Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 5gvm
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4oytRCSB PDB    PDBbind442aa, >4OYT_1|Chains... *
4tmrRCSB PDB    PDBbind442aa, >4TMR_1|Chains... at 100%
4tn4RCSB PDB    PDBbind442aa, >4TN4_1|Chains... at 100%
5gvkRCSB PDB    PDBbind442aa, >5GVK_1|Chains... at 100%
5gvlRCSB PDB    PDBbind442aa, >5GVL_1|Chains... at 100%
5gvnRCSB PDB    PDBbind442aa, >5GVN_1|Chains... at 100%
5gvpRCSB PDB    PDBbind442aa, >5GVP_1|Chains... at 100%
5xmpRCSB PDB    PDBbind442aa, >5XMP_1|Chains... at 99%
5xmrRCSB PDB    PDBbind442aa, >5XMR_1|Chains... at 99%
5xmsRCSB PDB    PDBbind442aa, >5XMS_1|Chains... at 100%
5xmtRCSB PDB    PDBbind442aa, >5XMT_1|Chains... at 100%
5xmuRCSB PDB    PDBbind442aa, >5XMU_1|Chains... at 100%
5xmvRCSB PDB    PDBbind442aa, >5XMV_1|Chains... at 100%
5yfzRCSB PDB    PDBbind442aa, >5YFZ_1|Chains... at 100%
5yg2RCSB PDB    PDBbind442aa, >5YG2_1|Chains... at 100%
5yg3RCSB PDB    PDBbind442aa, >5YG3_1|Chains... at 100%
5yg4RCSB PDB    PDBbind442aa, >5YG4_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5gvm
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameSerine Hydroxymethyltransferase
Ligand NameG57
EC.Number E.C.-.-.-.-
Resolution 2.24(Å)
Affinity (Kd/Ki/IC50)Kd=186nM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) J. Med. Chem. Vol. 60: pp. 4840-4860
Ligand Properties
Formula C26H23F3N4O3
Molecular Weight 496.481
Exact Mass 496.172
No. of atoms 59
No. of bonds 62
Polar Surface Area 125.02
LOGP Value 7.08      (Computed with XLOGP3)
5.76      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): A5K8L9  
Entrez Gene IDNCBI Entrez Gene ID: 5473173  
ASDInformation of known allosteric effects of PDB entries

 
This site has been visited times since Nov 2007.


Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝e湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com