Browse entries in the PDBbind-CN Database

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Related entries of code: 6mvx
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5klsRCSB PDB    PDBbind285aa, >5KLS_1|Chains... *
5kmfRCSB PDB    PDBbind285aa, >5KMF_1|Chains... at 99%
5kmhRCSB PDB    PDBbind285aa, >5KMH_1|Chains... at 100%
6kebRCSB PDB    PDBbind284aa, >6KEB_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6mvx
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameNavAb voltage-gated sodium channel
Ligand NameK4D
EC.Number E.C.-.-.-.-
Resolution 3.46(Å)
Affinity (Kd/Ki/IC50)IC50=7.2uM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) Proc. Natl. Acad. Sci. U.S.A. Vol. 115: pp. 13111-13116
Ligand Properties
Formula C17H21F6N2O3
Molecular Weight 415.351
Exact Mass 415.146
No. of atoms 49
No. of bonds 50
Polar Surface Area 64.17
LOGP Value 3.85      (Computed with XLOGP3)
4.37      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 1
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): A8EVM5  
Entrez Gene IDNo matched NCBI Entrez Gene ID found!
ASDInformation of known allosteric effects of PDB entries
 
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