Browse entries in the PDBbind-CN Database

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Related entries of code: 4m3q
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3bprRCSB PDB    PDBbind313aa, >3BPR_1|Chains... at 98%
3tcpRCSB PDB    PDBbind313aa, >3TCP_1|Chains... at 98%
4mh7RCSB PDB    PDBbind313aa, >4MH7_1|Chains... at 98%
4mhaRCSB PDB    PDBbind313aa, >4MHA_1|Chains... at 98%
5k0xRCSB PDB    PDBbind313aa, >5K0X_1|Chains... at 98%
5tc0RCSB PDB    PDBbind314aa, >5TC0_1|Chains... at 98%
5td2RCSB PDB    PDBbind285aa, >5TD2_1|Chains... at 100%
5u6cRCSB PDB    PDBbind315aa, >5U6C_1|Chains... *
6mepRCSB PDB    PDBbind313aa, >6MEP_1|Chains... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4m3q
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameTyrosine-protein kinase Mer
Ligand Name24K
EC.Number E.C.2.7.10.1
Resolution 2.72(Å)
Affinity (Kd/Ki/IC50)IC50=17nM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) J.Med.Chem. Vol. 56: pp. 9683-9692
Ligand Properties
Formula C19H27N5O
Molecular Weight 341.451
Exact Mass 341.222
No. of atoms 52
No. of bonds 54
Polar Surface Area 82.96
LOGP Value 3.33      (Computed with XLOGP3)
3.61      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q12866  
Entrez Gene IDNCBI Entrez Gene ID: 10461  
ASDInformation of known allosteric effects of PDB entries
 
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