Browse entries in the PDBbind-CN Database

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Related entries of code: 3g0f
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1t46RCSB PDB    PDBbind313aa, >1T46_1|Chain... at 100%
3g0eRCSB PDB    PDBbind336aa, >3G0E_1|Chain... *
4hvsRCSB PDB    PDBbind335aa, >4HVS_1|Chain... at 92%
4u0iRCSB PDB    PDBbind315aa, >4U0I_1|Chain... at 100%
6gqmRCSB PDB    PDBbind328aa, >6GQM_1|Chains... at 90%
6mobRCSB PDB    PDBbind312aa, >6MOB_1|Chain... at 100%
6klaRCSB PDB    PDBbind331aa, >6KLA_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3g0eRCSB PDB    PDBbindB49
3miyRCSB PDB    PDBbindB49
3ti1RCSB PDB    PDBbindB49
4agdRCSB PDB    PDBbindB49
4qmzRCSB PDB    PDBbindB49
6ng0RCSB PDB    PDBbindB49
6nfzRCSB PDB    PDBbindB49
6nfyRCSB PDB    PDBbindB49
Entry Information
PDB ID3g0f
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMast/stem cell growth factor receptor, D816H mutant KIT kinase domain
Ligand NameB49
EC.Number E.C.2.7.10.1
Resolution 2.6(Å)
Affinity (Kd/Ki/IC50)Kd=22nM
Release Year2009
Protein/NA SequenceCheck fasta file
Primary Reference (2009) Proc.Natl.Acad.Sci.USA Vol. 106: pp. 1542-1547
Ligand Properties
Formula C16H14FN3O2
Molecular Weight 299.300
Exact Mass 299.107
No. of atoms 36
No. of bonds 38
Polar Surface Area 87.98
LOGP Value 1.46      (Computed with XLOGP3)
3.20      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P10721  
Entrez Gene IDNCBI Entrez Gene ID: 3815  
ASDInformation of known allosteric effects of PDB entries
 
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