Browse entries in the PDBbind-CN Database

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Related entries of code: 4kb8
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3uytRCSB PDB    PDBbind296aa, >3UYT_1|Chains... at 98%
3uzpRCSB PDB    PDBbind296aa, >3UZP_1|Chains... at 98%
4hgtRCSB PDB    PDBbind296aa, >4HGT_1|Chains... at 98%
4hnfRCSB PDB    PDBbind296aa, >4HNF_1|Chains... at 98%
4hniRCSB PDB    PDBbind296aa, >4HNI_1|Chains... at 95%
4kbaRCSB PDB    PDBbind331aa, >4KBA_1|Chains... at 100%
4kbcRCSB PDB    PDBbind317aa, >4KBC_1|Chains... at 99%
4kbkRCSB PDB    PDBbind331aa, >4KBK_1|Chains... at 100%
4tw9RCSB PDB    PDBbind295aa, >4TW9_1|Chains... at 98%
4twcRCSB PDB    PDBbind295aa, >4TWC_1|Chains... at 98%
5ih5RCSB PDB    PDBbind294aa, >5IH5_1|Chain... at 99%
5ih6RCSB PDB    PDBbind294aa, >5IH6_1|Chain... at 99%
5mqvRCSB PDB    PDBbind314aa, >5MQV_1|Chains... at 97%
5oktRCSB PDB    PDBbind314aa, >5OKT_1|Chains... at 97%
5w4wRCSB PDB    PDBbind331aa, >5W4W_1|Chains... at 100%
6gzmRCSB PDB    PDBbind295aa, >6GZM_1|Chains... at 98%
6hmrRCSB PDB    PDBbind314aa, >6HMR_1|Chains... at 97%
6hmpRCSB PDB    PDBbind314aa, >6HMP_1|Chains... at 97%
6f26RCSB PDB    PDBbind314aa, >6F26_1|Chains... at 97%
6f1wRCSB PDB    PDBbind314aa, >6F1W_2|Chain... at 97%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4kb8
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameCasein kinase I isoform delta
Ligand Name1QN
EC.Number E.C.2.7.11.1 2.7.11.26
Resolution 1.95(Å)
Affinity (Kd/Ki/IC50)IC50=12.9nM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) J.Med.Chem. Vol. 56: pp. 6819-6828
Ligand Properties
Formula C17H18FN4
Molecular Weight 297.350
Exact Mass 297.152
No. of atoms 40
No. of bonds 42
Polar Surface Area 47.32
LOGP Value 1.96      (Computed with XLOGP3)
1.98      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P48730  
Entrez Gene IDNCBI Entrez Gene ID: 1453  
ASDInformation of known allosteric effects of PDB entries
 
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