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Related entries of code: 6r1w
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5oh1RCSB PDB    PDBbind125aa, >5OH1_1|Chains... *
5oh2RCSB PDB    PDBbind125aa, >5OH2_1|Chains... at 100%
5oh3RCSB PDB    PDBbind125aa, >5OH3_1|Chains... at 100%
5oh4RCSB PDB    PDBbind125aa, >5OH4_1|Chains... at 100%
5oh7RCSB PDB    PDBbind125aa, >5OH7_1|Chains... at 100%
5oh9RCSB PDB    PDBbind125aa, >5OH9_1|Chains... at 100%
5ohaRCSB PDB    PDBbind125aa, >5OHA_1|Chains... at 100%
6r1xRCSB PDB    PDBbind125aa, >6R1X_1|Chains... at 100%
6r1kRCSB PDB    PDBbind125aa, >6R1K_1|Chains... at 100%
6r1dRCSB PDB    PDBbind125aa, >6R1D_1|Chains... at 100%
6r1cRCSB PDB    PDBbind125aa, >6R1C_1|Chains... at 100%
6r1aRCSB PDB    PDBbind125aa, >6R1A_1|Chains... at 100%
6r18RCSB PDB    PDBbind125aa, >6R18_1|Chains... at 100%
6r13RCSB PDB    PDBbind125aa, >6R13_1|Chains... at 100%
6r12RCSB PDB    PDBbind125aa, >6R12_1|Chains... at 100%
6r0sRCSB PDB    PDBbind125aa, >6R0S_1|Chains... at 100%
6r0uRCSB PDB    PDBbind125aa, >6R0U_1|Chains... at 100%
6r0vRCSB PDB    PDBbind125aa, >6R0V_1|Chains... at 100%
6r11RCSB PDB    PDBbind125aa, >6R11_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6r1w
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameCereblon isoform 4
Ligand NameJPW
EC.Number E.C.-.-.-.-
Resolution 1.35(Å)
Affinity (Kd/Ki/IC50)Ki=5.0uM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) J.Med.Chem. Vol. 62: pp. 6615-6629
Ligand Properties
Formula C13H22N3O4
Molecular Weight 284.331
Exact Mass 284.161
No. of atoms 42
No. of bonds 43
Polar Surface Area 112.14
LOGP Value -0.24      (Computed with XLOGP3)
0.04      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): A4TVL0  
Entrez Gene IDNo matched NCBI Entrez Gene ID found!
ASDInformation of known allosteric effects of PDB entries
 
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