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Browse entries in the PDBbind-CN Database

HEADER    DNA BINDING PROTEIN/DNA                 24-AUG-17   6ASD              
TITLE     ZINC FINGER REGION OF HUMAN TET1 IN COMPLEX WITH CPG DNA              
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3');        
COMPND   3 CHAIN: A, B;                                                         
COMPND   4 ENGINEERED: YES;                                                     
COMPND   5 MOL_ID: 2;                                                           
COMPND   6 MOLECULE: METHYLCYTOSINE DIOXYGENASE TET1;                           
COMPND   7 CHAIN: C;                                                            
COMPND   8 FRAGMENT: ZINC FINGER REGION (UNP RESIDUES 587-632);                 
COMPND   9 SYNONYM: CXXC-TYPE ZINC FINGER PROTEIN 6,LEUKEMIA-ASSOCIATED PROTEIN 
COMPND  10 WITH A CXXC DOMAIN,TEN-ELEVEN TRANSLOCATION 1 GENE PROTEIN;          
COMPND  11 EC: 1.14.11.-;                                                       
COMPND  12 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 SYNTHETIC: YES;                                                      
SOURCE   3 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT;                            
SOURCE   4 ORGANISM_TAXID: 32630;                                               
SOURCE   5 OTHER_DETAILS: SYNTHETIC;                                            
SOURCE   6 MOL_ID: 2;                                                           
SOURCE   7 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   8 ORGANISM_COMMON: HUMAN;                                              
SOURCE   9 ORGANISM_TAXID: 9606;                                                
SOURCE  10 GENE: TET1, CXXC6, KIAA1676, LCX;                                    
SOURCE  11 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
SOURCE  12 EXPRESSION_SYSTEM_TAXID: 562;                                        
SOURCE  13 EXPRESSION_SYSTEM_STRAIN: BL21(DE3)-V2R-PRARE2;                      
SOURCE  14 EXPRESSION_SYSTEM_PLASMID: PET28-MHL                                 
KEYWDS    ZINC FINGER, DNA-BINDING, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS    
KEYWDS   2 CONSORTIUM, SGC, DNA BINDING PROTEIN-DNA COMPLEX                     
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    K.LIU,C.XU,W.TEMPEL,J.R.WALKER,C.H.ARROWSMITH,C.BOUNTRA,A.M.EDWARDS,  
AUTHOR   2 J.MIN,STRUCTURAL GENOMICS CONSORTIUM (SGC)                           
REVDAT   3   10-JAN-18 6ASD    1       JRNL                                     
REVDAT   2   03-JAN-18 6ASD    1       JRNL                                     
REVDAT   1   18-OCT-17 6ASD    0                                                
JRNL        AUTH   C.XU,K.LIU,M.LEI,A.YANG,Y.LI,T.R.HUGHES,J.MIN                
JRNL        TITL   DNA SEQUENCE RECOGNITION OF HUMAN CXXC DOMAINS AND THEIR     
JRNL        TITL 2 STRUCTURAL DETERMINANTS.                                     
JRNL        REF    STRUCTURE                     V.  26    85 2018              
JRNL        REFN                   ISSN 1878-4186                               
JRNL        PMID   29276034                                                     
JRNL        DOI    10.1016/J.STR.2017.11.022                                    
REMARK   2                                                                      
REMARK   2 RESOLUTION.    1.85 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : REFMAC 5.8.0158                                      
REMARK   3   AUTHORS     : MURSHUDOV,VAGIN,DODSON                               
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : NULL                                          
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 1.85                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 36.72                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : 0.000                          
REMARK   3   COMPLETENESS FOR RANGE        (%) : 98.1                           
REMARK   3   NUMBER OF REFLECTIONS             : 10543                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : NULL                            
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.203                           
REMARK   3   R VALUE            (WORKING SET) : 0.202                           
REMARK   3   FREE R VALUE                     : 0.235                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 4.900                           
REMARK   3   FREE R VALUE TEST SET COUNT      : 539                             
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 20                           
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 1.85                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 1.90                         
REMARK   3   REFLECTION IN BIN     (WORKING SET) : 765                          
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 96.20                        
REMARK   3   BIN R VALUE           (WORKING SET) : 0.2410                       
REMARK   3   BIN FREE R VALUE SET COUNT          : 44                           
REMARK   3   BIN FREE R VALUE                    : 0.3120                       
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 348                                     
REMARK   3   NUCLEIC ACID ATOMS       : 486                                     
REMARK   3   HETEROGEN ATOMS          : 19                                      
REMARK   3   SOLVENT ATOMS            : 58                                      
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : NULL                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 36.23                          
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : -1.09000                                             
REMARK   3    B22 (A**2) : 0.37000                                              
REMARK   3    B33 (A**2) : 0.19000                                              
REMARK   3    B12 (A**2) : 0.00000                                              
REMARK   3    B13 (A**2) : 0.30000                                              
REMARK   3    B23 (A**2) : 0.00000                                              
REMARK   3                                                                      
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.                                 
REMARK   3   ESU BASED ON R VALUE                            (A): 0.140         
REMARK   3   ESU BASED ON FREE R VALUE                       (A): 0.131         
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A): 0.095         
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 5.580         
REMARK   3                                                                      
REMARK   3 CORRELATION COEFFICIENTS.                                            
REMARK   3   CORRELATION COEFFICIENT FO-FC      : 0.960                         
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE : 0.950                         
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT      
REMARK   3   BOND LENGTHS REFINED ATOMS        (A):   913 ; 0.013 ; 0.014       
REMARK   3   BOND LENGTHS OTHERS               (A):   619 ; 0.004 ; 0.020       
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES):  1322 ; 1.455 ; 1.460       
REMARK   3   BOND ANGLES OTHERS          (DEGREES):  1447 ; 1.336 ; 3.011       
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):    48 ; 4.799 ; 5.000       
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):    15 ;44.548 ;23.333       
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):    84 ;12.492 ;15.000       
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):     4 ; 6.978 ;15.000       
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):   122 ; 0.075 ; 0.200       
REMARK   3   GENERAL PLANES REFINED ATOMS      (A):   685 ; 0.012 ; 0.020       
REMARK   3   GENERAL PLANES OTHERS             (A):   199 ; 0.002 ; 0.020       
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND OTHERS            (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT      
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2):   182 ; 1.188 ; 2.210       
REMARK   3   MAIN-CHAIN BOND OTHER ATOMS    (A**2):   181 ; 1.187 ; 2.207       
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2):   227 ; 1.740 ; 3.305       
REMARK   3   MAIN-CHAIN ANGLE OTHER ATOMS   (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN BOND OTHER ATOMS    (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN ANGLE OTHER ATOMS   (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   LONG RANGE B REFINED ATOMS     (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   LONG RANGE B OTHER ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3 ANISOTROPIC THERMAL FACTOR RESTRAINTS.    COUNT   RMS   WEIGHT       
REMARK   3   RIGID-BOND RESTRAINTS          (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; FREE ATOMS         (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; BONDED ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS STATISTICS                                           
REMARK   3   NUMBER OF DIFFERENT NCS GROUPS : NULL                              
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : 3                                          
REMARK   3                                                                      
REMARK   3   TLS GROUP : 1                                                      
REMARK   3    NUMBER OF COMPONENTS GROUP : 1                                    
REMARK   3    COMPONENTS        C SSSEQI   TO  C SSSEQI                         
REMARK   3    RESIDUE RANGE :   A     1        A    12                          
REMARK   3    ORIGIN FOR THE GROUP (A): -65.5442  28.7234  11.3996              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0653 T22:   0.1101                                     
REMARK   3      T33:   0.0898 T12:   0.0580                                     
REMARK   3      T13:  -0.0012 T23:  -0.0071                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   7.7973 L22:   1.8113                                     
REMARK   3      L33:   0.6956 L12:  -2.0198                                     
REMARK   3      L13:  -0.7140 L23:  -0.5434                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.1440 S12:  -0.1623 S13:  -0.1890                       
REMARK   3      S21:  -0.0040 S22:   0.2018 S23:  -0.0208                       
REMARK   3      S31:   0.0541 S32:  -0.0592 S33:  -0.0578                       
REMARK   3                                                                      
REMARK   3   TLS GROUP : 2                                                      
REMARK   3    NUMBER OF COMPONENTS GROUP : 1                                    
REMARK   3    COMPONENTS        C SSSEQI   TO  C SSSEQI                         
REMARK   3    RESIDUE RANGE :   B     1        B    12                          
REMARK   3    ORIGIN FOR THE GROUP (A): -65.1088  29.6323   9.9697              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0510 T22:   0.1134                                     
REMARK   3      T33:   0.0436 T12:   0.0500                                     
REMARK   3      T13:  -0.0104 T23:   0.0080                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   7.5508 L22:   3.4103                                     
REMARK   3      L33:   1.2032 L12:  -3.0152                                     
REMARK   3      L13:  -1.3140 L23:   0.0749                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0500 S12:   0.2297 S13:  -0.2054                       
REMARK   3      S21:  -0.0835 S22:   0.0146 S23:   0.0660                       
REMARK   3      S31:   0.0214 S32:  -0.0134 S33:   0.0354                       
REMARK   3                                                                      
REMARK   3   TLS GROUP : 3                                                      
REMARK   3    NUMBER OF COMPONENTS GROUP : 1                                    
REMARK   3    COMPONENTS        C SSSEQI   TO  C SSSEQI                         
REMARK   3    RESIDUE RANGE :   C   586        C   630                          
REMARK   3    ORIGIN FOR THE GROUP (A): -64.8468  39.1645  18.8573              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1420 T22:   0.0947                                     
REMARK   3      T33:   0.0142 T12:   0.0975                                     
REMARK   3      T13:  -0.0105 T23:  -0.0047                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   3.8397 L22:   6.8408                                     
REMARK   3      L33:   4.8100 L12:   2.4037                                     
REMARK   3      L13:  -0.9787 L23:  -1.4168                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0258 S12:  -0.1784 S13:   0.0632                       
REMARK   3      S21:   0.6348 S22:   0.1264 S23:  -0.1477                       
REMARK   3      S31:  -0.2363 S32:  -0.0045 S33:  -0.1522                       
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED : NULL                                                 
REMARK   3   PARAMETERS FOR MASK CALCULATION                                    
REMARK   3   VDW PROBE RADIUS   : 1.20                                          
REMARK   3   ION PROBE RADIUS   : 0.80                                          
REMARK   3   SHRINKAGE RADIUS   : 0.80                                          
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: COOT WAS USED FOR INTERACTIVE MODEL       
REMARK   3  BUILDING. MODEL GEOMETRY WAS ASSESSED ON THE MOLPROBITY SERVER.     
REMARK   4                                                                      
REMARK   4 6ASD COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 25-AUG-17.                  
REMARK 100 THE DEPOSITION ID IS D_1000229396.                                   
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 20-JUN-13                          
REMARK 200  TEMPERATURE           (KELVIN) : 100                                
REMARK 200  PH                             : 7.5                                
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : APS                                
REMARK 200  BEAMLINE                       : 19-ID                              
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.97918                            
REMARK 200  MONOCHROMATOR                  : NULL                               
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : CCD                                
REMARK 200  DETECTOR MANUFACTURER          : ADSC QUANTUM 315R                  
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : XDS                                
REMARK 200  DATA SCALING SOFTWARE          : AIMLESS 0.5.32                     
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 11082                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 1.850                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 36.720                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : NULL                               
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 98.3                               
REMARK 200  DATA REDUNDANCY                : 3.600                              
REMARK 200  R MERGE                    (I) : 0.03800                            
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 22.1000                            
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.85                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 1.89                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 95.7                               
REMARK 200  DATA REDUNDANCY IN SHELL       : 3.80                               
REMARK 200  R MERGE FOR SHELL          (I) : 0.42300                            
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : NULL                               
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT        
REMARK 200 SOFTWARE USED: PHASER                                                
REMARK 200 STARTING MODEL: PDB ENTRY 4HP3                                       
REMARK 200                                                                      
REMARK 200 REMARK: NULL                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 52.20                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.60                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 25% PEG-3350, 0.2 M AMMONIUM ACETATE,    
REMARK 280  0.1 M HEPES, PH 7.5, VAPOR DIFFUSION, TEMPERATURE 291K              
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1                          
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,Y,-Z                                                 
REMARK 290       3555   X+1/2,Y+1/2,Z                                           
REMARK 290       4555   -X+1/2,Y+1/2,-Z                                         
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   3  1.000000  0.000000  0.000000       36.75100            
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000       15.97550            
REMARK 290   SMTRY3   3  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   4 -1.000000  0.000000  0.000000       36.75100            
REMARK 290   SMTRY2   4  0.000000  1.000000  0.000000       15.97550            
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC                          
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC                   
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 3010 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 6740 ANGSTROM**2                        
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -14.0 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C                               
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     PRO C   631                                                      
REMARK 465     SER C   632                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     GLY C 586    N                                                   
REMARK 470     GLU C 595    OE1  OE2                                            
REMARK 470     LYS C 600    CD   CE   NZ                                        
REMARK 470     LYS C 613    CD   CE   NZ                                        
REMARK 470     LYS C 621    NZ                                                  
REMARK 470     LYS C 630    CG   CD   CE   NZ                                   
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    ARG C 590   NE  -  CZ  -  NH1 ANGL. DEV. =   3.1 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN C 701  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 591   SG                                                     
REMARK 620 2 CYS C 594   SG  101.6                                              
REMARK 620 3 CYS C 597   SG  122.7  95.5                                        
REMARK 620 4 CYS C 624   SG  113.2 113.8 108.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN C 702  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 603   SG                                                     
REMARK 620 2 CYS C 606   SG  108.5                                              
REMARK 620 3 CYS C 609   SG  117.8 106.0                                        
REMARK 620 4 CYS C 619   SG  103.5 118.9 102.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN C 701                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN C 702                  
DBREF  6ASD A    1    12  PDB    6ASD     6ASD             1     12             
DBREF  6ASD B    1    12  PDB    6ASD     6ASD             1     12             
DBREF  6ASD C  587   632  UNP    Q8NFU7   TET1_HUMAN     587    632             
SEQADV 6ASD GLY C  586  UNP  Q8NFU7              EXPRESSION TAG                 
SEQRES   1 A   12   DG  DC  DC  DA  DC  DC  DG  DG  DT  DG  DG  DC              
SEQRES   1 B   12   DG  DC  DC  DA  DC  DC  DG  DG  DT  DG  DG  DC              
SEQRES   1 C   47  GLY LYS ARG LYS ARG CYS GLY VAL CYS GLU PRO CYS GLN          
SEQRES   2 C   47  GLN LYS THR ASN CYS GLY GLU CYS THR TYR CYS LYS ASN          
SEQRES   3 C   47  ARG LYS ASN SER HIS GLN ILE CYS LYS LYS ARG LYS CYS          
SEQRES   4 C   47  GLU GLU LEU LYS LYS LYS PRO SER                              
HET    UNX  A 101       1                                                       
HET    UNX  A 102       1                                                       
HET    UNX  A 103       1                                                       
HET    UNX  B 101       1                                                       
HET    UNX  B 102       1                                                       
HET    UNX  B 103       1                                                       
HET    UNX  B 104       1                                                       
HET    UNX  B 105       1                                                       
HET    UNX  B 106       1                                                       
HET     ZN  C 701       1                                                       
HET     ZN  C 702       1                                                       
HET    UNX  C 703       1                                                       
HET    UNX  C 704       1                                                       
HET    UNX  C 705       1                                                       
HET    UNX  C 706       1                                                       
HET    UNX  C 707       1                                                       
HET    UNX  C 708       1                                                       
HET    UNX  C 709       1                                                       
HET    UNX  C 710       1                                                       
HETNAM     UNX UNKNOWN ATOM OR ION                                              
HETNAM      ZN ZINC ION                                                         
FORMUL   4  UNX    17(X)                                                        
FORMUL  13   ZN    2(ZN 2+)                                                     
FORMUL  23  HOH   *58(H2 O)                                                     
HELIX    1 AA1 CYS C  594  GLN C  599  1                                   6    
HELIX    2 AA2 CYS C  606  ASN C  611  1                                   6    
HELIX    3 AA3 CYS C  624  LYS C  629  1                                   6    
LINK         SG  CYS C 591                ZN    ZN C 701     1555   1555  2.29  
LINK         SG  CYS C 594                ZN    ZN C 701     1555   1555  2.15  
LINK         SG  CYS C 597                ZN    ZN C 701     1555   1555  2.29  
LINK         SG  CYS C 603                ZN    ZN C 702     1555   1555  2.31  
LINK         SG  CYS C 606                ZN    ZN C 702     1555   1555  2.38  
LINK         SG  CYS C 609                ZN    ZN C 702     1555   1555  2.33  
LINK         SG  CYS C 619                ZN    ZN C 702     1555   1555  2.36  
LINK         SG  CYS C 624                ZN    ZN C 701     1555   1555  2.28  
SITE     1 AC1  5 CYS C 591  GLY C 592  CYS C 594  CYS C 597                    
SITE     2 AC1  5 CYS C 624                                                     
SITE     1 AC2  4 CYS C 603  CYS C 606  CYS C 609  CYS C 619                    
CRYST1   73.502   31.951   65.414  90.00 121.82  90.00 C 1 2 1       8          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.013605  0.000000  0.008442        0.00000                         
SCALE2      0.000000  0.031298  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.017991        0.00000                         
ATOM      1  O5'  DG A   1     -48.359  15.243  16.888  1.00 52.71           O  
ANISOU    1  O5'  DG A   1     4874   6476   8676   1615    896   1882       O  
ATOM      2  C5'  DG A   1     -49.665  15.803  17.079  1.00 49.28           C  
ANISOU    2  C5'  DG A   1     4531   6141   8052   1582    829   1814       C  
ATOM      3  C4'  DG A   1     -49.538  17.268  17.413  1.00 47.01           C  
ANISOU    3  C4'  DG A   1     4368   6189   7303   1577    631   1593       C  
ATOM      4  O4'  DG A   1     -49.054  17.978  16.247  1.00 42.80           O  
ANISOU    4  O4'  DG A   1     4019   5485   6758   1418    567   1226       O  
ATOM      5  C3'  DG A   1     -50.837  17.967  17.794  1.00 45.69           C  
ANISOU    5  C3'  DG A   1     4277   6184   6896   1574    554   1535       C  
ATOM      6  O3'  DG A   1     -50.466  19.067  18.628  1.00 48.20           O  
ANISOU    6  O3'  DG A   1     4585   6900   6828   1660    389   1438       O  
ATOM      7  C2'  DG A   1     -51.366  18.422  16.446  1.00 42.71           C  
ANISOU    7  C2'  DG A   1     4115   5517   6595   1373    532   1189       C  
ATOM      8  C1'  DG A   1     -50.081  18.833  15.737  1.00 40.86           C  
ANISOU    8  C1'  DG A   1     3944   5214   6366   1307    491    986       C  
ATOM      9  N9   DG A   1     -50.099  18.692  14.285  1.00 38.44           N  
ANISOU    9  N9   DG A   1     3764   4604   6235   1165    546    753       N  
ATOM     10  C8   DG A   1     -50.513  17.603  13.551  1.00 39.94           C  
ANISOU   10  C8   DG A   1     3933   4506   6733   1118    672    740       C  
ATOM     11  N7   DG A   1     -50.359  17.765  12.264  1.00 38.91           N  
ANISOU   11  N7   DG A   1     3915   4229   6638   1018    682    467       N  
ATOM     12  C5   DG A   1     -49.824  19.039  12.140  1.00 37.52           C  
ANISOU   12  C5   DG A   1     3835   4227   6191    995    577    354       C  
ATOM     13  C6   DG A   1     -49.454  19.773  10.980  1.00 35.01           C  
ANISOU   13  C6   DG A   1     3626   3888   5785    923    562    133       C  
ATOM     14  O6   DG A   1     -49.515  19.423   9.794  1.00 36.12           O  
ANISOU   14  O6   DG A   1     3813   3907   6001    880    629    -33       O  
ATOM     15  N1   DG A   1     -48.918  21.012  11.309  1.00 34.03           N  
ANISOU   15  N1   DG A   1     3522   3926   5482    924    461    120       N  
ATOM     16  C2   DG A   1     -48.771  21.497  12.590  1.00 35.08           C  
ANISOU   16  C2   DG A   1     3582   4242   5503    987    360    223       C  
ATOM     17  N2   DG A   1     -48.253  22.728  12.704  1.00 32.52           N  
ANISOU   17  N2   DG A   1     3256   4021   5079    970    258    125       N  
ATOM     18  N3   DG A   1     -49.114  20.823  13.680  1.00 36.08           N  
ANISOU   18  N3   DG A   1     3614   4463   5628   1075    364    410       N  
ATOM     19  C4   DG A   1     -49.628  19.611  13.382  1.00 36.13           C  
ANISOU   19  C4   DG A   1     3598   4290   5839   1074    486    500       C  
ATOM     20  P    DC A   2     -51.572  20.009  19.286  1.00 53.07           P  
ANISOU   20  P    DC A   2     5247   7793   7122   1705    281   1345       P  
ATOM     21  OP1  DC A   2     -51.234  20.145  20.728  1.00 53.86           O  
ANISOU   21  OP1  DC A   2     5153   8395   6916   1938    212   1516       O  
ATOM     22  OP2  DC A   2     -52.916  19.518  18.862  1.00 51.02           O  
ANISOU   22  OP2  DC A   2     5047   7304   7032   1637    387   1432       O  
ATOM     23  O5'  DC A   2     -51.278  21.423  18.625  1.00 47.30           O  
ANISOU   23  O5'  DC A   2     4686   7014   6270   1561    125    909       O  
ATOM     24  C5'  DC A   2     -49.961  21.980  18.732  1.00 47.89           C  
ANISOU   24  C5'  DC A   2     4709   7192   6293   1572     20    757       C  
ATOM     25  C4'  DC A   2     -49.907  23.328  18.063  1.00 44.77           C  
ANISOU   25  C4'  DC A   2     4442   6690   5879   1431    -94    394       C  
ATOM     26  O4'  DC A   2     -49.963  23.156  16.627  1.00 42.24           O  
ANISOU   26  O4'  DC A   2     4269   5991   5786   1265      4    333       O  
ATOM     27  C3'  DC A   2     -51.055  24.267  18.422  1.00 44.72           C  
ANISOU   27  C3'  DC A   2     4492   6811   5687   1434   -179    235       C  
ATOM     28  O3'  DC A   2     -50.511  25.583  18.591  1.00 46.71           O  
ANISOU   28  O3'  DC A   2     4708   7149   5889   1412   -338    -78       O  
ATOM     29  C2'  DC A   2     -52.004  24.146  17.234  1.00 40.86           C  
ANISOU   29  C2'  DC A   2     4178   5995   5349   1281    -78    224       C  
ATOM     30  C1'  DC A   2     -51.062  23.874  16.077  1.00 38.08           C  
ANISOU   30  C1'  DC A   2     3877   5369   5219   1169    -12    186       C  
ATOM     31  N1   DC A   2     -51.596  23.064  14.954  1.00 36.98           N  
ANISOU   31  N1   DC A   2     3841   4957   5251   1074    120    240       N  
ATOM     32  C2   DC A   2     -51.396  23.514  13.636  1.00 35.22           C  
ANISOU   32  C2   DC A   2     3723   4544   5115    954    146     82       C  
ATOM     33  O2   DC A   2     -50.851  24.608  13.451  1.00 34.80           O  
ANISOU   33  O2   DC A   2     3671   4513   5038    922     75    -48       O  
ATOM     34  N3   DC A   2     -51.823  22.751  12.603  1.00 34.67           N  
ANISOU   34  N3   DC A   2     3719   4286   5165    891    249     75       N  
ATOM     35  C4   DC A   2     -52.402  21.574  12.838  1.00 35.25           C  
ANISOU   35  C4   DC A   2     3750   4286   5355    920    325    201       C  
ATOM     36  N4   DC A   2     -52.809  20.862  11.787  1.00 36.12           N  
ANISOU   36  N4   DC A   2     3899   4205   5617    854    405    115       N  
ATOM     37  C5   DC A   2     -52.600  21.079  14.166  1.00 37.15           C  
ANISOU   37  C5   DC A   2     3873   4666   5576   1033    325    424       C  
ATOM     38  C6   DC A   2     -52.178  21.848  15.184  1.00 37.35           C  
ANISOU   38  C6   DC A   2     3842   4949   5399   1119    222    445       C  
ATOM     39  P    DC A   3     -51.352  26.729  19.313  1.00 48.97           P  
ANISOU   39  P    DC A   3     4973   7650   5982   1464   -467   -317       P  
ATOM     40  OP1  DC A   3     -50.388  27.678  19.905  1.00 51.55           O  
ANISOU   40  OP1  DC A   3     5146   8148   6289   1510   -644   -615       O  
ATOM     41  OP2  DC A   3     -52.388  26.108  20.157  1.00 46.34           O  
ANISOU   41  OP2  DC A   3     4612   7574   5421   1609   -418   -107       O  
ATOM     42  O5'  DC A   3     -52.089  27.448  18.102  1.00 45.02           O  
ANISOU   42  O5'  DC A   3     4644   6799   5660   1280   -420   -438       O  
ATOM     43  C5'  DC A   3     -51.335  28.171  17.114  1.00 43.40           C  
ANISOU   43  C5'  DC A   3     4463   6324   5700   1143   -429   -584       C  
ATOM     44  C4'  DC A   3     -52.263  28.737  16.064  1.00 40.20           C  
ANISOU   44  C4'  DC A   3     4195   5679   5398   1018   -362   -610       C  
ATOM     45  O4'  DC A   3     -52.602  27.704  15.107  1.00 36.87           O  
ANISOU   45  O4'  DC A   3     3897   5098   5011    957   -218   -405       O  
ATOM     46  C3'  DC A   3     -53.600  29.260  16.591  1.00 40.36           C  
ANISOU   46  C3'  DC A   3     4246   5812   5275   1055   -399   -681       C  
ATOM     47  O3'  DC A   3     -54.035  30.332  15.761  1.00 41.51           O  
ANISOU   47  O3'  DC A   3     4438   5749   5585    948   -389   -790       O  
ATOM     48  C2'  DC A   3     -54.537  28.092  16.350  1.00 39.28           C  
ANISOU   48  C2'  DC A   3     4216   5662   5045   1058   -281   -434       C  
ATOM     49  C1'  DC A   3     -54.000  27.621  15.000  1.00 36.97           C  
ANISOU   49  C1'  DC A   3     4002   5109   4935    941   -181   -357       C  
ATOM     50  N1   DC A   3     -54.350  26.264  14.525  1.00 35.82           N  
ANISOU   50  N1   DC A   3     3915   4875   4817    926    -65   -170       N  
ATOM     51  C2   DC A   3     -54.302  26.016  13.146  1.00 33.73           C  
ANISOU   51  C2   DC A   3     3734   4408   4671    824     17   -179       C  
ATOM     52  O2   DC A   3     -53.937  26.925  12.384  1.00 34.26           O  
ANISOU   52  O2   DC A   3     3820   4403   4793    765      8   -273       O  
ATOM     53  N3   DC A   3     -54.657  24.798  12.678  1.00 32.19           N  
ANISOU   53  N3   DC A   3     3567   4115   4547    808    108    -88       N  
ATOM     54  C4   DC A   3     -55.048  23.847  13.527  1.00 33.65           C  
ANISOU   54  C4   DC A   3     3690   4349   4746    879    137     64       C  
ATOM     55  N4   DC A   3     -55.379  22.656  13.020  1.00 34.81           N  
ANISOU   55  N4   DC A   3     3828   4338   5061    852    232    131       N  
ATOM     56  C5   DC A   3     -55.115  24.072  14.935  1.00 35.86           C  
ANISOU   56  C5   DC A   3     3881   4859   4884    998     77    154       C  
ATOM     57  C6   DC A   3     -54.778  25.290  15.385  1.00 36.57           C  
ANISOU   57  C6   DC A   3     3957   5091   4846   1021    -33      3       C  
ATOM     58  P    DA A   4     -53.936  31.836  16.263  1.00 45.53           P  
ANISOU   58  P    DA A   4     4816   6257   6224    958   -511  -1087       P  
ATOM     59  OP1  DA A   4     -52.582  32.053  16.776  1.00 43.49           O  
ANISOU   59  OP1  DA A   4     4399   6057   6068    993   -614  -1245       O  
ATOM     60  OP2  DA A   4     -55.122  32.085  17.130  1.00 43.40           O  
ANISOU   60  OP2  DA A   4     4553   6182   5754   1046   -557  -1170       O  
ATOM     61  O5'  DA A   4     -54.081  32.638  14.891  1.00 41.42           O  
ANISOU   61  O5'  DA A   4     4336   5420   5981    823   -421  -1037       O  
ATOM     62  C5'  DA A   4     -53.028  32.666  13.919  1.00 39.78           C  
ANISOU   62  C5'  DA A   4     4097   5025   5991    752   -354   -944       C  
ATOM     63  C4'  DA A   4     -53.585  32.705  12.511  1.00 37.39           C  
ANISOU   63  C4'  DA A   4     3896   4571   5739    676   -212   -742       C  
ATOM     64  O4'  DA A   4     -54.187  31.435  12.158  1.00 35.65           O  
ANISOU   64  O4'  DA A   4     3831   4438   5273    680   -142   -592       O  
ATOM     65  C3'  DA A   4     -54.660  33.759  12.231  1.00 37.60           C  
ANISOU   65  C3'  DA A   4     3911   4513   5859    649   -194   -757       C  
ATOM     66  O3'  DA A   4     -54.420  34.204  10.899  1.00 37.90           O  
ANISOU   66  O3'  DA A   4     3921   4401   6079    599    -72   -575       O  
ATOM     67  C2'  DA A   4     -55.960  32.984  12.387  1.00 36.11           C  
ANISOU   67  C2'  DA A   4     3878   4466   5376    669   -179   -688       C  
ATOM     68  C1'  DA A   4     -55.583  31.573  11.933  1.00 35.59           C  
ANISOU   68  C1'  DA A   4     3909   4452   5160    665   -117   -551       C  
ATOM     69  N9   DA A   4     -56.225  30.465  12.628  1.00 35.63           N  
ANISOU   69  N9   DA A   4     3988   4595   4951    711   -132   -514       N  
ATOM     70  C8   DA A   4     -56.482  30.329  13.971  1.00 37.14           C  
ANISOU   70  C8   DA A   4     4138   4955   5016    800   -211   -579       C  
ATOM     71  N7   DA A   4     -56.999  29.167  14.294  1.00 37.00           N  
ANISOU   71  N7   DA A   4     4169   5027   4863    840   -173   -445       N  
ATOM     72  C5   DA A   4     -57.044  28.477  13.091  1.00 32.35           C  
ANISOU   72  C5   DA A   4     3659   4293   4340    759    -81   -347       C  
ATOM     73  C6   DA A   4     -57.493  27.190  12.758  1.00 31.75           C  
ANISOU   73  C6   DA A   4     3626   4178   4258    746    -10   -231       C  
ATOM     74  N6   DA A   4     -57.986  26.327  13.645  1.00 32.71           N  
ANISOU   74  N6   DA A   4     3711   4380   4334    815      3   -114       N  
ATOM     75  N1   DA A   4     -57.426  26.816  11.460  1.00 31.19           N  
ANISOU   75  N1   DA A   4     3607   3989   4254    673     53   -240       N  
ATOM     76  C2   DA A   4     -56.935  27.686  10.567  1.00 30.08           C  
ANISOU   76  C2   DA A   4     3474   3809   4146    633     63   -293       C  
ATOM     77  N3   DA A   4     -56.486  28.925  10.761  1.00 31.89           N  
ANISOU   77  N3   DA A   4     3652   4036   4427    637     23   -337       N  
ATOM     78  C4   DA A   4     -56.563  29.261  12.058  1.00 33.45           C  
ANISOU   78  C4   DA A   4     3800   4313   4594    692    -58   -393       C  
ATOM     79  P    DC A   5     -55.311  35.318  10.224  1.00 38.78           P  
ANISOU   79  P    DC A   5     3980   4400   6355    576     -2   -475       P  
ATOM     80  OP1  DC A   5     -54.477  35.971   9.197  1.00 38.77           O  
ANISOU   80  OP1  DC A   5     3837   4249   6644    561    108   -292       O  
ATOM     81  OP2  DC A   5     -55.935  36.173  11.290  1.00 39.09           O  
ANISOU   81  OP2  DC A   5     3944   4404   6502    593   -103   -698       O  
ATOM     82  O5'  DC A   5     -56.490  34.463   9.577  1.00 36.57           O  
ANISOU   82  O5'  DC A   5     3881   4271   5741    575     55   -331       O  
ATOM     83  C5'  DC A   5     -56.196  33.622   8.451  1.00 37.17           C  
ANISOU   83  C5'  DC A   5     4027   4423   5670    574    148   -172       C  
ATOM     84  C4'  DC A   5     -57.415  32.837   8.045  1.00 36.35           C  
ANISOU   84  C4'  DC A   5     4059   4458   5291    570    160   -134       C  
ATOM     85  O4'  DC A   5     -57.658  31.798   9.024  1.00 34.75           O  
ANISOU   85  O4'  DC A   5     3949   4311   4943    573     84   -254       O  
ATOM     86  C3'  DC A   5     -58.718  33.659   7.958  1.00 37.48           C  
ANISOU   86  C3'  DC A   5     4191   4608   5439    565    162    -81       C  
ATOM     87  O3'  DC A   5     -59.565  33.247   6.891  1.00 41.37           O  
ANISOU   87  O3'  DC A   5     4739   5240   5737    568    214     31       O  
ATOM     88  C2'  DC A   5     -59.498  33.185   9.155  1.00 36.48           C  
ANISOU   88  C2'  DC A   5     4145   4523   5191    566     68   -222       C  
ATOM     89  C1'  DC A   5     -59.046  31.733   9.184  1.00 33.72           C  
ANISOU   89  C1'  DC A   5     3879   4240   4691    566     63   -249       C  
ATOM     90  N1   DC A   5     -59.360  30.981  10.404  1.00 33.34           N  
ANISOU   90  N1   DC A   5     3872   4246   4550    593     -2   -323       N  
ATOM     91  C2   DC A   5     -59.829  29.661  10.276  1.00 31.63           C  
ANISOU   91  C2   DC A   5     3721   4069   4224    585     16   -286       C  
ATOM     92  O2   DC A   5     -59.874  29.146   9.151  1.00 31.20           O  
ANISOU   92  O2   DC A   5     3695   4011   4145    551     66   -265       O  
ATOM     93  N3   DC A   5     -60.192  28.979  11.381  1.00 29.73           N  
ANISOU   93  N3   DC A   5     3481   3882   3930    629    -13   -276       N  
ATOM     94  C4   DC A   5     -60.127  29.567  12.578  1.00 33.02           C  
ANISOU   94  C4   DC A   5     3849   4379   4318    697    -72   -325       C  
ATOM     95  N4   DC A   5     -60.483  28.851  13.643  1.00 33.05           N  
ANISOU   95  N4   DC A   5     3828   4498   4229    775    -84   -265       N  
ATOM     96  C5   DC A   5     -59.653  30.905  12.739  1.00 32.95           C  
ANISOU   96  C5   DC A   5     3777   4343   4398    703   -118   -444       C  
ATOM     97  C6   DC A   5     -59.290  31.569  11.635  1.00 32.28           C  
ANISOU   97  C6   DC A   5     3680   4137   4445    641    -75   -426       C  
ATOM     98  P    DC A   6     -59.712  34.106   5.584  1.00 42.16           P  
ANISOU   98  P    DC A   6     4733   5408   5877    605    323    260       P  
ATOM     99  OP1  DC A   6     -58.368  34.269   5.019  1.00 47.49           O  
ANISOU   99  OP1  DC A   6     5316   6054   6675    639    404    357       O  
ATOM    100  OP2  DC A   6     -60.540  35.293   5.914  1.00 40.23           O  
ANISOU  100  OP2  DC A   6     4410   5070   5805    603    325    329       O  
ATOM    101  O5'  DC A   6     -60.527  33.100   4.668  1.00 40.94           O  
ANISOU  101  O5'  DC A   6     4663   5488   5401    619    323    257       O  
ATOM    102  C5'  DC A   6     -59.913  31.897   4.201  1.00 39.02           C  
ANISOU  102  C5'  DC A   6     4478   5341   5007    629    326    152       C  
ATOM    103  C4'  DC A   6     -60.971  30.836   4.013  1.00 38.24           C  
ANISOU  103  C4'  DC A   6     4459   5358   4710    604    262     10       C  
ATOM    104  O4'  DC A   6     -61.300  30.260   5.292  1.00 33.86           O  
ANISOU  104  O4'  DC A   6     3982   4648   4234    546    185   -110       O  
ATOM    105  C3'  DC A   6     -62.287  31.316   3.403  1.00 38.12           C  
ANISOU  105  C3'  DC A   6     4409   5504   4569    619    252     96       C  
ATOM    106  O3'  DC A   6     -62.612  30.380   2.367  1.00 40.15           O  
ANISOU  106  O3'  DC A   6     4661   5990   4603    648    234    -26       O  
ATOM    107  C2'  DC A   6     -63.267  31.315   4.573  1.00 34.98           C  
ANISOU  107  C2'  DC A   6     4074   4964   4252    555    174     38       C  
ATOM    108  C1'  DC A   6     -62.710  30.221   5.472  1.00 32.85           C  
ANISOU  108  C1'  DC A   6     3876   4558   4044    519    134   -119       C  
ATOM    109  N1   DC A   6     -62.946  30.329   6.922  1.00 28.79           N  
ANISOU  109  N1   DC A   6     3395   3907   3635    500     88   -137       N  
ATOM    110  C2   DC A   6     -63.396  29.206   7.637  1.00 29.21           C  
ANISOU  110  C2   DC A   6     3487   3919   3691    480     50   -207       C  
ATOM    111  O2   DC A   6     -63.726  28.186   7.016  1.00 30.67           O  
ANISOU  111  O2   DC A   6     3671   4131   3848    455     44   -282       O  
ATOM    112  N3   DC A   6     -63.527  29.289   8.976  1.00 28.15           N  
ANISOU  112  N3   DC A   6     3358   3733   3604    503     23   -191       N  
ATOM    113  C4   DC A   6     -63.173  30.406   9.612  1.00 27.39           C  
ANISOU  113  C4   DC A   6     3235   3618   3550    537     12   -186       C  
ATOM    114  N4   DC A   6     -63.311  30.439  10.935  1.00 28.73           N  
ANISOU  114  N4   DC A   6     3394   3808   3715    587    -23   -210       N  
ATOM    115  C5   DC A   6     -62.692  31.552   8.914  1.00 26.77           C  
ANISOU  115  C5   DC A   6     3110   3513   3546    534     42   -155       C  
ATOM    116  C6   DC A   6     -62.582  31.466   7.587  1.00 28.38           C  
ANISOU  116  C6   DC A   6     3304   3774   3702    520     92    -93       C  
ATOM    117  P    DG A   7     -63.648  30.735   1.278  1.00 44.08           P  
ANISOU  117  P    DG A   7     5076   6786   4883    706    229     51       P  
ATOM    118  OP1  DG A   7     -63.304  29.930   0.058  1.00 45.66           O  
ANISOU  118  OP1  DG A   7     5226   7279   4843    787    235    -96       O  
ATOM    119  OP2  DG A   7     -63.817  32.207   1.195  1.00 38.85           O  
ANISOU  119  OP2  DG A   7     4326   6131   4302    751    306    360       O  
ATOM    120  O5'  DG A   7     -65.025  30.191   1.868  1.00 41.56           O  
ANISOU  120  O5'  DG A   7     4810   6399   4579    621    117    -88       O  
ATOM    121  C5'  DG A   7     -65.171  28.822   2.254  1.00 41.31           C  
ANISOU  121  C5'  DG A   7     4832   6256   4606    555     44   -349       C  
ATOM    122  C4'  DG A   7     -66.416  28.643   3.090  1.00 38.62           C  
ANISOU  122  C4'  DG A   7     4515   5787   4369    481    -25   -362       C  
ATOM    123  O4'  DG A   7     -66.173  29.082   4.451  1.00 36.08           O  
ANISOU  123  O4'  DG A   7     4259   5231   4217    454      0   -248       O  
ATOM    124  C3'  DG A   7     -67.645  29.430   2.625  1.00 40.55           C  
ANISOU  124  C3'  DG A   7     4700   6209   4498    498    -52   -240       C  
ATOM    125  O3'  DG A   7     -68.767  28.603   2.905  1.00 44.53           O  
ANISOU  125  O3'  DG A   7     5189   6662   5066    431   -139   -378       O  
ATOM    126  C2'  DG A   7     -67.675  30.607   3.579  1.00 35.90           C  
ANISOU  126  C2'  DG A   7     4144   5456   4039    497      0    -22       C  
ATOM    127  C1'  DG A   7     -67.261  29.893   4.840  1.00 34.18           C  
ANISOU  127  C1'  DG A   7     4007   4994   3985    447    -15   -120       C  
ATOM    128  N9   DG A   7     -66.845  30.703   5.975  1.00 30.54           N  
ANISOU  128  N9   DG A   7     3579   4374   3650    459     16    -26       N  
ATOM    129  C8   DG A   7     -66.314  31.974   5.976  1.00 30.11           C  
ANISOU  129  C8   DG A   7     3487   4289   3663    497     70     92       C  
ATOM    130  N7   DG A   7     -65.999  32.394   7.172  1.00 29.25           N  
ANISOU  130  N7   DG A   7     3395   4033   3683    503     64     66       N  
ATOM    131  C5   DG A   7     -66.383  31.354   8.011  1.00 28.52           C  
ANISOU  131  C5   DG A   7     3359   3915   3562    485     17    -19       C  
ATOM    132  C6   DG A   7     -66.343  31.249   9.426  1.00 27.08           C  
ANISOU  132  C6   DG A   7     3193   3673   3423    516     -4    -57       C  
ATOM    133  O6   DG A   7     -65.898  32.063  10.250  1.00 28.04           O  
ANISOU  133  O6   DG A   7     3290   3756   3607    560    -10    -95       O  
ATOM    134  N1   DG A   7     -66.851  30.028   9.862  1.00 27.96           N  
ANISOU  134  N1   DG A   7     3321   3789   3512    508    -19    -57       N  
ATOM    135  C2   DG A   7     -67.307  29.021   9.038  1.00 27.85           C  
ANISOU  135  C2   DG A   7     3299   3781   3499    454    -26    -80       C  
ATOM    136  N2   DG A   7     -67.746  27.905   9.637  1.00 29.28           N  
ANISOU  136  N2   DG A   7     3454   3908   3762    450    -26    -60       N  
ATOM    137  N3   DG A   7     -67.359  29.113   7.725  1.00 29.45           N  
ANISOU  137  N3   DG A   7     3490   4057   3642    422    -32   -120       N  
ATOM    138  C4   DG A   7     -66.889  30.298   7.282  1.00 29.22           C  
ANISOU  138  C4   DG A   7     3453   4073   3575    449     -3    -62       C  
ATOM    139  P    DG A   8     -69.922  28.413   1.845  1.00 50.15           P  
ANISOU  139  P    DG A   8     5791   7646   5617    442   -226   -477       P  
ATOM    140  OP1  DG A   8     -69.335  27.877   0.626  1.00 50.84           O  
ANISOU  140  OP1  DG A   8     5811   7988   5518    505   -248   -681       O  
ATOM    141  OP2  DG A   8     -70.730  29.665   1.825  1.00 45.79           O  
ANISOU  141  OP2  DG A   8     5208   7198   4990    475   -203   -214       O  
ATOM    142  O5'  DG A   8     -70.830  27.281   2.514  1.00 45.20           O  
ANISOU  142  O5'  DG A   8     5141   6812   5219    343   -307   -647       O  
ATOM    143  C5'  DG A   8     -70.286  26.069   3.040  1.00 43.09           C  
ANISOU  143  C5'  DG A   8     4885   6302   5182    293   -305   -817       C  
ATOM    144  C4'  DG A   8     -71.077  25.663   4.264  1.00 42.41           C  
ANISOU  144  C4'  DG A   8     4794   5957   5360    230   -303   -716       C  
ATOM    145  O4'  DG A   8     -70.660  26.447   5.407  1.00 37.75           O  
ANISOU  145  O4'  DG A   8     4309   5259   4772    262   -220   -466       O  
ATOM    146  C3'  DG A   8     -72.584  25.874   4.149  1.00 42.66           C  
ANISOU  146  C3'  DG A   8     4744   6063   5400    198   -372   -676       C  
ATOM    147  O3'  DG A   8     -73.218  24.794   4.813  1.00 45.99           O  
ANISOU  147  O3'  DG A   8     5078   6245   6149    133   -388   -722       O  
ATOM    148  C2'  DG A   8     -72.811  27.203   4.850  1.00 38.75           C  
ANISOU  148  C2'  DG A   8     4335   5587   4798    241   -307   -380       C  
ATOM    149  C1'  DG A   8     -71.757  27.167   5.939  1.00 35.84           C  
ANISOU  149  C1'  DG A   8     4063   5033   4521    264   -223   -293       C  
ATOM    150  N9   DG A   8     -71.252  28.467   6.372  1.00 32.99           N  
ANISOU  150  N9   DG A   8     3782   4702   4047    322   -162   -127       N  
ATOM    151  C8   DG A   8     -70.815  29.506   5.581  1.00 32.28           C  
ANISOU  151  C8   DG A   8     3699   4757   3806    363   -139    -71       C  
ATOM    152  N7   DG A   8     -70.388  30.530   6.271  1.00 29.25           N  
ANISOU  152  N7   DG A   8     3357   4303   3453    403    -82     53       N  
ATOM    153  C5   DG A   8     -70.544  30.139   7.595  1.00 30.08           C  
ANISOU  153  C5   DG A   8     3495   4266   3665    402    -78     57       C  
ATOM    154  C6   DG A   8     -70.234  30.821   8.798  1.00 28.01           C  
ANISOU  154  C6   DG A   8     3263   3928   3449    455    -45    108       C  
ATOM    155  O6   DG A   8     -69.767  31.952   8.942  1.00 28.07           O  
ANISOU  155  O6   DG A   8     3268   3919   3477    491    -17    131       O  
ATOM    156  N1   DG A   8     -70.527  30.043   9.919  1.00 27.79           N  
ANISOU  156  N1   DG A   8     3236   3853   3469    477    -44    125       N  
ATOM    157  C2   DG A   8     -71.051  28.777   9.881  1.00 27.41           C  
ANISOU  157  C2   DG A   8     3147   3765   3500    438    -56    128       C  
ATOM    158  N2   DG A   8     -71.292  28.197  11.062  1.00 27.97           N  
ANISOU  158  N2   DG A   8     3186   3802   3638    491    -23    225       N  
ATOM    159  N3   DG A   8     -71.325  28.125   8.766  1.00 29.05           N  
ANISOU  159  N3   DG A   8     3318   3979   3738    367    -96     37       N  
ATOM    160  C4   DG A   8     -71.059  28.860   7.671  1.00 30.02           C  
ANISOU  160  C4   DG A   8     3457   4214   3734    359   -113    -10       C  
ATOM    161  P    DT A   9     -74.792  24.636   4.757  1.00 48.57           P  
ANISOU  161  P    DT A   9     5274   6578   6600     80   -465   -718       P  
ATOM    162  OP1  DT A   9     -75.105  23.196   4.939  1.00 50.18           O  
ANISOU  162  OP1  DT A   9     5321   6528   7216      8   -493   -885       O  
ATOM    163  OP2  DT A   9     -75.310  25.374   3.592  1.00 47.73           O  
ANISOU  163  OP2  DT A   9     5132   6801   6202    105   -551   -794       O  
ATOM    164  O5'  DT A   9     -75.265  25.435   6.040  1.00 42.97           O  
ANISOU  164  O5'  DT A   9     4642   5787   5897    115   -375   -366       O  
ATOM    165  C5'  DT A   9     -74.772  25.062   7.333  1.00 42.46           C  
ANISOU  165  C5'  DT A   9     4616   5517   5997    145   -274   -200       C  
ATOM    166  C4'  DT A   9     -75.197  26.094   8.349  1.00 41.12           C  
ANISOU  166  C4'  DT A   9     4518   5393   5711    215   -207     67       C  
ATOM    167  O4'  DT A   9     -74.410  27.309   8.211  1.00 38.56           O  
ANISOU  167  O4'  DT A   9     4323   5198   5127    269   -185     87       O  
ATOM    168  C3'  DT A   9     -76.668  26.523   8.249  1.00 42.38           C  
ANISOU  168  C3'  DT A   9     4603   5619   5878    198   -241    162       C  
ATOM    169  O3'  DT A   9     -77.225  26.562   9.550  1.00 46.75           O  
ANISOU  169  O3'  DT A   9     5135   6098   6527    259   -156    401       O  
ATOM    170  C2'  DT A   9     -76.598  27.962   7.775  1.00 40.12           C  
ANISOU  170  C2'  DT A   9     4408   5522   5312    240   -245    203       C  
ATOM    171  C1'  DT A   9     -75.280  28.397   8.415  1.00 36.19           C  
ANISOU  171  C1'  DT A   9     4031   4987   4729    302   -174    229       C  
ATOM    172  N1   DT A   9     -74.653  29.615   7.858  1.00 34.28           N  
ANISOU  172  N1   DT A   9     3858   4859   4307    337   -162    231       N  
ATOM    173  C2   DT A   9     -74.162  30.550   8.748  1.00 32.85           C  
ANISOU  173  C2   DT A   9     3740   4641   4099    407    -98    311       C  
ATOM    174  O2   DT A   9     -74.162  30.388   9.961  1.00 33.19           O  
ANISOU  174  O2   DT A   9     3798   4623   4190    457    -61    359       O  
ATOM    175  N3   DT A   9     -73.613  31.661   8.162  1.00 30.90           N  
ANISOU  175  N3   DT A   9     3510   4448   3782    431    -77    329       N  
ATOM    176  C4   DT A   9     -73.529  31.941   6.813  1.00 31.03           C  
ANISOU  176  C4   DT A   9     3485   4597   3707    416    -95    335       C  
ATOM    177  O4   DT A   9     -73.030  32.998   6.443  1.00 33.04           O  
ANISOU  177  O4   DT A   9     3724   4879   3952    458    -45    420       O  
ATOM    178  C5   DT A   9     -74.072  30.927   5.936  1.00 33.78           C  
ANISOU  178  C5   DT A   9     3777   5056   3999    365   -172    233       C  
ATOM    179  C7   DT A   9     -74.016  31.142   4.455  1.00 36.17           C  
ANISOU  179  C7   DT A   9     4009   5605   4129    385   -203    215       C  
ATOM    180  C6   DT A   9     -74.606  29.831   6.494  1.00 33.83           C  
ANISOU  180  C6   DT A   9     3766   4959   4128    317   -209    159       C  
ATOM    181  P    DG A  10     -78.402  25.588   9.950  1.00 46.17           P  
ANISOU  181  P    DG A  10     4881   5885   6773    226   -144    516       P  
ATOM    182  OP1  DG A  10     -77.928  24.198   9.773  1.00 49.57           O  
ANISOU  182  OP1  DG A  10     5203   6120   7509    166   -151    397       O  
ATOM    183  OP2  DG A  10     -79.611  26.023   9.245  1.00 48.37           O  
ANISOU  183  OP2  DG A  10     5091   6255   7031    175   -223    492       O  
ATOM    184  O5'  DG A  10     -78.535  25.892  11.502  1.00 42.68           O  
ANISOU  184  O5'  DG A  10     4456   5461   6299    359    -13    815       O  
ATOM    185  C5'  DG A  10     -77.405  25.743  12.361  1.00 40.39           C  
ANISOU  185  C5'  DG A  10     4229   5177   5938    451     62    876       C  
ATOM    186  C4'  DG A  10     -77.491  26.711  13.515  1.00 38.99           C  
ANISOU  186  C4'  DG A  10     4113   5172   5530    602    136   1037       C  
ATOM    187  O4'  DG A  10     -77.107  28.051  13.108  1.00 35.70           O  
ANISOU  187  O4'  DG A  10     3836   4863   4863    604     87    881       O  
ATOM    188  C3'  DG A  10     -78.873  26.853  14.129  1.00 39.43           C  
ANISOU  188  C3'  DG A  10     4064   5274   5643    664    195   1260       C  
ATOM    189  O3'  DG A  10     -78.647  27.035  15.523  1.00 42.15           O  
ANISOU  189  O3'  DG A  10     4395   5777   5841    850    299   1440       O  
ATOM    190  C2'  DG A  10     -79.459  28.054  13.391  1.00 37.04           C  
ANISOU  190  C2'  DG A  10     3838   5042   5192    615    127   1146       C  
ATOM    191  C1'  DG A  10     -78.230  28.937  13.161  1.00 35.26           C  
ANISOU  191  C1'  DG A  10     3766   4882   4749    630     94    956       C  
ATOM    192  N9   DG A  10     -78.141  29.783  11.972  1.00 32.93           N  
ANISOU  192  N9   DG A  10     3535   4603   4372    548     21    810       N  
ATOM    193  C8   DG A  10     -78.469  29.468  10.673  1.00 32.26           C  
ANISOU  193  C8   DG A  10     3411   4503   4341    431    -61    722       C  
ATOM    194  N7   DG A  10     -78.108  30.389   9.817  1.00 31.61           N  
ANISOU  194  N7   DG A  10     3384   4500   4126    416    -92    646       N  
ATOM    195  C5   DG A  10     -77.475  31.351  10.594  1.00 29.23           C  
ANISOU  195  C5   DG A  10     3158   4203   3744    505    -30    663       C  
ATOM    196  C6   DG A  10     -76.825  32.559  10.220  1.00 28.57           C  
ANISOU  196  C6   DG A  10     3118   4140   3595    530    -15    623       C  
ATOM    197  O6   DG A  10     -76.717  33.062   9.094  1.00 29.32           O  
ANISOU  197  O6   DG A  10     3196   4289   3656    495    -36    627       O  
ATOM    198  N1   DG A  10     -76.303  33.223  11.328  1.00 26.94           N  
ANISOU  198  N1   DG A  10     2947   3905   3384    623     34    586       N  
ATOM    199  C2   DG A  10     -76.359  32.761  12.623  1.00 29.34           C  
ANISOU  199  C2   DG A  10     3249   4234   3664    706     65    597       C  
ATOM    200  N2   DG A  10     -75.789  33.534  13.563  1.00 29.17           N  
ANISOU  200  N2   DG A  10     3239   4243   3600    811     90    498       N  
ATOM    201  N3   DG A  10     -76.923  31.622  12.974  1.00 29.57           N  
ANISOU  201  N3   DG A  10     3236   4273   3726    702     74    702       N  
ATOM    202  C4   DG A  10     -77.453  30.971  11.919  1.00 30.63           C  
ANISOU  202  C4   DG A  10     3331   4362   3942    588     26    725       C  
ATOM    203  P    DG A  11     -79.867  27.078  16.542  1.00 48.70           P  
ANISOU  203  P    DG A  11     5094   6724   6683    991    409   1736       P  
ATOM    204  OP1  DG A  11     -79.425  26.436  17.798  1.00 53.10           O  
ANISOU  204  OP1  DG A  11     5552   7421   7203   1175    528   1977       O  
ATOM    205  OP2  DG A  11     -81.100  26.608  15.838  1.00 47.45           O  
ANISOU  205  OP2  DG A  11     4817   6397   6814    865    386   1816       O  
ATOM    206  O5'  DG A  11     -80.061  28.639  16.787  1.00 42.74           O  
ANISOU  206  O5'  DG A  11     4457   6153   5628   1074    391   1605       O  
ATOM    207  C5'  DG A  11     -78.974  29.451  17.280  1.00 38.74           C  
ANISOU  207  C5'  DG A  11     4060   5794   4863   1171    372   1415       C  
ATOM    208  C4'  DG A  11     -79.383  30.906  17.323  1.00 38.28           C  
ANISOU  208  C4'  DG A  11     4062   5818   4665   1217    357   1269       C  
ATOM    209  O4'  DG A  11     -79.170  31.541  16.024  1.00 35.91           O  
ANISOU  209  O4'  DG A  11     3853   5354   4436   1049    267   1088       O  
ATOM    210  C3'  DG A  11     -80.850  31.162  17.700  1.00 38.16           C  
ANISOU  210  C3'  DG A  11     3954   5868   4675   1291    429   1458       C  
ATOM    211  O3'  DG A  11     -80.884  32.025  18.844  1.00 39.88           O  
ANISOU  211  O3'  DG A  11     4157   6324   4670   1502    486   1394       O  
ATOM    212  C2'  DG A  11     -81.469  31.741  16.427  1.00 36.35           C  
ANISOU  212  C2'  DG A  11     3764   5470   4574   1121    360   1387       C  
ATOM    213  C1'  DG A  11     -80.291  32.363  15.705  1.00 34.93           C  
ANISOU  213  C1'  DG A  11     3703   5217   4348   1037    278   1131       C  
ATOM    214  N9   DG A  11     -80.394  32.420  14.243  1.00 33.05           N  
ANISOU  214  N9   DG A  11     3491   4848   4216    863    200   1085       N  
ATOM    215  C8   DG A  11     -80.914  31.462  13.406  1.00 32.41           C  
ANISOU  215  C8   DG A  11     3353   4692   4268    737    151   1155       C  
ATOM    216  N7   DG A  11     -80.833  31.787  12.145  1.00 32.79           N  
ANISOU  216  N7   DG A  11     3422   4716   4320    629     75   1064       N  
ATOM    217  C5   DG A  11     -80.183  33.013  12.148  1.00 30.64           C  
ANISOU  217  C5   DG A  11     3222   4464   3955    679     95    978       C  
ATOM    218  C6   DG A  11     -79.814  33.857  11.072  1.00 29.09           C  
ANISOU  218  C6   DG A  11     3044   4268   3741    630     65    927       C  
ATOM    219  O6   DG A  11     -79.993  33.687   9.865  1.00 29.70           O  
ANISOU  219  O6   DG A  11     3086   4392   3805    549      5    938       O  
ATOM    220  N1   DG A  11     -79.182  35.009  11.520  1.00 28.73           N  
ANISOU  220  N1   DG A  11     3028   4184   3702    706    115    859       N  
ATOM    221  C2   DG A  11     -78.959  35.326  12.836  1.00 30.19           C  
ANISOU  221  C2   DG A  11     3228   4372   3870    820    163    781       C  
ATOM    222  N2   DG A  11     -78.342  36.492  13.067  1.00 31.03           N  
ANISOU  222  N2   DG A  11     3327   4417   4044    875    190    654       N  
ATOM    223  N3   DG A  11     -79.328  34.564  13.852  1.00 32.42           N  
ANISOU  223  N3   DG A  11     3499   4730   4088    891    187    826       N  
ATOM    224  C4   DG A  11     -79.938  33.433  13.437  1.00 31.89           C  
ANISOU  224  C4   DG A  11     3400   4661   4056    813    162    958       C  
ATOM    225  P    DC A  12     -82.285  32.473  19.519  1.00 44.51           P  
ANISOU  225  P    DC A  12     4643   7053   5215   1648    587   1562       P  
ATOM    226  OP1  DC A  12     -82.013  32.803  20.927  1.00 44.89           O  
ANISOU  226  OP1  DC A  12     4635   7437   4983   1918    654   1511       O  
ATOM    227  OP2  DC A  12     -83.322  31.466  19.170  1.00 41.92           O  
ANISOU  227  OP2  DC A  12     4207   6609   5109   1567    634   1886       O  
ATOM    228  O5'  DC A  12     -82.619  33.840  18.764  1.00 41.92           O  
ANISOU  228  O5'  DC A  12     4385   6589   4952   1561    535   1351       O  
ATOM    229  C5'  DC A  12     -81.714  34.951  18.922  1.00 42.75           C  
ANISOU  229  C5'  DC A  12     4555   6711   4976   1607    489   1020       C  
ATOM    230  C4'  DC A  12     -81.900  35.985  17.837  1.00 41.23           C  
ANISOU  230  C4'  DC A  12     4401   6296   4967   1469    448    915       C  
ATOM    231  O4'  DC A  12     -81.677  35.435  16.528  1.00 37.57           O  
ANISOU  231  O4'  DC A  12     3989   5656   4628   1260    379    996       O  
ATOM    232  C3'  DC A  12     -83.292  36.585  17.758  1.00 41.57           C  
ANISOU  232  C3'  DC A  12     4373   6322   5098   1500    514   1052       C  
ATOM    233  O3'  DC A  12     -83.384  37.653  18.686  1.00 45.55           O  
ANISOU  233  O3'  DC A  12     4829   6930   5547   1681    568    852       O  
ATOM    234  C2'  DC A  12     -83.382  37.059  16.311  1.00 38.68           C  
ANISOU  234  C2'  DC A  12     4032   5741   4923   1314    461   1079       C  
ATOM    235  C1'  DC A  12     -82.220  36.355  15.601  1.00 37.78           C  
ANISOU  235  C1'  DC A  12     4000   5558   4796   1180    372   1013       C  
ATOM    236  N1   DC A  12     -82.608  35.605  14.391  1.00 35.31           N  
ANISOU  236  N1   DC A  12     3683   5177   4553   1014    314   1168       N  
ATOM    237  C2   DC A  12     -82.289  36.142  13.145  1.00 33.41           C  
ANISOU  237  C2   DC A  12     3456   4854   4382    906    265   1141       C  
ATOM    238  O2   DC A  12     -81.714  37.238  13.095  1.00 32.04           O  
ANISOU  238  O2   DC A  12     3287   4614   4270    941    290   1034       O  
ATOM    239  N3   DC A  12     -82.626  35.462  12.025  1.00 32.68           N  
ANISOU  239  N3   DC A  12     3339   4772   4303    781    194   1231       N  
ATOM    240  C4   DC A  12     -83.261  34.292  12.120  1.00 32.45           C  
ANISOU  240  C4   DC A  12     3266   4767   4294    739    165   1315       C  
ATOM    241  N4   DC A  12     -83.574  33.658  10.989  1.00 34.33           N  
ANISOU  241  N4   DC A  12     3454   5023   4567    618     74   1326       N  
ATOM    242  C5   DC A  12     -83.581  33.710  13.380  1.00 35.02           C  
ANISOU  242  C5   DC A  12     3567   5117   4622    833    232   1389       C  
ATOM    243  C6   DC A  12     -83.247  34.398  14.480  1.00 35.48           C  
ANISOU  243  C6   DC A  12     3657   5231   4591    981    308   1329       C  
TER     244       DC A  12                                                      
ATOM    245  O5'  DG B   1     -83.319  40.060   2.873  1.00 52.76           O  
ANISOU  245  O5'  DG B   1     5157   8759   6128   1860   -877   1377       O  
ATOM    246  C5'  DG B   1     -81.929  40.288   2.591  1.00 48.60           C  
ANISOU  246  C5'  DG B   1     4795   8219   5450   1878   -746   1503       C  
ATOM    247  C4'  DG B   1     -81.254  41.002   3.742  1.00 45.36           C  
ANISOU  247  C4'  DG B   1     4534   7379   5320   1730   -499   1635       C  
ATOM    248  O4'  DG B   1     -81.686  40.448   5.009  1.00 41.01           O  
ANISOU  248  O4'  DG B   1     4004   6562   5015   1523   -498   1409       O  
ATOM    249  C3'  DG B   1     -79.732  40.878   3.748  1.00 43.36           C  
ANISOU  249  C3'  DG B   1     4435   7034   5006   1660   -390   1638       C  
ATOM    250  O3'  DG B   1     -79.167  42.056   4.336  1.00 45.08           O  
ANISOU  250  O3'  DG B   1     4713   6944   5468   1642   -161   1862       O  
ATOM    251  C2'  DG B   1     -79.515  39.620   4.561  1.00 40.62           C  
ANISOU  251  C2'  DG B   1     4152   6557   4724   1438   -472   1290       C  
ATOM    252  C1'  DG B   1     -80.634  39.701   5.602  1.00 40.17           C  
ANISOU  252  C1'  DG B   1     4036   6306   4920   1355   -461   1230       C  
ATOM    253  N9   DG B   1     -81.182  38.414   6.017  1.00 38.95           N  
ANISOU  253  N9   DG B   1     3819   6139   4839   1229   -579    953       N  
ATOM    254  C8   DG B   1     -81.567  37.369   5.210  1.00 41.09           C  
ANISOU  254  C8   DG B   1     3963   6634   5012   1242   -779    735       C  
ATOM    255  N7   DG B   1     -82.008  36.340   5.882  1.00 40.31           N  
ANISOU  255  N7   DG B   1     3795   6390   5129   1100   -809    526       N  
ATOM    256  C5   DG B   1     -81.916  36.732   7.210  1.00 37.10           C  
ANISOU  256  C5   DG B   1     3494   5700   4900   1018   -614    643       C  
ATOM    257  C6   DG B   1     -82.253  36.036   8.401  1.00 35.88           C  
ANISOU  257  C6   DG B   1     3322   5323   4985    904   -515    575       C  
ATOM    258  O6   DG B   1     -82.725  34.898   8.522  1.00 37.04           O  
ANISOU  258  O6   DG B   1     3335   5418   5317    825   -561    417       O  
ATOM    259  N1   DG B   1     -81.984  36.798   9.533  1.00 33.89           N  
ANISOU  259  N1   DG B   1     3205   4899   4772    907   -331    714       N  
ATOM    260  C2   DG B   1     -81.471  38.074   9.523  1.00 34.11           C  
ANISOU  260  C2   DG B   1     3343   4908   4708    977   -261    855       C  
ATOM    261  N2   DG B   1     -81.261  38.642  10.722  1.00 32.63           N  
ANISOU  261  N2   DG B   1     3251   4551   4595    977   -109    888       N  
ATOM    262  N3   DG B   1     -81.159  38.736   8.420  1.00 35.59           N  
ANISOU  262  N3   DG B   1     3528   5237   4757   1063   -322    953       N  
ATOM    263  C4   DG B   1     -81.399  38.007   7.309  1.00 36.58           C  
ANISOU  263  C4   DG B   1     3549   5589   4757   1092   -493    861       C  
ATOM    264  P    DC B   2     -77.555  42.239   4.471  1.00 49.61           P  
ANISOU  264  P    DC B   2     5404   7344   6101   1566    -10   1902       P  
ATOM    265  OP1  DC B   2     -77.236  43.605   4.047  1.00 49.83           O  
ANISOU  265  OP1  DC B   2     5373   7263   6296   1711    199   2272       O  
ATOM    266  OP2  DC B   2     -76.855  41.032   3.907  1.00 49.04           O  
ANISOU  266  OP2  DC B   2     5388   7493   5749   1535   -130   1717       O  
ATOM    267  O5'  DC B   2     -77.283  42.071   6.039  1.00 44.48           O  
ANISOU  267  O5'  DC B   2     4844   6350   5704   1342     24   1651       O  
ATOM    268  C5'  DC B   2     -77.992  42.892   6.984  1.00 45.57           C  
ANISOU  268  C5'  DC B   2     4951   6252   6110   1324    104   1661       C  
ATOM    269  C4'  DC B   2     -77.580  42.551   8.396  1.00 43.45           C  
ANISOU  269  C4'  DC B   2     4776   5772   5961   1164    117   1393       C  
ATOM    270  O4'  DC B   2     -78.143  41.282   8.788  1.00 42.58           O  
ANISOU  270  O4'  DC B   2     4687   5780   5710   1092     -6   1202       O  
ATOM    271  C3'  DC B   2     -76.075  42.443   8.637  1.00 42.66           C  
ANISOU  271  C3'  DC B   2     4755   5565   5887   1076    159   1299       C  
ATOM    272  O3'  DC B   2     -75.786  43.153   9.849  1.00 43.74           O  
ANISOU  272  O3'  DC B   2     4904   5443   6270   1026    237   1157       O  
ATOM    273  C2'  DC B   2     -75.824  40.945   8.694  1.00 39.88           C  
ANISOU  273  C2'  DC B   2     4476   5375   5302    991     31   1114       C  
ATOM    274  C1'  DC B   2     -77.126  40.403   9.255  1.00 38.79           C  
ANISOU  274  C1'  DC B   2     4305   5278   5152    983    -31   1026       C  
ATOM    275  N1   DC B   2     -77.520  39.043   8.843  1.00 36.40           N  
ANISOU  275  N1   DC B   2     3978   5150   4701    947   -158    920       N  
ATOM    276  C2   DC B   2     -77.921  38.126   9.821  1.00 33.76           C  
ANISOU  276  C2   DC B   2     3649   4756   4421    874   -163    778       C  
ATOM    277  O2   DC B   2     -77.848  38.454  11.017  1.00 34.33           O  
ANISOU  277  O2   DC B   2     3775   4692   4577    866    -69    748       O  
ATOM    278  N3   DC B   2     -78.331  36.894   9.443  1.00 32.17           N  
ANISOU  278  N3   DC B   2     3378   4650   4194    832   -259    673       N  
ATOM    279  C4   DC B   2     -78.421  36.592   8.145  1.00 35.10           C  
ANISOU  279  C4   DC B   2     3678   5212   4446    872   -385    645       C  
ATOM    280  N4   DC B   2     -78.867  35.378   7.813  1.00 35.87           N  
ANISOU  280  N4   DC B   2     3672   5376   4581    826   -495    469       N  
ATOM    281  C5   DC B   2     -78.023  37.509   7.129  1.00 36.06           C  
ANISOU  281  C5   DC B   2     3813   5470   4417    982   -393    794       C  
ATOM    282  C6   DC B   2     -77.598  38.716   7.519  1.00 36.47           C  
ANISOU  282  C6   DC B   2     3928   5383   4545   1013   -258    960       C  
ATOM    283  P    DC B   3     -74.265  43.434  10.296  1.00 49.84           P  
ANISOU  283  P    DC B   3     5700   6041   7193    946    283   1022       P  
ATOM    284  OP1  DC B   3     -74.247  44.709  11.068  1.00 49.62           O  
ANISOU  284  OP1  DC B   3     5596   5735   7523    960    381    934       O  
ATOM    285  OP2  DC B   3     -73.352  43.227   9.127  1.00 43.90           O  
ANISOU  285  OP2  DC B   3     4938   5376   6365    955    310   1198       O  
ATOM    286  O5'  DC B   3     -74.000  42.244  11.328  1.00 40.88           O  
ANISOU  286  O5'  DC B   3     4671   5002   5857    867    173    750       O  
ATOM    287  C5'  DC B   3     -74.760  42.239  12.532  1.00 37.87           C  
ANISOU  287  C5'  DC B   3     4310   4601   5476    893    165    592       C  
ATOM    288  C4'  DC B   3     -74.449  41.004  13.329  1.00 33.61           C  
ANISOU  288  C4'  DC B   3     3857   4192   4721    862     97    437       C  
ATOM    289  O4'  DC B   3     -74.932  39.834  12.636  1.00 31.05           O  
ANISOU  289  O4'  DC B   3     3545   4020   4232    834     47    543       O  
ATOM    290  C3'  DC B   3     -72.960  40.777  13.569  1.00 31.85           C  
ANISOU  290  C3'  DC B   3     3667   3953   4481    809     58    300       C  
ATOM    291  O3'  DC B   3     -72.816  40.619  14.981  1.00 33.41           O  
ANISOU  291  O3'  DC B   3     3899   4193   4602    864     36     86       O  
ATOM    292  C2'  DC B   3     -72.644  39.538  12.749  1.00 29.41           C  
ANISOU  292  C2'  DC B   3     3400   3782   3992    755     10    394       C  
ATOM    293  C1'  DC B   3     -73.966  38.813  12.712  1.00 29.42           C  
ANISOU  293  C1'  DC B   3     3395   3880   3900    779      1    466       C  
ATOM    294  N1   DC B   3     -74.197  37.928  11.565  1.00 29.14           N  
ANISOU  294  N1   DC B   3     3340   3960   3772    746    -54    548       N  
ATOM    295  C2   DC B   3     -74.769  36.670  11.780  1.00 29.35           C  
ANISOU  295  C2   DC B   3     3352   4049   3751    724    -81    510       C  
ATOM    296  O2   DC B   3     -74.947  36.282  12.942  1.00 29.16           O  
ANISOU  296  O2   DC B   3     3348   3995   3736    747    -28    471       O  
ATOM    297  N3   DC B   3     -75.067  35.891  10.717  1.00 30.47           N  
ANISOU  297  N3   DC B   3     3438   4287   3852    698   -157    509       N  
ATOM    298  C4   DC B   3     -74.856  36.344   9.479  1.00 29.49           C  
ANISOU  298  C4   DC B   3     3293   4260   3650    729   -206    568       C  
ATOM    299  N4   DC B   3     -75.166  35.545   8.462  1.00 29.40           N  
ANISOU  299  N4   DC B   3     3216   4397   3556    736   -305    507       N  
ATOM    300  C5   DC B   3     -74.285  37.627   9.231  1.00 30.71           C  
ANISOU  300  C5   DC B   3     3470   4367   3827    774   -142    689       C  
ATOM    301  C6   DC B   3     -73.993  38.385  10.292  1.00 30.06           C  
ANISOU  301  C6   DC B   3     3422   4124   3873    764    -67    665       C  
ATOM    302  P    DA B   4     -71.383  40.646  15.667  1.00 33.85           P  
ANISOU  302  P    DA B   4     3952   4249   4658    858    -29   -143       P  
ATOM    303  OP1  DA B   4     -71.596  41.076  17.072  1.00 35.36           O  
ANISOU  303  OP1  DA B   4     4137   4493   4803    981    -48   -388       O  
ATOM    304  OP2  DA B   4     -70.436  41.393  14.803  1.00 34.05           O  
ANISOU  304  OP2  DA B   4     3899   4100   4935    772    -16   -120       O  
ATOM    305  O5'  DA B   4     -70.989  39.114  15.675  1.00 29.15           O  
ANISOU  305  O5'  DA B   4     3434   3829   3812    843    -66    -77       O  
ATOM    306  C5'  DA B   4     -71.785  38.181  16.413  1.00 28.74           C  
ANISOU  306  C5'  DA B   4     3430   3920   3570    927    -34    -23       C  
ATOM    307  C4'  DA B   4     -71.386  36.775  16.056  1.00 27.90           C  
ANISOU  307  C4'  DA B   4     3357   3891   3353    883    -40     83       C  
ATOM    308  O4'  DA B   4     -71.794  36.483  14.688  1.00 25.89           O  
ANISOU  308  O4'  DA B   4     3081   3581   3172    779    -41    219       O  
ATOM    309  C3'  DA B   4     -69.874  36.526  16.109  1.00 28.24           C  
ANISOU  309  C3'  DA B   4     3408   3961   3358    857   -107    -18       C  
ATOM    310  O3'  DA B   4     -69.659  35.184  16.548  1.00 29.63           O  
ANISOU  310  O3'  DA B   4     3613   4250   3393    906    -84     53       O  
ATOM    311  C2'  DA B   4     -69.473  36.634  14.652  1.00 25.47           C  
ANISOU  311  C2'  DA B   4     3039   3515   3124    729   -117     64       C  
ATOM    312  C1'  DA B   4     -70.657  35.941  14.034  1.00 26.02           C  
ANISOU  312  C1'  DA B   4     3111   3607   3165    711    -82    209       C  
ATOM    313  N9   DA B   4     -70.832  36.063  12.578  1.00 24.29           N  
ANISOU  313  N9   DA B   4     2866   3374   2987    649    -95    302       N  
ATOM    314  C8   DA B   4     -70.373  37.016  11.710  1.00 25.00           C  
ANISOU  314  C8   DA B   4     2928   3415   3154    633    -84    357       C  
ATOM    315  N7   DA B   4     -70.672  36.775  10.450  1.00 26.09           N  
ANISOU  315  N7   DA B   4     3046   3634   3232    634    -94    461       N  
ATOM    316  C5   DA B   4     -71.353  35.568  10.495  1.00 24.67           C  
ANISOU  316  C5   DA B   4     2867   3530   2975    621   -139    412       C  
ATOM    317  C6   DA B   4     -71.890  34.744   9.492  1.00 25.94           C  
ANISOU  317  C6   DA B   4     2984   3803   3067    620   -199    398       C  
ATOM    318  N6   DA B   4     -71.866  35.045   8.189  1.00 27.86           N  
ANISOU  318  N6   DA B   4     3197   4175   3210    671   -231    456       N  
ATOM    319  N1   DA B   4     -72.480  33.589   9.876  1.00 25.17           N  
ANISOU  319  N1   DA B   4     2850   3690   3020    588   -219    315       N  
ATOM    320  C2   DA B   4     -72.498  33.280  11.181  1.00 26.68           C  
ANISOU  320  C2   DA B   4     3066   3790   3279    586   -152    319       C  
ATOM    321  N3   DA B   4     -72.015  33.966  12.216  1.00 24.95           N  
ANISOU  321  N3   DA B   4     2907   3531   3040    622   -103    337       N  
ATOM    322  C4   DA B   4     -71.419  35.096  11.799  1.00 25.06           C  
ANISOU  322  C4   DA B   4     2942   3534   3043    623   -116    347       C  
ATOM    323  P    DC B   5     -68.863  34.856  17.902  1.00 29.42           P  
ANISOU  323  P    DC B   5     3596   4397   3183   1064   -111    -43       P  
ATOM    324  OP1  DC B   5     -69.303  35.797  18.933  1.00 31.96           O  
ANISOU  324  OP1  DC B   5     3909   4804   3430   1202   -124   -192       O  
ATOM    325  OP2  DC B   5     -67.424  34.759  17.582  1.00 28.70           O  
ANISOU  325  OP2  DC B   5     3485   4301   3119   1004   -199   -139       O  
ATOM    326  O5'  DC B   5     -69.356  33.371  18.193  1.00 30.61           O  
ANISOU  326  O5'  DC B   5     3758   4612   3258   1133      5    182       O  
ATOM    327  C5'  DC B   5     -70.747  33.108  18.465  1.00 29.72           C  
ANISOU  327  C5'  DC B   5     3629   4484   3177   1188    129    335       C  
ATOM    328  C4'  DC B   5     -71.067  31.668  18.152  1.00 29.87           C  
ANISOU  328  C4'  DC B   5     3605   4431   3314   1156    240    538       C  
ATOM    329  O4'  DC B   5     -71.252  31.509  16.721  1.00 27.19           O  
ANISOU  329  O4'  DC B   5     3236   3932   3160    957    181    502       O  
ATOM    330  C3'  DC B   5     -70.002  30.648  18.556  1.00 30.24           C  
ANISOU  330  C3'  DC B   5     3650   4548   3289   1231    267    610       C  
ATOM    331  O3'  DC B   5     -70.675  29.478  18.996  1.00 32.21           O  
ANISOU  331  O3'  DC B   5     3830   4757   3648   1319    455    860       O  
ATOM    332  C2'  DC B   5     -69.219  30.412  17.271  1.00 28.18           C  
ANISOU  332  C2'  DC B   5     3391   4162   3152   1040    169    512       C  
ATOM    333  C1'  DC B   5     -70.271  30.608  16.188  1.00 27.06           C  
ANISOU  333  C1'  DC B   5     3215   3881   3182    894    157    493       C  
ATOM    334  N1   DC B   5     -69.792  31.188  14.922  1.00 25.76           N  
ANISOU  334  N1   DC B   5     3072   3675   3039    757     39    363       N  
ATOM    335  C2   DC B   5     -70.222  30.637  13.704  1.00 26.32           C  
ANISOU  335  C2   DC B   5     3092   3673   3233    652     16    339       C  
ATOM    336  O2   DC B   5     -70.944  29.615  13.720  1.00 26.91           O  
ANISOU  336  O2   DC B   5     3086   3673   3466    644     82    387       O  
ATOM    337  N3   DC B   5     -69.809  31.204  12.544  1.00 24.35           N  
ANISOU  337  N3   DC B   5     2860   3447   2943    583    -69    261       N  
ATOM    338  C4   DC B   5     -69.057  32.309  12.572  1.00 24.23           C  
ANISOU  338  C4   DC B   5     2893   3460   2853    591   -102    239       C  
ATOM    339  N4   DC B   5     -68.690  32.847  11.410  1.00 23.47           N  
ANISOU  339  N4   DC B   5     2794   3381   2740    551   -137    232       N  
ATOM    340  C5   DC B   5     -68.626  32.898  13.797  1.00 25.12           C  
ANISOU  340  C5   DC B   5     3033   3591   2919    660    -94    215       C  
ATOM    341  C6   DC B   5     -69.023  32.318  14.935  1.00 25.29           C  
ANISOU  341  C6   DC B   5     3054   3654   2898    754    -38    262       C  
ATOM    342  P    DC B   6     -69.876  28.298  19.688  1.00 36.75           P  
ANISOU  342  P    DC B   6     4375   5406   4180   1473    567   1051       P  
ATOM    343  OP1  DC B   6     -70.858  27.547  20.539  1.00 38.44           O  
ANISOU  343  OP1  DC B   6     4504   5617   4481   1648    818   1364       O  
ATOM    344  OP2  DC B   6     -68.610  28.822  20.242  1.00 36.03           O  
ANISOU  344  OP2  DC B   6     4349   5540   3799   1584    428    910       O  
ATOM    345  O5'  DC B   6     -69.421  27.396  18.476  1.00 33.33           O  
ANISOU  345  O5'  DC B   6     3895   4748   4018   1271    542   1011       O  
ATOM    346  C5'  DC B   6     -70.399  26.808  17.638  1.00 34.38           C  
ANISOU  346  C5'  DC B   6     3931   4648   4482   1122    604   1027       C  
ATOM    347  C4'  DC B   6     -69.689  26.274  16.430  1.00 36.59           C  
ANISOU  347  C4'  DC B   6     4196   4801   4906    954    508    865       C  
ATOM    348  O4'  DC B   6     -69.207  27.359  15.593  1.00 33.18           O  
ANISOU  348  O4'  DC B   6     3858   4448   4299    844    314    640       O  
ATOM    349  C3'  DC B   6     -68.461  25.422  16.790  1.00 37.26           C  
ANISOU  349  C3'  DC B   6     4278   4905   4972   1039    563    955       C  
ATOM    350  O3'  DC B   6     -68.770  24.160  16.225  1.00 41.20           O  
ANISOU  350  O3'  DC B   6     4643   5158   5851    961    672    986       O  
ATOM    351  C2'  DC B   6     -67.280  26.216  16.236  1.00 37.93           C  
ANISOU  351  C2'  DC B   6     4466   5106   4837    970    373    746       C  
ATOM    352  C1'  DC B   6     -67.932  26.999  15.102  1.00 35.28           C  
ANISOU  352  C1'  DC B   6     4150   4719   4533    806    257    560       C  
ATOM    353  N1   DC B   6     -67.258  28.233  14.599  1.00 33.40           N  
ANISOU  353  N1   DC B   6     3997   4581   4112    750    110    409       N  
ATOM    354  C2   DC B   6     -67.320  28.504  13.231  1.00 32.31           C  
ANISOU  354  C2   DC B   6     3858   4405   4011    627     32    283       C  
ATOM    355  O2   DC B   6     -67.926  27.716  12.488  1.00 31.96           O  
ANISOU  355  O2   DC B   6     3746   4277   4118    569     46    236       O  
ATOM    356  N3   DC B   6     -66.711  29.609  12.746  1.00 31.57           N  
ANISOU  356  N3   DC B   6     3814   4374   3806    594    -48    214       N  
ATOM    357  C4   DC B   6     -66.083  30.441  13.570  1.00 30.73           C  
ANISOU  357  C4   DC B   6     3737   4326   3613    647    -76    206       C  
ATOM    358  N4   DC B   6     -65.531  31.536  13.045  1.00 31.33           N  
ANISOU  358  N4   DC B   6     3818   4401   3683    603   -129    145       N  
ATOM    359  C5   DC B   6     -66.007  30.198  14.976  1.00 33.82           C  
ANISOU  359  C5   DC B   6     4129   4789   3932    773    -46    257       C  
ATOM    360  C6   DC B   6     -66.594  29.085  15.441  1.00 33.27           C  
ANISOU  360  C6   DC B   6     4029   4695   3915    836     58    388       C  
ATOM    361  P    DG B   7     -67.922  22.814  16.619  1.00 39.46           P  
ANISOU  361  P    DG B   7     4342   4834   5817   1061    834   1171       P  
ATOM    362  OP1  DG B   7     -68.823  21.935  17.363  1.00 44.04           O  
ANISOU  362  OP1  DG B   7     4769   5253   6711   1169   1093   1466       O  
ATOM    363  OP2  DG B   7     -66.618  23.216  17.179  1.00 41.13           O  
ANISOU  363  OP2  DG B   7     4663   5282   5682   1184    757   1200       O  
ATOM    364  O5'  DG B   7     -67.719  22.155  15.195  1.00 37.38           O  
ANISOU  364  O5'  DG B   7     4007   4358   5834    863    758    902       O  
ATOM    365  C5'  DG B   7     -68.852  21.848  14.367  1.00 37.35           C  
ANISOU  365  C5'  DG B   7     3876   4160   6152    721    742    731       C  
ATOM    366  C4'  DG B   7     -68.354  21.554  12.979  1.00 37.01           C  
ANISOU  366  C4'  DG B   7     3819   4068   6173    584    595    394       C  
ATOM    367  O4'  DG B   7     -67.784  22.774  12.439  1.00 33.80           O  
ANISOU  367  O4'  DG B   7     3587   3916   5336    556    404    259       O  
ATOM    368  C3'  DG B   7     -67.233  20.506  12.953  1.00 35.86           C  
ANISOU  368  C3'  DG B   7     3631   3804   6187    622    688    419       C  
ATOM    369  O3'  DG B   7     -67.412  19.614  11.852  1.00 38.46           O  
ANISOU  369  O3'  DG B   7     3814   3931   6865    511    658    117       O  
ATOM    370  C2'  DG B   7     -65.965  21.339  12.873  1.00 34.33           C  
ANISOU  370  C2'  DG B   7     3622   3866   5554    657    564    396       C  
ATOM    371  C1'  DG B   7     -66.406  22.590  12.137  1.00 33.57           C  
ANISOU  371  C1'  DG B   7     3625   3946   5184    572    376    211       C  
ATOM    372  N9   DG B   7     -65.714  23.820  12.512  1.00 31.92           N  
ANISOU  372  N9   DG B   7     3567   3960   4601    617    290    276       N  
ATOM    373  C8   DG B   7     -65.407  24.251  13.781  1.00 30.60           C  
ANISOU  373  C8   DG B   7     3452   3902   4271    738    332    475       C  
ATOM    374  N7   DG B   7     -64.836  25.424  13.798  1.00 29.99           N  
ANISOU  374  N7   DG B   7     3471   3988   3935    737    214    415       N  
ATOM    375  C5   DG B   7     -64.806  25.811  12.464  1.00 28.85           C  
ANISOU  375  C5   DG B   7     3346   3840   3776    619    123    234       C  
ATOM    376  C6   DG B   7     -64.313  26.995  11.864  1.00 27.30           C  
ANISOU  376  C6   DG B   7     3213   3749   3408    578     26    154       C  
ATOM    377  O6   DG B   7     -63.781  27.969  12.409  1.00 28.96           O  
ANISOU  377  O6   DG B   7     3462   4038   3502    607    -17    178       O  
ATOM    378  N1   DG B   7     -64.439  26.960  10.482  1.00 27.38           N  
ANISOU  378  N1   DG B   7     3215   3770   3418    516    -11     29       N  
ATOM    379  C2   DG B   7     -65.018  25.941   9.769  1.00 29.44           C  
ANISOU  379  C2   DG B   7     3405   3962   3817    487     -2    -89       C  
ATOM    380  N2   DG B   7     -65.070  26.101   8.438  1.00 29.87           N  
ANISOU  380  N2   DG B   7     3455   4116   3778    474    -67   -239       N  
ATOM    381  N3   DG B   7     -65.490  24.831  10.318  1.00 30.99           N  
ANISOU  381  N3   DG B   7     3518   4006   4250    491     75    -68       N  
ATOM    382  C4   DG B   7     -65.365  24.842  11.660  1.00 29.39           C  
ANISOU  382  C4   DG B   7     3332   3780   4054    560    153    133       C  
ATOM    383  P    DG B   8     -66.475  18.370  11.666  1.00 41.45           P  
ANISOU  383  P    DG B   8     4098   4108   7543    533    774     83       P  
ATOM    384  OP1  DG B   8     -67.269  17.291  11.057  1.00 43.61           O  
ANISOU  384  OP1  DG B   8     4123   4058   8387    441    824   -160       O  
ATOM    385  OP2  DG B   8     -65.742  18.133  12.948  1.00 40.60           O  
ANISOU  385  OP2  DG B   8     4028   4015   7380    695    957    499       O  
ATOM    386  O5'  DG B   8     -65.378  18.889  10.622  1.00 38.84           O  
ANISOU  386  O5'  DG B   8     3915   4005   6834    502    588   -176       O  
ATOM    387  C5'  DG B   8     -65.748  19.437   9.337  1.00 39.78           C  
ANISOU  387  C5'  DG B   8     4063   4278   6772    420    385   -531       C  
ATOM    388  C4'  DG B   8     -64.589  20.206   8.744  1.00 38.12           C  
ANISOU  388  C4'  DG B   8     4024   4332   6128    451    284   -579       C  
ATOM    389  O4'  DG B   8     -64.307  21.377   9.536  1.00 36.24           O  
ANISOU  389  O4'  DG B   8     3935   4269   5562    489    267   -315       O  
ATOM    390  C3'  DG B   8     -63.272  19.429   8.664  1.00 39.98           C  
ANISOU  390  C3'  DG B   8     4251   4496   6444    498    374   -578       C  
ATOM    391  O3'  DG B   8     -62.965  19.159   7.298  1.00 44.69           O  
ANISOU  391  O3'  DG B   8     4823   5167   6989    487    288   -929       O  
ATOM    392  C2'  DG B   8     -62.245  20.340   9.326  1.00 37.54           C  
ANISOU  392  C2'  DG B   8     4093   4374   5795    558    372   -320       C  
ATOM    393  C1'  DG B   8     -62.929  21.678   9.396  1.00 34.00           C  
ANISOU  393  C1'  DG B   8     3744   4109   5066    530    259   -276       C  
ATOM    394  N9   DG B   8     -62.538  22.508  10.531  1.00 31.50           N  
ANISOU  394  N9   DG B   8     3512   3894   4560    585    266    -25       N  
ATOM    395  C8   DG B   8     -62.642  22.186  11.862  1.00 32.69           C  
ANISOU  395  C8   DG B   8     3636   3991   4792    670    363    212       C  
ATOM    396  N7   DG B   8     -62.265  23.153  12.653  1.00 32.54           N  
ANISOU  396  N7   DG B   8     3696   4141   4524    730    308    328       N  
ATOM    397  C5   DG B   8     -61.900  24.178  11.794  1.00 31.22           C  
ANISOU  397  C5   DG B   8     3599   4087   4175    655    190    181       C  
ATOM    398  C6   DG B   8     -61.401  25.485  12.072  1.00 30.81           C  
ANISOU  398  C6   DG B   8     3609   4178   3920    661    100    190       C  
ATOM    399  O6   DG B   8     -61.197  26.016  13.169  1.00 30.90           O  
ANISOU  399  O6   DG B   8     3630   4278   3832    736     68    268       O  
ATOM    400  N1   DG B   8     -61.172  26.202  10.907  1.00 29.63           N  
ANISOU  400  N1   DG B   8     3486   4071   3698    588     50     81       N  
ATOM    401  C2   DG B   8     -61.391  25.731   9.635  1.00 28.45           C  
ANISOU  401  C2   DG B   8     3325   3906   3576    549     62    -38       C  
ATOM    402  N2   DG B   8     -61.106  26.571   8.639  1.00 29.33           N  
ANISOU  402  N2   DG B   8     3463   4119   3560    536     37    -74       N  
ATOM    403  N3   DG B   8     -61.846  24.519   9.362  1.00 30.40           N  
ANISOU  403  N3   DG B   8     3516   4051   3984    544    105   -123       N  
ATOM    404  C4   DG B   8     -62.065  23.798  10.481  1.00 31.64           C  
ANISOU  404  C4   DG B   8     3630   4093   4299    582    176      0       C  
ATOM    405  P    DT B   9     -61.686  18.345   6.915  1.00 47.88           P  
ANISOU  405  P    DT B   9     5203   5508   7479    538    371  -1014       P  
ATOM    406  OP1  DT B   9     -62.004  17.564   5.710  1.00 48.99           O  
ANISOU  406  OP1  DT B   9     5220   5605   7788    530    311  -1458       O  
ATOM    407  OP2  DT B   9     -61.145  17.663   8.144  1.00 43.99           O  
ANISOU  407  OP2  DT B   9     4663   4799   7250    581    548   -700       O  
ATOM    408  O5'  DT B   9     -60.625  19.493   6.579  1.00 44.65           O  
ANISOU  408  O5'  DT B   9     4964   5400   6597    585    316   -905       O  
ATOM    409  C5'  DT B   9     -60.905  20.602   5.706  1.00 41.46           C  
ANISOU  409  C5'  DT B   9     4651   5274   5827    593    192   -992       C  
ATOM    410  C4'  DT B   9     -59.714  21.538   5.696  1.00 38.96           C  
ANISOU  410  C4'  DT B   9     4443   5127   5232    636    219   -793       C  
ATOM    411  O4'  DT B   9     -59.720  22.315   6.922  1.00 36.15           O  
ANISOU  411  O4'  DT B   9     4140   4746   4849    605    219   -513       O  
ATOM    412  C3'  DT B   9     -58.343  20.834   5.660  1.00 39.37           C  
ANISOU  412  C3'  DT B   9     4465   5114   5377    686    326   -778       C  
ATOM    413  O3'  DT B   9     -57.358  21.568   4.924  1.00 37.89           O  
ANISOU  413  O3'  DT B   9     4333   5126   4938    743    349   -735       O  
ATOM    414  C2'  DT B   9     -57.909  20.866   7.109  1.00 38.02           C  
ANISOU  414  C2'  DT B   9     4294   4823   5325    675    375   -494       C  
ATOM    415  C1'  DT B   9     -58.424  22.236   7.496  1.00 35.47           C  
ANISOU  415  C1'  DT B   9     4054   4634   4787    639    286   -361       C  
ATOM    416  N1   DT B   9     -58.518  22.561   8.953  1.00 34.72           N  
ANISOU  416  N1   DT B   9     3970   4500   4722    646    278   -142       N  
ATOM    417  C2   DT B   9     -58.192  23.845   9.334  1.00 32.76           C  
ANISOU  417  C2   DT B   9     3772   4376   4298    639    212    -44       C  
ATOM    418  O2   DT B   9     -57.859  24.712   8.544  1.00 32.81           O  
ANISOU  418  O2   DT B   9     3805   4481   4179    618    190    -77       O  
ATOM    419  N3   DT B   9     -58.275  24.081  10.682  1.00 31.18           N  
ANISOU  419  N3   DT B   9     3568   4184   4091    680    186     95       N  
ATOM    420  C4   DT B   9     -58.625  23.180  11.670  1.00 32.67           C  
ANISOU  420  C4   DT B   9     3718   4298   4396    754    249    215       C  
ATOM    421  O4   DT B   9     -58.675  23.550  12.843  1.00 32.21           O  
ANISOU  421  O4   DT B   9     3664   4326   4248    835    220    342       O  
ATOM    422  C5   DT B   9     -58.953  21.848  11.203  1.00 34.85           C  
ANISOU  422  C5   DT B   9     3930   4396   4914    748    356    169       C  
ATOM    423  C7   DT B   9     -59.332  20.798  12.201  1.00 38.36           C  
ANISOU  423  C7   DT B   9     4294   4704   5576    840    485    358       C  
ATOM    424  C6   DT B   9     -58.884  21.608   9.886  1.00 35.73           C  
ANISOU  424  C6   DT B   9     4036   4478   5062    683    350    -41       C  
ATOM    425  P    DG B  10     -56.969  21.140   3.432  1.00 43.02           P  
ANISOU  425  P    DG B  10     4962   5935   5449    847    381   -991       P  
ATOM    426  OP1  DG B  10     -58.214  20.939   2.672  1.00 42.89           O  
ANISOU  426  OP1  DG B  10     4920   6014   5362    866    270  -1272       O  
ATOM    427  OP2  DG B  10     -55.981  20.035   3.522  1.00 41.43           O  
ANISOU  427  OP2  DG B  10     4692   5580   5469    880    489  -1053       O  
ATOM    428  O5'  DG B  10     -56.239  22.455   2.910  1.00 40.83           O  
ANISOU  428  O5'  DG B  10     4749   5888   4875    910    427   -781       O  
ATOM    429  C5'  DG B  10     -56.970  23.683   2.773  1.00 39.98           C  
ANISOU  429  C5'  DG B  10     4696   5921   4571    903    366   -654       C  
ATOM    430  C4'  DG B  10     -56.060  24.873   2.995  1.00 40.35           C  
ANISOU  430  C4'  DG B  10     4753   5996   4580    901    449   -357       C  
ATOM    431  O4'  DG B  10     -55.797  25.072   4.407  1.00 36.09           O  
ANISOU  431  O4'  DG B  10     4199   5258   4253    787    414   -225       O  
ATOM    432  C3'  DG B  10     -54.688  24.806   2.337  1.00 41.63           C  
ANISOU  432  C3'  DG B  10     4874   6230   4713    994    601   -289       C  
ATOM    433  O3'  DG B  10     -54.339  26.146   1.975  1.00 44.61           O  
ANISOU  433  O3'  DG B  10     5238   6704   5006   1034    691    -33       O  
ATOM    434  C2'  DG B  10     -53.804  24.211   3.426  1.00 38.99           C  
ANISOU  434  C2'  DG B  10     4487   5676   4651    914    612   -250       C  
ATOM    435  C1'  DG B  10     -54.422  24.761   4.709  1.00 35.97           C  
ANISOU  435  C1'  DG B  10     4122   5170   4374    798    495   -155       C  
ATOM    436  N9   DG B  10     -54.456  23.892   5.873  1.00 34.15           N  
ANISOU  436  N9   DG B  10     3869   4777   4327    753    444   -179       N  
ATOM    437  C8   DG B  10     -54.758  22.552   5.902  1.00 36.47           C  
ANISOU  437  C8   DG B  10     4143   4967   4744    771    462   -318       C  
ATOM    438  N7   DG B  10     -54.894  22.086   7.116  1.00 35.06           N  
ANISOU  438  N7   DG B  10     3939   4657   4725    752    439   -230       N  
ATOM    439  C5   DG B  10     -54.753  23.201   7.929  1.00 32.26           C  
ANISOU  439  C5   DG B  10     3600   4363   4294    725    368    -78       C  
ATOM    440  C6   DG B  10     -54.795  23.316   9.340  1.00 31.22           C  
ANISOU  440  C6   DG B  10     3450   4209   4203    741    308     46       C  
ATOM    441  O6   DG B  10     -54.976  22.431  10.173  1.00 32.36           O  
ANISOU  441  O6   DG B  10     3563   4278   4452    797    336    119       O  
ATOM    442  N1   DG B  10     -54.526  24.614   9.756  1.00 30.14           N  
ANISOU  442  N1   DG B  10     3309   4158   3982    715    224     93       N  
ATOM    443  C2   DG B  10     -54.306  25.682   8.918  1.00 29.90           C  
ANISOU  443  C2   DG B  10     3282   4175   3903    666    232     76       C  
ATOM    444  N2   DG B  10     -54.091  26.862   9.508  1.00 29.98           N  
ANISOU  444  N2   DG B  10     3251   4206   3934    636    157    104       N  
ATOM    445  N3   DG B  10     -54.288  25.593   7.597  1.00 30.67           N  
ANISOU  445  N3   DG B  10     3402   4306   3944    671    320     36       N  
ATOM    446  C4   DG B  10     -54.500  24.327   7.176  1.00 31.91           C  
ANISOU  446  C4   DG B  10     3574   4429   4120    707    368    -63       C  
ATOM    447  P    DG B  11     -52.997  26.456   1.167  1.00 51.19           P  
ANISOU  447  P    DG B  11     6001   7631   5815   1154    900    138       P  
ATOM    448  OP1  DG B  11     -53.213  27.729   0.408  1.00 53.47           O  
ANISOU  448  OP1  DG B  11     6279   8078   5957   1255   1011    388       O  
ATOM    449  OP2  DG B  11     -52.573  25.225   0.465  1.00 50.20           O  
ANISOU  449  OP2  DG B  11     5876   7603   5593   1266    953    -75       O  
ATOM    450  O5'  DG B  11     -51.936  26.750   2.312  1.00 45.69           O  
ANISOU  450  O5'  DG B  11     5209   6689   5460   1022    912    269       O  
ATOM    451  C5'  DG B  11     -52.072  27.909   3.145  1.00 43.57           C  
ANISOU  451  C5'  DG B  11     4897   6288   5366    910    855    411       C  
ATOM    452  C4'  DG B  11     -51.046  27.867   4.250  1.00 40.89           C  
ANISOU  452  C4'  DG B  11     4447   5770   5319    816    810    416       C  
ATOM    453  O4'  DG B  11     -51.420  26.860   5.217  1.00 39.17           O  
ANISOU  453  O4'  DG B  11     4284   5494   5103    769    658    252       O  
ATOM    454  C3'  DG B  11     -49.616  27.530   3.804  1.00 43.44           C  
ANISOU  454  C3'  DG B  11     4652   6086   5767    877    965    486       C  
ATOM    455  O3'  DG B  11     -48.772  28.587   4.267  1.00 45.19           O  
ANISOU  455  O3'  DG B  11     4701   6173   6296    810    997    619       O  
ATOM    456  C2'  DG B  11     -49.337  26.175   4.442  1.00 40.65           C  
ANISOU  456  C2'  DG B  11     4315   5686   5443    872    879    323       C  
ATOM    457  C1'  DG B  11     -50.244  26.203   5.648  1.00 37.61           C  
ANISOU  457  C1'  DG B  11     3989   5233   5066    782    680    244       C  
ATOM    458  N9   DG B  11     -50.636  24.913   6.206  1.00 33.72           N  
ANISOU  458  N9   DG B  11     3554   4704   4553    797    610    126       N  
ATOM    459  C8   DG B  11     -50.908  23.745   5.531  1.00 34.54           C  
ANISOU  459  C8   DG B  11     3711   4819   4594    857    673      3       C  
ATOM    460  N7   DG B  11     -51.250  22.763   6.324  1.00 33.39           N  
ANISOU  460  N7   DG B  11     3571   4571   4545    853    620    -50       N  
ATOM    461  C5   DG B  11     -51.223  23.322   7.593  1.00 31.55           C  
ANISOU  461  C5   DG B  11     3309   4316   4362    815    509     57       C  
ATOM    462  C6   DG B  11     -51.501  22.742   8.857  1.00 31.45           C  
ANISOU  462  C6   DG B  11     3283   4251   4415    842    439    109       C  
ATOM    463  O6   DG B  11     -51.850  21.580   9.112  1.00 33.25           O  
ANISOU  463  O6   DG B  11     3510   4384   4737    888    489    107       O  
ATOM    464  N1   DG B  11     -51.331  23.658   9.888  1.00 29.41           N  
ANISOU  464  N1   DG B  11     2986   4061   4125    835    316    173       N  
ATOM    465  C2   DG B  11     -50.947  24.970   9.726  1.00 29.97           C  
ANISOU  465  C2   DG B  11     3014   4178   4196    776    266    160       C  
ATOM    466  N2   DG B  11     -50.839  25.699  10.843  1.00 30.13           N  
ANISOU  466  N2   DG B  11     2973   4253   4222    782    123    148       N  
ATOM    467  N3   DG B  11     -50.692  25.525   8.553  1.00 30.46           N  
ANISOU  467  N3   DG B  11     3071   4234   4267    735    363    160       N  
ATOM    468  C4   DG B  11     -50.845  24.649   7.537  1.00 31.97           C  
ANISOU  468  C4   DG B  11     3322   4423   4401    772    482    123       C  
ATOM    469  P    DC B  12     -47.262  28.697   3.836  1.00 49.12           P  
ANISOU  469  P    DC B  12     5008   6620   7035    853   1183    755       P  
ATOM    470  OP1  DC B  12     -46.936  30.134   3.691  1.00 51.64           O  
ANISOU  470  OP1  DC B  12     5160   6815   7645    813   1298    949       O  
ATOM    471  OP2  DC B  12     -46.996  27.761   2.705  1.00 46.93           O  
ANISOU  471  OP2  DC B  12     4799   6503   6527   1005   1352    767       O  
ATOM    472  O5'  DC B  12     -46.508  28.209   5.144  1.00 48.66           O  
ANISOU  472  O5'  DC B  12     4839   6451   7196    774   1004    611       O  
ATOM    473  C5'  DC B  12     -46.704  28.940   6.374  1.00 46.53           C  
ANISOU  473  C5'  DC B  12     4494   6085   7097    666    796    514       C  
ATOM    474  C4'  DC B  12     -46.462  28.054   7.573  1.00 43.63           C  
ANISOU  474  C4'  DC B  12     4119   5748   6709    673    596    360       C  
ATOM    475  O4'  DC B  12     -47.355  26.932   7.571  1.00 39.93           O  
ANISOU  475  O4'  DC B  12     3855   5361   5953    725    568    312       O  
ATOM    476  C3'  DC B  12     -45.087  27.420   7.658  1.00 45.45           C  
ANISOU  476  C3'  DC B  12     4184   5966   7116    723    637    374       C  
ATOM    477  O3'  DC B  12     -44.112  28.344   8.170  1.00 51.06           O  
ANISOU  477  O3'  DC B  12     4629   6586   8183    665    572    341       O  
ATOM    478  C2'  DC B  12     -45.332  26.220   8.565  1.00 41.64           C  
ANISOU  478  C2'  DC B  12     3790   5563   6469    789    494    290       C  
ATOM    479  C1'  DC B  12     -46.851  26.042   8.552  1.00 38.61           C  
ANISOU  479  C1'  DC B  12     3636   5214   5819    775    457    258       C  
ATOM    480  N1   DC B  12     -47.318  24.690   8.226  1.00 35.22           N  
ANISOU  480  N1   DC B  12     3341   4799   5241    843    529    250       N  
ATOM    481  C2   DC B  12     -47.761  23.864   9.262  1.00 34.05           C  
ANISOU  481  C2   DC B  12     3236   4662   5040    895    426    237       C  
ATOM    482  O2   DC B  12     -47.757  24.303  10.424  1.00 33.84           O  
ANISOU  482  O2   DC B  12     3152   4695   5008    909    266    230       O  
ATOM    483  N3   DC B  12     -48.193  22.616   8.975  1.00 33.53           N  
ANISOU  483  N3   DC B  12     3250   4542   4945    947    516    228       N  
ATOM    484  C4   DC B  12     -48.169  22.176   7.714  1.00 35.27           C  
ANISOU  484  C4   DC B  12     3514   4732   5154    953    664    166       C  
ATOM    485  N4   DC B  12     -48.603  20.938   7.475  1.00 36.31           N  
ANISOU  485  N4   DC B  12     3691   4780   5323    999    735     93       N  
ATOM    486  C5   DC B  12     -47.712  22.993   6.640  1.00 36.15           C  
ANISOU  486  C5   DC B  12     3604   4901   5228    934    758    174       C  
ATOM    487  C6   DC B  12     -47.305  24.233   6.937  1.00 36.01           C  
ANISOU  487  C6   DC B  12     3500   4902   5277    878    706    251       C  
TER     488       DC B  12                                                      
ATOM    489  CA  GLY C 586     -76.563  24.015  19.476  1.00 53.59           C  
ANISOU  489  CA  GLY C 586     7476   6855   6028  -1087    706   1107       C  
ATOM    490  C   GLY C 586     -75.384  24.961  19.435  1.00 50.05           C  
ANISOU  490  C   GLY C 586     7064   6390   5562   -736    628    985       C  
ATOM    491  O   GLY C 586     -74.247  24.514  19.273  1.00 53.23           O  
ANISOU  491  O   GLY C 586     7696   6559   5966   -625    552    875       O  
ATOM    492  N   LYS C 587     -75.652  26.270  19.603  1.00 45.73           N  
ANISOU  492  N   LYS C 587     6276   6069   5027   -558    663   1013       N  
ATOM    493  CA  LYS C 587     -74.629  27.348  19.473  1.00 39.99           C  
ANISOU  493  CA  LYS C 587     5552   5351   4291   -268    585    899       C  
ATOM    494  C   LYS C 587     -74.593  28.224  20.700  1.00 38.89           C  
ANISOU  494  C   LYS C 587     5436   5262   4076    -48    710    943       C  
ATOM    495  O   LYS C 587     -75.637  28.677  21.182  1.00 38.58           O  
ANISOU  495  O   LYS C 587     5229   5374   4055    -64    888   1045       O  
ATOM    496  CB  LYS C 587     -74.906  28.258  18.281  1.00 37.54           C  
ANISOU  496  CB  LYS C 587     4977   5229   4056   -282    491    867       C  
ATOM    497  CG  LYS C 587     -74.626  27.643  16.955  1.00 36.79           C  
ANISOU  497  CG  LYS C 587     4938   5079   3959   -487    351    765       C  
ATOM    498  CD  LYS C 587     -75.007  28.589  15.795  1.00 35.64           C  
ANISOU  498  CD  LYS C 587     4551   5149   3839   -541    229    784       C  
ATOM    499  CE  LYS C 587     -74.065  29.785  15.661  1.00 32.04           C  
ANISOU  499  CE  LYS C 587     4090   4695   3385   -266    201    702       C  
ATOM    500  NZ  LYS C 587     -74.412  30.603  14.441  1.00 31.34           N  
ANISOU  500  NZ  LYS C 587     3819   4785   3301   -352     64    751       N  
ATOM    501  N   ARG C 588     -73.392  28.500  21.206  1.00 37.08           N  
ANISOU  501  N   ARG C 588     5411   4908   3769    145    630    864       N  
ATOM    502  CA  ARG C 588     -73.284  29.309  22.416  1.00 38.44           C  
ANISOU  502  CA  ARG C 588     5692   5107   3804    300    731    880       C  
ATOM    503  C   ARG C 588     -73.395  30.754  22.065  1.00 36.47           C  
ANISOU  503  C   ARG C 588     5254   4988   3612    447    772    811       C  
ATOM    504  O   ARG C 588     -73.016  31.197  20.950  1.00 36.70           O  
ANISOU  504  O   ARG C 588     5136   5050   3757    480    640    739       O  
ATOM    505  CB  ARG C 588     -71.988  29.078  23.161  1.00 38.06           C  
ANISOU  505  CB  ARG C 588     5931   4894   3636    408    576    855       C  
ATOM    506  CG  ARG C 588     -71.796  27.689  23.705  1.00 40.34           C  
ANISOU  506  CG  ARG C 588     6449   5004   3871    308    526    969       C  
ATOM    507  CD  ARG C 588     -70.427  27.574  24.329  1.00 42.06           C  
ANISOU  507  CD  ARG C 588     6876   5076   4026    446    305    984       C  
ATOM    508  NE  ARG C 588     -69.378  27.806  23.340  1.00 40.37           N  
ANISOU  508  NE  ARG C 588     6513   4816   4009    569    141    859       N  
ATOM    509  CZ  ARG C 588     -68.060  27.893  23.596  1.00 41.87           C  
ANISOU  509  CZ  ARG C 588     6751   4913   4241    711    -72    858       C  
ATOM    510  NH1 ARG C 588     -67.212  28.110  22.587  1.00 40.11           N  
ANISOU  510  NH1 ARG C 588     6347   4664   4227    805   -149    735       N  
ATOM    511  NH2 ARG C 588     -67.580  27.747  24.821  1.00 42.16           N  
ANISOU  511  NH2 ARG C 588     7007   4895   4116    739   -215    992       N  
ATOM    512  N   LYS C 589     -73.898  31.511  23.024  1.00 38.09           N  
ANISOU  512  N   LYS C 589     5501   5244   3728    531    980    829       N  
ATOM    513  CA  LYS C 589     -74.003  32.945  22.903  1.00 36.47           C  
ANISOU  513  CA  LYS C 589     5177   5096   3582    699   1068    762       C  
ATOM    514  C   LYS C 589     -72.899  33.566  23.729  1.00 36.00           C  
ANISOU  514  C   LYS C 589     5424   4925   3329    804   1003    642       C  
ATOM    515  O   LYS C 589     -72.477  32.979  24.741  1.00 36.43           O  
ANISOU  515  O   LYS C 589     5768   4903   3168    745    975    659       O  
ATOM    516  CB  LYS C 589     -75.394  33.415  23.400  1.00 39.51           C  
ANISOU  516  CB  LYS C 589     5391   5582   4038    730   1411    849       C  
ATOM    517  CG ALYS C 589     -76.562  32.904  22.544  0.50 39.65           C  
ANISOU  517  CG ALYS C 589     5023   5752   4288    599   1434   1004       C  
ATOM    518  CD ALYS C 589     -77.846  33.671  22.819  0.50 41.48           C  
ANISOU  518  CD ALYS C 589     4956   6097   4709    702   1757   1106       C  
ATOM    519  CE ALYS C 589     -78.897  33.372  21.777  0.50 42.54           C  
ANISOU  519  CE ALYS C 589     4628   6415   5120    573   1675   1291       C  
ATOM    520  NZ ALYS C 589     -79.517  32.048  21.987  0.50 43.86           N  
ANISOU  520  NZ ALYS C 589     4762   6641   5258    292   1712   1395       N  
ATOM    521  N   ARG C 590     -72.442  34.757  23.326  1.00 36.08           N  
ANISOU  521  N   ARG C 590     5385   4921   3400    931    960    541       N  
ATOM    522  CA  ARG C 590     -71.438  35.523  24.074  1.00 37.56           C  
ANISOU  522  CA  ARG C 590     5851   5010   3409    989    890    416       C  
ATOM    523  C   ARG C 590     -71.906  35.739  25.533  1.00 40.57           C  
ANISOU  523  C   ARG C 590     6528   5352   3532    971   1143    395       C  
ATOM    524  O   ARG C 590     -73.100  35.714  25.799  1.00 42.22           O  
ANISOU  524  O   ARG C 590     6645   5612   3782    983   1454    455       O  
ATOM    525  CB  ARG C 590     -71.179  36.869  23.412  1.00 37.93           C  
ANISOU  525  CB  ARG C 590     5794   5034   3584   1105    885    323       C  
ATOM    526  CG  ARG C 590     -72.319  37.899  23.596  1.00 42.43           C  
ANISOU  526  CG  ARG C 590     6278   5597   4245   1233   1219    327       C  
ATOM    527  CD  ARG C 590     -72.384  38.994  22.548  1.00 43.29           C  
ANISOU  527  CD  ARG C 590     6174   5686   4586   1354   1198    329       C  
ATOM    528  NE AARG C 590     -71.523  40.162  22.783  0.50 44.33           N  
ANISOU  528  NE AARG C 590     6530   5668   4646   1406   1170    178       N  
ATOM    529  CZ AARG C 590     -71.816  41.252  23.510  0.50 44.31           C  
ANISOU  529  CZ AARG C 590     6718   5515   4601   1511   1434     78       C  
ATOM    530  NH1AARG C 590     -72.952  41.397  24.185  0.50 48.43           N  
ANISOU  530  NH1AARG C 590     7236   6013   5150   1612   1804    101       N  
ATOM    531  NH2AARG C 590     -70.925  42.215  23.575  0.50 43.25           N  
ANISOU  531  NH2AARG C 590     6796   5236   4401   1500   1352    -61       N  
ATOM    532  N   CYS C 591     -70.960  35.973  26.440  1.00 39.73           N  
ANISOU  532  N   CYS C 591     6768   5165   3161    923   1012    313       N  
ATOM    533  CA  CYS C 591     -71.259  36.065  27.899  1.00 41.82           C  
ANISOU  533  CA  CYS C 591     7425   5388   3075    839   1221    283       C  
ATOM    534  C   CYS C 591     -71.865  37.429  28.235  1.00 43.83           C  
ANISOU  534  C   CYS C 591     7769   5578   3303    938   1585    130       C  
ATOM    535  O   CYS C 591     -72.734  37.547  29.128  1.00 46.39           O  
ANISOU  535  O   CYS C 591     8278   5884   3463    919   1972    105       O  
ATOM    536  CB  CYS C 591     -69.987  35.762  28.741  1.00 42.64           C  
ANISOU  536  CB  CYS C 591     7886   5439   2873    705    875    283       C  
ATOM    537  SG  CYS C 591     -68.746  37.071  28.972  1.00 39.76           S  
ANISOU  537  SG  CYS C 591     7733   4998   2374    676    645     96       S  
ATOM    538  N   GLY C 592     -71.396  38.445  27.512  1.00 42.88           N  
ANISOU  538  N   GLY C 592     7531   5401   3357   1042   1491     27       N  
ATOM    539  CA  GLY C 592     -71.881  39.817  27.619  1.00 45.55           C  
ANISOU  539  CA  GLY C 592     7930   5619   3756   1173   1815   -112       C  
ATOM    540  C   GLY C 592     -71.180  40.664  28.673  1.00 47.97           C  
ANISOU  540  C   GLY C 592     8745   5771   3709   1067   1841   -319       C  
ATOM    541  O   GLY C 592     -71.469  41.861  28.761  1.00 52.64           O  
ANISOU  541  O   GLY C 592     9448   6203   4350   1171   2117   -467       O  
ATOM    542  N   VAL C 593     -70.296  40.056  29.486  1.00 47.31           N  
ANISOU  542  N   VAL C 593     8986   5719   3270    852   1551   -318       N  
ATOM    543  CA AVAL C 593     -69.667  40.766  30.625  0.50 50.27           C  
ANISOU  543  CA AVAL C 593     9908   5973   3219    669   1536   -504       C  
ATOM    544  CA BVAL C 593     -69.680  40.732  30.643  0.50 50.45           C  
ANISOU  544  CA BVAL C 593     9932   5998   3236    667   1537   -499       C  
ATOM    545  C   VAL C 593     -68.138  40.717  30.686  1.00 49.16           C  
ANISOU  545  C   VAL C 593     9883   5856   2940    483    977   -503       C  
ATOM    546  O   VAL C 593     -67.526  41.442  31.477  1.00 51.76           O  
ANISOU  546  O   VAL C 593    10633   6090   2940    292    893   -660       O  
ATOM    547  CB AVAL C 593     -70.272  40.302  31.983  0.50 53.58           C  
ANISOU  547  CB AVAL C 593    10758   6393   3205    521   1816   -513       C  
ATOM    548  CB BVAL C 593     -70.203  40.120  31.963  0.50 53.66           C  
ANISOU  548  CB BVAL C 593    10746   6426   3214    509   1759   -481       C  
ATOM    549  CG1AVAL C 593     -71.769  40.517  31.962  0.50 54.99           C  
ANISOU  549  CG1AVAL C 593    10788   6538   3566    710   2431   -533       C  
ATOM    550  CG1BVAL C 593     -69.936  41.062  33.102  0.50 57.99           C  
ANISOU  550  CG1BVAL C 593    11906   6822   3304    324   1911   -721       C  
ATOM    551  CG2AVAL C 593     -69.971  38.835  32.281  0.50 52.93           C  
ANISOU  551  CG2AVAL C 593    10671   6459   2980    387   1500   -278       C  
ATOM    552  CG2BVAL C 593     -71.696  39.833  31.871  0.50 54.25           C  
ANISOU  552  CG2BVAL C 593    10597   6533   3481    672   2280   -416       C  
ATOM    553  N   CYS C 594     -67.514  39.907  29.853  1.00 46.51           N  
ANISOU  553  N   CYS C 594     9172   5636   2861    524    610   -334       N  
ATOM    554  CA  CYS C 594     -66.060  39.870  29.777  1.00 44.91           C  
ANISOU  554  CA  CYS C 594     8955   5465   2643    391    107   -308       C  
ATOM    555  C   CYS C 594     -65.560  41.184  29.153  1.00 45.22           C  
ANISOU  555  C   CYS C 594     8930   5407   2843    401     94   -478       C  
ATOM    556  O   CYS C 594     -66.357  41.956  28.545  1.00 44.35           O  
ANISOU  556  O   CYS C 594     8709   5205   2935    566    443   -567       O  
ATOM    557  CB  CYS C 594     -65.617  38.609  28.985  1.00 42.87           C  
ANISOU  557  CB  CYS C 594     8290   5319   2678    477   -177    -93       C  
ATOM    558  SG  CYS C 594     -66.126  38.468  27.221  1.00 34.09           S  
ANISOU  558  SG  CYS C 594     6625   4243   2082    712    -22    -60       S  
ATOM    559  N   GLU C 595     -64.278  41.477  29.311  1.00 46.52           N  
ANISOU  559  N   GLU C 595     9156   5581   2938    219   -302   -503       N  
ATOM    560  CA  GLU C 595     -63.725  42.720  28.760  1.00 46.61           C  
ANISOU  560  CA  GLU C 595     9134   5488   3088    176   -327   -657       C  
ATOM    561  C   GLU C 595     -63.919  42.805  27.224  1.00 43.39           C  
ANISOU  561  C   GLU C 595     8242   5096   3146    400   -224   -602       C  
ATOM    562  O   GLU C 595     -64.430  43.829  26.714  1.00 42.16           O  
ANISOU  562  O   GLU C 595     8092   4805   3121    495     47   -708       O  
ATOM    563  CB  GLU C 595     -62.254  42.903  29.187  1.00 49.18           C  
ANISOU  563  CB  GLU C 595     9544   5858   3285   -101   -818   -658       C  
ATOM    564  CG  GLU C 595     -61.554  44.146  28.624  1.00 50.25           C  
ANISOU  564  CG  GLU C 595     9637   5887   3569   -207   -877   -805       C  
ATOM    565  CD  GLU C 595     -60.534  44.756  29.591  1.00 55.22           C  
ANISOU  565  CD  GLU C 595    10620   6488   3871   -585  -1222   -903       C  
ATOM    566  N   PRO C 596     -63.585  41.725  26.480  1.00 40.52           N  
ANISOU  566  N   PRO C 596     7493   4878   3023    486   -413   -432       N  
ATOM    567  CA  PRO C 596     -63.931  41.785  25.042  1.00 38.10           C  
ANISOU  567  CA  PRO C 596     6810   4590   3076    660   -273   -392       C  
ATOM    568  C   PRO C 596     -65.415  42.044  24.771  1.00 38.98           C  
ANISOU  568  C   PRO C 596     6909   4654   3248    836    121   -391       C  
ATOM    569  O   PRO C 596     -65.714  42.815  23.897  1.00 39.45           O  
ANISOU  569  O   PRO C 596     6830   4654   3505    926    253   -408       O  
ATOM    570  CB  PRO C 596     -63.502  40.425  24.529  1.00 35.33           C  
ANISOU  570  CB  PRO C 596     6159   4369   2893    705   -470   -238       C  
ATOM    571  CG  PRO C 596     -62.361  40.060  25.412  1.00 37.55           C  
ANISOU  571  CG  PRO C 596     6546   4684   3037    553   -825   -196       C  
ATOM    572  CD  PRO C 596     -62.736  40.555  26.773  1.00 40.05           C  
ANISOU  572  CD  PRO C 596     7320   4937   2957    421   -774   -275       C  
ATOM    573  N   CYS C 597     -66.322  41.457  25.558  1.00 40.32           N  
ANISOU  573  N   CYS C 597     7220   4846   3254    873    305   -352       N  
ATOM    574  CA  CYS C 597     -67.769  41.594  25.311  1.00 40.23           C  
ANISOU  574  CA  CYS C 597     7105   4818   3360   1044    683   -314       C  
ATOM    575  C   CYS C 597     -68.254  43.021  25.583  1.00 42.44           C  
ANISOU  575  C   CYS C 597     7585   4906   3632   1119    987   -456       C  
ATOM    576  O   CYS C 597     -69.263  43.467  25.012  1.00 41.16           O  
ANISOU  576  O   CYS C 597     7226   4703   3709   1308   1256   -401       O  
ATOM    577  CB  CYS C 597     -68.583  40.613  26.162  1.00 42.35           C  
ANISOU  577  CB  CYS C 597     7475   5157   3459   1033    841   -237       C  
ATOM    578  SG  CYS C 597     -68.836  38.969  25.426  1.00 39.16           S  
ANISOU  578  SG  CYS C 597     6725   4921   3230   1044    694    -29       S  
ATOM    579  N   GLN C 598     -67.546  43.719  26.463  1.00 43.29           N  
ANISOU  579  N   GLN C 598     8087   4884   3475    965    935   -628       N  
ATOM    580  CA  GLN C 598     -67.910  45.065  26.822  1.00 46.75           C  
ANISOU  580  CA  GLN C 598     8805   5078   3878   1011   1246   -802       C  
ATOM    581  C   GLN C 598     -67.316  46.099  25.872  1.00 45.43           C  
ANISOU  581  C   GLN C 598     8531   4785   3943   1025   1137   -838       C  
ATOM    582  O   GLN C 598     -67.708  47.255  25.948  1.00 45.31           O  
ANISOU  582  O   GLN C 598     8702   4522   3989   1111   1418   -952       O  
ATOM    583  CB  GLN C 598     -67.536  45.363  28.279  1.00 49.37           C  
ANISOU  583  CB  GLN C 598     9704   5300   3753    785   1284  -1000       C  
ATOM    584  CG  GLN C 598     -68.325  44.504  29.276  1.00 51.20           C  
ANISOU  584  CG  GLN C 598    10113   5616   3722    773   1505   -966       C  
ATOM    585  CD  GLN C 598     -68.469  45.159  30.635  1.00 54.76           C  
ANISOU  585  CD  GLN C 598    11187   5883   3736    612   1785  -1203       C  
ATOM    586  OE1 GLN C 598     -68.845  46.322  30.719  1.00 57.34           O  
ANISOU  586  OE1 GLN C 598    11720   5955   4111    694   2140  -1391       O  
ATOM    587  NE2 GLN C 598     -68.176  44.408  31.711  1.00 56.00           N  
ANISOU  587  NE2 GLN C 598    11681   6146   3448    372   1637  -1191       N  
ATOM    588  N   GLN C 599     -66.430  45.683  24.946  1.00 42.83           N  
ANISOU  588  N   GLN C 599     7905   4602   3764    955    778   -732       N  
ATOM    589  CA  GLN C 599     -65.866  46.621  23.972  1.00 43.75           C  
ANISOU  589  CA  GLN C 599     7913   4614   4093    941    693   -742       C  
ATOM    590  C   GLN C 599     -66.992  47.177  23.135  1.00 43.53           C  
ANISOU  590  C   GLN C 599     7694   4491   4354   1200    978   -635       C  
ATOM    591  O   GLN C 599     -67.867  46.433  22.679  1.00 43.19           O  
ANISOU  591  O   GLN C 599     7359   4600   4450   1354   1052   -472       O  
ATOM    592  CB  GLN C 599     -64.823  45.940  23.053  1.00 44.05           C  
ANISOU  592  CB  GLN C 599     7626   4848   4260    836    336   -637       C  
ATOM    593  CG  GLN C 599     -63.517  45.570  23.739  1.00 46.91           C  
ANISOU  593  CG  GLN C 599     8094   5288   4440    590      0   -700       C  
ATOM    594  CD  GLN C 599     -62.797  46.768  24.304  1.00 53.25           C  
ANISOU  594  CD  GLN C 599     9225   5906   5099    374    -60   -873       C  
ATOM    595  OE1 GLN C 599     -62.586  47.748  23.605  1.00 60.08           O  
ANISOU  595  OE1 GLN C 599    10072   6633   6123    354      0   -909       O  
ATOM    596  NE2 GLN C 599     -62.428  46.707  25.592  1.00 56.77           N  
ANISOU  596  NE2 GLN C 599    10014   6338   5215    178   -189   -977       N  
ATOM    597  N   LYS C 600     -66.978  48.486  22.943  1.00 45.29           N  
ANISOU  597  N   LYS C 600     8080   4450   4675   1234   1120   -708       N  
ATOM    598  CA  LYS C 600     -67.992  49.162  22.170  1.00 45.49           C  
ANISOU  598  CA  LYS C 600     7932   4343   5010   1497   1361   -568       C  
ATOM    599  C   LYS C 600     -67.537  49.510  20.728  1.00 44.51           C  
ANISOU  599  C   LYS C 600     7558   4247   5104   1473   1151   -407       C  
ATOM    600  O   LYS C 600     -68.323  50.069  19.952  1.00 46.23           O  
ANISOU  600  O   LYS C 600     7613   4370   5581   1673   1275   -231       O  
ATOM    601  CB  LYS C 600     -68.382  50.427  22.894  1.00 49.83           C  
ANISOU  601  CB  LYS C 600     8857   4516   5558   1590   1712   -733       C  
ATOM    602  CG  LYS C 600     -68.702  50.197  24.370  1.00 53.16           C  
ANISOU  602  CG  LYS C 600     9632   4882   5682   1550   1957   -939       C  
ATOM    603  N   THR C 601     -66.284  49.246  20.385  1.00 40.55           N  
ANISOU  603  N   THR C 601     7035   3863   4508   1228    852   -451       N  
ATOM    604  CA  THR C 601     -65.790  49.572  19.044  1.00 40.23           C  
ANISOU  604  CA  THR C 601     6802   3851   4630   1164    701   -317       C  
ATOM    605  C   THR C 601     -64.801  48.498  18.541  1.00 37.48           C  
ANISOU  605  C   THR C 601     6232   3787   4221    976    424   -302       C  
ATOM    606  O   THR C 601     -64.201  47.759  19.334  1.00 36.63           O  
ANISOU  606  O   THR C 601     6162   3792   3961    867    297   -411       O  
ATOM    607  CB  THR C 601     -65.083  50.931  18.991  1.00 41.94           C  
ANISOU  607  CB  THR C 601     7283   3777   4871   1032    720   -412       C  
ATOM    608  OG1 THR C 601     -63.927  50.897  19.811  1.00 41.36           O  
ANISOU  608  OG1 THR C 601     7408   3710   4594    761    560   -619       O  
ATOM    609  CG2 THR C 601     -65.993  52.083  19.459  1.00 45.85           C  
ANISOU  609  CG2 THR C 601     8042   3909   5467   1237   1040   -445       C  
ATOM    610  N   ASN C 602     -64.648  48.446  17.229  1.00 34.80           N  
ANISOU  610  N   ASN C 602     5677   3541   4003    945    348   -158       N  
ATOM    611  CA  ASN C 602     -63.689  47.550  16.586  1.00 33.81           C  
ANISOU  611  CA  ASN C 602     5349   3635   3861    782    168   -158       C  
ATOM    612  C   ASN C 602     -62.266  48.095  16.709  1.00 33.94           C  
ANISOU  612  C   ASN C 602     5440   3588   3866    547     55   -282       C  
ATOM    613  O   ASN C 602     -62.049  49.320  16.710  1.00 34.53           O  
ANISOU  613  O   ASN C 602     5705   3446   3967    470    106   -314       O  
ATOM    614  CB  ASN C 602     -64.057  47.342  15.120  1.00 33.27           C  
ANISOU  614  CB  ASN C 602     5084   3679   3874    790    166     20       C  
ATOM    615  CG  ASN C 602     -65.410  46.691  14.951  1.00 34.17           C  
ANISOU  615  CG  ASN C 602     5070   3902   4011    964    217    163       C  
ATOM    616  OD1 ASN C 602     -65.743  45.740  15.664  1.00 34.29           O  
ANISOU  616  OD1 ASN C 602     5039   4018   3969   1023    221    115       O  
ATOM    617  ND2 ASN C 602     -66.232  47.232  14.023  1.00 33.95           N  
ANISOU  617  ND2 ASN C 602     4977   3849   4072   1033    240    369       N  
ATOM    618  N   CYS C 603     -61.288  47.195  16.825  1.00 33.76           N  
ANISOU  618  N   CYS C 603     5254   3737   3833    429    -97   -339       N  
ATOM    619  CA  CYS C 603     -59.885  47.636  16.950  1.00 35.17           C  
ANISOU  619  CA  CYS C 603     5414   3897   4051    190   -231   -429       C  
ATOM    620  C   CYS C 603     -59.347  48.313  15.693  1.00 34.53           C  
ANISOU  620  C   CYS C 603     5246   3785   4087     50   -165   -372       C  
ATOM    621  O   CYS C 603     -58.508  49.200  15.781  1.00 35.34           O  
ANISOU  621  O   CYS C 603     5423   3779   4224   -157   -210   -431       O  
ATOM    622  CB  CYS C 603     -58.990  46.495  17.380  1.00 36.49           C  
ANISOU  622  CB  CYS C 603     5365   4251   4249    138   -412   -459       C  
ATOM    623  SG  CYS C 603     -58.434  45.392  16.076  1.00 35.23           S  
ANISOU  623  SG  CYS C 603     4830   4284   4269    153   -362   -391       S  
ATOM    624  N   GLY C 604     -59.841  47.916  14.525  1.00 32.00           N  
ANISOU  624  N   GLY C 604     4799   3558   3800    126    -62   -252       N  
ATOM    625  CA  GLY C 604     -59.473  48.582  13.299  1.00 33.40           C  
ANISOU  625  CA  GLY C 604     4959   3702   4027    -19     20   -172       C  
ATOM    626  C   GLY C 604     -58.163  48.097  12.688  1.00 34.66           C  
ANISOU  626  C   GLY C 604     4880   4010   4277   -212     26   -224       C  
ATOM    627  O   GLY C 604     -57.838  48.474  11.556  1.00 38.18           O  
ANISOU  627  O   GLY C 604     5307   4463   4734   -357    141   -158       O  
ATOM    628  N   GLU C 605     -57.425  47.249  13.400  1.00 34.78           N  
ANISOU  628  N   GLU C 605     4705   4140   4367   -211    -78   -320       N  
ATOM    629  CA  GLU C 605     -56.074  46.826  12.965  1.00 36.30           C  
ANISOU  629  CA  GLU C 605     4603   4455   4732   -365    -55   -365       C  
ATOM    630  C   GLU C 605     -55.917  45.309  12.780  1.00 36.34           C  
ANISOU  630  C   GLU C 605     4367   4618   4824   -223    -13   -384       C  
ATOM    631  O   GLU C 605     -55.032  44.888  12.049  1.00 38.20           O  
ANISOU  631  O   GLU C 605     4364   4934   5213   -302    123   -412       O  
ATOM    632  CB  GLU C 605     -55.014  47.369  13.935  1.00 39.16           C  
ANISOU  632  CB  GLU C 605     4896   4784   5198   -540   -247   -430       C  
ATOM    633  CG  GLU C 605     -54.946  48.921  14.020  1.00 40.36           C  
ANISOU  633  CG  GLU C 605     5308   4735   5290   -749   -254   -441       C  
ATOM    634  CD  GLU C 605     -54.571  49.632  12.686  1.00 42.78           C  
ANISOU  634  CD  GLU C 605     5600   5003   5651   -937    -48   -377       C  
ATOM    635  OE1 GLU C 605     -54.072  48.963  11.753  1.00 42.79           O  
ANISOU  635  OE1 GLU C 605     5349   5160   5747   -964    104   -357       O  
ATOM    636  OE2 GLU C 605     -54.754  50.882  12.573  1.00 41.54           O  
ANISOU  636  OE2 GLU C 605     5711   4635   5436  -1070    -15   -348       O  
ATOM    637  N   CYS C 606     -56.794  44.503  13.365  1.00 33.56           N  
ANISOU  637  N   CYS C 606     4087   4282   4380    -21    -83   -372       N  
ATOM    638  CA  CYS C 606     -56.730  43.051  13.185  1.00 33.72           C  
ANISOU  638  CA  CYS C 606     3933   4397   4482    110    -30   -388       C  
ATOM    639  C   CYS C 606     -57.195  42.621  11.797  1.00 33.49           C  
ANISOU  639  C   CYS C 606     3937   4407   4378     91    205   -384       C  
ATOM    640  O   CYS C 606     -57.808  43.408  11.031  1.00 32.31           O  
ANISOU  640  O   CYS C 606     3962   4236   4077      1    278   -324       O  
ATOM    641  CB  CYS C 606     -57.506  42.320  14.278  1.00 32.37           C  
ANISOU  641  CB  CYS C 606     3856   4217   4223    289   -177   -364       C  
ATOM    642  SG  CYS C 606     -59.313  42.249  14.126  1.00 29.19           S  
ANISOU  642  SG  CYS C 606     3702   3795   3591    408   -106   -299       S  
ATOM    643  N   THR C 607     -56.929  41.368  11.470  1.00 33.26           N  
ANISOU  643  N   THR C 607     3771   4421   4445    166    315   -437       N  
ATOM    644  CA  THR C 607     -57.131  40.881  10.112  1.00 33.84           C  
ANISOU  644  CA  THR C 607     3902   4526   4429     86    566   -479       C  
ATOM    645  C   THR C 607     -58.627  40.907   9.794  1.00 31.05           C  
ANISOU  645  C   THR C 607     3800   4189   3808     91    514   -396       C  
ATOM    646  O   THR C 607     -59.018  41.294   8.679  1.00 31.55           O  
ANISOU  646  O   THR C 607     4005   4286   3695    -61    615   -355       O  
ATOM    647  CB  THR C 607     -56.532  39.461   9.905  1.00 37.14           C  
ANISOU  647  CB  THR C 607     4154   4929   5028    181    734   -584       C  
ATOM    648  OG1 THR C 607     -56.976  38.628  10.952  1.00 40.62           O  
ANISOU  648  OG1 THR C 607     4588   5331   5513    371    556   -550       O  
ATOM    649  CG2 THR C 607     -55.012  39.490   9.925  1.00 40.25           C  
ANISOU  649  CG2 THR C 607     4225   5321   5745    169    841   -637       C  
ATOM    650  N   TYR C 608     -59.456  40.620  10.792  1.00 28.52           N  
ANISOU  650  N   TYR C 608     3526   3852   3455    243    343   -343       N  
ATOM    651  CA  TYR C 608     -60.904  40.573  10.590  1.00 27.79           C  
ANISOU  651  CA  TYR C 608     3590   3792   3174    262    290   -242       C  
ATOM    652  C   TYR C 608     -61.481  41.987  10.427  1.00 27.87           C  
ANISOU  652  C   TYR C 608     3710   3778   3100    224    226   -113       C  
ATOM    653  O   TYR C 608     -62.376  42.183   9.624  1.00 29.01           O  
ANISOU  653  O   TYR C 608     3942   3968   3110    161    219      4       O  
ATOM    654  CB  TYR C 608     -61.593  39.805  11.694  1.00 27.63           C  
ANISOU  654  CB  TYR C 608     3569   3761   3167    423    183   -223       C  
ATOM    655  CG  TYR C 608     -60.958  38.403  11.983  1.00 28.78           C  
ANISOU  655  CG  TYR C 608     3620   3875   3438    490    227   -318       C  
ATOM    656  CD1 TYR C 608     -60.301  37.670  10.972  1.00 32.51           C  
ANISOU  656  CD1 TYR C 608     4049   4335   3969    411    417   -424       C  
ATOM    657  CD2 TYR C 608     -61.006  37.839  13.287  1.00 29.11           C  
ANISOU  657  CD2 TYR C 608     3642   3875   3543    635     98   -294       C  
ATOM    658  CE1 TYR C 608     -59.705  36.415  11.233  1.00 31.52           C  
ANISOU  658  CE1 TYR C 608     3832   4123   4018    515    490   -502       C  
ATOM    659  CE2 TYR C 608     -60.426  36.595  13.559  1.00 30.06           C  
ANISOU  659  CE2 TYR C 608     3679   3931   3809    719    118   -335       C  
ATOM    660  CZ  TYR C 608     -59.785  35.876  12.533  1.00 31.52           C  
ANISOU  660  CZ  TYR C 608     3794   4073   4110    679    318   -438       C  
ATOM    661  OH  TYR C 608     -59.192  34.610  12.768  1.00 30.18           O  
ANISOU  661  OH  TYR C 608     3538   3783   4146    803    377   -474       O  
ATOM    662  N   CYS C 609     -60.944  42.949  11.166  1.00 27.66           N  
ANISOU  662  N   CYS C 609     3685   3664   3161    248    169   -126       N  
ATOM    663  CA  CYS C 609     -61.337  44.373  10.995  1.00 29.18           C  
ANISOU  663  CA  CYS C 609     4010   3762   3314    217    147    -17       C  
ATOM    664  C   CYS C 609     -60.981  44.849   9.606  1.00 30.69           C  
ANISOU  664  C   CYS C 609     4245   3975   3438     20    243     42       C  
ATOM    665  O   CYS C 609     -61.840  45.398   8.893  1.00 31.21           O  
ANISOU  665  O   CYS C 609     4425   4034   3399     -5    216    213       O  
ATOM    666  CB  CYS C 609     -60.699  45.275  12.055  1.00 30.04           C  
ANISOU  666  CB  CYS C 609     4164   3737   3509    225     86    -85       C  
ATOM    667  SG  CYS C 609     -61.562  45.223  13.634  1.00 29.21           S  
ANISOU  667  SG  CYS C 609     4162   3559   3374    429      3   -105       S  
ATOM    668  N   LYS C 610     -59.742  44.586   9.200  1.00 30.04           N  
ANISOU  668  N   LYS C 610     4063   3930   3419   -120    358    -75       N  
ATOM    669  CA ALYS C 610     -59.242  45.045   7.896  0.60 33.15           C  
ANISOU  669  CA ALYS C 610     4520   4345   3727   -349    508    -39       C  
ATOM    670  CA BLYS C 610     -59.235  45.031   7.899  0.40 32.79           C  
ANISOU  670  CA BLYS C 610     4473   4301   3683   -348    509    -41       C  
ATOM    671  C   LYS C 610     -59.953  44.349   6.723  1.00 33.20           C  
ANISOU  671  C   LYS C 610     4638   4463   3511   -441    574     16       C  
ATOM    672  O   LYS C 610     -59.973  44.879   5.624  1.00 35.21           O  
ANISOU  672  O   LYS C 610     5043   4736   3597   -640    641    116       O  
ATOM    673  CB ALYS C 610     -57.706  44.864   7.774  0.60 34.93           C  
ANISOU  673  CB ALYS C 610     4560   4593   4117   -475    674   -190       C  
ATOM    674  CB BLYS C 610     -57.712  44.809   7.797  0.40 34.17           C  
ANISOU  674  CB BLYS C 610     4458   4499   4024   -467    673   -195       C  
ATOM    675  CG ALYS C 610     -56.864  45.895   8.529  0.60 36.91           C  
ANISOU  675  CG ALYS C 610     4738   4746   4538   -535    598   -206       C  
ATOM    676  CG BLYS C 610     -56.894  45.714   8.709  0.40 35.35           C  
ANISOU  676  CG BLYS C 610     4516   4556   4357   -496    577   -221       C  
ATOM    677  CD ALYS C 610     -56.891  47.288   7.877  0.60 38.45           C  
ANISOU  677  CD ALYS C 610     5132   4834   4642   -726    634    -81       C  
ATOM    678  CD BLYS C 610     -55.406  45.617   8.422  0.40 37.34           C  
ANISOU  678  CD BLYS C 610     4521   4858   4806   -656    739   -322       C  
ATOM    679  CE ALYS C 610     -56.044  48.285   8.652  0.60 39.71           C  
ANISOU  679  CE ALYS C 610     5252   4871   4964   -833    558   -119       C  
ATOM    680  CE BLYS C 610     -54.592  46.522   9.333  0.40 38.53           C  
ANISOU  680  CE BLYS C 610     4572   4935   5130   -748    590   -335       C  
ATOM    681  NZ ALYS C 610     -56.459  49.694   8.425  0.60 40.73           N  
ANISOU  681  NZ ALYS C 610     5658   4804   5013   -931    530     17       N  
ATOM    682  N   ASN C 611     -60.548  43.171   6.967  1.00 31.63           N  
ANISOU  682  N   ASN C 611     4399   4333   3285   -332    539    -37       N  
ATOM    683  CA  ASN C 611     -61.331  42.468   5.962  1.00 32.18           C  
ANISOU  683  CA  ASN C 611     4602   4504   3120   -458    555      6       C  
ATOM    684  C   ASN C 611     -62.829  42.396   6.293  1.00 31.48           C  
ANISOU  684  C   ASN C 611     4535   4457   2968   -347    329    180       C  
ATOM    685  O   ASN C 611     -63.524  41.463   5.868  1.00 30.07           O  
ANISOU  685  O   ASN C 611     4403   4370   2651   -422    296    182       O  
ATOM    686  CB  ASN C 611     -60.774  41.063   5.823  1.00 33.89           C  
ANISOU  686  CB  ASN C 611     4766   4741   3367   -474    741   -210       C  
ATOM    687  CG  ASN C 611     -61.205  40.384   4.521  1.00 35.91           C  
ANISOU  687  CG  ASN C 611     5239   5077   3326   -718    844   -237       C  
ATOM    688  OD1 ASN C 611     -61.449  41.053   3.505  1.00 36.08           O  
ANISOU  688  OD1 ASN C 611     5444   5158   3104   -941    830   -113       O  
ATOM    689  ND2 ASN C 611     -61.294  39.067   4.550  1.00 37.03           N  
ANISOU  689  ND2 ASN C 611     5396   5204   3468   -701    938   -391       N  
ATOM    690  N   ARG C 612     -63.343  43.396   7.010  1.00 32.80           N  
ANISOU  690  N   ARG C 612     4669   4546   3247   -186    195    325       N  
ATOM    691  CA  ARG C 612     -64.736  43.373   7.499  1.00 33.16           C  
ANISOU  691  CA  ARG C 612     4662   4618   3317    -28     33    490       C  
ATOM    692  C   ARG C 612     -65.769  43.015   6.416  1.00 34.68           C  
ANISOU  692  C   ARG C 612     4903   4958   3315   -190    -92    674       C  
ATOM    693  O   ARG C 612     -66.675  42.262   6.673  1.00 35.27           O  
ANISOU  693  O   ARG C 612     4893   5119   3389   -148   -179    716       O  
ATOM    694  CB  ARG C 612     -65.135  44.715   8.140  1.00 35.14           C  
ANISOU  694  CB  ARG C 612     4914   4723   3714    149    -25    636       C  
ATOM    695  CG  ARG C 612     -66.558  44.661   8.772  1.00 38.74           C  
ANISOU  695  CG  ARG C 612     5260   5195   4264    356   -119    792       C  
ATOM    696  CD  ARG C 612     -66.894  45.788   9.754  1.00 38.71           C  
ANISOU  696  CD  ARG C 612     5265   4993   4448    596    -78    847       C  
ATOM    697  NE  ARG C 612     -65.891  45.854  10.791  1.00 36.72           N  
ANISOU  697  NE  ARG C 612     5084   4628   4237    632     19    603       N  
ATOM    698  CZ  ARG C 612     -64.831  46.667  10.808  1.00 36.94           C  
ANISOU  698  CZ  ARG C 612     5229   4523   4284    543     61    513       C  
ATOM    699  NH1 ARG C 612     -64.616  47.583   9.849  1.00 36.77           N  
ANISOU  699  NH1 ARG C 612     5297   4427   4244    426     54    645       N  
ATOM    700  NH2 ARG C 612     -63.962  46.550  11.817  1.00 36.26           N  
ANISOU  700  NH2 ARG C 612     5171   4380   4227    544     91    304       N  
ATOM    701  N   LYS C 613     -65.639  43.555   5.216  1.00 36.16           N  
ANISOU  701  N   LYS C 613     5235   5182   3320   -407   -120    798       N  
ATOM    702  CA  LYS C 613     -66.697  43.331   4.227  1.00 39.14           C  
ANISOU  702  CA  LYS C 613     5670   5714   3485   -591   -318   1024       C  
ATOM    703  C   LYS C 613     -66.847  41.835   3.825  1.00 39.25           C  
ANISOU  703  C   LYS C 613     5742   5861   3308   -790   -289    856       C  
ATOM    704  O   LYS C 613     -67.933  41.418   3.404  1.00 42.22           O  
ANISOU  704  O   LYS C 613     6101   6377   3562   -915   -498   1022       O  
ATOM    705  CB  LYS C 613     -66.493  44.231   2.997  1.00 42.68           C  
ANISOU  705  CB  LYS C 613     6321   6173   3720   -824   -376   1218       C  
ATOM    706  CG  LYS C 613     -65.262  43.925   2.158  1.00 44.82           C  
ANISOU  706  CG  LYS C 613     6810   6455   3764  -1102   -131    996       C  
ATOM    707  N   ASN C 614     -65.768  41.045   3.959  1.00 35.52           N  
ANISOU  707  N   ASN C 614     5327   5330   2839   -822    -33    541       N  
ATOM    708  CA  ASN C 614     -65.760  39.616   3.596  1.00 35.01           C  
ANISOU  708  CA  ASN C 614     5366   5312   2624   -993     64    339       C  
ATOM    709  C   ASN C 614     -65.744  38.650   4.802  1.00 33.53           C  
ANISOU  709  C   ASN C 614     5021   5046   2672   -764    129    177       C  
ATOM    710  O   ASN C 614     -66.143  37.502   4.673  1.00 32.94           O  
ANISOU  710  O   ASN C 614     5013   4990   2510   -875    141     84       O  
ATOM    711  CB  ASN C 614     -64.557  39.370   2.692  1.00 37.01           C  
ANISOU  711  CB  ASN C 614     5824   5522   2714  -1204    359    115       C  
ATOM    712  CG  ASN C 614     -64.627  40.223   1.428  1.00 40.51           C  
ANISOU  712  CG  ASN C 614     6492   6053   2847  -1495    299    289       C  
ATOM    713  OD1 ASN C 614     -65.633  40.203   0.740  1.00 41.20           O  
ANISOU  713  OD1 ASN C 614     6702   6272   2680  -1706     53    488       O  
ATOM    714  ND2 ASN C 614     -63.576  40.993   1.147  1.00 41.00           N  
ANISOU  714  ND2 ASN C 614     6598   6047   2932  -1523    499    244       N  
ATOM    715  N   SER C 615     -65.337  39.122   5.969  1.00 31.89           N  
ANISOU  715  N   SER C 615     4639   4742   2733   -476    152    161       N  
ATOM    716  CA  SER C 615     -65.057  38.218   7.101  1.00 30.32           C  
ANISOU  716  CA  SER C 615     4335   4457   2728   -282    223     10       C  
ATOM    717  C   SER C 615     -66.330  37.881   7.812  1.00 29.41           C  
ANISOU  717  C   SER C 615     4130   4393   2649   -192     63    145       C  
ATOM    718  O   SER C 615     -67.206  38.766   8.001  1.00 29.23           O  
ANISOU  718  O   SER C 615     4018   4429   2657   -118    -81    358       O  
ATOM    719  CB  SER C 615     -64.072  38.876   8.074  1.00 30.24           C  
ANISOU  719  CB  SER C 615     4206   4342   2941    -67    276    -50       C  
ATOM    720  OG  SER C 615     -63.920  38.117   9.270  1.00 28.74           O  
ANISOU  720  OG  SER C 615     3926   4082   2910    117    272   -129       O  
ATOM    721  N   HIS C 616     -66.456  36.626   8.249  1.00 27.22           N  
ANISOU  721  N   HIS C 616     3862   4075   2402   -184    110     36       N  
ATOM    722  CA  HIS C 616     -67.578  36.212   9.086  1.00 26.07           C  
ANISOU  722  CA  HIS C 616     3618   3969   2315   -104      3    151       C  
ATOM    723  C   HIS C 616     -67.178  36.206  10.584  1.00 25.43           C  
ANISOU  723  C   HIS C 616     3458   3781   2421    165     48    107       C  
ATOM    724  O   HIS C 616     -67.871  35.593  11.398  1.00 26.70           O  
ANISOU  724  O   HIS C 616     3581   3939   2621    223     27    154       O  
ATOM    725  CB  HIS C 616     -68.090  34.807   8.692  1.00 27.05           C  
ANISOU  725  CB  HIS C 616     3843   4100   2334   -310     13     85       C  
ATOM    726  CG  HIS C 616     -68.521  34.655   7.249  1.00 26.92           C  
ANISOU  726  CG  HIS C 616     3968   4194   2064   -650    -55    109       C  
ATOM    727  ND1 HIS C 616     -69.238  33.561   6.813  1.00 28.22           N  
ANISOU  727  ND1 HIS C 616     4243   4388   2089   -911   -102     81       N  
ATOM    728  CD2 HIS C 616     -68.328  35.433   6.155  1.00 29.03           C  
ANISOU  728  CD2 HIS C 616     4326   4543   2158   -810    -96    161       C  
ATOM    729  CE1 HIS C 616     -69.475  33.676   5.515  1.00 30.32           C  
ANISOU  729  CE1 HIS C 616     4669   4764   2084  -1232   -189    108       C  
ATOM    730  NE2 HIS C 616     -68.929  34.807   5.091  1.00 30.06           N  
ANISOU  730  NE2 HIS C 616     4632   4769   2020  -1171   -185    167       N  
ATOM    731  N   GLN C 617     -66.073  36.877  10.953  1.00 27.30           N  
ANISOU  731  N   GLN C 617     3684   3938   2749    290     97     29       N  
ATOM    732  CA  GLN C 617     -65.514  36.798  12.295  1.00 27.89           C  
ANISOU  732  CA  GLN C 617     3727   3919   2950    482     96    -20       C  
ATOM    733  C   GLN C 617     -65.518  38.127  13.013  1.00 28.78           C  
ANISOU  733  C   GLN C 617     3821   4016   3098    604     50     40       C  
ATOM    734  O   GLN C 617     -65.225  39.185  12.419  1.00 29.04           O  
ANISOU  734  O   GLN C 617     3858   4049   3126    564     51     62       O  
ATOM    735  CB  GLN C 617     -64.099  36.243  12.211  1.00 30.21           C  
ANISOU  735  CB  GLN C 617     4009   4118   3349    497    173   -173       C  
ATOM    736  CG  GLN C 617     -64.100  34.790  11.745  1.00 31.65           C  
ANISOU  736  CG  GLN C 617     4253   4238   3534    423    269   -258       C  
ATOM    737  CD  GLN C 617     -62.727  34.201  11.709  1.00 36.97           C  
ANISOU  737  CD  GLN C 617     4871   4785   4390    497    384   -391       C  
ATOM    738  OE1 GLN C 617     -62.027  34.309  10.722  1.00 45.00           O  
ANISOU  738  OE1 GLN C 617     5883   5791   5422    409    537   -497       O  
ATOM    739  NE2 GLN C 617     -62.354  33.550  12.763  1.00 37.03           N  
ANISOU  739  NE2 GLN C 617     4831   4692   4543    657    322   -368       N  
ATOM    740  N   ILE C 618     -65.838  38.094  14.295  1.00 28.04           N  
ANISOU  740  N   ILE C 618     3748   3884   3020    733     29     62       N  
ATOM    741  CA  ILE C 618     -65.788  39.316  15.088  1.00 27.90           C  
ANISOU  741  CA  ILE C 618     3782   3807   3010    832     23     72       C  
ATOM    742  C   ILE C 618     -64.345  39.824  15.266  1.00 25.68           C  
ANISOU  742  C   ILE C 618     3523   3456   2777    807    -27    -37       C  
ATOM    743  O   ILE C 618     -63.387  39.020  15.216  1.00 25.33           O  
ANISOU  743  O   ILE C 618     3417   3408   2796    778    -61   -108       O  
ATOM    744  CB  ILE C 618     -66.530  39.103  16.445  1.00 29.38           C  
ANISOU  744  CB  ILE C 618     4041   3972   3149    940     57    103       C  
ATOM    745  CG1 ILE C 618     -66.899  40.461  17.052  1.00 30.28           C  
ANISOU  745  CG1 ILE C 618     4243   4004   3255   1035    131    113       C  
ATOM    746  CG2 ILE C 618     -65.733  38.205  17.357  1.00 29.88           C  
ANISOU  746  CG2 ILE C 618     4174   3994   3183    945    -16     36       C  
ATOM    747  CD1 ILE C 618     -67.679  40.391  18.352  1.00 34.89           C  
ANISOU  747  CD1 ILE C 618     4937   4555   3764   1128    244    121       C  
ATOM    748  N   CYS C 619     -64.192  41.147  15.440  1.00 25.22           N  
ANISOU  748  N   CYS C 619     3533   3328   2720    814    -24    -41       N  
ATOM    749  CA  CYS C 619     -62.912  41.774  15.788  1.00 26.97           C  
ANISOU  749  CA  CYS C 619     3782   3482   2982    750    -95   -136       C  
ATOM    750  C   CYS C 619     -62.177  40.930  16.844  1.00 28.96           C  
ANISOU  750  C   CYS C 619     4023   3742   3238    766   -219   -190       C  
ATOM    751  O   CYS C 619     -62.787  40.494  17.825  1.00 27.47           O  
ANISOU  751  O   CYS C 619     3941   3546   2950    838   -237   -166       O  
ATOM    752  CB  CYS C 619     -63.132  43.172  16.363  1.00 28.97           C  
ANISOU  752  CB  CYS C 619     4204   3607   3195    765    -72   -149       C  
ATOM    753  SG  CYS C 619     -61.637  43.897  17.049  1.00 31.09           S  
ANISOU  753  SG  CYS C 619     4541   3793   3475    618   -207   -273       S  
ATOM    754  N   LYS C 620     -60.889  40.702  16.658  1.00 28.07           N  
ANISOU  754  N   LYS C 620     3770   3643   3249    697   -301   -237       N  
ATOM    755  CA  LYS C 620     -60.150  39.804  17.588  1.00 29.03           C  
ANISOU  755  CA  LYS C 620     3830   3774   3425    731   -466   -228       C  
ATOM    756  C   LYS C 620     -60.130  40.368  18.996  1.00 30.17           C  
ANISOU  756  C   LYS C 620     4174   3879   3410    697   -626   -232       C  
ATOM    757  O   LYS C 620     -60.042  39.625  19.982  1.00 30.67           O  
ANISOU  757  O   LYS C 620     4296   3950   3406    730   -769   -180       O  
ATOM    758  CB  LYS C 620     -58.722  39.582  17.113  1.00 30.35           C  
ANISOU  758  CB  LYS C 620     3741   3964   3827    680   -519   -253       C  
ATOM    759  CG  LYS C 620     -58.591  38.710  15.863  1.00 30.44           C  
ANISOU  759  CG  LYS C 620     3591   3988   3985    716   -321   -279       C  
ATOM    760  CD  LYS C 620     -57.129  38.449  15.524  1.00 31.77           C  
ANISOU  760  CD  LYS C 620     3468   4163   4438    701   -317   -305       C  
ATOM    761  CE  LYS C 620     -56.966  37.878  14.116  1.00 33.24           C  
ANISOU  761  CE  LYS C 620     3558   4339   4731    692    -24   -384       C  
ATOM    762  NZ  LYS C 620     -55.626  37.331  13.828  1.00 36.09           N  
ANISOU  762  NZ  LYS C 620     3604   4679   5429    740     62   -412       N  
ATOM    763  N   LYS C 621     -60.220  41.688  19.115  1.00 31.95           N  
ANISOU  763  N   LYS C 621     4549   4041   3549    612   -597   -294       N  
ATOM    764  CA  LYS C 621     -60.240  42.305  20.443  1.00 35.67           C  
ANISOU  764  CA  LYS C 621     5292   4444   3816    538   -707   -342       C  
ATOM    765  C   LYS C 621     -61.621  42.280  21.121  1.00 35.47           C  
ANISOU  765  C   LYS C 621     5517   4368   3589    646   -539   -339       C  
ATOM    766  O   LYS C 621     -61.722  42.610  22.318  1.00 36.47           O  
ANISOU  766  O   LYS C 621     5927   4435   3493    582   -582   -394       O  
ATOM    767  CB  LYS C 621     -59.613  43.704  20.376  1.00 39.42           C  
ANISOU  767  CB  LYS C 621     5858   4826   4293    369   -739   -434       C  
ATOM    768  CG  LYS C 621     -58.103  43.589  20.085  1.00 44.79           C  
ANISOU  768  CG  LYS C 621     6262   5586   5167    221   -949   -421       C  
ATOM    769  CD  LYS C 621     -57.319  44.893  20.231  1.00 49.56           C  
ANISOU  769  CD  LYS C 621     6958   6108   5763    -20  -1042   -506       C  
ATOM    770  CE  LYS C 621     -55.806  44.638  20.360  1.00 52.85           C  
ANISOU  770  CE  LYS C 621     7071   6641   6367   -191  -1322   -464       C  
ATOM    771  N   ARG C 622     -62.665  41.863  20.390  1.00 32.05           N  
ANISOU  771  N   ARG C 622     4985   3968   3224    783   -345   -274       N  
ATOM    772  CA  ARG C 622     -64.032  41.727  20.936  1.00 32.49           C  
ANISOU  772  CA  ARG C 622     5181   4003   3158    894   -155   -242       C  
ATOM    773  C   ARG C 622     -64.529  40.298  21.124  1.00 30.35           C  
ANISOU  773  C   ARG C 622     4837   3827   2868    949   -157   -147       C  
ATOM    774  O   ARG C 622     -65.606  40.095  21.693  1.00 31.18           O  
ANISOU  774  O   ARG C 622     5043   3930   2871   1009      4   -111       O  
ATOM    775  CB  ARG C 622     -65.024  42.483  20.023  1.00 32.34           C  
ANISOU  775  CB  ARG C 622     5086   3946   3255    993     55   -198       C  
ATOM    776  CG  ARG C 622     -64.621  43.932  19.790  1.00 34.97           C  
ANISOU  776  CG  ARG C 622     5526   4134   3626    949     85   -269       C  
ATOM    777  CD  ARG C 622     -65.579  44.632  18.868  1.00 34.39           C  
ANISOU  777  CD  ARG C 622     5363   4008   3695   1068    252   -167       C  
ATOM    778  NE  ARG C 622     -66.784  45.026  19.556  1.00 36.79           N  
ANISOU  778  NE  ARG C 622     5776   4216   3987   1228    483   -150       N  
ATOM    779  CZ  ARG C 622     -67.726  45.836  19.043  1.00 37.96           C  
ANISOU  779  CZ  ARG C 622     5858   4266   4299   1382    652    -41       C  
ATOM    780  NH1 ARG C 622     -67.625  46.335  17.792  1.00 36.70           N  
ANISOU  780  NH1 ARG C 622     5559   4102   4283   1370    574     80       N  
ATOM    781  NH2 ARG C 622     -68.788  46.150  19.797  1.00 38.92           N  
ANISOU  781  NH2 ARG C 622     6053   4286   4449   1553    913    -37       N  
ATOM    782  N   LYS C 623     -63.784  39.302  20.604  1.00 29.69           N  
ANISOU  782  N   LYS C 623     4569   3803   2906    928   -301   -106       N  
ATOM    783  CA  LYS C 623     -64.132  37.910  20.765  1.00 27.67           C  
ANISOU  783  CA  LYS C 623     4277   3582   2652    965   -309    -20       C  
ATOM    784  C   LYS C 623     -64.272  37.570  22.268  1.00 28.39           C  
ANISOU  784  C   LYS C 623     4613   3648   2523    945   -375     19       C  
ATOM    785  O   LYS C 623     -63.365  37.798  23.040  1.00 31.09           O  
ANISOU  785  O   LYS C 623     5067   3969   2776    878   -576      5       O  
ATOM    786  CB  LYS C 623     -63.045  37.040  20.103  1.00 28.69           C  
ANISOU  786  CB  LYS C 623     4209   3714   2977    963   -439     -8       C  
ATOM    787  CG  LYS C 623     -63.244  35.535  20.206  1.00 29.68           C  
ANISOU  787  CG  LYS C 623     4318   3810   3147   1006   -446     75       C  
ATOM    788  CD  LYS C 623     -64.409  35.086  19.358  1.00 29.42           C  
ANISOU  788  CD  LYS C 623     4248   3807   3122    992   -255     85       C  
ATOM    789  CE  LYS C 623     -64.675  33.592  19.486  1.00 30.77           C  
ANISOU  789  CE  LYS C 623     4453   3912   3326    995   -244    156       C  
ATOM    790  NZ  LYS C 623     -65.598  33.117  18.413  1.00 29.83           N  
ANISOU  790  NZ  LYS C 623     4276   3823   3233    916    -96    143       N  
ATOM    791  N   CYS C 624     -65.405  37.012  22.636  1.00 28.77           N  
ANISOU  791  N   CYS C 624     4743   3710   2476    973   -214     83       N  
ATOM    792  CA  CYS C 624     -65.745  36.740  24.042  1.00 32.10           C  
ANISOU  792  CA  CYS C 624     5448   4111   2637    930   -201    125       C  
ATOM    793  C   CYS C 624     -64.747  35.774  24.622  1.00 34.75           C  
ANISOU  793  C   CYS C 624     5837   4425   2939    886   -489    224       C  
ATOM    794  O   CYS C 624     -64.446  34.773  23.990  1.00 30.81           O  
ANISOU  794  O   CYS C 624     5153   3910   2642    936   -561    298       O  
ATOM    795  CB  CYS C 624     -67.141  36.150  24.118  1.00 33.34           C  
ANISOU  795  CB  CYS C 624     5602   4299   2764    955     52    200       C  
ATOM    796  SG  CYS C 624     -67.666  35.456  25.681  1.00 36.12           S  
ANISOU  796  SG  CYS C 624     6290   4634   2799    872    127    288       S  
ATOM    797  N   GLU C 625     -64.238  36.061  25.828  1.00 37.34           N  
ANISOU  797  N   GLU C 625     6435   4739   3012    787   -658    234       N  
ATOM    798  CA  GLU C 625     -63.234  35.160  26.470  1.00 41.88           C  
ANISOU  798  CA  GLU C 625     7047   5299   3565    747  -1007    392       C  
ATOM    799  C   GLU C 625     -63.802  33.784  26.742  1.00 41.11           C  
ANISOU  799  C   GLU C 625     7007   5159   3451    784   -962    561       C  
ATOM    800  O   GLU C 625     -63.083  32.813  26.662  1.00 41.65           O  
ANISOU  800  O   GLU C 625     6958   5171   3694    840  -1180    706       O  
ATOM    801  CB  GLU C 625     -62.667  35.718  27.801  1.00 46.72           C  
ANISOU  801  CB  GLU C 625     7996   5926   3830    571  -1248    402       C  
ATOM    802  CG  GLU C 625     -62.033  37.101  27.719  1.00 51.61           C  
ANISOU  802  CG  GLU C 625     8633   6556   4420    469  -1325    231       C  
ATOM    803  CD  GLU C 625     -60.654  37.156  27.041  1.00 54.84           C  
ANISOU  803  CD  GLU C 625     8684   6999   5154    478  -1630    266       C  
ATOM    804  OE1 GLU C 625     -60.222  36.166  26.421  1.00 56.93           O  
ANISOU  804  OE1 GLU C 625     8637   7262   5729    615  -1713    393       O  
ATOM    805  OE2 GLU C 625     -59.992  38.225  27.136  1.00 57.57           O  
ANISOU  805  OE2 GLU C 625     9065   7355   5454    334  -1757    155       O  
ATOM    806  N   GLU C 626     -65.102  33.697  27.016  1.00 41.23           N  
ANISOU  806  N   GLU C 626     7179   5185   3301    758   -657    548       N  
ATOM    807  CA  GLU C 626     -65.762  32.381  27.230  1.00 42.50           C  
ANISOU  807  CA  GLU C 626     7400   5296   3450    752   -576    709       C  
ATOM    808  C   GLU C 626     -65.971  31.585  25.949  1.00 38.91           C  
ANISOU  808  C   GLU C 626     6642   4800   3340    841   -491    716       C  
ATOM    809  O   GLU C 626     -66.001  30.361  25.990  1.00 40.95           O  
ANISOU  809  O   GLU C 626     6927   4958   3673    842   -535    854       O  
ATOM    810  CB  GLU C 626     -67.099  32.531  27.982  1.00 44.58           C  
ANISOU  810  CB  GLU C 626     7905   5597   3434    663   -245    703       C  
ATOM    811  CG  GLU C 626     -67.023  33.369  29.245  1.00 47.23           C  
ANISOU  811  CG  GLU C 626     8623   5953   3368    544   -235    646       C  
ATOM    812  CD  GLU C 626     -66.017  32.818  30.243  1.00 51.72           C  
ANISOU  812  CD  GLU C 626     9459   6487   3704    433   -629    813       C  
ATOM    813  OE1 GLU C 626     -65.930  31.575  30.364  1.00 51.80           O  
ANISOU  813  OE1 GLU C 626     9470   6434   3774    439   -761   1026       O  
ATOM    814  OE2 GLU C 626     -65.306  33.624  30.887  1.00 55.09           O  
ANISOU  814  OE2 GLU C 626    10095   6936   3899    326   -828    747       O  
ATOM    815  N   LEU C 627     -66.111  32.257  24.807  1.00 37.68           N  
ANISOU  815  N   LEU C 627     6239   4700   3376    893   -372    570       N  
ATOM    816  CA  LEU C 627     -66.243  31.553  23.508  1.00 34.48           C  
ANISOU  816  CA  LEU C 627     5596   4261   3243    927   -304    550       C  
ATOM    817  C   LEU C 627     -64.900  31.024  22.969  1.00 36.46           C  
ANISOU  817  C   LEU C 627     5704   4410   3739   1013   -503    552       C  
ATOM    818  O   LEU C 627     -64.896  30.218  22.046  1.00 36.94           O  
ANISOU  818  O   LEU C 627     5650   4387   3995   1030   -428    530       O  
ATOM    819  CB  LEU C 627     -66.889  32.447  22.465  1.00 31.49           C  
ANISOU  819  CB  LEU C 627     5031   3987   2945    925   -129    428       C  
ATOM    820  CG  LEU C 627     -68.334  32.860  22.820  1.00 31.33           C  
ANISOU  820  CG  LEU C 627     5049   4056   2797    880    111    453       C  
ATOM    821  CD1 LEU C 627     -68.935  33.713  21.729  1.00 30.31           C  
ANISOU  821  CD1 LEU C 627     4696   4022   2798    900    226    393       C  
ATOM    822  CD2 LEU C 627     -69.234  31.643  23.161  1.00 32.76           C  
ANISOU  822  CD2 LEU C 627     5295   4215   2936    784    218    578       C  
ATOM    823  N   LYS C 628     -63.782  31.518  23.488  1.00 36.59           N  
ANISOU  823  N   LYS C 628     5714   4432   3756   1052   -732    568       N  
ATOM    824  CA  LYS C 628     -62.469  31.014  23.089  1.00 39.00           C  
ANISOU  824  CA  LYS C 628     5820   4645   4349   1157   -911    604       C  
ATOM    825  C   LYS C 628     -62.229  29.664  23.715  1.00 43.59           C  
ANISOU  825  C   LYS C 628     6497   5066   4999   1219  -1042    804       C  
ATOM    826  O   LYS C 628     -61.502  28.849  23.156  1.00 45.37           O  
ANISOU  826  O   LYS C 628     6553   5146   5540   1344  -1065    839       O  
ATOM    827  CB  LYS C 628     -61.360  31.977  23.525  1.00 39.95           C  
ANISOU  827  CB  LYS C 628     5864   4844   4469   1144  -1157    594       C  
ATOM    828  CG  LYS C 628     -61.357  33.264  22.728  1.00 38.12           C  
ANISOU  828  CG  LYS C 628     5514   4715   4252   1096  -1030    404       C  
ATOM    829  CD  LYS C 628     -60.382  34.244  23.299  1.00 40.25           C  
ANISOU  829  CD  LYS C 628     5767   5049   4475   1022  -1273    392       C  
ATOM    830  CE  LYS C 628     -60.584  35.608  22.667  1.00 37.82           C  
ANISOU  830  CE  LYS C 628     5436   4806   4127    949  -1120    215       C  
ATOM    831  NZ  LYS C 628     -59.783  36.598  23.401  1.00 39.66           N  
ANISOU  831  NZ  LYS C 628     5742   5077   4249    818  -1352    191       N  
ATOM    832  N   LYS C 629     -62.827  29.443  24.891  1.00 46.58           N  
ANISOU  832  N   LYS C 629     7165   5451   5082   1133  -1103    942       N  
ATOM    833  CA  LYS C 629     -62.766  28.147  25.587  1.00 50.30           C  
ANISOU  833  CA  LYS C 629     7796   5751   5563   1163  -1225   1177       C  
ATOM    834  C   LYS C 629     -63.770  27.173  24.946  1.00 49.78           C  
ANISOU  834  C   LYS C 629     7775   5561   5575   1135   -940   1152       C  
ATOM    835  O   LYS C 629     -64.868  27.583  24.506  1.00 47.15           O  
ANISOU  835  O   LYS C 629     7452   5342   5121   1024   -686   1016       O  
ATOM    836  CB  LYS C 629     -63.087  28.324  27.072  1.00 53.12           C  
ANISOU  836  CB  LYS C 629     8502   6173   5509   1026  -1369   1332       C  
ATOM    837  CG  LYS C 629     -62.158  29.285  27.814  1.00 56.44           C  
ANISOU  837  CG  LYS C 629     8956   6717   5772    975  -1684   1353       C  
ATOM    838  CD  LYS C 629     -62.648  29.553  29.247  1.00 59.62           C  
ANISOU  838  CD  LYS C 629     9799   7189   5663    777  -1755   1450       C  
ATOM    839  CE  LYS C 629     -61.816  30.632  29.939  1.00 61.97           C  
ANISOU  839  CE  LYS C 629    10190   7613   5741    654  -2055   1417       C  
ATOM    840  NZ  LYS C 629     -62.570  31.379  30.986  1.00 62.80           N  
ANISOU  840  NZ  LYS C 629    10748   7805   5309    432  -1921   1333       N  
ATOM    841  N   LYS C 630     -63.394  25.897  24.905  1.00 49.65           N  
ANISOU  841  N   LYS C 630     7784   5302   5779   1226   -997   1298       N  
ATOM    842  CA  LYS C 630     -64.207  24.820  24.298  1.00 50.49           C  
ANISOU  842  CA  LYS C 630     7972   5230   5980   1168   -753   1276       C  
ATOM    843  C   LYS C 630     -65.554  24.641  25.008  1.00 49.35           C  
ANISOU  843  C   LYS C 630     8089   5152   5509    958   -615   1356       C  
ATOM    844  O   LYS C 630     -65.675  24.942  26.204  1.00 50.19           O  
ANISOU  844  O   LYS C 630     8396   5346   5328    896   -730   1500       O  
ATOM    845  CB  LYS C 630     -63.428  23.495  24.357  1.00 53.67           C  
ANISOU  845  CB  LYS C 630     8408   5295   6686   1328   -856   1451       C  
TER     846      LYS C 630                                                      
HETATM  847  UNK UNX A 101     -77.889  32.186   6.701  1.00 42.93           X  
HETATM  848  UNK UNX A 102     -65.556  33.671   2.888  1.00 36.21           X  
HETATM  849  UNK UNX A 103     -60.481  37.820   7.123  1.00 39.89           X  
HETATM  850  UNK UNX B 101     -60.245  25.056   5.470  1.00 43.59           X  
HETATM  851  UNK UNX B 102     -68.763  40.136  12.998  1.00 32.94           X  
HETATM  852  UNK UNX B 103     -63.750  23.190   5.481  1.00 38.26           X  
HETATM  853  UNK UNX B 104     -72.393  40.918   8.590  0.50 24.21           X  
HETATM  854  UNK UNX B 105     -71.528  37.012  19.831  1.00 30.31           X  
HETATM  855  UNK UNX B 106     -74.050  33.056  19.320  1.00 32.78           X  
HETATM  856 ZN    ZN C 701     -67.955  37.400  26.844  1.00 35.92          ZN  
HETATM  857 ZN    ZN C 702     -60.190  44.178  15.203  1.00 28.83          ZN  
HETATM  858  UNK UNX C 703     -63.527  33.344  15.658  1.00 39.32           X  
HETATM  859  UNK UNX C 704     -68.314  40.894   7.865  1.00 22.32           X  
HETATM  860  UNK UNX C 705     -67.862  43.352  22.074  1.00 31.75           X  
HETATM  861  UNK UNX C 706     -73.853  35.611  20.606  1.00 37.14           X  
HETATM  862  UNK UNX C 707     -77.538  30.495  20.291  1.00 38.04           X  
HETATM  863  UNK UNX C 708     -54.819  40.109  13.261  1.00 31.13           X  
HETATM  864  UNK UNX C 709     -71.495  30.699  26.839  1.00 45.56           X  
HETATM  865  UNK UNX C 710     -69.210  26.921  27.716  1.00 42.92           X  
HETATM  866  O   HOH A 201     -74.600  28.944  12.161  1.00 37.34           O  
HETATM  867  O   HOH A 202     -56.051  20.607  14.597  1.00 40.17           O  
HETATM  868  O   HOH A 203     -68.094  26.749   6.177  1.00 45.18           O  
HETATM  869  O   HOH A 204     -76.496  31.899  15.985  1.00 29.42           O  
HETATM  870  O   HOH A 205     -72.912  34.376   4.095  1.00 50.12           O  
HETATM  871  O   HOH A 206     -64.604  34.724   7.450  1.00 28.26           O  
HETATM  872  O   HOH A 207     -78.229  35.442  16.247  1.00 39.26           O  
HETATM  873  O   HOH A 208     -81.969  30.314  10.072  1.00 44.69           O  
HETATM  874  O   HOH A 209     -54.971  29.865   8.541  1.00 39.03           O  
HETATM  875  O   HOH A 210     -52.176  29.159  12.147  1.00 46.39           O  
HETATM  876  O   HOH A 211     -70.646  32.553   2.598  1.00 42.29           O  
HETATM  877  O   HOH A 212     -84.811  30.776  11.238  1.00 48.68           O  
HETATM  878  O   HOH A 213     -76.545  32.405  18.544  1.00 43.11           O  
HETATM  879  O   HOH B 201     -65.741  18.644  15.577  1.00 31.51           O  
HETATM  880  O   HOH B 202     -51.780  20.217   5.643  1.00 40.13           O  
HETATM  881  O   HOH B 203     -68.964  43.406  15.826  1.00 42.10           O  
HETATM  882  O   HOH B 204     -55.290  19.741   9.965  1.00 34.95           O  
HETATM  883  O   HOH B 205     -66.065  35.283  15.270  1.00 27.30           O  
HETATM  884  O   HOH B 206     -72.565  32.896  14.750  1.00 30.05           O  
HETATM  885  O   HOH B 207     -69.125  16.007  12.624  1.00 51.73           O  
HETATM  886  O   HOH B 208     -67.656  37.111  20.710  1.00 25.64           O  
HETATM  887  O   HOH B 209     -61.246  24.697  15.592  1.00 50.35           O  
HETATM  888  O   HOH B 210     -71.376  24.819  20.472  1.00 45.15           O  
HETATM  889  O   HOH B 211     -75.298  36.345  15.706  1.00 38.24           O  
HETATM  890  O   HOH B 212     -63.002  18.683  12.592  1.00 34.76           O  
HETATM  891  O   HOH B 213     -79.843  41.220  11.045  0.50 35.48           O  
HETATM  892  O   HOH B 214     -74.699  36.454   5.803  1.00 36.37           O  
HETATM  893  O   HOH B 215     -43.136  30.315   6.226  0.50 38.87           O  
HETATM  894  O   HOH B 216     -63.291  27.740  15.385  1.00 43.20           O  
HETATM  895  O   HOH B 217     -48.917  19.945   4.625  1.00 45.33           O  
HETATM  896  O   HOH B 218     -64.628  21.051  16.208  1.00 43.98           O  
HETATM  897  O   HOH B 219     -66.928  22.829   8.397  1.00 47.62           O  
HETATM  898  O   HOH B 220     -68.201  18.885  16.320  1.00 44.60           O  
HETATM  899  O   HOH B 221     -73.838  34.318  16.710  1.00 35.76           O  
HETATM  900  O   HOH C 801     -59.144  34.010  15.221  1.00 40.15           O  
HETATM  901  O   HOH C 802     -59.273  37.211  19.678  1.00 38.85           O  
HETATM  902  O   HOH C 803     -58.733  50.161   9.602  1.00 38.27           O  
HETATM  903  O   HOH C 804     -60.820  38.872  22.521  1.00 32.06           O  
HETATM  904  O   HOH C 805     -64.999  41.455  11.004  1.00 33.89           O  
HETATM  905  O   HOH C 806     -62.248  35.978   8.616  1.00 45.12           O  
HETATM  906  O   HOH C 807     -69.497  48.196  17.231  1.00 51.15           O  
HETATM  907  O   HOH C 808     -54.120  35.955  15.597  1.00 53.90           O  
HETATM  908  O   HOH C 809     -57.307  41.436   6.577  1.00 35.34           O  
HETATM  909  O   HOH C 810     -62.004  46.872  20.662  0.50 38.53           O  
HETATM  910  O   HOH C 811     -61.584  51.203  14.798  1.00 37.55           O  
HETATM  911  O   HOH C 812     -65.516  48.262   7.354  1.00 45.75           O  
HETATM  912  O   HOH C 813     -62.864  36.453  16.048  1.00 28.84           O  
HETATM  913  O   HOH C 814     -66.372  43.126  15.087  1.00 29.50           O  
HETATM  914  O   HOH C 815     -68.168  39.276  22.330  1.00 31.26           O  
HETATM  915  O   HOH C 816     -66.262  30.538  19.202  1.00 32.13           O  
HETATM  916  O   HOH C 817     -62.822  46.845   6.729  1.00 40.76           O  
HETATM  917  O   HOH C 818     -62.078  48.519  10.892  1.00 31.86           O  
HETATM  918  O   HOH C 819     -63.552  45.482   4.538  1.00 37.23           O  
HETATM  919  O   HOH C 820     -60.203  32.952  27.147  0.50 37.35           O  
HETATM  920  O   HOH C 821     -65.312  43.569  12.528  1.00 40.28           O  
HETATM  921  O   HOH C 822     -64.930  50.173  24.486  0.50 35.06           O  
HETATM  922  O   HOH C 823     -69.119  45.711  14.348  1.00 49.36           O  
HETATM  923  O   HOH C 824     -60.735  35.523  17.314  1.00 36.66           O  
CONECT  537  856                                                                
CONECT  558  856                                                                
CONECT  578  856                                                                
CONECT  623  857                                                                
CONECT  642  857                                                                
CONECT  667  857                                                                
CONECT  753  857                                                                
CONECT  796  856                                                                
CONECT  856  537  558  578  796                                                 
CONECT  857  623  642  667  753                                                 
MASTER      363    0   19    3    0    0    3    6  911    3   10    6          
END

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Related entries of code: 6asd

Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code	Check Database	Protein Sequence Similarity
3qmb	RCSB PDB PDBbind	12aa, >3QMB_2\|Chains... *
4hp1	RCSB PDB PDBbind	12aa, >4HP1_1\|Chains... at 100%
6cnp	RCSB PDB PDBbind	12aa, >6CNP_2\|Chains... at 100%
Complexes with the same small molecule ligand
PDB Code	Check Database	Ligand Name
4z3c	RCSB PDB PDBbind	CpG DNA (5-GCCAACGTTGGC-3)
5vc9	RCSB PDB PDBbind	CpG DNA (5-GCCAACGTTGGC-3)
5w9q	RCSB PDB PDBbind	CpG DNA (5-GCCAACGTTGGC-3)
5w9s	RCSB PDB PDBbind	CpG DNA (5-GCCAACGTTGGC-3)
6asb	RCSB PDB PDBbind	CpG DNA (5-GCCAACGTTGGC-3)

Entry Information

PDB ID	6asd
Complex Type	Protein-Nucleic Acid
PDBbind Subset	general set
Protein Name	Zinc finger region of human TET1
Ligand Name	CpG DNA (5-GCCAACGTTGGC-3)
EC.Number	E.C.1.14.11.n2
Resolution	1.85(Å)
Affinity (Kd/Ki/IC50)	Kd=2.4uM
Release Year	2017
Protein/NA Sequence	Check fasta file
Primary Reference	(2017) Structure Vol. 26: pp. 85-95

Links to External Databases

RCSB PDB	The mother database
PDBsum	Enhanced annotations on PDB entries
Pubchem	Comprehensive collection of chemical and biological data
UniProtKB AC	UniProt accession number (AC): Q8NFU7
Entrez Gene ID	NCBI Entrez Gene ID: 80312
ASD	Information of known allosteric effects of PDB entries

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