Browse entries in the PDBbind-CN Database

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Related entries of code: 5ia3
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5i9xRCSB PDB    PDBbind306aa, >5I9X_1|Chain... *
5i9yRCSB PDB    PDBbind306aa, >5I9Y_1|Chain... at 100%
5i9zRCSB PDB    PDBbind306aa, >5I9Z_1|Chain... at 100%
5ia0RCSB PDB    PDBbind306aa, >5IA0_1|Chains... at 100%
5ia1RCSB PDB    PDBbind306aa, >5IA1_1|Chain... at 100%
5ia2RCSB PDB    PDBbind306aa, >5IA2_1|Chain... at 100%
5ia4RCSB PDB    PDBbind306aa, >5IA4_1|Chain... at 100%
5ia5RCSB PDB    PDBbind306aa, >5IA5_1|Chain... at 100%
5njzRCSB PDB    PDBbind306aa, >5NJZ_1|Chain... at 100%
5nk2RCSB PDB    PDBbind306aa, >5NK2_1|Chain... at 100%
5nk3RCSB PDB    PDBbind306aa, >5NK3_1|Chain... at 100%
5nk4RCSB PDB    PDBbind306aa, >5NK4_1|Chain... at 100%
5nk6RCSB PDB    PDBbind306aa, >5NK6_1|Chain... at 100%
5nk7RCSB PDB    PDBbind306aa, >5NK7_1|Chain... at 100%
5nk8RCSB PDB    PDBbind306aa, >5NK8_1|Chain... at 100%
5nk9RCSB PDB    PDBbind306aa, >5NK9_1|Chain... at 100%
5nkaRCSB PDB    PDBbind306aa, >5NKA_1|Chain... at 100%
5nkbRCSB PDB    PDBbind306aa, >5NKB_1|Chain... at 100%
5nkcRCSB PDB    PDBbind306aa, >5NKC_1|Chain... at 100%
5nkdRCSB PDB    PDBbind306aa, >5NKD_1|Chain... at 100%
5nkgRCSB PDB    PDBbind306aa, >5NKG_1|Chain... at 100%
5nkhRCSB PDB    PDBbind306aa, >5NKH_1|Chain... at 100%
5nkiRCSB PDB    PDBbind306aa, >5NKI_1|Chain... at 100%
6fnfRCSB PDB    PDBbind306aa, >6FNF_1|Chain... at 100%
6fngRCSB PDB    PDBbind306aa, >6FNG_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5ia3
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameEphrin A2 (EphA2) Receptor Protein Kinase
Ligand NameP17
EC.Number E.C.2.7.10.1
Resolution 1.79(Å)
Affinity (Kd/Ki/IC50)Kd=46nM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) ACS Chem. Biol. Vol. 11: pp. 3400-3411
Ligand Properties
Formula C21H16Cl2N4OS
Molecular Weight 443.349
Exact Mass 442.042
No. of atoms 45
No. of bonds 48
Polar Surface Area 85.11
LOGP Value 5.41      (Computed with XLOGP3)
5.84      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P29317  
Entrez Gene IDNCBI Entrez Gene ID: 1969  
ASDInformation of known allosteric effects of PDB entries
 
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