANISOU 966 OP2 U A 6 7546 8445 10563 730 -718 -2028 O ATOM 967 O5' U A 6 44.002 34.451 61.166 1.00 73.43 O ANISOU 967 O5' U A 6 7535 8819 11544 776 -892 -2559 O ATOM 968 C5' U A 6 45.423 34.470 61.149 1.00 75.50 C ANISOU 968 C5' U A 6 7558 9037 12089 813 -968 -2814 C ATOM 969 C4' U A 6 45.925 35.689 60.405 1.00 76.33 C ANISOU 969 C4' U A 6 7440 8933 12629 620 -823 -2966 C ATOM 970 O4' U A 6 45.673 35.543 58.986 1.00 74.55 O ANISOU 970 O4' U A 6 7311 8539 12474 413 -541 -2704 O ATOM 971 C3' U A 6 45.203 36.980 60.747 1.00 76.73 C ANISOU 971 C3' U A 6 7446 8956 12749 569 -814 -3044 C ATOM 972 O3' U A 6 45.664 37.510 61.975 1.00 79.69 O ANISOU 972 O3' U A 6 7638 9447 13191 738 -1063 -3390 O ATOM 973 C2' U A 6 45.545 37.844 59.540 1.00 76.62 C ANISOU 973 C2' U A 6 7298 8683 13129 344 -544 -3032 C ATOM 974 O2' U A 6 46.864 38.360 59.568 1.00 78.89 O ANISOU 974 O2' U A 6 7275 8853 13845 335 -565 -3357 O ATOM 975 C1' U A 6 45.378 36.814 58.425 1.00 74.55 C ANISOU 975 C1' U A 6 7228 8377 12719 256 -367 -2715 C ATOM 976 N1 U A 6 44.000 36.817 57.815 1.00 72.03 N ANISOU 976 N1 U A 6 7158 8061 12149 161 -211 -2390 N ATOM 977 C2 U A 6 43.723 37.689 56.773 1.00 71.57 C ANISOU 977 C2 U A 6 7085 7827 12280 1 40 -2278 C ATOM 978 O2 U A 6 44.536 38.469 56.307 1.00 72.71 O ANISOU 978 O2 U A 6 7033 7790 12803 -75 174 -2412 O ATOM 979 N3 U A 6 42.437 37.617 56.286 1.00 69.91 N ANISOU 979 N3 U A 6 7099 7656 11805 -52 144 -2001 N ATOM 980 C4 U A 6 41.420 36.781 56.725 1.00 68.55 C ANISOU 980 C4 U A 6 7143 7656 11245 15 37 -1841 C ATOM 981 O4 U A 6 40.316 36.828 56.192 1.00 67.24 O ANISOU 981 O4 U A 6 7140 7505 10902 -46 145 -1624 O ATOM 982 C5 U A 6 41.778 35.901 57.810 1.00 69.03 C ANISOU 982 C5 U A 6 7212 7866 11148 174 -190 -1952 C ATOM 983 C6 U A 6 43.025 35.955 58.299 1.00 70.76 C ANISOU 983 C6 U A 6 7230 8073 11583 250 -309 -2211 C ATOM 984 P A A 7 44.596 38.141 62.988 1.00 80.06 P ANISOU 984 P A A 7 7776 9631 13010 834 -1187 -3418 P ATOM 985 OP1 A A 7 45.277 38.357 64.284 1.00 82.84 O ANISOU 985 OP1 A A 7 7947 10150 13376 1067 -1486 -3796 O ATOM 986 OP2 A A 7 43.358 37.328 62.943 1.00 77.58 O ANISOU 986 OP2 A A 7 7793 9412 12271 854 -1129 -3050 O ATOM 987 O5' A A 7 44.298 39.563 62.317 1.00 80.25 O ANISOU 987 O5' A A 7 7677 9436 13377 612 -976 -3449 O ATOM 988 C5' A A 7 45.365 40.491 62.118 1.00 82.82 C ANISOU 988 C5' A A 7 7676 9590 14199 533 -932 -3768 C ATOM 989 C4' A A 7 44.984 41.578 61.131 1.00 82.59 C ANISOU 989 C4' A A 7 7605 9309 14463 306 -626 -3655 C ATOM 990 O4' A A 7 44.684 41.022 59.827 1.00 80.63 O ANISOU 990 O4' A A 7 7544 8953 14137 170 -372 -3289 O ATOM 991 C3' A A 7 43.720 42.347 61.474 1.00 81.84 C ANISOU 991 C3' A A 7 7633 9248 14212 285 -599 -3551 C ATOM 992 O3' A A 7 43.981 43.278 62.515 1.00 84.42 O ANISOU 992 O3' A A 7 7738 9609 14726 366 -766 -3926 O ATOM 993 C2' A A 7 43.407 43.000 60.130 1.00 80.85 C ANISOU 993 C2' A A 7 7535 8873 14308 74 -243 -3317 C ATOM 994 O2' A A 7 44.196 44.142 59.852 1.00 82.84 O ANISOU 994 O2' A A 7 7498 8889 15088 -23 -88 -3558 O ATOM 995 C1' A A 7 43.757 41.870 59.165 1.00 79.62 C ANISOU 995 C1' A A 7 7507 8699 14046 34 -139 -3084 C ATOM 996 N9 A A 7 42.591 41.093 58.739 1.00 76.98 N ANISOU 996 N9 A A 7 7492 8473 13283 25 -91 -2710 N ATOM 997 C8 A A 7 42.188 39.875 59.216 1.00 75.91 C ANISOU 997 C8 A A 7 7550 8542 12749 139 -261 -2591 C ATOM 998 N7 A A 7 41.102 39.408 58.647 1.00 73.76 N ANISOU 998 N7 A A 7 7522 8309 12192 89 -156 -2274 N ATOM 999 C5 A A 7 40.764 40.389 57.730 1.00 73.51 C ANISOU 999 C5 A A 7 7467 8110 12351 -49 82 -2170 C ATOM 1000 C6 A A 7 39.704 40.502 56.802 1.00 71.87 C ANISOU 1000 C6 A A 7 7441 7872 11993 -136 271 -1875 C ATOM 1001 N6 A A 7 38.758 39.569 56.657 1.00 69.92 N ANISOU 1001 N6 A A 7 7421 7760 11383 -116 239 -1652 N ATOM 1002 N1 A A 7 39.650 41.616 56.032 1.00 72.44 N ANISOU 1002 N1 A A 7 7443 7769 12312 -231 501 -1827 N ATOM 1003 C2 A A 7 40.598 42.553 56.185 1.00 74.37 C ANISOU 1003 C2 A A 7 7441 7849 12967 -259 561 -2064 C ATOM 1004 N3 A A 7 41.643 42.554 57.019 1.00 75.93 N ANISOU 1004 N3 A A 7 7428 8049 13373 -203 395 -2382 N ATOM 1005 C4 A A 7 41.670 41.438 57.773 1.00 75.42 C ANISOU 1005 C4 A A 7 7449 8188 13017 -90 143 -2419 C ATOM 1006 P U A 8 42.918 43.491 63.695 1.00 84.39 P ANISOU 1006 P U A 8 7871 9818 14374 508 -966 -3944 P ATOM 1007 OP1 U A 8 43.633 44.130 64.823 1.00 87.24 O ANISOU 1007 OP1 U A 8 7956 10258 14932 645 -1206 -4420 O ATOM 1008 OP2 U A 8 42.178 42.225 63.916 1.00 82.22 O ANISOU 1008 OP2 U A 8 7912 9745 13579 624 -1057 -3644 O ATOM 1009 O5' U A 8 41.903 44.549 63.056 1.00 83.31 O ANISOU 1009 O5' U A 8 7799 9506 14345 325 -702 -3745 O ATOM 1010 C5' U A 8 42.398 45.764 62.492 1.00 85.02 C ANISOU 1010 C5' U A 8 7768 9458 15076 171 -487 -3902 C ATOM 1011 C4' U A 8 41.426 46.360 61.488 1.00 83.45 C ANISOU 1011 C4' U A 8 7720 9094 14892 10 -175 -3560 C ATOM 1012 O4' U A 8 41.330 45.538 60.297 1.00 81.54 O ANISOU 1012 O4' U A 8 7664 8804 14511 -64 4 -3210 O ATOM 1013 C3' U A 8 39.985 46.462 61.961 1.00 81.74 C ANISOU 1013 C3' U A 8 7737 9021 14298 51 -232 -3363 C ATOM 1014 O3' U A 8 39.832 47.550 62.868 1.00 83.14 O ANISOU 1014 O3' U A 8 7755 9192 14643 84 -315 -3641 O ATOM 1015 C2' U A 8 39.253 46.643 60.630 1.00 80.05 C ANISOU 1015 C2' U A 8 7690 8658 14067 -94 82 -2975 C ATOM 1016 O2' U A 8 39.292 47.964 60.122 1.00 81.35 O ANISOU 1016 O2' U A 8 7702 8578 14626 -207 338 -3012 O ATOM 1017 C1' U A 8 40.039 45.685 59.729 1.00 79.66 C ANISOU 1017 C1' U A 8 7666 8566 14033 -125 160 -2860 C ATOM 1018 N1 U A 8 39.362 44.344 59.587 1.00 77.59 N ANISOU 1018 N1 U A 8 7688 8497 13294 -70 67 -2580 N ATOM 1019 C2 U A 8 38.401 44.167 58.598 1.00 75.77 C ANISOU 1019 C2 U A 8 7672 8245 12869 -146 255 -2226 C ATOM 1020 O2 U A 8 38.060 45.034 57.809 1.00 75.92 O ANISOU 1020 O2 U A 8 7684 8110 13049 -236 492 -2100 O ATOM 1021 N3 U A 8 37.839 42.912 58.558 1.00 73.94 N ANISOU 1021 N3 U A 8 7664 8183 12247 -96 160 -2027 N ATOM 1022 C4 U A 8 38.122 41.837 59.386 1.00 73.87 C ANISOU 1022 C4 U A 8 7701 8344 12022 24 -69 -2110 C ATOM 1023 O4 U A 8 37.532 40.774 59.222 1.00 72.31 O ANISOU 1023 O4 U A 8 7703 8256 11513 52 -94 -1904 O ATOM 1024 C5 U A 8 39.128 42.092 60.390 1.00 75.94 C ANISOU 1024 C5 U A 8 7752 8633 12466 122 -257 -2456 C ATOM 1025 C6 U A 8 39.693 43.307 60.450 1.00 77.64 C ANISOU 1025 C6 U A 8 7731 8700 13067 68 -195 -2688 C ATOM 1026 P U A 9 38.536 47.668 63.800 1.00 81.98 P ANISOU 1026 P U A 9 7797 9234 14117 180 -462 -3563 P ATOM 1027 OP1 U A 9 38.897 48.513 64.962 1.00 84.38 O ANISOU 1027 OP1 U A 9 7870 9580 14608 270 -644 -3987 O ATOM 1028 OP2 U A 9 37.957 46.320 64.020 1.00 79.87 O ANISOU 1028 OP2 U A 9 7812 9189 13342 291 -602 -3316 O ATOM 1029 O5' U A 9 37.558 48.498 62.844 1.00 80.56 O ANISOU 1029 O5' U A 9 7716 8870 14021 17 -150 -3264 O ATOM 1030 C5' U A 9 36.182 48.646 63.158 1.00 78.61 C ANISOU 1030 C5' U A 9 7677 8723 13465 38 -161 -3061 C ATOM 1031 C4' U A 9 35.329 48.608 61.904 1.00 76.13 C ANISOU 1031 C4' U A 9 7556 8315 13054 -77 100 -2651 C ATOM 1032 O4' U A 9 35.865 47.665 60.942 1.00 75.41 O ANISOU 1032 O4' U A 9 7529 8201 12920 -113 178 -2486 O ATOM 1033 C3' U A 9 33.911 48.122 62.140 1.00 73.62 C ANISOU 1033 C3' U A 9 7511 8165 12294 -32 37 -2387 C ATOM 1034 O3' U A 9 33.093 49.180 62.618 1.00 72.99 O ANISOU 1034 O3' U A 9 7416 8055 12259 -42 71 -2419 O ATOM 1035 C2' U A 9 33.503 47.627 60.756 1.00 72.13 C ANISOU 1035 C2' U A 9 7482 7920 12001 -120 243 -2035 C ATOM 1036 O2' U A 9 33.097 48.658 59.874 1.00 72.34 O ANISOU 1036 O2' U A 9 7487 7771 12225 -214 507 -1890 O ATOM 1037 C1' U A 9 34.807 46.995 60.270 1.00 72.99 C ANISOU 1037 C1' U A 9 7487 7974 12269 -132 251 -2124 C ATOM 1038 N1 U A 9 34.912 45.501 60.497 1.00 71.93 N ANISOU 1038 N1 U A 9 7495 8022 11813 -51 75 -2060 N ATOM 1039 C2 U A 9 34.086 44.623 59.798 1.00 70.10 C ANISOU 1039 C2 U A 9 7489 7864 11281 -72 136 -1753 C ATOM 1040 O2 U A 9 33.239 44.964 58.986 1.00 69.31 O ANISOU 1040 O2 U A 9 7488 7715 11131 -141 304 -1530 O ATOM 1041 N3 U A 9 34.282 43.292 60.088 1.00 69.33 N ANISOU 1041 N3 U A 9 7491 7904 10945 3 -6 -1727 N ATOM 1042 C4 U A 9 35.196 42.753 60.978 1.00 70.30 C ANISOU 1042 C4 U A 9 7531 8111 11069 116 -203 -1948 C ATOM 1043 O4 U A 9 35.249 41.537 61.126 1.00 69.63 O ANISOU 1043 O4 U A 9 7562 8138 10755 188 -291 -1870 O ATOM 1044 C5 U A 9 36.021 43.718 61.664 1.00 72.32 C ANISOU 1044 C5 U A 9 7550 8310 11615 148 -283 -2271 C ATOM 1045 C6 U A 9 35.850 45.021 61.401 1.00 73.01 C ANISOU 1045 C6 U A 9 7521 8249 11969 55 -141 -2323 C ATOM 1046 P C A 10 32.522 49.139 64.113 1.00 72.60 P ANISOU 1046 P C A 10 7420 8203 11961 97 -182 -2576 P ATOM 1047 OP1 C A 10 32.374 50.539 64.565 1.00 74.18 O ANISOU 1047 OP1 C A 10 7457 8294 12433 65 -129 -2773 O ATOM 1048 OP2 C A 10 33.326 48.193 64.922 1.00 73.38 O ANISOU 1048 OP2 C A 10 7495 8467 11916 242 -433 -2771 O ATOM 1049 O5' C A 10 31.067 48.506 63.911 1.00 69.77 O ANISOU 1049 O5' C A 10 7354 7958 11197 104 -152 -2217 O ATOM 1050 C5' C A 10 30.914 47.108 63.708 1.00 67.21 C ANISOU 1050 C5' C A 10 7211 7760 10563 151 -217 -2032 C ATOM 1051 C4' C A 10 30.024 46.842 62.512 1.00 64.53 C ANISOU 1051 C4' C A 10 7029 7375 10112 47 -27 -1690 C ATOM 1052 O4' C A 10 30.755 46.098 61.505 1.00 63.82 O ANISOU 1052 O4' C A 10 6937 7240 10069 -3 48 -1602 O ATOM 1053 C3' C A 10 28.816 45.991 62.852 1.00 62.58 C ANISOU 1053 C3' C A 10 7008 7278 9491 104 -90 -1492 C ATOM 1054 O3' C A 10 27.733 46.833 63.208 1.00 61.97 O ANISOU 1054 O3' C A 10 6971 7195 9378 95 -52 -1444 O ATOM 1055 C2' C A 10 28.570 45.219 61.558 1.00 61.16 C ANISOU 1055 C2' C A 10 6933 7078 9226 23 40 -1242 C ATOM 1056 O2' C A 10 27.816 45.939 60.602 1.00 60.67 O ANISOU 1056 O2' C A 10 6895 6932 9223 -66 221 -1067 O ATOM 1057 C1' C A 10 29.995 44.990 61.058 1.00 61.97 C ANISOU 1057 C1' C A 10 6904 7105 9535 0 56 -1358 C ATOM 1058 N1 C A 10 30.617 43.701 61.546 1.00 61.77 N ANISOU 1058 N1 C A 10 6923 7191 9354 90 -96 -1417 N ATOM 1059 C2 C A 10 30.117 42.458 61.107 1.00 60.15 C ANISOU 1059 C2 C A 10 6885 7061 8908 91 -79 -1216 C ATOM 1060 O2 C A 10 29.167 42.410 60.315 1.00 58.71 O ANISOU 1060 O2 C A 10 6802 6868 8635 19 39 -1013 O ATOM 1061 N3 C A 10 30.696 41.318 61.565 1.00 60.36 N ANISOU 1061 N3 C A 10 6950 7171 8812 183 -193 -1260 N ATOM 1062 C4 C A 10 31.722 41.375 62.420 1.00 61.93 C ANISOU 1062 C4 C A 10 7033 7403 9092 288 -339 -1493 C ATOM 1063 N4 C A 10 32.251 40.221 62.837 1.00 62.13 N ANISOU 1063 N4 C A 10 7111 7518 8978 400 -442 -1511 N ATOM 1064 C5 C A 10 32.248 42.620 62.883 1.00 63.43 C ANISOU 1064 C5 C A 10 7040 7536 9524 291 -384 -1729 C ATOM 1065 C6 C A 10 31.673 43.740 62.424 1.00 63.26 C ANISOU 1065 C6 C A 10 6978 7409 9648 183 -250 -1682 C ATOM 1066 P G A 11 26.706 46.382 64.348 1.00 61.17 P ANISOU 1066 P G A 11 7026 7244 8969 209 -177 -1407 P ATOM 1067 OP1 G A 11 25.839 47.543 64.655 1.00 61.37 O ANISOU 1067 OP1 G A 11 7035 7226 9056 182 -122 -1409 O ATOM 1068 OP2 G A 11 27.463 45.732 65.443 1.00 61.93 O ANISOU 1068 OP2 G A 11 7113 7458 8959 363 -372 -1597 O ATOM 1069 O5' G A 11 25.840 45.262 63.600 1.00 59.02 O ANISOU 1069 O5' G A 11 6938 7020 8466 172 -102 -1123 O ATOM 1070 C5' G A 11 25.046 45.601 62.459 1.00 57.60 C ANISOU 1070 C5' G A 11 6793 6775 8316 58 60 -923 C ATOM 1071 C4' G A 11 24.230 44.415 61.981 1.00 56.01 C ANISOU 1071 C4' G A 11 6745 6647 7887 49 86 -724 C ATOM 1072 O4' G A 11 25.074 43.449 61.309 1.00 55.63 O ANISOU 1072 O4' G A 11 6694 6602 7841 31 90 -707 O ATOM 1073 C3' G A 11 23.576 43.601 63.085 1.00 55.77 C ANISOU 1073 C3' G A 11 6842 6719 7629 151 -5 -710 C ATOM 1074 O3' G A 11 22.408 44.258 63.547 1.00 55.94 O ANISOU 1074 O3' G A 11 6910 6748 7596 157 19 -660 O ATOM 1075 C2' G A 11 23.297 42.286 62.362 1.00 54.51 C ANISOU 1075 C2' G A 11 6775 6590 7344 121 42 -563 C ATOM 1076 O2' G A 11 22.154 42.334 61.528 1.00 53.24 O ANISOU 1076 O2' G A 11 6660 6424 7144 41 144 -409 O ATOM 1077 C1' G A 11 24.573 42.140 61.535 1.00 54.65 C ANISOU 1077 C1' G A 11 6699 6561 7504 75 55 -617 C ATOM 1078 N9 G A 11 25.605 41.338 62.198 1.00 55.09 N ANISOU 1078 N9 G A 11 6747 6655 7527 167 -50 -729 N ATOM 1079 C8 G A 11 26.654 41.802 62.959 1.00 56.16 C ANISOU 1079 C8 G A 11 6778 6792 7765 243 -160 -931 C ATOM 1080 N7 G A 11 27.419 40.859 63.431 1.00 56.52 N ANISOU 1080 N7 G A 11 6843 6896 7736 343 -250 -994 N ATOM 1081 C5 G A 11 26.844 39.688 62.958 1.00 55.53 C ANISOU 1081 C5 G A 11 6845 6790 7463 321 -177 -813 C ATOM 1082 C6 G A 11 27.235 38.338 63.145 1.00 55.48 C ANISOU 1082 C6 G A 11 6913 6826 7338 401 -200 -775 C ATOM 1083 O6 G A 11 28.200 37.906 63.787 1.00 56.61 O ANISOU 1083 O6 G A 11 7033 7015 7460 526 -303 -885 O ATOM 1084 N1 G A 11 26.386 37.444 62.496 1.00 54.45 N ANISOU 1084 N1 G A 11 6885 6683 7120 334 -86 -599 N ATOM 1085 C2 G A 11 25.287 37.813 61.755 1.00 53.74 C ANISOU 1085 C2 G A 11 6815 6564 7038 216 12 -490 C ATOM 1086 N2 G A 11 24.584 36.813 61.206 1.00 53.12 N ANISOU 1086 N2 G A 11 6812 6484 6888 170 101 -370 N ATOM 1087 N3 G A 11 24.905 39.075 61.569 1.00 53.81 N ANISOU 1087 N3 G A 11 6765 6547 7130 158 25 -510 N ATOM 1088 C4 G A 11 25.724 39.962 62.197 1.00 54.74 C ANISOU 1088 C4 G A 11 6790 6657 7351 209 -61 -666 C ATOM 1089 P C A 12 21.800 43.889 64.978 1.00 56.46 P ANISOU 1089 P C A 12 7086 6895 7471 292 -60 -686 P ATOM 1090 OP1 C A 12 20.996 45.042 65.443 1.00 56.80 O ANISOU 1090 OP1 C A 12 7113 6917 7550 286 -40 -706 O ATOM 1091 OP2 C A 12 22.877 43.345 65.839 1.00 57.13 O ANISOU 1091 OP2 C A 12 7163 7041 7501 426 -188 -834 O ATOM 1092 O5' C A 12 20.800 42.714 64.561 1.00 55.85 O ANISOU 1092 O5' C A 12 7138 6841 7240 267 21 -492 O ATOM 1093 C5' C A 12 20.227 41.869 65.536 1.00 56.34 C ANISOU 1093 C5' C A 12 7329 6952 7125 382 14 -444 C ATOM 1094 C4' C A 12 20.318 40.425 65.090 1.00 56.22 C ANISOU 1094 C4' C A 12 7378 6940 7042 378 64 -351 C ATOM 1095 O4' C A 12 21.561 40.176 64.380 1.00 56.45 O ANISOU 1095 O4' C A 12 7326 6960 7159 339 23 -414 O ATOM 1096 C3' C A 12 20.369 39.424 66.228 1.00 57.24 C ANISOU 1096 C3' C A 12 7630 7110 7008 550 53 -333 C ATOM 1097 O3' C A 12 19.074 39.226 66.775 1.00 57.33 O ANISOU 1097 O3' C A 12 7743 7106 6932 586 148 -227 O ATOM 1098 C2' C A 12 20.896 38.201 65.487 1.00 56.93 C ANISOU 1098 C2' C A 12 7596 7052 6981 513 96 -280 C ATOM 1099 O2' C A 12 19.910 37.582 64.682 1.00 56.05 O ANISOU 1099 O2' C A 12 7508 6893 6895 399 223 -160 O ATOM 1100 C1' C A 12 21.974 38.837 64.607 1.00 56.62 C ANISOU 1100 C1' C A 12 7419 7003 7088 416 26 -381 C ATOM 1101 N1 C A 12 23.358 38.797 65.214 1.00 57.65 N ANISOU 1101 N1 C A 12 7506 7176 7221 535 -97 -524 N ATOM 1102 C2 C A 12 24.072 37.582 65.271 1.00 58.17 C ANISOU 1102 C2 C A 12 7614 7260 7225 611 -104 -507 C ATOM 1103 O2 C A 12 23.574 36.542 64.820 1.00 57.74 O ANISOU 1103 O2 C A 12 7631 7174 7131 572 4 -377 O ATOM 1104 N3 C A 12 25.313 37.570 65.828 1.00 59.19 N ANISOU 1104 N3 C A 12 7692 7441 7355 734 -231 -651 N ATOM 1105 C4 C A 12 25.846 38.694 66.313 1.00 59.86 C ANISOU 1105 C4 C A 12 7673 7555 7514 774 -350 -829 C ATOM 1106 N4 C A 12 27.069 38.617 66.846 1.00 60.95 N ANISOU 1106 N4 C A 12 7740 7753 7664 903 -487 -999 N ATOM 1107 C5 C A 12 25.145 39.940 66.270 1.00 59.60 C ANISOU 1107 C5 C A 12 7592 7490 7563 686 -331 -855 C ATOM 1108 C6 C A 12 23.922 39.941 65.720 1.00 58.48 C ANISOU 1108 C6 C A 12 7516 7300 7401 573 -203 -688 C ATOM 1109 P U A 13 18.879 38.962 68.344 1.00 58.67 P ANISOU 1109 P U A 13 8047 7320 6923 811 142 -222 P ATOM 1110 OP1 U A 13 17.548 39.499 68.702 1.00 58.66 O ANISOU 1110 OP1 U A 13 8092 7288 6908 791 225 -155 O ATOM 1111 OP2 U A 13 20.079 39.438 69.071 1.00 59.69 O ANISOU 1111 OP2 U A 13 8138 7534 7004 952 -21 -389 O ATOM 1112 O5' U A 13 18.854 37.362 68.447 1.00 59.02 O ANISOU 1112 O5' U A 13 8200 7335 6888 891 258 -99 O ATOM 1113 C5' U A 13 17.991 36.590 67.611 1.00 57.86 C ANISOU 1113 C5' U A 13 8055 7100 6825 754 412 17 C ATOM 1114 C4' U A 13 16.996 35.799 68.438 1.00 58.49 C ANISOU 1114 C4' U A 13 8270 7120 6830 866 584 145 C ATOM 1115 O4' U A 13 16.246 36.693 69.297 1.00 59.04 O ANISOU 1115 O4' U A 13 8389 7208 6834 936 582 145 O ATOM 1116 C3' U A 13 15.920 35.085 67.637 1.00 57.78 C ANISOU 1116 C3' U A 13 8153 6925 6872 715 754 229 C ATOM 1117 O3' U A 13 16.399 33.839 67.143 1.00 57.51 O ANISOU 1117 O3' U A 13 8118 6846 6885 700 828 260 O ATOM 1118 C2' U A 13 14.830 34.897 68.687 1.00 58.74 C ANISOU 1118 C2' U A 13 8391 6984 6940 832 912 328 C ATOM 1119 O2' U A 13 15.066 33.802 69.551 1.00 59.75 O ANISOU 1119 O2' U A 13 8657 7070 6976 1028 1044 425 O ATOM 1120 C1' U A 13 14.925 36.202 69.476 1.00 59.21 C ANISOU 1120 C1' U A 13 8473 7132 6890 920 777 265 C ATOM 1121 N1 U A 13 13.917 37.265 69.087 1.00 58.69 N ANISOU 1121 N1 U A 13 8329 7053 6918 774 768 243 N ATOM 1122 C2 U A 13 12.549 37.045 69.239 1.00 59.04 C ANISOU 1122 C2 U A 13 8402 7006 7024 741 937 328 C ATOM 1123 O2 U A 13 12.054 36.018 69.673 1.00 59.93 O ANISOU 1123 O2 U A 13 8598 7028 7144 815 1121 424 O ATOM 1124 N3 U A 13 11.743 38.091 68.855 1.00 58.54 N ANISOU 1124 N3 U A 13 8257 6948 7038 620 902 297 N ATOM 1125 C4 U A 13 12.151 39.314 68.350 1.00 58.05 C ANISOU 1125 C4 U A 13 8099 6959 6998 537 741 208 C ATOM 1126 O4 U A 13 11.309 40.156 68.049 1.00 58.14 O ANISOU 1126 O4 U A 13 8049 6961 7078 449 744 206 O ATOM 1127 C5 U A 13 13.580 39.477 68.223 1.00 57.76 C ANISOU 1127 C5 U A 13 8035 6994 6917 571 595 124 C ATOM 1128 C6 U A 13 14.387 38.471 68.588 1.00 57.99 C ANISOU 1128 C6 U A 13 8132 7031 6867 683 603 136 C HETATM 1129 N1 OMU A 14 11.768 36.627 65.456 1.00 54.12 N ANISOU 1129 N1 OMU A 14 7414 6359 6789 228 913 229 N HETATM 1130 C2 OMU A 14 10.828 37.648 65.530 1.00 53.84 C ANISOU 1130 C2 OMU A 14 7345 6333 6776 192 901 228 C HETATM 1131 N3 OMU A 14 11.317 38.913 65.278 1.00 53.15 N ANISOU 1131 N3 OMU A 14 7217 6325 6653 170 758 188 N HETATM 1132 C4 OMU A 14 12.625 39.253 64.964 1.00 52.86 C ANISOU 1132 C4 OMU A 14 7157 6346 6579 176 635 138 C HETATM 1133 C5 OMU A 14 13.544 38.140 64.905 1.00 53.09 C ANISOU 1133 C5 OMU A 14 7219 6369 6584 212 643 132 C HETATM 1134 C6 OMU A 14 13.093 36.899 65.146 1.00 53.53 C ANISOU 1134 C6 OMU A 14 7324 6356 6655 238 775 182 C HETATM 1135 O2 OMU A 14 9.651 37.465 65.796 1.00 54.11 O ANISOU 1135 O2 OMU A 14 7378 6300 6878 179 1021 260 O HETATM 1136 O4 OMU A 14 12.919 40.429 64.767 1.00 52.46 O ANISOU 1136 O4 OMU A 14 7058 6335 6539 153 548 101 O HETATM 1137 C1' OMU A 14 11.325 35.208 65.709 1.00 55.05 C ANISOU 1137 C1' OMU A 14 7573 6368 6975 256 1099 277 C HETATM 1138 C2' OMU A 14 10.805 34.508 64.451 1.00 55.02 C ANISOU 1138 C2' OMU A 14 7437 6337 7131 103 1146 215 C HETATM 1139 O2' OMU A 14 9.639 33.756 64.745 1.00 56.21 O ANISOU 1139 O2' OMU A 14 7574 6362 7418 91 1343 234 O HETATM 1140 CM2 OMU A 14 8.352 34.297 64.479 1.00 56.42 C ANISOU 1140 CM2 OMU A 14 7510 6378 7546 12 1365 194 C HETATM 1141 C3' OMU A 14 11.995 33.635 64.069 1.00 54.97 C ANISOU 1141 C3' OMU A 14 7441 6340 7104 114 1123 201 C HETATM 1142 C4' OMU A 14 12.479 33.201 65.444 1.00 55.87 C ANISOU 1142 C4' OMU A 14 7713 6402 7112 298 1207 297 C HETATM 1143 O3' OMU A 14 11.605 32.514 63.294 1.00 55.64 O ANISOU 1143 O3' OMU A 14 7441 6358 7339 23 1232 152 O HETATM 1144 O4' OMU A 14 12.388 34.422 66.219 1.00 55.61 O ANISOU 1144 O4' OMU A 14 7736 6431 6963 374 1115 311 O HETATM 1145 C5' OMU A 14 13.890 32.646 65.506 1.00 56.03 C ANISOU 1145 C5' OMU A 14 7783 6456 7048 377 1147 301 C HETATM 1146 O5' OMU A 14 14.838 33.652 65.168 1.00 55.75 O ANISOU 1146 O5' OMU A 14 7707 6540 6932 358 937 233 O HETATM 1147 P OMU A 14 16.379 33.514 65.574 1.00 56.23 P ANISOU 1147 P OMU A 14 7820 6661 6882 481 827 215 P HETATM 1148 OP1 OMU A 14 16.794 32.105 65.409 1.00 56.84 O ANISOU 1148 OP1 OMU A 14 7926 6675 6996 509 939 254 O HETATM 1149 OP2 OMU A 14 17.121 34.587 64.877 1.00 55.26 O ANISOU 1149 OP2 OMU A 14 7601 6627 6768 396 647 120 O TER 1150 OMU A 14 HETATM 1151 O HOH X 1 8.190 8.752 58.158 1.00 33.31 O ANISOU 1151 O HOH X 1 4886 3083 4686 -1257 -1202 -27 O HETATM 1152 O HOH X 2 13.109 28.407 75.299 1.00 39.51 O ANISOU 1152 O HOH X 2 6129 6159 2723 57 319 -423 O HETATM 1153 O HOH X 4 4.018 9.950 55.359 1.00 37.06 O ANISOU 1153 O HOH X 4 4464 4183 5432 -1712 -1528 -470 O HETATM 1154 O HOH X 5 -1.168 28.831 62.314 1.00 43.45 O ANISOU 1154 O HOH X 5 2559 7426 6522 898 380 -657 O HETATM 1155 O HOH X 6 22.766 36.549 68.513 1.00 35.53 O ANISOU 1155 O HOH X 6 4644 4447 4407 -153 -827 -1010 O HETATM 1156 O HOH A 15 26.901 25.075 42.890 1.00 44.85 O ANISOU 1156 O HOH A 15 5434 5900 5705 -441 871 -894 O CONECT 42 51 CONECT 51 42 52 CONECT 52 51 53 55 CONECT 53 52 54 59 CONECT 54 53 CONECT 55 52 56 CONECT 56 55 57 CONECT 57 56 58 CONECT 58 57 CONECT 59 53 CONECT 756 759 CONECT 759 756 760 CONECT 760 759 761 763 CONECT 761 760 762 767 CONECT 762 761 CONECT 763 760 764 CONECT 764 763 765 CONECT 765 764 766 CONECT 766 765 CONECT 767 761 CONECT 1117 1147 CONECT 1129 1130 1134 1137 CONECT 1130 1129 1131 1135 CONECT 1131 1130 1132 CONECT 1132 1131 1133 1136 CONECT 1133 1132 1134 CONECT 1134 1129 1133 CONECT 1135 1130 CONECT 1136 1132 CONECT 1137 1129 1138 1144 CONECT 1138 1137 1139 1141 CONECT 1139 1138 1140 CONECT 1140 1139 CONECT 1141 1138 1142 1143 CONECT 1142 1141 1144 1145 CONECT 1143 1141 CONECT 1144 1137 1142 CONECT 1145 1142 1146 CONECT 1146 1145 1147 CONECT 1147 1117 1146 1148 1149 CONECT 1148 1147 CONECT 1149 1147 MASTER 365 0 3 4 8 0 0 6 1154 2 42 12 END
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Related entries of code: 3o6e
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
3o3i
RCSB PDB
PDBbind
14aa, >3O3I_2|Chain... *
4ngb
RCSB PDB
PDBbind
12aa, >4NGB_2|Chain... at 100%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
3o6e
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
human Hiwi1 PAZ domain (residues 277-399)
Ligand Name
14-mer RNA (12-bp and 2-nt overhang) containing 2'-OCH3 at its 3'-end
EC.Number
E.C.-.-.-.-
Resolution
2.9(Å)
Affinity (Kd/Ki/IC50)
Kd=6.5uM
Release Year
2011
Protein/NA Sequence
Check fasta file
Primary Reference
(2011) Proc.Natl.Acad.Sci.USA Vol. 108: pp. 903-910
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q96J94
Entrez Gene ID
NCBI Entrez Gene ID:
9271
ASD
Information of known allosteric effects of PDB entries
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times since Nov 2007.
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