Browse entries in the PDBbind-CN Database

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Related entries of code: 4gts
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3c72RCSB PDB    PDBbind331aa, >3C72_2|Chain... at 95%
3dstRCSB PDB    PDBbind331aa, >3DST_2|Chain... at 95%
3dsuRCSB PDB    PDBbind331aa, >3DSU_2|Chain... at 95%
3hxbRCSB PDB    PDBbind331aa, >3HXB_2|Chain... at 95%
3hxcRCSB PDB    PDBbind331aa, >3HXC_2|Chain... at 95%
3hxdRCSB PDB    PDBbind331aa, >3HXD_2|Chain... at 95%
3hxeRCSB PDB    PDBbind331aa, >3HXE_2|Chain... at 95%
3hxfRCSB PDB    PDBbind331aa, >3HXF_2|Chain... at 95%
3pz1RCSB PDB    PDBbind330aa, >3PZ1_2|Chain... at 95%
3pz2RCSB PDB    PDBbind330aa, >3PZ2_2|Chain... at 95%
3pz3RCSB PDB    PDBbind330aa, >3PZ3_2|Chain... at 95%
4ehmRCSB PDB    PDBbind330aa, >4EHM_2|Chain... at 95%
4gttRCSB PDB    PDBbind330aa, >4GTT_2|Chain... at 95%
4gtvRCSB PDB    PDBbind330aa, >4GTV_2|Chain... at 95%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4gtpRCSB PDB    PDBbind7TP
Entry Information
PDB ID4gts
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameGeranylgeranyl transferase type-2 subunit alpha; Geranylgeranyl transferase type-2 subunit beta
Ligand Name7TP
EC.Number E.C.2.5.1.60
Resolution 2.45(Å)
Affinity (Kd/Ki/IC50)IC50=12.8nM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2012) J.Med.Chem. Vol. 55: pp. 8330-8340
Ligand Properties
Formula C33H32N4O6S
Molecular Weight 612.695
Exact Mass 612.204
No. of atoms 76
No. of bonds 81
Polar Surface Area 126.49
LOGP Value 4.24      (Computed with XLOGP3)
6.11      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 10
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 6
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q08602  Q08603  
Entrez Gene IDNCBI Entrez Gene ID: 58983  25533  
ASDInformation of known allosteric effects of PDB entries
 
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