Browse entries in the PDBbind-CN Database

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Related entries of code: 4hvs
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1t46RCSB PDB    PDBbind313aa, >1T46_1|Chain... at 100%
3g0eRCSB PDB    PDBbind336aa, >3G0E_1|Chain... *
3g0fRCSB PDB    PDBbind336aa, >3G0F_1|Chains... at 99%
4u0iRCSB PDB    PDBbind315aa, >4U0I_1|Chain... at 100%
6gqmRCSB PDB    PDBbind328aa, >6GQM_1|Chains... at 90%
6mobRCSB PDB    PDBbind312aa, >6MOB_1|Chain... at 100%
6klaRCSB PDB    PDBbind331aa, >6KLA_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4hvs
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMast/stem cell growth factor receptor Kit
Ligand Name647
EC.Number E.C.2.7.10.1
Resolution 1.9(Å)
Affinity (Kd/Ki/IC50)IC50=0.016uM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) Proc.Natl.Acad.Sci.USA Vol. 110: pp. 5689-5694
Ligand Properties
Formula C21H17F3N4
Molecular Weight 382.382
Exact Mass 382.141
No. of atoms 45
No. of bonds 48
Polar Surface Area 53.6
LOGP Value 4.86      (Computed with XLOGP3)
5.25      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P10721  
Entrez Gene IDNCBI Entrez Gene ID: 3815  
ASDInformation of known allosteric effects of PDB entries
 
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