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Related entries of code: 4h71
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1q4kRCSB PDB    PDBbind259aa, >1Q4K_1|Chains... *
1umwRCSB PDB    PDBbind237aa, >1UMW_1|Chains... at 100%
3bziRCSB PDB    PDBbind239aa, >3BZI_1|Chain... at 100%
3fvhRCSB PDB    PDBbind237aa, >3FVH_1|Chain... at 98%
3hikRCSB PDB    PDBbind237aa, >3HIK_1|Chain... at 100%
3rq7RCSB PDB    PDBbind237aa, >3RQ7_1|Chain... at 98%
4dfwRCSB PDB    PDBbind237aa, >4DFW_1|Chain... at 100%
4e67RCSB PDB    PDBbind232aa, >4E67_1|Chain... at 96%
4e9dRCSB PDB    PDBbind232aa, >4E9D_1|Chain... at 96%
4hcoRCSB PDB    PDBbind240aa, >4HCO_1|Chains... at 98%
4lklRCSB PDB    PDBbind222aa, >4LKL_1|Chain... at 100%
4lkmRCSB PDB    PDBbind231aa, >4LKM_1|Chains... at 100%
4o6wRCSB PDB    PDBbind237aa, >4O6W_1|Chain... at 98%
4o9wRCSB PDB    PDBbind222aa, >4O9W_1|Chain... at 100%
4rcpRCSB PDB    PDBbind228aa, >4RCP_1|Chain... at 100%
4whhRCSB PDB    PDBbind237aa, >4WHH_1|Chain... at 98%
4whlRCSB PDB    PDBbind237aa, >4WHL_1|Chain... at 98%
4x9rRCSB PDB    PDBbind237aa, >4X9R_1|Chain... at 98%
4x9vRCSB PDB    PDBbind237aa, >4X9V_1|Chain... at 98%
4x9wRCSB PDB    PDBbind237aa, >4X9W_1|Chain... at 98%
5dmsRCSB PDB    PDBbind237aa, >5DMS_1|Chains... at 95%
6ax4RCSB PDB    PDBbind237aa, >6AX4_1|Chain... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4h71
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameSerine/threonine-protein kinase PLK1
Ligand NamePXE
EC.Number E.C.2.7.11.21
Resolution 1.93(Å)
Affinity (Kd/Ki/IC50)IC50=35.57uM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2013) Acs Chem.Biol. Vol. 8: pp. 303-308
Ligand Properties
Formula C10H13NO2
Molecular Weight 179.216
Exact Mass 179.095
No. of atoms 26
No. of bonds 26
Polar Surface Area 49.66
LOGP Value 1.80      (Computed with XLOGP3)
1.93      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 3
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P53350  
Entrez Gene IDNCBI Entrez Gene ID: 5347  
ASDInformation of known allosteric effects of PDB entries
 
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