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Related entries of code: 5m5q
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5jogRCSB PDB    PDBbind257aa, >5JOG_1|Chain... *
5johRCSB PDB    PDBbind257aa, >5JOH_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5m5q
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameCOP9 signalosome complex subunit 5
Ligand Name7K1
EC.Number E.C.3.4.-.-
Resolution 2.2(Å)
Affinity (Kd/Ki/IC50)IC50=0.09uM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) Angew. Chem. Int. Ed. Engl. Vol. 56: pp. 1294-1297
Ligand Properties
Formula C34H31N5O2
Molecular Weight 541.642
Exact Mass 541.248
No. of atoms 72
No. of bonds 78
Polar Surface Area 86.9
LOGP Value 5.41      (Computed with XLOGP3)
6.55      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 7
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 7
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q92905  
Entrez Gene IDNCBI Entrez Gene ID: 10987  
ASDInformation of known allosteric effects of PDB entries
 
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