Browse entries in the PDBbind-CN Database

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Related entries of code: 6e7u
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3qelRCSB PDB    PDBbind364aa, >3QEL_2|Chains... *
3qemRCSB PDB    PDBbind364aa, >3QEM_2|Chains... at 100%
5ewjRCSB PDB    PDBbind364aa, >5EWJ_2|Chains... at 99%
5ewmRCSB PDB    PDBbind364aa, >5EWM_2|Chains... at 99%
6e7xRCSB PDB    PDBbind363aa, >6E7X_2|Chains... at 100%
6e7wRCSB PDB    PDBbind363aa, >6E7W_2|Chains... at 100%
6e7vRCSB PDB    PDBbind363aa, >6E7V_2|Chains... at 100%
6e7tRCSB PDB    PDBbind363aa, >6E7T_2|Chains... at 100%
6e7sRCSB PDB    PDBbind363aa, >6E7S_2|Chains... at 100%
6e7rRCSB PDB    PDBbind363aa, >6E7R_2|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6e7u
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameGluN1b-GluN2B NMDA receptor
Ligand NameHX7
EC.Number E.C.-.-.-.-
Resolution 2.27(Å)
Affinity (Kd/Ki/IC50)Kd=121nM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Nat Commun Vol. 10: pp. 321-
Ligand Properties
Formula C22H31Cl2N2O4S
Molecular Weight 490.464
Exact Mass 489.138
No. of atoms 62
No. of bonds 63
Polar Surface Area 88.45
LOGP Value 4.74      (Computed with XLOGP3)
4.19      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 14
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): A0A1L8F5J9  Q00960  
Entrez Gene IDNCBI Entrez Gene ID: 397953  24410  
ASDInformation of known allosteric effects of PDB entries
 
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