Browse entries in the PDBbind-CN Database

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Related entries of code: 4mh7
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3bprRCSB PDB    PDBbind313aa, >3BPR_1|Chains... at 98%
3tcpRCSB PDB    PDBbind313aa, >3TCP_1|Chains... at 98%
4m3qRCSB PDB    PDBbind313aa, >4M3Q_1|Chains... at 98%
4mhaRCSB PDB    PDBbind313aa, >4MHA_1|Chains... at 98%
5k0xRCSB PDB    PDBbind313aa, >5K0X_1|Chains... at 98%
5tc0RCSB PDB    PDBbind314aa, >5TC0_1|Chains... at 98%
5td2RCSB PDB    PDBbind285aa, >5TD2_1|Chains... at 100%
5u6cRCSB PDB    PDBbind315aa, >5U6C_1|Chains... *
6mepRCSB PDB    PDBbind313aa, >6MEP_1|Chains... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4mh7
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namecatalytic domain of the proto-oncogene tyrosine-protein kinase MER
Ligand NameMH7
EC.Number E.C.2.7.10.1
Resolution 2.51(Å)
Affinity (Kd/Ki/IC50)IC50=5.9uM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2013) J.Med.Chem. Vol. 56: pp. 9693-9700
Ligand Properties
Formula C20H35N5O2
Molecular Weight 377.524
Exact Mass 377.279
No. of atoms 62
No. of bonds 63
Polar Surface Area 90.38
LOGP Value 4.00      (Computed with XLOGP3)
3.42      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 12
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q12866  
Entrez Gene IDNCBI Entrez Gene ID: 10461  
ASDInformation of known allosteric effects of PDB entries
 
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