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Related entries of code: 6bgy
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5islRCSB PDB    PDBbind330aa, >5ISL:A|PDBID|CHAIN|... *
5ivcRCSB PDB    PDBbind330aa, >5IVC:A|PDBID|CHAIN|... at 100%
5iveRCSB PDB    PDBbind330aa, >5IVE:A|PDBID|CHAIN|... at 100%
5ivfRCSB PDB    PDBbind330aa, >5IVF:A|PDBID|CHAIN|... at 100%
5ivjRCSB PDB    PDBbind330aa, >5IVJ:A|PDBID|CHAIN|... at 100%
5ivvRCSB PDB    PDBbind330aa, >5IVV:A|PDBID|CHAIN|... at 100%
5ivyRCSB PDB    PDBbind330aa, >5IVY:A|PDBID|CHAIN|... at 100%
5iw0RCSB PDB    PDBbind330aa, >5IW0:A|PDBID|CHAIN|... at 100%
6bguRCSB PDB    PDBbind330aa, >6BGU:A|PDBID|CHAIN|... at 100%
6bgvRCSB PDB    PDBbind330aa, >6BGV:A|PDBID|CHAIN|... at 100%
6bgwRCSB PDB    PDBbind330aa, >6BGW:A|PDBID|CHAIN|... at 100%
6bgxRCSB PDB    PDBbind330aa, >6BGX:A|PDBID|CHAIN|... at 100%
6bgzRCSB PDB    PDBbind330aa, >6BGZ:A|PDBID|CHAIN|... at 100%
6bh0RCSB PDB    PDBbind330aa, >6BH0:A|PDBID|CHAIN|... at 100%
6bh1RCSB PDB    PDBbind330aa, >6BH1:A|PDBID|CHAIN|... at 100%
6bh2RCSB PDB    PDBbind330aa, >6BH2:A|PDBID|CHAIN|... at 100%
6bh3RCSB PDB    PDBbind330aa, >6BH3:A|PDBID|CHAIN|... at 100%
6bh5RCSB PDB    PDBbind330aa, >6BH5:A|PDBID|CHAIN|... at 100%
6dq4RCSB PDB    PDBbind330aa, >6DQ4:A|PDBID|CHAIN|... at 100%
6dq5RCSB PDB    PDBbind330aa, >6DQ5:A|PDBID|CHAIN|... at 100%
6dq6RCSB PDB    PDBbind330aa, >6DQ6:A|PDBID|CHAIN|... at 100%
6dq8RCSB PDB    PDBbind330aa, >6DQ8:A|PDBID|CHAIN|... at 100%
6dqaRCSB PDB    PDBbind330aa, >6DQA:A|PDBID|CHAIN|... at 100%
6dqbRCSB PDB    PDBbind330aa, >6DQB:A|PDBID|CHAIN|... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID6bgy
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameLysine-specific demethylase 5A, linked KDM5A JMJ domain
Ligand NameDLJ
EC.Number E.C.1.14.11.-
Resolution 1.22(Å)
Affinity (Kd/Ki/IC50)Kd=0.15uM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) J. Med. Chem. Vol. 61: pp. 3193-3208
Ligand Properties
Formula C22H22ClN3O3
Molecular Weight 411.881
Exact Mass 411.135
No. of atoms 51
No. of bonds 54
Polar Surface Area 78.45
LOGP Value 4.64      (Computed with XLOGP3)
4.57      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 7
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P29375  
Entrez Gene IDNCBI Entrez Gene ID: 5927  
ASDInformation of known allosteric effects of PDB entries

 
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