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Related entries of code: 4agd
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2oh4RCSB PDB    PDBbind316aa, >2OH4_1|Chain... at 99%
2p2hRCSB PDB    PDBbind314aa, >2P2H_1|Chain... at 97%
2p2iRCSB PDB    PDBbind314aa, >2P2I_1|Chains... at 97%
2qu5RCSB PDB    PDBbind314aa, >2QU5_1|Chain... at 97%
2qu6RCSB PDB    PDBbind314aa, >2QU6_1|Chains... at 97%
2rl5RCSB PDB    PDBbind314aa, >2RL5_1|Chain... at 97%
3b8qRCSB PDB    PDBbind314aa, >3B8Q_1|Chains... at 97%
3b8rRCSB PDB    PDBbind314aa, >3B8R_1|Chains... at 97%
3be2RCSB PDB    PDBbind314aa, >3BE2_1|Chain... at 97%
3c7qRCSB PDB    PDBbind316aa, >3C7Q_1|Chain... at 99%
3cjfRCSB PDB    PDBbind309aa, >3CJF_1|Chain... at 99%
3cp9RCSB PDB    PDBbind314aa, >3CP9_1|Chains... at 97%
3cpbRCSB PDB    PDBbind314aa, >3CPB_1|Chains... at 97%
3cpcRCSB PDB    PDBbind314aa, >3CPC_1|Chains... at 97%
3ewhRCSB PDB    PDBbind314aa, >3EWH_1|Chain... at 97%
3u6jRCSB PDB    PDBbind314aa, >3U6J_1|Chain... at 97%
3vntRCSB PDB    PDBbind318aa, >3VNT_1|Chain... at 99%
3vo3RCSB PDB    PDBbind318aa, >3VO3_1|Chain... at 99%
4ag8RCSB PDB    PDBbind316aa, >4AG8_1|Chain... at 100%
4agcRCSB PDB    PDBbind353aa, >4AGC_1|Chain... *
4asdRCSB PDB    PDBbind353aa, >4ASD_1|Chain... at 100%
4aseRCSB PDB    PDBbind353aa, >4ASE_1|Chain... at 100%
5ew3RCSB PDB    PDBbind316aa, >5EW3_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3g0eRCSB PDB    PDBbindB49
3g0fRCSB PDB    PDBbindB49
3miyRCSB PDB    PDBbindB49
3ti1RCSB PDB    PDBbindB49
4qmzRCSB PDB    PDBbindB49
6ng0RCSB PDB    PDBbindB49
6nfzRCSB PDB    PDBbindB49
6nfyRCSB PDB    PDBbindB49
Entry Information
PDB ID4agd
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameVascular endothelial growth factor receptor 2, VEGFR2 juxtamembrane and kinase domain
Ligand NameB49
EC.Number E.C.2.7.10.1
Resolution 2.81(Å)
Affinity (Kd/Ki/IC50)Ki=3.9nM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2012) Proc.Natl.Acad.Sci.USA Vol. 109: pp. 18281-18289
Ligand Properties
Formula C22H28FN4O2
Molecular Weight 399.482
Exact Mass 399.220
No. of atoms 57
No. of bonds 59
Polar Surface Area 78.43
LOGP Value 2.63      (Computed with XLOGP3)
2.45      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P35968  
Entrez Gene IDNCBI Entrez Gene ID: 3791  
ASDInformation of known allosteric effects of PDB entries
 
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