Browse entries in the PDBbind-CN Database

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Related entries of code: 4uyg
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4j1pRCSB PDB    PDBbind114aa, >4J1P_1|Chain... at 98%
4mr5RCSB PDB    PDBbind114aa, >4MR5_1|Chain... at 98%
4mr6RCSB PDB    PDBbind114aa, >4MR6_1|Chain... at 98%
4qevRCSB PDB    PDBbind114aa, >4QEV_1|Chain... at 97%
4qewRCSB PDB    PDBbind114aa, >4QEW_1|Chain... at 97%
5dw1RCSB PDB    PDBbind113aa, >5DW1_1|Chains... at 98%
5ek9RCSB PDB    PDBbind114aa, >5EK9_1|Chains... at 98%
5u6vRCSB PDB    PDBbind110aa, >5U6V_1|Chain... at 99%
6moaRCSB PDB    PDBbind110aa, >6MOA_1|Chain... at 100%
6k04RCSB PDB    PDBbind112aa, >6K04_1|Chain... at 100%
6ffgRCSB PDB    PDBbind115aa, >6FFG_1|Chain... at 97%
6fffRCSB PDB    PDBbind115aa, >6FFF_1|Chain... at 97%
6ffeRCSB PDB    PDBbind115aa, >6FFE_1|Chain... at 97%
6e6jRCSB PDB    PDBbind112aa, >6E6J_1|Chains... at 97%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4bjxRCSB PDB    PDBbind73B
4uyfRCSB PDB    PDBbind73B
Entry Information
PDB ID4uyg
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameBRD2 C-terminal bromodomain
Ligand Name73B
EC.Number E.C.-.-.-.-
Resolution 2.5(Å)
Affinity (Kd/Ki/IC50)Kd=25nM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2014) J.Med.Chem. Vol. 57: pp. 8111
Ligand Properties
Formula C25H23ClN2O3
Molecular Weight 434.915
Exact Mass 434.140
No. of atoms 54
No. of bonds 57
Polar Surface Area 69.64
LOGP Value 6.22      (Computed with XLOGP3)
6.14      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P25440  
Entrez Gene IDNCBI Entrez Gene ID: 6046  
ASDInformation of known allosteric effects of PDB entries
 
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