Browse entries in the PDBbind-CN Database

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Related entries of code: 4uyf
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2ydwRCSB PDB    PDBbind153aa, >2YDW_1|Chains... at 100%
2yekRCSB PDB    PDBbind153aa, >2YEK_1|Chains... at 100%
3aqaRCSB PDB    PDBbind128aa, >3AQA_1|Chains... at 95%
4a9iRCSB PDB    PDBbind154aa, >4A9I_1|Chains... *
4a9mRCSB PDB    PDBbind154aa, >4A9M_1|Chains... at 100%
4a9nRCSB PDB    PDBbind154aa, >4A9N_1|Chains... at 100%
4aknRCSB PDB    PDBbind153aa, >4AKN_1|Chains... at 100%
4algRCSB PDB    PDBbind154aa, >4ALG_1|Chain... at 100%
4uyhRCSB PDB    PDBbind154aa, >4UYH_1|Chains... at 100%
6mo9RCSB PDB    PDBbind126aa, >6MO9_1|Chains... at 98%
6mo8RCSB PDB    PDBbind126aa, >6MO8_1|Chains... at 98%
6mo7RCSB PDB    PDBbind126aa, >6MO7_1|Chains... at 98%
6k05RCSB PDB    PDBbind122aa, >6K05_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4bjxRCSB PDB    PDBbind73B
4uygRCSB PDB    PDBbind73B
Entry Information
PDB ID4uyf
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameBROMODOMAIN-CONTAINING PROTEIN 2 BRD2 N-terminal bromodomain
Ligand Name73B
EC.Number E.C.-.-.-.-
Resolution 1.6(Å)
Affinity (Kd/Ki/IC50)Kd=25nM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2014) J.Med.Chem. Vol. 57: pp. 8111
Ligand Properties
Formula C25H23ClN2O3
Molecular Weight 434.915
Exact Mass 434.140
No. of atoms 54
No. of bonds 57
Polar Surface Area 69.64
LOGP Value 6.22      (Computed with XLOGP3)
6.14      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P25440  
Entrez Gene IDNCBI Entrez Gene ID: 6046  
ASDInformation of known allosteric effects of PDB entries
 
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