Browse entries in the PDBbind-CN Database
HEADER TRANSFERASE 28-APR-05 2BQZ TITLE CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE TITLE 2 METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8) COMPND MOL_ID: 1; COMPND 2 MOLECULE: SET8 PROTEIN; COMPND 3 CHAIN: A, E; COMPND 4 FRAGMENT: SET-DOMAIN, RESIDUES 192-352; COMPND 5 SYNONYM: HISTONE-LYSINE METHYLTRANSFERASE PR-SET7; COMPND 6 EC: 2.1.1.43; COMPND 7 ENGINEERED: YES; COMPND 8 MOL_ID: 2; COMPND 9 MOLECULE: HISTONE H4; COMPND 10 CHAIN: B, F; COMPND 11 FRAGMENT: RESIDUES 17-25 SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 7 MOL_ID: 2; SOURCE 8 SYNTHETIC: YES; SOURCE 9 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 10 ORGANISM_COMMON: HUMAN; SOURCE 11 ORGANISM_TAXID: 9606 KEYWDS HISTONE H4 METHYLTRANSFERSAE, LYSINE METHYLTRANSFERASE, SET KEYWDS 2 DOMAIN, TRANSFERASE EXPDTA X-RAY DIFFRACTION AUTHOR B.XIAO,C.JING,G.KELLY,P.A.WALKER,F.W.MUSKETT,T.A.FRENKIEL, AUTHOR 2 S.R.MARTIN,K.SARMA,D.REINBERG,S.J.GAMBLIN,J.R.WILSON REVDAT 3 24-FEB-09 2BQZ 1 VERSN REVDAT 2 23-JUN-05 2BQZ 1 SOURCE JRNL REVDAT 1 08-JUN-05 2BQZ 0 JRNL AUTH B.XIAO,C.JING,G.KELLY,P.A.WALKER,F.W.MUSKETT, JRNL AUTH 2 T.A.FRENKIEL,S.R.MARTIN,K.SARMA,D.REINBERG, JRNL AUTH 3 S.J.GAMBLIN,J.R.WILSON JRNL TITL SPECIFICITY AND MECHANISM OF THE HISTONE JRNL TITL 2 METHYLTRANSFERASE PR-SET7 JRNL REF GENES DEV. V. 19 1444 2005 JRNL REFN ISSN 0890-9369 JRNL PMID 15933069 JRNL DOI 10.1101/GAD.1315905 REMARK 2 REMARK 2 RESOLUTION. 1.5 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.0 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.50 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 20.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 COMPLETENESS FOR RANGE (%) : 94.0 REMARK 3 NUMBER OF REFLECTIONS : 50828 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.188 REMARK 3 R VALUE (WORKING SET) : 0.187 REMARK 3 FREE R VALUE : 0.206 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.000 REMARK 3 FREE R VALUE TEST SET COUNT : 2663 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 1.50 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 1.54 REMARK 3 REFLECTION IN BIN (WORKING SET) : 3734 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : NULL REMARK 3 BIN R VALUE (WORKING SET) : 0.2550 REMARK 3 BIN FREE R VALUE SET COUNT : 202 REMARK 3 BIN FREE R VALUE : 0.3090 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 2754 REMARK 3 NUCLEIC ACID ATOMS : 0 REMARK 3 HETEROGEN ATOMS : 70 REMARK 3 SOLVENT ATOMS : 613 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 13.44 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 1.79000 REMARK 3 B22 (A**2) : -1.87000 REMARK 3 B33 (A**2) : -0.24000 REMARK 3 B12 (A**2) : 0.58000 REMARK 3 B13 (A**2) : -0.10000 REMARK 3 B23 (A**2) : 0.41000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.121 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.084 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.074 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 3.934 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.957 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.952 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 2870 ; 0.011 ; 0.021 REMARK 3 BOND LENGTHS OTHERS (A): 2568 ; 0.001 ; 0.020 REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 3840 ; 1.579 ; 1.985 REMARK 3 BOND ANGLES OTHERS (DEGREES): 5988 ; 0.722 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 334 ; 4.432 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): NULL ; NULL ; NULL REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 537 ;16.125 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): NULL ; NULL ; NULL REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 408 ; 0.094 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 3136 ; 0.006 ; 0.020 REMARK 3 GENERAL PLANES OTHERS (A): 592 ; 0.003 ; 0.020 REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): 639 ; 0.322 ; 0.300 REMARK 3 NON-BONDED CONTACTS OTHERS (A): 2633 ; 0.229 ; 0.300 REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): 1 ; 0.139 ; 0.500 REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): 479 ; 0.211 ; 0.500 REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): 58 ; 0.267 ; 0.300 REMARK 3 SYMMETRY VDW OTHERS (A): 114 ; 0.352 ; 0.300 REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): 46 ; 0.258 ; 0.500 REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 1694 ; 0.893 ; 1.500 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 2696 ; 1.580 ; 2.000 REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 1176 ; 2.112 ; 3.000 REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): 1144 ; 3.299 ; 4.500 REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 3 REMARK 3 REMARK 3 TLS GROUP : 1 REMARK 3 NUMBER OF COMPONENTS GROUP : 2 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : A 192 A 352 REMARK 3 RESIDUE RANGE : B 17 B 26 REMARK 3 ORIGIN FOR THE GROUP (A): -2.8050 0.7050 1.9790 REMARK 3 T TENSOR REMARK 3 T11: 0.3989 T22: 0.5214 REMARK 3 T33: 0.4322 T12: -0.0297 REMARK 3 T13: -0.0190 T23: -0.0244 REMARK 3 L TENSOR REMARK 3 L11: 1.5402 L22: 1.7726 REMARK 3 L33: 1.5966 L12: 0.2290 REMARK 3 L13: -0.1745 L23: -0.0687 REMARK 3 S TENSOR REMARK 3 S11: -0.0472 S12: -0.0387 S13: -0.1173 REMARK 3 S21: -0.0102 S22: 0.0294 S23: 0.0137 REMARK 3 S31: 0.0422 S32: -0.0663 S33: 0.0177 REMARK 3 REMARK 3 TLS GROUP : 2 REMARK 3 NUMBER OF COMPONENTS GROUP : 2 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : E 192 E 352 REMARK 3 RESIDUE RANGE : F 17 F 26 REMARK 3 ORIGIN FOR THE GROUP (A): 14.1550 26.9770 20.1650 REMARK 3 T TENSOR REMARK 3 T11: 0.4327 T22: 0.5326 REMARK 3 T33: 0.4111 T12: -0.0875 REMARK 3 T13: 0.0116 T23: -0.0141 REMARK 3 L TENSOR REMARK 3 L11: 1.5824 L22: 1.6109 REMARK 3 L33: 2.3888 L12: 0.2192 REMARK 3 L13: 0.8310 L23: 0.7914 REMARK 3 S TENSOR REMARK 3 S11: 0.0145 S12: -0.0078 S13: 0.0454 REMARK 3 S21: 0.0666 S22: 0.0286 S23: -0.1147 REMARK 3 S31: -0.1309 S32: 0.1389 S33: -0.0431 REMARK 3 REMARK 3 TLS GROUP : 3 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : W 1 W 613 REMARK 3 ORIGIN FOR THE GROUP (A): 3.9830 12.2940 10.3700 REMARK 3 T TENSOR REMARK 3 T11: 0.1487 T22: 0.2792 REMARK 3 T33: 0.1570 T12: -0.0264 REMARK 3 T13: -0.0046 T23: -0.0061 REMARK 3 L TENSOR REMARK 3 L11: 0.5180 L22: 0.8035 REMARK 3 L33: 0.8133 L12: 0.3728 REMARK 3 L13: 0.2167 L23: 0.3249 REMARK 3 S TENSOR REMARK 3 S11: 0.0287 S12: -0.0274 S13: -0.0673 REMARK 3 S21: -0.0098 S22: -0.0156 S23: 0.0136 REMARK 3 S31: -0.0115 S32: -0.0037 S33: -0.0132 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : BABINET MODEL WITH MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.40 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE REMARK 3 RIDING POSITIONS. REMARK 4 REMARK 4 2BQZ COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 29-APR-05. REMARK 100 THE PDBE ID CODE IS EBI-23835. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : NULL REMARK 200 TEMPERATURE (KELVIN) : 100.0 REMARK 200 PH : 7.00 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : ESRF REMARK 200 BEAMLINE : ID14-2 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9794 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO REMARK 200 DATA SCALING SOFTWARE : SCALEPACK REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 63273 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.500 REMARK 200 RESOLUTION RANGE LOW (A) : 19.900 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 2.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 89.1 REMARK 200 DATA REDUNDANCY : 4.300 REMARK 200 R MERGE (I) : 0.07000 REMARK 200 R SYM (I) : NULL REMARK 200
FOR THE DATA SET : 9.5000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : NULL REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : NULL REMARK 200 COMPLETENESS FOR SHELL (%) : NULL REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : NULL REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200
FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: OTHER REMARK 200 SOFTWARE USED: NULL REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 34.92 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 1.90 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: NULL REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1, 2 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 300 REMARK 300 DETAILS:THE DIMER IN THIS ENTRY IS FORMED BY THE REMARK 300 COMPLEXOF CHAIN A WITH A PEPTIDE CHAIN B AND REMARK 300 CHAIN E WITHPEPTIDE CHAIN F. CHAINS A AND E REMARK 300 ARE MONOMERIC IN THEPHYSIOLOGICAL STATE. REMARK 350 REMARK 350 GENERATING THE BIOMOLECULE REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PQS REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMOLECULE: 2 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PQS REMARK 350 APPLY THE FOLLOWING TO CHAINS: E, F REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 SG CYS A 305 - O HOH A 2238 2.14 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS REMARK 500 REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC REMARK 500 SYMMETRY ARE IN CLOSE CONTACT. AN ATOM LOCATED WITHIN 0.15 REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375 REMARK 500 INSTEAD OF REMARK 500. ATOMS WITH NON-BLANK ALTERNATE REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS. REMARK 500 REMARK 500 DISTANCE CUTOFF: REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI SSYMOP DISTANCE REMARK 500 REMARK 500 OE2 GLU A 197 NH2 ARG E 238 1455 2.12 REMARK 500 NH2 ARG E 238 OE2 GLU A 197 1655 2.12 REMARK 500 O HOH A 2167 O HOH A 2196 1456 2.14 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 ASP A 265 CB - CG - OD2 ANGL. DEV. = 5.6 DEGREES REMARK 500 ASP A 313 CB - CG - OD2 ANGL. DEV. = 5.9 DEGREES REMARK 500 ARG A 324 NE - CZ - NH2 ANGL. DEV. = 4.7 DEGREES REMARK 500 ARG E 192 CB - CA - C ANGL. DEV. = -14.7 DEGREES REMARK 500 LYS E 193 N - CA - C ANGL. DEV. = -25.1 DEGREES REMARK 500 ASP E 313 CB - CG - OD2 ANGL. DEV. = 5.6 DEGREES REMARK 500 ASN F 25 N - CA - C ANGL. DEV. = 16.4 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 SER A 194 172.63 -56.63 REMARK 500 GLU A 215 65.38 -119.67 REMARK 500 VAL A 242 -60.72 -107.09 REMARK 500 ASP B 24 113.58 -4.43 REMARK 500 ASN B 25 52.88 -145.37 REMARK 500 LYS E 193 -155.81 60.97 REMARK 500 VAL E 242 -60.43 -106.29 REMARK 500 ASP F 24 -99.77 172.52 REMARK 500 ASN F 25 164.89 64.31 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CHIRAL CENTERS REMARK 500 REMARK 500 UNEXPECTED CONFIGURATION OF THE FOLLOWING CHIRAL REMARK 500 CENTER(S) USING IMPROPER CA--C--CB--N CHIRALITY REMARK 500 M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,6X,F5.1,6X,A1,10X,A1,3X,A16) REMARK 500 REMARK 500 M RES CSSEQI IMPROPER EXPECTED FOUND DETAILS REMARK 500 LYS E 193 47.3 L L OUTSIDE RANGE REMARK 500 ASN F 25 22.8 L L OUTSIDE RANGE REMARK 500 REMARK 500 REMARK: NULL REMARK 525 REMARK 525 SOLVENT REMARK 525 REMARK 525 THE SOLVENT MOLECULES HAVE CHAIN IDENTIFIERS THAT REMARK 525 INDICATE THE POLYMER CHAIN WITH WHICH THEY ARE MOST REMARK 525 CLOSELY ASSOCIATED. THE REMARK LISTS ALL THE SOLVENT REMARK 525 MOLECULES WHICH ARE MORE THAN 5A AWAY FROM THE REMARK 525 NEAREST POLYMER CHAIN (M = MODEL NUMBER; REMARK 525 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE REMARK 525 NUMBER; I=INSERTION CODE): REMARK 610 REMARK 610 MISSING HETEROATOM REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 610 I=INSERTION CODE): REMARK 610 M RES C SSEQI REMARK 610 SAH A 1354 REMARK 610 SAH E 1354 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SAH A1354 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SAH E1354 REMARK 999 REMARK 999 SEQUENCE REMARK 999 THE SEQUENCE OF CHAINS A AND E CORRESPONDS MOST CLOSELY TO REMARK 999 THE NCBI ENTRY NP_065115. THERE IS A SINGLE SEQUENCE DIFFERENCE REMARK 999 BETWEEN NP_065115 AND UNIPROT ENTRY Q86W83, AT POSITION 316, REMARK 999 WHICH IS GIVEN AS PRO IN THE NCBI ENTRY BUT ARG IN UNIPROT. DBREF 2BQZ A 192 352 UNP Q86W83 Q86W83_HUMAN 192 352 DBREF 2BQZ E 192 352 UNP Q86W83 Q86W83_HUMAN 192 352 DBREF 2BQZ B 17 25 UNP P62805 H4_HUMAN 17 25 DBREF 2BQZ B 26 26 PDB 2BQZ 2BQZ 26 26 DBREF 2BQZ F 17 25 UNP P62805 H4_HUMAN 17 25 DBREF 2BQZ F 26 26 PDB 2BQZ 2BQZ 26 26 SEQADV 2BQZ PRO A 316 UNP Q86W83 ARG 316 CONFLICT SEE REMARK 999 SEQADV 2BQZ PRO E 316 UNP Q86W83 ARG 316 CONFLICT SEE REMARK 999 SEQRES 1 A 161 ARG LYS SER LYS ALA GLU LEU GLN SER GLU GLU ARG LYS SEQRES 2 A 161 ARG ILE ASP GLU LEU ILE GLU SER GLY LYS GLU GLU GLY SEQRES 3 A 161 MET LYS ILE ASP LEU ILE ASP GLY LYS GLY ARG GLY VAL SEQRES 4 A 161 ILE ALA THR LYS GLN PHE SER ARG GLY ASP PHE VAL VAL SEQRES 5 A 161 GLU TYR HIS GLY ASP LEU ILE GLU ILE THR ASP ALA LYS SEQRES 6 A 161 LYS ARG GLU ALA LEU TYR ALA GLN ASP PRO SER THR GLY SEQRES 7 A 161 CYS TYR MET TYR TYR PHE GLN TYR LEU SER LYS THR TYR SEQRES 8 A 161 CYS VAL ASP ALA THR ARG GLU THR ASN ARG LEU GLY ARG SEQRES 9 A 161 LEU ILE ASN HIS SER LYS CYS GLY ASN CYS GLN THR LYS SEQRES 10 A 161 LEU HIS ASP ILE ASP GLY VAL PRO HIS LEU ILE LEU ILE SEQRES 11 A 161 ALA SER ARG ASP ILE ALA ALA GLY GLU GLU LEU LEU TYR SEQRES 12 A 161 ASP TYR GLY ASP ARG SER LYS ALA SER ILE GLU ALA HIS SEQRES 13 A 161 PRO TRP LEU LYS HIS SEQRES 1 B 10 ARG HIS ARG MLZ VAL LEU ARG ASP ASN TYR SEQRES 1 E 161 ARG LYS SER LYS ALA GLU LEU GLN SER GLU GLU ARG LYS SEQRES 2 E 161 ARG ILE ASP GLU LEU ILE GLU SER GLY LYS GLU GLU GLY SEQRES 3 E 161 MET LYS ILE ASP LEU ILE ASP GLY LYS GLY ARG GLY VAL SEQRES 4 E 161 ILE ALA THR LYS GLN PHE SER ARG GLY ASP PHE VAL VAL SEQRES 5 E 161 GLU TYR HIS GLY ASP LEU ILE GLU ILE THR ASP ALA LYS SEQRES 6 E 161 LYS ARG GLU ALA LEU TYR ALA GLN ASP PRO SER THR GLY SEQRES 7 E 161 CYS TYR MET TYR TYR PHE GLN TYR LEU SER LYS THR TYR SEQRES 8 E 161 CYS VAL ASP ALA THR ARG GLU THR ASN ARG LEU GLY ARG SEQRES 9 E 161 LEU ILE ASN HIS SER LYS CYS GLY ASN CYS GLN THR LYS SEQRES 10 E 161 LEU HIS ASP ILE ASP GLY VAL PRO HIS LEU ILE LEU ILE SEQRES 11 E 161 ALA SER ARG ASP ILE ALA ALA GLY GLU GLU LEU LEU TYR SEQRES 12 E 161 ASP TYR GLY ASP ARG SER LYS ALA SER ILE GLU ALA HIS SEQRES 13 E 161 PRO TRP LEU LYS HIS SEQRES 1 F 10 ARG HIS ARG MLZ VAL LEU ARG ASP ASN TYR MODRES 2BQZ MLZ B 20 LYS N-METHYL-LYSINE MODRES 2BQZ MLZ F 20 LYS N-METHYL-LYSINE HET MLZ B 20 10 HET MLZ F 20 10 HET SAH A1354 25 HET SAH E1354 25 HETNAM MLZ N-METHYL-LYSINE HETNAM SAH S-ADENOSYL-L-HOMOCYSTEINE FORMUL 2 MLZ 2(C7 H16 N2 O2) FORMUL 5 SAH 2(C14 H20 N6 O5 S) FORMUL 7 HOH *613(H2 O1) HELIX 1 1 SER A 194 GLY A 213 1 20 HELIX 2 2 ILE A 252 GLN A 264 1 13 HELIX 3 3 LEU A 293 ILE A 297 5 5 HELIX 4 4 SER A 340 HIS A 347 1 8 HELIX 5 5 PRO A 348 HIS A 352 5 5 HELIX 6 6 SER E 194 GLY E 213 1 20 HELIX 7 7 ILE E 252 GLN E 264 1 13 HELIX 8 8 LEU E 293 ILE E 297 5 5 HELIX 9 9 SER E 340 HIS E 347 1 8 HELIX 10 10 PRO E 348 HIS E 352 5 5 SHEET 1 AA 2 MET A 218 ILE A 223 0 SHEET 2 AA 2 GLY A 227 ALA A 232 -1 O GLY A 227 N ILE A 223 SHEET 1 AB 3 PHE A 241 TYR A 245 0 SHEET 2 AB 3 VAL A 315 ALA A 322 -1 O LEU A 318 N TYR A 245 SHEET 3 AB 3 CYS A 305 ILE A 312 -1 O GLN A 306 N ILE A 321 SHEET 1 AC 3 ASP A 248 GLU A 251 0 SHEET 2 AC 3 LYS A 280 ASP A 285 -1 O CYS A 283 N ILE A 250 SHEET 3 AC 3 MET A 272 TYR A 277 -1 O TYR A 273 N VAL A 284 SHEET 1 AD 2 ASN A 298 HIS A 299 0 SHEET 2 AD 2 LEU A 333 TYR A 334 1 N TYR A 334 O ASN A 298 SHEET 1 EA 2 MET E 218 ILE E 223 0 SHEET 2 EA 2 GLY E 227 ALA E 232 -1 O GLY E 227 N ILE E 223 SHEET 1 EB 3 PHE E 241 GLU E 244 0 SHEET 2 EB 3 VAL E 315 ALA E 322 -1 O LEU E 320 N VAL E 242 SHEET 3 EB 3 CYS E 305 ILE E 312 -1 O GLN E 306 N ILE E 321 SHEET 1 EC 3 ASP E 248 GLU E 251 0 SHEET 2 EC 3 LYS E 280 ASP E 285 -1 O CYS E 283 N ILE E 250 SHEET 3 EC 3 MET E 272 TYR E 277 -1 O TYR E 273 N VAL E 284 SHEET 1 ED 2 ASN E 298 HIS E 299 0 SHEET 2 ED 2 LEU E 333 TYR E 334 1 N TYR E 334 O ASN E 298 LINK C ARG B 19 N MLZ B 20 1555 1555 1.34 LINK C MLZ B 20 N VAL B 21 1555 1555 1.44 LINK C ARG F 19 N MLZ F 20 1555 1555 1.31 LINK C MLZ F 20 N VAL F 21 1555 1555 1.39 SITE 1 AC1 16 GLY A 225 LYS A 226 ARG A 228 TYR A 271 SITE 2 AC1 16 ARG A 295 LEU A 296 ASN A 298 HIS A 299 SITE 3 AC1 16 TYR A 336 TRP A 349 HOH A2315 HOH A2317 SITE 4 AC1 16 HOH A2318 HIS B 18 MLZ B 20 HOH E2136 SITE 1 AC2 20 HOH A2159 ARG B 23 HOH B2012 GLY E 225 SITE 2 AC2 20 LYS E 226 ARG E 228 TYR E 271 ARG E 295 SITE 3 AC2 20 LEU E 296 ASN E 298 HIS E 299 TYR E 336 SITE 4 AC2 20 TRP E 349 HOH E2123 HOH E2245 HOH E2246 SITE 5 AC2 20 HOH E2247 HOH E2248 HIS F 18 MLZ F 20 CRYST1 42.179 46.322 51.998 64.74 86.66 90.61 P 1 2 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.023708 0.000252 -0.001651 0.00000 SCALE2 0.000000 0.021589 -0.010227 0.00000 SCALE3 0.000000 0.000000 0.021316 0.00000 MTRIX1 1 -0.983220 -0.122620 0.135050 11.66670 1 MTRIX2 1 -0.047420 -0.543070 -0.838350 32.69479 1 MTRIX3 1 0.176140 -0.830690 0.528140 11.51827 1 ATOM 1 N ARG A 192 -18.692 13.639 28.022 1.00 22.89 N ANISOU 1 N ARG A 192 2896 2874 2927 -6 -10 17 N ATOM 2 CA ARG A 192 -20.066 13.074 28.102 1.00 22.71 C ANISOU 2 CA ARG A 192 2875 2871 2881 0 -5 2 C ATOM 3 C ARG A 192 -20.363 12.329 26.821 1.00 22.55 C ANISOU 3 C ARG A 192 2842 2840 2885 -1 -16 13 C ATOM 4 O ARG A 192 -21.451 11.806 26.590 1.00 23.18 O ANISOU 4 O ARG A 192 2924 2894 2986 -24 -51 25 O ATOM 5 CB ARG A 192 -21.058 14.102 28.592 1.00 22.90 C ANISOU 5 CB ARG A 192 2889 2884 2928 0 -8 6 C ATOM 6 CG ARG A 192 -21.111 13.976 30.121 1.00 23.09 C ANISOU 6 CG ARG A 192 2914 2924 2933 -1 -4 6 C ATOM 7 CD ARG A 192 -21.432 15.240 30.842 1.00 23.41 C ANISOU 7 CD ARG A 192 2979 2958 2957 1 0 -8 C ATOM 8 NE ARG A 192 -22.826 15.623 30.679 1.00 23.52 N ANISOU 8 NE ARG A 192 2976 2981 2980 1 -1 0 N ATOM 9 CZ ARG A 192 -23.282 16.834 30.934 1.00 23.79 C ANISOU 9 CZ ARG A 192 3011 3011 3017 5 -4 1 C ATOM 10 NH1 ARG A 192 -22.446 17.766 31.357 1.00 24.31 N ANISOU 10 NH1 ARG A 192 3077 3077 3083 -5 -7 1 N ATOM 11 NH2 ARG A 192 -24.567 17.122 30.773 1.00 23.37 N ANISOU 11 NH2 ARG A 192 2959 2959 2958 -1 2 1 N ATOM 12 N LYS A 193 -19.360 12.353 25.968 1.00 21.80 N ANISOU 12 N LYS A 193 2773 2756 2753 1 -8 2 N ATOM 13 CA LYS A 193 -19.155 11.301 25.024 1.00 21.33 C ANISOU 13 CA LYS A 193 2691 2683 2729 2 -17 15 C ATOM 14 C LYS A 193 -18.545 10.141 25.836 1.00 20.74 C ANISOU 14 C LYS A 193 2607 2608 2664 -15 -6 20 C ATOM 15 O LYS A 193 -17.341 10.106 26.078 1.00 21.15 O ANISOU 15 O LYS A 193 2640 2649 2744 -14 -37 40 O ATOM 16 CB LYS A 193 -18.222 11.800 23.939 1.00 21.21 C ANISOU 16 CB LYS A 193 2704 2675 2680 7 -11 3 C ATOM 17 CG LYS A 193 -18.855 12.900 23.102 1.00 21.09 C ANISOU 17 CG LYS A 193 2699 2644 2668 5 -26 -14 C ATOM 18 CD LYS A 193 -19.263 12.389 21.738 1.00 20.30 C ANISOU 18 CD LYS A 193 2574 2561 2578 15 -17 27 C ATOM 19 CE LYS A 193 -20.269 13.305 21.088 1.00 19.49 C ANISOU 19 CE LYS A 193 2486 2490 2429 -14 1 10 C ATOM 20 NZ LYS A 193 -20.115 13.265 19.610 1.00 18.15 N ANISOU 20 NZ LYS A 193 2263 2312 2320 1 24 0 N ATOM 21 N SER A 194 -19.401 9.256 26.341 1.00 19.60 N ANISOU 21 N SER A 194 2482 2499 2464 12 7 2 N ATOM 22 CA SER A 194 -18.953 8.057 27.049 1.00 18.96 C ANISOU 22 CA SER A 194 2400 2422 2380 -2 6 -4 C ATOM 23 C SER A 194 -18.030 7.238 26.161 1.00 18.57 C ANISOU 23 C SER A 194 2345 2357 2353 2 -5 3 C ATOM 24 O SER A 194 -17.905 7.528 24.979 1.00 18.23 O ANISOU 24 O SER A 194 2298 2332 2297 9 -17 16 O ATOM 25 CB SER A 194 -20.151 7.182 27.409 1.00 19.00 C ANISOU 25 CB SER A 194 2411 2411 2395 1 -11 0 C ATOM 26 OG SER A 194 -20.447 6.280 26.354 1.00 18.70 O ANISOU 26 OG SER A 194 2357 2383 2364 -14 10 31 O ATOM 27 N LYS A 195 -17.420 6.192 26.722 1.00 18.28 N ANISOU 27 N LYS A 195 2311 2322 2312 -2 -10 -1 N ATOM 28 CA LYS A 195 -16.504 5.329 25.962 1.00 18.18 C ANISOU 28 CA LYS A 195 2317 2293 2298 4 -15 -3 C ATOM 29 C LYS A 195 -17.238 4.601 24.833 1.00 17.56 C ANISOU 29 C LYS A 195 2224 2216 2229 5 -11 8 C ATOM 30 O LYS A 195 -16.837 4.658 23.673 1.00 17.38 O ANISOU 30 O LYS A 195 2262 2169 2171 17 -53 -7 O ATOM 31 CB LYS A 195 -15.814 4.312 26.890 1.00 18.44 C ANISOU 31 CB LYS A 195 2349 2334 2321 4 -21 6 C ATOM 32 CG LYS A 195 -14.790 3.398 26.186 1.00 19.39 C ANISOU 32 CG LYS A 195 2447 2452 2467 5 21 -9 C ATOM 33 CD LYS A 195 -13.685 2.896 27.140 1.00 20.72 C ANISOU 33 CD LYS A 195 2583 2633 2657 15 -46 2 C ATOM 34 CE LYS A 195 -14.229 2.071 28.303 1.00 21.92 C ANISOU 34 CE LYS A 195 2778 2745 2805 -8 -2 14 C ATOM 35 NZ LYS A 195 -13.176 1.658 29.302 1.00 23.07 N ANISOU 35 NZ LYS A 195 2916 2885 2963 28 -85 6 N ATOM 36 N ALA A 196 -18.321 3.923 25.182 1.00 16.95 N ANISOU 36 N ALA A 196 2187 2138 2113 8 -26 -3 N ATOM 37 CA ALA A 196 -19.110 3.187 24.203 1.00 16.62 C ANISOU 37 CA ALA A 196 2123 2083 2107 9 -30 4 C ATOM 38 C ALA A 196 -19.581 4.081 23.046 1.00 15.82 C ANISOU 38 C ALA A 196 2026 1986 2000 5 -12 -12 C ATOM 39 O ALA A 196 -19.549 3.681 21.883 1.00 15.86 O ANISOU 39 O ALA A 196 2007 2016 2002 -8 -30 2 O ATOM 40 CB ALA A 196 -20.288 2.547 24.882 1.00 16.71 C ANISOU 40 CB ALA A 196 2131 2097 2117 13 -20 2 C ATOM 41 N GLU A 197 -20.032 5.288 23.365 1.00 15.08 N ANISOU 41 N GLU A 197 1911 1904 1911 -1 -42 15 N ATOM 42 CA GLU A 197 -20.500 6.208 22.331 1.00 14.22 C ANISOU 42 CA GLU A 197 1801 1803 1796 -9 -7 0 C ATOM 43 C GLU A 197 -19.379 6.739 21.455 1.00 13.08 C ANISOU 43 C GLU A 197 1677 1649 1643 3 -50 -11 C ATOM 44 O GLU A 197 -19.560 6.899 20.252 1.00 12.06 O ANISOU 44 O GLU A 197 1531 1577 1472 -3 39 9 O ATOM 45 CB GLU A 197 -21.264 7.362 22.960 1.00 14.67 C ANISOU 45 CB GLU A 197 1870 1851 1852 11 -17 -7 C ATOM 46 CG GLU A 197 -22.655 6.960 23.404 1.00 15.87 C ANISOU 46 CG GLU A 197 1986 2009 2034 -15 38 17 C ATOM 47 CD GLU A 197 -23.704 7.130 22.320 1.00 17.69 C ANISOU 47 CD GLU A 197 2241 2255 2223 -16 -48 35 C ATOM 48 OE1 GLU A 197 -23.455 6.716 21.173 1.00 19.81 O ANISOU 48 OE1 GLU A 197 2616 2442 2466 33 -38 -33 O ATOM 49 OE2 GLU A 197 -24.786 7.684 22.621 1.00 19.09 O ANISOU 49 OE2 GLU A 197 2329 2406 2517 -6 -52 23 O ATOM 50 N LEU A 198 -18.224 7.027 22.046 1.00 11.90 N ANISOU 50 N LEU A 198 1534 1501 1486 3 -3 11 N ATOM 51 CA LEU A 198 -17.109 7.517 21.264 1.00 11.21 C ANISOU 51 CA LEU A 198 1446 1413 1398 10 -28 -11 C ATOM 52 C LEU A 198 -16.710 6.414 20.294 1.00 10.85 C ANISOU 52 C LEU A 198 1387 1373 1361 3 -3 -2 C ATOM 53 O LEU A 198 -16.317 6.677 19.157 1.00 10.53 O ANISOU 53 O LEU A 198 1415 1299 1285 29 -58 -13 O ATOM 54 CB LEU A 198 -15.923 7.893 22.159 1.00 11.08 C ANISOU 54 CB LEU A 198 1427 1393 1390 1 -22 -5 C ATOM 55 CG LEU A 198 -16.001 9.276 22.827 1.00 10.86 C ANISOU 55 CG LEU A 198 1406 1377 1342 -4 -37 1 C ATOM 56 CD1 LEU A 198 -14.917 9.428 23.889 1.00 10.35 C ANISOU 56 CD1 LEU A 198 1325 1316 1290 8 -14 -25 C ATOM 57 CD2 LEU A 198 -15.895 10.395 21.801 1.00 10.62 C ANISOU 57 CD2 LEU A 198 1337 1313 1385 -19 -32 -9 C ATOM 58 N GLN A 199 -16.813 5.177 20.765 1.00 10.88 N ANISOU 58 N GLN A 199 1414 1363 1355 9 -31 -13 N ATOM 59 CA GLN A 199 -16.460 4.013 19.964 1.00 11.18 C ANISOU 59 CA GLN A 199 1441 1399 1405 12 -32 -6 C ATOM 60 C GLN A 199 -17.464 3.817 18.833 1.00 10.37 C ANISOU 60 C GLN A 199 1357 1288 1293 16 -23 -7 C ATOM 61 O GLN A 199 -17.072 3.643 17.676 1.00 10.16 O ANISOU 61 O GLN A 199 1306 1223 1331 63 -25 -28 O ATOM 62 CB GLN A 199 -16.412 2.761 20.842 1.00 11.77 C ANISOU 62 CB GLN A 199 1543 1452 1475 4 -12 0 C ATOM 63 CG GLN A 199 -15.172 2.689 21.730 1.00 13.74 C ANISOU 63 CG GLN A 199 1709 1800 1709 4 -49 -18 C ATOM 64 CD GLN A 199 -15.061 1.368 22.469 1.00 16.11 C ANISOU 64 CD GLN A 199 2058 2024 2038 0 -6 21 C ATOM 65 OE1 GLN A 199 -16.071 0.776 22.855 1.00 17.87 O ANISOU 65 OE1 GLN A 199 2164 2222 2402 7 -46 42 O ATOM 66 NE2 GLN A 199 -13.829 0.908 22.672 1.00 18.58 N ANISOU 66 NE2 GLN A 199 2336 2350 2372 24 -16 3 N ATOM 67 N SER A 200 -18.748 3.856 19.175 1.00 10.22 N ANISOU 67 N SER A 200 1349 1251 1280 18 -43 0 N ATOM 68 CA SER A 200 -19.818 3.671 18.195 1.00 10.00 C ANISOU 68 CA SER A 200 1316 1227 1255 16 -37 3 C ATOM 69 C SER A 200 -19.730 4.731 17.094 1.00 9.33 C ANISOU 69 C SER A 200 1252 1135 1156 16 -33 -7 C ATOM 70 O SER A 200 -19.831 4.414 15.895 1.00 9.05 O ANISOU 70 O SER A 200 1247 1033 1158 79 -136 -7 O ATOM 71 CB SER A 200 -21.192 3.699 18.876 1.00 10.40 C ANISOU 71 CB SER A 200 1369 1295 1287 15 -44 20 C ATOM 72 OG SER A 200 -21.390 4.893 19.612 1.00 11.84 O ANISOU 72 OG SER A 200 1553 1438 1504 74 -79 0 O ATOM 73 N GLU A 201 -19.497 5.979 17.498 1.00 8.66 N ANISOU 73 N GLU A 201 1149 1068 1073 9 -34 15 N ATOM 74 CA GLU A 201 -19.406 7.090 16.546 1.00 8.28 C ANISOU 74 CA GLU A 201 1097 1022 1025 0 -75 0 C ATOM 75 C GLU A 201 -18.214 6.951 15.617 1.00 8.07 C ANISOU 75 C GLU A 201 1111 971 981 14 -78 -6 C ATOM 76 O GLU A 201 -18.327 7.232 14.424 1.00 7.92 O ANISOU 76 O GLU A 201 1172 904 931 45 -97 10 O ATOM 77 CB GLU A 201 -19.392 8.447 17.274 1.00 8.16 C ANISOU 77 CB GLU A 201 1077 1015 1008 10 -70 1 C ATOM 78 CG GLU A 201 -20.720 8.772 17.935 1.00 8.59 C ANISOU 78 CG GLU A 201 1138 1053 1070 13 -66 -5 C ATOM 79 CD GLU A 201 -20.725 10.095 18.693 1.00 8.40 C ANISOU 79 CD GLU A 201 1128 1063 998 41 -62 0 C ATOM 80 OE1 GLU A 201 -19.861 10.957 18.450 1.00 10.68 O ANISOU 80 OE1 GLU A 201 1409 1229 1419 -99 -109 -9 O ATOM 81 OE2 GLU A 201 -21.601 10.280 19.529 1.00 8.29 O ANISOU 81 OE2 GLU A 201 1033 1068 1049 -35 -92 102 O ATOM 82 N GLU A 202 -17.064 6.528 16.150 1.00 7.75 N ANISOU 82 N GLU A 202 1039 962 944 13 -103 6 N ATOM 83 CA GLU A 202 -15.878 6.329 15.340 1.00 8.29 C ANISOU 83 CA GLU A 202 1101 1019 1027 15 -110 -14 C ATOM 84 C GLU A 202 -16.109 5.185 14.358 1.00 7.77 C ANISOU 84 C GLU A 202 988 968 994 43 -61 -6 C ATOM 85 O GLU A 202 -15.746 5.286 13.192 1.00 7.74 O ANISOU 85 O GLU A 202 1030 895 1016 44 -171 14 O ATOM 86 CB GLU A 202 -14.662 6.036 16.229 1.00 8.92 C ANISOU 86 CB GLU A 202 1137 1104 1147 0 -132 8 C ATOM 87 CG GLU A 202 -13.388 5.666 15.502 1.00 11.28 C ANISOU 87 CG GLU A 202 1432 1450 1403 63 -102 -40 C ATOM 88 CD GLU A 202 -12.618 6.859 14.980 1.00 14.51 C ANISOU 88 CD GLU A 202 1813 1788 1910 -66 -22 21 C ATOM 89 OE1 GLU A 202 -13.096 7.995 15.170 1.00 17.07 O ANISOU 89 OE1 GLU A 202 2171 1937 2376 13 -142 -18 O ATOM 90 OE2 GLU A 202 -11.530 6.654 14.379 1.00 16.80 O ANISOU 90 OE2 GLU A 202 2017 2150 2214 -25 57 12 O ATOM 91 N ARG A 203 -16.726 4.103 14.824 1.00 8.12 N ANISOU 91 N ARG A 203 1050 1015 1017 49 -81 -8 N ATOM 92 CA ARG A 203 -16.946 2.974 13.932 1.00 8.69 C ANISOU 92 CA ARG A 203 1153 1082 1067 36 -55 -25 C ATOM 93 C ARG A 203 -17.819 3.414 12.754 1.00 7.97 C ANISOU 93 C ARG A 203 1054 1004 970 36 -30 -4 C ATOM 94 O ARG A 203 -17.496 3.144 11.591 1.00 8.08 O ANISOU 94 O ARG A 203 1168 916 983 60 -52 -42 O ATOM 95 CB ARG A 203 -17.589 1.815 14.660 1.00 9.57 C ANISOU 95 CB ARG A 203 1222 1213 1198 56 -5 27 C ATOM 96 CG ARG A 203 -17.988 0.669 13.758 1.00 12.84 C ANISOU 96 CG ARG A 203 1698 1605 1574 1 -67 -103 C ATOM 97 CD ARG A 203 -18.240 -0.640 14.487 1.00 17.06 C ANISOU 97 CD ARG A 203 2310 2054 2117 -70 0 56 C ATOM 98 NE ARG A 203 -17.049 -1.489 14.507 1.00 20.36 N ANISOU 98 NE ARG A 203 2565 2586 2583 24 -9 -2 N ATOM 99 CZ ARG A 203 -17.062 -2.805 14.723 1.00 22.93 C ANISOU 99 CZ ARG A 203 2917 2885 2910 -4 -4 7 C ATOM 100 NH1 ARG A 203 -18.204 -3.440 14.935 1.00 23.95 N ANISOU 100 NH1 ARG A 203 3034 3029 3036 -6 3 5 N ATOM 101 NH2 ARG A 203 -15.924 -3.488 14.722 1.00 24.39 N ANISOU 101 NH2 ARG A 203 3085 3086 3094 18 -4 -4 N ATOM 102 N LYS A 204 -18.884 4.132 13.064 1.00 7.32 N ANISOU 102 N LYS A 204 1050 874 856 15 -50 -8 N ATOM 103 CA LYS A 204 -19.824 4.586 12.049 1.00 7.15 C ANISOU 103 CA LYS A 204 938 898 879 29 -22 -24 C ATOM 104 C LYS A 204 -19.163 5.538 11.053 1.00 6.78 C ANISOU 104 C LYS A 204 907 833 836 33 -35 -27 C ATOM 105 O LYS A 204 -19.383 5.446 9.834 1.00 5.97 O ANISOU 105 O LYS A 204 799 719 748 89 -9 -33 O ATOM 106 CB LYS A 204 -21.003 5.271 12.722 1.00 7.51 C ANISOU 106 CB LYS A 204 979 938 937 10 -14 -8 C ATOM 107 CG LYS A 204 -22.112 5.591 11.796 1.00 9.60 C ANISOU 107 CG LYS A 204 1249 1190 1208 1 -88 23 C ATOM 108 CD LYS A 204 -23.272 6.045 12.594 1.00 11.69 C ANISOU 108 CD LYS A 204 1497 1451 1493 17 28 5 C ATOM 109 CE LYS A 204 -24.555 5.971 11.824 1.00 13.13 C ANISOU 109 CE LYS A 204 1662 1640 1685 -1 -74 26 C ATOM 110 NZ LYS A 204 -25.652 6.385 12.707 1.00 15.32 N ANISOU 110 NZ LYS A 204 2042 1880 1898 63 48 27 N ATOM 111 N ARG A 205 -18.352 6.451 11.577 1.00 6.51 N ANISOU 111 N ARG A 205 835 826 811 47 -41 -42 N ATOM 112 CA ARG A 205 -17.650 7.427 10.768 1.00 7.18 C ANISOU 112 CA ARG A 205 958 894 873 21 -52 -7 C ATOM 113 C ARG A 205 -16.766 6.719 9.768 1.00 7.00 C ANISOU 113 C ARG A 205 884 889 887 -25 -67 0 C ATOM 114 O ARG A 205 -16.744 7.063 8.590 1.00 6.89 O ANISOU 114 O ARG A 205 960 879 776 34 -85 32 O ATOM 115 CB ARG A 205 -16.823 8.362 11.657 1.00 8.03 C ANISOU 115 CB ARG A 205 1013 988 1046 19 -78 1 C ATOM 116 CG ARG A 205 -16.052 9.425 10.929 1.00 9.53 C ANISOU 116 CG ARG A 205 1274 1207 1137 1 9 39 C ATOM 117 CD ARG A 205 -15.552 10.541 11.811 1.00 12.40 C ANISOU 117 CD ARG A 205 1627 1510 1575 -65 -41 -31 C ATOM 118 NE ARG A 205 -15.026 10.042 13.076 1.00 13.59 N ANISOU 118 NE ARG A 205 1759 1703 1698 -9 -78 37 N ATOM 119 CZ ARG A 205 -15.625 10.173 14.257 1.00 14.22 C ANISOU 119 CZ ARG A 205 1782 1814 1805 -62 14 15 C ATOM 120 NH1 ARG A 205 -16.800 10.789 14.376 1.00 15.60 N ANISOU 120 NH1 ARG A 205 1970 1936 2021 20 -37 28 N ATOM 121 NH2 ARG A 205 -15.044 9.675 15.337 1.00 14.86 N ANISOU 121 NH2 ARG A 205 1878 1810 1956 -87 -94 51 N ATOM 122 N ILE A 206 -16.006 5.735 10.241 1.00 7.18 N ANISOU 122 N ILE A 206 951 865 911 -5 -65 -9 N ATOM 123 CA ILE A 206 -15.092 5.025 9.367 1.00 7.77 C ANISOU 123 CA ILE A 206 989 965 997 16 -36 -28 C ATOM 124 C ILE A 206 -15.858 4.180 8.356 1.00 6.81 C ANISOU 124 C ILE A 206 859 859 866 40 -20 -16 C ATOM 125 O ILE A 206 -15.523 4.154 7.166 1.00 6.16 O ANISOU 125 O ILE A 206 743 762 833 16 3 6 O ATOM 126 CB ILE A 206 -14.133 4.163 10.191 1.00 8.51 C ANISOU 126 CB ILE A 206 1104 1034 1092 36 -61 -9 C ATOM 127 CG1 ILE A 206 -13.218 5.066 11.032 1.00 11.13 C ANISOU 127 CG1 ILE A 206 1432 1348 1447 -23 -118 -90 C ATOM 128 CG2 ILE A 206 -13.304 3.280 9.273 1.00 8.87 C ANISOU 128 CG2 ILE A 206 1132 1105 1131 -25 45 37 C ATOM 129 CD1 ILE A 206 -12.169 4.310 11.802 1.00 13.13 C ANISOU 129 CD1 ILE A 206 1693 1618 1676 26 -118 6 C ATOM 130 N ASP A 207 -16.879 3.479 8.825 1.00 7.20 N ANISOU 130 N ASP A 207 932 888 915 38 -22 -5 N ATOM 131 CA ASP A 207 -17.686 2.658 7.930 1.00 7.98 C ANISOU 131 CA ASP A 207 1045 990 994 17 -38 -23 C ATOM 132 C ASP A 207 -18.244 3.516 6.789 1.00 7.78 C ANISOU 132 C ASP A 207 1001 988 967 7 -27 -8 C ATOM 133 O ASP A 207 -18.239 3.090 5.640 1.00 7.06 O ANISOU 133 O ASP A 207 908 891 883 10 35 -67 O ATOM 134 CB ASP A 207 -18.883 2.023 8.630 1.00 8.73 C ANISOU 134 CB ASP A 207 1084 1100 1133 -35 -8 -36 C ATOM 135 CG ASP A 207 -18.514 1.069 9.762 1.00 12.32 C ANISOU 135 CG ASP A 207 1618 1503 1560 -2 -80 30 C ATOM 136 OD1 ASP A 207 -17.382 0.554 9.820 1.00 16.46 O ANISOU 136 OD1 ASP A 207 2100 1957 2194 189 -143 -15 O ATOM 137 OD2 ASP A 207 -19.362 0.760 10.638 1.00 17.80 O ANISOU 137 OD2 ASP A 207 2371 2261 2131 36 123 115 O ATOM 138 N GLU A 208 -18.752 4.706 7.121 1.00 7.98 N ANISOU 138 N GLU A 208 1034 1020 976 5 2 -19 N ATOM 139 CA GLU A 208 -19.356 5.587 6.119 1.00 8.70 C ANISOU 139 CA GLU A 208 1095 1104 1107 16 -35 -10 C ATOM 140 C GLU A 208 -18.343 6.044 5.086 1.00 9.06 C ANISOU 140 C GLU A 208 1229 1103 1108 22 -33 6 C ATOM 141 O GLU A 208 -18.659 6.101 3.896 1.00 8.91 O ANISOU 141 O GLU A 208 1263 1048 1071 73 -91 15 O ATOM 142 CB GLU A 208 -20.084 6.767 6.784 1.00 9.37 C ANISOU 142 CB GLU A 208 1248 1153 1156 34 -68 -31 C ATOM 143 CG GLU A 208 -21.348 6.289 7.492 1.00 12.14 C ANISOU 143 CG GLU A 208 1592 1560 1459 -51 -13 47 C ATOM 144 CD GLU A 208 -22.215 7.386 8.094 1.00 15.49 C ANISOU 144 CD GLU A 208 1991 1940 1955 108 25 23 C ATOM 145 OE1 GLU A 208 -21.671 8.428 8.532 1.00 19.89 O ANISOU 145 OE1 GLU A 208 2807 2303 2444 -23 -116 -72 O ATOM 146 OE2 GLU A 208 -23.446 7.187 8.145 1.00 17.71 O ANISOU 146 OE2 GLU A 208 2193 2283 2250 -16 2 29 O ATOM 147 N LEU A 209 -17.121 6.332 5.526 1.00 9.08 N ANISOU 147 N LEU A 209 1186 1106 1156 73 -13 14 N ATOM 148 CA LEU A 209 -16.070 6.729 4.610 1.00 9.93 C ANISOU 148 CA LEU A 209 1298 1212 1264 18 1 40 C ATOM 149 C LEU A 209 -15.679 5.587 3.677 1.00 9.88 C ANISOU 149 C LEU A 209 1315 1231 1204 17 35 24 C ATOM 150 O LEU A 209 -15.474 5.785 2.476 1.00 11.22 O ANISOU 150 O LEU A 209 1651 1323 1286 9 10 71 O ATOM 151 CB LEU A 209 -14.845 7.203 5.382 1.00 10.37 C ANISOU 151 CB LEU A 209 1246 1319 1372 -14 59 16 C ATOM 152 CG LEU A 209 -15.076 8.598 5.957 1.00 12.82 C ANISOU 152 CG LEU A 209 1659 1530 1683 -13 47 -23 C ATOM 153 CD1 LEU A 209 -14.121 8.925 7.073 1.00 13.85 C ANISOU 153 CD1 LEU A 209 1658 1750 1854 23 -2 -55 C ATOM 154 CD2 LEU A 209 -14.998 9.631 4.826 1.00 14.26 C ANISOU 154 CD2 LEU A 209 1867 1745 1804 -5 0 40 C ATOM 155 N ILE A 210 -15.543 4.387 4.228 1.00 9.62 N ANISOU 155 N ILE A 210 1299 1188 1167 28 75 23 N ATOM 156 CA ILE A 210 -15.168 3.245 3.415 1.00 9.49 C ANISOU 156 CA ILE A 210 1244 1193 1166 4 23 17 C ATOM 157 C ILE A 210 -16.240 2.998 2.369 1.00 9.85 C ANISOU 157 C ILE A 210 1308 1251 1184 9 5 -6 C ATOM 158 O ILE A 210 -15.931 2.838 1.188 1.00 11.10 O ANISOU 158 O ILE A 210 1475 1412 1327 119 73 38 O ATOM 159 CB ILE A 210 -14.962 1.986 4.293 1.00 9.34 C ANISOU 159 CB ILE A 210 1244 1167 1135 33 -10 -10 C ATOM 160 CG1 ILE A 210 -13.679 2.117 5.116 1.00 8.88 C ANISOU 160 CG1 ILE A 210 1126 1124 1125 -33 59 25 C ATOM 161 CG2 ILE A 210 -14.945 0.715 3.436 1.00 9.49 C ANISOU 161 CG2 ILE A 210 1224 1164 1216 6 4 -15 C ATOM 162 CD1 ILE A 210 -13.600 1.120 6.244 1.00 9.18 C ANISOU 162 CD1 ILE A 210 1145 1116 1226 10 -45 46 C ATOM 163 N GLU A 211 -17.497 3.003 2.810 1.00 10.00 N ANISOU 163 N GLU A 211 1300 1297 1202 11 -34 -19 N ATOM 164 CA GLU A 211 -18.635 2.675 1.963 1.00 11.00 C ANISOU 164 CA GLU A 211 1413 1420 1346 13 -32 -19 C ATOM 165 C GLU A 211 -18.867 3.696 0.860 1.00 11.53 C ANISOU 165 C GLU A 211 1492 1484 1404 0 -29 1 C ATOM 166 O GLU A 211 -19.206 3.320 -0.271 1.00 12.49 O ANISOU 166 O GLU A 211 1725 1608 1412 31 -44 11 O ATOM 167 CB GLU A 211 -19.880 2.500 2.832 1.00 11.18 C ANISOU 167 CB GLU A 211 1391 1478 1379 -20 -64 -32 C ATOM 168 CG GLU A 211 -19.770 1.255 3.705 1.00 13.51 C ANISOU 168 CG GLU A 211 1791 1619 1720 19 -89 30 C ATOM 169 CD GLU A 211 -20.811 1.143 4.805 1.00 16.12 C ANISOU 169 CD GLU A 211 2014 2094 2014 1 14 17 C ATOM 170 OE1 GLU A 211 -21.633 2.065 5.002 1.00 18.35 O ANISOU 170 OE1 GLU A 211 2431 2201 2337 131 -2 3 O ATOM 171 OE2 GLU A 211 -20.813 0.099 5.493 1.00 18.61 O ANISOU 171 OE2 GLU A 211 2475 2204 2391 43 -76 92 O ATOM 172 N SER A 212 -18.687 4.974 1.170 1.00 12.10 N ANISOU 172 N SER A 212 1522 1561 1513 22 6 3 N ATOM 173 CA SER A 212 -18.896 6.032 0.180 1.00 13.05 C ANISOU 173 CA SER A 212 1676 1662 1618 11 -25 16 C ATOM 174 C SER A 212 -17.794 6.048 -0.875 1.00 13.85 C ANISOU 174 C SER A 212 1794 1775 1692 13 -6 12 C ATOM 175 O SER A 212 -18.006 6.476 -2.011 1.00 14.22 O ANISOU 175 O SER A 212 1913 1796 1691 37 -26 48 O ATOM 176 CB SER A 212 -18.931 7.395 0.866 1.00 13.17 C ANISOU 176 CB SER A 212 1701 1651 1649 46 8 29 C ATOM 177 OG SER A 212 -17.635 7.771 1.281 1.00 14.44 O ANISOU 177 OG SER A 212 1937 1723 1824 6 29 0 O ATOM 178 N GLY A 213 -16.610 5.588 -0.487 1.00 14.56 N ANISOU 178 N GLY A 213 1842 1879 1809 13 -12 13 N ATOM 179 CA GLY A 213 -15.460 5.603 -1.365 1.00 15.33 C ANISOU 179 CA GLY A 213 1960 1950 1914 16 27 12 C ATOM 180 C GLY A 213 -15.001 7.011 -1.710 1.00 16.03 C ANISOU 180 C GLY A 213 2036 2025 2029 -16 24 -20 C ATOM 181 O GLY A 213 -14.265 7.192 -2.674 1.00 16.63 O ANISOU 181 O GLY A 213 2191 2050 2078 -46 72 10 O ATOM 182 N LYS A 214 -15.442 8.015 -0.957 1.00 16.39 N ANISOU 182 N LYS A 214 2083 2070 2071 12 1 -30 N ATOM 183 CA LYS A 214 -14.982 9.369 -1.209 1.00 16.98 C ANISOU 183 CA LYS A 214 2145 2148 2158 -11 8 -15 C ATOM 184 C LYS A 214 -13.502 9.431 -0.819 1.00 16.72 C ANISOU 184 C LYS A 214 2141 2101 2108 -2 -6 -3 C ATOM 185 O LYS A 214 -13.094 9.042 0.294 1.00 17.43 O ANISOU 185 O LYS A 214 2281 2161 2178 -60 25 1 O ATOM 186 CB LYS A 214 -15.808 10.411 -0.446 1.00 17.82 C ANISOU 186 CB LYS A 214 2283 2231 2256 -14 15 -42 C ATOM 187 CG LYS A 214 -17.188 10.659 -1.019 1.00 19.63 C ANISOU 187 CG LYS A 214 2455 2492 2508 -11 -3 -11 C ATOM 188 CD LYS A 214 -17.151 11.433 -2.342 1.00 22.23 C ANISOU 188 CD LYS A 214 2906 2800 2739 -25 10 44 C ATOM 189 CE LYS A 214 -18.547 11.805 -2.810 1.00 23.60 C ANISOU 189 CE LYS A 214 2985 2989 2992 -7 0 7 C ATOM 190 NZ LYS A 214 -19.231 12.785 -1.908 1.00 24.97 N ANISOU 190 NZ LYS A 214 3168 3155 3161 5 17 -14 N ATOM 191 N GLU A 215 -12.701 9.896 -1.763 1.00 16.05 N ANISOU 191 N GLU A 215 2052 2011 2035 17 27 -19 N ATOM 192 CA GLU A 215 -11.271 9.980 -1.581 1.00 15.37 C ANISOU 192 CA GLU A 215 1973 1929 1936 2 38 -18 C ATOM 193 C GLU A 215 -10.870 11.433 -1.717 1.00 15.15 C ANISOU 193 C GLU A 215 1958 1896 1901 31 57 17 C ATOM 194 O GLU A 215 -10.143 11.818 -2.624 1.00 16.75 O ANISOU 194 O GLU A 215 2141 2091 2132 32 151 43 O ATOM 195 CB GLU A 215 -10.560 9.036 -2.563 1.00 14.88 C ANISOU 195 CB GLU A 215 1906 1885 1862 -1 17 -4 C ATOM 196 CG GLU A 215 -10.989 7.598 -2.313 1.00 13.85 C ANISOU 196 CG GLU A 215 1756 1795 1708 50 40 9 C ATOM 197 CD GLU A 215 -10.141 6.529 -2.983 1.00 13.81 C ANISOU 197 CD GLU A 215 1722 1755 1769 25 55 57 C ATOM 198 OE1 GLU A 215 -9.465 6.847 -3.988 1.00 12.62 O ANISOU 198 OE1 GLU A 215 1435 1712 1645 75 119 -64 O ATOM 199 OE2 GLU A 215 -10.212 5.352 -2.509 1.00 13.13 O ANISOU 199 OE2 GLU A 215 1709 1727 1553 90 -51 -11 O ATOM 200 N GLU A 216 -11.348 12.234 -0.770 1.00 14.43 N ANISOU 200 N GLU A 216 1799 1832 1851 -3 47 24 N ATOM 201 CA GLU A 216 -11.159 13.673 -0.789 1.00 13.78 C ANISOU 201 CA GLU A 216 1702 1772 1762 -9 18 0 C ATOM 202 C GLU A 216 -9.849 14.094 -0.133 1.00 12.40 C ANISOU 202 C GLU A 216 1560 1584 1565 5 15 12 C ATOM 203 O GLU A 216 -9.295 13.366 0.694 1.00 12.78 O ANISOU 203 O GLU A 216 1559 1677 1620 -28 8 41 O ATOM 204 CB GLU A 216 -12.316 14.349 -0.055 1.00 14.90 C ANISOU 204 CB GLU A 216 1892 1856 1911 41 42 17 C ATOM 205 CG GLU A 216 -13.684 13.968 -0.604 1.00 17.60 C ANISOU 205 CG GLU A 216 2206 2237 2243 -97 -36 19 C ATOM 206 CD GLU A 216 -14.811 14.737 0.046 1.00 21.20 C ANISOU 206 CD GLU A 216 2662 2651 2739 36 78 -8 C ATOM 207 OE1 GLU A 216 -14.715 15.008 1.273 1.00 24.33 O ANISOU 207 OE1 GLU A 216 3238 3091 2914 -61 51 -47 O ATOM 208 OE2 GLU A 216 -15.785 15.073 -0.665 1.00 22.62 O ANISOU 208 OE2 GLU A 216 2816 2887 2888 3 -36 -7 O ATOM 209 N GLY A 217 -9.360 15.260 -0.536 1.00 10.59 N ANISOU 209 N GLY A 217 1288 1406 1328 26 20 -32 N ATOM 210 CA GLY A 217 -8.172 15.855 0.053 1.00 9.63 C ANISOU 210 CA GLY A 217 1206 1239 1215 -18 38 -11 C ATOM 211 C GLY A 217 -6.865 15.291 -0.457 1.00 9.00 C ANISOU 211 C GLY A 217 1108 1178 1134 -26 -5 -16 C ATOM 212 O GLY A 217 -5.820 15.429 0.200 1.00 8.38 O ANISOU 212 O GLY A 217 932 1166 1083 -72 47 -30 O ATOM 213 N MET A 218 -6.917 14.677 -1.634 1.00 8.55 N ANISOU 213 N MET A 218 1061 1141 1045 -17 0 -14 N ATOM 214 CA MET A 218 -5.744 14.026 -2.208 1.00 8.84 C ANISOU 214 CA MET A 218 1097 1181 1078 7 9 -14 C ATOM 215 C MET A 218 -5.639 14.230 -3.696 1.00 8.66 C ANISOU 215 C MET A 218 1064 1168 1058 29 6 -19 C ATOM 216 O MET A 218 -6.655 14.304 -4.374 1.00 9.28 O ANISOU 216 O MET A 218 1050 1387 1089 32 -11 -16 O ATOM 217 CB MET A 218 -5.802 12.521 -1.976 1.00 9.71 C ANISOU 217 CB MET A 218 1195 1242 1251 52 23 -1 C ATOM 218 CG MET A 218 -5.688 12.097 -0.545 1.00 11.29 C ANISOU 218 CG MET A 218 1443 1527 1317 -5 18 -27 C ATOM 219 SD MET A 218 -5.966 10.325 -0.414 1.00 13.83 S ANISOU 219 SD MET A 218 1590 1726 1937 -14 93 254 S ATOM 220 CE MET A 218 -7.700 10.208 -0.604 1.00 14.43 C ANISOU 220 CE MET A 218 1712 1888 1880 -20 -77 95 C ATOM 221 N LYS A 219 -4.407 14.322 -4.191 1.00 8.11 N ANISOU 221 N LYS A 219 965 1102 1012 26 1 -61 N ATOM 222 CA LYS A 219 -4.183 14.369 -5.637 1.00 8.28 C ANISOU 222 CA LYS A 219 992 1108 1043 24 5 -57 C ATOM 223 C LYS A 219 -2.968 13.533 -6.018 1.00 7.73 C ANISOU 223 C LYS A 219 973 1036 925 45 -19 -45 C ATOM 224 O LYS A 219 -2.068 13.333 -5.221 1.00 7.32 O ANISOU 224 O LYS A 219 849 1021 910 127 -19 -166 O ATOM 225 CB LYS A 219 -3.981 15.814 -6.114 1.00 8.99 C ANISOU 225 CB LYS A 219 1126 1149 1141 75 39 -2 C ATOM 226 CG LYS A 219 -4.291 16.050 -7.562 1.00 13.50 C ANISOU 226 CG LYS A 219 1716 1794 1620 34 15 -10 C ATOM 227 CD LYS A 219 -4.026 17.504 -7.927 1.00 17.51 C ANISOU 227 CD LYS A 219 2318 2041 2295 -32 24 27 C ATOM 228 CE LYS A 219 -4.712 17.905 -9.210 1.00 19.72 C ANISOU 228 CE LYS A 219 2501 2536 2456 20 -32 52 C ATOM 229 NZ LYS A 219 -4.529 19.369 -9.487 1.00 21.82 N ANISOU 229 NZ LYS A 219 2845 2577 2867 -23 38 -16 N ATOM 230 N ILE A 220 -2.943 13.077 -7.267 1.00 7.68 N ANISOU 230 N ILE A 220 951 1059 905 5 -29 -80 N ATOM 231 CA ILE A 220 -1.808 12.327 -7.798 1.00 8.33 C ANISOU 231 CA ILE A 220 1038 1089 1036 43 -43 -33 C ATOM 232 C ILE A 220 -0.752 13.313 -8.312 1.00 8.94 C ANISOU 232 C ILE A 220 1106 1170 1117 24 -8 9 C ATOM 233 O ILE A 220 -1.095 14.374 -8.822 1.00 9.87 O ANISOU 233 O ILE A 220 1105 1302 1342 91 28 81 O ATOM 234 CB ILE A 220 -2.277 11.381 -8.937 1.00 8.63 C ANISOU 234 CB ILE A 220 1095 1125 1058 34 -18 -26 C ATOM 235 CG1 ILE A 220 -3.312 10.402 -8.381 1.00 9.32 C ANISOU 235 CG1 ILE A 220 1167 1154 1219 0 -20 -104 C ATOM 236 CG2 ILE A 220 -1.081 10.636 -9.512 1.00 9.67 C ANISOU 236 CG2 ILE A 220 1289 1218 1164 55 29 -45 C ATOM 237 CD1 ILE A 220 -4.084 9.653 -9.431 1.00 10.67 C ANISOU 237 CD1 ILE A 220 1390 1307 1354 -33 -35 -133 C ATOM 238 N ASP A 221 0.530 12.991 -8.123 1.00 9.45 N ANISOU 238 N ASP A 221 1146 1232 1209 60 -28 24 N ATOM 239 CA ASP A 221 1.638 13.779 -8.683 1.00 9.89 C ANISOU 239 CA ASP A 221 1227 1273 1256 32 2 34 C ATOM 240 C ASP A 221 2.777 12.845 -9.060 1.00 8.90 C ANISOU 240 C ASP A 221 1116 1128 1137 2 5 23 C ATOM 241 O ASP A 221 2.814 11.711 -8.603 1.00 9.33 O ANISOU 241 O ASP A 221 1118 1272 1155 1 128 162 O ATOM 242 CB ASP A 221 2.162 14.808 -7.681 1.00 11.35 C ANISOU 242 CB ASP A 221 1437 1424 1450 40 -4 -20 C ATOM 243 CG ASP A 221 3.110 15.814 -8.307 1.00 15.33 C ANISOU 243 CG ASP A 221 1887 1890 2044 -22 85 41 C ATOM 244 OD1 ASP A 221 3.017 16.075 -9.526 1.00 19.60 O ANISOU 244 OD1 ASP A 221 2588 2473 2383 49 -53 17 O ATOM 245 OD2 ASP A 221 3.998 16.404 -7.645 1.00 20.59 O ANISOU 245 OD2 ASP A 221 2559 2606 2657 -119 -113 -142 O ATOM 246 N LEU A 222 3.696 13.304 -9.905 1.00 7.71 N ANISOU 246 N LEU A 222 949 1010 971 7 -14 59 N ATOM 247 CA LEU A 222 4.902 12.527 -10.201 1.00 7.51 C ANISOU 247 CA LEU A 222 975 926 951 -6 -13 14 C ATOM 248 C LEU A 222 5.893 12.914 -9.118 1.00 7.39 C ANISOU 248 C LEU A 222 965 907 935 10 -53 -1 C ATOM 249 O LEU A 222 6.142 14.116 -8.898 1.00 7.84 O ANISOU 249 O LEU A 222 1005 911 1060 38 -145 14 O ATOM 250 CB LEU A 222 5.484 12.851 -11.582 1.00 7.71 C ANISOU 250 CB LEU A 222 960 997 970 -17 -7 -18 C ATOM 251 CG LEU A 222 4.569 12.511 -12.756 1.00 8.36 C ANISOU 251 CG LEU A 222 990 1092 1092 30 -29 0 C ATOM 252 CD1 LEU A 222 5.278 12.866 -14.050 1.00 9.88 C ANISOU 252 CD1 LEU A 222 1303 1307 1143 46 -9 -37 C ATOM 253 CD2 LEU A 222 4.179 11.037 -12.712 1.00 7.95 C ANISOU 253 CD2 LEU A 222 987 1116 917 33 -74 -38 C ATOM 254 N ILE A 223 6.473 11.905 -8.465 1.00 6.90 N ANISOU 254 N ILE A 223 855 881 884 -23 -83 -19 N ATOM 255 CA ILE A 223 7.370 12.111 -7.322 1.00 6.75 C ANISOU 255 CA ILE A 223 876 873 813 3 -41 -48 C ATOM 256 C ILE A 223 8.760 11.619 -7.692 1.00 5.83 C ANISOU 256 C ILE A 223 758 758 696 -51 -52 -35 C ATOM 257 O ILE A 223 8.930 10.493 -8.154 1.00 5.88 O ANISOU 257 O ILE A 223 766 753 712 18 -101 -56 O ATOM 258 CB ILE A 223 6.862 11.294 -6.117 1.00 7.73 C ANISOU 258 CB ILE A 223 981 1025 930 39 13 -21 C ATOM 259 CG1 ILE A 223 5.419 11.671 -5.750 1.00 9.41 C ANISOU 259 CG1 ILE A 223 1096 1296 1181 7 37 41 C ATOM 260 CG2 ILE A 223 7.827 11.399 -4.954 1.00 8.38 C ANISOU 260 CG2 ILE A 223 1120 1068 995 33 22 37 C ATOM 261 CD1 ILE A 223 5.227 13.083 -5.288 1.00 11.00 C ANISOU 261 CD1 ILE A 223 1402 1386 1392 78 -11 -43 C ATOM 262 N ASP A 224 9.757 12.460 -7.489 1.00 5.29 N ANISOU 262 N ASP A 224 707 717 584 -35 -65 -39 N ATOM 263 CA ASP A 224 11.120 12.132 -7.854 1.00 4.92 C ANISOU 263 CA ASP A 224 642 674 553 -37 -34 -5 C ATOM 264 C ASP A 224 11.549 10.790 -7.281 1.00 4.70 C ANISOU 264 C ASP A 224 591 636 556 -14 -15 -35 C ATOM 265 O ASP A 224 11.484 10.581 -6.069 1.00 6.31 O ANISOU 265 O ASP A 224 923 886 586 97 -27 24 O ATOM 266 CB ASP A 224 12.044 13.254 -7.334 1.00 5.20 C ANISOU 266 CB ASP A 224 735 633 607 -12 -114 -62 C ATOM 267 CG ASP A 224 13.401 13.272 -7.994 1.00 7.07 C ANISOU 267 CG ASP A 224 932 897 856 0 -13 -22 C ATOM 268 OD1 ASP A 224 13.623 12.562 -8.995 1.00 7.80 O ANISOU 268 OD1 ASP A 224 1012 1159 791 104 -114 -193 O ATOM 269 OD2 ASP A 224 14.343 13.999 -7.588 1.00 9.81 O ANISOU 269 OD2 ASP A 224 1293 1171 1260 -51 -251 -218 O ATOM 270 N GLY A 225 11.976 9.875 -8.143 1.00 4.36 N ANISOU 270 N GLY A 225 568 648 441 -35 -56 -46 N ATOM 271 CA GLY A 225 12.469 8.573 -7.735 1.00 4.73 C ANISOU 271 CA GLY A 225 605 695 496 22 -32 -28 C ATOM 272 C GLY A 225 11.444 7.530 -7.372 1.00 5.48 C ANISOU 272 C GLY A 225 713 699 669 23 -12 18 C ATOM 273 O GLY A 225 11.801 6.395 -7.006 1.00 7.35 O ANISOU 273 O GLY A 225 884 915 992 48 -33 90 O ATOM 274 N LYS A 226 10.163 7.874 -7.479 1.00 5.14 N ANISOU 274 N LYS A 226 638 695 618 14 -15 23 N ATOM 275 CA LYS A 226 9.117 6.955 -7.009 1.00 5.83 C ANISOU 275 CA LYS A 226 711 748 755 -6 17 11 C ATOM 276 C LYS A 226 8.022 6.640 -8.008 1.00 6.62 C ANISOU 276 C LYS A 226 812 852 852 -3 -23 50 C ATOM 277 O LYS A 226 7.232 5.736 -7.761 1.00 8.85 O ANISOU 277 O LYS A 226 1017 1159 1185 -94 -144 117 O ATOM 278 CB LYS A 226 8.462 7.491 -5.724 1.00 5.84 C ANISOU 278 CB LYS A 226 793 636 788 4 27 19 C ATOM 279 CG LYS A 226 9.440 7.843 -4.622 1.00 8.04 C ANISOU 279 CG LYS A 226 1055 1036 963 18 19 17 C ATOM 280 CD LYS A 226 8.693 8.203 -3.330 1.00 9.81 C ANISOU 280 CD LYS A 226 1305 1188 1234 46 178 31 C ATOM 281 CE LYS A 226 9.602 8.814 -2.306 1.00 12.41 C ANISOU 281 CE LYS A 226 1690 1567 1459 93 -18 29 C ATOM 282 NZ LYS A 226 8.882 9.405 -1.135 1.00 15.54 N ANISOU 282 NZ LYS A 226 1975 2159 1768 229 80 -46 N ATOM 283 N GLY A 227 7.948 7.362 -9.122 1.00 6.45 N ANISOU 283 N GLY A 227 791 890 769 -9 3 -8 N ATOM 284 CA GLY A 227 6.813 7.186 -10.014 1.00 6.49 C ANISOU 284 CA GLY A 227 773 875 814 56 -10 -2 C ATOM 285 C GLY A 227 5.691 8.124 -9.613 1.00 6.49 C ANISOU 285 C GLY A 227 805 847 813 14 -46 -32 C ATOM 286 O GLY A 227 5.936 9.295 -9.334 1.00 8.36 O ANISOU 286 O GLY A 227 956 979 1239 44 -129 -46 O ATOM 287 N ARG A 228 4.457 7.627 -9.623 1.00 5.45 N ANISOU 287 N ARG A 228 681 749 639 -3 -32 -35 N ATOM 288 CA ARG A 228 3.339 8.411 -9.144 1.00 5.89 C ANISOU 288 CA ARG A 228 754 814 670 32 -34 -7 C ATOM 289 C ARG A 228 3.325 8.327 -7.616 1.00 5.68 C ANISOU 289 C ARG A 228 741 773 641 52 -11 -22 C ATOM 290 O ARG A 228 3.792 7.341 -7.015 1.00 5.45 O ANISOU 290 O ARG A 228 772 793 502 57 16 -28 O ATOM 291 CB ARG A 228 2.005 7.856 -9.638 1.00 6.62 C ANISOU 291 CB ARG A 228 788 935 791 50 -59 -25 C ATOM 292 CG ARG A 228 1.823 7.851 -11.146 1.00 8.06 C ANISOU 292 CG ARG A 228 1031 1143 889 86 34 -21 C ATOM 293 CD ARG A 228 0.671 6.955 -11.622 1.00 9.04 C ANISOU 293 CD ARG A 228 1134 1293 1004 18 4 -1 C ATOM 294 NE ARG A 228 0.941 5.522 -11.471 1.00 10.79 N ANISOU 294 NE ARG A 228 1407 1394 1299 -53 -94 -90 N ATOM 295 CZ ARG A 228 0.098 4.549 -11.835 1.00 9.61 C ANISOU 295 CZ ARG A 228 1179 1291 1179 -47 62 35 C ATOM 296 NH1 ARG A 228 -1.093 4.851 -12.328 1.00 9.78 N ANISOU 296 NH1 ARG A 228 1244 1398 1073 12 0 18 N ATOM 297 NH2 ARG A 228 0.430 3.276 -11.666 1.00 11.05 N ANISOU 297 NH2 ARG A 228 1441 1372 1386 -33 -69 -113 N ATOM 298 N GLY A 229 2.761 9.354 -7.004 1.00 5.78 N ANISOU 298 N GLY A 229 737 763 696 43 -6 -47 N ATOM 299 CA GLY A 229 2.538 9.351 -5.575 1.00 5.76 C ANISOU 299 CA GLY A 229 691 781 715 42 5 -59 C ATOM 300 C GLY A 229 1.294 10.168 -5.289 1.00 5.59 C ANISOU 300 C GLY A 229 652 765 707 39 -9 10 C ATOM 301 O GLY A 229 0.688 10.711 -6.194 1.00 7.14 O ANISOU 301 O GLY A 229 864 987 862 164 37 -19 O ATOM 302 N VAL A 230 0.894 10.228 -4.033 1.00 5.85 N ANISOU 302 N VAL A 230 676 821 725 88 -20 -12 N ATOM 303 CA VAL A 230 -0.320 10.971 -3.659 1.00 6.00 C ANISOU 303 CA VAL A 230 753 806 719 62 5 -25 C ATOM 304 C VAL A 230 0.052 12.092 -2.689 1.00 6.06 C ANISOU 304 C VAL A 230 727 823 751 19 -35 -9 C ATOM 305 O VAL A 230 0.794 11.863 -1.737 1.00 6.06 O ANISOU 305 O VAL A 230 838 762 701 70 -79 -90 O ATOM 306 CB VAL A 230 -1.354 10.046 -3.025 1.00 6.47 C ANISOU 306 CB VAL A 230 807 867 784 24 -20 28 C ATOM 307 CG1 VAL A 230 -2.602 10.804 -2.674 1.00 8.33 C ANISOU 307 CG1 VAL A 230 1020 1023 1118 78 32 -3 C ATOM 308 CG2 VAL A 230 -1.692 8.890 -3.946 1.00 7.07 C ANISOU 308 CG2 VAL A 230 892 888 906 41 25 37 C ATOM 309 N ILE A 231 -0.442 13.292 -2.971 1.00 5.84 N ANISOU 309 N ILE A 231 701 752 764 4 17 -72 N ATOM 310 CA ILE A 231 -0.152 14.461 -2.162 1.00 6.91 C ANISOU 310 CA ILE A 231 877 871 875 32 0 -50 C ATOM 311 C ILE A 231 -1.427 14.921 -1.510 1.00 6.29 C ANISOU 311 C ILE A 231 800 816 772 -20 -19 -58 C ATOM 312 O ILE A 231 -2.515 14.862 -2.087 1.00 6.53 O ANISOU 312 O ILE A 231 815 900 766 74 -53 -81 O ATOM 313 CB ILE A 231 0.445 15.583 -3.060 1.00 7.96 C ANISOU 313 CB ILE A 231 994 938 1089 -68 -15 -73 C ATOM 314 CG1 ILE A 231 1.748 15.067 -3.685 1.00 11.09 C ANISOU 314 CG1 ILE A 231 1447 1355 1410 48 116 -114 C ATOM 315 CG2 ILE A 231 0.621 16.901 -2.259 1.00 9.63 C ANISOU 315 CG2 ILE A 231 1282 1122 1252 -20 24 -67 C ATOM 316 CD1 ILE A 231 2.868 16.043 -3.736 1.00 14.77 C ANISOU 316 CD1 ILE A 231 1722 1922 1968 -18 13 -64 C ATOM 317 N ALA A 232 -1.295 15.332 -0.264 1.00 6.06 N ANISOU 317 N ALA A 232 782 798 720 7 -39 -68 N ATOM 318 CA ALA A 232 -2.413 15.889 0.471 1.00 6.31 C ANISOU 318 CA ALA A 232 793 817 785 1 23 -45 C ATOM 319 C ALA A 232 -2.747 17.281 -0.070 1.00 6.99 C ANISOU 319 C ALA A 232 921 885 849 -1 9 -20 C ATOM 320 O ALA A 232 -1.845 18.084 -0.332 1.00 7.70 O ANISOU 320 O ALA A 232 1014 926 986 4 68 -65 O ATOM 321 CB ALA A 232 -2.049 15.991 1.941 1.00 6.61 C ANISOU 321 CB ALA A 232 868 860 783 66 11 -39 C ATOM 322 N THR A 233 -4.033 17.579 -0.216 1.00 7.36 N ANISOU 322 N THR A 233 913 965 918 -11 19 -14 N ATOM 323 CA THR A 233 -4.444 18.914 -0.689 1.00 8.31 C ANISOU 323 CA THR A 233 1044 1065 1045 18 0 -9 C ATOM 324 C THR A 233 -5.187 19.684 0.389 1.00 8.79 C ANISOU 324 C THR A 233 1116 1097 1124 35 11 -7 C ATOM 325 O THR A 233 -5.634 20.813 0.168 1.00 10.04 O ANISOU 325 O THR A 233 1300 1279 1235 158 33 29 O ATOM 326 CB THR A 233 -5.302 18.837 -1.951 1.00 8.75 C ANISOU 326 CB THR A 233 1133 1116 1075 12 0 4 C ATOM 327 OG1 THR A 233 -6.494 18.094 -1.688 1.00 10.34 O ANISOU 327 OG1 THR A 233 1209 1409 1308 -52 -59 -1 O ATOM 328 CG2 THR A 233 -4.599 18.070 -3.041 1.00 9.67 C ANISOU 328 CG2 THR A 233 1248 1234 1193 57 36 -15 C ATOM 329 N LYS A 234 -5.290 19.067 1.552 1.00 8.62 N ANISOU 329 N LYS A 234 1083 1120 1070 37 -7 -30 N ATOM 330 CA LYS A 234 -5.933 19.645 2.715 1.00 9.23 C ANISOU 330 CA LYS A 234 1170 1175 1159 49 3 -19 C ATOM 331 C LYS A 234 -5.180 19.124 3.931 1.00 9.24 C ANISOU 331 C LYS A 234 1190 1173 1146 71 13 -4 C ATOM 332 O LYS A 234 -4.382 18.192 3.822 1.00 9.46 O ANISOU 332 O LYS A 234 1173 1307 1113 142 9 -46 O ATOM 333 CB LYS A 234 -7.405 19.222 2.773 1.00 9.45 C ANISOU 333 CB LYS A 234 1165 1242 1183 84 -12 -21 C ATOM 334 CG LYS A 234 -7.639 17.757 3.110 1.00 11.49 C ANISOU 334 CG LYS A 234 1486 1438 1441 -11 -17 -11 C ATOM 335 CD LYS A 234 -9.126 17.460 3.297 1.00 14.35 C ANISOU 335 CD LYS A 234 1684 1872 1893 -8 2 -18 C ATOM 336 CE LYS A 234 -9.348 16.309 4.264 1.00 16.86 C ANISOU 336 CE LYS A 234 2117 2116 2172 18 78 58 C ATOM 337 NZ LYS A 234 -8.518 16.488 5.486 1.00 18.84 N ANISOU 337 NZ LYS A 234 2362 2452 2342 0 -21 3 N ATOM 338 N GLN A 235 -5.412 19.746 5.079 1.00 9.26 N ANISOU 338 N GLN A 235 1180 1193 1145 67 -13 0 N ATOM 339 CA GLN A 235 -4.869 19.279 6.342 1.00 9.58 C ANISOU 339 CA GLN A 235 1174 1244 1220 24 -1 27 C ATOM 340 C GLN A 235 -5.574 17.997 6.784 1.00 9.31 C ANISOU 340 C GLN A 235 1104 1238 1195 16 -10 56 C ATOM 341 O GLN A 235 -6.798 17.846 6.627 1.00 9.12 O ANISOU 341 O GLN A 235 991 1290 1181 23 19 80 O ATOM 342 CB GLN A 235 -5.070 20.328 7.430 1.00 10.44 C ANISOU 342 CB GLN A 235 1327 1314 1325 37 -58 -9 C ATOM 343 CG GLN A 235 -4.339 21.645 7.228 1.00 12.77 C ANISOU 343 CG GLN A 235 1545 1629 1675 -29 24 111 C ATOM 344 CD GLN A 235 -4.393 22.530 8.468 1.00 16.20 C ANISOU 344 CD GLN A 235 2088 2057 2009 -28 -17 -57 C ATOM 345 OE1 GLN A 235 -4.022 22.093 9.555 1.00 19.35 O ANISOU 345 OE1 GLN A 235 2483 2535 2334 -34 -58 119 O ATOM 346 NE2 GLN A 235 -4.848 23.769 8.311 1.00 17.40 N ANISOU 346 NE2 GLN A 235 2197 2190 2223 7 -54 62 N ATOM 347 N PHE A 236 -4.792 17.053 7.290 1.00 8.25 N ANISOU 347 N PHE A 236 948 1075 1110 22 25 32 N ATOM 348 CA PHE A 236 -5.330 15.886 7.959 1.00 7.91 C ANISOU 348 CA PHE A 236 941 1031 1030 16 9 -2 C ATOM 349 C PHE A 236 -4.832 15.991 9.379 1.00 8.15 C ANISOU 349 C PHE A 236 979 1084 1033 -30 0 10 C ATOM 350 O PHE A 236 -3.678 16.388 9.602 1.00 9.07 O ANISOU 350 O PHE A 236 912 1423 1108 -69 -37 57 O ATOM 351 CB PHE A 236 -4.849 14.579 7.333 1.00 7.62 C ANISOU 351 CB PHE A 236 984 957 951 24 56 21 C ATOM 352 CG PHE A 236 -5.448 14.308 5.982 1.00 7.70 C ANISOU 352 CG PHE A 236 977 943 1005 34 38 -22 C ATOM 353 CD1 PHE A 236 -6.566 13.507 5.854 1.00 8.43 C ANISOU 353 CD1 PHE A 236 1105 1040 1057 -34 47 -38 C ATOM 354 CD2 PHE A 236 -4.901 14.859 4.846 1.00 9.08 C ANISOU 354 CD2 PHE A 236 1121 1212 1117 0 60 64 C ATOM 355 CE1 PHE A 236 -7.121 13.255 4.628 1.00 9.11 C ANISOU 355 CE1 PHE A 236 1092 1211 1156 37 17 48 C ATOM 356 CE2 PHE A 236 -5.457 14.612 3.604 1.00 9.20 C ANISOU 356 CE2 PHE A 236 1126 1177 1192 -74 23 24 C ATOM 357 CZ PHE A 236 -6.559 13.810 3.493 1.00 7.86 C ANISOU 357 CZ PHE A 236 940 1144 900 8 -67 15 C ATOM 358 N SER A 237 -5.701 15.682 10.331 1.00 7.20 N ANISOU 358 N SER A 237 831 946 957 -22 0 -40 N ATOM 359 CA SER A 237 -5.338 15.632 11.729 1.00 7.68 C ANISOU 359 CA SER A 237 934 989 995 -4 2 25 C ATOM 360 C SER A 237 -4.955 14.216 12.149 1.00 7.44 C ANISOU 360 C SER A 237 916 953 957 -17 -4 -37 C ATOM 361 O SER A 237 -5.440 13.241 11.583 1.00 6.56 O ANISOU 361 O SER A 237 808 822 862 -12 -41 -3 O ATOM 362 CB SER A 237 -6.522 16.097 12.577 1.00 8.01 C ANISOU 362 CB SER A 237 996 1034 1011 32 6 -20 C ATOM 363 OG SER A 237 -6.804 17.458 12.340 1.00 10.89 O ANISOU 363 OG SER A 237 1414 1226 1495 11 -19 150 O ATOM 364 N ARG A 238 -4.102 14.108 13.169 1.00 8.21 N ANISOU 364 N ARG A 238 1012 1043 1063 -23 -26 -14 N ATOM 365 CA ARG A 238 -3.718 12.812 13.698 1.00 8.70 C ANISOU 365 CA ARG A 238 1093 1125 1086 -14 -35 -2 C ATOM 366 C ARG A 238 -4.968 12.005 13.975 1.00 8.37 C ANISOU 366 C ARG A 238 1050 1081 1046 11 -15 3 C ATOM 367 O ARG A 238 -5.893 12.502 14.616 1.00 8.67 O ANISOU 367 O ARG A 238 1037 1131 1126 18 -63 1 O ATOM 368 CB ARG A 238 -2.904 12.958 14.978 1.00 9.63 C ANISOU 368 CB ARG A 238 1188 1334 1137 -49 -8 -36 C ATOM 369 CG ARG A 238 -1.987 11.801 15.197 1.00 13.38 C ANISOU 369 CG ARG A 238 1685 1741 1657 101 -81 -46 C ATOM 370 CD ARG A 238 -2.559 10.660 15.984 1.00 19.90 C ANISOU 370 CD ARG A 238 2526 2474 2561 -113 61 91 C ATOM 371 NE ARG A 238 -1.522 9.805 16.584 1.00 24.49 N ANISOU 371 NE ARG A 238 3040 3076 3187 122 -18 112 N ATOM 372 CZ ARG A 238 -0.523 10.247 17.338 1.00 27.39 C ANISOU 372 CZ ARG A 238 3458 3486 3461 -14 -15 -7 C ATOM 373 NH1 ARG A 238 -0.392 11.542 17.601 1.00 29.79 N ANISOU 373 NH1 ARG A 238 3778 3751 3789 -4 12 -3 N ATOM 374 NH2 ARG A 238 0.358 9.389 17.836 1.00 28.77 N ANISOU 374 NH2 ARG A 238 3642 3639 3650 16 -9 11 N ATOM 375 N GLY A 239 -4.987 10.770 13.478 1.00 7.65 N ANISOU 375 N GLY A 239 956 994 956 19 0 -10 N ATOM 376 CA GLY A 239 -6.099 9.855 13.688 1.00 8.24 C ANISOU 376 CA GLY A 239 1017 1035 1079 15 17 1 C ATOM 377 C GLY A 239 -7.181 9.900 12.620 1.00 8.29 C ANISOU 377 C GLY A 239 1001 1037 1110 13 2 3 C ATOM 378 O GLY A 239 -8.064 9.038 12.578 1.00 9.88 O ANISOU 378 O GLY A 239 1215 1208 1327 -7 -13 68 O ATOM 379 N ASP A 240 -7.118 10.884 11.735 1.00 7.87 N ANISOU 379 N ASP A 240 958 1037 992 37 1 -22 N ATOM 380 CA ASP A 240 -8.119 10.997 10.682 1.00 7.76 C ANISOU 380 CA ASP A 240 951 1004 992 9 0 -11 C ATOM 381 C ASP A 240 -7.980 9.896 9.640 1.00 6.80 C ANISOU 381 C ASP A 240 796 912 873 -19 18 -10 C ATOM 382 O ASP A 240 -6.877 9.488 9.273 1.00 6.48 O ANISOU 382 O ASP A 240 752 847 862 27 -21 -91 O ATOM 383 CB ASP A 240 -7.952 12.310 9.914 1.00 8.71 C ANISOU 383 CB ASP A 240 1120 1097 1092 -30 16 27 C ATOM 384 CG ASP A 240 -8.550 13.517 10.617 1.00 10.54 C ANISOU 384 CG ASP A 240 1268 1314 1422 0 10 -55 C ATOM 385 OD1 ASP A 240 -9.112 13.388 11.728 1.00 12.74 O ANISOU 385 OD1 ASP A 240 1621 1634 1585 40 112 -10 O ATOM 386 OD2 ASP A 240 -8.487 14.663 10.093 1.00 13.10 O ANISOU 386 OD2 ASP A 240 1578 1697 1700 81 -22 84 O ATOM 387 N PHE A 241 -9.114 9.452 9.121 1.00 6.83 N ANISOU 387 N PHE A 241 832 945 815 -20 -16 9 N ATOM 388 CA PHE A 241 -9.150 8.549 7.987 1.00 6.87 C ANISOU 388 CA PHE A 241 826 879 906 0 34 12 C ATOM 389 C PHE A 241 -8.552 9.279 6.802 1.00 7.02 C ANISOU 389 C PHE A 241 860 842 962 -12 4 6 C ATOM 390 O PHE A 241 -8.886 10.445 6.526 1.00 8.43 O ANISOU 390 O PHE A 241 1084 907 1212 -86 81 14 O ATOM 391 CB PHE A 241 -10.619 8.199 7.692 1.00 7.18 C ANISOU 391 CB PHE A 241 831 967 929 -7 13 16 C ATOM 392 CG PHE A 241 -10.827 7.354 6.470 1.00 8.17 C ANISOU 392 CG PHE A 241 927 1048 1129 -35 -59 -4 C ATOM 393 CD1 PHE A 241 -10.884 5.979 6.573 1.00 10.07 C ANISOU 393 CD1 PHE A 241 1411 1121 1294 58 -38 37 C ATOM 394 CD2 PHE A 241 -10.998 7.936 5.234 1.00 7.48 C ANISOU 394 CD2 PHE A 241 887 997 956 -16 127 -81 C ATOM 395 CE1 PHE A 241 -11.077 5.197 5.458 1.00 10.36 C ANISOU 395 CE1 PHE A 241 1437 1183 1318 -20 -74 -1 C ATOM 396 CE2 PHE A 241 -11.189 7.160 4.110 1.00 7.75 C ANISOU 396 CE2 PHE A 241 908 1093 943 -91 -39 -12 C ATOM 397 CZ PHE A 241 -11.233 5.792 4.229 1.00 8.31 C ANISOU 397 CZ PHE A 241 1093 1056 1007 2 8 -134 C ATOM 398 N VAL A 242 -7.695 8.585 6.077 1.00 6.96 N ANISOU 398 N VAL A 242 885 834 923 -30 68 19 N ATOM 399 CA VAL A 242 -7.137 9.147 4.869 1.00 6.66 C ANISOU 399 CA VAL A 242 821 859 848 -9 45 -7 C ATOM 400 C VAL A 242 -7.757 8.466 3.647 1.00 6.55 C ANISOU 400 C VAL A 242 789 838 861 -8 69 14 C ATOM 401 O VAL A 242 -8.422 9.109 2.832 1.00 7.90 O ANISOU 401 O VAL A 242 992 948 1061 -39 -15 36 O ATOM 402 CB VAL A 242 -5.607 9.055 4.869 1.00 6.85 C ANISOU 402 CB VAL A 242 814 916 870 -10 -14 6 C ATOM 403 CG1 VAL A 242 -5.046 9.508 3.545 1.00 8.43 C ANISOU 403 CG1 VAL A 242 1069 1081 1051 -69 15 13 C ATOM 404 CG2 VAL A 242 -5.033 9.894 6.011 1.00 6.97 C ANISOU 404 CG2 VAL A 242 765 979 905 -67 55 24 C ATOM 405 N VAL A 243 -7.570 7.153 3.535 1.00 5.84 N ANISOU 405 N VAL A 243 735 695 789 -10 101 4 N ATOM 406 CA VAL A 243 -8.066 6.442 2.367 1.00 6.06 C ANISOU 406 CA VAL A 243 769 713 819 -12 49 39 C ATOM 407 C VAL A 243 -8.006 4.936 2.595 1.00 6.02 C ANISOU 407 C VAL A 243 783 702 800 24 25 -1 C ATOM 408 O VAL A 243 -7.283 4.476 3.450 1.00 6.89 O ANISOU 408 O VAL A 243 874 758 986 -65 -121 -49 O ATOM 409 CB VAL A 243 -7.191 6.799 1.129 1.00 6.93 C ANISOU 409 CB VAL A 243 917 818 898 18 92 20 C ATOM 410 CG1 VAL A 243 -5.825 6.126 1.232 1.00 8.45 C ANISOU 410 CG1 VAL A 243 1012 1037 1161 -8 25 27 C ATOM 411 CG2 VAL A 243 -7.881 6.458 -0.127 1.00 7.56 C ANISOU 411 CG2 VAL A 243 1052 793 1025 -10 42 41 C ATOM 412 N GLU A 244 -8.843 4.183 1.887 1.00 5.81 N ANISOU 412 N GLU A 244 771 721 715 23 16 -3 N ATOM 413 CA GLU A 244 -8.769 2.717 1.932 1.00 6.05 C ANISOU 413 CA GLU A 244 801 736 758 5 22 28 C ATOM 414 C GLU A 244 -7.711 2.192 0.941 1.00 6.55 C ANISOU 414 C GLU A 244 925 807 757 37 70 39 C ATOM 415 O GLU A 244 -7.496 2.783 -0.121 1.00 6.96 O ANISOU 415 O GLU A 244 1016 816 810 58 79 112 O ATOM 416 CB GLU A 244 -10.127 2.073 1.589 1.00 6.22 C ANISOU 416 CB GLU A 244 818 778 764 1 24 18 C ATOM 417 CG GLU A 244 -10.129 0.547 1.684 1.00 7.70 C ANISOU 417 CG GLU A 244 1034 937 955 54 78 -3 C ATOM 418 CD GLU A 244 -11.433 -0.128 1.293 1.00 9.68 C ANISOU 418 CD GLU A 244 1250 1260 1168 28 8 3 C ATOM 419 OE1 GLU A 244 -12.404 0.542 0.851 1.00 11.76 O ANISOU 419 OE1 GLU A 244 1224 1636 1606 94 -121 -26 O ATOM 420 OE2 GLU A 244 -11.476 -1.371 1.403 1.00 11.62 O ANISOU 420 OE2 GLU A 244 1424 1371 1618 26 -32 55 O ATOM 421 N TYR A 245 -7.016 1.105 1.301 1.00 6.33 N ANISOU 421 N TYR A 245 914 769 721 52 104 28 N ATOM 422 CA TYR A 245 -6.182 0.368 0.335 1.00 6.75 C ANISOU 422 CA TYR A 245 885 836 843 21 97 19 C ATOM 423 C TYR A 245 -7.173 -0.602 -0.327 1.00 6.99 C ANISOU 423 C TYR A 245 919 865 872 29 95 0 C ATOM 424 O TYR A 245 -7.454 -1.707 0.177 1.00 7.13 O ANISOU 424 O TYR A 245 918 889 900 62 181 9 O ATOM 425 CB TYR A 245 -5.021 -0.364 1.006 1.00 6.70 C ANISOU 425 CB TYR A 245 886 755 905 -43 43 -30 C ATOM 426 CG TYR A 245 -4.044 -0.910 -0.009 1.00 6.23 C ANISOU 426 CG TYR A 245 781 721 862 -4 29 -29 C ATOM 427 CD1 TYR A 245 -2.979 -0.142 -0.438 1.00 6.09 C ANISOU 427 CD1 TYR A 245 705 695 911 -29 60 16 C ATOM 428 CD2 TYR A 245 -4.173 -2.184 -0.537 1.00 4.22 C ANISOU 428 CD2 TYR A 245 468 446 686 -169 -50 128 C ATOM 429 CE1 TYR A 245 -2.105 -0.602 -1.367 1.00 5.83 C ANISOU 429 CE1 TYR A 245 701 765 749 4 101 151 C ATOM 430 CE2 TYR A 245 -3.296 -2.668 -1.490 1.00 5.41 C ANISOU 430 CE2 TYR A 245 717 457 881 -132 -30 13 C ATOM 431 CZ TYR A 245 -2.231 -1.872 -1.894 1.00 6.05 C ANISOU 431 CZ TYR A 245 591 954 751 -25 34 36 C ATOM 432 OH TYR A 245 -1.335 -2.333 -2.828 1.00 6.91 O ANISOU 432 OH TYR A 245 782 881 961 0 158 20 O ATOM 433 N HIS A 246 -7.764 -0.147 -1.430 1.00 7.38 N ANISOU 433 N HIS A 246 922 941 938 18 65 21 N ATOM 434 CA HIS A 246 -8.839 -0.849 -2.093 1.00 8.11 C ANISOU 434 CA HIS A 246 1065 1022 991 -12 13 3 C ATOM 435 C HIS A 246 -8.326 -1.746 -3.201 1.00 8.63 C ANISOU 435 C HIS A 246 1077 1142 1060 -23 43 -20 C ATOM 436 O HIS A 246 -7.482 -1.320 -3.972 1.00 10.69 O ANISOU 436 O HIS A 246 1292 1438 1330 -126 125 -89 O ATOM 437 CB HIS A 246 -9.765 0.195 -2.705 1.00 8.89 C ANISOU 437 CB HIS A 246 1152 1087 1137 15 49 -22 C ATOM 438 CG HIS A 246 -11.061 -0.353 -3.182 1.00 11.22 C ANISOU 438 CG HIS A 246 1416 1386 1459 18 -10 37 C ATOM 439 ND1 HIS A 246 -12.194 -0.371 -2.400 1.00 14.41 N ANISOU 439 ND1 HIS A 246 1687 1914 1873 15 60 21 N ATOM 440 CD2 HIS A 246 -11.404 -0.908 -4.360 1.00 13.04 C ANISOU 440 CD2 HIS A 246 1806 1582 1564 85 -94 -12 C ATOM 441 CE1 HIS A 246 -13.187 -0.914 -3.085 1.00 14.75 C ANISOU 441 CE1 HIS A 246 1939 1856 1807 18 -76 -75 C ATOM 442 NE2 HIS A 246 -12.732 -1.241 -4.280 1.00 15.51 N ANISOU 442 NE2 HIS A 246 1989 1968 1935 -26 97 32 N ATOM 443 N GLY A 247 -8.859 -2.959 -3.289 1.00 9.08 N ANISOU 443 N GLY A 247 1178 1189 1082 30 30 -16 N ATOM 444 CA GLY A 247 -8.496 -3.908 -4.326 1.00 9.38 C ANISOU 444 CA GLY A 247 1182 1207 1174 21 -32 -45 C ATOM 445 C GLY A 247 -9.319 -5.181 -4.161 1.00 10.09 C ANISOU 445 C GLY A 247 1267 1293 1271 10 17 -19 C ATOM 446 O GLY A 247 -10.378 -5.206 -3.519 1.00 11.88 O ANISOU 446 O GLY A 247 1453 1473 1585 50 73 -69 O ATOM 447 N ASP A 248 -8.848 -6.260 -4.761 1.00 10.12 N ANISOU 447 N ASP A 248 1288 1296 1261 51 -29 -8 N ATOM 448 CA ASP A 248 -9.536 -7.529 -4.681 1.00 10.87 C ANISOU 448 CA ASP A 248 1334 1405 1388 41 -49 24 C ATOM 449 C ASP A 248 -9.077 -8.287 -3.444 1.00 9.82 C ANISOU 449 C ASP A 248 1188 1243 1299 13 -23 21 C ATOM 450 O ASP A 248 -7.896 -8.567 -3.295 1.00 9.09 O ANISOU 450 O ASP A 248 961 1097 1393 -95 -115 31 O ATOM 451 CB ASP A 248 -9.204 -8.366 -5.913 1.00 12.02 C ANISOU 451 CB ASP A 248 1512 1554 1498 58 -8 -53 C ATOM 452 CG ASP A 248 -9.186 -7.548 -7.195 1.00 16.97 C ANISOU 452 CG ASP A 248 2233 2140 2072 87 9 157 C ATOM 453 OD1 ASP A 248 -10.178 -6.842 -7.466 1.00 21.00 O ANISOU 453 OD1 ASP A 248 2488 2763 2726 291 -80 60 O ATOM 454 OD2 ASP A 248 -8.225 -7.552 -8.001 1.00 21.71 O ANISOU 454 OD2 ASP A 248 2620 2936 2693 66 226 104 O ATOM 455 N LEU A 249 -10.011 -8.611 -2.570 1.00 8.48 N ANISOU 455 N LEU A 249 1020 1095 1104 5 -60 14 N ATOM 456 CA LEU A 249 -9.721 -9.407 -1.389 1.00 7.95 C ANISOU 456 CA LEU A 249 976 1030 1012 1 -31 -5 C ATOM 457 C LEU A 249 -9.658 -10.886 -1.742 1.00 7.38 C ANISOU 457 C LEU A 249 886 963 954 -17 -52 24 C ATOM 458 O LEU A 249 -10.668 -11.484 -2.185 1.00 7.80 O ANISOU 458 O LEU A 249 938 975 1048 -19 -155 -72 O ATOM 459 CB LEU A 249 -10.791 -9.172 -0.334 1.00 8.06 C ANISOU 459 CB LEU A 249 964 1055 1041 3 -11 22 C ATOM 460 CG LEU A 249 -10.573 -9.839 1.014 1.00 8.70 C ANISOU 460 CG LEU A 249 1049 1129 1125 21 11 47 C ATOM 461 CD1 LEU A 249 -9.315 -9.356 1.665 1.00 7.14 C ANISOU 461 CD1 LEU A 249 900 935 877 55 12 52 C ATOM 462 CD2 LEU A 249 -11.787 -9.573 1.904 1.00 9.89 C ANISOU 462 CD2 LEU A 249 1252 1351 1154 17 65 32 C ATOM 463 N ILE A 250 -8.492 -11.483 -1.509 1.00 6.98 N ANISOU 463 N ILE A 250 819 957 874 -16 -30 -3 N ATOM 464 CA ILE A 250 -8.263 -12.896 -1.779 1.00 6.82 C ANISOU 464 CA ILE A 250 830 904 855 -11 -16 32 C ATOM 465 C ILE A 250 -7.553 -13.604 -0.618 1.00 6.58 C ANISOU 465 C ILE A 250 793 891 814 -5 -32 7 C ATOM 466 O ILE A 250 -7.044 -12.951 0.294 1.00 6.22 O ANISOU 466 O ILE A 250 775 730 857 -43 -58 48 O ATOM 467 CB ILE A 250 -7.468 -13.069 -3.085 1.00 6.99 C ANISOU 467 CB ILE A 250 871 929 856 31 -34 -9 C ATOM 468 CG1 ILE A 250 -6.100 -12.386 -2.986 1.00 7.65 C ANISOU 468 CG1 ILE A 250 926 991 988 -13 -2 12 C ATOM 469 CG2 ILE A 250 -8.292 -12.522 -4.271 1.00 7.30 C ANISOU 469 CG2 ILE A 250 910 939 922 61 -48 38 C ATOM 470 CD1 ILE A 250 -5.262 -12.453 -4.259 1.00 9.04 C ANISOU 470 CD1 ILE A 250 1156 1176 1100 16 11 45 C ATOM 471 N GLU A 251 -7.544 -14.938 -0.664 1.00 7.31 N ANISOU 471 N GLU A 251 880 967 929 -13 -42 32 N ATOM 472 CA GLU A 251 -6.882 -15.780 0.345 1.00 8.28 C ANISOU 472 CA GLU A 251 1027 1096 1020 17 -15 36 C ATOM 473 C GLU A 251 -5.425 -15.998 -0.016 1.00 8.23 C ANISOU 473 C GLU A 251 1013 1124 988 18 -26 25 C ATOM 474 O GLU A 251 -5.037 -15.856 -1.166 1.00 7.74 O ANISOU 474 O GLU A 251 876 1153 912 66 -37 55 O ATOM 475 CB GLU A 251 -7.571 -17.142 0.454 1.00 9.04 C ANISOU 475 CB GLU A 251 1148 1163 1123 -23 -1 45 C ATOM 476 CG GLU A 251 -9.060 -17.075 0.727 1.00 12.58 C ANISOU 476 CG GLU A 251 1437 1759 1584 78 1 19 C ATOM 477 CD GLU A 251 -9.609 -18.383 1.256 1.00 16.03 C ANISOU 477 CD GLU A 251 2033 1966 2089 -12 51 43 C ATOM 478 OE1 GLU A 251 -9.240 -18.767 2.386 1.00 19.50 O ANISOU 478 OE1 GLU A 251 2514 2595 2299 76 -45 30 O ATOM 479 OE2 GLU A 251 -10.421 -19.032 0.558 1.00 18.73 O ANISOU 479 OE2 GLU A 251 2350 2499 2266 0 -47 -65 O ATOM 480 N ILE A 252 -4.622 -16.384 0.968 1.00 8.09 N ANISOU 480 N ILE A 252 1028 1114 931 25 -27 42 N ATOM 481 CA ILE A 252 -3.178 -16.483 0.777 1.00 8.53 C ANISOU 481 CA ILE A 252 1077 1150 1011 45 -21 15 C ATOM 482 C ILE A 252 -2.749 -17.449 -0.333 1.00 8.84 C ANISOU 482 C ILE A 252 1119 1163 1074 62 -19 23 C ATOM 483 O ILE A 252 -1.829 -17.146 -1.078 1.00 8.95 O ANISOU 483 O ILE A 252 1151 1277 971 162 -47 63 O ATOM 484 CB ILE A 252 -2.484 -16.828 2.110 1.00 8.57 C ANISOU 484 CB ILE A 252 1047 1172 1036 28 -40 -1 C ATOM 485 CG1 ILE A 252 -0.966 -16.895 1.923 1.00 8.19 C ANISOU 485 CG1 ILE A 252 1053 1109 949 49 22 -9 C ATOM 486 CG2 ILE A 252 -3.015 -18.118 2.662 1.00 9.63 C ANISOU 486 CG2 ILE A 252 1154 1299 1206 37 -16 55 C ATOM 487 CD1 ILE A 252 -0.224 -17.319 3.185 1.00 9.09 C ANISOU 487 CD1 ILE A 252 1087 1277 1089 58 -31 4 C ATOM 488 N THR A 253 -3.403 -18.587 -0.461 1.00 9.88 N ANISOU 488 N THR A 253 1283 1291 1179 39 -23 24 N ATOM 489 CA THR A 253 -2.977 -19.545 -1.487 1.00 10.88 C ANISOU 489 CA THR A 253 1393 1400 1340 22 3 0 C ATOM 490 C THR A 253 -3.207 -18.954 -2.887 1.00 10.66 C ANISOU 490 C THR A 253 1360 1374 1315 7 12 -6 C ATOM 491 O THR A 253 -2.340 -19.039 -3.747 1.00 10.56 O ANISOU 491 O THR A 253 1402 1316 1291 27 35 -53 O ATOM 492 CB THR A 253 -3.647 -20.909 -1.294 1.00 11.69 C ANISOU 492 CB THR A 253 1488 1518 1435 0 7 26 C ATOM 493 OG1 THR A 253 -5.078 -20.781 -1.332 1.00 13.81 O ANISOU 493 OG1 THR A 253 1607 1914 1723 17 -28 31 O ATOM 494 CG2 THR A 253 -3.346 -21.439 0.111 1.00 12.22 C ANISOU 494 CG2 THR A 253 1536 1599 1505 26 -19 23 C ATOM 495 N ASP A 254 -4.355 -18.312 -3.085 1.00 10.58 N ANISOU 495 N ASP A 254 1347 1334 1336 -13 -3 -13 N ATOM 496 CA ASP A 254 -4.658 -17.633 -4.337 1.00 10.97 C ANISOU 496 CA ASP A 254 1414 1391 1361 -9 -2 -22 C ATOM 497 C ASP A 254 -3.704 -16.457 -4.560 1.00 10.10 C ANISOU 497 C ASP A 254 1300 1305 1229 2 -13 -27 C ATOM 498 O ASP A 254 -3.252 -16.202 -5.680 1.00 9.75 O ANISOU 498 O ASP A 254 1289 1224 1191 -35 -48 4 O ATOM 499 CB ASP A 254 -6.090 -17.112 -4.309 1.00 12.18 C ANISOU 499 CB ASP A 254 1534 1539 1553 -1 3 -42 C ATOM 500 CG ASP A 254 -6.488 -16.441 -5.603 1.00 16.12 C ANISOU 500 CG ASP A 254 2136 2053 1933 20 -67 70 C ATOM 501 OD1 ASP A 254 -6.032 -16.902 -6.674 1.00 20.74 O ANISOU 501 OD1 ASP A 254 2683 2834 2360 92 106 -13 O ATOM 502 OD2 ASP A 254 -7.264 -15.458 -5.657 1.00 20.42 O ANISOU 502 OD2 ASP A 254 2649 2475 2634 212 -10 -5 O ATOM 503 N ALA A 255 -3.380 -15.740 -3.489 1.00 9.29 N ANISOU 503 N ALA A 255 1208 1184 1135 20 6 -17 N ATOM 504 CA ALA A 255 -2.470 -14.613 -3.612 1.00 8.76 C ANISOU 504 CA ALA A 255 1136 1129 1063 6 -37 0 C ATOM 505 C ALA A 255 -1.085 -15.053 -4.094 1.00 8.47 C ANISOU 505 C ALA A 255 1130 1100 986 -20 -18 -41 C ATOM 506 O ALA A 255 -0.469 -14.388 -4.919 1.00 8.61 O ANISOU 506 O ALA A 255 1184 1119 966 -35 -79 4 O ATOM 507 CB ALA A 255 -2.359 -13.849 -2.290 1.00 8.47 C ANISOU 507 CB ALA A 255 1091 1061 1066 22 -22 0 C ATOM 508 N LYS A 256 -0.585 -16.158 -3.559 1.00 8.72 N ANISOU 508 N LYS A 256 1143 1127 1041 9 -15 -21 N ATOM 509 CA LYS A 256 0.724 -16.666 -3.954 1.00 9.58 C ANISOU 509 CA LYS A 256 1226 1255 1157 12 7 -19 C ATOM 510 C LYS A 256 0.749 -16.954 -5.447 1.00 9.80 C ANISOU 510 C LYS A 256 1247 1278 1196 42 12 13 C ATOM 511 O LYS A 256 1.714 -16.620 -6.138 1.00 10.56 O ANISOU 511 O LYS A 256 1346 1448 1218 53 5 61 O ATOM 512 CB LYS A 256 1.037 -17.941 -3.185 1.00 10.18 C ANISOU 512 CB LYS A 256 1297 1331 1238 48 32 0 C ATOM 513 CG LYS A 256 1.092 -17.744 -1.688 1.00 12.24 C ANISOU 513 CG LYS A 256 1596 1615 1440 16 4 -30 C ATOM 514 CD LYS A 256 2.460 -17.954 -1.155 1.00 14.66 C ANISOU 514 CD LYS A 256 1801 1944 1825 14 -33 -15 C ATOM 515 CE LYS A 256 2.439 -17.943 0.359 1.00 15.87 C ANISOU 515 CE LYS A 256 2044 2075 1909 1 29 1 C ATOM 516 NZ LYS A 256 3.790 -17.607 0.873 1.00 18.72 N ANISOU 516 NZ LYS A 256 2281 2458 2373 -1 -49 0 N ATOM 517 N LYS A 257 -0.323 -17.554 -5.942 1.00 10.21 N ANISOU 517 N LYS A 257 1329 1301 1248 30 14 -5 N ATOM 518 CA LYS A 257 -0.411 -17.905 -7.353 1.00 10.66 C ANISOU 518 CA LYS A 257 1383 1350 1315 28 0 -7 C ATOM 519 C LYS A 257 -0.364 -16.650 -8.209 1.00 10.59 C ANISOU 519 C LYS A 257 1366 1343 1315 37 28 13 C ATOM 520 O LYS A 257 0.409 -16.559 -9.164 1.00 10.61 O ANISOU 520 O LYS A 257 1391 1360 1279 64 20 26 O ATOM 521 CB LYS A 257 -1.691 -18.690 -7.611 1.00 11.11 C ANISOU 521 CB LYS A 257 1413 1415 1393 1 18 -9 C ATOM 522 CG LYS A 257 -1.650 -20.096 -7.013 1.00 13.28 C ANISOU 522 CG LYS A 257 1750 1638 1657 41 -30 27 C ATOM 523 CD LYS A 257 -2.954 -20.855 -7.207 1.00 15.17 C ANISOU 523 CD LYS A 257 1889 1924 1951 -48 -4 5 C ATOM 524 CE LYS A 257 -2.940 -22.199 -6.477 1.00 16.02 C ANISOU 524 CE LYS A 257 2082 1994 2010 -1 -9 19 C ATOM 525 NZ LYS A 257 -4.308 -22.792 -6.368 1.00 17.51 N ANISOU 525 NZ LYS A 257 2133 2330 2187 -32 23 36 N ATOM 526 N ARG A 258 -1.174 -15.665 -7.843 1.00 10.31 N ANISOU 526 N ARG A 258 1363 1300 1250 21 11 -9 N ATOM 527 CA ARG A 258 -1.215 -14.419 -8.592 1.00 10.60 C ANISOU 527 CA ARG A 258 1398 1296 1332 4 -2 -9 C ATOM 528 C ARG A 258 0.147 -13.732 -8.593 1.00 11.34 C ANISOU 528 C ARG A 258 1446 1418 1445 12 26 25 C ATOM 529 O ARG A 258 0.627 -13.295 -9.639 1.00 11.34 O ANISOU 529 O ARG A 258 1446 1397 1463 -13 31 45 O ATOM 530 CB ARG A 258 -2.251 -13.472 -7.993 1.00 10.52 C ANISOU 530 CB ARG A 258 1354 1345 1298 19 18 35 C ATOM 531 CG ARG A 258 -3.691 -13.887 -8.165 1.00 10.34 C ANISOU 531 CG ARG A 258 1395 1269 1263 -8 5 27 C ATOM 532 CD ARG A 258 -4.653 -12.766 -7.845 1.00 10.62 C ANISOU 532 CD ARG A 258 1389 1394 1251 39 -18 21 C ATOM 533 NE ARG A 258 -6.038 -13.198 -7.905 1.00 11.95 N ANISOU 533 NE ARG A 258 1531 1547 1462 -31 4 35 N ATOM 534 CZ ARG A 258 -7.078 -12.378 -7.886 1.00 12.80 C ANISOU 534 CZ ARG A 258 1656 1639 1568 14 -25 -1 C ATOM 535 NH1 ARG A 258 -6.893 -11.066 -7.807 1.00 13.66 N ANISOU 535 NH1 ARG A 258 1826 1716 1646 61 2 33 N ATOM 536 NH2 ARG A 258 -8.304 -12.874 -7.950 1.00 13.88 N ANISOU 536 NH2 ARG A 258 1664 1864 1746 19 61 76 N ATOM 537 N GLU A 259 0.759 -13.641 -7.415 1.00 12.00 N ANISOU 537 N GLU A 259 1542 1479 1537 -14 -1 14 N ATOM 538 CA GLU A 259 2.059 -12.988 -7.261 1.00 13.24 C ANISOU 538 CA GLU A 259 1659 1672 1697 -4 1 7 C ATOM 539 C GLU A 259 3.071 -13.594 -8.246 1.00 13.53 C ANISOU 539 C GLU A 259 1682 1721 1736 10 13 35 C ATOM 540 O GLU A 259 3.879 -12.883 -8.834 1.00 13.77 O ANISOU 540 O GLU A 259 1708 1765 1759 37 39 62 O ATOM 541 CB GLU A 259 2.551 -13.085 -5.799 1.00 13.76 C ANISOU 541 CB GLU A 259 1697 1790 1738 3 2 53 C ATOM 542 CG GLU A 259 3.590 -12.023 -5.448 1.00 15.84 C ANISOU 542 CG GLU A 259 2036 1950 2029 -17 -38 -18 C ATOM 543 CD GLU A 259 3.903 -11.872 -3.962 1.00 17.82 C ANISOU 543 CD GLU A 259 2286 2329 2155 -8 -59 48 C ATOM 544 OE1 GLU A 259 3.124 -12.298 -3.089 1.00 17.98 O ANISOU 544 OE1 GLU A 259 2230 2392 2209 2 20 45 O ATOM 545 OE2 GLU A 259 4.956 -11.275 -3.668 1.00 19.96 O ANISOU 545 OE2 GLU A 259 2402 2586 2595 -47 -24 75 O ATOM 546 N ALA A 260 3.016 -14.907 -8.432 1.00 13.67 N ANISOU 546 N ALA A 260 1717 1743 1731 14 15 10 N ATOM 547 CA ALA A 260 3.940 -15.575 -9.345 1.00 14.01 C ANISOU 547 CA ALA A 260 1785 1779 1758 14 13 16 C ATOM 548 C ALA A 260 3.636 -15.186 -10.788 1.00 13.90 C ANISOU 548 C ALA A 260 1761 1755 1766 15 4 21 C ATOM 549 O ALA A 260 4.550 -14.927 -11.580 1.00 14.67 O ANISOU 549 O ALA A 260 1833 1908 1832 45 40 91 O ATOM 550 CB ALA A 260 3.876 -17.077 -9.166 1.00 14.08 C ANISOU 550 CB ALA A 260 1794 1784 1771 -3 -4 13 C ATOM 551 N LEU A 261 2.354 -15.132 -11.120 1.00 13.48 N ANISOU 551 N LEU A 261 1715 1677 1729 8 10 18 N ATOM 552 CA LEU A 261 1.927 -14.752 -12.458 1.00 13.15 C ANISOU 552 CA LEU A 261 1682 1641 1673 -13 5 9 C ATOM 553 C LEU A 261 2.326 -13.311 -12.798 1.00 12.71 C ANISOU 553 C LEU A 261 1612 1600 1617 0 11 9 C ATOM 554 O LEU A 261 2.841 -13.042 -13.886 1.00 12.88 O ANISOU 554 O LEU A 261 1653 1599 1639 2 15 59 O ATOM 555 CB LEU A 261 0.412 -14.940 -12.608 1.00 13.44 C ANISOU 555 CB LEU A 261 1703 1713 1687 15 19 19 C ATOM 556 CG LEU A 261 -0.017 -16.400 -12.774 1.00 14.36 C ANISOU 556 CG LEU A 261 1824 1803 1829 3 6 21 C ATOM 557 CD1 LEU A 261 -1.534 -16.538 -12.751 1.00 15.34 C ANISOU 557 CD1 LEU A 261 1861 1981 1984 -26 -5 36 C ATOM 558 CD2 LEU A 261 0.534 -16.998 -14.073 1.00 14.86 C ANISOU 558 CD2 LEU A 261 1914 1875 1854 -12 0 -3 C ATOM 559 N TYR A 262 2.086 -12.391 -11.876 1.00 12.18 N ANISOU 559 N TYR A 262 1561 1515 1549 -10 3 21 N ATOM 560 CA TYR A 262 2.436 -10.990 -12.100 1.00 11.83 C ANISOU 560 CA TYR A 262 1519 1475 1498 -7 7 -7 C ATOM 561 C TYR A 262 3.941 -10.819 -12.290 1.00 12.81 C ANISOU 561 C TYR A 262 1606 1622 1640 -6 37 16 C ATOM 562 O TYR A 262 4.381 -9.927 -13.015 1.00 13.10 O ANISOU 562 O TYR A 262 1673 1629 1673 26 51 44 O ATOM 563 CB TYR A 262 1.996 -10.122 -10.918 1.00 11.31 C ANISOU 563 CB TYR A 262 1445 1436 1416 16 18 18 C ATOM 564 CG TYR A 262 0.506 -10.029 -10.690 1.00 9.61 C ANISOU 564 CG TYR A 262 1294 1174 1183 -54 -6 -4 C ATOM 565 CD1 TYR A 262 0.003 -10.017 -9.402 1.00 8.76 C ANISOU 565 CD1 TYR A 262 1122 1147 1057 13 -5 -32 C ATOM 566 CD2 TYR A 262 -0.393 -9.918 -11.743 1.00 9.66 C ANISOU 566 CD2 TYR A 262 1246 1287 1136 67 56 -21 C ATOM 567 CE1 TYR A 262 -1.343 -9.922 -9.152 1.00 8.78 C ANISOU 567 CE1 TYR A 262 1129 1051 1155 -37 7 33 C ATOM 568 CE2 TYR A 262 -1.768 -9.829 -11.504 1.00 9.43 C ANISOU 568 CE2 TYR A 262 1178 1289 1114 -17 -6 0 C ATOM 569 CZ TYR A 262 -2.231 -9.815 -10.190 1.00 9.15 C ANISOU 569 CZ TYR A 262 1231 1162 1080 -5 -6 47 C ATOM 570 OH TYR A 262 -3.581 -9.716 -9.899 1.00 10.24 O ANISOU 570 OH TYR A 262 1365 1395 1127 86 65 132 O ATOM 571 N ALA A 263 4.725 -11.650 -11.610 1.00 13.61 N ANISOU 571 N ALA A 263 1711 1704 1754 3 22 38 N ATOM 572 CA ALA A 263 6.184 -11.575 -11.679 1.00 14.65 C ANISOU 572 CA ALA A 263 1822 1852 1891 -7 0 26 C ATOM 573 C ALA A 263 6.690 -11.922 -13.075 1.00 15.51 C ANISOU 573 C ALA A 263 1937 1985 1968 -10 12 46 C ATOM 574 O ALA A 263 7.801 -11.538 -13.454 1.00 16.72 O ANISOU 574 O ALA A 263 1989 2179 2182 -27 -8 87 O ATOM 575 CB ALA A 263 6.816 -12.486 -10.631 1.00 14.82 C ANISOU 575 CB ALA A 263 1833 1877 1917 1 0 22 C ATOM 576 N GLN A 264 5.884 -12.645 -13.845 1.00 16.09 N ANISOU 576 N GLN A 264 2017 2049 2046 -16 13 30 N ATOM 577 CA GLN A 264 6.253 -12.990 -15.212 1.00 16.53 C ANISOU 577 CA GLN A 264 2101 2097 2082 1 13 4 C ATOM 578 C GLN A 264 6.137 -11.790 -16.158 1.00 16.42 C ANISOU 578 C GLN A 264 2093 2071 2073 -2 21 1 C ATOM 579 O GLN A 264 6.614 -11.855 -17.286 1.00 16.08 O ANISOU 579 O GLN A 264 2099 2010 2001 17 38 -34 O ATOM 580 CB GLN A 264 5.394 -14.140 -15.743 1.00 17.04 C ANISOU 580 CB GLN A 264 2150 2162 2160 -15 11 -3 C ATOM 581 CG GLN A 264 5.693 -15.486 -15.106 1.00 18.11 C ANISOU 581 CG GLN A 264 2308 2284 2287 40 14 31 C ATOM 582 CD GLN A 264 4.968 -16.628 -15.793 1.00 19.84 C ANISOU 582 CD GLN A 264 2541 2470 2528 -29 -22 6 C ATOM 583 OE1 GLN A 264 3.738 -16.680 -15.789 1.00 21.71 O ANISOU 583 OE1 GLN A 264 2645 2788 2813 0 -41 35 O ATOM 584 NE2 GLN A 264 5.723 -17.542 -16.383 1.00 20.53 N ANISOU 584 NE2 GLN A 264 2606 2631 2563 6 -22 4 N ATOM 585 N ASP A 265 5.517 -10.700 -15.700 1.00 16.48 N ANISOU 585 N ASP A 265 2094 2089 2079 -6 31 14 N ATOM 586 CA ASP A 265 5.357 -9.505 -16.528 1.00 16.66 C ANISOU 586 CA ASP A 265 2117 2099 2111 4 0 5 C ATOM 587 C ASP A 265 6.063 -8.287 -15.918 1.00 16.13 C ANISOU 587 C ASP A 265 2036 2031 2061 -2 15 25 C ATOM 588 O ASP A 265 5.581 -7.714 -14.951 1.00 16.06 O ANISOU 588 O ASP A 265 2063 2033 2003 -34 -40 23 O ATOM 589 CB ASP A 265 3.877 -9.185 -16.716 1.00 16.99 C ANISOU 589 CB ASP A 265 2132 2169 2151 -16 4 -3 C ATOM 590 CG ASP A 265 3.666 -7.870 -17.427 1.00 18.59 C ANISOU 590 CG ASP A 265 2423 2312 2326 24 -8 16 C ATOM 591 OD1 ASP A 265 4.570 -7.466 -18.179 1.00 20.79 O ANISOU 591 OD1 ASP A 265 2599 2632 2667 -42 67 68 O ATOM 592 OD2 ASP A 265 2.653 -7.157 -17.283 1.00 20.97 O ANISOU 592 OD2 ASP A 265 2512 2659 2794 46 -54 26 O ATOM 593 N PRO A 266 7.191 -7.870 -16.486 1.00 16.10 N ANISOU 593 N PRO A 266 2043 2019 2055 4 2 20 N ATOM 594 CA PRO A 266 7.938 -6.738 -15.926 1.00 15.70 C ANISOU 594 CA PRO A 266 1979 1990 1995 3 14 23 C ATOM 595 C PRO A 266 7.148 -5.423 -15.933 1.00 15.43 C ANISOU 595 C PRO A 266 1960 1952 1949 -4 22 12 C ATOM 596 O PRO A 266 7.485 -4.508 -15.185 1.00 15.85 O ANISOU 596 O PRO A 266 2008 1943 2069 -33 18 48 O ATOM 597 CB PRO A 266 9.160 -6.648 -16.846 1.00 15.94 C ANISOU 597 CB PRO A 266 2002 2013 2041 -1 19 16 C ATOM 598 CG PRO A 266 8.723 -7.272 -18.086 1.00 16.20 C ANISOU 598 CG PRO A 266 2021 2055 2080 -8 0 41 C ATOM 599 CD PRO A 266 7.867 -8.427 -17.670 1.00 16.16 C ANISOU 599 CD PRO A 266 2038 2015 2085 4 14 27 C ATOM 600 N SER A 267 6.100 -5.353 -16.748 1.00 14.97 N ANISOU 600 N SER A 267 1891 1887 1907 10 33 36 N ATOM 601 CA SER A 267 5.258 -4.163 -16.845 1.00 14.82 C ANISOU 601 CA SER A 267 1871 1863 1896 11 31 22 C ATOM 602 C SER A 267 4.241 -4.049 -15.693 1.00 14.14 C ANISOU 602 C SER A 267 1797 1752 1822 3 8 18 C ATOM 603 O SER A 267 3.688 -2.973 -15.440 1.00 14.18 O ANISOU 603 O SER A 267 1747 1709 1929 -1 67 81 O ATOM 604 CB SER A 267 4.529 -4.186 -18.185 1.00 14.88 C ANISOU 604 CB SER A 267 1922 1879 1851 20 15 23 C ATOM 605 OG SER A 267 5.442 -4.458 -19.250 1.00 17.19 O ANISOU 605 OG SER A 267 2145 2209 2174 93 38 36 O ATOM 606 N THR A 268 4.002 -5.148 -14.986 1.00 13.27 N ANISOU 606 N THR A 268 1673 1655 1713 -9 9 18 N ATOM 607 CA THR A 268 3.071 -5.143 -13.865 1.00 12.86 C ANISOU 607 CA THR A 268 1636 1618 1629 0 -10 13 C ATOM 608 C THR A 268 3.802 -4.832 -12.576 1.00 12.19 C ANISOU 608 C THR A 268 1535 1512 1583 -8 -1 32 C ATOM 609 O THR A 268 4.814 -5.450 -12.284 1.00 13.45 O ANISOU 609 O THR A 268 1661 1749 1697 10 -68 66 O ATOM 610 CB THR A 268 2.402 -6.514 -13.713 1.00 13.09 C ANISOU 610 CB THR A 268 1651 1637 1682 -11 4 16 C ATOM 611 OG1 THR A 268 1.835 -6.927 -14.960 1.00 14.86 O ANISOU 611 OG1 THR A 268 1904 1934 1809 -18 -31 38 O ATOM 612 CG2 THR A 268 1.216 -6.436 -12.771 1.00 13.46 C ANISOU 612 CG2 THR A 268 1733 1682 1695 22 8 -23 C ATOM 613 N GLY A 269 3.277 -3.900 -11.802 1.00 11.30 N ANISOU 613 N GLY A 269 1434 1461 1398 -29 3 56 N ATOM 614 CA GLY A 269 3.889 -3.515 -10.547 1.00 10.80 C ANISOU 614 CA GLY A 269 1393 1340 1371 -16 23 32 C ATOM 615 C GLY A 269 3.551 -4.443 -9.393 1.00 9.94 C ANISOU 615 C GLY A 269 1307 1209 1258 14 0 9 C ATOM 616 O GLY A 269 2.927 -5.490 -9.592 1.00 9.80 O ANISOU 616 O GLY A 269 1176 1290 1255 -52 21 41 O ATOM 617 N CYS A 270 3.941 -4.024 -8.188 1.00 9.41 N ANISOU 617 N CYS A 270 1210 1163 1201 22 -20 28 N ATOM 618 CA CYS A 270 3.759 -4.800 -6.965 1.00 9.13 C ANISOU 618 CA CYS A 270 1136 1160 1172 18 19 12 C ATOM 619 C CYS A 270 2.740 -4.129 -6.048 1.00 8.59 C ANISOU 619 C CYS A 270 1060 1087 1113 -18 -11 23 C ATOM 620 O CYS A 270 3.051 -3.171 -5.360 1.00 8.59 O ANISOU 620 O CYS A 270 1006 1043 1214 -2 46 23 O ATOM 621 CB CYS A 270 5.094 -4.939 -6.241 1.00 8.93 C ANISOU 621 CB CYS A 270 1130 1118 1145 -49 13 40 C ATOM 622 SG CYS A 270 6.301 -5.890 -7.187 1.00 11.78 S ANISOU 622 SG CYS A 270 1162 1786 1526 163 -104 -51 S ATOM 623 N TYR A 271 1.534 -4.689 -6.027 1.00 7.72 N ANISOU 623 N TYR A 271 865 985 1080 -23 17 87 N ATOM 624 CA TYR A 271 0.395 -4.088 -5.335 1.00 7.49 C ANISOU 624 CA TYR A 271 962 926 956 31 10 8 C ATOM 625 C TYR A 271 -0.319 -5.032 -4.371 1.00 7.81 C ANISOU 625 C TYR A 271 890 993 1082 10 47 36 C ATOM 626 O TYR A 271 -1.458 -4.765 -3.984 1.00 9.56 O ANISOU 626 O TYR A 271 1064 1228 1338 134 177 142 O ATOM 627 CB TYR A 271 -0.632 -3.568 -6.342 1.00 7.33 C ANISOU 627 CB TYR A 271 935 881 967 -22 38 12 C ATOM 628 CG TYR A 271 -0.135 -2.471 -7.251 1.00 6.27 C ANISOU 628 CG TYR A 271 713 818 848 36 -6 8 C ATOM 629 CD1 TYR A 271 0.436 -2.755 -8.470 1.00 7.19 C ANISOU 629 CD1 TYR A 271 890 984 857 -6 -51 -16 C ATOM 630 CD2 TYR A 271 -0.226 -1.140 -6.869 1.00 6.27 C ANISOU 630 CD2 TYR A 271 640 872 868 20 -18 -52 C ATOM 631 CE1 TYR A 271 0.908 -1.730 -9.296 1.00 8.82 C ANISOU 631 CE1 TYR A 271 1134 1086 1128 -105 -9 7 C ATOM 632 CE2 TYR A 271 0.215 -0.129 -7.682 1.00 8.69 C ANISOU 632 CE2 TYR A 271 1096 1006 1199 35 18 110 C ATOM 633 CZ TYR A 271 0.779 -0.422 -8.900 1.00 10.07 C ANISOU 633 CZ TYR A 271 1369 1184 1271 37 95 73 C ATOM 634 OH TYR A 271 1.264 0.593 -9.736 1.00 11.34 O ANISOU 634 OH TYR A 271 1564 1316 1427 -47 176 189 O ATOM 635 N MET A 272 0.318 -6.126 -3.978 1.00 7.16 N ANISOU 635 N MET A 272 860 960 901 33 4 51 N ATOM 636 CA MET A 272 -0.293 -7.082 -3.043 1.00 7.14 C ANISOU 636 CA MET A 272 846 926 940 -10 6 0 C ATOM 637 C MET A 272 -0.032 -6.699 -1.597 1.00 6.56 C ANISOU 637 C MET A 272 727 908 857 -14 -5 12 C ATOM 638 O MET A 272 1.097 -6.443 -1.231 1.00 8.45 O ANISOU 638 O MET A 272 862 1343 1005 -98 -15 -71 O ATOM 639 CB MET A 272 0.278 -8.463 -3.298 1.00 8.45 C ANISOU 639 CB MET A 272 1045 1005 1159 -26 -31 3 C ATOM 640 CG MET A 272 0.302 -8.779 -4.721 1.00 11.16 C ANISOU 640 CG MET A 272 1576 1315 1348 -4 141 4 C ATOM 641 SD MET A 272 -1.313 -9.170 -5.314 1.00 16.65 S ANISOU 641 SD MET A 272 2094 2129 2101 111 -88 52 S ATOM 642 CE MET A 272 -1.431 -10.923 -4.854 1.00 15.19 C ANISOU 642 CE MET A 272 1924 1937 1908 -10 -1 -50 C ATOM 643 N TYR A 273 -1.069 -6.720 -0.762 1.00 4.99 N ANISOU 643 N TYR A 273 588 716 589 4 -30 0 N ATOM 644 CA TYR A 273 -0.965 -6.317 0.636 1.00 4.07 C ANISOU 644 CA TYR A 273 451 528 564 -12 -38 -32 C ATOM 645 C TYR A 273 -1.528 -7.438 1.507 1.00 3.83 C ANISOU 645 C TYR A 273 414 534 507 -7 -51 0 C ATOM 646 O TYR A 273 -2.742 -7.637 1.586 1.00 3.34 O ANISOU 646 O TYR A 273 309 398 562 11 -21 69 O ATOM 647 CB TYR A 273 -1.728 -4.999 0.851 1.00 4.11 C ANISOU 647 CB TYR A 273 572 472 516 -23 -56 15 C ATOM 648 CG TYR A 273 -1.227 -4.132 1.999 1.00 4.58 C ANISOU 648 CG TYR A 273 518 617 602 59 -69 -67 C ATOM 649 CD1 TYR A 273 -1.357 -2.759 1.935 1.00 4.48 C ANISOU 649 CD1 TYR A 273 470 614 616 90 -71 13 C ATOM 650 CD2 TYR A 273 -0.633 -4.674 3.136 1.00 4.40 C ANISOU 650 CD2 TYR A 273 599 574 497 29 0 -16 C ATOM 651 CE1 TYR A 273 -0.927 -1.952 2.925 1.00 4.77 C ANISOU 651 CE1 TYR A 273 662 535 612 -15 -21 34 C ATOM 652 CE2 TYR A 273 -0.163 -3.845 4.139 1.00 4.02 C ANISOU 652 CE2 TYR A 273 647 505 376 -50 -18 93 C ATOM 653 CZ TYR A 273 -0.324 -2.484 4.029 1.00 4.65 C ANISOU 653 CZ TYR A 273 637 573 556 -6 -75 -56 C ATOM 654 OH TYR A 273 0.118 -1.614 5.013 1.00 7.52 O ANISOU 654 OH TYR A 273 1035 986 835 -165 -50 -164 O ATOM 655 N TYR A 274 -0.636 -8.180 2.154 1.00 3.98 N ANISOU 655 N TYR A 274 420 470 619 18 3 52 N ATOM 656 CA TYR A 274 -1.005 -9.319 2.970 1.00 3.83 C ANISOU 656 CA TYR A 274 406 531 515 -18 -24 11 C ATOM 657 C TYR A 274 -1.286 -8.878 4.395 1.00 3.61 C ANISOU 657 C TYR A 274 398 473 500 -14 -14 9 C ATOM 658 O TYR A 274 -0.648 -7.961 4.910 1.00 4.54 O ANISOU 658 O TYR A 274 561 624 540 -125 -52 -63 O ATOM 659 CB TYR A 274 0.138 -10.339 2.981 1.00 4.11 C ANISOU 659 CB TYR A 274 447 537 574 -13 -19 89 C ATOM 660 CG TYR A 274 0.388 -11.053 1.676 1.00 4.96 C ANISOU 660 CG TYR A 274 513 696 674 -15 -28 -23 C ATOM 661 CD1 TYR A 274 1.246 -10.526 0.719 1.00 5.36 C ANISOU 661 CD1 TYR A 274 650 700 683 -120 -71 19 C ATOM 662 CD2 TYR A 274 -0.224 -12.265 1.396 1.00 5.30 C ANISOU 662 CD2 TYR A 274 739 616 658 -18 -79 12 C ATOM 663 CE1 TYR A 274 1.490 -11.188 -0.479 1.00 6.70 C ANISOU 663 CE1 TYR A 274 813 965 767 31 59 10 C ATOM 664 CE2 TYR A 274 0.006 -12.940 0.195 1.00 6.92 C ANISOU 664 CE2 TYR A 274 857 1007 765 33 -4 -2 C ATOM 665 CZ TYR A 274 0.870 -12.395 -0.739 1.00 6.97 C ANISOU 665 CZ TYR A 274 921 950 775 7 -34 31 C ATOM 666 OH TYR A 274 1.100 -13.077 -1.933 1.00 9.55 O ANISOU 666 OH TYR A 274 1225 1416 986 44 -113 -97 O ATOM 667 N PHE A 275 -2.204 -9.577 5.053 1.00 3.13 N ANISOU 667 N PHE A 275 390 361 436 -41 28 11 N ATOM 668 CA PHE A 275 -2.584 -9.269 6.430 1.00 3.02 C ANISOU 668 CA PHE A 275 353 379 412 -41 -15 -27 C ATOM 669 C PHE A 275 -3.304 -10.460 7.058 1.00 3.36 C ANISOU 669 C PHE A 275 427 397 452 3 17 -22 C ATOM 670 O PHE A 275 -3.810 -11.339 6.363 1.00 2.97 O ANISOU 670 O PHE A 275 269 419 440 -42 48 -70 O ATOM 671 CB PHE A 275 -3.479 -8.019 6.491 1.00 3.74 C ANISOU 671 CB PHE A 275 482 455 481 6 62 -39 C ATOM 672 CG PHE A 275 -4.842 -8.196 5.877 1.00 3.41 C ANISOU 672 CG PHE A 275 466 275 553 19 14 -12 C ATOM 673 CD1 PHE A 275 -5.938 -8.500 6.671 1.00 3.55 C ANISOU 673 CD1 PHE A 275 437 540 373 80 1 -100 C ATOM 674 CD2 PHE A 275 -5.041 -8.040 4.501 1.00 3.27 C ANISOU 674 CD2 PHE A 275 276 416 548 -34 26 -6 C ATOM 675 CE1 PHE A 275 -7.221 -8.664 6.107 1.00 4.70 C ANISOU 675 CE1 PHE A 275 571 640 575 35 -81 22 C ATOM 676 CE2 PHE A 275 -6.309 -8.195 3.945 1.00 4.03 C ANISOU 676 CE2 PHE A 275 511 597 421 130 -69 102 C ATOM 677 CZ PHE A 275 -7.394 -8.516 4.739 1.00 4.62 C ANISOU 677 CZ PHE A 275 576 644 534 59 2 16 C ATOM 678 N GLN A 276 -3.367 -10.452 8.380 1.00 4.50 N ANISOU 678 N GLN A 276 614 548 546 19 22 -5 N ATOM 679 CA GLN A 276 -4.010 -11.514 9.136 1.00 5.09 C ANISOU 679 CA GLN A 276 664 612 657 -25 3 -11 C ATOM 680 C GLN A 276 -5.407 -11.053 9.565 1.00 5.20 C ANISOU 680 C GLN A 276 714 597 665 -15 19 -16 C ATOM 681 O GLN A 276 -5.594 -9.913 10.001 1.00 5.72 O ANISOU 681 O GLN A 276 737 584 849 86 26 -2 O ATOM 682 CB GLN A 276 -3.151 -11.888 10.361 1.00 5.88 C ANISOU 682 CB GLN A 276 870 664 698 -21 16 31 C ATOM 683 CG GLN A 276 -1.806 -12.577 10.022 1.00 9.43 C ANISOU 683 CG GLN A 276 1137 1169 1275 27 1 17 C ATOM 684 CD GLN A 276 -0.956 -12.903 11.254 1.00 12.98 C ANISOU 684 CD GLN A 276 1699 1699 1533 65 -75 -2 C ATOM 685 OE1 GLN A 276 -1.390 -13.651 12.130 1.00 16.67 O ANISOU 685 OE1 GLN A 276 2311 2012 2011 -40 103 73 O ATOM 686 NE2 GLN A 276 0.255 -12.348 11.315 1.00 15.60 N ANISOU 686 NE2 GLN A 276 1927 1998 2001 -32 71 -55 N ATOM 687 N TYR A 277 -6.384 -11.944 9.452 1.00 5.26 N ANISOU 687 N TYR A 277 638 645 714 -4 27 -12 N ATOM 688 CA TYR A 277 -7.744 -11.651 9.898 1.00 5.66 C ANISOU 688 CA TYR A 277 715 708 726 4 23 -4 C ATOM 689 C TYR A 277 -8.393 -12.961 10.353 1.00 5.91 C ANISOU 689 C TYR A 277 743 723 778 17 7 20 C ATOM 690 O TYR A 277 -8.426 -13.930 9.604 1.00 5.37 O ANISOU 690 O TYR A 277 658 696 685 44 -11 -2 O ATOM 691 CB TYR A 277 -8.558 -11.016 8.774 1.00 5.90 C ANISOU 691 CB TYR A 277 808 665 767 -5 46 66 C ATOM 692 CG TYR A 277 -9.979 -10.691 9.138 1.00 7.85 C ANISOU 692 CG TYR A 277 959 1003 1018 31 3 48 C ATOM 693 CD1 TYR A 277 -10.279 -9.822 10.198 1.00 9.54 C ANISOU 693 CD1 TYR A 277 1229 1129 1266 10 7 6 C ATOM 694 CD2 TYR A 277 -11.030 -11.267 8.443 1.00 9.98 C ANISOU 694 CD2 TYR A 277 1225 1201 1363 -16 -31 -32 C ATOM 695 CE1 TYR A 277 -11.610 -9.537 10.537 1.00 11.31 C ANISOU 695 CE1 TYR A 277 1457 1409 1428 121 55 -10 C ATOM 696 CE2 TYR A 277 -12.344 -10.987 8.771 1.00 10.76 C ANISOU 696 CE2 TYR A 277 1220 1388 1480 22 -16 3 C ATOM 697 CZ TYR A 277 -12.630 -10.122 9.815 1.00 11.66 C ANISOU 697 CZ TYR A 277 1445 1456 1530 20 32 1 C ATOM 698 OH TYR A 277 -13.964 -9.861 10.117 1.00 14.70 O ANISOU 698 OH TYR A 277 1559 1923 2102 109 -61 -28 O ATOM 699 N LEU A 278 -8.887 -12.991 11.585 1.00 7.15 N ANISOU 699 N LEU A 278 891 915 910 56 26 0 N ATOM 700 CA LEU A 278 -9.584 -14.175 12.104 1.00 8.43 C ANISOU 700 CA LEU A 278 1080 1041 1082 20 22 11 C ATOM 701 C LEU A 278 -8.816 -15.474 11.862 1.00 8.45 C ANISOU 701 C LEU A 278 1101 1050 1059 25 0 17 C ATOM 702 O LEU A 278 -9.363 -16.436 11.328 1.00 8.91 O ANISOU 702 O LEU A 278 1098 1156 1130 59 -31 -27 O ATOM 703 CB LEU A 278 -10.963 -14.309 11.460 1.00 9.05 C ANISOU 703 CB LEU A 278 1148 1126 1162 -3 22 10 C ATOM 704 CG LEU A 278 -11.888 -13.101 11.549 1.00 11.31 C ANISOU 704 CG LEU A 278 1403 1375 1518 52 33 22 C ATOM 705 CD1 LEU A 278 -13.254 -13.456 10.996 1.00 12.77 C ANISOU 705 CD1 LEU A 278 1575 1588 1686 4 -40 -18 C ATOM 706 CD2 LEU A 278 -11.991 -12.641 12.981 1.00 12.89 C ANISOU 706 CD2 LEU A 278 1617 1643 1636 71 -36 -66 C ATOM 707 N SER A 279 -7.550 -15.485 12.238 1.00 8.16 N ANISOU 707 N SER A 279 1039 1068 993 23 35 31 N ATOM 708 CA SER A 279 -6.726 -16.699 12.189 1.00 8.34 C ANISOU 708 CA SER A 279 1072 1063 1033 41 -1 -15 C ATOM 709 C SER A 279 -6.327 -17.162 10.800 1.00 7.27 C ANISOU 709 C SER A 279 926 908 927 23 18 19 C ATOM 710 O SER A 279 -5.822 -18.268 10.642 1.00 7.53 O ANISOU 710 O SER A 279 939 976 946 92 44 58 O ATOM 711 CB SER A 279 -7.408 -17.842 12.930 1.00 9.09 C ANISOU 711 CB SER A 279 1147 1178 1125 63 16 12 C ATOM 712 OG SER A 279 -7.485 -17.549 14.313 1.00 11.57 O ANISOU 712 OG SER A 279 1511 1558 1327 57 -6 -118 O ATOM 713 N LYS A 280 -6.564 -16.331 9.794 1.00 6.03 N ANISOU 713 N LYS A 280 713 774 803 9 40 -2 N ATOM 714 CA LYS A 280 -6.140 -16.648 8.438 1.00 6.02 C ANISOU 714 CA LYS A 280 765 734 788 0 21 -10 C ATOM 715 C LYS A 280 -5.421 -15.467 7.814 1.00 4.54 C ANISOU 715 C LYS A 280 543 577 604 27 12 -41 C ATOM 716 O LYS A 280 -5.519 -14.349 8.304 1.00 4.95 O ANISOU 716 O LYS A 280 596 568 714 -51 67 -61 O ATOM 717 CB LYS A 280 -7.330 -17.020 7.577 1.00 7.25 C ANISOU 717 CB LYS A 280 872 981 900 60 -11 -54 C ATOM 718 CG LYS A 280 -7.994 -18.319 7.980 1.00 9.89 C ANISOU 718 CG LYS A 280 1249 1266 1241 -36 17 20 C ATOM 719 CD LYS A 280 -7.131 -19.538 7.632 1.00 12.93 C ANISOU 719 CD LYS A 280 1644 1635 1632 106 61 18 C ATOM 720 CE LYS A 280 -7.931 -20.831 7.578 1.00 14.90 C ANISOU 720 CE LYS A 280 1882 1869 1908 7 -22 -42 C ATOM 721 NZ LYS A 280 -8.998 -20.859 6.529 1.00 16.86 N ANISOU 721 NZ LYS A 280 2125 2239 2041 79 -101 -25 N ATOM 722 N THR A 281 -4.718 -15.736 6.721 1.00 3.26 N ANISOU 722 N THR A 281 403 424 409 -7 -6 -15 N ATOM 723 CA THR A 281 -4.000 -14.721 5.981 1.00 2.85 C ANISOU 723 CA THR A 281 376 368 339 28 -26 -20 C ATOM 724 C THR A 281 -4.760 -14.419 4.712 1.00 2.66 C ANISOU 724 C THR A 281 300 396 312 -16 -40 -42 C ATOM 725 O THR A 281 -5.177 -15.333 3.985 1.00 2.70 O ANISOU 725 O THR A 281 376 345 304 -10 -46 -51 O ATOM 726 CB THR A 281 -2.601 -15.190 5.609 1.00 2.80 C ANISOU 726 CB THR A 281 361 386 316 0 -40 -28 C ATOM 727 OG1 THR A 281 -1.835 -15.409 6.799 1.00 3.75 O ANISOU 727 OG1 THR A 281 504 431 490 112 -147 -16 O ATOM 728 CG2 THR A 281 -1.850 -14.108 4.845 1.00 3.77 C ANISOU 728 CG2 THR A 281 463 559 407 21 -14 9 C ATOM 729 N TYR A 282 -4.959 -13.135 4.484 1.00 2.91 N ANISOU 729 N TYR A 282 361 413 330 -15 -46 -88 N ATOM 730 CA TYR A 282 -5.619 -12.626 3.305 1.00 3.71 C ANISOU 730 CA TYR A 282 445 480 481 17 -65 -18 C ATOM 731 C TYR A 282 -4.710 -11.621 2.613 1.00 3.92 C ANISOU 731 C TYR A 282 449 508 532 7 -80 -29 C ATOM 732 O TYR A 282 -3.640 -11.275 3.125 1.00 3.68 O ANISOU 732 O TYR A 282 400 535 463 -69 -129 32 O ATOM 733 CB TYR A 282 -6.939 -11.960 3.695 1.00 4.97 C ANISOU 733 CB TYR A 282 567 679 640 50 -41 -47 C ATOM 734 CG TYR A 282 -7.926 -12.915 4.286 1.00 6.85 C ANISOU 734 CG TYR A 282 752 915 933 20 -6 14 C ATOM 735 CD1 TYR A 282 -8.671 -13.751 3.478 1.00 9.02 C ANISOU 735 CD1 TYR A 282 1100 1256 1069 -55 -57 -56 C ATOM 736 CD2 TYR A 282 -8.104 -13.000 5.655 1.00 8.58 C ANISOU 736 CD2 TYR A 282 1044 1169 1046 57 -44 -42 C ATOM 737 CE1 TYR A 282 -9.591 -14.640 4.023 1.00 10.17 C ANISOU 737 CE1 TYR A 282 1167 1375 1321 -117 -7 -25 C ATOM 738 CE2 TYR A 282 -8.989 -13.866 6.207 1.00 9.85 C ANISOU 738 CE2 TYR A 282 1185 1352 1206 1 11 -50 C ATOM 739 CZ TYR A 282 -9.744 -14.696 5.394 1.00 10.53 C ANISOU 739 CZ TYR A 282 1314 1362 1323 -82 -28 -51 C ATOM 740 OH TYR A 282 -10.649 -15.569 5.963 1.00 12.92 O ANISOU 740 OH TYR A 282 1494 1813 1599 -107 127 -34 O ATOM 741 N CYS A 283 -5.143 -11.162 1.455 1.00 3.99 N ANISOU 741 N CYS A 283 489 568 456 -10 -42 -8 N ATOM 742 CA CYS A 283 -4.385 -10.231 0.678 1.00 4.67 C ANISOU 742 CA CYS A 283 570 588 616 24 -74 8 C ATOM 743 C CYS A 283 -5.334 -9.326 -0.074 1.00 4.71 C ANISOU 743 C CYS A 283 558 638 593 14 -78 24 C ATOM 744 O CYS A 283 -6.343 -9.789 -0.597 1.00 5.07 O ANISOU 744 O CYS A 283 625 561 740 -19 -108 -8 O ATOM 745 CB CYS A 283 -3.520 -10.990 -0.317 1.00 5.60 C ANISOU 745 CB CYS A 283 665 781 679 36 -62 -53 C ATOM 746 SG CYS A 283 -2.442 -9.998 -1.346 1.00 9.64 S ANISOU 746 SG CYS A 283 1151 1280 1230 -14 146 -40 S ATOM 747 N VAL A 284 -5.013 -8.038 -0.087 1.00 4.72 N ANISOU 747 N VAL A 284 574 619 600 -3 -54 30 N ATOM 748 CA VAL A 284 -5.717 -7.108 -0.955 1.00 5.09 C ANISOU 748 CA VAL A 284 604 668 658 30 -54 43 C ATOM 749 C VAL A 284 -4.863 -6.956 -2.187 1.00 5.41 C ANISOU 749 C VAL A 284 580 671 802 6 -36 61 C ATOM 750 O VAL A 284 -3.748 -6.457 -2.108 1.00 6.13 O ANISOU 750 O VAL A 284 616 782 930 -77 -54 80 O ATOM 751 CB VAL A 284 -5.968 -5.744 -0.338 1.00 5.06 C ANISOU 751 CB VAL A 284 594 612 713 0 -76 84 C ATOM 752 CG1 VAL A 284 -6.655 -4.824 -1.344 1.00 5.89 C ANISOU 752 CG1 VAL A 284 703 757 777 91 -60 70 C ATOM 753 CG2 VAL A 284 -6.779 -5.865 0.880 1.00 7.11 C ANISOU 753 CG2 VAL A 284 919 893 887 67 2 21 C ATOM 754 N ASP A 285 -5.394 -7.385 -3.319 1.00 5.71 N ANISOU 754 N ASP A 285 660 740 767 48 1 37 N ATOM 755 CA ASP A 285 -4.666 -7.337 -4.568 1.00 5.90 C ANISOU 755 CA ASP A 285 691 796 755 31 -4 54 C ATOM 756 C ASP A 285 -5.113 -6.111 -5.342 1.00 5.82 C ANISOU 756 C ASP A 285 703 763 743 -4 12 50 C ATOM 757 O ASP A 285 -6.190 -6.108 -5.949 1.00 6.32 O ANISOU 757 O ASP A 285 795 794 811 -13 44 90 O ATOM 758 CB ASP A 285 -4.905 -8.614 -5.357 1.00 6.16 C ANISOU 758 CB ASP A 285 704 857 777 55 0 51 C ATOM 759 CG ASP A 285 -4.259 -8.595 -6.721 1.00 7.21 C ANISOU 759 CG ASP A 285 895 951 893 4 -3 37 C ATOM 760 OD1 ASP A 285 -3.614 -7.579 -7.077 1.00 8.80 O ANISOU 760 OD1 ASP A 285 1164 1066 1111 32 157 106 O ATOM 761 OD2 ASP A 285 -4.322 -9.591 -7.461 1.00 7.27 O ANISOU 761 OD2 ASP A 285 1085 914 762 51 146 89 O ATOM 762 N ALA A 286 -4.283 -5.074 -5.311 1.00 6.66 N ANISOU 762 N ALA A 286 784 852 894 -7 -39 49 N ATOM 763 CA ALA A 286 -4.629 -3.814 -5.964 1.00 6.76 C ANISOU 763 CA ALA A 286 838 845 882 -6 -28 64 C ATOM 764 C ALA A 286 -3.882 -3.634 -7.296 1.00 7.12 C ANISOU 764 C ALA A 286 842 892 970 3 9 49 C ATOM 765 O ALA A 286 -3.616 -2.510 -7.724 1.00 7.92 O ANISOU 765 O ALA A 286 1089 848 1070 59 30 153 O ATOM 766 CB ALA A 286 -4.407 -2.639 -5.017 1.00 6.56 C ANISOU 766 CB ALA A 286 815 778 898 5 61 73 C ATOM 767 N THR A 287 -3.555 -4.735 -7.955 1.00 7.49 N ANISOU 767 N THR A 287 944 940 960 -3 4 51 N ATOM 768 CA THR A 287 -2.744 -4.680 -9.174 1.00 8.19 C ANISOU 768 CA THR A 287 1056 1016 1038 1 42 40 C ATOM 769 C THR A 287 -3.449 -4.007 -10.323 1.00 8.84 C ANISOU 769 C THR A 287 1148 1113 1096 -5 39 50 C ATOM 770 O THR A 287 -2.826 -3.251 -11.081 1.00 10.22 O ANISOU 770 O THR A 287 1366 1213 1303 -18 126 157 O ATOM 771 CB THR A 287 -2.300 -6.078 -9.564 1.00 7.83 C ANISOU 771 CB THR A 287 1020 1010 944 -8 39 0 C ATOM 772 OG1 THR A 287 -1.557 -6.633 -8.479 1.00 8.73 O ANISOU 772 OG1 THR A 287 1024 1019 1273 35 29 92 O ATOM 773 CG2 THR A 287 -1.318 -6.067 -10.731 1.00 8.72 C ANISOU 773 CG2 THR A 287 1076 1082 1153 -4 87 77 C ATOM 774 N ARG A 288 -4.736 -4.266 -10.464 1.00 9.65 N ANISOU 774 N ARG A 288 1257 1214 1193 6 -25 35 N ATOM 775 CA ARG A 288 -5.477 -3.654 -11.562 1.00 10.73 C ANISOU 775 CA ARG A 288 1396 1358 1321 -1 -21 41 C ATOM 776 C ARG A 288 -5.526 -2.121 -11.436 1.00 10.38 C ANISOU 776 C ARG A 288 1347 1335 1261 3 -10 11 C ATOM 777 O ARG A 288 -5.727 -1.585 -10.345 1.00 10.08 O ANISOU 777 O ARG A 288 1306 1278 1243 -23 -32 20 O ATOM 778 CB ARG A 288 -6.881 -4.212 -11.625 1.00 12.06 C ANISOU 778 CB ARG A 288 1510 1543 1529 -20 -3 33 C ATOM 779 CG ARG A 288 -7.583 -3.784 -12.884 1.00 15.68 C ANISOU 779 CG ARG A 288 2076 1983 1897 -5 -98 62 C ATOM 780 CD ARG A 288 -9.021 -3.465 -12.682 1.00 20.51 C ANISOU 780 CD ARG A 288 2471 2644 2678 100 43 2 C ATOM 781 NE ARG A 288 -9.781 -4.580 -12.135 1.00 23.51 N ANISOU 781 NE ARG A 288 3008 2892 3030 -80 8 68 N ATOM 782 CZ ARG A 288 -10.953 -4.433 -11.541 1.00 27.23 C ANISOU 782 CZ ARG A 288 3337 3490 3517 23 95 2 C ATOM 783 NH1 ARG A 288 -11.478 -3.214 -11.424 1.00 28.82 N ANISOU 783 NH1 ARG A 288 3636 3555 3759 13 21 -1 N ATOM 784 NH2 ARG A 288 -11.608 -5.491 -11.067 1.00 28.28 N ANISOU 784 NH2 ARG A 288 3599 3508 3634 -13 73 17 N ATOM 785 N GLU A 289 -5.341 -1.432 -12.564 1.00 10.37 N ANISOU 785 N GLU A 289 1326 1330 1281 -13 13 42 N ATOM 786 CA GLU A 289 -5.381 0.023 -12.601 1.00 10.71 C ANISOU 786 CA GLU A 289 1367 1383 1317 13 18 14 C ATOM 787 C GLU A 289 -6.838 0.472 -12.472 1.00 10.95 C ANISOU 787 C GLU A 289 1380 1421 1358 27 -26 14 C ATOM 788 O GLU A 289 -7.684 0.144 -13.309 1.00 12.32 O ANISOU 788 O GLU A 289 1527 1621 1530 51 -52 -47 O ATOM 789 CB GLU A 289 -4.738 0.570 -13.893 1.00 10.63 C ANISOU 789 CB GLU A 289 1334 1377 1327 18 22 10 C ATOM 790 CG GLU A 289 -3.210 0.485 -13.935 1.00 11.00 C ANISOU 790 CG GLU A 289 1351 1483 1343 6 60 55 C ATOM 791 CD GLU A 289 -2.480 1.416 -12.968 1.00 12.44 C ANISOU 791 CD GLU A 289 1502 1605 1617 0 -9 -40 C ATOM 792 OE1 GLU A 289 -2.981 2.528 -12.664 1.00 12.00 O ANISOU 792 OE1 GLU A 289 1251 1648 1659 -42 27 -13 O ATOM 793 OE2 GLU A 289 -1.356 1.049 -12.513 1.00 13.85 O ANISOU 793 OE2 GLU A 289 1658 1896 1705 94 24 133 O ATOM 794 N THR A 290 -7.131 1.159 -11.375 1.00 11.40 N ANISOU 794 N THR A 290 1438 1502 1390 54 -26 28 N ATOM 795 CA THR A 290 -8.449 1.727 -11.099 1.00 11.34 C ANISOU 795 CA THR A 290 1452 1471 1383 27 14 16 C ATOM 796 C THR A 290 -8.245 3.209 -10.787 1.00 11.25 C ANISOU 796 C THR A 290 1473 1464 1337 10 -9 29 C ATOM 797 O THR A 290 -7.125 3.694 -10.808 1.00 11.38 O ANISOU 797 O THR A 290 1561 1502 1259 -22 46 37 O ATOM 798 CB THR A 290 -9.078 1.066 -9.864 1.00 11.50 C ANISOU 798 CB THR A 290 1444 1451 1474 25 19 26 C ATOM 799 OG1 THR A 290 -8.289 1.378 -8.702 1.00 12.81 O ANISOU 799 OG1 THR A 290 1694 1739 1434 66 101 50 O ATOM 800 CG2 THR A 290 -9.081 -0.467 -9.982 1.00 12.13 C ANISOU 800 CG2 THR A 290 1597 1500 1509 39 93 -1 C ATOM 801 N ASN A 291 -9.324 3.912 -10.464 1.00 11.55 N ANISOU 801 N ASN A 291 1477 1515 1395 28 32 54 N ATOM 802 CA ASN A 291 -9.243 5.324 -10.101 1.00 12.32 C ANISOU 802 CA ASN A 291 1576 1553 1549 4 5 4 C ATOM 803 C ASN A 291 -8.919 5.514 -8.617 1.00 11.55 C ANISOU 803 C ASN A 291 1532 1407 1447 12 49 21 C ATOM 804 O ASN A 291 -8.759 6.641 -8.150 1.00 12.19 O ANISOU 804 O ASN A 291 1708 1386 1534 15 65 26 O ATOM 805 CB ASN A 291 -10.570 6.060 -10.380 1.00 13.56 C ANISOU 805 CB ASN A 291 1685 1659 1806 48 -3 12 C ATOM 806 CG ASN A 291 -10.959 6.089 -11.845 1.00 17.35 C ANISOU 806 CG ASN A 291 2284 2167 2140 6 -27 8 C ATOM 807 OD1 ASN A 291 -10.110 6.120 -12.733 1.00 22.60 O ANISOU 807 OD1 ASN A 291 2813 2910 2862 16 260 75 O ATOM 808 ND2 ASN A 291 -12.262 6.117 -12.105 1.00 20.14 N ANISOU 808 ND2 ASN A 291 2343 2560 2745 38 -26 33 N ATOM 809 N ARG A 292 -8.774 4.417 -7.878 1.00 10.55 N ANISOU 809 N ARG A 292 1360 1316 1331 31 10 6 N ATOM 810 CA ARG A 292 -8.568 4.494 -6.433 1.00 9.58 C ANISOU 810 CA ARG A 292 1205 1199 1233 8 -7 -29 C ATOM 811 C ARG A 292 -7.148 4.925 -6.076 1.00 8.76 C ANISOU 811 C ARG A 292 1092 1122 1113 13 25 -34 C ATOM 812 O ARG A 292 -6.179 4.470 -6.683 1.00 9.13 O ANISOU 812 O ARG A 292 1134 1148 1186 35 50 -87 O ATOM 813 CB ARG A 292 -8.871 3.133 -5.814 1.00 10.34 C ANISOU 813 CB ARG A 292 1352 1291 1285 -44 -32 5 C ATOM 814 CG ARG A 292 -10.310 2.725 -6.011 1.00 12.59 C ANISOU 814 CG ARG A 292 1537 1589 1655 -63 5 28 C ATOM 815 CD ARG A 292 -11.265 3.556 -5.189 1.00 15.23 C ANISOU 815 CD ARG A 292 1864 1847 2072 26 -23 -81 C ATOM 816 NE ARG A 292 -12.506 2.853 -4.920 1.00 17.76 N ANISOU 816 NE ARG A 292 2162 2243 2343 -7 143 4 N ATOM 817 CZ ARG A 292 -13.077 2.758 -3.731 1.00 17.50 C ANISOU 817 CZ ARG A 292 2323 2185 2141 26 10 35 C ATOM 818 NH1 ARG A 292 -12.537 3.326 -2.655 1.00 16.94 N ANISOU 818 NH1 ARG A 292 2113 2054 2268 14 1 -7 N ATOM 819 NH2 ARG A 292 -14.213 2.102 -3.629 1.00 19.54 N ANISOU 819 NH2 ARG A 292 2465 2426 2532 -20 54 36 N ATOM 820 N LEU A 293 -7.025 5.782 -5.071 1.00 7.23 N ANISOU 820 N LEU A 293 833 927 987 -10 8 8 N ATOM 821 CA LEU A 293 -5.735 6.379 -4.748 1.00 7.48 C ANISOU 821 CA LEU A 293 897 949 994 -43 22 4 C ATOM 822 C LEU A 293 -4.840 5.639 -3.756 1.00 6.69 C ANISOU 822 C LEU A 293 781 794 964 -47 37 -17 C ATOM 823 O LEU A 293 -3.620 5.841 -3.723 1.00 6.10 O ANISOU 823 O LEU A 293 619 699 999 -50 55 24 O ATOM 824 CB LEU A 293 -5.979 7.790 -4.210 1.00 8.55 C ANISOU 824 CB LEU A 293 1038 1054 1155 -93 51 -66 C ATOM 825 CG LEU A 293 -6.625 8.772 -5.174 1.00 11.74 C ANISOU 825 CG LEU A 293 1556 1339 1566 -12 38 38 C ATOM 826 CD1 LEU A 293 -6.985 10.050 -4.446 1.00 12.96 C ANISOU 826 CD1 LEU A 293 1712 1548 1662 6 21 -42 C ATOM 827 CD2 LEU A 293 -5.743 9.031 -6.372 1.00 13.89 C ANISOU 827 CD2 LEU A 293 1841 1631 1804 56 122 40 C ATOM 828 N GLY A 294 -5.423 4.802 -2.912 1.00 6.44 N ANISOU 828 N GLY A 294 778 829 837 -19 104 -7 N ATOM 829 CA GLY A 294 -4.650 4.135 -1.894 1.00 6.43 C ANISOU 829 CA GLY A 294 779 805 859 -44 89 -9 C ATOM 830 C GLY A 294 -3.478 3.346 -2.457 1.00 5.14 C ANISOU 830 C GLY A 294 638 643 668 -7 23 0 C ATOM 831 O GLY A 294 -2.388 3.329 -1.888 1.00 5.45 O ANISOU 831 O GLY A 294 657 746 667 -27 0 -80 O ATOM 832 N ARG A 295 -3.697 2.727 -3.604 1.00 4.69 N ANISOU 832 N ARG A 295 537 590 653 -60 -8 -31 N ATOM 833 CA ARG A 295 -2.712 1.877 -4.246 1.00 4.81 C ANISOU 833 CA ARG A 295 559 635 633 -39 -10 -1 C ATOM 834 C ARG A 295 -1.546 2.667 -4.815 1.00 5.49 C ANISOU 834 C ARG A 295 661 669 755 -7 93 10 C ATOM 835 O ARG A 295 -0.539 2.061 -5.192 1.00 6.77 O ANISOU 835 O ARG A 295 700 874 995 18 76 -15 O ATOM 836 CB ARG A 295 -3.373 1.056 -5.358 1.00 4.81 C ANISOU 836 CB ARG A 295 628 599 598 -39 10 -3 C ATOM 837 CG ARG A 295 -4.010 1.884 -6.432 1.00 4.81 C ANISOU 837 CG ARG A 295 636 609 582 67 33 -4 C ATOM 838 CD ARG A 295 -4.737 1.063 -7.458 1.00 5.53 C ANISOU 838 CD ARG A 295 684 644 772 43 31 22 C ATOM 839 NE ARG A 295 -3.898 0.163 -8.234 1.00 5.96 N ANISOU 839 NE ARG A 295 936 528 799 -44 109 -52 N ATOM 840 CZ ARG A 295 -3.250 0.529 -9.333 1.00 7.05 C ANISOU 840 CZ ARG A 295 956 837 884 7 124 -32 C ATOM 841 NH1 ARG A 295 -3.355 1.770 -9.772 1.00 7.49 N ANISOU 841 NH1 ARG A 295 972 919 952 -3 163 86 N ATOM 842 NH2 ARG A 295 -2.531 -0.351 -10.022 1.00 7.79 N ANISOU 842 NH2 ARG A 295 1085 902 969 95 58 -43 N ATOM 843 N LEU A 296 -1.678 3.995 -4.876 1.00 4.93 N ANISOU 843 N LEU A 296 629 586 658 -37 57 -66 N ATOM 844 CA LEU A 296 -0.611 4.825 -5.439 1.00 5.11 C ANISOU 844 CA LEU A 296 629 661 648 -43 42 -37 C ATOM 845 C LEU A 296 0.259 5.474 -4.383 1.00 5.89 C ANISOU 845 C LEU A 296 745 788 705 -61 20 4 C ATOM 846 O LEU A 296 1.192 6.202 -4.705 1.00 7.06 O ANISOU 846 O LEU A 296 808 981 890 -146 132 -14 O ATOM 847 CB LEU A 296 -1.155 5.912 -6.365 1.00 6.10 C ANISOU 847 CB LEU A 296 828 747 743 -52 -12 -26 C ATOM 848 CG LEU A 296 -2.001 5.424 -7.539 1.00 6.72 C ANISOU 848 CG LEU A 296 819 881 853 -36 -55 69 C ATOM 849 CD1 LEU A 296 -2.507 6.631 -8.364 1.00 8.04 C ANISOU 849 CD1 LEU A 296 963 1098 994 64 -182 130 C ATOM 850 CD2 LEU A 296 -1.216 4.484 -8.439 1.00 7.96 C ANISOU 850 CD2 LEU A 296 1015 1055 952 0 34 89 C ATOM 851 N ILE A 297 -0.031 5.215 -3.118 1.00 4.91 N ANISOU 851 N ILE A 297 565 721 579 -9 84 13 N ATOM 852 CA ILE A 297 0.744 5.811 -2.044 1.00 4.57 C ANISOU 852 CA ILE A 297 583 583 567 -2 29 33 C ATOM 853 C ILE A 297 2.061 5.064 -1.858 1.00 4.10 C ANISOU 853 C ILE A 297 531 508 517 -41 78 0 C ATOM 854 O ILE A 297 2.095 3.826 -1.837 1.00 4.58 O ANISOU 854 O ILE A 297 634 515 591 31 34 21 O ATOM 855 CB ILE A 297 -0.082 5.858 -0.743 1.00 4.98 C ANISOU 855 CB ILE A 297 565 681 644 -17 77 7 C ATOM 856 CG1 ILE A 297 -1.280 6.800 -0.953 1.00 6.19 C ANISOU 856 CG1 ILE A 297 696 850 803 30 17 32 C ATOM 857 CG2 ILE A 297 0.759 6.292 0.421 1.00 5.57 C ANISOU 857 CG2 ILE A 297 768 709 639 41 113 30 C ATOM 858 CD1 ILE A 297 -2.325 6.740 0.164 1.00 6.76 C ANISOU 858 CD1 ILE A 297 801 901 867 26 37 -115 C ATOM 859 N ASN A 298 3.135 5.841 -1.760 1.00 4.18 N ANISOU 859 N ASN A 298 528 498 562 -31 -63 9 N ATOM 860 CA ASN A 298 4.481 5.321 -1.655 1.00 4.06 C ANISOU 860 CA ASN A 298 548 480 513 -19 21 4 C ATOM 861 C ASN A 298 4.905 4.973 -0.226 1.00 3.79 C ANISOU 861 C ASN A 298 484 479 477 -6 37 7 C ATOM 862 O ASN A 298 4.194 5.232 0.730 1.00 3.75 O ANISOU 862 O ASN A 298 553 413 458 16 16 29 O ATOM 863 CB ASN A 298 5.436 6.288 -2.323 1.00 4.20 C ANISOU 863 CB ASN A 298 565 551 477 -19 -2 12 C ATOM 864 CG ASN A 298 5.229 6.327 -3.821 1.00 4.99 C ANISOU 864 CG ASN A 298 676 689 531 -46 106 -17 C ATOM 865 OD1 ASN A 298 5.127 5.279 -4.466 1.00 6.42 O ANISOU 865 OD1 ASN A 298 920 770 747 -11 24 2 O ATOM 866 ND2 ASN A 298 5.198 7.541 -4.393 1.00 7.54 N ANISOU 866 ND2 ASN A 298 1201 823 841 216 66 62 N ATOM 867 N HIS A 299 6.078 4.353 -0.128 1.00 4.15 N ANISOU 867 N HIS A 299 515 543 517 41 -39 27 N ATOM 868 CA HIS A 299 6.627 3.814 1.108 1.00 3.65 C ANISOU 868 CA HIS A 299 467 466 454 0 10 -14 C ATOM 869 C HIS A 299 7.610 4.731 1.807 1.00 3.68 C ANISOU 869 C HIS A 299 466 419 511 -63 -12 8 C ATOM 870 O HIS A 299 8.409 5.404 1.166 1.00 4.39 O ANISOU 870 O HIS A 299 574 591 499 -49 94 47 O ATOM 871 CB HIS A 299 7.410 2.530 0.772 1.00 3.75 C ANISOU 871 CB HIS A 299 488 455 481 1 2 -18 C ATOM 872 CG HIS A 299 8.300 2.054 1.868 1.00 3.89 C ANISOU 872 CG HIS A 299 531 441 504 -52 21 -46 C ATOM 873 ND1 HIS A 299 7.844 1.285 2.918 1.00 4.91 N ANISOU 873 ND1 HIS A 299 742 606 516 78 -4 69 N ATOM 874 CD2 HIS A 299 9.621 2.254 2.092 1.00 5.45 C ANISOU 874 CD2 HIS A 299 622 787 662 14 -19 -5 C ATOM 875 CE1 HIS A 299 8.856 1.017 3.729 1.00 5.37 C ANISOU 875 CE1 HIS A 299 728 672 640 24 -18 -100 C ATOM 876 NE2 HIS A 299 9.941 1.601 3.260 1.00 5.93 N ANISOU 876 NE2 HIS A 299 883 715 653 7 54 6 N ATOM 877 N SER A 300 7.569 4.698 3.135 1.00 4.42 N ANISOU 877 N SER A 300 580 556 543 -37 5 -4 N ATOM 878 CA SER A 300 8.610 5.286 3.992 1.00 5.51 C ANISOU 878 CA SER A 300 678 731 682 -16 -23 18 C ATOM 879 C SER A 300 8.500 4.681 5.371 1.00 6.28 C ANISOU 879 C SER A 300 786 852 748 -48 51 -6 C ATOM 880 O SER A 300 7.409 4.309 5.797 1.00 7.09 O ANISOU 880 O SER A 300 878 1015 799 -32 54 10 O ATOM 881 CB SER A 300 8.406 6.774 4.174 1.00 6.60 C ANISOU 881 CB SER A 300 897 803 807 30 9 32 C ATOM 882 OG SER A 300 9.358 7.329 5.067 1.00 8.45 O ANISOU 882 OG SER A 300 1124 935 1151 -99 -30 -6 O ATOM 883 N LYS A 301 9.627 4.618 6.063 1.00 8.11 N ANISOU 883 N LYS A 301 1044 1124 914 66 30 58 N ATOM 884 CA LYS A 301 9.649 4.225 7.464 1.00 9.11 C ANISOU 884 CA LYS A 301 1209 1218 1031 4 2 49 C ATOM 885 C LYS A 301 9.446 5.432 8.381 1.00 10.13 C ANISOU 885 C LYS A 301 1365 1300 1181 12 8 25 C ATOM 886 O LYS A 301 9.346 5.262 9.600 1.00 11.92 O ANISOU 886 O LYS A 301 1754 1510 1262 57 174 46 O ATOM 887 CB LYS A 301 10.944 3.505 7.799 1.00 9.52 C ANISOU 887 CB LYS A 301 1246 1261 1107 2 -32 29 C ATOM 888 CG LYS A 301 11.039 2.127 7.205 1.00 11.61 C ANISOU 888 CG LYS A 301 1630 1487 1295 -5 -7 -8 C ATOM 889 CD LYS A 301 12.298 1.476 7.671 1.00 14.29 C ANISOU 889 CD LYS A 301 1777 1840 1813 41 44 30 C ATOM 890 CE LYS A 301 12.416 0.072 7.209 1.00 16.02 C ANISOU 890 CE LYS A 301 2097 1993 1997 -4 14 -13 C ATOM 891 NZ LYS A 301 13.723 -0.473 7.708 1.00 17.16 N ANISOU 891 NZ LYS A 301 2166 2161 2192 41 -35 54 N ATOM 892 N CYS A 302 9.428 6.647 7.835 1.00 10.38 N ANISOU 892 N CYS A 302 1393 1344 1204 40 11 54 N ATOM 893 CA CYS A 302 9.103 7.839 8.634 1.00 11.33 C ANISOU 893 CA CYS A 302 1440 1431 1432 60 -13 14 C ATOM 894 C CYS A 302 7.936 8.551 7.965 1.00 11.02 C ANISOU 894 C CYS A 302 1401 1357 1428 45 19 37 C ATOM 895 O CYS A 302 7.948 9.778 7.781 1.00 12.26 O ANISOU 895 O CYS A 302 1510 1450 1695 47 19 72 O ATOM 896 CB CYS A 302 10.308 8.764 8.863 1.00 12.35 C ANISOU 896 CB CYS A 302 1536 1521 1633 90 -21 -3 C ATOM 897 SG CYS A 302 11.207 9.197 7.392 1.00 16.52 S ANISOU 897 SG CYS A 302 2224 1903 2147 109 117 -48 S ATOM 898 N GLY A 303 6.939 7.751 7.625 1.00 9.82 N ANISOU 898 N GLY A 303 1324 1241 1166 96 8 53 N ATOM 899 CA GLY A 303 5.736 8.200 6.957 1.00 9.02 C ANISOU 899 CA GLY A 303 1068 1205 1151 -10 17 -28 C ATOM 900 C GLY A 303 4.799 8.971 7.853 1.00 8.54 C ANISOU 900 C GLY A 303 1077 1137 1029 50 -33 -28 C ATOM 901 O GLY A 303 5.126 9.317 9.003 1.00 9.96 O ANISOU 901 O GLY A 303 1157 1456 1168 144 -78 -107 O ATOM 902 N ASN A 304 3.646 9.294 7.293 1.00 7.02 N ANISOU 902 N ASN A 304 875 975 815 -6 11 -9 N ATOM 903 CA ASN A 304 2.653 10.094 7.967 1.00 6.27 C ANISOU 903 CA ASN A 304 812 847 722 -30 -11 -45 C ATOM 904 C ASN A 304 1.306 9.381 8.054 1.00 6.62 C ANISOU 904 C ASN A 304 796 840 878 -12 89 -24 C ATOM 905 O ASN A 304 0.368 9.915 8.635 1.00 7.61 O ANISOU 905 O ASN A 304 858 978 1054 -28 162 -42 O ATOM 906 CB ASN A 304 2.503 11.462 7.314 1.00 6.26 C ANISOU 906 CB ASN A 304 774 878 725 -46 36 -49 C ATOM 907 CG ASN A 304 2.416 11.397 5.796 1.00 5.96 C ANISOU 907 CG ASN A 304 785 830 650 -84 -54 -6 C ATOM 908 OD1 ASN A 304 1.902 10.438 5.234 1.00 5.55 O ANISOU 908 OD1 ASN A 304 813 693 601 -40 130 -57 O ATOM 909 ND2 ASN A 304 2.826 12.473 5.138 1.00 7.33 N ANISOU 909 ND2 ASN A 304 931 967 886 -145 -60 -8 N ATOM 910 N CYS A 305 1.247 8.157 7.532 1.00 7.09 N ANISOU 910 N CYS A 305 799 892 1002 -1 92 -33 N ATOM 911 CA CYS A 305 0.051 7.317 7.617 1.00 6.97 C ANISOU 911 CA CYS A 305 825 829 992 5 82 -27 C ATOM 912 C CYS A 305 0.407 5.962 8.215 1.00 7.27 C ANISOU 912 C CYS A 305 841 906 1014 21 24 -8 C ATOM 913 O CYS A 305 1.552 5.524 8.111 1.00 6.75 O ANISOU 913 O CYS A 305 777 757 1029 -17 51 -7 O ATOM 914 CB CYS A 305 -0.561 7.101 6.238 1.00 7.77 C ANISOU 914 CB CYS A 305 784 986 1180 -33 2 -22 C ATOM 915 SG CYS A 305 -1.173 8.606 5.465 1.00 10.30 S ANISOU 915 SG CYS A 305 1094 1301 1518 40 -18 139 S ATOM 916 N GLN A 306 -0.591 5.318 8.823 1.00 7.62 N ANISOU 916 N GLN A 306 901 884 1110 -60 2 -44 N ATOM 917 CA GLN A 306 -0.469 3.986 9.409 1.00 8.67 C ANISOU 917 CA GLN A 306 1038 1050 1205 -33 -55 0 C ATOM 918 C GLN A 306 -1.634 3.120 8.925 1.00 8.30 C ANISOU 918 C GLN A 306 941 983 1229 -20 25 -35 C ATOM 919 O GLN A 306 -2.772 3.576 8.866 1.00 7.82 O ANISOU 919 O GLN A 306 853 955 1162 16 -60 -55 O ATOM 920 CB GLN A 306 -0.427 4.043 10.934 1.00 10.40 C ANISOU 920 CB GLN A 306 1344 1242 1363 -9 -45 -55 C ATOM 921 CG GLN A 306 0.818 4.771 11.419 1.00 15.17 C ANISOU 921 CG GLN A 306 1716 1856 2192 -84 -53 -4 C ATOM 922 CD GLN A 306 0.897 4.934 12.927 1.00 21.37 C ANISOU 922 CD GLN A 306 2806 2773 2539 -52 -16 -19 C ATOM 923 OE1 GLN A 306 -0.029 5.472 13.562 1.00 25.87 O ANISOU 923 OE1 GLN A 306 3241 3145 3441 81 215 2 O ATOM 924 NE2 GLN A 306 2.016 4.497 13.512 1.00 24.62 N ANISOU 924 NE2 GLN A 306 3028 3099 3226 95 -72 35 N ATOM 925 N THR A 307 -1.319 1.908 8.480 1.00 7.78 N ANISOU 925 N THR A 307 897 895 1163 -48 10 -29 N ATOM 926 CA THR A 307 -2.354 0.987 8.026 1.00 7.20 C ANISOU 926 CA THR A 307 844 876 1016 -20 37 4 C ATOM 927 C THR A 307 -3.020 0.305 9.207 1.00 6.39 C ANISOU 927 C THR A 307 768 809 851 9 -12 0 C ATOM 928 O THR A 307 -2.364 -0.140 10.130 1.00 6.91 O ANISOU 928 O THR A 307 832 877 914 -60 33 -32 O ATOM 929 CB THR A 307 -1.773 -0.073 7.091 1.00 7.50 C ANISOU 929 CB THR A 307 996 869 983 -28 48 7 C ATOM 930 OG1 THR A 307 -1.024 0.553 6.051 1.00 9.28 O ANISOU 930 OG1 THR A 307 1228 1086 1211 -105 250 -57 O ATOM 931 CG2 THR A 307 -2.855 -0.824 6.376 1.00 9.03 C ANISOU 931 CG2 THR A 307 1166 1096 1167 -32 50 -39 C ATOM 932 N LYS A 308 -4.351 0.229 9.137 1.00 5.97 N ANISOU 932 N LYS A 308 687 739 842 -38 -17 -4 N ATOM 933 CA LYS A 308 -5.148 -0.413 10.152 1.00 6.61 C ANISOU 933 CA LYS A 308 804 842 865 -11 -51 3 C ATOM 934 C LYS A 308 -6.142 -1.367 9.484 1.00 6.08 C ANISOU 934 C LYS A 308 787 755 766 -76 -18 -5 C ATOM 935 O LYS A 308 -6.562 -1.147 8.349 1.00 5.87 O ANISOU 935 O LYS A 308 743 587 900 -70 -82 8 O ATOM 936 CB LYS A 308 -5.915 0.621 10.968 1.00 7.79 C ANISOU 936 CB LYS A 308 1035 925 999 -33 65 2 C ATOM 937 CG LYS A 308 -5.025 1.689 11.604 1.00 10.81 C ANISOU 937 CG LYS A 308 1387 1305 1414 -56 18 -81 C ATOM 938 CD LYS A 308 -4.189 1.148 12.732 1.00 14.55 C ANISOU 938 CD LYS A 308 1757 1914 1856 29 -113 -33 C ATOM 939 CE LYS A 308 -3.348 2.251 13.363 1.00 17.56 C ANISOU 939 CE LYS A 308 2270 2088 2313 -69 -35 -70 C ATOM 940 NZ LYS A 308 -2.750 1.810 14.653 1.00 19.29 N ANISOU 940 NZ LYS A 308 2529 2408 2391 31 -25 22 N ATOM 941 N LEU A 309 -6.488 -2.426 10.199 1.00 6.91 N ANISOU 941 N LEU A 309 949 851 823 -29 -70 -7 N ATOM 942 CA LEU A 309 -7.530 -3.343 9.765 1.00 7.67 C ANISOU 942 CA LEU A 309 965 962 987 -22 -2 -24 C ATOM 943 C LEU A 309 -8.860 -2.864 10.345 1.00 7.32 C ANISOU 943 C LEU A 309 940 928 912 -2 -3 6 C ATOM 944 O LEU A 309 -8.967 -2.633 11.559 1.00 8.14 O ANISOU 944 O LEU A 309 974 1095 1024 -16 28 -109 O ATOM 945 CB LEU A 309 -7.222 -4.743 10.276 1.00 8.59 C ANISOU 945 CB LEU A 309 1090 1071 1100 15 -25 -6 C ATOM 946 CG LEU A 309 -8.328 -5.772 10.153 1.00 12.36 C ANISOU 946 CG LEU A 309 1597 1446 1654 -73 -23 -8 C ATOM 947 CD1 LEU A 309 -8.516 -6.086 8.709 1.00 14.49 C ANISOU 947 CD1 LEU A 309 1953 1798 1753 -46 43 -4 C ATOM 948 CD2 LEU A 309 -7.981 -7.018 10.978 1.00 14.45 C ANISOU 948 CD2 LEU A 309 1895 1701 1894 45 -2 41 C ATOM 949 N HIS A 310 -9.854 -2.702 9.482 1.00 7.28 N ANISOU 949 N HIS A 310 966 894 906 -75 -15 -56 N ATOM 950 CA HIS A 310 -11.185 -2.318 9.889 1.00 7.75 C ANISOU 950 CA HIS A 310 1066 954 922 -22 -1 -32 C ATOM 951 C HIS A 310 -12.195 -3.263 9.259 1.00 7.89 C ANISOU 951 C HIS A 310 995 994 1006 -19 -2 -16 C ATOM 952 O HIS A 310 -12.309 -3.313 8.039 1.00 8.87 O ANISOU 952 O HIS A 310 1183 1054 1131 -52 -36 -139 O ATOM 953 CB HIS A 310 -11.502 -0.902 9.441 1.00 7.92 C ANISOU 953 CB HIS A 310 1063 958 987 -75 -53 4 C ATOM 954 CG HIS A 310 -12.763 -0.369 10.018 1.00 9.56 C ANISOU 954 CG HIS A 310 1302 1164 1166 28 -41 42 C ATOM 955 ND1 HIS A 310 -12.811 0.256 11.245 1.00 11.41 N ANISOU 955 ND1 HIS A 310 1566 1382 1385 66 16 -100 N ATOM 956 CD2 HIS A 310 -14.037 -0.405 9.562 1.00 9.57 C ANISOU 956 CD2 HIS A 310 1236 1218 1181 -115 -1 42 C ATOM 957 CE1 HIS A 310 -14.057 0.607 11.506 1.00 12.12 C ANISOU 957 CE1 HIS A 310 1563 1486 1554 -8 -10 11 C ATOM 958 NE2 HIS A 310 -14.819 0.222 10.500 1.00 11.56 N ANISOU 958 NE2 HIS A 310 1543 1341 1509 34 -2 2 N ATOM 959 N ASP A 311 -12.941 -3.988 10.073 1.00 8.86 N ANISOU 959 N ASP A 311 1187 1025 1151 11 -1 -8 N ATOM 960 CA ASP A 311 -13.917 -4.922 9.528 1.00 9.18 C ANISOU 960 CA ASP A 311 1128 1161 1198 -1 -26 6 C ATOM 961 C ASP A 311 -15.312 -4.326 9.513 1.00 8.75 C ANISOU 961 C ASP A 311 1107 1069 1148 15 29 5 C ATOM 962 O ASP A 311 -15.698 -3.614 10.424 1.00 9.39 O ANISOU 962 O ASP A 311 1168 1100 1298 24 -10 1 O ATOM 963 CB ASP A 311 -13.919 -6.234 10.300 1.00 10.26 C ANISOU 963 CB ASP A 311 1277 1211 1408 8 -33 0 C ATOM 964 CG ASP A 311 -14.308 -6.062 11.734 1.00 13.36 C ANISOU 964 CG ASP A 311 1706 1756 1614 37 13 -18 C ATOM 965 OD1 ASP A 311 -13.805 -5.121 12.366 1.00 15.96 O ANISOU 965 OD1 ASP A 311 2012 1996 2054 -62 -87 -45 O ATOM 966 OD2 ASP A 311 -15.123 -6.808 12.326 1.00 18.70 O ANISOU 966 OD2 ASP A 311 2421 2264 2419 -146 40 62 O ATOM 967 N ILE A 312 -16.043 -4.611 8.450 1.00 8.42 N ANISOU 967 N ILE A 312 1047 1030 1120 0 41 3 N ATOM 968 CA ILE A 312 -17.430 -4.200 8.329 1.00 8.73 C ANISOU 968 CA ILE A 312 1087 1110 1120 14 -11 -14 C ATOM 969 C ILE A 312 -18.216 -5.490 8.127 1.00 8.49 C ANISOU 969 C ILE A 312 1052 1073 1100 -6 5 13 C ATOM 970 O ILE A 312 -18.073 -6.138 7.100 1.00 7.63 O ANISOU 970 O ILE A 312 856 998 1041 -48 4 24 O ATOM 971 CB ILE A 312 -17.666 -3.260 7.135 1.00 9.06 C ANISOU 971 CB ILE A 312 1131 1136 1174 1 10 -12 C ATOM 972 CG1 ILE A 312 -16.800 -2.005 7.248 1.00 9.78 C ANISOU 972 CG1 ILE A 312 1289 1208 1216 27 -4 -17 C ATOM 973 CG2 ILE A 312 -19.181 -2.933 7.044 1.00 9.96 C ANISOU 973 CG2 ILE A 312 1265 1202 1315 37 -7 15 C ATOM 974 CD1 ILE A 312 -16.962 -1.045 6.076 1.00 10.77 C ANISOU 974 CD1 ILE A 312 1408 1314 1369 28 25 55 C ATOM 975 N ASP A 313 -19.017 -5.876 9.114 1.00 9.58 N ANISOU 975 N ASP A 313 1169 1240 1228 20 -18 -19 N ATOM 976 CA ASP A 313 -19.820 -7.087 9.037 1.00 10.02 C ANISOU 976 CA ASP A 313 1279 1251 1275 21 10 16 C ATOM 977 C ASP A 313 -19.119 -8.304 8.411 1.00 9.51 C ANISOU 977 C ASP A 313 1209 1204 1200 -1 2 11 C ATOM 978 O ASP A 313 -19.658 -8.956 7.508 1.00 9.07 O ANISOU 978 O ASP A 313 1134 1165 1147 2 -3 44 O ATOM 979 CB ASP A 313 -21.115 -6.763 8.308 1.00 10.48 C ANISOU 979 CB ASP A 313 1289 1329 1361 -33 -6 45 C ATOM 980 CG ASP A 313 -21.942 -5.737 9.057 1.00 13.66 C ANISOU 980 CG ASP A 313 1782 1673 1732 61 88 -38 C ATOM 981 OD1 ASP A 313 -22.194 -5.966 10.261 1.00 17.85 O ANISOU 981 OD1 ASP A 313 2489 2261 2030 93 52 68 O ATOM 982 OD2 ASP A 313 -22.366 -4.668 8.553 1.00 16.07 O ANISOU 982 OD2 ASP A 313 2229 1940 1935 125 39 52 O ATOM 983 N GLY A 314 -17.929 -8.609 8.928 1.00 8.95 N ANISOU 983 N GLY A 314 1139 1121 1138 0 18 24 N ATOM 984 CA GLY A 314 -17.197 -9.806 8.549 1.00 9.22 C ANISOU 984 CA GLY A 314 1160 1156 1186 5 12 12 C ATOM 985 C GLY A 314 -16.255 -9.673 7.379 1.00 9.26 C ANISOU 985 C GLY A 314 1184 1121 1210 41 49 23 C ATOM 986 O GLY A 314 -15.560 -10.628 7.031 1.00 10.29 O ANISOU 986 O GLY A 314 1266 1243 1398 89 118 66 O ATOM 987 N VAL A 315 -16.239 -8.503 6.757 1.00 8.40 N ANISOU 987 N VAL A 315 1042 1013 1136 -7 51 13 N ATOM 988 CA VAL A 315 -15.362 -8.261 5.628 1.00 8.13 C ANISOU 988 CA VAL A 315 1022 993 1073 -1 28 -23 C ATOM 989 C VAL A 315 -14.274 -7.291 6.079 1.00 7.26 C ANISOU 989 C VAL A 315 831 891 1033 24 22 -20 C ATOM 990 O VAL A 315 -14.554 -6.170 6.508 1.00 6.94 O ANISOU 990 O VAL A 315 735 898 1002 0 56 -31 O ATOM 991 CB VAL A 315 -16.123 -7.663 4.430 1.00 8.48 C ANISOU 991 CB VAL A 315 1040 1039 1142 20 22 -3 C ATOM 992 CG1 VAL A 315 -15.179 -7.422 3.260 1.00 9.52 C ANISOU 992 CG1 VAL A 315 1246 1226 1144 58 54 6 C ATOM 993 CG2 VAL A 315 -17.283 -8.551 4.017 1.00 9.05 C ANISOU 993 CG2 VAL A 315 1103 1161 1172 49 -2 -58 C ATOM 994 N PRO A 316 -13.022 -7.725 6.023 1.00 7.13 N ANISOU 994 N PRO A 316 882 850 975 19 20 -16 N ATOM 995 CA PRO A 316 -11.924 -6.860 6.402 1.00 6.67 C ANISOU 995 CA PRO A 316 851 820 862 23 -4 -16 C ATOM 996 C PRO A 316 -11.591 -5.841 5.328 1.00 6.54 C ANISOU 996 C PRO A 316 896 789 797 10 -25 -10 C ATOM 997 O PRO A 316 -11.676 -6.109 4.136 1.00 7.87 O ANISOU 997 O PRO A 316 1189 850 949 -88 52 -42 O ATOM 998 CB PRO A 316 -10.779 -7.858 6.566 1.00 6.71 C ANISOU 998 CB PRO A 316 812 872 865 28 -32 -22 C ATOM 999 CG PRO A 316 -11.061 -8.829 5.484 1.00 6.95 C ANISOU 999 CG PRO A 316 854 866 919 80 5 -14 C ATOM 1000 CD PRO A 316 -12.538 -9.064 5.636 1.00 6.91 C ANISOU 1000 CD PRO A 316 853 811 959 19 10 -37 C ATOM 1001 N HIS A 317 -11.215 -4.656 5.774 1.00 6.39 N ANISOU 1001 N HIS A 317 874 777 775 -84 -5 12 N ATOM 1002 CA HIS A 317 -10.750 -3.591 4.902 1.00 5.87 C ANISOU 1002 CA HIS A 317 783 742 706 -29 -25 11 C ATOM 1003 C HIS A 317 -9.447 -3.059 5.480 1.00 5.84 C ANISOU 1003 C HIS A 317 757 740 721 -7 -34 3 C ATOM 1004 O HIS A 317 -9.299 -2.973 6.700 1.00 7.52 O ANISOU 1004 O HIS A 317 1007 1014 834 -56 -27 15 O ATOM 1005 CB HIS A 317 -11.756 -2.459 4.882 1.00 5.68 C ANISOU 1005 CB HIS A 317 773 717 666 -29 -7 -5 C ATOM 1006 CG HIS A 317 -13.069 -2.852 4.295 1.00 6.44 C ANISOU 1006 CG HIS A 317 815 793 839 57 -77 -32 C ATOM 1007 ND1 HIS A 317 -13.343 -2.721 2.954 1.00 8.00 N ANISOU 1007 ND1 HIS A 317 1034 1148 857 -39 -74 -11 N ATOM 1008 CD2 HIS A 317 -14.168 -3.406 4.856 1.00 7.67 C ANISOU 1008 CD2 HIS A 317 1049 904 959 25 38 -46 C ATOM 1009 CE1 HIS A 317 -14.566 -3.166 2.716 1.00 7.35 C ANISOU 1009 CE1 HIS A 317 953 962 877 -38 23 0 C ATOM 1010 NE2 HIS A 317 -15.091 -3.582 3.854 1.00 8.66 N ANISOU 1010 NE2 HIS A 317 1183 1104 1001 13 28 21 N ATOM 1011 N LEU A 318 -8.517 -2.697 4.611 1.00 5.33 N ANISOU 1011 N LEU A 318 724 631 670 -13 -18 -5 N ATOM 1012 CA LEU A 318 -7.274 -2.064 5.045 1.00 5.13 C ANISOU 1012 CA LEU A 318 658 672 618 -4 -9 0 C ATOM 1013 C LEU A 318 -7.436 -0.575 4.800 1.00 5.50 C ANISOU 1013 C LEU A 318 714 708 665 51 -18 -32 C ATOM 1014 O LEU A 318 -7.766 -0.162 3.683 1.00 6.76 O ANISOU 1014 O LEU A 318 1067 683 817 93 14 10 O ATOM 1015 CB LEU A 318 -6.069 -2.571 4.244 1.00 5.95 C ANISOU 1015 CB LEU A 318 694 800 764 -21 -14 -29 C ATOM 1016 CG LEU A 318 -5.604 -3.999 4.510 1.00 7.66 C ANISOU 1016 CG LEU A 318 965 913 1032 -5 29 -52 C ATOM 1017 CD1 LEU A 318 -4.375 -4.295 3.658 1.00 9.03 C ANISOU 1017 CD1 LEU A 318 1112 1015 1301 62 119 30 C ATOM 1018 CD2 LEU A 318 -5.348 -4.245 5.985 1.00 9.55 C ANISOU 1018 CD2 LEU A 318 1331 1072 1224 111 1 -20 C ATOM 1019 N ILE A 319 -7.225 0.224 5.843 1.00 5.57 N ANISOU 1019 N ILE A 319 698 656 760 2 -48 12 N ATOM 1020 CA ILE A 319 -7.343 1.658 5.716 1.00 5.53 C ANISOU 1020 CA ILE A 319 652 674 772 -19 -39 -8 C ATOM 1021 C ILE A 319 -6.092 2.334 6.210 1.00 5.79 C ANISOU 1021 C ILE A 319 692 744 761 -15 -19 27 C ATOM 1022 O ILE A 319 -5.371 1.801 7.037 1.00 6.74 O ANISOU 1022 O ILE A 319 802 769 987 -22 -86 156 O ATOM 1023 CB ILE A 319 -8.546 2.156 6.508 1.00 6.13 C ANISOU 1023 CB ILE A 319 747 717 865 -15 -1 10 C ATOM 1024 CG1 ILE A 319 -8.363 1.928 8.001 1.00 7.26 C ANISOU 1024 CG1 ILE A 319 812 1002 943 4 -3 -25 C ATOM 1025 CG2 ILE A 319 -9.815 1.521 5.980 1.00 6.93 C ANISOU 1025 CG2 ILE A 319 804 804 1025 -45 -25 3 C ATOM 1026 CD1 ILE A 319 -9.480 2.543 8.837 1.00 9.16 C ANISOU 1026 CD1 ILE A 319 1150 1149 1178 48 57 -70 C ATOM 1027 N LEU A 320 -5.851 3.515 5.681 1.00 6.11 N ANISOU 1027 N LEU A 320 656 710 952 8 -29 22 N ATOM 1028 CA LEU A 320 -4.760 4.348 6.144 1.00 6.59 C ANISOU 1028 CA LEU A 320 769 822 910 -42 25 -19 C ATOM 1029 C LEU A 320 -5.324 5.469 6.966 1.00 6.84 C ANISOU 1029 C LEU A 320 762 804 1033 -30 5 -1 C ATOM 1030 O LEU A 320 -6.278 6.147 6.533 1.00 7.31 O ANISOU 1030 O LEU A 320 873 807 1097 26 -76 -111 O ATOM 1031 CB LEU A 320 -4.029 4.957 4.945 1.00 6.95 C ANISOU 1031 CB LEU A 320 729 884 1028 -59 104 59 C ATOM 1032 CG LEU A 320 -3.165 4.005 4.134 1.00 9.91 C ANISOU 1032 CG LEU A 320 1255 1244 1267 21 138 -62 C ATOM 1033 CD1 LEU A 320 -2.527 4.795 2.979 1.00 12.89 C ANISOU 1033 CD1 LEU A 320 1655 1660 1581 1 119 131 C ATOM 1034 CD2 LEU A 320 -2.080 3.434 4.962 1.00 10.93 C ANISOU 1034 CD2 LEU A 320 1375 1346 1431 53 128 -7 C ATOM 1035 N ILE A 321 -4.736 5.657 8.131 1.00 7.11 N ANISOU 1035 N ILE A 321 770 875 1055 3 46 -29 N ATOM 1036 CA ILE A 321 -5.091 6.743 9.037 1.00 7.59 C ANISOU 1036 CA ILE A 321 890 933 1060 -43 -9 -55 C ATOM 1037 C ILE A 321 -3.852 7.617 9.223 1.00 6.65 C ANISOU 1037 C ILE A 321 780 728 1018 -22 50 7 C ATOM 1038 O ILE A 321 -2.744 7.113 9.230 1.00 7.28 O ANISOU 1038 O ILE A 321 788 721 1256 -56 32 47 O ATOM 1039 CB ILE A 321 -5.510 6.198 10.418 1.00 9.24 C ANISOU 1039 CB ILE A 321 1095 1161 1253 -87 77 -13 C ATOM 1040 CG1 ILE A 321 -6.691 5.208 10.317 1.00 11.53 C ANISOU 1040 CG1 ILE A 321 1392 1400 1588 -163 106 -36 C ATOM 1041 CG2 ILE A 321 -5.835 7.336 11.333 1.00 11.91 C ANISOU 1041 CG2 ILE A 321 1537 1362 1625 -35 33 -1 C ATOM 1042 CD1 ILE A 321 -7.571 5.436 9.241 1.00 14.58 C ANISOU 1042 CD1 ILE A 321 1838 1758 1944 -29 -49 54 C ATOM 1043 N ALA A 322 -4.045 8.916 9.418 1.00 5.64 N ANISOU 1043 N ALA A 322 703 659 781 -49 43 -51 N ATOM 1044 CA ALA A 322 -2.930 9.822 9.674 1.00 5.01 C ANISOU 1044 CA ALA A 322 612 640 651 -13 61 -29 C ATOM 1045 C ALA A 322 -2.284 9.517 11.011 1.00 5.37 C ANISOU 1045 C ALA A 322 648 664 729 -7 37 -32 C ATOM 1046 O ALA A 322 -2.982 9.436 12.037 1.00 6.53 O ANISOU 1046 O ALA A 322 740 887 854 3 43 110 O ATOM 1047 CB ALA A 322 -3.441 11.239 9.669 1.00 4.76 C ANISOU 1047 CB ALA A 322 554 595 659 -3 -32 48 C ATOM 1048 N SER A 323 -0.949 9.389 11.015 1.00 6.32 N ANISOU 1048 N SER A 323 750 836 814 8 0 -32 N ATOM 1049 CA SER A 323 -0.203 9.091 12.214 1.00 7.19 C ANISOU 1049 CA SER A 323 903 913 915 13 0 41 C ATOM 1050 C SER A 323 0.301 10.350 12.904 1.00 6.57 C ANISOU 1050 C SER A 323 777 931 786 13 -33 -6 C ATOM 1051 O SER A 323 0.848 10.290 14.015 1.00 7.73 O ANISOU 1051 O SER A 323 1037 1084 816 -8 -76 77 O ATOM 1052 CB SER A 323 0.967 8.164 11.891 1.00 8.16 C ANISOU 1052 CB SER A 323 1040 1032 1025 105 57 18 C ATOM 1053 OG SER A 323 1.939 8.761 11.042 1.00 11.85 O ANISOU 1053 OG SER A 323 1371 1533 1599 59 50 237 O ATOM 1054 N ARG A 324 0.072 11.489 12.264 1.00 6.56 N ANISOU 1054 N ARG A 324 833 901 759 -20 -33 -35 N ATOM 1055 CA ARG A 324 0.483 12.779 12.768 1.00 7.14 C ANISOU 1055 CA ARG A 324 935 922 853 5 -23 -13 C ATOM 1056 C ARG A 324 -0.300 13.816 11.947 1.00 6.84 C ANISOU 1056 C ARG A 324 841 883 875 -7 -34 -56 C ATOM 1057 O ARG A 324 -0.980 13.455 10.984 1.00 6.59 O ANISOU 1057 O ARG A 324 822 784 895 32 -63 -26 O ATOM 1058 CB ARG A 324 2.015 12.856 12.628 1.00 7.93 C ANISOU 1058 CB ARG A 324 963 1095 954 -17 -6 -25 C ATOM 1059 CG ARG A 324 2.732 14.161 12.630 1.00 12.24 C ANISOU 1059 CG ARG A 324 1623 1464 1562 -11 52 -7 C ATOM 1060 CD ARG A 324 3.142 14.654 11.233 1.00 14.87 C ANISOU 1060 CD ARG A 324 1952 1993 1703 -34 31 93 C ATOM 1061 NE ARG A 324 4.060 13.906 10.349 1.00 14.70 N ANISOU 1061 NE ARG A 324 1526 1879 2180 -1 -84 118 N ATOM 1062 CZ ARG A 324 4.173 14.280 9.060 1.00 13.45 C ANISOU 1062 CZ ARG A 324 1594 1689 1826 -121 -52 -129 C ATOM 1063 NH1 ARG A 324 3.445 15.316 8.652 1.00 12.17 N ANISOU 1063 NH1 ARG A 324 1325 1650 1649 -52 -48 -55 N ATOM 1064 NH2 ARG A 324 4.981 13.718 8.173 1.00 17.30 N ANISOU 1064 NH2 ARG A 324 1936 2049 2586 -46 63 -123 N ATOM 1065 N ASP A 325 -0.291 15.072 12.365 1.00 7.72 N ANISOU 1065 N ASP A 325 981 936 1014 20 -33 -8 N ATOM 1066 CA ASP A 325 -0.916 16.108 11.572 1.00 7.76 C ANISOU 1066 CA ASP A 325 982 963 1001 14 -19 -15 C ATOM 1067 C ASP A 325 -0.164 16.202 10.227 1.00 7.41 C ANISOU 1067 C ASP A 325 879 935 1002 5 -10 52 C ATOM 1068 O ASP A 325 1.077 16.291 10.198 1.00 7.91 O ANISOU 1068 O ASP A 325 897 1026 1082 74 9 66 O ATOM 1069 CB ASP A 325 -0.848 17.464 12.300 1.00 7.79 C ANISOU 1069 CB ASP A 325 987 919 1050 -1 -13 -33 C ATOM 1070 CG ASP A 325 -1.748 17.550 13.534 1.00 10.06 C ANISOU 1070 CG ASP A 325 1208 1335 1279 -55 28 0 C ATOM 1071 OD1 ASP A 325 -2.705 16.743 13.709 1.00 10.43 O ANISOU 1071 OD1 ASP A 325 1129 1377 1454 -117 -88 -48 O ATOM 1072 OD2 ASP A 325 -1.553 18.435 14.402 1.00 13.09 O ANISOU 1072 OD2 ASP A 325 1589 1602 1782 0 28 -127 O ATOM 1073 N ILE A 326 -0.916 16.226 9.130 1.00 7.19 N ANISOU 1073 N ILE A 326 891 934 905 4 -4 -6 N ATOM 1074 CA ILE A 326 -0.360 16.320 7.774 1.00 7.28 C ANISOU 1074 CA ILE A 326 859 958 946 41 -9 33 C ATOM 1075 C ILE A 326 -0.784 17.620 7.128 1.00 7.24 C ANISOU 1075 C ILE A 326 863 949 936 9 -15 41 C ATOM 1076 O ILE A 326 -1.973 17.949 7.118 1.00 8.27 O ANISOU 1076 O ILE A 326 852 1107 1184 17 22 122 O ATOM 1077 CB ILE A 326 -0.846 15.171 6.881 1.00 7.87 C ANISOU 1077 CB ILE A 326 928 1004 1057 31 -6 19 C ATOM 1078 CG1 ILE A 326 -0.526 13.827 7.503 1.00 7.67 C ANISOU 1078 CG1 ILE A 326 899 1030 984 -10 18 57 C ATOM 1079 CG2 ILE A 326 -0.239 15.273 5.481 1.00 8.70 C ANISOU 1079 CG2 ILE A 326 1030 1174 1101 61 -31 35 C ATOM 1080 CD1 ILE A 326 -1.118 12.674 6.784 1.00 7.53 C ANISOU 1080 CD1 ILE A 326 959 846 1055 38 19 88 C ATOM 1081 N ALA A 327 0.184 18.351 6.594 1.00 6.84 N ANISOU 1081 N ALA A 327 811 954 831 -1 -21 29 N ATOM 1082 CA ALA A 327 -0.065 19.606 5.897 1.00 6.53 C ANISOU 1082 CA ALA A 327 813 823 844 11 -12 -16 C ATOM 1083 C ALA A 327 -0.344 19.438 4.407 1.00 6.75 C ANISOU 1083 C ALA A 327 870 837 855 19 -1 -11 C ATOM 1084 O ALA A 327 0.165 18.543 3.760 1.00 6.12 O ANISOU 1084 O ALA A 327 713 778 832 115 -38 -30 O ATOM 1085 CB ALA A 327 1.127 20.522 6.050 1.00 6.45 C ANISOU 1085 CB ALA A 327 820 867 763 -25 -39 -18 C ATOM 1086 N ALA A 328 -1.137 20.348 3.864 1.00 7.23 N ANISOU 1086 N ALA A 328 895 953 898 58 -26 47 N ATOM 1087 CA ALA A 328 -1.378 20.377 2.438 1.00 7.57 C ANISOU 1087 CA ALA A 328 983 933 958 28 -16 -14 C ATOM 1088 C ALA A 328 -0.035 20.468 1.744 1.00 7.59 C ANISOU 1088 C ALA A 328 957 950 977 19 -43 31 C ATOM 1089 O ALA A 328 0.868 21.217 2.170 1.00 8.64 O ANISOU 1089 O ALA A 328 1140 959 1182 11 -45 -14 O ATOM 1090 CB ALA A 328 -2.233 21.557 2.075 1.00 7.95 C ANISOU 1090 CB ALA A 328 1007 1038 973 65 -8 49 C ATOM 1091 N GLY A 329 0.110 19.684 0.687 1.00 7.50 N ANISOU 1091 N GLY A 329 965 913 969 12 -56 -1 N ATOM 1092 CA GLY A 329 1.341 19.651 -0.074 1.00 7.73 C ANISOU 1092 CA GLY A 329 1013 964 958 12 -33 21 C ATOM 1093 C GLY A 329 2.281 18.524 0.288 1.00 7.72 C ANISOU 1093 C GLY A 329 969 990 975 32 -8 17 C ATOM 1094 O GLY A 329 3.237 18.265 -0.437 1.00 9.20 O ANISOU 1094 O GLY A 329 1157 1281 1057 135 17 95 O ATOM 1095 N GLU A 330 2.046 17.861 1.408 1.00 7.18 N ANISOU 1095 N GLU A 330 865 923 941 26 -2 -3 N ATOM 1096 CA GLU A 330 2.913 16.739 1.776 1.00 7.02 C ANISOU 1096 CA GLU A 330 877 879 909 16 -1 -6 C ATOM 1097 C GLU A 330 2.554 15.468 1.030 1.00 6.10 C ANISOU 1097 C GLU A 330 738 821 757 27 -24 -4 C ATOM 1098 O GLU A 330 1.385 15.155 0.852 1.00 5.90 O ANISOU 1098 O GLU A 330 685 763 791 66 20 -43 O ATOM 1099 CB GLU A 330 2.840 16.431 3.269 1.00 7.33 C ANISOU 1099 CB GLU A 330 921 916 948 15 23 35 C ATOM 1100 CG GLU A 330 3.353 17.542 4.161 1.00 8.83 C ANISOU 1100 CG GLU A 330 1139 1093 1122 66 -68 -10 C ATOM 1101 CD GLU A 330 3.752 17.026 5.525 1.00 10.23 C ANISOU 1101 CD GLU A 330 1425 1348 1110 92 -40 -28 C ATOM 1102 OE1 GLU A 330 3.039 17.304 6.522 1.00 9.57 O ANISOU 1102 OE1 GLU A 330 1007 1309 1319 91 -13 93 O ATOM 1103 OE2 GLU A 330 4.798 16.333 5.578 1.00 12.61 O ANISOU 1103 OE2 GLU A 330 1495 1693 1600 135 -62 47 O ATOM 1104 N GLU A 331 3.572 14.706 0.648 1.00 5.95 N ANISOU 1104 N GLU A 331 763 784 712 18 12 -19 N ATOM 1105 CA GLU A 331 3.346 13.392 0.093 1.00 5.56 C ANISOU 1105 CA GLU A 331 697 749 666 7 0 52 C ATOM 1106 C GLU A 331 2.896 12.459 1.218 1.00 4.90 C ANISOU 1106 C GLU A 331 625 643 594 -16 10 -23 C ATOM 1107 O GLU A 331 3.488 12.460 2.301 1.00 5.90 O ANISOU 1107 O GLU A 331 839 755 646 -16 39 51 O ATOM 1108 CB GLU A 331 4.617 12.824 -0.542 1.00 6.63 C ANISOU 1108 CB GLU A 331 832 862 825 63 11 54 C ATOM 1109 CG GLU A 331 4.298 11.560 -1.304 1.00 8.05 C ANISOU 1109 CG GLU A 331 984 1069 1004 66 21 14 C ATOM 1110 CD GLU A 331 5.492 10.840 -1.884 1.00 9.07 C ANISOU 1110 CD GLU A 331 1144 1203 1096 60 58 -41 C ATOM 1111 OE1 GLU A 331 6.638 11.275 -1.640 1.00 10.47 O ANISOU 1111 OE1 GLU A 331 1246 1552 1179 48 54 -99 O ATOM 1112 OE2 GLU A 331 5.224 9.830 -2.577 1.00 8.52 O ANISOU 1112 OE2 GLU A 331 1088 1215 931 35 50 -3 O ATOM 1113 N LEU A 332 1.834 11.699 0.953 1.00 4.25 N ANISOU 1113 N LEU A 332 501 612 501 17 -15 -10 N ATOM 1114 CA LEU A 332 1.391 10.662 1.864 1.00 4.60 C ANISOU 1114 CA LEU A 332 549 570 626 7 2 -15 C ATOM 1115 C LEU A 332 2.314 9.447 1.725 1.00 4.01 C ANISOU 1115 C LEU A 332 552 503 465 11 -1 -31 C ATOM 1116 O LEU A 332 2.639 9.026 0.600 1.00 4.43 O ANISOU 1116 O LEU A 332 585 572 526 7 77 -46 O ATOM 1117 CB LEU A 332 -0.033 10.248 1.533 1.00 4.94 C ANISOU 1117 CB LEU A 332 624 690 563 -1 19 -54 C ATOM 1118 CG LEU A 332 -1.069 11.372 1.637 1.00 6.72 C ANISOU 1118 CG LEU A 332 844 816 891 78 47 89 C ATOM 1119 CD1 LEU A 332 -2.375 10.879 1.134 1.00 8.95 C ANISOU 1119 CD1 LEU A 332 1058 1306 1036 10 27 -6 C ATOM 1120 CD2 LEU A 332 -1.191 11.909 3.047 1.00 7.52 C ANISOU 1120 CD2 LEU A 332 914 867 1076 53 4 5 C ATOM 1121 N LEU A 333 2.677 8.861 2.862 1.00 4.16 N ANISOU 1121 N LEU A 333 556 583 437 3 75 -10 N ATOM 1122 CA LEU A 333 3.634 7.759 2.891 1.00 4.19 C ANISOU 1122 CA LEU A 333 574 509 509 -2 -3 48 C ATOM 1123 C LEU A 333 3.365 6.862 4.079 1.00 4.50 C ANISOU 1123 C LEU A 333 680 506 521 -42 42 -8 C ATOM 1124 O LEU A 333 2.977 7.347 5.131 1.00 4.76 O ANISOU 1124 O LEU A 333 769 508 529 26 140 13 O ATOM 1125 CB LEU A 333 5.071 8.278 3.034 1.00 4.54 C ANISOU 1125 CB LEU A 333 568 605 553 15 -10 28 C ATOM 1126 CG LEU A 333 5.603 9.109 1.868 1.00 5.19 C ANISOU 1126 CG LEU A 333 643 664 664 18 26 87 C ATOM 1127 CD1 LEU A 333 6.913 9.755 2.217 1.00 6.40 C ANISOU 1127 CD1 LEU A 333 839 785 808 -56 106 36 C ATOM 1128 CD2 LEU A 333 5.759 8.273 0.636 1.00 6.06 C ANISOU 1128 CD2 LEU A 333 811 823 668 -1 -30 23 C ATOM 1129 N TYR A 334 3.555 5.554 3.905 1.00 4.47 N ANISOU 1129 N TYR A 334 608 490 598 89 81 3 N ATOM 1130 CA TYR A 334 3.414 4.611 5.023 1.00 4.16 C ANISOU 1130 CA TYR A 334 585 517 478 -10 38 -39 C ATOM 1131 C TYR A 334 4.429 3.484 4.842 1.00 4.42 C ANISOU 1131 C TYR A 334 595 571 510 30 17 14 C ATOM 1132 O TYR A 334 5.043 3.339 3.778 1.00 4.51 O ANISOU 1132 O TYR A 334 581 581 550 -47 164 5 O ATOM 1133 CB TYR A 334 1.995 4.057 5.159 1.00 4.91 C ANISOU 1133 CB TYR A 334 609 623 631 27 -23 62 C ATOM 1134 CG TYR A 334 1.569 3.168 4.006 1.00 4.24 C ANISOU 1134 CG TYR A 334 571 477 560 -72 82 -7 C ATOM 1135 CD1 TYR A 334 1.708 1.790 4.058 1.00 5.31 C ANISOU 1135 CD1 TYR A 334 749 628 640 96 25 118 C ATOM 1136 CD2 TYR A 334 1.066 3.717 2.838 1.00 5.39 C ANISOU 1136 CD2 TYR A 334 742 568 736 -2 -88 24 C ATOM 1137 CE1 TYR A 334 1.323 0.985 3.004 1.00 5.23 C ANISOU 1137 CE1 TYR A 334 603 566 817 -75 -29 65 C ATOM 1138 CE2 TYR A 334 0.678 2.934 1.777 1.00 6.00 C ANISOU 1138 CE2 TYR A 334 680 780 818 10 -98 4 C ATOM 1139 CZ TYR A 334 0.805 1.550 1.850 1.00 6.25 C ANISOU 1139 CZ TYR A 334 888 769 718 -80 0 49 C ATOM 1140 OH TYR A 334 0.433 0.769 0.776 1.00 6.45 O ANISOU 1140 OH TYR A 334 767 758 923 -112 -60 61 O ATOM 1141 N ASP A 335 4.595 2.684 5.882 1.00 4.54 N ANISOU 1141 N ASP A 335 647 540 538 8 102 56 N ATOM 1142 CA ASP A 335 5.566 1.603 5.870 1.00 4.76 C ANISOU 1142 CA ASP A 335 647 576 582 26 32 11 C ATOM 1143 C ASP A 335 4.939 0.377 5.196 1.00 4.08 C ANISOU 1143 C ASP A 335 473 533 544 5 15 7 C ATOM 1144 O ASP A 335 3.996 -0.226 5.722 1.00 5.56 O ANISOU 1144 O ASP A 335 769 684 658 -79 65 34 O ATOM 1145 CB ASP A 335 5.956 1.282 7.300 1.00 5.26 C ANISOU 1145 CB ASP A 335 734 627 638 -8 -2 -18 C ATOM 1146 CG ASP A 335 7.014 0.213 7.423 1.00 7.26 C ANISOU 1146 CG ASP A 335 1043 865 849 131 -13 -43 C ATOM 1147 OD1 ASP A 335 7.498 -0.379 6.422 1.00 6.81 O ANISOU 1147 OD1 ASP A 335 923 928 736 47 -27 43 O ATOM 1148 OD2 ASP A 335 7.453 -0.077 8.561 1.00 11.47 O ANISOU 1148 OD2 ASP A 335 1876 1493 990 240 -82 0 O ATOM 1149 N TYR A 336 5.453 0.012 4.023 1.00 4.48 N ANISOU 1149 N TYR A 336 574 546 579 -15 28 45 N ATOM 1150 CA TYR A 336 4.950 -1.152 3.294 1.00 4.18 C ANISOU 1150 CA TYR A 336 566 536 485 -25 27 33 C ATOM 1151 C TYR A 336 5.097 -2.450 4.102 1.00 4.67 C ANISOU 1151 C TYR A 336 672 497 606 -22 9 1 C ATOM 1152 O TYR A 336 4.372 -3.413 3.868 1.00 4.98 O ANISOU 1152 O TYR A 336 704 617 569 -145 60 29 O ATOM 1153 CB TYR A 336 5.680 -1.307 1.976 1.00 4.22 C ANISOU 1153 CB TYR A 336 654 444 503 -4 33 -57 C ATOM 1154 CG TYR A 336 5.246 -0.379 0.884 1.00 3.20 C ANISOU 1154 CG TYR A 336 387 413 413 -1 -15 -44 C ATOM 1155 CD1 TYR A 336 4.322 0.654 1.094 1.00 3.28 C ANISOU 1155 CD1 TYR A 336 527 449 269 -2 46 40 C ATOM 1156 CD2 TYR A 336 5.739 -0.559 -0.412 1.00 3.92 C ANISOU 1156 CD2 TYR A 336 458 517 512 105 -24 -84 C ATOM 1157 CE1 TYR A 336 3.937 1.482 0.033 1.00 2.97 C ANISOU 1157 CE1 TYR A 336 481 311 335 86 -66 -20 C ATOM 1158 CE2 TYR A 336 5.371 0.260 -1.448 1.00 4.27 C ANISOU 1158 CE2 TYR A 336 559 457 606 -26 14 -13 C ATOM 1159 CZ TYR A 336 4.463 1.265 -1.229 1.00 3.50 C ANISOU 1159 CZ TYR A 336 430 429 469 -12 34 -32 C ATOM 1160 OH TYR A 336 4.085 2.050 -2.292 1.00 3.83 O ANISOU 1160 OH TYR A 336 450 514 489 -11 46 18 O ATOM 1161 N GLY A 337 6.052 -2.486 5.023 1.00 5.52 N ANISOU 1161 N GLY A 337 738 600 757 -45 0 27 N ATOM 1162 CA GLY A 337 6.210 -3.642 5.897 1.00 6.34 C ANISOU 1162 CA GLY A 337 873 774 760 -22 -27 29 C ATOM 1163 C GLY A 337 6.993 -4.832 5.367 1.00 7.26 C ANISOU 1163 C GLY A 337 951 902 903 7 8 3 C ATOM 1164 O GLY A 337 7.218 -5.786 6.122 1.00 8.23 O ANISOU 1164 O GLY A 337 1176 886 1063 16 -6 -15 O ATOM 1165 N ASP A 338 7.439 -4.778 4.111 1.00 7.92 N ANISOU 1165 N ASP A 338 1099 977 931 8 18 12 N ATOM 1166 CA ASP A 338 8.231 -5.869 3.525 1.00 8.22 C ANISOU 1166 CA ASP A 338 1095 990 1036 -23 -17 24 C ATOM 1167 C ASP A 338 9.683 -5.766 3.974 1.00 8.95 C ANISOU 1167 C ASP A 338 1152 1108 1139 -26 12 55 C ATOM 1168 O ASP A 338 10.417 -4.885 3.549 1.00 8.58 O ANISOU 1168 O ASP A 338 1134 1026 1100 -68 9 115 O ATOM 1169 CB ASP A 338 8.136 -5.824 1.990 1.00 8.28 C ANISOU 1169 CB ASP A 338 1157 1003 983 -33 31 32 C ATOM 1170 CG ASP A 338 8.723 -7.059 1.314 1.00 9.18 C ANISOU 1170 CG ASP A 338 1197 1209 1082 24 -30 -26 C ATOM 1171 OD1 ASP A 338 9.504 -7.821 1.950 1.00 9.86 O ANISOU 1171 OD1 ASP A 338 1366 1165 1213 -4 -58 50 O ATOM 1172 OD2 ASP A 338 8.458 -7.338 0.113 1.00 8.65 O ANISOU 1172 OD2 ASP A 338 1082 1165 1039 -61 -59 -100 O ATOM 1173 N ARG A 339 10.091 -6.697 4.825 1.00 10.15 N ANISOU 1173 N ARG A 339 1339 1245 1270 9 -20 75 N ATOM 1174 CA ARG A 339 11.436 -6.724 5.363 1.00 11.44 C ANISOU 1174 CA ARG A 339 1431 1475 1441 -2 -10 42 C ATOM 1175 C ARG A 339 12.286 -7.855 4.768 1.00 11.66 C ANISOU 1175 C ARG A 339 1502 1480 1445 -12 -17 53 C ATOM 1176 O ARG A 339 13.404 -8.114 5.234 1.00 12.15 O ANISOU 1176 O ARG A 339 1533 1579 1503 24 17 103 O ATOM 1177 CB ARG A 339 11.329 -6.834 6.890 1.00 12.67 C ANISOU 1177 CB ARG A 339 1641 1652 1519 -28 -34 67 C ATOM 1178 CG ARG A 339 10.698 -5.562 7.521 1.00 15.73 C ANISOU 1178 CG ARG A 339 2001 1985 1988 90 -66 -30 C ATOM 1179 CD ARG A 339 10.016 -5.758 8.861 1.00 21.40 C ANISOU 1179 CD ARG A 339 2707 2813 2611 -36 90 61 C ATOM 1180 NE ARG A 339 9.559 -4.491 9.451 1.00 25.48 N ANISOU 1180 NE ARG A 339 3308 3060 3312 31 5 -65 N ATOM 1181 CZ ARG A 339 9.271 -4.305 10.748 1.00 28.01 C ANISOU 1181 CZ ARG A 339 3551 3556 3534 -2 10 -13 C ATOM 1182 NH1 ARG A 339 9.385 -5.300 11.618 1.00 29.57 N ANISOU 1182 NH1 ARG A 339 3756 3735 3742 -2 4 13 N ATOM 1183 NH2 ARG A 339 8.867 -3.113 11.179 1.00 28.91 N ANISOU 1183 NH2 ARG A 339 3660 3657 3666 4 8 -12 N ATOM 1184 N SER A 340 11.785 -8.492 3.712 1.00 11.95 N ANISOU 1184 N SER A 340 1578 1444 1515 11 8 36 N ATOM 1185 CA SER A 340 12.489 -9.609 3.070 1.00 12.31 C ANISOU 1185 CA SER A 340 1557 1540 1578 24 21 20 C ATOM 1186 C SER A 340 13.842 -9.221 2.482 1.00 11.96 C ANISOU 1186 C SER A 340 1498 1481 1563 23 6 15 C ATOM 1187 O SER A 340 13.952 -8.206 1.813 1.00 11.25 O ANISOU 1187 O SER A 340 1321 1397 1553 67 0 38 O ATOM 1188 CB SER A 340 11.635 -10.170 1.930 1.00 12.48 C ANISOU 1188 CB SER A 340 1589 1511 1638 3 -1 -9 C ATOM 1189 OG SER A 340 12.442 -10.979 1.081 1.00 15.35 O ANISOU 1189 OG SER A 340 1913 2009 1910 48 88 -18 O ATOM 1190 N LYS A 341 14.856 -10.064 2.688 1.00 12.18 N ANISOU 1190 N LYS A 341 1509 1528 1588 4 -8 10 N ATOM 1191 CA LYS A 341 16.182 -9.796 2.153 1.00 12.46 C ANISOU 1191 CA LYS A 341 1592 1553 1589 0 3 6 C ATOM 1192 C LYS A 341 16.124 -9.634 0.632 1.00 11.96 C ANISOU 1192 C LYS A 341 1519 1478 1547 1 -17 9 C ATOM 1193 O LYS A 341 16.735 -8.725 0.088 1.00 11.76 O ANISOU 1193 O LYS A 341 1515 1472 1481 22 -11 25 O ATOM 1194 CB LYS A 341 17.183 -10.898 2.566 1.00 13.06 C ANISOU 1194 CB LYS A 341 1647 1624 1691 -8 -3 25 C ATOM 1195 CG LYS A 341 17.711 -11.784 1.443 1.00 15.07 C ANISOU 1195 CG LYS A 341 1995 1872 1857 -12 25 -9 C ATOM 1196 CD LYS A 341 16.781 -12.953 1.154 1.00 16.57 C ANISOU 1196 CD LYS A 341 2129 2075 2091 -75 -21 2 C ATOM 1197 CE LYS A 341 17.378 -13.899 0.125 1.00 17.28 C ANISOU 1197 CE LYS A 341 2208 2177 2179 -2 18 -18 C ATOM 1198 NZ LYS A 341 16.313 -14.697 -0.561 1.00 18.23 N ANISOU 1198 NZ LYS A 341 2361 2275 2289 -42 -35 -5 N ATOM 1199 N ALA A 342 15.374 -10.505 -0.042 1.00 11.58 N ANISOU 1199 N ALA A 342 1485 1438 1475 22 -21 19 N ATOM 1200 CA ALA A 342 15.271 -10.485 -1.503 1.00 11.33 C ANISOU 1200 CA ALA A 342 1435 1407 1462 -7 -7 15 C ATOM 1201 C ALA A 342 14.637 -9.191 -1.978 1.00 10.57 C ANISOU 1201 C ALA A 342 1352 1304 1358 -5 8 -12 C ATOM 1202 O ALA A 342 15.049 -8.600 -2.982 1.00 10.81 O ANISOU 1202 O ALA A 342 1391 1287 1429 -50 27 -20 O ATOM 1203 CB ALA A 342 14.445 -11.661 -1.987 1.00 11.60 C ANISOU 1203 CB ALA A 342 1495 1414 1496 20 -32 0 C ATOM 1204 N SER A 343 13.611 -8.768 -1.265 1.00 10.10 N ANISOU 1204 N SER A 343 1267 1250 1321 -9 4 24 N ATOM 1205 CA SER A 343 12.902 -7.548 -1.610 1.00 9.41 C ANISOU 1205 CA SER A 343 1199 1148 1226 4 16 -8 C ATOM 1206 C SER A 343 13.801 -6.353 -1.418 1.00 8.77 C ANISOU 1206 C SER A 343 1098 1082 1151 23 26 -9 C ATOM 1207 O SER A 343 13.880 -5.502 -2.275 1.00 8.43 O ANISOU 1207 O SER A 343 1093 970 1139 -25 28 -29 O ATOM 1208 CB SER A 343 11.644 -7.401 -0.757 1.00 9.06 C ANISOU 1208 CB SER A 343 1096 1108 1236 -1 20 12 C ATOM 1209 OG SER A 343 10.652 -8.308 -1.198 1.00 9.59 O ANISOU 1209 OG SER A 343 1164 1202 1276 21 -49 -26 O ATOM 1210 N ILE A 344 14.488 -6.300 -0.291 1.00 9.46 N ANISOU 1210 N ILE A 344 1251 1110 1231 1 -7 0 N ATOM 1211 CA ILE A 344 15.381 -5.180 -0.004 1.00 9.63 C ANISOU 1211 CA ILE A 344 1205 1173 1279 -2 7 0 C ATOM 1212 C ILE A 344 16.581 -5.128 -0.957 1.00 9.77 C ANISOU 1212 C ILE A 344 1244 1186 1281 1 23 10 C ATOM 1213 O ILE A 344 17.058 -4.050 -1.313 1.00 10.09 O ANISOU 1213 O ILE A 344 1303 1194 1334 8 18 -3 O ATOM 1214 CB ILE A 344 15.817 -5.218 1.458 1.00 9.63 C ANISOU 1214 CB ILE A 344 1226 1165 1266 8 3 12 C ATOM 1215 CG1 ILE A 344 14.618 -4.854 2.349 1.00 11.46 C ANISOU 1215 CG1 ILE A 344 1533 1394 1424 54 20 17 C ATOM 1216 CG2 ILE A 344 16.998 -4.261 1.675 1.00 10.64 C ANISOU 1216 CG2 ILE A 344 1345 1324 1372 -14 26 -11 C ATOM 1217 CD1 ILE A 344 14.843 -5.117 3.807 1.00 12.49 C ANISOU 1217 CD1 ILE A 344 1752 1545 1449 -2 27 12 C ATOM 1218 N GLU A 345 17.062 -6.294 -1.374 1.00 10.04 N ANISOU 1218 N GLU A 345 1278 1237 1299 2 26 3 N ATOM 1219 CA GLU A 345 18.157 -6.382 -2.329 1.00 10.61 C ANISOU 1219 CA GLU A 345 1353 1337 1341 0 15 -6 C ATOM 1220 C GLU A 345 17.734 -5.767 -3.656 1.00 9.89 C ANISOU 1220 C GLU A 345 1243 1225 1289 14 26 -27 C ATOM 1221 O GLU A 345 18.477 -5.002 -4.269 1.00 10.11 O ANISOU 1221 O GLU A 345 1337 1227 1278 25 28 -65 O ATOM 1222 CB GLU A 345 18.511 -7.858 -2.513 1.00 11.26 C ANISOU 1222 CB GLU A 345 1475 1379 1423 1 -28 -8 C ATOM 1223 CG GLU A 345 19.773 -8.172 -3.272 1.00 14.53 C ANISOU 1223 CG GLU A 345 1842 1941 1735 3 33 -21 C ATOM 1224 CD GLU A 345 20.138 -9.641 -3.144 1.00 19.05 C ANISOU 1224 CD GLU A 345 2602 2202 2434 19 -4 21 C ATOM 1225 OE1 GLU A 345 20.075 -10.167 -2.007 1.00 21.58 O ANISOU 1225 OE1 GLU A 345 3007 2666 2527 -33 12 58 O ATOM 1226 OE2 GLU A 345 20.483 -10.278 -4.168 1.00 21.75 O ANISOU 1226 OE2 GLU A 345 2953 2710 2601 18 53 -64 O ATOM 1227 N ALA A 346 16.522 -6.092 -4.088 1.00 9.78 N ANISOU 1227 N ALA A 346 1284 1212 1218 12 12 -24 N ATOM 1228 CA ALA A 346 15.990 -5.589 -5.342 1.00 9.42 C ANISOU 1228 CA ALA A 346 1206 1178 1192 17 24 -23 C ATOM 1229 C ALA A 346 15.472 -4.157 -5.233 1.00 9.10 C ANISOU 1229 C ALA A 346 1205 1110 1139 -24 10 -1 C ATOM 1230 O ALA A 346 15.386 -3.441 -6.235 1.00 9.74 O ANISOU 1230 O ALA A 346 1381 1180 1139 -57 8 -52 O ATOM 1231 CB ALA A 346 14.886 -6.497 -5.812 1.00 9.41 C ANISOU 1231 CB ALA A 346 1203 1180 1192 8 21 -4 C ATOM 1232 N HIS A 347 15.111 -3.750 -4.020 1.00 8.54 N ANISOU 1232 N HIS A 347 1076 1053 1114 -10 13 5 N ATOM 1233 CA HIS A 347 14.505 -2.443 -3.795 1.00 8.22 C ANISOU 1233 CA HIS A 347 1091 1005 1027 -27 35 4 C ATOM 1234 C HIS A 347 15.049 -1.835 -2.513 1.00 7.58 C ANISOU 1234 C HIS A 347 946 936 995 -15 53 5 C ATOM 1235 O HIS A 347 14.408 -1.904 -1.472 1.00 7.30 O ANISOU 1235 O HIS A 347 1026 860 885 -20 46 -43 O ATOM 1236 CB HIS A 347 12.989 -2.602 -3.685 1.00 8.44 C ANISOU 1236 CB HIS A 347 1125 988 1091 12 0 8 C ATOM 1237 CG HIS A 347 12.361 -3.332 -4.828 1.00 9.47 C ANISOU 1237 CG HIS A 347 1266 1204 1128 0 10 3 C ATOM 1238 ND1 HIS A 347 12.088 -2.732 -6.041 1.00 11.70 N ANISOU 1238 ND1 HIS A 347 1620 1434 1391 9 -165 32 N ATOM 1239 CD2 HIS A 347 11.944 -4.616 -4.940 1.00 9.89 C ANISOU 1239 CD2 HIS A 347 1261 1325 1171 -34 -24 -25 C ATOM 1240 CE1 HIS A 347 11.526 -3.616 -6.847 1.00 11.03 C ANISOU 1240 CE1 HIS A 347 1547 1395 1245 -16 -76 13 C ATOM 1241 NE2 HIS A 347 11.437 -4.769 -6.208 1.00 10.34 N ANISOU 1241 NE2 HIS A 347 1355 1391 1180 -31 -85 -30 N ATOM 1242 N PRO A 348 16.248 -1.264 -2.578 1.00 7.23 N ANISOU 1242 N PRO A 348 943 889 915 -29 9 -25 N ATOM 1243 CA PRO A 348 16.889 -0.703 -1.390 1.00 6.99 C ANISOU 1243 CA PRO A 348 915 853 885 -25 7 -23 C ATOM 1244 C PRO A 348 16.099 0.382 -0.692 1.00 6.11 C ANISOU 1244 C PRO A 348 769 788 764 -27 11 -12 C ATOM 1245 O PRO A 348 16.332 0.606 0.507 1.00 6.60 O ANISOU 1245 O PRO A 348 857 810 841 -41 -24 -66 O ATOM 1246 CB PRO A 348 18.212 -0.165 -1.935 1.00 6.62 C ANISOU 1246 CB PRO A 348 826 826 863 -21 -28 -50 C ATOM 1247 CG PRO A 348 18.491 -1.010 -3.135 1.00 7.62 C ANISOU 1247 CG PRO A 348 1005 956 932 -2 58 -3 C ATOM 1248 CD PRO A 348 17.134 -1.208 -3.757 1.00 7.60 C ANISOU 1248 CD PRO A 348 1026 930 932 -32 19 -34 C ATOM 1249 N TRP A 349 15.177 1.017 -1.400 1.00 5.78 N ANISOU 1249 N TRP A 349 744 736 715 0 44 3 N ATOM 1250 CA TRP A 349 14.332 2.057 -0.809 1.00 5.68 C ANISOU 1250 CA TRP A 349 740 682 736 -35 20 -22 C ATOM 1251 C TRP A 349 13.434 1.496 0.298 1.00 5.92 C ANISOU 1251 C TRP A 349 767 718 762 -11 61 -37 C ATOM 1252 O TRP A 349 12.918 2.251 1.118 1.00 6.42 O ANISOU 1252 O TRP A 349 948 715 775 26 -25 -141 O ATOM 1253 CB TRP A 349 13.509 2.808 -1.867 1.00 5.65 C ANISOU 1253 CB TRP A 349 753 711 681 -63 20 -9 C ATOM 1254 CG TRP A 349 12.757 1.919 -2.804 1.00 4.99 C ANISOU 1254 CG TRP A 349 460 710 724 -17 -3 -19 C ATOM 1255 CD1 TRP A 349 13.152 1.541 -4.053 1.00 5.95 C ANISOU 1255 CD1 TRP A 349 814 812 635 -19 -37 77 C ATOM 1256 CD2 TRP A 349 11.496 1.287 -2.573 1.00 4.71 C ANISOU 1256 CD2 TRP A 349 516 608 665 -23 -33 -5 C ATOM 1257 NE1 TRP A 349 12.212 0.716 -4.618 1.00 6.49 N ANISOU 1257 NE1 TRP A 349 835 839 789 51 -52 62 N ATOM 1258 CE2 TRP A 349 11.183 0.545 -3.731 1.00 4.94 C ANISOU 1258 CE2 TRP A 349 591 609 678 89 -31 76 C ATOM 1259 CE3 TRP A 349 10.595 1.273 -1.505 1.00 4.15 C ANISOU 1259 CE3 TRP A 349 469 628 480 -12 -123 -10 C ATOM 1260 CZ2 TRP A 349 10.016 -0.195 -3.842 1.00 4.86 C ANISOU 1260 CZ2 TRP A 349 614 634 597 -2 -47 -47 C ATOM 1261 CZ3 TRP A 349 9.433 0.548 -1.617 1.00 3.87 C ANISOU 1261 CZ3 TRP A 349 474 479 515 64 -33 -3 C ATOM 1262 CH2 TRP A 349 9.161 -0.199 -2.770 1.00 4.12 C ANISOU 1262 CH2 TRP A 349 501 432 632 128 -78 -52 C ATOM 1263 N LEU A 350 13.272 0.172 0.358 1.00 6.02 N ANISOU 1263 N LEU A 350 863 671 754 20 3 -50 N ATOM 1264 CA LEU A 350 12.433 -0.440 1.395 1.00 6.05 C ANISOU 1264 CA LEU A 350 755 728 815 14 1 -10 C ATOM 1265 C LEU A 350 13.040 -0.296 2.790 1.00 7.74 C ANISOU 1265 C LEU A 350 1041 951 947 36 6 14 C ATOM 1266 O LEU A 350 12.344 -0.401 3.798 1.00 7.83 O ANISOU 1266 O LEU A 350 1033 1065 877 112 -55 78 O ATOM 1267 CB LEU A 350 12.186 -1.924 1.105 1.00 6.07 C ANISOU 1267 CB LEU A 350 767 737 801 3 -7 -7 C ATOM 1268 CG LEU A 350 11.013 -2.217 0.184 1.00 5.80 C ANISOU 1268 CG LEU A 350 778 659 765 2 11 7 C ATOM 1269 CD1 LEU A 350 11.069 -3.683 -0.226 1.00 6.67 C ANISOU 1269 CD1 LEU A 350 965 711 855 -15 -28 -50 C ATOM 1270 CD2 LEU A 350 9.712 -1.898 0.869 1.00 6.62 C ANISOU 1270 CD2 LEU A 350 870 742 902 4 25 -76 C ATOM 1271 N LYS A 351 14.330 -0.012 2.831 1.00 9.69 N ANISOU 1271 N LYS A 351 1268 1205 1207 1 -17 -13 N ATOM 1272 CA LYS A 351 15.040 0.121 4.088 1.00 11.67 C ANISOU 1272 CA LYS A 351 1507 1485 1442 -5 -50 1 C ATOM 1273 C LYS A 351 14.882 1.491 4.743 1.00 12.45 C ANISOU 1273 C LYS A 351 1622 1572 1536 2 -38 -38 C ATOM 1274 O LYS A 351 15.294 1.690 5.892 1.00 13.08 O ANISOU 1274 O LYS A 351 1762 1683 1523 27 -100 -32 O ATOM 1275 CB LYS A 351 16.517 -0.161 3.836 1.00 12.16 C ANISOU 1275 CB LYS A 351 1514 1540 1565 6 -10 -9 C ATOM 1276 CG LYS A 351 17.370 -0.035 5.041 1.00 14.86 C ANISOU 1276 CG LYS A 351 1985 1903 1757 -60 -31 2 C ATOM 1277 CD LYS A 351 18.703 -0.643 4.804 1.00 17.51 C ANISOU 1277 CD LYS A 351 2252 2219 2182 46 1 7 C ATOM 1278 CE LYS A 351 18.653 -2.156 4.812 1.00 18.79 C ANISOU 1278 CE LYS A 351 2445 2305 2386 -11 0 -8 C ATOM 1279 NZ LYS A 351 19.976 -2.700 5.255 1.00 19.43 N ANISOU 1279 NZ LYS A 351 2458 2461 2461 1 -5 1 N ATOM 1280 N HIS A 352 14.294 2.439 4.032 1.00 13.04 N ANISOU 1280 N HIS A 352 1688 1647 1616 -11 -61 -24 N ATOM 1281 CA HIS A 352 14.197 3.800 4.544 1.00 14.05 C ANISOU 1281 CA HIS A 352 1805 1737 1795 -2 0 -16 C ATOM 1282 C HIS A 352 12.767 4.316 4.615 1.00 14.48 C ANISOU 1282 C HIS A 352 1878 1783 1840 12 -17 -7 C ATOM 1283 O HIS A 352 12.499 5.393 5.179 1.00 14.90 O ANISOU 1283 O HIS A 352 1932 1829 1898 51 42 1 O ATOM 1284 CB HIS A 352 15.091 4.701 3.697 1.00 14.50 C ANISOU 1284 CB HIS A 352 1876 1807 1824 -6 40 -4 C ATOM 1285 CG HIS A 352 16.510 4.231 3.627 1.00 15.80 C ANISOU 1285 CG HIS A 352 1979 1976 2045 25 4 -4 C ATOM 1286 ND1 HIS A 352 17.449 4.557 4.580 1.00 16.32 N ANISOU 1286 ND1 HIS A 352 1944 2171 2084 -16 -6 -22 N ATOM 1287 CD2 HIS A 352 17.145 3.441 2.728 1.00 16.76 C ANISOU 1287 CD2 HIS A 352 2138 2096 2131 -3 36 -55 C ATOM 1288 CE1 HIS A 352 18.608 4.006 4.263 1.00 17.27 C ANISOU 1288 CE1 HIS A 352 2191 2201 2167 79 6 -37 C ATOM 1289 NE2 HIS A 352 18.449 3.316 3.147 1.00 17.38 N ANISOU 1289 NE2 HIS A 352 2174 2236 2192 40 -5 -20 N ATOM 1290 OXT HIS A 352 11.864 3.623 4.165 1.00 14.73 O ANISOU 1290 OXT HIS A 352 1816 1819 1960 65 7 -34 O TER 1291 HIS A 352 ATOM 1292 N ARG B 17 11.132 -7.415 -7.176 1.00 12.17 N ANISOU 1292 N ARG B 17 1501 1547 1573 14 2 21 N ATOM 1293 CA ARG B 17 9.710 -7.579 -6.734 1.00 11.97 C ANISOU 1293 CA ARG B 17 1502 1539 1506 42 8 1 C ATOM 1294 C ARG B 17 9.622 -7.507 -5.217 1.00 10.58 C ANISOU 1294 C ARG B 17 1304 1340 1373 47 -8 -23 C ATOM 1295 O ARG B 17 10.553 -7.897 -4.513 1.00 11.61 O ANISOU 1295 O ARG B 17 1469 1440 1503 92 -50 -34 O ATOM 1296 CB ARG B 17 9.137 -8.924 -7.192 1.00 12.87 C ANISOU 1296 CB ARG B 17 1606 1640 1641 6 11 -3 C ATOM 1297 CG ARG B 17 9.151 -9.170 -8.700 1.00 15.64 C ANISOU 1297 CG ARG B 17 2059 2002 1879 -8 35 -47 C ATOM 1298 CD ARG B 17 8.186 -8.303 -9.447 1.00 18.85 C ANISOU 1298 CD ARG B 17 2336 2366 2459 59 -33 67 C ATOM 1299 NE ARG B 17 8.162 -8.555 -10.879 1.00 21.66 N ANISOU 1299 NE ARG B 17 2781 2735 2713 -32 -5 -45 N ATOM 1300 CZ ARG B 17 7.290 -7.991 -11.706 1.00 23.61 C ANISOU 1300 CZ ARG B 17 2988 2956 3028 14 -40 37 C ATOM 1301 NH1 ARG B 17 6.379 -7.152 -11.236 1.00 24.83 N ANISOU 1301 NH1 ARG B 17 3064 3137 3233 51 -25 -30 N ATOM 1302 NH2 ARG B 17 7.320 -8.265 -12.998 1.00 24.67 N ANISOU 1302 NH2 ARG B 17 3131 3118 3124 -23 -33 24 N ATOM 1303 N HIS B 18 8.567 -6.889 -4.715 1.00 8.89 N ANISOU 1303 N HIS B 18 1139 1089 1149 6 -13 -34 N ATOM 1304 CA HIS B 18 8.252 -6.938 -3.305 1.00 7.64 C ANISOU 1304 CA HIS B 18 868 988 1044 -26 -3 17 C ATOM 1305 C HIS B 18 6.741 -7.087 -3.093 1.00 7.08 C ANISOU 1305 C HIS B 18 809 932 948 23 -19 -21 C ATOM 1306 O HIS B 18 5.962 -7.198 -4.044 1.00 7.15 O ANISOU 1306 O HIS B 18 740 1006 969 -60 45 16 O ATOM 1307 CB HIS B 18 8.700 -5.634 -2.648 1.00 7.32 C ANISOU 1307 CB HIS B 18 846 964 968 -1 -49 -41 C ATOM 1308 CG HIS B 18 7.964 -4.439 -3.162 1.00 6.05 C ANISOU 1308 CG HIS B 18 649 828 820 -70 -46 -33 C ATOM 1309 ND1 HIS B 18 6.767 -4.021 -2.620 1.00 6.83 N ANISOU 1309 ND1 HIS B 18 854 812 929 44 -6 -8 N ATOM 1310 CD2 HIS B 18 8.212 -3.616 -4.208 1.00 5.48 C ANISOU 1310 CD2 HIS B 18 498 734 848 -40 9 -76 C ATOM 1311 CE1 HIS B 18 6.307 -2.997 -3.318 1.00 7.17 C ANISOU 1311 CE1 HIS B 18 919 759 1042 10 66 73 C ATOM 1312 NE2 HIS B 18 7.169 -2.728 -4.283 1.00 5.49 N ANISOU 1312 NE2 HIS B 18 749 576 758 -18 -31 -31 N ATOM 1313 N ARG B 19 6.357 -7.092 -1.831 1.00 6.79 N ANISOU 1313 N ARG B 19 716 911 950 -33 -14 -19 N ATOM 1314 CA ARG B 19 4.959 -7.061 -1.453 1.00 7.02 C ANISOU 1314 CA ARG B 19 807 930 928 -1 39 -43 C ATOM 1315 C ARG B 19 4.773 -6.012 -0.349 1.00 6.34 C ANISOU 1315 C ARG B 19 700 833 875 -42 -29 -44 C ATOM 1316 O ARG B 19 5.636 -5.122 -0.133 1.00 5.87 O ANISOU 1316 O ARG B 19 636 786 807 -86 -11 -125 O ATOM 1317 CB ARG B 19 4.472 -8.438 -1.024 1.00 7.94 C ANISOU 1317 CB ARG B 19 972 1005 1039 -15 43 -80 C ATOM 1318 CG ARG B 19 5.223 -9.047 0.106 1.00 10.54 C ANISOU 1318 CG ARG B 19 1324 1377 1300 5 -36 49 C ATOM 1319 CD ARG B 19 5.013 -10.552 0.244 1.00 13.45 C ANISOU 1319 CD ARG B 19 1724 1566 1819 -44 -52 65 C ATOM 1320 NE ARG B 19 5.594 -11.302 -0.864 1.00 16.47 N ANISOU 1320 NE ARG B 19 2166 2030 2060 -20 -27 -42 N ATOM 1321 CZ ARG B 19 6.897 -11.463 -1.078 1.00 19.22 C ANISOU 1321 CZ ARG B 19 2362 2445 2494 37 -5 -13 C ATOM 1322 NH1 ARG B 19 7.803 -10.929 -0.260 1.00 19.86 N ANISOU 1322 NH1 ARG B 19 2423 2491 2631 23 -52 -9 N ATOM 1323 NH2 ARG B 19 7.302 -12.168 -2.124 1.00 21.43 N ANISOU 1323 NH2 ARG B 19 2693 2752 2697 69 -1 -59 N HETATM 1324 N MLZ B 20 3.617 -6.042 0.333 1.00 4.42 N ANISOU 1324 N MLZ B 20 507 619 551 25 -16 55 N HETATM 1325 CA MLZ B 20 3.308 -5.258 1.507 1.00 5.12 C ANISOU 1325 CA MLZ B 20 576 658 711 -57 -4 17 C HETATM 1326 CB MLZ B 20 2.292 -4.156 1.219 1.00 5.99 C ANISOU 1326 CB MLZ B 20 711 741 824 -1 -11 29 C HETATM 1327 CG MLZ B 20 2.729 -3.154 0.173 1.00 7.09 C ANISOU 1327 CG MLZ B 20 864 858 969 -70 -11 45 C HETATM 1328 CD MLZ B 20 1.584 -2.231 -0.283 1.00 9.21 C ANISOU 1328 CD MLZ B 20 1049 1118 1330 -12 47 74 C HETATM 1329 CE MLZ B 20 2.085 -1.650 -1.594 1.00 11.14 C ANISOU 1329 CE MLZ B 20 1276 1357 1599 -85 35 180 C HETATM 1330 NZ MLZ B 20 1.180 -1.000 -2.467 1.00 13.04 N ANISOU 1330 NZ MLZ B 20 1558 1843 1553 -83 15 182 N HETATM 1331 CM MLZ B 20 1.707 -0.310 -3.618 1.00 9.89 C ANISOU 1331 CM MLZ B 20 1168 1453 1136 -48 -14 0 C HETATM 1332 C MLZ B 20 2.734 -6.240 2.490 1.00 5.78 C ANISOU 1332 C MLZ B 20 759 707 727 -26 -17 24 C HETATM 1333 O MLZ B 20 2.064 -7.180 2.113 1.00 5.32 O ANISOU 1333 O MLZ B 20 598 648 776 -40 -55 -22 O ATOM 1334 N VAL B 21 3.131 -5.885 3.831 1.00 7.49 N ANISOU 1334 N VAL B 21 1039 977 831 -64 -27 27 N ATOM 1335 CA VAL B 21 2.635 -6.807 4.906 1.00 7.65 C ANISOU 1335 CA VAL B 21 923 974 1007 -73 5 85 C ATOM 1336 C VAL B 21 2.211 -5.965 6.085 1.00 8.66 C ANISOU 1336 C VAL B 21 1136 1108 1047 -64 -26 57 C ATOM 1337 O VAL B 21 2.946 -5.072 6.503 1.00 7.53 O ANISOU 1337 O VAL B 21 1003 956 902 -227 -16 126 O ATOM 1338 CB VAL B 21 3.749 -7.732 5.408 1.00 8.44 C ANISOU 1338 CB VAL B 21 1100 1024 1082 -9 -10 99 C ATOM 1339 CG1 VAL B 21 3.262 -8.502 6.598 1.00 9.33 C ANISOU 1339 CG1 VAL B 21 1128 1231 1184 10 31 119 C ATOM 1340 CG2 VAL B 21 4.208 -8.639 4.324 1.00 8.95 C ANISOU 1340 CG2 VAL B 21 1074 1139 1187 0 -26 77 C ATOM 1341 N LEU B 22 0.975 -6.141 6.538 1.00 9.37 N ANISOU 1341 N LEU B 22 1051 1232 1277 -61 -57 77 N ATOM 1342 CA LEU B 22 0.514 -5.519 7.775 1.00 11.62 C ANISOU 1342 CA LEU B 22 1454 1497 1464 -49 -14 27 C ATOM 1343 C LEU B 22 0.959 -6.236 9.048 1.00 14.58 C ANISOU 1343 C LEU B 22 1839 1886 1813 30 21 88 C ATOM 1344 O LEU B 22 0.756 -7.432 9.176 1.00 14.52 O ANISOU 1344 O LEU B 22 1878 1944 1694 88 52 177 O ATOM 1345 CB LEU B 22 -1.004 -5.465 7.802 1.00 11.42 C ANISOU 1345 CB LEU B 22 1432 1428 1478 7 -24 9 C ATOM 1346 CG LEU B 22 -1.582 -4.761 9.023 1.00 11.29 C ANISOU 1346 CG LEU B 22 1489 1445 1355 -70 -6 34 C ATOM 1347 CD1 LEU B 22 -1.010 -3.341 9.154 1.00 13.68 C ANISOU 1347 CD1 LEU B 22 1912 1598 1687 -13 27 -31 C ATOM 1348 CD2 LEU B 22 -3.095 -4.760 8.993 1.00 11.83 C ANISOU 1348 CD2 LEU B 22 1593 1524 1377 64 -76 -97 C ATOM 1349 N ARG B 23 1.490 -5.463 9.986 1.00 18.88 N ANISOU 1349 N ARG B 23 2370 2474 2329 -21 -8 0 N ATOM 1350 CA ARG B 23 1.895 -5.975 11.299 1.00 22.01 C ANISOU 1350 CA ARG B 23 2812 2823 2726 9 -44 40 C ATOM 1351 C ARG B 23 0.973 -5.471 12.425 1.00 24.62 C ANISOU 1351 C ARG B 23 3137 3145 3072 54 0 -34 C ATOM 1352 O ARG B 23 0.806 -4.258 12.605 1.00 25.59 O ANISOU 1352 O ARG B 23 3313 3208 3202 20 -57 -49 O ATOM 1353 CB ARG B 23 3.343 -5.583 11.609 1.00 22.28 C ANISOU 1353 CB ARG B 23 2823 2856 2785 -8 -17 -8 C ATOM 1354 CG ARG B 23 4.241 -5.429 10.381 1.00 23.09 C ANISOU 1354 CG ARG B 23 2961 2920 2892 -13 7 20 C ATOM 1355 CD ARG B 23 5.688 -5.808 10.630 1.00 24.09 C ANISOU 1355 CD ARG B 23 3026 3019 3107 -12 0 -21 C ATOM 1356 NE ARG B 23 5.805 -7.252 10.822 1.00 23.76 N ANISOU 1356 NE ARG B 23 3012 3017 2998 14 -48 25 N ATOM 1357 CZ ARG B 23 6.145 -8.119 9.878 1.00 23.86 C ANISOU 1357 CZ ARG B 23 2995 3059 3010 29 0 21 C ATOM 1358 NH1 ARG B 23 6.460 -7.723 8.647 1.00 22.70 N ANISOU 1358 NH1 ARG B 23 2713 3016 2894 40 -61 54 N ATOM 1359 NH2 ARG B 23 6.190 -9.406 10.178 1.00 25.70 N ANISOU 1359 NH2 ARG B 23 3323 3206 3234 -6 25 34 N ATOM 1360 N ASP B 24 0.398 -6.430 13.156 1.00 27.24 N ANISOU 1360 N ASP B 24 3453 3440 3457 -6 -3 2 N ATOM 1361 CA ASP B 24 -0.464 -6.266 14.353 1.00 29.33 C ANISOU 1361 CA ASP B 24 3711 3725 3706 0 11 -5 C ATOM 1362 C ASP B 24 -0.699 -4.866 14.940 1.00 30.60 C ANISOU 1362 C ASP B 24 3880 3871 3876 -2 0 -10 C ATOM 1363 O ASP B 24 0.212 -4.247 15.492 1.00 30.89 O ANISOU 1363 O ASP B 24 3917 3949 3868 -24 -27 -11 O ATOM 1364 CB ASP B 24 0.104 -7.153 15.463 1.00 30.01 C ANISOU 1364 CB ASP B 24 3806 3797 3796 8 -8 -5 C ATOM 1365 CG ASP B 24 -0.969 -7.871 16.244 1.00 31.85 C ANISOU 1365 CG ASP B 24 4032 4034 4036 -17 11 5 C ATOM 1366 OD1 ASP B 24 -1.858 -7.194 16.813 1.00 34.08 O ANISOU 1366 OD1 ASP B 24 4298 4215 4433 75 54 -48 O ATOM 1367 OD2 ASP B 24 -1.000 -9.120 16.352 1.00 33.39 O ANISOU 1367 OD2 ASP B 24 4311 4106 4268 22 -6 -37 O ATOM 1368 N ASN B 25 -1.946 -4.404 14.852 1.00 31.86 N ANISOU 1368 N ASN B 25 4024 4041 4038 2 -4 4 N ATOM 1369 CA ASN B 25 -2.373 -3.115 15.398 1.00 32.68 C ANISOU 1369 CA ASN B 25 4141 4136 4140 4 0 -6 C ATOM 1370 C ASN B 25 -3.806 -3.236 15.908 1.00 33.10 C ANISOU 1370 C ASN B 25 4190 4190 4193 1 0 0 C ATOM 1371 O ASN B 25 -4.678 -2.443 15.541 1.00 33.56 O ANISOU 1371 O ASN B 25 4231 4233 4286 26 -14 0 O ATOM 1372 CB ASN B 25 -2.280 -1.996 14.347 1.00 33.10 C ANISOU 1372 CB ASN B 25 4193 4187 4196 0 2 8 C ATOM 1373 CG ASN B 25 -2.280 -2.517 12.926 1.00 34.52 C ANISOU 1373 CG ASN B 25 4378 4372 4363 -8 1 -9 C ATOM 1374 OD1 ASN B 25 -3.275 -2.410 12.213 1.00 36.59 O ANISOU 1374 OD1 ASN B 25 4651 4690 4561 70 -77 11 O ATOM 1375 ND2 ASN B 25 -1.155 -3.077 12.503 1.00 36.08 N ANISOU 1375 ND2 ASN B 25 4563 4570 4574 4 9 -1 N ATOM 1376 N TYR B 26 -4.043 -4.229 16.760 1.00 33.30 N ANISOU 1376 N TYR B 26 4220 4215 4216 0 0 4 N ATOM 1377 CA TYR B 26 -5.392 -4.515 17.228 1.00 33.52 C ANISOU 1377 CA TYR B 26 4242 4246 4249 0 -1 -1 C ATOM 1378 C TYR B 26 -6.069 -3.300 17.839 1.00 33.48 C ANISOU 1378 C TYR B 26 4238 4238 4242 0 -3 -1 C ATOM 1379 O TYR B 26 -5.820 -2.961 18.997 1.00 33.84 O ANISOU 1379 O TYR B 26 4275 4306 4275 -10 -5 -6 O ATOM 1380 CB TYR B 26 -5.408 -5.669 18.225 1.00 34.00 C ANISOU 1380 CB TYR B 26 4307 4299 4311 5 -1 9 C ATOM 1381 CG TYR B 26 -6.672 -6.469 18.084 1.00 34.99 C ANISOU 1381 CG TYR B 26 4402 4426 4465 -28 -8 5 C ATOM 1382 CD1 TYR B 26 -6.789 -7.437 17.094 1.00 35.65 C ANISOU 1382 CD1 TYR B 26 4531 4512 4502 -4 6 -17 C ATOM 1383 CD2 TYR B 26 -7.769 -6.221 18.897 1.00 35.85 C ANISOU 1383 CD2 TYR B 26 4518 4551 4552 4 20 -15 C ATOM 1384 CE1 TYR B 26 -7.954 -8.161 16.937 1.00 36.14 C ANISOU 1384 CE1 TYR B 26 4567 4576 4586 -19 0 -22 C ATOM 1385 CE2 TYR B 26 -8.939 -6.936 18.746 1.00 36.23 C ANISOU 1385 CE2 TYR B 26 4561 4598 4606 -20 11 -12 C ATOM 1386 CZ TYR B 26 -9.026 -7.908 17.766 1.00 36.31 C ANISOU 1386 CZ TYR B 26 4577 4600 4617 -12 4 -16 C ATOM 1387 OH TYR B 26 -10.192 -8.623 17.617 1.00 36.33 O ANISOU 1387 OH TYR B 26 4597 4582 4622 -25 6 -6 O ATOM 1388 OXT TYR B 26 -6.879 -2.663 17.161 1.00 34.22 O ANISOU 1388 OXT TYR B 26 4331 4292 4375 13 -25 16 O TER 1389 TYR B 26 ATOM 1390 N ARG E 192 32.804 0.378 20.927 1.00 53.51 N ANISOU 1390 N ARG E 192 6781 6770 6780 1 4 1 N ATOM 1391 CA ARG E 192 32.411 1.471 19.988 1.00 53.44 C ANISOU 1391 CA ARG E 192 6773 6760 6772 -10 0 0 C ATOM 1392 C ARG E 192 33.201 2.635 20.027 1.00 52.74 C ANISOU 1392 C ARG E 192 6670 6687 6680 5 8 1 C ATOM 1393 O ARG E 192 32.708 3.679 20.466 1.00 52.88 O ANISOU 1393 O ARG E 192 6701 6688 6702 -4 3 -6 O ATOM 1394 CB ARG E 192 31.139 2.141 20.407 1.00 53.82 C ANISOU 1394 CB ARG E 192 6823 6807 6817 10 15 4 C ATOM 1395 CG ARG E 192 29.968 1.629 19.702 1.00 55.06 C ANISOU 1395 CG ARG E 192 6957 6991 6973 -27 -2 -20 C ATOM 1396 CD ARG E 192 29.138 2.705 19.031 1.00 56.62 C ANISOU 1396 CD ARG E 192 7205 7142 7164 37 -2 19 C ATOM 1397 NE ARG E 192 27.780 2.249 18.739 1.00 57.99 N ANISOU 1397 NE ARG E 192 7305 7337 7389 -7 5 7 N ATOM 1398 CZ ARG E 192 27.317 1.972 17.527 1.00 59.27 C ANISOU 1398 CZ ARG E 192 7529 7507 7482 4 -20 -11 C ATOM 1399 NH1 ARG E 192 28.097 2.099 16.470 1.00 59.68 N ANISOU 1399 NH1 ARG E 192 7544 7558 7572 -4 6 0 N ATOM 1400 NH2 ARG E 192 26.066 1.566 17.355 1.00 60.01 N ANISOU 1400 NH2 ARG E 192 7579 7608 7611 -9 1 -5 N ATOM 1401 N LYS E 193 34.391 2.576 19.541 1.00 51.74 N ANISOU 1401 N LYS E 193 6567 6537 6554 -8 -5 -1 N ATOM 1402 CA LYS E 193 35.002 3.796 19.712 1.00 50.84 C ANISOU 1402 CA LYS E 193 6448 6451 6418 3 5 3 C ATOM 1403 C LYS E 193 34.806 3.560 21.216 1.00 49.56 C ANISOU 1403 C LYS E 193 6283 6257 6288 3 0 -19 C ATOM 1404 O LYS E 193 34.681 2.413 21.660 1.00 49.66 O ANISOU 1404 O LYS E 193 6295 6294 6276 -8 1 2 O ATOM 1405 CB LYS E 193 34.106 4.926 19.145 1.00 51.05 C ANISOU 1405 CB LYS E 193 6467 6458 6470 1 5 0 C ATOM 1406 CG LYS E 193 33.716 4.787 17.644 1.00 51.65 C ANISOU 1406 CG LYS E 193 6541 6563 6521 -9 -2 -10 C ATOM 1407 CD LYS E 193 32.966 6.032 17.102 1.00 52.38 C ANISOU 1407 CD LYS E 193 6628 6620 6652 9 -6 -2 C ATOM 1408 CE LYS E 193 32.999 6.146 15.570 1.00 52.93 C ANISOU 1408 CE LYS E 193 6716 6703 6692 2 1 -1 C ATOM 1409 NZ LYS E 193 32.699 7.527 15.086 1.00 53.20 N ATOM 1410 N SER E 194 34.765 4.603 22.007 1.00 47.92 N ANISOU 1410 N SER E 194 6069 6088 6049 1 5 19 N ATOM 1411 CA SER E 194 34.584 4.392 23.419 1.00 46.53 C ANISOU 1411 CA SER E 194 5883 5885 5911 12 5 -6 C ATOM 1412 C SER E 194 33.517 5.364 23.888 1.00 45.08 C ANISOU 1412 C SER E 194 5717 5724 5684 -13 11 14 C ATOM 1413 O SER E 194 33.182 6.300 23.166 1.00 44.97 O ANISOU 1413 O SER E 194 5690 5705 5688 6 2 4 O ATOM 1414 CB SER E 194 35.915 4.589 24.126 1.00 46.53 C ANISOU 1414 CB SER E 194 5886 5901 5892 1 0 2 C ATOM 1415 OG SER E 194 36.882 3.692 23.605 1.00 46.78 O ANISOU 1415 OG SER E 194 5933 5915 5923 -4 11 -10 O ATOM 1416 N LYS E 195 32.945 5.128 25.063 1.00 43.24 N ANISOU 1416 N LYS E 195 5464 5465 5499 15 -4 -10 N ATOM 1417 CA LYS E 195 31.932 6.044 25.571 1.00 41.76 C ANISOU 1417 CA LYS E 195 5293 5281 5290 -12 -2 5 C ATOM 1418 C LYS E 195 32.454 7.464 25.414 1.00 39.64 C ANISOU 1418 C LYS E 195 5012 5034 5014 2 -16 -7 C ATOM 1419 O LYS E 195 31.950 8.242 24.607 1.00 39.58 O ANISOU 1419 O LYS E 195 5014 5010 5012 0 2 0 O ATOM 1420 CB LYS E 195 31.609 5.780 27.039 1.00 41.72 C ANISOU 1420 CB LYS E 195 5283 5282 5284 2 2 -3 C ATOM 1421 CG LYS E 195 30.660 6.828 27.612 1.00 41.10 C ANISOU 1421 CG LYS E 195 5206 5208 5201 -5 0 4 C ATOM 1422 CD LYS E 195 30.134 6.463 28.986 1.00 40.43 C ANISOU 1422 CD LYS E 195 5119 5119 5123 -1 -3 -4 C ATOM 1423 CE LYS E 195 30.664 7.395 30.062 1.00 40.22 C ATOM 1424 NZ LYS E 195 29.826 7.309 31.289 1.00 40.31 N ANISOU 1424 NZ LYS E 195 5106 5105 5103 0 3 0 N ATOM 1425 N ALA E 196 33.477 7.791 26.194 1.00 36.96 N ANISOU 1425 N ALA E 196 4689 4664 4686 -5 16 5 N ATOM 1426 CA ALA E 196 34.094 9.102 26.131 1.00 34.74 C ANISOU 1426 CA ALA E 196 4402 4412 4385 7 2 6 C ATOM 1427 C ALA E 196 34.312 9.514 24.675 1.00 32.63 C ANISOU 1427 C ALA E 196 4132 4126 4140 4 0 -21 C ATOM 1428 O ALA E 196 34.171 10.681 24.322 1.00 32.59 O ANISOU 1428 O ALA E 196 4136 4143 4101 -12 -16 7 O ATOM 1429 CB ALA E 196 35.408 9.087 26.880 1.00 34.57 C ATOM 1430 N GLU E 197 34.644 8.549 23.829 1.00 30.23 N ANISOU 1430 N GLU E 197 3824 3838 3820 -8 -4 17 N ATOM 1431 CA GLU E 197 34.889 8.832 22.422 1.00 28.37 C ANISOU 1431 CA GLU E 197 3582 3592 3603 5 -10 -3 C ATOM 1432 C GLU E 197 33.618 9.292 21.714 1.00 26.94 C ANISOU 1432 C GLU E 197 3410 3412 3414 -11 10 -4 C ATOM 1433 O GLU E 197 33.653 10.228 20.913 1.00 26.23 O ANISOU 1433 O GLU E 197 3294 3363 3308 11 -19 -31 O ATOM 1434 CB GLU E 197 35.428 7.594 21.723 1.00 28.33 C ANISOU 1434 CB GLU E 197 3587 3588 3587 -2 1 1 C ATOM 1435 CG GLU E 197 35.866 7.840 20.291 1.00 28.17 C ANISOU 1435 CG GLU E 197 3568 3566 3569 -2 0 0 C ATOM 1436 CD GLU E 197 37.009 8.831 20.212 1.00 28.16 C ANISOU 1436 CD GLU E 197 3564 3569 3566 -2 0 -4 C ATOM 1437 OE1 GLU E 197 37.998 8.643 20.945 1.00 28.29 O ANISOU 1437 OE1 GLU E 197 3543 3614 3590 10 0 22 O ATOM 1438 OE2 GLU E 197 36.915 9.801 19.431 1.00 29.03 O ANISOU 1438 OE2 GLU E 197 3680 3673 3674 -1 -2 9 O ATOM 1439 N LEU E 198 32.507 8.618 22.004 1.00 25.43 N ANISOU 1439 N LEU E 198 3228 3221 3210 21 -19 -4 N ATOM 1440 CA LEU E 198 31.223 8.970 21.414 1.00 24.42 C ANISOU 1440 CA LEU E 198 3107 3080 3089 -4 11 -9 C ATOM 1441 C LEU E 198 30.818 10.399 21.794 1.00 23.55 C ANISOU 1441 C LEU E 198 2991 2990 2964 -20 0 -14 C ATOM 1442 O LEU E 198 30.347 11.151 20.945 1.00 22.86 O ANISOU 1442 O LEU E 198 2921 2883 2882 -27 2 -41 O ATOM 1443 CB LEU E 198 30.131 7.966 21.822 1.00 24.35 C ANISOU 1443 CB LEU E 198 3108 3062 3080 -3 7 -10 C ATOM 1444 CG LEU E 198 30.175 6.599 21.122 1.00 23.85 C ANISOU 1444 CG LEU E 198 3018 3032 3010 -1 -3 7 C ATOM 1445 CD1 LEU E 198 29.155 5.650 21.726 1.00 23.76 C ANISOU 1445 CD1 LEU E 198 3024 2997 3006 0 -6 0 C ATOM 1446 CD2 LEU E 198 29.947 6.731 19.623 1.00 23.53 C ANISOU 1446 CD2 LEU E 198 2970 2972 2996 5 -4 -8 C ATOM 1447 N GLN E 199 31.018 10.791 23.053 1.00 23.00 N ANISOU 1447 N GLN E 199 2913 2915 2910 -11 17 3 N ATOM 1448 CA GLN E 199 30.599 12.140 23.465 1.00 22.62 C ANISOU 1448 CA GLN E 199 2886 2850 2857 -24 15 -7 C ATOM 1449 C GLN E 199 31.673 13.197 23.247 1.00 21.33 C ANISOU 1449 C GLN E 199 2707 2705 2692 8 21 -22 C ATOM 1450 O GLN E 199 31.376 14.379 23.291 1.00 21.91 O ANISOU 1450 O GLN E 199 2790 2724 2809 4 65 14 O ATOM 1451 CB GLN E 199 30.026 12.184 24.882 1.00 23.23 C ANISOU 1451 CB GLN E 199 2974 2940 2911 -24 24 -3 C ATOM 1452 CG GLN E 199 29.666 13.597 25.374 1.00 24.67 C ANISOU 1452 CG GLN E 199 3186 3049 3136 -21 37 -21 C ATOM 1453 CD GLN E 199 28.306 14.087 24.929 1.00 26.40 C ANISOU 1453 CD GLN E 199 3316 3351 3361 30 -21 10 C ATOM 1454 OE1 GLN E 199 28.211 15.116 24.264 1.00 27.40 O ANISOU 1454 OE1 GLN E 199 3564 3432 3413 -30 35 45 O ATOM 1455 NE2 GLN E 199 27.247 13.383 25.330 1.00 27.86 N ANISOU 1455 NE2 GLN E 199 3520 3475 3588 -53 35 7 N ATOM 1456 N SER E 200 32.893 12.784 22.933 1.00 19.87 N ANISOU 1456 N SER E 200 2569 2499 2483 -35 0 -8 N ATOM 1457 CA SER E 200 33.884 13.745 22.483 1.00 18.68 C ANISOU 1457 CA SER E 200 2398 2371 2327 -4 -7 -6 C ATOM 1458 C SER E 200 33.442 14.189 21.081 1.00 17.42 C ANISOU 1458 C SER E 200 2239 2189 2190 -23 10 -29 C ATOM 1459 O SER E 200 33.335 15.377 20.786 1.00 16.73 O ANISOU 1459 O SER E 200 2177 2137 2042 -48 17 -62 O ATOM 1460 CB SER E 200 35.265 13.117 22.410 1.00 18.78 C ANISOU 1460 CB SER E 200 2395 2379 2358 -15 -6 -5 C ATOM 1461 OG SER E 200 36.223 14.085 22.033 1.00 19.58 O ANISOU 1461 OG SER E 200 2547 2413 2478 -28 48 8 O ATOM 1462 N GLU E 201 33.137 13.205 20.236 1.00 16.30 N ANISOU 1462 N GLU E 201 2087 2067 2039 -11 -1 1 N ATOM 1463 CA GLU E 201 32.737 13.456 18.857 1.00 15.57 C ANISOU 1463 CA GLU E 201 1970 1965 1981 -6 -4 -13 C ATOM 1464 C GLU E 201 31.387 14.173 18.787 1.00 15.45 C ANISOU 1464 C GLU E 201 1986 1936 1947 -6 -13 -20 C ATOM 1465 O GLU E 201 31.183 15.037 17.938 1.00 14.70 O ANISOU 1465 O GLU E 201 1890 1828 1865 -12 -13 -50 O ATOM 1466 CB GLU E 201 32.689 12.134 18.074 1.00 15.32 C ANISOU 1466 CB GLU E 201 1935 1949 1935 -1 -5 -14 C ATOM 1467 CG GLU E 201 34.052 11.480 17.868 1.00 15.22 C ANISOU 1467 CG GLU E 201 1941 1924 1917 -6 -18 9 C ATOM 1468 CD GLU E 201 33.996 10.169 17.096 1.00 14.98 C ANISOU 1468 CD GLU E 201 1910 1895 1885 2 5 15 C ATOM 1469 OE1 GLU E 201 32.897 9.760 16.669 1.00 15.15 O ANISOU 1469 OE1 GLU E 201 1997 1860 1899 -5 -32 -16 O ATOM 1470 OE2 GLU E 201 35.060 9.537 16.927 1.00 15.51 O ANISOU 1470 OE2 GLU E 201 2015 1973 1903 5 26 52 O ATOM 1471 N GLU E 202 30.477 13.814 19.689 1.00 15.57 N ANISOU 1471 N GLU E 202 2007 1948 1959 -16 -3 -16 N ATOM 1472 CA GLU E 202 29.153 14.410 19.729 1.00 16.15 C ANISOU 1472 CA GLU E 202 2072 2036 2029 -8 -4 -16 C ATOM 1473 C GLU E 202 29.217 15.870 20.161 1.00 16.54 C ANISOU 1473 C GLU E 202 2129 2075 2078 0 12 -1 C ATOM 1474 O GLU E 202 28.634 16.747 19.524 1.00 15.92 O ANISOU 1474 O GLU E 202 2086 2013 1948 7 21 -39 O ATOM 1475 CB GLU E 202 28.259 13.626 20.692 1.00 16.57 C ANISOU 1475 CB GLU E 202 2153 2077 2064 -28 19 -5 C ATOM 1476 CG GLU E 202 26.941 14.305 21.033 1.00 17.82 C ANISOU 1476 CG GLU E 202 2262 2211 2298 26 35 23 C ATOM 1477 CD GLU E 202 25.930 14.253 19.911 1.00 19.60 C ANISOU 1477 CD GLU E 202 2506 2463 2475 -16 -26 29 C ATOM 1478 OE1 GLU E 202 26.323 13.981 18.761 1.00 21.47 O ANISOU 1478 OE1 GLU E 202 2786 2735 2636 29 56 -15 O ATOM 1479 OE2 GLU E 202 24.729 14.482 20.174 1.00 21.13 O ANISOU 1479 OE2 GLU E 202 2637 2725 2665 34 27 33 O ATOM 1480 N ARG E 203 29.920 16.128 21.254 1.00 17.01 N ANISOU 1480 N ARG E 203 2200 2153 2110 1 -7 -10 N ATOM 1481 CA ARG E 203 30.027 17.489 21.751 1.00 17.83 C ANISOU 1481 CA ARG E 203 2300 2222 2249 -8 10 0 C ATOM 1482 C ARG E 203 30.678 18.349 20.680 1.00 17.39 C ANISOU 1482 C ARG E 203 2235 2183 2187 15 5 -5 C ATOM 1483 O ARG E 203 30.178 19.429 20.357 1.00 17.56 O ANISOU 1483 O ARG E 203 2329 2167 2176 4 -23 0 O ATOM 1484 CB ARG E 203 30.825 17.541 23.056 1.00 18.67 C ANISOU 1484 CB ARG E 203 2397 2344 2350 -8 -15 13 C ATOM 1485 CG ARG E 203 30.199 18.460 24.122 1.00 21.08 C ANISOU 1485 CG ARG E 203 2705 2615 2688 43 69 -46 C ATOM 1486 CD ARG E 203 30.699 18.178 25.537 1.00 23.81 C ANISOU 1486 CD ARG E 203 3079 3023 2944 3 -34 18 C ATOM 1487 NE ARG E 203 29.920 18.845 26.580 1.00 26.17 N ANISOU 1487 NE ARG E 203 3342 3277 3321 35 75 -53 N ATOM 1488 CZ ARG E 203 30.116 18.659 27.879 1.00 27.99 C ANISOU 1488 CZ ARG E 203 3577 3578 3477 4 -10 18 C ATOM 1489 NH1 ARG E 203 31.067 17.832 28.298 1.00 28.85 N ANISOU 1489 NH1 ARG E 203 3659 3649 3654 54 34 24 N ATOM 1490 NH2 ARG E 203 29.373 19.306 28.772 1.00 29.25 N ANISOU 1490 NH2 ARG E 203 3695 3696 3723 58 50 7 N ATOM 1491 N LYS E 204 31.774 17.851 20.110 1.00 16.67 N ANISOU 1491 N LYS E 204 2154 2080 2098 -10 3 5 N ATOM 1492 CA LYS E 204 32.484 18.575 19.063 1.00 16.20 C ANISOU 1492 CA LYS E 204 2066 2028 2059 0 4 -4 C ATOM 1493 C LYS E 204 31.561 18.852 17.884 1.00 15.44 C ANISOU 1493 C LYS E 204 1944 1930 1992 -16 10 2 C ATOM 1494 O LYS E 204 31.613 19.919 17.287 1.00 15.27 O ANISOU 1494 O LYS E 204 1873 1916 2013 -19 39 7 O ATOM 1495 CB LYS E 204 33.730 17.809 18.599 1.00 16.27 C ANISOU 1495 CB LYS E 204 2053 2039 2090 1 14 10 C ATOM 1496 CG LYS E 204 34.871 17.861 19.595 1.00 17.41 C ANISOU 1496 CG LYS E 204 2231 2182 2201 -8 0 13 C ATOM 1497 CD LYS E 204 36.194 17.435 18.984 1.00 18.20 C ANISOU 1497 CD LYS E 204 2293 2300 2320 1 20 1 C ATOM 1498 CE LYS E 204 37.367 17.820 19.872 1.00 18.73 C ANISOU 1498 CE LYS E 204 2375 2364 2377 -5 -19 12 C ATOM 1499 NZ LYS E 204 38.653 17.330 19.330 1.00 19.61 N ANISOU 1499 NZ LYS E 204 2515 2454 2482 27 65 16 N ATOM 1500 N ARG E 205 30.693 17.897 17.570 1.00 14.71 N ANISOU 1500 N ARG E 205 1873 1815 1899 12 3 7 N ATOM 1501 CA ARG E 205 29.786 18.033 16.442 1.00 14.02 C ANISOU 1501 CA ARG E 205 1762 1759 1805 -5 19 -3 C ATOM 1502 C ARG E 205 28.769 19.151 16.677 1.00 13.44 C ANISOU 1502 C ARG E 205 1696 1677 1730 -26 -13 3 C ATOM 1503 O ARG E 205 28.542 19.981 15.803 1.00 12.76 O ANISOU 1503 O ARG E 205 1584 1589 1674 -39 19 20 O ATOM 1504 CB ARG E 205 29.078 16.700 16.187 1.00 14.31 C ANISOU 1504 CB ARG E 205 1804 1778 1854 0 6 -1 C ATOM 1505 CG ARG E 205 28.265 16.643 14.925 1.00 15.05 C ANISOU 1505 CG ARG E 205 1946 1861 1912 -1 17 22 C ATOM 1506 CD ARG E 205 27.901 15.232 14.508 1.00 15.32 C ANISOU 1506 CD ARG E 205 2029 1920 1870 -53 -6 -3 C ATOM 1507 NE ARG E 205 27.692 14.320 15.636 1.00 14.94 N ANISOU 1507 NE ARG E 205 1991 1824 1860 -47 -31 -10 N ATOM 1508 CZ ARG E 205 28.448 13.264 15.920 1.00 13.49 C ANISOU 1508 CZ ARG E 205 1670 1738 1714 -75 -18 -20 C ATOM 1509 NH1 ARG E 205 29.515 12.960 15.192 1.00 14.47 N ANISOU 1509 NH1 ARG E 205 1879 1812 1805 -20 47 -15 N ATOM 1510 NH2 ARG E 205 28.146 12.508 16.963 1.00 12.92 N ANISOU 1510 NH2 ARG E 205 1690 1630 1587 -58 -14 -59 N ATOM 1511 N ILE E 206 28.155 19.156 17.856 1.00 13.01 N ANISOU 1511 N ILE E 206 1630 1643 1670 -14 -13 -6 N ATOM 1512 CA ILE E 206 27.172 20.180 18.205 1.00 13.44 C ANISOU 1512 CA ILE E 206 1721 1659 1723 -8 17 0 C ATOM 1513 C ILE E 206 27.839 21.543 18.387 1.00 13.78 C ANISOU 1513 C ILE E 206 1750 1705 1779 -22 -7 -3 C ATOM 1514 O ILE E 206 27.314 22.560 17.930 1.00 13.45 O ANISOU 1514 O ILE E 206 1687 1586 1836 -91 0 -5 O ATOM 1515 CB ILE E 206 26.424 19.799 19.501 1.00 13.56 C ANISOU 1515 CB ILE E 206 1730 1689 1730 15 24 14 C ATOM 1516 CG1 ILE E 206 25.559 18.578 19.275 1.00 14.09 C ANISOU 1516 CG1 ILE E 206 1860 1699 1794 -7 43 -18 C ATOM 1517 CG2 ILE E 206 25.553 20.949 19.999 1.00 13.10 C ANISOU 1517 CG2 ILE E 206 1655 1600 1722 -27 46 19 C ATOM 1518 CD1 ILE E 206 25.063 17.951 20.554 1.00 14.63 C ANISOU 1518 CD1 ILE E 206 2021 1799 1738 -15 13 -64 C ATOM 1519 N ASP E 207 28.977 21.565 19.072 1.00 14.37 N ANISOU 1519 N ASP E 207 1808 1779 1872 -16 7 0 N ATOM 1520 CA ASP E 207 29.696 22.818 19.299 1.00 14.95 C ANISOU 1520 CA ASP E 207 1906 1853 1921 -9 8 -4 C ATOM 1521 C ASP E 207 30.038 23.453 17.940 1.00 14.88 C ANISOU 1521 C ASP E 207 1904 1835 1914 0 16 -1 C ATOM 1522 O ASP E 207 29.867 24.656 17.738 1.00 15.10 O ANISOU 1522 O ASP E 207 1914 1852 1972 16 58 41 O ATOM 1523 CB ASP E 207 30.958 22.585 20.145 1.00 15.46 C ANISOU 1523 CB ASP E 207 1992 1898 1983 15 -4 -10 C ATOM 1524 CG ASP E 207 30.641 22.189 21.597 1.00 16.96 C ANISOU 1524 CG ASP E 207 2230 2094 2117 12 28 -5 C ATOM 1525 OD1 ASP E 207 29.446 21.984 21.928 1.00 18.38 O ANISOU 1525 OD1 ASP E 207 2390 2229 2364 -8 68 -27 O ATOM 1526 OD2 ASP E 207 31.545 22.056 22.467 1.00 19.04 O ANISOU 1526 OD2 ASP E 207 2491 2407 2336 24 -24 34 O ATOM 1527 N GLU E 208 30.507 22.632 17.007 1.00 14.41 N ANISOU 1527 N GLU E 208 1816 1798 1858 -26 24 4 N ATOM 1528 CA GLU E 208 30.847 23.100 15.677 1.00 14.62 C ANISOU 1528 CA GLU E 208 1869 1820 1863 -19 -5 14 C ATOM 1529 C GLU E 208 29.643 23.720 14.992 1.00 13.67 C ANISOU 1529 C GLU E 208 1709 1699 1783 -41 27 12 C ATOM 1530 O GLU E 208 29.752 24.729 14.326 1.00 13.57 O ANISOU 1530 O GLU E 208 1714 1650 1790 -83 68 18 O ATOM 1531 CB GLU E 208 31.343 21.944 14.823 1.00 15.14 C ANISOU 1531 CB GLU E 208 1953 1894 1904 -29 20 -2 C ATOM 1532 CG GLU E 208 32.765 21.516 15.087 1.00 17.33 C ANISOU 1532 CG GLU E 208 2186 2207 2191 7 -41 56 C ATOM 1533 CD GLU E 208 33.263 20.554 14.030 1.00 20.11 C ANISOU 1533 CD GLU E 208 2633 2504 2503 59 9 -23 C ATOM 1534 OE1 GLU E 208 32.583 19.534 13.801 1.00 22.96 O ANISOU 1534 OE1 GLU E 208 3017 2754 2952 -56 -26 17 O ATOM 1535 OE2 GLU E 208 34.321 20.812 13.423 1.00 21.55 O ANISOU 1535 OE2 GLU E 208 2697 2732 2757 50 39 48 O ATOM 1536 N LEU E 209 28.482 23.096 15.128 1.00 12.94 N ANISOU 1536 N LEU E 209 1627 1615 1671 -38 9 -1 N ATOM 1537 CA LEU E 209 27.297 23.618 14.477 1.00 12.96 C ANISOU 1537 CA LEU E 209 1648 1613 1662 -8 28 0 C ATOM 1538 C LEU E 209 26.829 24.906 15.133 1.00 12.93 C ANISOU 1538 C LEU E 209 1620 1594 1698 -45 6 10 C ATOM 1539 O LEU E 209 26.340 25.796 14.459 1.00 13.66 O ANISOU 1539 O LEU E 209 1738 1596 1856 -40 -6 42 O ATOM 1540 CB LEU E 209 26.185 22.576 14.500 1.00 12.78 C ANISOU 1540 CB LEU E 209 1613 1640 1602 -19 -7 -3 C ATOM 1541 CG LEU E 209 26.480 21.389 13.588 1.00 14.22 C ANISOU 1541 CG LEU E 209 1823 1742 1836 0 47 -7 C ATOM 1542 CD1 LEU E 209 25.614 20.166 13.909 1.00 14.77 C ANISOU 1542 CD1 LEU E 209 1829 1799 1984 -40 18 5 C ATOM 1543 CD2 LEU E 209 26.273 21.808 12.151 1.00 15.60 C ANISOU 1543 CD2 LEU E 209 2081 1921 1926 12 -60 -11 C ATOM 1544 N ILE E 210 26.935 24.992 16.446 1.00 13.19 N ANISOU 1544 N ILE E 210 1636 1646 1728 -20 -4 4 N ATOM 1545 CA ILE E 210 26.526 26.218 17.136 1.00 13.66 C ANISOU 1545 CA ILE E 210 1734 1690 1763 5 11 3 C ATOM 1546 C ILE E 210 27.438 27.370 16.723 1.00 14.26 C ANISOU 1546 C ILE E 210 1829 1749 1839 6 7 19 C ATOM 1547 O ILE E 210 26.946 28.442 16.375 1.00 14.95 O ANISOU 1547 O ILE E 210 2020 1768 1893 53 58 49 O ATOM 1548 CB ILE E 210 26.516 26.037 18.661 1.00 13.28 C ANISOU 1548 CB ILE E 210 1662 1667 1715 -10 -6 -37 C ATOM 1549 CG1 ILE E 210 25.381 25.098 19.070 1.00 13.27 C ANISOU 1549 CG1 ILE E 210 1741 1649 1652 -2 24 -7 C ATOM 1550 CG2 ILE E 210 26.349 27.391 19.362 1.00 14.16 C ANISOU 1550 CG2 ILE E 210 1832 1733 1816 34 54 -11 C ATOM 1551 CD1 ILE E 210 25.505 24.532 20.443 1.00 12.99 C ANISOU 1551 CD1 ILE E 210 1686 1619 1628 -16 -35 -37 C ATOM 1552 N GLU E 211 28.750 27.123 16.736 1.00 14.38 N ANISOU 1552 N GLU E 211 1819 1788 1857 -8 23 16 N ATOM 1553 CA GLU E 211 29.764 28.138 16.419 1.00 14.59 C ANISOU 1553 CA GLU E 211 1832 1828 1883 -10 0 -3 C ATOM 1554 C GLU E 211 29.693 28.635 14.990 1.00 14.49 C ANISOU 1554 C GLU E 211 1816 1804 1885 -11 4 2 C ATOM 1555 O GLU E 211 29.945 29.809 14.728 1.00 15.27 O ANISOU 1555 O GLU E 211 2016 1822 1964 25 -79 -10 O ATOM 1556 CB GLU E 211 31.172 27.584 16.689 1.00 15.05 C ANISOU 1556 CB GLU E 211 1864 1887 1964 -20 6 -3 C ATOM 1557 CG GLU E 211 31.428 27.318 18.165 1.00 17.14 C ANISOU 1557 CG GLU E 211 2215 2193 2101 -47 13 1 C ATOM 1558 CD GLU E 211 32.578 26.364 18.434 1.00 20.82 C ANISOU 1558 CD GLU E 211 2662 2560 2687 78 -34 32 C ATOM 1559 OE1 GLU E 211 33.144 25.771 17.482 1.00 23.26 O ANISOU 1559 OE1 GLU E 211 3083 2894 2859 76 68 -20 O ATOM 1560 OE2 GLU E 211 32.917 26.203 19.624 1.00 23.81 O ANISOU 1560 OE2 GLU E 211 3224 2945 2879 2 -129 17 O ATOM 1561 N SER E 212 29.387 27.738 14.061 1.00 14.13 N ANISOU 1561 N SER E 212 1750 1773 1844 -29 -2 7 N ATOM 1562 CA SER E 212 29.362 28.082 12.652 1.00 14.43 C ANISOU 1562 CA SER E 212 1817 1801 1863 -26 -15 2 C ATOM 1563 C SER E 212 28.045 28.700 12.231 1.00 14.43 C ANISOU 1563 C SER E 212 1814 1802 1863 -16 -9 0 C ATOM 1564 O SER E 212 27.972 29.399 11.225 1.00 14.70 O ANISOU 1564 O SER E 212 1890 1796 1898 -18 -92 0 O ATOM 1565 CB SER E 212 29.625 26.841 11.793 1.00 14.60 C ANISOU 1565 CB SER E 212 1843 1807 1894 8 -2 6 C ATOM 1566 OG SER E 212 28.607 25.872 11.967 1.00 15.21 O ANISOU 1566 OG SER E 212 1904 1824 2049 14 -31 -15 O ATOM 1567 N GLY E 213 26.998 28.416 12.989 1.00 14.86 N ANISOU 1567 N GLY E 213 1878 1872 1895 -31 -9 2 N ATOM 1568 CA GLY E 213 25.672 28.870 12.626 1.00 15.32 C ANISOU 1568 CA GLY E 213 1913 1939 1967 13 -7 1 C ATOM 1569 C GLY E 213 25.140 28.188 11.366 1.00 15.78 C ANISOU 1569 C GLY E 213 1984 1991 2020 11 -18 -3 C ATOM 1570 O GLY E 213 24.203 28.676 10.749 1.00 15.90 O ANISOU 1570 O GLY E 213 1976 1988 2077 -11 -117 -3 O ATOM 1571 N LYS E 214 25.755 27.082 10.951 1.00 16.18 N ANISOU 1571 N LYS E 214 2063 2011 2072 14 -22 -3 N ATOM 1572 CA LYS E 214 25.294 26.381 9.766 1.00 16.20 C ANISOU 1572 CA LYS E 214 2025 2061 2068 -6 -7 0 C ATOM 1573 C LYS E 214 23.876 25.837 10.021 1.00 15.92 C ANISOU 1573 C LYS E 214 2001 2012 2036 -20 -16 5 C ATOM 1574 O LYS E 214 23.631 25.150 11.011 1.00 15.34 O ANISOU 1574 O LYS E 214 1784 1975 2067 -39 6 -6 O ATOM 1575 CB LYS E 214 26.289 25.285 9.364 1.00 16.71 C ANISOU 1575 CB LYS E 214 2124 2095 2130 13 -37 -4 C ATOM 1576 CG LYS E 214 27.591 25.823 8.732 1.00 18.59 C ANISOU 1576 CG LYS E 214 2351 2330 2379 1 -5 -14 C ATOM 1577 CD LYS E 214 27.355 26.426 7.339 1.00 20.32 C ANISOU 1577 CD LYS E 214 2634 2555 2531 37 -21 13 C ATOM 1578 CE LYS E 214 28.607 27.028 6.739 1.00 21.70 C ANISOU 1578 CE LYS E 214 2793 2708 2742 -1 19 11 C ATOM 1579 NZ LYS E 214 28.342 27.589 5.375 1.00 22.72 N ANISOU 1579 NZ LYS E 214 2978 2808 2843 28 -55 18 N ATOM 1580 N GLU E 215 22.941 26.215 9.159 1.00 15.89 N ANISOU 1580 N GLU E 215 1985 2026 2027 -3 2 25 N ATOM 1581 CA GLU E 215 21.545 25.783 9.277 1.00 16.20 C ANISOU 1581 CA GLU E 215 2026 2055 2072 1 -19 0 C ATOM 1582 C GLU E 215 21.070 25.101 7.986 1.00 16.59 C ANISOU 1582 C GLU E 215 2094 2083 2123 37 -49 -16 C ATOM 1583 O GLU E 215 20.212 25.621 7.271 1.00 17.82 O ANISOU 1583 O GLU E 215 2319 2219 2229 113 -122 -19 O ATOM 1584 CB GLU E 215 20.651 26.973 9.662 1.00 16.02 C ANISOU 1584 CB GLU E 215 1996 2024 2064 -6 4 6 C ATOM 1585 CG GLU E 215 21.085 27.604 10.987 1.00 16.38 C ANISOU 1585 CG GLU E 215 2052 2132 2040 34 41 0 C ATOM 1586 CD GLU E 215 20.186 28.718 11.520 1.00 16.87 C ANISOU 1586 CD GLU E 215 2126 2191 2092 71 -21 -39 C ATOM 1587 OE1 GLU E 215 19.359 29.275 10.753 1.00 16.74 O ANISOU 1587 OE1 GLU E 215 2061 2194 2104 90 -16 -59 O ATOM 1588 OE2 GLU E 215 20.341 29.046 12.727 1.00 16.35 O ANISOU 1588 OE2 GLU E 215 1971 2221 2018 79 160 34 O ATOM 1589 N GLU E 216 21.616 23.916 7.715 1.00 16.18 N ANISOU 1589 N GLU E 216 1998 2068 2079 29 -50 -25 N ATOM 1590 CA GLU E 216 21.311 23.163 6.506 1.00 15.71 C ANISOU 1590 CA GLU E 216 1960 1988 2018 -3 -15 0 C ATOM 1591 C GLU E 216 20.095 22.262 6.658 1.00 14.24 C ANISOU 1591 C GLU E 216 1794 1811 1803 13 -29 -12 C ATOM 1592 O GLU E 216 19.745 21.852 7.765 1.00 14.21 O ANISOU 1592 O GLU E 216 1773 1776 1850 -29 -82 5 O ATOM 1593 CB GLU E 216 22.508 22.293 6.098 1.00 16.48 C ANISOU 1593 CB GLU E 216 2071 2077 2112 38 -50 -24 C ATOM 1594 CG GLU E 216 23.640 23.047 5.431 1.00 19.19 C ANISOU 1594 CG GLU E 216 2416 2424 2451 -36 10 35 C ATOM 1595 CD GLU E 216 24.802 22.136 5.044 1.00 22.06 C ANISOU 1595 CD GLU E 216 2730 2768 2882 77 31 -23 C ATOM 1596 OE1 GLU E 216 25.385 21.485 5.942 1.00 23.99 O ANISOU 1596 OE1 GLU E 216 2975 3053 3085 85 -68 48 O ATOM 1597 OE2 GLU E 216 25.133 22.061 3.847 1.00 24.36 O ANISOU 1597 OE2 GLU E 216 3126 3082 3045 25 21 20 O ATOM 1598 N GLY E 217 19.452 21.967 5.530 1.00 12.87 N ANISOU 1598 N GLY E 217 1604 1628 1655 -8 -6 1 N ATOM 1599 CA GLY E 217 18.350 21.025 5.502 1.00 11.56 C ANISOU 1599 CA GLY E 217 1432 1487 1470 3 -1 18 C ATOM 1600 C GLY E 217 16.998 21.595 5.860 1.00 10.91 C ANISOU 1600 C GLY E 217 1344 1397 1403 -23 14 29 C ATOM 1601 O GLY E 217 16.098 20.842 6.225 1.00 10.72 O ANISOU 1601 O GLY E 217 1184 1366 1522 -30 -73 66 O ATOM 1602 N MET E 218 16.851 22.911 5.766 1.00 10.35 N ANISOU 1602 N MET E 218 1212 1351 1368 -5 40 74 N ATOM 1603 CA MET E 218 15.625 23.594 6.165 1.00 10.59 C ANISOU 1603 CA MET E 218 1268 1374 1380 5 28 56 C ATOM 1604 C MET E 218 15.312 24.725 5.216 1.00 10.40 C ANISOU 1604 C MET E 218 1235 1344 1369 18 48 79 C ATOM 1605 O MET E 218 16.199 25.327 4.621 1.00 10.62 O ANISOU 1605 O MET E 218 1083 1397 1552 3 9 85 O ATOM 1606 CB MET E 218 15.772 24.190 7.556 1.00 11.03 C ANISOU 1606 CB MET E 218 1261 1491 1436 62 106 6 C ATOM 1607 CG MET E 218 15.937 23.184 8.654 1.00 13.81 C ANISOU 1607 CG MET E 218 1639 1713 1895 78 42 87 C ATOM 1608 SD MET E 218 16.346 24.003 10.181 1.00 16.74 S ANISOU 1608 SD MET E 218 1880 2496 1982 130 -178 88 S ATOM 1609 CE MET E 218 18.025 24.402 9.879 1.00 17.30 C ANISOU 1609 CE MET E 218 2006 2284 2282 35 -64 34 C ATOM 1610 N LYS E 219 14.028 25.008 5.089 1.00 10.55 N ANISOU 1610 N LYS E 219 1250 1352 1405 -25 49 73 N ATOM 1611 CA LYS E 219 13.539 26.079 4.259 1.00 11.15 C ANISOU 1611 CA LYS E 219 1329 1430 1475 5 21 38 C ATOM 1612 C LYS E 219 12.310 26.696 4.931 1.00 10.10 C ANISOU 1612 C LYS E 219 1269 1329 1240 7 21 46 C ATOM 1613 O LYS E 219 11.601 26.025 5.668 1.00 9.30 O ANISOU 1613 O LYS E 219 1158 1202 1171 5 -8 22 O ATOM 1614 CB LYS E 219 13.212 25.518 2.877 1.00 12.05 C ANISOU 1614 CB LYS E 219 1523 1536 1516 35 44 43 C ATOM 1615 CG LYS E 219 11.875 25.887 2.309 1.00 15.05 C ANISOU 1615 CG LYS E 219 1769 1960 1989 21 -58 -11 C ATOM 1616 CD LYS E 219 11.816 25.440 0.856 1.00 19.06 C ANISOU 1616 CD LYS E 219 2498 2489 2254 15 -18 -88 C ATOM 1617 CE LYS E 219 11.074 26.439 -0.043 1.00 22.11 C ANISOU 1617 CE LYS E 219 2808 2718 2874 40 -87 69 C ATOM 1618 NZ LYS E 219 11.140 26.072 -1.493 1.00 24.04 N ANISOU 1618 NZ LYS E 219 3069 3042 3021 8 -20 -4 N ATOM 1619 N ILE E 220 12.066 27.974 4.671 1.00 10.34 N ANISOU 1619 N ILE E 220 1260 1324 1344 -17 13 -12 N ATOM 1620 CA ILE E 220 10.873 28.651 5.166 1.00 10.33 C ANISOU 1620 CA ILE E 220 1292 1372 1259 0 20 17 C ATOM 1621 C ILE E 220 9.744 28.492 4.152 1.00 10.40 C ANISOU 1621 C ILE E 220 1270 1364 1318 -4 18 39 C ATOM 1622 O ILE E 220 9.975 28.552 2.938 1.00 9.67 O ANISOU 1622 O ILE E 220 1028 1394 1251 50 37 3 O ATOM 1623 CB ILE E 220 11.159 30.141 5.356 1.00 10.69 C ANISOU 1623 CB ILE E 220 1393 1381 1284 27 32 29 C ATOM 1624 CG1 ILE E 220 12.321 30.337 6.331 1.00 12.86 C ANISOU 1624 CG1 ILE E 220 1601 1650 1634 12 -33 -18 C ATOM 1625 CG2 ILE E 220 9.903 30.876 5.827 1.00 11.90 C ANISOU 1625 CG2 ILE E 220 1474 1472 1575 2 39 -33 C ATOM 1626 CD1 ILE E 220 12.925 31.685 6.270 1.00 15.53 C ANISOU 1626 CD1 ILE E 220 1974 1861 2064 -58 -14 -16 C ATOM 1627 N ASP E 221 8.524 28.323 4.661 1.00 10.48 N ANISOU 1627 N ASP E 221 1251 1411 1318 16 64 47 N ATOM 1628 CA ASP E 221 7.334 28.243 3.821 1.00 11.94 C ANISOU 1628 CA ASP E 221 1463 1556 1516 10 11 23 C ATOM 1629 C ASP E 221 6.155 28.863 4.577 1.00 11.06 C ANISOU 1629 C ASP E 221 1392 1434 1374 9 5 21 C ATOM 1630 O ASP E 221 6.243 29.082 5.778 1.00 11.47 O ANISOU 1630 O ASP E 221 1409 1504 1444 51 10 22 O ATOM 1631 CB ASP E 221 7.053 26.778 3.476 1.00 13.08 C ANISOU 1631 CB ASP E 221 1630 1652 1686 10 60 -14 C ATOM 1632 CG ASP E 221 5.941 26.600 2.467 1.00 17.34 C ANISOU 1632 CG ASP E 221 2108 2293 2188 -5 -64 -27 C ATOM 1633 OD1 ASP E 221 5.636 27.534 1.675 1.00 20.64 O ANISOU 1633 OD1 ASP E 221 2622 2556 2662 63 -4 65 O ATOM 1634 OD2 ASP E 221 5.312 25.520 2.386 1.00 22.23 O ANISOU 1634 OD2 ASP E 221 2723 2593 3130 -143 -50 -36 O ATOM 1635 N LEU E 222 5.064 29.171 3.869 1.00 10.67 N ANISOU 1635 N LEU E 222 1296 1398 1357 7 29 31 N ATOM 1636 CA LEU E 222 3.839 29.656 4.515 1.00 10.52 C ANISOU 1636 CA LEU E 222 1316 1329 1352 15 7 9 C ATOM 1637 C LEU E 222 3.024 28.412 4.863 1.00 9.88 C ANISOU 1637 C LEU E 222 1162 1300 1290 30 9 -4 C ATOM 1638 O LEU E 222 2.805 27.557 4.015 1.00 10.44 O ANISOU 1638 O LEU E 222 1213 1301 1450 -28 57 -17 O ATOM 1639 CB LEU E 222 3.046 30.601 3.603 1.00 10.51 C ANISOU 1639 CB LEU E 222 1310 1318 1362 16 -3 28 C ATOM 1640 CG LEU E 222 3.725 31.943 3.283 1.00 11.54 C ANISOU 1640 CG LEU E 222 1417 1489 1478 -25 19 91 C ATOM 1641 CD1 LEU E 222 2.872 32.772 2.312 1.00 12.48 C ANISOU 1641 CD1 LEU E 222 1537 1563 1640 37 17 53 C ATOM 1642 CD2 LEU E 222 4.008 32.723 4.532 1.00 13.07 C ANISOU 1642 CD2 LEU E 222 1630 1565 1772 -5 27 36 C ATOM 1643 N ILE E 223 2.615 28.300 6.120 1.00 9.41 N ANISOU 1643 N ILE E 223 1155 1203 1214 11 -3 6 N ATOM 1644 CA ILE E 223 1.863 27.139 6.591 1.00 9.62 C ANISOU 1644 CA ILE E 223 1191 1216 1245 3 47 -10 C ATOM 1645 C ILE E 223 0.461 27.601 6.979 1.00 7.77 C ANISOU 1645 C ILE E 223 1013 953 983 -21 41 -24 C ATOM 1646 O ILE E 223 0.321 28.583 7.714 1.00 7.05 O ANISOU 1646 O ILE E 223 927 763 988 -56 203 -21 O ATOM 1647 CB ILE E 223 2.585 26.491 7.778 1.00 11.31 C ANISOU 1647 CB ILE E 223 1434 1410 1451 31 51 31 C ATOM 1648 CG1 ILE E 223 4.003 26.078 7.357 1.00 14.17 C ANISOU 1648 CG1 ILE E 223 1693 1755 1935 46 71 34 C ATOM 1649 CG2 ILE E 223 1.807 25.298 8.262 1.00 12.24 C ANISOU 1649 CG2 ILE E 223 1514 1529 1608 43 128 89 C ATOM 1650 CD1 ILE E 223 4.878 25.806 8.456 1.00 17.60 C ANISOU 1650 CD1 ILE E 223 2145 2285 2256 -4 0 32 C ATOM 1651 N ASP E 224 -0.560 26.909 6.481 1.00 6.93 N ANISOU 1651 N ASP E 224 929 808 894 4 76 22 N ATOM 1652 CA ASP E 224 -1.961 27.289 6.696 1.00 6.56 C ANISOU 1652 CA ASP E 224 834 790 866 -11 12 23 C ATOM 1653 C ASP E 224 -2.262 27.452 8.179 1.00 6.79 C ANISOU 1653 C ASP E 224 857 847 873 5 23 52 C ATOM 1654 O ASP E 224 -2.054 26.518 8.960 1.00 8.23 O ANISOU 1654 O ASP E 224 1068 923 1135 37 150 181 O ATOM 1655 CB ASP E 224 -2.873 26.212 6.093 1.00 6.58 C ANISOU 1655 CB ASP E 224 874 742 883 -48 16 41 C ATOM 1656 CG ASP E 224 -4.325 26.630 5.973 1.00 7.31 C ANISOU 1656 CG ASP E 224 932 798 1045 -23 81 -80 C ATOM 1657 OD1 ASP E 224 -4.668 27.802 6.229 1.00 8.61 O ANISOU 1657 OD1 ASP E 224 1118 711 1441 -75 228 27 O ATOM 1658 OD2 ASP E 224 -5.213 25.845 5.548 1.00 7.12 O ANISOU 1658 OD2 ASP E 224 799 615 1290 -135 137 -36 O ATOM 1659 N GLY E 225 -2.709 28.644 8.580 1.00 6.75 N ANISOU 1659 N GLY E 225 856 836 873 -31 61 54 N ATOM 1660 CA GLY E 225 -3.045 28.920 9.970 1.00 7.39 C ANISOU 1660 CA GLY E 225 961 905 938 -41 51 -1 C ATOM 1661 C GLY E 225 -1.907 29.210 10.938 1.00 7.94 C ANISOU 1661 C GLY E 225 1042 988 987 3 30 -5 C ATOM 1662 O GLY E 225 -2.153 29.375 12.135 1.00 9.66 O ANISOU 1662 O GLY E 225 1274 1284 1110 -18 91 18 O ATOM 1663 N LYS E 226 -0.667 29.294 10.462 1.00 7.91 N ANISOU 1663 N LYS E 226 1028 981 996 10 68 28 N ATOM 1664 CA LYS E 226 0.456 29.511 11.373 1.00 8.36 C ANISOU 1664 CA LYS E 226 1046 1036 1094 26 43 12 C ATOM 1665 C LYS E 226 1.375 30.665 10.962 1.00 8.38 C ANISOU 1665 C LYS E 226 1068 1042 1074 0 16 14 C ATOM 1666 O LYS E 226 2.198 31.120 11.761 1.00 10.89 O ANISOU 1666 O LYS E 226 1386 1387 1363 -32 -17 74 O ATOM 1667 CB LYS E 226 1.295 28.232 11.530 1.00 8.46 C ANISOU 1667 CB LYS E 226 1085 1025 1102 36 52 20 C ATOM 1668 CG LYS E 226 0.518 26.995 11.931 1.00 9.65 C ANISOU 1668 CG LYS E 226 1177 1232 1257 -18 63 23 C ATOM 1669 CD LYS E 226 1.432 25.842 12.262 1.00 12.12 C ANISOU 1669 CD LYS E 226 1563 1525 1515 92 16 7 C ATOM 1670 CE LYS E 226 0.684 24.515 12.283 1.00 14.62 C ANISOU 1670 CE LYS E 226 1843 1744 1966 15 19 40 C ATOM 1671 NZ LYS E 226 1.616 23.347 12.187 1.00 16.21 N ANISOU 1671 NZ LYS E 226 2167 1844 2148 162 101 -22 N ATOM 1672 N GLY E 227 1.222 31.159 9.737 1.00 7.98 N ANISOU 1672 N GLY E 227 1004 976 1052 7 25 3 N ATOM 1673 CA GLY E 227 2.134 32.170 9.230 1.00 8.01 C ANISOU 1673 CA GLY E 227 1040 964 1037 28 17 14 C ATOM 1674 C GLY E 227 3.296 31.480 8.562 1.00 7.92 C ANISOU 1674 C GLY E 227 999 1009 997 -26 15 14 C ATOM 1675 O GLY E 227 3.087 30.578 7.750 1.00 8.91 O ANISOU 1675 O GLY E 227 1066 1093 1226 -90 81 -64 O ATOM 1676 N ARG E 228 4.515 31.911 8.865 1.00 7.67 N ANISOU 1676 N ARG E 228 983 930 999 -8 -23 34 N ATOM 1677 CA ARG E 228 5.689 31.240 8.343 1.00 7.58 C ANISOU 1677 CA ARG E 228 984 966 928 -12 7 40 C ATOM 1678 C ARG E 228 5.994 30.026 9.208 1.00 7.72 C ANISOU 1678 C ARG E 228 934 982 1015 27 -29 10 C ATOM 1679 O ARG E 228 5.677 30.003 10.385 1.00 8.52 O ANISOU 1679 O ARG E 228 1072 1010 1153 33 -35 44 O ATOM 1680 CB ARG E 228 6.919 32.138 8.422 1.00 8.37 C ANISOU 1680 CB ARG E 228 1022 1051 1107 -10 -20 0 C ATOM 1681 CG ARG E 228 6.948 33.330 7.493 1.00 9.53 C ANISOU 1681 CG ARG E 228 1205 1208 1207 -7 -15 54 C ATOM 1682 CD ARG E 228 8.037 34.358 7.855 1.00 10.17 C ANISOU 1682 CD ARG E 228 1226 1269 1366 -24 -42 55 C ATOM 1683 NE ARG E 228 7.823 34.964 9.172 1.00 11.09 N ANISOU 1683 NE ARG E 228 1333 1364 1514 -22 -26 0 N ATOM 1684 CZ ARG E 228 8.646 35.851 9.743 1.00 9.30 C ANISOU 1684 CZ ARG E 228 1167 1156 1208 29 -98 83 C ATOM 1685 NH1 ARG E 228 9.751 36.226 9.114 1.00 10.17 N ANISOU 1685 NH1 ARG E 228 1258 1228 1376 16 23 74 N ATOM 1686 NH2 ARG E 228 8.378 36.363 10.936 1.00 11.44 N ANISOU 1686 NH2 ARG E 228 1371 1396 1578 80 104 33 N ATOM 1687 N GLY E 229 6.650 29.043 8.610 1.00 8.10 N ANISOU 1687 N GLY E 229 1019 1014 1043 8 -29 29 N ATOM 1688 CA GLY E 229 7.131 27.899 9.349 1.00 8.03 C ANISOU 1688 CA GLY E 229 981 1015 1053 24 10 42 C ATOM 1689 C GLY E 229 8.371 27.392 8.656 1.00 7.60 C ANISOU 1689 C GLY E 229 940 1001 948 21 24 49 C ATOM 1690 O GLY E 229 8.753 27.895 7.589 1.00 8.44 O ANISOU 1690 O GLY E 229 904 1240 1060 130 -1 166 O ATOM 1691 N VAL E 230 9.006 26.403 9.257 1.00 7.20 N ANISOU 1691 N VAL E 230 920 899 917 -12 7 62 N ATOM 1692 CA VAL E 230 10.235 25.836 8.725 1.00 7.88 C ANISOU 1692 CA VAL E 230 1000 985 1006 -18 32 11 C ATOM 1693 C VAL E 230 9.979 24.370 8.368 1.00 8.30 C ANISOU 1693 C VAL E 230 1031 992 1129 -1 16 64 C ATOM 1694 O VAL E 230 9.448 23.601 9.191 1.00 8.13 O ANISOU 1694 O VAL E 230 1139 926 1023 19 44 79 O ATOM 1695 CB VAL E 230 11.377 25.937 9.702 1.00 8.48 C ANISOU 1695 CB VAL E 230 1033 1053 1135 -6 50 29 C ATOM 1696 CG1 VAL E 230 12.651 25.387 9.066 1.00 9.00 C ANISOU 1696 CG1 VAL E 230 1060 1140 1219 108 -37 -6 C ATOM 1697 CG2 VAL E 230 11.598 27.378 10.103 1.00 9.74 C ANISOU 1697 CG2 VAL E 230 1269 1162 1268 30 -13 -50 C ATOM 1698 N ILE E 231 10.323 24.020 7.132 1.00 8.94 N ANISOU 1698 N ILE E 231 1051 1126 1218 30 -7 27 N ATOM 1699 CA ILE E 231 10.126 22.678 6.601 1.00 9.48 C ANISOU 1699 CA ILE E 231 1162 1186 1251 -9 21 0 C ATOM 1700 C ILE E 231 11.473 22.002 6.375 1.00 8.80 C ANISOU 1700 C ILE E 231 1106 1110 1125 -29 14 -15 C ATOM 1701 O ILE E 231 12.451 22.642 5.946 1.00 9.17 O ANISOU 1701 O ILE E 231 1108 1178 1196 6 11 16 O ATOM 1702 CB ILE E 231 9.275 22.717 5.289 1.00 10.83 C ANISOU 1702 CB ILE E 231 1286 1388 1441 -37 -12 -44 C ATOM 1703 CG1 ILE E 231 7.802 23.034 5.630 1.00 13.63 C ANISOU 1703 CG1 ILE E 231 1551 1747 1881 82 -27 0 C ATOM 1704 CG2 ILE E 231 9.353 21.383 4.537 1.00 11.79 C ANISOU 1704 CG2 ILE E 231 1437 1481 1559 38 -74 -7 C ATOM 1705 CD1 ILE E 231 6.893 23.256 4.408 1.00 16.38 C ANISOU 1705 CD1 ILE E 231 2027 2090 2105 24 -115 -51 C ATOM 1706 N ALA E 232 11.546 20.720 6.711 1.00 8.15 N ANISOU 1706 N ALA E 232 1040 1048 1008 -8 41 -43 N ATOM 1707 CA ALA E 232 12.750 19.941 6.448 1.00 8.08 C ANISOU 1707 CA ALA E 232 968 1048 1054 -31 -3 16 C ATOM 1708 C ALA E 232 12.919 19.679 4.938 1.00 8.29 C ANISOU 1708 C ALA E 232 1041 1057 1051 -18 -28 -13 C ATOM 1709 O ALA E 232 11.958 19.288 4.253 1.00 8.68 O ANISOU 1709 O ALA E 232 1164 1158 976 24 -59 -6 O ATOM 1710 CB ALA E 232 12.716 18.623 7.201 1.00 7.80 C ANISOU 1710 CB ALA E 232 912 997 1055 -22 -2 47 C ATOM 1711 N THR E 233 14.128 19.917 4.422 1.00 8.90 N ANISOU 1711 N THR E 233 1081 1127 1174 -17 12 17 N ATOM 1712 CA THR E 233 14.434 19.648 3.005 1.00 9.87 C ANISOU 1712 CA THR E 233 1263 1258 1227 1 -6 -1 C ATOM 1713 C THR E 233 15.268 18.375 2.829 1.00 10.22 C ANISOU 1713 C THR E 233 1334 1287 1261 20 4 -13 C ATOM 1714 O THR E 233 15.626 17.996 1.704 1.00 10.77 O ANISOU 1714 O THR E 233 1553 1330 1209 38 56 29 O ATOM 1715 CB THR E 233 15.182 20.820 2.312 1.00 10.03 C ANISOU 1715 CB THR E 233 1303 1264 1242 -8 -7 -10 C ATOM 1716 OG1 THR E 233 16.426 21.055 2.968 1.00 12.20 O ANISOU 1716 OG1 THR E 233 1432 1562 1638 -27 -71 65 O ATOM 1717 CG2 THR E 233 14.428 22.137 2.457 1.00 11.22 C ANISOU 1717 CG2 THR E 233 1465 1356 1441 37 5 2 C ATOM 1718 N LYS E 234 15.612 17.749 3.947 1.00 10.65 N ANISOU 1718 N LYS E 234 1384 1364 1296 38 70 35 N ATOM 1719 CA LYS E 234 16.331 16.488 3.965 1.00 10.95 C ANISOU 1719 CA LYS E 234 1398 1378 1384 21 37 35 C ATOM 1720 C LYS E 234 15.765 15.725 5.151 1.00 10.59 C ANISOU 1720 C LYS E 234 1368 1354 1300 46 42 12 C ATOM 1721 O LYS E 234 15.134 16.327 6.032 1.00 10.66 O ANISOU 1721 O LYS E 234 1353 1374 1323 151 131 64 O ATOM 1722 CB LYS E 234 17.838 16.708 4.182 1.00 11.41 C ANISOU 1722 CB LYS E 234 1411 1439 1483 17 37 64 C ATOM 1723 CG LYS E 234 18.208 17.232 5.565 1.00 12.95 C ANISOU 1723 CG LYS E 234 1683 1600 1636 26 5 25 C ATOM 1724 CD LYS E 234 19.720 17.318 5.806 1.00 14.53 C ANISOU 1724 CD LYS E 234 1794 1817 1908 5 31 50 C ATOM 1725 CE LYS E 234 20.042 17.554 7.281 1.00 15.45 C ANISOU 1725 CE LYS E 234 1911 1960 1997 35 0 0 C ATOM 1726 NZ LYS E 234 21.427 18.060 7.560 1.00 17.28 N ANISOU 1726 NZ LYS E 234 2113 2208 2243 -41 -67 18 N ATOM 1727 N GLN E 235 15.985 14.415 5.197 1.00 10.67 N ANISOU 1727 N GLN E 235 1336 1361 1356 29 47 37 N ATOM 1728 CA GLN E 235 15.578 13.652 6.368 1.00 10.17 C ANISOU 1728 CA GLN E 235 1243 1323 1298 11 0 23 C ATOM 1729 C GLN E 235 16.537 13.946 7.533 1.00 9.44 C ANISOU 1729 C GLN E 235 1143 1212 1231 21 -2 48 C ATOM 1730 O GLN E 235 17.760 14.099 7.331 1.00 10.20 O ANISOU 1730 O GLN E 235 1183 1325 1366 84 5 102 O ATOM 1731 CB GLN E 235 15.566 12.158 6.067 1.00 10.99 C ANISOU 1731 CB GLN E 235 1343 1402 1428 27 0 8 C ATOM 1732 CG GLN E 235 15.055 11.286 7.212 1.00 12.34 C ANISOU 1732 CG GLN E 235 1565 1614 1508 45 26 62 C ATOM 1733 CD GLN E 235 14.532 9.943 6.746 1.00 14.27 C ANISOU 1733 CD GLN E 235 1785 1785 1849 10 19 -22 C ATOM 1734 OE1 GLN E 235 13.776 9.866 5.779 1.00 16.13 O ANISOU 1734 OE1 GLN E 235 2037 2077 2014 64 -36 57 O ATOM 1735 NE2 GLN E 235 14.933 8.879 7.428 1.00 16.24 N ANISOU 1735 NE2 GLN E 235 2105 2017 2048 59 23 125 N ATOM 1736 N PHE E 236 15.978 14.068 8.729 1.00 8.63 N ANISOU 1736 N PHE E 236 1037 1068 1172 0 -19 50 N ATOM 1737 CA PHE E 236 16.752 14.210 9.955 1.00 8.41 C ANISOU 1737 CA PHE E 236 985 1085 1122 -8 0 46 C ATOM 1738 C PHE E 236 16.545 12.917 10.712 1.00 8.65 C ANISOU 1738 C PHE E 236 1051 1091 1142 -32 -60 55 C ATOM 1739 O PHE E 236 15.459 12.317 10.652 1.00 9.61 O ANISOU 1739 O PHE E 236 996 1303 1353 -20 -33 200 O ATOM 1740 CB PHE E 236 16.291 15.379 10.826 1.00 8.37 C ANISOU 1740 CB PHE E 236 1040 1093 1047 -11 -60 20 C ATOM 1741 CG PHE E 236 16.698 16.716 10.310 1.00 9.02 C ANISOU 1741 CG PHE E 236 1119 1134 1173 -17 26 12 C ATOM 1742 CD1 PHE E 236 17.821 17.351 10.809 1.00 9.77 C ANISOU 1742 CD1 PHE E 236 1180 1255 1275 21 -18 21 C ATOM 1743 CD2 PHE E 236 15.959 17.343 9.323 1.00 10.56 C ANISOU 1743 CD2 PHE E 236 1191 1346 1474 -7 -35 127 C ATOM 1744 CE1 PHE E 236 18.199 18.586 10.349 1.00 10.24 C ANISOU 1744 CE1 PHE E 236 1350 1285 1253 -5 -49 19 C ATOM 1745 CE2 PHE E 236 16.353 18.595 8.834 1.00 11.49 C ANISOU 1745 CE2 PHE E 236 1363 1377 1623 1 -49 90 C ATOM 1746 CZ PHE E 236 17.464 19.209 9.344 1.00 10.67 C ANISOU 1746 CZ PHE E 236 1354 1280 1419 26 -64 37 C ATOM 1747 N SER E 237 17.590 12.448 11.372 1.00 8.10 N ANISOU 1747 N SER E 237 936 1055 1085 -4 0 37 N ATOM 1748 CA SER E 237 17.495 11.235 12.164 1.00 7.94 C ANISOU 1748 CA SER E 237 1004 1010 1002 2 -12 16 C ATOM 1749 C SER E 237 17.297 11.611 13.621 1.00 7.56 C ANISOU 1749 C SER E 237 963 931 977 -5 -2 -11 C ATOM 1750 O SER E 237 17.765 12.653 14.065 1.00 6.80 O ANISOU 1750 O SER E 237 846 851 884 -17 -3 -11 O ATOM 1751 CB SER E 237 18.776 10.417 12.036 1.00 8.16 C ANISOU 1751 CB SER E 237 1015 1054 1028 36 -12 32 C ATOM 1752 OG SER E 237 18.931 9.920 10.715 1.00 10.08 O ANISOU 1752 OG SER E 237 1467 1247 1116 112 10 71 O ATOM 1753 N ARG E 238 16.609 10.753 14.366 1.00 7.19 N ANISOU 1753 N ARG E 238 889 922 918 -18 -34 -4 N ATOM 1754 CA ARG E 238 16.420 10.965 15.783 1.00 7.64 C ANISOU 1754 CA ARG E 238 975 957 970 2 15 -6 C ATOM 1755 C ARG E 238 17.760 11.290 16.440 1.00 7.38 C ANISOU 1755 C ARG E 238 977 925 902 16 23 22 C ATOM 1756 O ARG E 238 18.762 10.618 16.201 1.00 6.96 O ANISOU 1756 O ARG E 238 929 927 788 58 8 125 O ATOM 1757 CB ARG E 238 15.802 9.724 16.407 1.00 8.15 C ANISOU 1757 CB ARG E 238 1025 991 1080 18 3 20 C ATOM 1758 CG ARG E 238 15.484 9.863 17.861 1.00 11.49 C ANISOU 1758 CG ARG E 238 1505 1505 1355 48 18 -74 C ATOM 1759 CD ARG E 238 14.942 8.591 18.470 1.00 17.18 C ANISOU 1759 CD ARG E 238 2189 2052 2283 -77 122 77 C ATOM 1760 NE ARG E 238 15.492 8.371 19.802 1.00 22.34 N ANISOU 1760 NE ARG E 238 2823 2924 2739 -1 -80 53 N ATOM 1761 CZ ARG E 238 14.844 8.588 20.945 1.00 25.76 C ANISOU 1761 CZ ARG E 238 3277 3341 3170 11 84 -29 C ATOM 1762 NH1 ARG E 238 13.594 9.026 20.947 1.00 27.59 N ANISOU 1762 NH1 ARG E 238 3417 3526 3540 43 14 1 N ATOM 1763 NH2 ARG E 238 15.451 8.357 22.099 1.00 27.30 N ANISOU 1763 NH2 ARG E 238 3479 3511 3382 19 -15 32 N ATOM 1764 N GLY E 239 17.776 12.344 17.252 1.00 7.24 N ANISOU 1764 N GLY E 239 958 901 890 8 20 -4 N ATOM 1765 CA GLY E 239 18.980 12.759 17.940 1.00 7.31 C ANISOU 1765 CA GLY E 239 912 957 907 10 -13 13 C ATOM 1766 C GLY E 239 19.812 13.794 17.213 1.00 7.35 C ANISOU 1766 C GLY E 239 937 921 935 -14 -13 -5 C ATOM 1767 O GLY E 239 20.712 14.434 17.817 1.00 7.55 O ANISOU 1767 O GLY E 239 928 1090 850 -40 -43 35 O ATOM 1768 N ASP E 240 19.544 13.967 15.922 1.00 7.63 N ANISOU 1768 N ASP E 240 928 958 1012 -3 2 31 N ATOM 1769 CA ASP E 240 20.308 14.926 15.136 1.00 8.14 C ANISOU 1769 CA ASP E 240 983 999 1109 -7 30 17 C ATOM 1770 C ASP E 240 20.069 16.350 15.621 1.00 7.98 C ANISOU 1770 C ASP E 240 960 967 1102 10 14 27 C ATOM 1771 O ASP E 240 18.951 16.727 15.982 1.00 7.32 O ANISOU 1771 O ASP E 240 840 871 1069 -51 -1 -10 O ATOM 1772 CB ASP E 240 19.890 14.922 13.677 1.00 8.48 C ANISOU 1772 CB ASP E 240 1086 1020 1114 -26 35 29 C ATOM 1773 CG ASP E 240 20.459 13.764 12.867 1.00 10.24 C ANISOU 1773 CG ASP E 240 1256 1242 1392 16 62 -2 C ATOM 1774 OD1 ASP E 240 21.328 12.990 13.364 1.00 11.76 O ANISOU 1774 OD1 ASP E 240 1354 1472 1641 -23 -38 77 O ATOM 1775 OD2 ASP E 240 20.063 13.571 11.684 1.00 13.03 O ANISOU 1775 OD2 ASP E 240 1542 1735 1673 7 -1 7 O ATOM 1776 N PHE E 241 21.123 17.152 15.568 1.00 8.38 N ANISOU 1776 N PHE E 241 977 1013 1192 21 -15 28 N ATOM 1777 CA PHE E 241 21.010 18.582 15.775 1.00 8.38 C ANISOU 1777 CA PHE E 241 1053 1025 1103 -8 -16 10 C ATOM 1778 C PHE E 241 20.189 19.136 14.610 1.00 8.05 C ANISOU 1778 C PHE E 241 1032 1001 1025 -8 -22 -10 C ATOM 1779 O PHE E 241 20.430 18.788 13.437 1.00 9.26 O ANISOU 1779 O PHE E 241 1194 1150 1172 109 1 -9 O ATOM 1780 CB PHE E 241 22.401 19.208 15.742 1.00 8.87 C ANISOU 1780 CB PHE E 241 1102 1098 1169 -4 -17 29 C ATOM 1781 CG PHE E 241 22.404 20.710 15.802 1.00 9.77 C ANISOU 1781 CG PHE E 241 1227 1167 1317 4 1 9 C ATOM 1782 CD1 PHE E 241 22.489 21.361 17.015 1.00 11.94 C ANISOU 1782 CD1 PHE E 241 1643 1422 1469 1 -29 -19 C ATOM 1783 CD2 PHE E 241 22.341 21.469 14.636 1.00 10.80 C ANISOU 1783 CD2 PHE E 241 1324 1356 1423 53 30 10 C ATOM 1784 CE1 PHE E 241 22.526 22.753 17.075 1.00 12.16 C ANISOU 1784 CE1 PHE E 241 1718 1394 1507 47 39 14 C ATOM 1785 CE2 PHE E 241 22.374 22.853 14.691 1.00 11.08 C ANISOU 1785 CE2 PHE E 241 1350 1365 1492 -1 98 34 C ATOM 1786 CZ PHE E 241 22.460 23.494 15.904 1.00 10.69 C ANISOU 1786 CZ PHE E 241 1215 1403 1442 -17 10 17 C ATOM 1787 N VAL E 242 19.234 20.003 14.922 1.00 7.81 N ANISOU 1787 N VAL E 242 1015 1013 940 -2 -31 -35 N ATOM 1788 CA VAL E 242 18.424 20.647 13.901 1.00 8.44 C ANISOU 1788 CA VAL E 242 1106 1072 1028 13 5 11 C ATOM 1789 C VAL E 242 18.845 22.116 13.746 1.00 8.52 C ANISOU 1789 C VAL E 242 1118 1070 1048 20 9 -15 C ATOM 1790 O VAL E 242 19.321 22.540 12.673 1.00 9.40 O ANISOU 1790 O VAL E 242 1303 1079 1189 9 58 65 O ATOM 1791 CB VAL E 242 16.933 20.528 14.234 1.00 8.93 C ANISOU 1791 CB VAL E 242 1144 1133 1112 -14 -60 -14 C ATOM 1792 CG1 VAL E 242 16.109 21.304 13.261 1.00 10.73 C ANISOU 1792 CG1 VAL E 242 1387 1310 1379 105 -26 54 C ATOM 1793 CG2 VAL E 242 16.498 19.055 14.232 1.00 8.64 C ANISOU 1793 CG2 VAL E 242 1032 1105 1143 17 -36 -23 C ATOM 1794 N VAL E 243 18.723 22.883 14.825 1.00 9.03 N ANISOU 1794 N VAL E 243 1158 1167 1103 34 15 13 N ATOM 1795 CA VAL E 243 19.015 24.308 14.772 1.00 9.62 C ANISOU 1795 CA VAL E 243 1231 1220 1202 13 4 -14 C ATOM 1796 C VAL E 243 19.132 24.890 16.187 1.00 9.51 C ANISOU 1796 C VAL E 243 1231 1176 1205 38 21 5 C ATOM 1797 O VAL E 243 18.615 24.321 17.138 1.00 9.98 O ANISOU 1797 O VAL E 243 1383 1085 1323 37 95 -8 O ATOM 1798 CB VAL E 243 17.889 25.017 13.963 1.00 10.77 C ANISOU 1798 CB VAL E 243 1343 1354 1392 51 -28 -35 C ATOM 1799 CG1 VAL E 243 16.621 25.076 14.755 1.00 11.45 C ANISOU 1799 CG1 VAL E 243 1395 1464 1489 68 2 52 C ATOM 1800 CG2 VAL E 243 18.303 26.359 13.474 1.00 11.51 C ANISOU 1800 CG2 VAL E 243 1556 1500 1316 60 -1 34 C ATOM 1801 N GLU E 244 19.817 26.015 16.320 1.00 9.30 N ANISOU 1801 N GLU E 244 1210 1137 1186 21 37 32 N ATOM 1802 CA GLU E 244 19.870 26.735 17.581 1.00 9.67 C ANISOU 1802 CA GLU E 244 1288 1173 1210 27 2 24 C ATOM 1803 C GLU E 244 18.689 27.697 17.632 1.00 9.39 C ANISOU 1803 C GLU E 244 1228 1187 1151 41 15 18 C ATOM 1804 O GLU E 244 18.264 28.210 16.599 1.00 10.82 O ANISOU 1804 O GLU E 244 1522 1348 1238 148 -6 -45 O ATOM 1805 CB GLU E 244 21.167 27.539 17.726 1.00 10.04 C ANISOU 1805 CB GLU E 244 1285 1225 1303 27 2 52 C ATOM 1806 CG GLU E 244 21.211 28.362 19.006 1.00 11.87 C ANISOU 1806 CG GLU E 244 1579 1425 1504 30 2 -6 C ATOM 1807 CD GLU E 244 22.529 29.094 19.275 1.00 14.00 C ANISOU 1807 CD GLU E 244 1699 1788 1831 29 -21 -41 C ATOM 1808 OE1 GLU E 244 23.441 29.116 18.419 1.00 17.13 O ANISOU 1808 OE1 GLU E 244 2137 2145 2223 45 115 30 O ATOM 1809 OE2 GLU E 244 22.644 29.674 20.377 1.00 13.31 O ANISOU 1809 OE2 GLU E 244 1528 1790 1738 -12 -71 -61 O ATOM 1810 N TYR E 245 18.117 27.912 18.812 1.00 8.87 N ANISOU 1810 N TYR E 245 1214 1100 1054 72 -19 5 N ATOM 1811 CA TYR E 245 17.134 28.977 18.959 1.00 8.34 C ANISOU 1811 CA TYR E 245 1113 1053 1002 40 4 -10 C ATOM 1812 C TYR E 245 17.993 30.193 19.286 1.00 8.96 C ANISOU 1812 C TYR E 245 1158 1143 1100 8 -11 -13 C ATOM 1813 O TYR E 245 18.353 30.415 20.450 1.00 8.72 O ANISOU 1813 O TYR E 245 1162 1091 1059 -4 12 4 O ATOM 1814 CB TYR E 245 16.128 28.723 20.069 1.00 7.77 C ANISOU 1814 CB TYR E 245 927 952 1073 -9 26 -10 C ATOM 1815 CG TYR E 245 15.013 29.761 20.064 1.00 6.73 C ANISOU 1815 CG TYR E 245 876 803 876 -17 -47 -14 C ATOM 1816 CD1 TYR E 245 13.854 29.556 19.341 1.00 7.58 C ANISOU 1816 CD1 TYR E 245 926 1028 926 10 -10 -20 C ATOM 1817 CD2 TYR E 245 15.115 30.934 20.786 1.00 6.52 C ANISOU 1817 CD2 TYR E 245 895 846 734 36 -41 -41 C ATOM 1818 CE1 TYR E 245 12.858 30.489 19.318 1.00 6.96 C ANISOU 1818 CE1 TYR E 245 850 1058 736 22 -14 39 C ATOM 1819 CE2 TYR E 245 14.112 31.884 20.751 1.00 5.65 C ANISOU 1819 CE2 TYR E 245 679 776 689 -52 67 -57 C ATOM 1820 CZ TYR E 245 12.973 31.656 20.029 1.00 7.36 C ANISOU 1820 CZ TYR E 245 850 956 988 13 22 8 C ATOM 1821 OH TYR E 245 11.937 32.606 20.029 1.00 7.72 O ANISOU 1821 OH TYR E 245 882 994 1055 19 -80 -33 O ATOM 1822 N HIS E 246 18.373 30.938 18.243 1.00 9.88 N ANISOU 1822 N HIS E 246 1314 1245 1194 22 -11 9 N ATOM 1823 CA HIS E 246 19.338 32.026 18.348 1.00 10.90 C ANISOU 1823 CA HIS E 246 1417 1363 1359 -9 -7 7 C ATOM 1824 C HIS E 246 18.674 33.379 18.530 1.00 11.64 C ANISOU 1824 C HIS E 246 1486 1424 1510 -12 -6 26 C ATOM 1825 O HIS E 246 17.729 33.714 17.826 1.00 12.95 O ANISOU 1825 O HIS E 246 1671 1514 1735 36 -79 -48 O ATOM 1826 CB HIS E 246 20.207 32.073 17.080 1.00 11.73 C ANISOU 1826 CB HIS E 246 1537 1458 1459 23 15 22 C ATOM 1827 CG HIS E 246 21.517 32.783 17.249 1.00 13.32 C ANISOU 1827 CG HIS E 246 1686 1711 1661 -17 11 -8 C ATOM 1828 ND1 HIS E 246 21.750 34.047 16.753 1.00 16.24 N ANISOU 1828 ND1 HIS E 246 2065 1947 2158 37 -16 0 N ATOM 1829 CD2 HIS E 246 22.677 32.387 17.824 1.00 15.01 C ANISOU 1829 CD2 HIS E 246 1791 1920 1989 -5 -47 14 C ATOM 1830 CE1 HIS E 246 22.995 34.405 17.022 1.00 15.89 C ANISOU 1830 CE1 HIS E 246 2027 1947 2061 -64 -22 -12 C ATOM 1831 NE2 HIS E 246 23.577 33.417 17.680 1.00 16.94 N ANISOU 1831 NE2 HIS E 246 2129 2048 2258 19 -8 0 N ATOM 1832 N GLY E 247 19.231 34.181 19.427 1.00 12.28 N ANISOU 1832 N GLY E 247 1631 1554 1480 44 16 3 N ATOM 1833 CA GLY E 247 18.730 35.518 19.655 1.00 12.90 C ANISOU 1833 CA GLY E 247 1669 1604 1628 3 -1 -17 C ATOM 1834 C GLY E 247 19.650 36.204 20.632 1.00 13.35 C ANISOU 1834 C GLY E 247 1689 1691 1690 14 -22 -27 C ATOM 1835 O GLY E 247 20.794 35.784 20.797 1.00 14.14 O ANISOU 1835 O GLY E 247 1735 1758 1877 -7 -47 -102 O ATOM 1836 N ASP E 248 19.171 37.252 21.287 1.00 13.55 N ANISOU 1836 N ASP E 248 1750 1722 1674 24 20 10 N ATOM 1837 CA ASP E 248 19.997 37.915 22.280 1.00 13.60 C ANISOU 1837 CA ASP E 248 1699 1762 1704 -36 22 11 C ATOM 1838 C ASP E 248 19.692 37.382 23.689 1.00 12.43 C ANISOU 1838 C ASP E 248 1553 1596 1572 -18 -2 -13 C ATOM 1839 O ASP E 248 18.529 37.331 24.120 1.00 11.60 O ANISOU 1839 O ASP E 248 1459 1491 1456 -50 -27 -26 O ATOM 1840 CB ASP E 248 19.930 39.441 22.166 1.00 15.45 C ANISOU 1840 CB ASP E 248 2009 1936 1923 46 0 8 C ATOM 1841 CG ASP E 248 18.576 40.012 22.427 1.00 18.69 C ANISOU 1841 CG ASP E 248 2280 2435 2385 75 42 22 C ATOM 1842 OD1 ASP E 248 17.569 39.417 22.018 1.00 23.45 O ANISOU 1842 OD1 ASP E 248 2810 2962 3138 21 -76 -55 O ATOM 1843 OD2 ASP E 248 18.442 41.117 23.014 1.00 24.26 O ANISOU 1843 OD2 ASP E 248 3243 2896 3079 161 22 -117 O ATOM 1844 N LEU E 249 20.750 36.931 24.362 1.00 11.53 N ANISOU 1844 N LEU E 249 1481 1463 1437 -38 43 42 N ATOM 1845 CA LEU E 249 20.664 36.350 25.705 1.00 10.96 C ANISOU 1845 CA LEU E 249 1380 1425 1359 -25 -2 -7 C ATOM 1846 C LEU E 249 20.628 37.442 26.774 1.00 10.55 C ANISOU 1846 C LEU E 249 1300 1336 1371 -18 23 8 C ATOM 1847 O LEU E 249 21.562 38.237 26.883 1.00 10.32 O ANISOU 1847 O LEU E 249 1287 1272 1362 -97 47 -61 O ATOM 1848 CB LEU E 249 21.853 35.414 25.933 1.00 11.42 C ANISOU 1848 CB LEU E 249 1497 1445 1394 22 44 2 C ATOM 1849 CG LEU E 249 21.918 34.665 27.264 1.00 12.19 C ANISOU 1849 CG LEU E 249 1539 1615 1475 6 0 31 C ATOM 1850 CD1 LEU E 249 20.716 33.748 27.409 1.00 12.03 C ANISOU 1850 CD1 LEU E 249 1545 1534 1489 18 66 31 C ATOM 1851 CD2 LEU E 249 23.204 33.878 27.342 1.00 13.76 C ANISOU 1851 CD2 LEU E 249 1769 1724 1734 69 13 9 C ATOM 1852 N ILE E 250 19.559 37.454 27.567 1.00 9.63 N ANISOU 1852 N ILE E 250 1238 1235 1183 -20 17 17 N ATOM 1853 CA ILE E 250 19.345 38.462 28.591 1.00 9.53 C ANISOU 1853 CA ILE E 250 1193 1231 1194 -39 11 1 C ATOM 1854 C ILE E 250 18.835 37.845 29.896 1.00 9.44 C ANISOU 1854 C ILE E 250 1209 1215 1162 -28 5 -2 C ATOM 1855 O ILE E 250 18.396 36.701 29.923 1.00 8.61 O ANISOU 1855 O ILE E 250 1090 1210 971 -92 -30 -68 O ATOM 1856 CB ILE E 250 18.342 39.501 28.089 1.00 9.43 C ANISOU 1856 CB ILE E 250 1235 1207 1141 -5 13 -15 C ATOM 1857 CG1 ILE E 250 17.009 38.832 27.757 1.00 10.05 C ANISOU 1857 CG1 ILE E 250 1257 1306 1253 -4 21 28 C ATOM 1858 CG2 ILE E 250 18.901 40.228 26.851 1.00 10.47 C ANISOU 1858 CG2 ILE E 250 1366 1327 1283 37 72 16 C ATOM 1859 CD1 ILE E 250 15.942 39.806 27.367 1.00 11.18 C ANISOU 1859 CD1 ILE E 250 1447 1421 1378 79 34 -39 C ATOM 1860 N GLU E 251 18.914 38.602 30.988 1.00 9.38 N ANISOU 1860 N GLU E 251 1157 1267 1138 -46 0 -28 N ATOM 1861 CA GLU E 251 18.421 38.106 32.267 1.00 10.43 C ANISOU 1861 CA GLU E 251 1287 1379 1294 -11 21 52 C ATOM 1862 C GLU E 251 16.962 38.471 32.451 1.00 10.12 C ANISOU 1862 C GLU E 251 1236 1348 1259 -13 16 57 C ATOM 1863 O GLU E 251 16.412 39.255 31.693 1.00 9.27 O ANISOU 1863 O GLU E 251 1030 1336 1154 -37 96 109 O ATOM 1864 CB GLU E 251 19.238 38.665 33.416 1.00 11.04 C ANISOU 1864 CB GLU E 251 1438 1449 1305 -30 -8 36 C ATOM 1865 CG GLU E 251 20.707 38.304 33.344 1.00 15.31 C ANISOU 1865 CG GLU E 251 1824 2019 1974 118 70 103 C ATOM 1866 CD GLU E 251 21.595 39.273 34.106 1.00 19.38 C ANISOU 1866 CD GLU E 251 2437 2428 2498 -13 -50 -16 C ATOM 1867 OE1 GLU E 251 21.302 39.604 35.287 1.00 22.10 O ANISOU 1867 OE1 GLU E 251 2821 2866 2709 11 52 35 O ATOM 1868 OE2 GLU E 251 22.609 39.724 33.519 1.00 22.34 O ANISOU 1868 OE2 GLU E 251 2676 2885 2926 -20 98 93 O ATOM 1869 N ILE E 252 16.347 37.915 33.489 1.00 10.49 N ANISOU 1869 N ILE E 252 1281 1402 1299 -17 14 115 N ATOM 1870 CA ILE E 252 14.909 38.058 33.695 1.00 11.23 C ANISOU 1870 CA ILE E 252 1374 1460 1432 13 38 85 C ATOM 1871 C ILE E 252 14.375 39.485 33.831 1.00 11.17 C ANISOU 1871 C ILE E 252 1394 1439 1410 -21 20 73 C ATOM 1872 O ILE E 252 13.319 39.787 33.284 1.00 11.13 O ANISOU 1872 O ILE E 252 1370 1401 1456 1 20 150 O ATOM 1873 CB ILE E 252 14.446 37.187 34.905 1.00 11.84 C ANISOU 1873 CB ILE E 252 1456 1500 1540 4 53 117 C ATOM 1874 CG1 ILE E 252 12.916 37.116 34.951 1.00 13.03 C ANISOU 1874 CG1 ILE E 252 1521 1723 1705 24 49 115 C ATOM 1875 CG2 ILE E 252 15.031 37.671 36.191 1.00 12.73 C ANISOU 1875 CG2 ILE E 252 1557 1633 1645 7 57 95 C ATOM 1876 CD1 ILE E 252 12.394 36.081 35.932 1.00 13.90 C ANISOU 1876 CD1 ILE E 252 1727 1718 1835 5 48 133 C ATOM 1877 N THR E 253 15.074 40.366 34.527 1.00 11.45 N ANISOU 1877 N THR E 253 1451 1456 1442 -4 5 28 N ATOM 1878 CA THR E 253 14.534 41.711 34.722 1.00 12.05 C ANISOU 1878 CA THR E 253 1506 1537 1532 0 3 34 C ATOM 1879 C THR E 253 14.453 42.442 33.390 1.00 11.80 C ANISOU 1879 C THR E 253 1492 1504 1486 -4 -9 18 C ATOM 1880 O THR E 253 13.471 43.132 33.123 1.00 11.48 O ANISOU 1880 O THR E 253 1481 1459 1419 -2 -10 65 O ATOM 1881 CB THR E 253 15.349 42.517 35.727 1.00 12.44 C ANISOU 1881 CB THR E 253 1557 1601 1568 -5 -13 35 C ATOM 1882 OG1 THR E 253 16.706 42.598 35.283 1.00 15.00 O ANISOU 1882 OG1 THR E 253 1746 2019 1932 15 46 104 O ATOM 1883 CG2 THR E 253 15.416 41.805 37.076 1.00 12.32 C ANISOU 1883 CG2 THR E 253 1536 1599 1546 20 13 13 C ATOM 1884 N ASP E 254 15.488 42.297 32.569 1.00 11.77 N ANISOU 1884 N ASP E 254 1514 1474 1481 -7 -13 -7 N ATOM 1885 CA ASP E 254 15.497 42.901 31.241 1.00 12.29 C ANISOU 1885 CA ASP E 254 1573 1556 1540 -7 -21 0 C ATOM 1886 C ASP E 254 14.421 42.264 30.366 1.00 11.65 C ANISOU 1886 C ASP E 254 1505 1468 1454 3 -14 5 C ATOM 1887 O ASP E 254 13.732 42.956 29.629 1.00 11.26 O ANISOU 1887 O ASP E 254 1466 1422 1389 -9 -34 15 O ATOM 1888 CB ASP E 254 16.862 42.729 30.576 1.00 13.01 C ANISOU 1888 CB ASP E 254 1625 1661 1658 -3 -13 -22 C ATOM 1889 CG ASP E 254 16.976 43.501 29.272 1.00 16.48 C ANISOU 1889 CG ASP E 254 2119 2094 2047 35 33 55 C ATOM 1890 OD1 ASP E 254 16.290 43.135 28.294 1.00 20.98 O ANISOU 1890 OD1 ASP E 254 2666 2821 2484 59 -76 2 O ATOM 1891 OD2 ASP E 254 17.719 44.496 29.137 1.00 20.97 O ANISOU 1891 OD2 ASP E 254 2592 2519 2855 -60 101 150 O ATOM 1892 N ALA E 255 14.288 40.943 30.454 1.00 11.14 N ANISOU 1892 N ALA E 255 1447 1428 1356 -15 -24 10 N ATOM 1893 CA ALA E 255 13.314 40.203 29.656 1.00 11.12 C ANISOU 1893 CA ALA E 255 1418 1421 1385 -8 -8 4 C ATOM 1894 C ALA E 255 11.883 40.696 29.914 1.00 11.43 C ANISOU 1894 C ALA E 255 1453 1459 1429 0 -22 -9 C ATOM 1895 O ALA E 255 11.110 40.937 28.982 1.00 11.26 O ANISOU 1895 O ALA E 255 1410 1449 1418 -36 -51 -27 O ATOM 1896 CB ALA E 255 13.447 38.699 29.923 1.00 11.02 C ANISOU 1896 CB ALA E 255 1401 1384 1399 -38 -5 -19 C ATOM 1897 N LYS E 256 11.535 40.860 31.179 1.00 11.80 N ANISOU 1897 N LYS E 256 1516 1521 1444 1 0 0 N ATOM 1898 CA LYS E 256 10.226 41.384 31.529 1.00 12.66 C ANISOU 1898 CA LYS E 256 1586 1633 1592 8 -7 -4 C ATOM 1899 C LYS E 256 9.989 42.766 30.949 1.00 12.98 C ANISOU 1899 C LYS E 256 1644 1669 1618 7 2 12 C ATOM 1900 O LYS E 256 8.918 43.032 30.413 1.00 13.13 O ANISOU 1900 O LYS E 256 1615 1722 1652 25 6 9 O ATOM 1901 CB LYS E 256 10.074 41.441 33.032 1.00 13.17 C ANISOU 1901 CB LYS E 256 1660 1691 1651 19 -1 19 C ATOM 1902 CG LYS E 256 9.825 40.083 33.611 1.00 13.91 C ANISOU 1902 CG LYS E 256 1718 1745 1821 -16 9 39 C ATOM 1903 CD LYS E 256 9.557 40.184 35.071 1.00 14.63 C ANISOU 1903 CD LYS E 256 1865 1848 1844 -22 23 4 C ATOM 1904 CE LYS E 256 9.407 38.814 35.654 1.00 15.13 C ANISOU 1904 CE LYS E 256 1903 1832 2012 -4 -33 31 C ATOM 1905 NZ LYS E 256 9.626 38.828 37.098 1.00 15.40 N ANISOU 1905 NZ LYS E 256 1981 1889 1982 15 72 105 N ATOM 1906 N LYS E 257 10.983 43.639 31.063 1.00 13.57 N ANISOU 1906 N LYS E 257 1709 1746 1700 0 -21 14 N ATOM 1907 CA LYS E 257 10.892 44.995 30.523 1.00 13.74 C ANISOU 1907 CA LYS E 257 1747 1753 1720 7 -10 0 C ATOM 1908 C LYS E 257 10.602 44.955 29.029 1.00 13.65 C ANISOU 1908 C LYS E 257 1724 1743 1716 17 -16 1 C ATOM 1909 O LYS E 257 9.740 45.677 28.529 1.00 13.56 O ANISOU 1909 O LYS E 257 1723 1802 1626 7 -67 -3 O ATOM 1910 CB LYS E 257 12.193 45.764 30.768 1.00 14.11 C ANISOU 1910 CB LYS E 257 1762 1790 1808 0 -5 4 C ATOM 1911 CG LYS E 257 12.492 46.002 32.233 1.00 15.55 C ANISOU 1911 CG LYS E 257 1983 1998 1925 25 -7 17 C ATOM 1912 CD LYS E 257 13.717 46.899 32.442 1.00 17.09 C ANISOU 1912 CD LYS E 257 2131 2152 2209 -28 0 -5 C ATOM 1913 CE LYS E 257 14.081 47.030 33.917 1.00 18.06 C ANISOU 1913 CE LYS E 257 2288 2296 2275 7 -9 7 C ATOM 1914 NZ LYS E 257 15.231 47.950 34.162 1.00 19.13 N ANISOU 1914 NZ LYS E 257 2385 2410 2473 -9 16 15 N ATOM 1915 N ARG E 258 11.346 44.119 28.321 1.00 13.29 N ANISOU 1915 N ARG E 258 1695 1683 1671 -11 -29 -13 N ATOM 1916 CA ARG E 258 11.166 43.967 26.893 1.00 13.48 C ANISOU 1916 CA ARG E 258 1731 1709 1680 18 0 6 C ATOM 1917 C ARG E 258 9.825 43.348 26.576 1.00 14.25 C ANISOU 1917 C ARG E 258 1792 1830 1790 3 -11 -8 C ATOM 1918 O ARG E 258 9.127 43.821 25.677 1.00 14.71 O ANISOU 1918 O ARG E 258 1916 1872 1799 49 5 44 O ATOM 1919 CB ARG E 258 12.254 43.077 26.321 1.00 12.89 C ANISOU 1919 CB ARG E 258 1657 1645 1594 -7 -8 -8 C ATOM 1920 CG ARG E 258 13.594 43.711 26.332 1.00 12.43 C ANISOU 1920 CG ARG E 258 1601 1587 1534 15 -5 16 C ATOM 1921 CD ARG E 258 14.601 42.959 25.536 1.00 11.70 C ANISOU 1921 CD ARG E 258 1468 1467 1510 -32 -24 14 C ATOM 1922 NE ARG E 258 15.937 43.504 25.696 1.00 11.75 N ANISOU 1922 NE ARG E 258 1489 1537 1437 -27 -26 32 N ATOM 1923 CZ ARG E 258 16.964 43.150 24.946 1.00 12.06 C ANISOU 1923 CZ ARG E 258 1537 1525 1520 -5 -1 -18 C ATOM 1924 NH1 ARG E 258 16.787 42.254 23.976 1.00 12.37 N ANISOU 1924 NH1 ARG E 258 1585 1665 1447 25 3 28 N ATOM 1925 NH2 ARG E 258 18.162 43.689 25.165 1.00 12.81 N ANISOU 1925 NH2 ARG E 258 1595 1699 1571 -24 35 79 N ATOM 1926 N GLU E 259 9.463 42.291 27.304 1.00 15.06 N ANISOU 1926 N GLU E 259 1937 1901 1884 22 -10 8 N ATOM 1927 CA GLU E 259 8.204 41.587 27.047 1.00 15.88 C ANISOU 1927 CA GLU E 259 2000 2028 2005 9 -10 -11 C ATOM 1928 C GLU E 259 7.017 42.544 27.189 1.00 16.19 C ANISOU 1928 C GLU E 259 2033 2079 2038 5 -9 3 C ATOM 1929 O GLU E 259 5.997 42.373 26.527 1.00 16.45 O ANISOU 1929 O GLU E 259 2013 2145 2090 2 -29 -1 O ATOM 1930 CB GLU E 259 8.037 40.351 27.950 1.00 16.55 C ANISOU 1930 CB GLU E 259 2094 2135 2059 9 8 13 C ATOM 1931 CG GLU E 259 7.293 39.206 27.278 1.00 18.14 C ANISOU 1931 CG GLU E 259 2283 2285 2323 13 4 -55 C ATOM 1932 CD GLU E 259 6.933 38.072 28.223 1.00 20.29 C ANISOU 1932 CD GLU E 259 2607 2530 2572 -21 55 24 C ATOM 1933 OE1 GLU E 259 7.645 37.869 29.227 1.00 22.87 O ANISOU 1933 OE1 GLU E 259 2762 2983 2941 88 -10 125 O ATOM 1934 OE2 GLU E 259 5.917 37.384 27.965 1.00 21.38 O ANISOU 1934 OE2 GLU E 259 2717 2688 2718 -32 -15 -17 O ATOM 1935 N ALA E 260 7.164 43.557 28.038 1.00 16.27 N ANISOU 1935 N ALA E 260 2046 2068 2068 -2 -6 -1 N ATOM 1936 CA ALA E 260 6.123 44.562 28.227 1.00 16.29 C ANISOU 1936 CA ALA E 260 2056 2068 2063 6 1 2 C ATOM 1937 C ALA E 260 6.137 45.571 27.085 1.00 16.37 C ANISOU 1937 C ALA E 260 2057 2091 2072 0 -4 11 C ATOM 1938 O ALA E 260 5.084 46.012 26.634 1.00 16.86 O ANISOU 1938 O ALA E 260 2083 2166 2156 13 -8 34 O ATOM 1939 CB ALA E 260 6.306 45.278 29.551 1.00 16.38 C ANISOU 1939 CB ALA E 260 2067 2097 2058 -9 -14 11 C ATOM 1940 N LEU E 261 7.327 45.948 26.629 1.00 16.25 N ANISOU 1940 N LEU E 261 2044 2074 2056 3 -10 5 N ATOM 1941 CA LEU E 261 7.450 46.914 25.541 1.00 16.04 C ANISOU 1941 CA LEU E 261 2031 2030 2031 6 -4 -2 C ATOM 1942 C LEU E 261 6.957 46.322 24.223 1.00 15.90 C ANISOU 1942 C LEU E 261 2004 2020 2016 7 -17 10 C ATOM 1943 O LEU E 261 6.281 47.007 23.452 1.00 15.67 O ANISOU 1943 O LEU E 261 1988 1996 1968 18 -27 5 O ATOM 1944 CB LEU E 261 8.894 47.409 25.400 1.00 16.07 C ANISOU 1944 CB LEU E 261 2030 2037 2038 2 -12 0 C ATOM 1945 CG LEU E 261 9.385 48.377 26.489 1.00 16.68 C ANISOU 1945 CG LEU E 261 2118 2107 2111 0 3 -20 C ATOM 1946 CD1 LEU E 261 10.773 48.916 26.144 1.00 17.23 C ANISOU 1946 CD1 LEU E 261 2141 2227 2179 -10 7 -10 C ATOM 1947 CD2 LEU E 261 8.414 49.546 26.730 1.00 16.84 C ANISOU 1947 CD2 LEU E 261 2127 2137 2131 6 -4 7 C ATOM 1948 N TYR E 262 7.292 45.054 23.977 1.00 15.55 N ANISOU 1948 N TYR E 262 1976 1980 1949 -10 -19 -17 N ATOM 1949 CA TYR E 262 6.891 44.362 22.745 1.00 15.46 C ANISOU 1949 CA TYR E 262 1979 1942 1951 -6 -9 -20 C ATOM 1950 C TYR E 262 5.373 44.232 22.639 1.00 16.46 C ANISOU 1950 C TYR E 262 2067 2101 2084 2 -13 -8 C ATOM 1951 O TYR E 262 4.811 44.289 21.539 1.00 16.70 O ANISOU 1951 O TYR E 262 2067 2181 2095 1 -25 21 O ATOM 1952 CB TYR E 262 7.513 42.959 22.688 1.00 15.01 C ANISOU 1952 CB TYR E 262 1877 1921 1904 -12 -12 -11 C ATOM 1953 CG TYR E 262 9.022 42.914 22.531 1.00 12.80 C ANISOU 1953 CG TYR E 262 1710 1570 1582 -5 -45 -33 C ATOM 1954 CD1 TYR E 262 9.763 41.932 23.159 1.00 10.81 C ANISOU 1954 CD1 TYR E 262 1431 1338 1336 -47 -13 -78 C ATOM 1955 CD2 TYR E 262 9.695 43.830 21.741 1.00 12.33 C ANISOU 1955 CD2 TYR E 262 1546 1626 1512 16 -39 -14 C ATOM 1956 CE1 TYR E 262 11.125 41.869 23.022 1.00 10.67 C ANISOU 1956 CE1 TYR E 262 1408 1334 1310 5 -23 -39 C ATOM 1957 CE2 TYR E 262 11.070 43.776 21.597 1.00 12.09 C ANISOU 1957 CE2 TYR E 262 1530 1536 1524 36 -17 28 C ATOM 1958 CZ TYR E 262 11.781 42.782 22.242 1.00 11.01 C ANISOU 1958 CZ TYR E 262 1435 1388 1357 -14 -31 -31 C ATOM 1959 OH TYR E 262 13.160 42.718 22.121 1.00 12.30 O ANISOU 1959 OH TYR E 262 1556 1581 1534 77 66 -79 O ATOM 1960 N ALA E 263 4.721 44.036 23.785 1.00 17.49 N ANISOU 1960 N ALA E 263 2216 2237 2192 0 0 -4 N ATOM 1961 CA ALA E 263 3.269 43.872 23.855 1.00 18.30 C ANISOU 1961 CA ALA E 263 2291 2342 2319 -10 4 -4 C ATOM 1962 C ALA E 263 2.507 45.105 23.368 1.00 19.03 C ANISOU 1962 C ALA E 263 2386 2431 2411 3 -5 12 C ATOM 1963 O ALA E 263 1.364 44.998 22.930 1.00 19.54 O ANISOU 1963 O ALA E 263 2404 2540 2479 -17 -22 15 O ATOM 1964 CB ALA E 263 2.851 43.532 25.279 1.00 18.34 C ANISOU 1964 CB ALA E 263 2296 2355 2318 -11 -4 14 C ATOM 1965 N GLN E 264 3.134 46.274 23.441 1.00 19.52 N ANISOU 1965 N GLN E 264 2467 2479 2469 -5 5 -7 N ATOM 1966 CA GLN E 264 2.485 47.509 23.006 1.00 20.09 C ANISOU 1966 CA GLN E 264 2539 2548 2545 5 1 5 C ATOM 1967 C GLN E 264 2.590 47.679 21.491 1.00 20.41 C ANISOU 1967 C GLN E 264 2588 2589 2576 4 -1 3 C ATOM 1968 O GLN E 264 2.122 48.676 20.943 1.00 20.65 O ANISOU 1968 O GLN E 264 2619 2609 2616 13 0 10 O ATOM 1969 CB GLN E 264 3.093 48.723 23.724 1.00 20.08 C ANISOU 1969 CB GLN E 264 2549 2531 2547 16 4 -6 C ATOM 1970 CG GLN E 264 2.995 48.639 25.248 1.00 20.49 C ANISOU 1970 CG GLN E 264 2614 2582 2587 29 17 11 C ATOM 1971 CD GLN E 264 3.559 49.858 25.958 1.00 21.10 C ANISOU 1971 CD GLN E 264 2672 2677 2667 -21 0 -1 C ATOM 1972 OE1 GLN E 264 3.212 50.995 25.623 1.00 21.60 O ANISOU 1972 OE1 GLN E 264 2747 2715 2742 0 18 10 O ATOM 1973 NE2 GLN E 264 4.423 49.626 26.947 1.00 21.32 N ANISOU 1973 NE2 GLN E 264 2693 2713 2693 -2 -6 11 N ATOM 1974 N ASP E 265 3.189 46.698 20.817 1.00 20.74 N ANISOU 1974 N ASP E 265 2632 2623 2625 4 -2 -8 N ATOM 1975 CA ASP E 265 3.388 46.782 19.376 1.00 20.98 C ANISOU 1975 CA ASP E 265 2666 2652 2652 2 -4 -6 C ATOM 1976 C ASP E 265 2.925 45.515 18.669 1.00 20.84 C ANISOU 1976 C ASP E 265 2647 2635 2635 2 -10 -2 C ATOM 1977 O ASP E 265 3.648 44.524 18.629 1.00 20.73 O ANISOU 1977 O ASP E 265 2662 2609 2604 17 -31 -12 O ATOM 1978 CB ASP E 265 4.862 47.040 19.063 1.00 21.37 C ANISOU 1978 CB ASP E 265 2688 2709 2721 12 0 -2 C ATOM 1979 CG ASP E 265 5.087 47.459 17.623 1.00 22.32 C ANISOU 1979 CG ASP E 265 2829 2852 2798 -3 4 9 C ATOM 1980 OD1 ASP E 265 4.717 48.597 17.266 1.00 23.75 O ANISOU 1980 OD1 ASP E 265 2990 3004 3029 15 13 22 O ATOM 1981 OD2 ASP E 265 5.623 46.720 16.773 1.00 23.47 O ANISOU 1981 OD2 ASP E 265 2970 3032 2913 28 20 -22 O ATOM 1982 N PRO E 266 1.722 45.562 18.099 1.00 20.76 N ANISOU 1982 N PRO E 266 2627 2616 2644 -1 0 -4 N ATOM 1983 CA PRO E 266 1.150 44.418 17.377 1.00 20.60 C ANISOU 1983 CA PRO E 266 2602 2610 2612 0 -3 -7 C ATOM 1984 C PRO E 266 1.981 43.936 16.183 1.00 20.33 C ANISOU 1984 C PRO E 266 2565 2569 2588 -4 2 2 C ATOM 1985 O PRO E 266 1.792 42.805 15.742 1.00 20.79 O ANISOU 1985 O PRO E 266 2604 2626 2667 -15 0 -23 O ATOM 1986 CB PRO E 266 -0.199 44.952 16.888 1.00 20.80 C ATOM 1987 CG PRO E 266 -0.509 46.093 17.751 1.00 20.82 C ANISOU 1987 CG PRO E 266 2630 2637 2641 2 -6 0 C ATOM 1988 CD PRO E 266 0.803 46.711 18.116 1.00 20.84 C ANISOU 1988 CD PRO E 266 2623 2634 2658 -8 -4 -1 C ATOM 1989 N SER E 267 2.871 44.775 15.661 1.00 19.77 N ANISOU 1989 N SER E 267 2507 2505 2498 9 3 0 N ATOM 1990 CA SER E 267 3.740 44.372 14.560 1.00 19.34 C ANISOU 1990 CA SER E 267 2450 2456 2442 13 -4 15 C ATOM 1991 C SER E 267 4.856 43.429 15.037 1.00 18.57 C ANISOU 1991 C SER E 267 2366 2363 2325 12 -4 -9 C ATOM 1992 O SER E 267 5.431 42.683 14.240 1.00 18.49 O ANISOU 1992 O SER E 267 2357 2404 2263 9 -6 -15 O ATOM 1993 CB SER E 267 4.351 45.608 13.902 1.00 19.53 C ANISOU 1993 CB SER E 267 2473 2472 2475 7 15 20 C ATOM 1994 OG SER E 267 3.341 46.405 13.298 1.00 20.30 O ANISOU 1994 OG SER E 267 2528 2610 2575 29 7 59 O ATOM 1995 N THR E 268 5.166 43.479 16.334 1.00 17.78 N ANISOU 1995 N THR E 268 2244 2265 2243 39 4 15 N ATOM 1996 CA THR E 268 6.185 42.613 16.924 1.00 16.93 C ANISOU 1996 CA THR E 268 2146 2143 2141 0 -3 13 C ATOM 1997 C THR E 268 5.562 41.333 17.418 1.00 15.70 C ANISOU 1997 C THR E 268 1990 2015 1959 36 -5 27 C ATOM 1998 O THR E 268 4.575 41.351 18.156 1.00 16.71 O ANISOU 1998 O THR E 268 2064 2176 2107 41 4 57 O ATOM 1999 CB THR E 268 6.868 43.261 18.129 1.00 17.02 C ANISOU 1999 CB THR E 268 2151 2160 2156 19 -5 2 C ATOM 2000 OG1 THR E 268 7.304 44.575 17.797 1.00 17.89 O ANISOU 2000 OG1 THR E 268 2232 2276 2290 -44 -1 47 O ATOM 2001 CG2 THR E 268 8.154 42.520 18.467 1.00 17.39 C ANISOU 2001 CG2 THR E 268 2189 2260 2156 13 -22 -10 C ATOM 2002 N GLY E 269 6.182 40.228 17.055 1.00 13.81 N ANISOU 2002 N GLY E 269 1773 1783 1689 0 -26 32 N ATOM 2003 CA GLY E 269 5.700 38.927 17.458 1.00 12.84 C ANISOU 2003 CA GLY E 269 1610 1676 1592 11 -24 31 C ATOM 2004 C GLY E 269 6.237 38.555 18.823 1.00 11.29 C ANISOU 2004 C GLY E 269 1417 1453 1418 -3 -16 -2 C ATOM 2005 O GLY E 269 6.877 39.368 19.502 1.00 11.40 O ANISOU 2005 O GLY E 269 1455 1450 1423 -47 -63 67 O ATOM 2006 N CYS E 270 5.976 37.314 19.202 1.00 10.34 N ANISOU 2006 N CYS E 270 1263 1358 1304 -10 -36 12 N ATOM 2007 CA CYS E 270 6.363 36.758 20.500 1.00 9.32 C ANISOU 2007 CA CYS E 270 1143 1216 1179 -16 -20 -1 C ATOM 2008 C CYS E 270 7.490 35.757 20.313 1.00 8.92 C ANISOU 2008 C CYS E 270 1087 1149 1152 -39 1 -32 C ATOM 2009 O CYS E 270 7.274 34.611 19.881 1.00 9.78 O ANISOU 2009 O CYS E 270 1121 1274 1320 -13 -48 -17 O ATOM 2010 CB CYS E 270 5.158 36.073 21.159 1.00 9.41 C ANISOU 2010 CB CYS E 270 1140 1195 1240 -5 -12 -30 C ATOM 2011 SG CYS E 270 3.808 37.221 21.520 1.00 11.22 S ANISOU 2011 SG CYS E 270 1263 1468 1531 129 94 65 S ATOM 2012 N TYR E 271 8.706 36.194 20.624 1.00 8.36 N ANISOU 2012 N TYR E 271 1025 1132 1019 24 -59 -22 N ATOM 2013 CA TYR E 271 9.884 35.375 20.360 1.00 8.47 C ANISOU 2013 CA TYR E 271 1042 1116 1059 9 -26 10 C ATOM 2014 C TYR E 271 10.786 35.202 21.587 1.00 8.46 C ANISOU 2014 C TYR E 271 1021 1138 1052 0 -49 -9 C ATOM 2015 O TYR E 271 11.967 34.858 21.448 1.00 10.43 O ANISOU 2015 O TYR E 271 1169 1490 1302 22 -43 -9 O ATOM 2016 CB TYR E 271 10.699 36.022 19.249 1.00 7.99 C ANISOU 2016 CB TYR E 271 1029 1001 1004 4 -12 -25 C ATOM 2017 CG TYR E 271 9.994 36.091 17.918 1.00 8.99 C ANISOU 2017 CG TYR E 271 1190 1167 1058 16 -26 63 C ATOM 2018 CD1 TYR E 271 9.298 37.225 17.531 1.00 9.89 C ANISOU 2018 CD1 TYR E 271 1294 1261 1201 120 3 -53 C ATOM 2019 CD2 TYR E 271 10.048 35.025 17.029 1.00 10.15 C ANISOU 2019 CD2 TYR E 271 1288 1206 1362 -22 -7 0 C ATOM 2020 CE1 TYR E 271 8.664 37.288 16.293 1.00 10.41 C ANISOU 2020 CE1 TYR E 271 1377 1353 1225 42 -60 19 C ATOM 2021 CE2 TYR E 271 9.406 35.077 15.806 1.00 11.14 C ANISOU 2021 CE2 TYR E 271 1556 1297 1379 -11 -37 -96 C ATOM 2022 CZ TYR E 271 8.724 36.210 15.436 1.00 11.14 C ANISOU 2022 CZ TYR E 271 1441 1441 1349 82 -34 -8 C ATOM 2023 OH TYR E 271 8.093 36.272 14.207 1.00 13.13 O ANISOU 2023 OH TYR E 271 1743 1838 1407 40 21 15 O ATOM 2024 N MET E 272 10.242 35.393 22.777 1.00 8.74 N ANISOU 2024 N MET E 272 1017 1181 1123 8 -57 33 N ATOM 2025 CA MET E 272 11.045 35.288 24.002 1.00 8.65 C ANISOU 2025 CA MET E 272 1054 1108 1122 -24 -31 34 C ATOM 2026 C MET E 272 11.025 33.855 24.498 1.00 7.70 C ANISOU 2026 C MET E 272 888 946 1091 -8 -52 32 C ATOM 2027 O MET E 272 9.959 33.257 24.565 1.00 9.38 O ANISOU 2027 O MET E 272 965 1062 1537 -62 -86 155 O ATOM 2028 CB MET E 272 10.494 36.211 25.064 1.00 9.40 C ANISOU 2028 CB MET E 272 1170 1213 1188 -11 -46 -18 C ATOM 2029 CG MET E 272 10.278 37.586 24.539 1.00 12.57 C ANISOU 2029 CG MET E 272 1739 1471 1564 136 -31 -19 C ATOM 2030 SD MET E 272 11.788 38.478 24.375 1.00 16.59 S ANISOU 2030 SD MET E 272 2049 2234 2018 106 -29 -16 S ATOM 2031 CE MET E 272 12.046 39.083 26.007 1.00 16.00 C ANISOU 2031 CE MET E 272 2062 2004 2013 47 6 -58 C ATOM 2032 N TYR E 273 12.189 33.291 24.807 1.00 5.91 N ANISOU 2032 N TYR E 273 665 754 824 -66 -69 35 N ATOM 2033 CA TYR E 273 12.297 31.908 25.271 1.00 5.42 C ANISOU 2033 CA TYR E 273 651 671 735 -20 -46 -54 C ATOM 2034 C TYR E 273 13.038 31.857 26.598 1.00 4.93 C ANISOU 2034 C TYR E 273 606 613 651 0 -2 29 C ATOM 2035 O TYR E 273 14.265 32.039 26.657 1.00 4.84 O ANISOU 2035 O TYR E 273 608 723 506 -55 15 19 O ATOM 2036 CB TYR E 273 13.071 31.108 24.226 1.00 5.13 C ANISOU 2036 CB TYR E 273 599 654 696 3 -36 -52 C ATOM 2037 CG TYR E 273 12.753 29.628 24.174 1.00 4.78 C ANISOU 2037 CG TYR E 273 523 587 706 0 49 55 C ATOM 2038 CD1 TYR E 273 12.811 28.958 22.982 1.00 5.57 C ANISOU 2038 CD1 TYR E 273 787 710 618 -28 -22 18 C ATOM 2039 CD2 TYR E 273 12.413 28.901 25.295 1.00 5.32 C ANISOU 2039 CD2 TYR E 273 673 746 602 5 36 28 C ATOM 2040 CE1 TYR E 273 12.502 27.612 22.878 1.00 4.86 C ANISOU 2040 CE1 TYR E 273 554 618 674 -51 87 8 C ATOM 2041 CE2 TYR E 273 12.117 27.557 25.210 1.00 4.48 C ANISOU 2041 CE2 TYR E 273 653 656 390 74 17 24 C ATOM 2042 CZ TYR E 273 12.164 26.906 24.000 1.00 5.25 C ANISOU 2042 CZ TYR E 273 756 602 635 -37 16 -64 C ATOM 2043 OH TYR E 273 11.839 25.547 23.879 1.00 7.12 O ANISOU 2043 OH TYR E 273 923 717 1064 -82 105 -65 O ATOM 2044 N TYR E 274 12.282 31.642 27.670 1.00 5.15 N ANISOU 2044 N TYR E 274 624 659 673 -21 32 -23 N ATOM 2045 CA TYR E 274 12.807 31.621 29.026 1.00 5.36 C ANISOU 2045 CA TYR E 274 626 662 749 -36 -9 -12 C ATOM 2046 C TYR E 274 13.310 30.245 29.415 1.00 5.63 C ANISOU 2046 C TYR E 274 623 706 809 2 -34 -39 C ATOM 2047 O TYR E 274 12.758 29.225 29.005 1.00 5.84 O ANISOU 2047 O TYR E 274 585 687 946 14 -60 -58 O ATOM 2048 CB TYR E 274 11.716 31.999 30.041 1.00 5.44 C ANISOU 2048 CB TYR E 274 617 655 794 -48 -30 1 C ATOM 2049 CG TYR E 274 11.275 33.441 29.968 1.00 6.26 C ANISOU 2049 CG TYR E 274 751 706 921 -8 22 -21 C ATOM 2050 CD1 TYR E 274 10.291 33.846 29.085 1.00 6.89 C ANISOU 2050 CD1 TYR E 274 811 841 965 3 -26 -4 C ATOM 2051 CD2 TYR E 274 11.882 34.408 30.748 1.00 6.94 C ANISOU 2051 CD2 TYR E 274 822 812 1003 -56 -92 -23 C ATOM 2052 CE1 TYR E 274 9.896 35.177 29.023 1.00 8.15 C ANISOU 2052 CE1 TYR E 274 1055 953 1090 47 -40 68 C ATOM 2053 CE2 TYR E 274 11.489 35.740 30.693 1.00 7.27 C ANISOU 2053 CE2 TYR E 274 808 877 1076 -2 -31 25 C ATOM 2054 CZ TYR E 274 10.500 36.111 29.818 1.00 8.70 C ANISOU 2054 CZ TYR E 274 1044 1051 1207 -2 -60 64 C ATOM 2055 OH TYR E 274 10.113 37.433 29.773 1.00 10.33 O ANISOU 2055 OH TYR E 274 1221 1171 1532 57 -102 80 O ATOM 2056 N PHE E 275 14.346 30.236 30.250 1.00 5.29 N ANISOU 2056 N PHE E 275 626 710 672 -32 -64 -41 N ATOM 2057 CA PHE E 275 14.909 28.995 30.740 1.00 6.03 C ANISOU 2057 CA PHE E 275 704 763 822 -18 -31 4 C ATOM 2058 C PHE E 275 15.730 29.233 31.997 1.00 6.27 C ANISOU 2058 C PHE E 275 763 813 805 -23 -4 -7 C ATOM 2059 O PHE E 275 16.083 30.358 32.311 1.00 5.96 O ANISOU 2059 O PHE E 275 659 832 774 -43 -20 41 O ATOM 2060 CB PHE E 275 15.770 28.324 29.671 1.00 6.19 C ANISOU 2060 CB PHE E 275 746 798 806 -16 21 30 C ATOM 2061 CG PHE E 275 17.033 29.078 29.325 1.00 6.71 C ANISOU 2061 CG PHE E 275 729 845 974 -20 -19 34 C ATOM 2062 CD1 PHE E 275 18.234 28.758 29.946 1.00 7.98 C ANISOU 2062 CD1 PHE E 275 910 1041 1078 57 -45 48 C ATOM 2063 CD2 PHE E 275 17.028 30.085 28.384 1.00 7.25 C ANISOU 2063 CD2 PHE E 275 958 907 888 31 -44 -74 C ATOM 2064 CE1 PHE E 275 19.396 29.427 29.625 1.00 8.32 C ANISOU 2064 CE1 PHE E 275 991 1063 1107 2 -30 31 C ATOM 2065 CE2 PHE E 275 18.186 30.761 28.058 1.00 8.03 C ANISOU 2065 CE2 PHE E 275 998 1092 960 77 50 86 C ATOM 2066 CZ PHE E 275 19.373 30.444 28.684 1.00 8.48 C ANISOU 2066 CZ PHE E 275 1047 1132 1044 9 15 -5 C ATOM 2067 N GLN E 276 15.985 28.155 32.725 1.00 7.93 N ANISOU 2067 N GLN E 276 991 944 1074 14 -14 20 N ATOM 2068 CA GLN E 276 16.767 28.202 33.942 1.00 8.84 C ANISOU 2068 CA GLN E 276 1125 1107 1125 12 -12 10 C ATOM 2069 C GLN E 276 18.163 27.655 33.698 1.00 8.69 C ANISOU 2069 C GLN E 276 1125 1128 1045 6 -5 -2 C ATOM 2070 O GLN E 276 18.355 26.672 32.985 1.00 8.49 O ANISOU 2070 O GLN E 276 1064 991 1172 -28 58 69 O ATOM 2071 CB GLN E 276 16.057 27.449 35.064 1.00 9.50 C ANISOU 2071 CB GLN E 276 1222 1241 1145 -9 -39 23 C ATOM 2072 CG GLN E 276 14.721 28.103 35.426 1.00 12.14 C ANISOU 2072 CG GLN E 276 1495 1627 1490 114 -14 -12 C ATOM 2073 CD GLN E 276 13.855 27.269 36.326 1.00 15.75 C ANISOU 2073 CD GLN E 276 1968 1979 2035 -29 64 38 C ATOM 2074 OE1 GLN E 276 14.319 26.786 37.362 1.00 19.43 O ANISOU 2074 OE1 GLN E 276 2506 2563 2312 100 -50 39 O ATOM 2075 NE2 GLN E 276 12.577 27.133 35.968 1.00 17.21 N ANISOU 2075 NE2 GLN E 276 2077 2231 2230 -12 -47 -22 N ATOM 2076 N TYR E 277 19.138 28.333 34.279 1.00 8.90 N ANISOU 2076 N TYR E 277 1129 1098 1155 -13 14 -15 N ATOM 2077 CA TYR E 277 20.523 27.958 34.150 1.00 9.70 C ANISOU 2077 CA TYR E 277 1220 1245 1220 0 15 3 C ATOM 2078 C TYR E 277 21.226 28.481 35.388 1.00 9.69 C ANISOU 2078 C TYR E 277 1180 1265 1235 -12 17 15 C ATOM 2079 O TYR E 277 21.107 29.656 35.715 1.00 8.44 O ANISOU 2079 O TYR E 277 991 1181 1031 -45 52 2 O ATOM 2080 CB TYR E 277 21.112 28.596 32.899 1.00 9.77 C ANISOU 2080 CB TYR E 277 1208 1266 1237 -3 1 14 C ATOM 2081 CG TYR E 277 22.555 28.237 32.650 1.00 11.33 C ANISOU 2081 CG TYR E 277 1375 1491 1435 31 24 7 C ATOM 2082 CD1 TYR E 277 22.934 26.923 32.407 1.00 12.63 C ANISOU 2082 CD1 TYR E 277 1601 1582 1616 9 14 -9 C ATOM 2083 CD2 TYR E 277 23.535 29.215 32.651 1.00 12.77 C ANISOU 2083 CD2 TYR E 277 1570 1607 1674 -38 -7 -19 C ATOM 2084 CE1 TYR E 277 24.261 26.597 32.185 1.00 13.82 C ANISOU 2084 CE1 TYR E 277 1732 1758 1758 76 62 -30 C ATOM 2085 CE2 TYR E 277 24.851 28.900 32.416 1.00 14.00 C ANISOU 2085 CE2 TYR E 277 1676 1799 1841 25 -26 -40 C ATOM 2086 CZ TYR E 277 25.208 27.588 32.183 1.00 15.05 C ANISOU 2086 CZ TYR E 277 1877 1844 1997 19 -7 -26 C ATOM 2087 OH TYR E 277 26.535 27.291 31.960 1.00 17.83 O ANISOU 2087 OH TYR E 277 2033 2343 2396 79 101 59 O ATOM 2088 N LEU E 278 21.920 27.603 36.105 1.00 11.40 N ANISOU 2088 N LEU E 278 1409 1456 1463 29 46 41 N ATOM 2089 CA LEU E 278 22.694 28.003 37.273 1.00 12.05 C ANISOU 2089 CA LEU E 278 1497 1535 1544 -4 30 12 C ATOM 2090 C LEU E 278 21.907 28.854 38.276 1.00 11.86 C ANISOU 2090 C LEU E 278 1458 1511 1535 1 47 22 C ATOM 2091 O LEU E 278 22.394 29.886 38.735 1.00 11.41 O ANISOU 2091 O LEU E 278 1294 1497 1543 -20 57 64 O ATOM 2092 CB LEU E 278 23.965 28.746 36.842 1.00 12.80 C ANISOU 2092 CB LEU E 278 1572 1658 1632 -26 28 41 C ATOM 2093 CG LEU E 278 24.825 27.928 35.864 1.00 14.82 C ANISOU 2093 CG LEU E 278 1857 1868 1904 25 52 -24 C ATOM 2094 CD1 LEU E 278 26.021 28.727 35.373 1.00 15.98 C ANISOU 2094 CD1 LEU E 278 1944 2025 2102 -14 67 16 C ATOM 2095 CD2 LEU E 278 25.297 26.642 36.518 1.00 16.59 C ANISOU 2095 CD2 LEU E 278 2124 2040 2138 65 52 56 C ATOM 2096 N SER E 279 20.686 28.410 38.587 1.00 11.12 N ANISOU 2096 N SER E 279 1349 1443 1431 8 18 59 N ATOM 2097 CA SER E 279 19.840 29.044 39.602 1.00 10.76 C ANISOU 2097 CA SER E 279 1325 1347 1415 6 30 44 C ATOM 2098 C SER E 279 19.308 30.419 39.252 1.00 9.09 C ANISOU 2098 C SER E 279 1099 1209 1145 -24 -1 14 C ATOM 2099 O SER E 279 18.877 31.165 40.130 1.00 8.61 O ANISOU 2099 O SER E 279 953 1217 1100 -24 22 101 O ATOM 2100 CB SER E 279 20.559 29.091 40.943 1.00 11.49 C ANISOU 2100 CB SER E 279 1388 1461 1515 14 41 57 C ATOM 2101 OG SER E 279 20.908 27.781 41.352 1.00 14.32 O ANISOU 2101 OG SER E 279 1709 1670 2061 85 131 190 O ATOM 2102 N LYS E 280 19.327 30.757 37.970 1.00 7.65 N ANISOU 2102 N LYS E 280 865 1023 1015 -19 20 44 N ATOM 2103 CA LYS E 280 18.793 32.035 37.539 1.00 7.41 C ANISOU 2103 CA LYS E 280 877 973 965 -15 8 7 C ATOM 2104 C LYS E 280 17.942 31.802 36.306 1.00 6.03 C ANISOU 2104 C LYS E 280 682 777 832 -30 23 -7 C ATOM 2105 O LYS E 280 18.076 30.782 35.647 1.00 6.64 O ANISOU 2105 O LYS E 280 685 922 916 39 -31 -54 O ATOM 2106 CB LYS E 280 19.922 33.021 37.202 1.00 8.38 C ANISOU 2106 CB LYS E 280 1016 1014 1151 -6 85 37 C ATOM 2107 CG LYS E 280 20.722 33.513 38.383 1.00 10.96 C ANISOU 2107 CG LYS E 280 1338 1408 1417 67 -4 21 C ATOM 2108 CD LYS E 280 21.757 34.573 37.971 1.00 13.64 C ANISOU 2108 CD LYS E 280 1753 1645 1781 -42 84 -6 C ATOM 2109 CE LYS E 280 23.014 34.501 38.833 1.00 16.36 C ANISOU 2109 CE LYS E 280 2001 2049 2166 26 -35 14 C ATOM 2110 NZ LYS E 280 24.117 35.430 38.405 1.00 18.65 N ANISOU 2110 NZ LYS E 280 2271 2265 2549 -22 129 91 N ATOM 2111 N THR E 281 17.092 32.767 35.990 1.00 4.84 N ANISOU 2111 N THR E 281 561 642 636 -51 81 21 N ATOM 2112 CA THR E 281 16.272 32.700 34.801 1.00 4.73 C ANISOU 2112 CA THR E 281 567 592 637 -8 62 34 C ATOM 2113 C THR E 281 16.874 33.597 33.747 1.00 4.17 C ANISOU 2113 C THR E 281 466 569 547 -39 50 12 C ATOM 2114 O THR E 281 17.205 34.758 34.015 1.00 4.37 O ANISOU 2114 O THR E 281 536 656 465 1 122 -3 O ATOM 2115 CB THR E 281 14.843 33.154 35.086 1.00 5.12 C ANISOU 2115 CB THR E 281 620 619 705 12 97 64 C ATOM 2116 OG1 THR E 281 14.256 32.284 36.070 1.00 5.21 O ANISOU 2116 OG1 THR E 281 461 801 716 -33 186 159 O ATOM 2117 CG2 THR E 281 13.959 33.065 33.856 1.00 6.11 C ANISOU 2117 CG2 THR E 281 712 765 841 46 105 119 C ATOM 2118 N TYR E 282 17.043 33.025 32.566 1.00 4.91 N ANISOU 2118 N TYR E 282 582 640 642 0 8 33 N ATOM 2119 CA TYR E 282 17.511 33.762 31.401 1.00 5.18 C ANISOU 2119 CA TYR E 282 642 649 677 -24 54 11 C ATOM 2120 C TYR E 282 16.484 33.672 30.304 1.00 5.20 C ANISOU 2120 C TYR E 282 660 638 677 -39 36 17 C ATOM 2121 O TYR E 282 15.508 32.916 30.386 1.00 4.48 O ANISOU 2121 O TYR E 282 502 633 566 -81 58 9 O ATOM 2122 CB TYR E 282 18.847 33.222 30.921 1.00 6.23 C ANISOU 2122 CB TYR E 282 753 828 783 16 40 36 C ATOM 2123 CG TYR E 282 19.925 33.442 31.940 1.00 7.94 C ANISOU 2123 CG TYR E 282 885 1102 1029 -20 -19 -8 C ATOM 2124 CD1 TYR E 282 20.538 34.675 32.084 1.00 9.69 C ANISOU 2124 CD1 TYR E 282 1170 1182 1330 -9 20 14 C ATOM 2125 CD2 TYR E 282 20.286 32.422 32.807 1.00 10.05 C ANISOU 2125 CD2 TYR E 282 1224 1240 1353 26 20 93 C ATOM 2126 CE1 TYR E 282 21.516 34.872 33.056 1.00 11.23 C ANISOU 2126 CE1 TYR E 282 1342 1469 1455 -33 -39 48 C ATOM 2127 CE2 TYR E 282 21.255 32.597 33.748 1.00 11.30 C ANISOU 2127 CE2 TYR E 282 1357 1474 1462 54 -25 39 C ATOM 2128 CZ TYR E 282 21.870 33.823 33.882 1.00 11.89 C ANISOU 2128 CZ TYR E 282 1425 1488 1603 5 22 57 C ATOM 2129 OH TYR E 282 22.840 34.005 34.838 1.00 14.38 O ANISOU 2129 OH TYR E 282 1666 1896 1900 -3 -51 76 O ATOM 2130 N CYS E 283 16.705 34.447 29.259 1.00 5.89 N ANISOU 2130 N CYS E 283 754 786 696 -43 46 34 N ATOM 2131 CA CYS E 283 15.788 34.476 28.152 1.00 6.42 C ANISOU 2131 CA CYS E 283 808 854 774 -19 42 15 C ATOM 2132 C CYS E 283 16.555 34.699 26.869 1.00 6.32 C ANISOU 2132 C CYS E 283 792 842 765 -5 53 1 C ATOM 2133 O CYS E 283 17.439 35.539 26.825 1.00 6.57 O ANISOU 2133 O CYS E 283 858 896 740 -60 76 -71 O ATOM 2134 CB CYS E 283 14.817 35.633 28.337 1.00 7.06 C ANISOU 2134 CB CYS E 283 902 885 892 -31 90 2 C ATOM 2135 SG CYS E 283 13.590 35.795 27.049 1.00 11.48 S ANISOU 2135 SG CYS E 283 1409 1490 1461 178 -144 -85 S ATOM 2136 N VAL E 284 16.234 33.924 25.848 1.00 6.46 N ANISOU 2136 N VAL E 284 837 835 782 -15 16 11 N ATOM 2137 CA VAL E 284 16.758 34.196 24.518 1.00 6.88 C ANISOU 2137 CA VAL E 284 899 911 801 29 44 7 C ATOM 2138 C VAL E 284 15.692 35.038 23.816 1.00 6.55 C ANISOU 2138 C VAL E 284 861 917 709 -2 9 -15 C ATOM 2139 O VAL E 284 14.599 34.566 23.540 1.00 7.41 O ANISOU 2139 O VAL E 284 920 1047 846 -23 -14 104 O ATOM 2140 CB VAL E 284 17.019 32.939 23.677 1.00 6.98 C ANISOU 2140 CB VAL E 284 964 932 753 -6 8 -33 C ATOM 2141 CG1 VAL E 284 17.524 33.347 22.297 1.00 7.25 C ANISOU 2141 CG1 VAL E 284 981 954 817 53 86 8 C ATOM 2142 CG2 VAL E 284 18.050 32.046 24.310 1.00 8.15 C ANISOU 2142 CG2 VAL E 284 1121 1116 860 81 72 43 C ATOM 2143 N ASP E 285 16.010 36.290 23.552 1.00 7.17 N ANISOU 2143 N ASP E 285 907 993 824 35 36 -2 N ATOM 2144 CA ASP E 285 15.080 37.189 22.889 1.00 7.47 C ANISOU 2144 CA ASP E 285 958 986 894 14 -3 5 C ATOM 2145 C ASP E 285 15.390 37.160 21.393 1.00 7.41 C ANISOU 2145 C ASP E 285 960 974 880 -13 -15 -10 C ATOM 2146 O ASP E 285 16.419 37.673 20.969 1.00 8.42 O ANISOU 2146 O ASP E 285 1103 1089 1005 41 31 3 O ATOM 2147 CB ASP E 285 15.274 38.594 23.448 1.00 7.84 C ANISOU 2147 CB ASP E 285 1022 1041 912 41 -25 -25 C ATOM 2148 CG ASP E 285 14.398 39.626 22.785 1.00 8.62 C ANISOU 2148 CG ASP E 285 1106 1101 1068 31 -42 -25 C ATOM 2149 OD1 ASP E 285 13.641 39.287 21.854 1.00 10.29 O ANISOU 2149 OD1 ASP E 285 1220 1517 1172 85 -177 -170 O ATOM 2150 OD2 ASP E 285 14.411 40.816 23.145 1.00 9.22 O ANISOU 2150 OD2 ASP E 285 1255 1164 1084 55 -98 -181 O ATOM 2151 N ALA E 286 14.514 36.527 20.610 1.00 7.69 N ANISOU 2151 N ALA E 286 995 1014 913 -2 -23 -34 N ATOM 2152 CA ALA E 286 14.724 36.406 19.163 1.00 7.78 C ANISOU 2152 CA ALA E 286 992 1025 935 0 -5 -3 C ATOM 2153 C ALA E 286 13.741 37.284 18.398 1.00 7.95 C ANISOU 2153 C ALA E 286 988 1062 968 -7 -12 -6 C ATOM 2154 O ALA E 286 13.328 36.967 17.283 1.00 8.52 O ANISOU 2154 O ALA E 286 1105 1141 991 27 -52 -72 O ATOM 2155 CB ALA E 286 14.605 34.950 18.736 1.00 7.45 C ANISOU 2155 CB ALA E 286 931 1020 879 1 -34 16 C ATOM 2156 N THR E 287 13.365 38.398 18.999 1.00 8.56 N ANISOU 2156 N THR E 287 1079 1123 1048 -25 -14 -9 N ATOM 2157 CA THR E 287 12.360 39.267 18.407 1.00 9.78 C ANISOU 2157 CA THR E 287 1228 1271 1216 5 3 15 C ATOM 2158 C THR E 287 12.801 39.913 17.103 1.00 10.21 C ANISOU 2158 C THR E 287 1292 1344 1240 32 -15 -9 C ATOM 2159 O THR E 287 12.006 40.095 16.178 1.00 10.38 O ANISOU 2159 O THR E 287 1313 1505 1124 64 -51 -41 O ATOM 2160 CB THR E 287 12.001 40.371 19.393 1.00 9.95 C ANISOU 2160 CB THR E 287 1270 1268 1240 10 -18 -6 C ATOM 2161 OG1 THR E 287 10.844 41.078 18.922 1.00 12.79 O ANISOU 2161 OG1 THR E 287 1487 1726 1644 78 13 88 O ATOM 2162 CG2 THR E 287 13.076 41.405 19.418 1.00 11.93 C ANISOU 2162 CG2 THR E 287 1466 1497 1569 4 -3 -29 C ATOM 2163 N ARG E 288 14.063 40.291 17.034 1.00 10.65 N ANISOU 2163 N ARG E 288 1319 1386 1342 -1 2 7 N ATOM 2164 CA ARG E 288 14.526 40.974 15.853 1.00 11.77 C ANISOU 2164 CA ARG E 288 1499 1502 1472 8 0 17 C ATOM 2165 C ARG E 288 14.536 40.055 14.644 1.00 11.86 C ANISOU 2165 C ARG E 288 1494 1514 1496 -5 4 16 C ATOM 2166 O ARG E 288 14.933 38.890 14.744 1.00 11.45 O ANISOU 2166 O ARG E 288 1430 1505 1416 42 15 -38 O ATOM 2167 CB ARG E 288 15.916 41.539 16.083 1.00 12.43 C ANISOU 2167 CB ARG E 288 1547 1597 1575 -2 2 -24 C ATOM 2168 CG ARG E 288 16.246 42.599 15.083 1.00 14.76 C ANISOU 2168 CG ARG E 288 1964 1863 1779 -5 -7 43 C ATOM 2169 CD ARG E 288 17.613 42.457 14.500 1.00 18.60 C ANISOU 2169 CD ARG E 288 2274 2428 2364 55 80 -31 C ATOM 2170 NE ARG E 288 18.638 42.603 15.513 1.00 21.53 N ANISOU 2170 NE ARG E 288 2696 2786 2696 -8 -67 -49 N ATOM 2171 CZ ARG E 288 19.931 42.480 15.279 1.00 23.97 C ANISOU 2171 CZ ARG E 288 2906 3148 3050 49 32 -25 C ATOM 2172 NH1 ARG E 288 20.365 42.188 14.054 1.00 23.91 N ANISOU 2172 NH1 ARG E 288 3035 3096 2952 28 -28 -28 N ATOM 2173 NH2 ARG E 288 20.792 42.653 16.279 1.00 25.58 N ANISOU 2173 NH2 ARG E 288 3222 3319 3179 58 -67 -54 N ATOM 2174 N GLU E 289 14.073 40.574 13.505 1.00 12.86 N ANISOU 2174 N GLU E 289 1627 1654 1606 22 -2 16 N ATOM 2175 CA GLU E 289 14.088 39.787 12.282 1.00 13.33 C ANISOU 2175 CA GLU E 289 1687 1717 1661 15 -10 -4 C ATOM 2176 C GLU E 289 15.530 39.616 11.840 1.00 13.62 C ANISOU 2176 C GLU E 289 1717 1731 1725 1 2 2 C ATOM 2177 O GLU E 289 16.254 40.592 11.643 1.00 14.21 O ANISOU 2177 O GLU E 289 1759 1812 1826 0 26 10 O ATOM 2178 CB GLU E 289 13.275 40.445 11.167 1.00 13.83 C ANISOU 2178 CB GLU E 289 1743 1777 1733 25 -12 24 C ATOM 2179 CG GLU E 289 11.766 40.321 11.367 1.00 14.55 C ANISOU 2179 CG GLU E 289 1778 1897 1850 22 -12 4 C ATOM 2180 CD GLU E 289 11.215 38.901 11.249 1.00 15.49 C ANISOU 2180 CD GLU E 289 1989 1964 1931 23 -22 6 C ATOM 2181 OE1 GLU E 289 11.675 38.119 10.385 1.00 15.06 O ANISOU 2181 OE1 GLU E 289 1936 1861 1923 3 -154 -39 O ATOM 2182 OE2 GLU E 289 10.292 38.561 12.027 1.00 16.93 O ANISOU 2182 OE2 GLU E 289 2026 2231 2173 22 -57 -36 O ATOM 2183 N THR E 290 15.938 38.361 11.724 1.00 13.76 N ANISOU 2183 N THR E 290 1768 1733 1726 18 14 -11 N ATOM 2184 CA THR E 290 17.268 38.000 11.273 1.00 13.61 C ANISOU 2184 CA THR E 290 1725 1735 1709 2 -15 -10 C ATOM 2185 C THR E 290 17.139 36.854 10.269 1.00 13.70 C ANISOU 2185 C THR E 290 1763 1734 1707 -5 -17 -6 C ATOM 2186 O THR E 290 16.034 36.469 9.893 1.00 14.53 O ANISOU 2186 O THR E 290 1868 1860 1790 28 -84 -58 O ATOM 2187 CB THR E 290 18.114 37.508 12.454 1.00 13.76 C ANISOU 2187 CB THR E 290 1771 1759 1696 3 -11 -21 C ATOM 2188 OG1 THR E 290 17.597 36.259 12.932 1.00 12.56 O ANISOU 2188 OG1 THR E 290 1588 1723 1460 48 -11 -53 O ATOM 2189 CG2 THR E 290 18.030 38.462 13.649 1.00 14.08 C ANISOU 2189 CG2 THR E 290 1818 1807 1725 57 -5 -48 C ATOM 2190 N ASN E 291 18.271 36.278 9.890 1.00 13.79 N ANISOU 2190 N ASN E 291 1794 1732 1712 -9 -11 -11 N ATOM 2191 CA ASN E 291 18.316 35.154 8.959 1.00 14.19 C ANISOU 2191 CA ASN E 291 1846 1783 1763 5 -16 -11 C ATOM 2192 C ASN E 291 18.188 33.791 9.603 1.00 13.87 C ANISOU 2192 C ASN E 291 1801 1746 1722 4 -16 -29 C ATOM 2193 O ASN E 291 18.099 32.769 8.913 1.00 14.55 O ANISOU 2193 O ASN E 291 1953 1773 1801 26 -44 -7 O ATOM 2194 CB ASN E 291 19.668 35.176 8.266 1.00 14.90 C ANISOU 2194 CB ASN E 291 1882 1877 1900 21 17 -11 C ATOM 2195 CG ASN E 291 20.835 35.107 9.268 1.00 15.38 C ANISOU 2195 CG ASN E 291 1955 1946 1941 6 -32 -1 C ATOM 2196 OD1 ASN E 291 21.012 36.004 10.105 1.00 15.91 O ANISOU 2196 OD1 ASN E 291 1961 2090 1994 17 -6 -3 O ATOM 2197 ND2 ASN E 291 21.627 34.046 9.185 1.00 16.18 N ANISOU 2197 ND2 ASN E 291 2034 1958 2156 42 -21 -11 N ATOM 2198 N ARG E 292 18.177 33.785 10.928 1.00 13.33 N ANISOU 2198 N ARG E 292 1748 1664 1651 6 10 18 N ATOM 2199 CA ARG E 292 18.186 32.556 11.704 1.00 13.08 C ANISOU 2199 CA ARG E 292 1668 1632 1668 2 16 12 C ATOM 2200 C ARG E 292 16.826 31.891 11.653 1.00 12.35 C ANISOU 2200 C ARG E 292 1581 1522 1589 16 5 -1 C ATOM 2201 O ARG E 292 15.807 32.554 11.804 1.00 12.82 O ANISOU 2201 O ARG E 292 1592 1625 1654 50 84 24 O ATOM 2202 CB ARG E 292 18.577 32.875 13.141 1.00 13.53 C ANISOU 2202 CB ARG E 292 1714 1687 1738 8 -19 -3 C ATOM 2203 CG ARG E 292 19.970 33.443 13.252 1.00 15.02 C ANISOU 2203 CG ARG E 292 1904 1897 1903 -53 -24 38 C ATOM 2204 CD ARG E 292 21.027 32.552 12.649 1.00 17.68 C ANISOU 2204 CD ARG E 292 2224 2177 2313 27 7 -49 C ATOM 2205 NE ARG E 292 22.330 32.784 13.254 1.00 20.87 N ANISOU 2205 NE ARG E 292 2570 2628 2730 0 -103 -28 N ATOM 2206 CZ ARG E 292 23.009 31.880 13.956 1.00 21.97 C ANISOU 2206 CZ ARG E 292 2775 2734 2836 38 -47 38 C ATOM 2207 NH1 ARG E 292 22.525 30.655 14.145 1.00 21.45 N ANISOU 2207 NH1 ARG E 292 2691 2694 2763 -3 -18 -18 N ATOM 2208 NH2 ARG E 292 24.187 32.208 14.466 1.00 23.17 N ANISOU 2208 NH2 ARG E 292 2888 2910 3003 1 -96 -23 N ATOM 2209 N LEU E 293 16.811 30.575 11.458 1.00 10.81 N ANISOU 2209 N LEU E 293 1377 1362 1368 -21 7 14 N ATOM 2210 CA LEU E 293 15.558 29.853 11.271 1.00 10.26 C ANISOU 2210 CA LEU E 293 1292 1320 1286 -21 7 2 C ATOM 2211 C LEU E 293 14.883 29.338 12.534 1.00 8.82 C ANISOU 2211 C LEU E 293 1064 1118 1165 -8 -9 -13 C ATOM 2212 O LEU E 293 13.696 29.048 12.510 1.00 7.84 O ANISOU 2212 O LEU E 293 872 1031 1074 -97 -67 -46 O ATOM 2213 CB LEU E 293 15.804 28.658 10.356 1.00 11.44 C ANISOU 2213 CB LEU E 293 1531 1359 1455 4 38 9 C ATOM 2214 CG LEU E 293 16.258 29.011 8.946 1.00 13.07 C ANISOU 2214 CG LEU E 293 1672 1672 1622 21 56 -11 C ATOM 2215 CD1 LEU E 293 16.322 27.760 8.084 1.00 14.31 C ANISOU 2215 CD1 LEU E 293 1956 1779 1700 13 43 -59 C ATOM 2216 CD2 LEU E 293 15.310 30.018 8.328 1.00 14.25 C ANISOU 2216 CD2 LEU E 293 1811 1819 1784 39 21 65 C ATOM 2217 N GLY E 294 15.620 29.167 13.626 1.00 8.18 N ANISOU 2217 N GLY E 294 1005 1024 1077 -59 -35 -61 N ATOM 2218 CA GLY E 294 15.039 28.605 14.828 1.00 8.11 C ANISOU 2218 CA GLY E 294 964 1016 1101 26 -34 -27 C ATOM 2219 C GLY E 294 13.811 29.362 15.317 1.00 7.18 C ANISOU 2219 C GLY E 294 908 926 893 -7 46 -33 C ATOM 2220 O GLY E 294 12.823 28.772 15.733 1.00 7.26 O ANISOU 2220 O GLY E 294 862 958 935 -35 12 -14 O ATOM 2221 N ARG E 295 13.885 30.686 15.234 1.00 6.97 N ANISOU 2221 N ARG E 295 854 891 900 -16 47 31 N ATOM 2222 CA ARG E 295 12.828 31.573 15.710 1.00 6.63 C ANISOU 2222 CA ARG E 295 870 813 833 -20 7 -8 C ATOM 2223 C ARG E 295 11.536 31.471 14.883 1.00 7.26 C ANISOU 2223 C ARG E 295 876 936 943 20 1 -1 C ATOM 2224 O ARG E 295 10.497 31.998 15.290 1.00 8.13 O ANISOU 2224 O ARG E 295 1044 1008 1037 24 10 -33 O ATOM 2225 CB ARG E 295 13.352 33.022 15.699 1.00 6.87 C ANISOU 2225 CB ARG E 295 833 851 923 -73 6 32 C ATOM 2226 CG ARG E 295 13.735 33.516 14.319 1.00 6.84 C ANISOU 2226 CG ARG E 295 856 860 880 20 31 -80 C ATOM 2227 CD ARG E 295 14.376 34.886 14.309 1.00 6.96 C ANISOU 2227 CD ARG E 295 821 938 886 22 -99 -133 C ATOM 2228 NE ARG E 295 13.442 35.938 14.720 1.00 6.37 N ANISOU 2228 NE ARG E 295 752 853 815 30 -109 -75 N ATOM 2229 CZ ARG E 295 12.632 36.575 13.899 1.00 6.78 C ANISOU 2229 CZ ARG E 295 892 817 866 -29 -54 -3 C ATOM 2230 NH1 ARG E 295 12.611 36.270 12.612 1.00 7.14 N ANISOU 2230 NH1 ARG E 295 865 1034 814 61 -13 -57 N ATOM 2231 NH2 ARG E 295 11.828 37.514 14.370 1.00 9.08 N ANISOU 2231 NH2 ARG E 295 1103 1159 1186 89 14 -23 N ATOM 2232 N LEU E 296 11.599 30.803 13.731 1.00 7.05 N ANISOU 2232 N LEU E 296 866 864 947 26 -55 11 N ATOM 2233 CA LEU E 296 10.427 30.672 12.859 1.00 7.11 C ANISOU 2233 CA LEU E 296 905 882 912 6 -42 5 C ATOM 2234 C LEU E 296 9.739 29.337 12.976 1.00 7.00 C ANISOU 2234 C LEU E 296 837 939 883 -9 -45 -14 C ATOM 2235 O LEU E 296 8.738 29.094 12.281 1.00 8.35 O ANISOU 2235 O LEU E 296 874 1104 1192 -47 -192 -11 O ATOM 2236 CB LEU E 296 10.826 30.876 11.390 1.00 7.24 C ANISOU 2236 CB LEU E 296 942 946 862 -12 -51 2 C ATOM 2237 CG LEU E 296 11.416 32.250 11.045 1.00 7.38 C ANISOU 2237 CG LEU E 296 815 993 995 -59 -27 5 C ATOM 2238 CD1 LEU E 296 11.707 32.391 9.560 1.00 8.27 C ANISOU 2238 CD1 LEU E 296 981 1044 1116 1 -27 89 C ATOM 2239 CD2 LEU E 296 10.489 33.396 11.496 1.00 8.04 C ANISOU 2239 CD2 LEU E 296 1057 1003 995 31 11 35 C ATOM 2240 N ILE E 297 10.267 28.460 13.814 1.00 6.33 N ANISOU 2240 N ILE E 297 722 878 803 30 21 -2 N ATOM 2241 CA ILE E 297 9.672 27.143 13.986 1.00 6.02 C ANISOU 2241 CA ILE E 297 780 816 689 0 -32 -44 C ATOM 2242 C ILE E 297 8.406 27.228 14.848 1.00 6.04 C ANISOU 2242 C ILE E 297 757 786 750 1 -16 -22 C ATOM 2243 O ILE E 297 8.389 27.870 15.908 1.00 6.69 O ANISOU 2243 O ILE E 297 754 917 870 -2 -77 -68 O ATOM 2244 CB ILE E 297 10.693 26.167 14.570 1.00 6.85 C ANISOU 2244 CB ILE E 297 915 864 822 9 -9 -6 C ATOM 2245 CG1 ILE E 297 11.829 25.974 13.561 1.00 8.62 C ANISOU 2245 CG1 ILE E 297 1089 1071 1113 -1 21 9 C ATOM 2246 CG2 ILE E 297 10.030 24.841 14.903 1.00 7.32 C ANISOU 2246 CG2 ILE E 297 960 916 902 72 80 11 C ATOM 2247 CD1 ILE E 297 12.953 25.156 14.063 1.00 9.96 C ANISOU 2247 CD1 ILE E 297 1206 1079 1498 -28 -38 20 C ATOM 2248 N ASN E 298 7.340 26.593 14.370 1.00 6.14 N ANISOU 2248 N ASN E 298 818 762 751 -45 -37 -34 N ATOM 2249 CA ASN E 298 6.045 26.591 15.048 1.00 5.78 C ANISOU 2249 CA ASN E 298 803 710 684 0 -11 -24 C ATOM 2250 C ASN E 298 5.897 25.555 16.165 1.00 5.19 C ANISOU 2250 C ASN E 298 685 569 718 -19 -29 -48 C ATOM 2251 O ASN E 298 6.775 24.732 16.382 1.00 4.75 O ANISOU 2251 O ASN E 298 625 559 618 -80 -22 -95 O ATOM 2252 CB ASN E 298 4.925 26.500 14.039 1.00 6.29 C ANISOU 2252 CB ASN E 298 809 787 792 -40 17 39 C ATOM 2253 CG ASN E 298 4.874 27.729 13.163 1.00 7.64 C ANISOU 2253 CG ASN E 298 1000 939 960 95 -88 58 C ATOM 2254 OD1 ASN E 298 4.898 28.850 13.683 1.00 8.74 O ANISOU 2254 OD1 ASN E 298 1228 967 1125 -16 -166 31 O ATOM 2255 ND2 ASN E 298 4.822 27.540 11.844 1.00 9.26 N ANISOU 2255 ND2 ASN E 298 1240 1254 1023 141 -49 -32 N ATOM 2256 N HIS E 299 4.780 25.662 16.882 1.00 5.83 N ANISOU 2256 N HIS E 299 814 701 698 -62 39 29 N ATOM 2257 CA HIS E 299 4.495 24.869 18.074 1.00 5.92 C ANISOU 2257 CA HIS E 299 770 723 755 14 45 -2 C ATOM 2258 C HIS E 299 3.651 23.645 17.819 1.00 5.85 C ANISOU 2258 C HIS E 299 768 765 687 -6 -12 -46 C ATOM 2259 O HIS E 299 2.690 23.713 17.077 1.00 6.86 O ANISOU 2259 O HIS E 299 938 767 899 77 -84 -48 O ATOM 2260 CB HIS E 299 3.753 25.761 19.084 1.00 5.68 C ANISOU 2260 CB HIS E 299 777 691 690 -30 -7 -11 C ATOM 2261 CG HIS E 299 3.108 25.016 20.208 1.00 5.90 C ANISOU 2261 CG HIS E 299 805 655 779 -6 12 -68 C ATOM 2262 ND1 HIS E 299 3.780 24.674 21.363 1.00 6.25 N ANISOU 2262 ND1 HIS E 299 952 681 742 25 32 -21 N ATOM 2263 CD2 HIS E 299 1.842 24.551 20.356 1.00 5.64 C ANISOU 2263 CD2 HIS E 299 736 698 707 41 14 -69 C ATOM 2264 CE1 HIS E 299 2.957 24.016 22.165 1.00 6.61 C ANISOU 2264 CE1 HIS E 299 912 790 809 35 75 -126 C ATOM 2265 NE2 HIS E 299 1.779 23.920 21.575 1.00 7.87 N ANISOU 2265 NE2 HIS E 299 1051 978 958 101 15 61 N ATOM 2266 N SER E 300 3.987 22.556 18.504 1.00 6.26 N ANISOU 2266 N SER E 300 813 761 805 -12 -54 -44 N ATOM 2267 CA SER E 300 3.103 21.408 18.690 1.00 7.35 C ANISOU 2267 CA SER E 300 925 943 922 -31 1 2 C ATOM 2268 C SER E 300 3.480 20.714 19.991 1.00 8.31 C ANISOU 2268 C SER E 300 1079 1025 1052 -31 -62 0 C ATOM 2269 O SER E 300 4.662 20.631 20.307 1.00 8.53 O ANISOU 2269 O SER E 300 1148 1001 1089 -16 -102 149 O ATOM 2270 CB SER E 300 3.241 20.370 17.595 1.00 8.23 C ANISOU 2270 CB SER E 300 1065 1019 1042 -16 -44 -45 C ATOM 2271 OG SER E 300 2.267 19.356 17.780 1.00 9.98 O ANISOU 2271 OG SER E 300 1364 1142 1282 -83 -7 -54 O ATOM 2272 N LYS E 301 2.488 20.205 20.716 1.00 10.30 N ANISOU 2272 N LYS E 301 1318 1305 1289 31 25 28 N ATOM 2273 CA LYS E 301 2.775 19.370 21.878 1.00 12.12 C ANISOU 2273 CA LYS E 301 1593 1561 1450 11 19 42 C ATOM 2274 C LYS E 301 3.142 17.946 21.433 1.00 13.80 C ANISOU 2274 C LYS E 301 1844 1732 1668 62 17 47 C ATOM 2275 O LYS E 301 3.614 17.151 22.243 1.00 16.14 O ANISOU 2275 O LYS E 301 2208 1960 1963 219 -38 86 O ATOM 2276 CB LYS E 301 1.611 19.369 22.878 1.00 12.73 C ANISOU 2276 CB LYS E 301 1649 1661 1526 3 53 68 C ATOM 2277 CG LYS E 301 1.502 20.677 23.683 1.00 15.45 C ANISOU 2277 CG LYS E 301 2065 1836 1969 -15 -30 -6 C ATOM 2278 CD LYS E 301 0.525 20.594 24.843 1.00 18.63 C ANISOU 2278 CD LYS E 301 2403 2337 2336 36 63 -20 C ATOM 2279 CE LYS E 301 -0.877 20.318 24.376 1.00 21.08 C ANISOU 2279 CE LYS E 301 2657 2657 2695 18 -17 14 C ATOM 2280 NZ LYS E 301 -1.900 20.719 25.382 1.00 22.61 N ANISOU 2280 NZ LYS E 301 2800 2884 2905 33 89 0 N ATOM 2281 N CYS E 302 2.933 17.614 20.158 1.00 14.19 N ANISOU 2281 N CYS E 302 1849 1844 1698 39 37 23 N ATOM 2282 CA CYS E 302 3.341 16.306 19.630 1.00 15.39 C ANISOU 2282 CA CYS E 302 1996 1952 1900 22 42 10 C ATOM 2283 C CYS E 302 4.128 16.544 18.350 1.00 14.11 C ANISOU 2283 C CYS E 302 1820 1791 1747 16 16 -24 C ATOM 2284 O CYS E 302 3.773 16.075 17.263 1.00 15.53 O ANISOU 2284 O CYS E 302 1917 2046 1936 97 -60 -41 O ATOM 2285 CB CYS E 302 2.157 15.412 19.341 1.00 17.02 C ANISOU 2285 CB CYS E 302 2233 2134 2100 -11 59 -79 C ATOM 2286 SG CYS E 302 0.901 16.249 18.421 1.00 23.76 S ANISOU 2286 SG CYS E 302 3190 2862 2975 186 -150 -10 S ATOM 2287 N GLY E 303 5.207 17.285 18.515 1.00 12.95 N ANISOU 2287 N GLY E 303 1588 1715 1615 29 45 51 N ATOM 2288 CA GLY E 303 6.071 17.676 17.418 1.00 11.46 C ANISOU 2288 CA GLY E 303 1454 1451 1448 33 50 23 C ATOM 2289 C GLY E 303 7.146 16.663 17.111 1.00 11.25 C ANISOU 2289 C GLY E 303 1405 1350 1520 7 99 73 C ATOM 2290 O GLY E 303 7.028 15.470 17.411 1.00 13.15 O ANISOU 2290 O GLY E 303 1564 1459 1970 86 88 128 O ATOM 2291 N ASN E 304 8.198 17.142 16.472 1.00 8.37 N ANISOU 2291 N ASN E 304 1084 996 1099 -15 32 -2 N ATOM 2292 CA ASN E 304 9.271 16.266 16.056 1.00 8.23 C ANISOU 2292 CA ASN E 304 1073 982 1069 16 16 17 C ATOM 2293 C ASN E 304 10.640 16.737 16.504 1.00 8.20 C ANISOU 2293 C ASN E 304 1034 1064 1016 30 1 -43 C ATOM 2294 O ASN E 304 11.648 16.085 16.210 1.00 9.09 O ANISOU 2294 O ASN E 304 1103 1231 1118 91 -115 -192 O ATOM 2295 CB ASN E 304 9.204 16.063 14.544 1.00 7.44 C ANISOU 2295 CB ASN E 304 954 879 993 52 -88 -49 C ATOM 2296 CG ASN E 304 9.118 17.371 13.787 1.00 8.32 C ANISOU 2296 CG ASN E 304 1147 974 1040 -73 -20 -27 C ATOM 2297 OD1 ASN E 304 9.634 18.407 14.239 1.00 7.18 O ANISOU 2297 OD1 ASN E 304 948 858 919 11 -49 -44 O ATOM 2298 ND2 ASN E 304 8.490 17.328 12.603 1.00 9.45 N ANISOU 2298 ND2 ASN E 304 1281 1151 1159 21 -100 137 N ATOM 2299 N CYS E 305 10.670 17.829 17.273 1.00 8.75 N ANISOU 2299 N CYS E 305 1054 1128 1142 42 -22 -84 N ATOM 2300 CA CYS E 305 11.897 18.381 17.845 1.00 8.97 C ANISOU 2300 CA CYS E 305 1088 1181 1137 1 -3 -61 C ATOM 2301 C CYS E 305 11.708 18.616 19.336 1.00 8.69 C ANISOU 2301 C CYS E 305 1051 1131 1117 -15 0 -48 C ATOM 2302 O CYS E 305 10.579 18.767 19.814 1.00 8.77 O ANISOU 2302 O CYS E 305 1020 1236 1075 40 3 -110 O ATOM 2303 CB CYS E 305 12.271 19.711 17.196 1.00 9.52 C ANISOU 2303 CB CYS E 305 1135 1205 1277 -46 -43 -81 C ATOM 2304 SG CYS E 305 12.731 19.599 15.472 1.00 11.98 S ANISOU 2304 SG CYS E 305 1305 1814 1432 67 23 -69 S ATOM 2305 N GLN E 306 12.822 18.634 20.059 1.00 8.96 N ANISOU 2305 N GLN E 306 1091 1157 1153 -48 -28 -92 N ATOM 2306 CA GLN E 306 12.849 18.858 21.500 1.00 9.57 C ANISOU 2306 CA GLN E 306 1223 1212 1201 -41 -9 -70 C ATOM 2307 C GLN E 306 13.939 19.887 21.770 1.00 8.68 C ANISOU 2307 C GLN E 306 1074 1105 1119 -26 19 -41 C ATOM 2308 O GLN E 306 15.023 19.800 21.216 1.00 9.23 O ANISOU 2308 O GLN E 306 1222 1050 1235 -60 31 -122 O ATOM 2309 CB GLN E 306 13.206 17.569 22.229 1.00 10.93 C ANISOU 2309 CB GLN E 306 1395 1345 1410 -54 -43 -18 C ATOM 2310 CG GLN E 306 13.224 17.633 23.734 1.00 14.89 C ANISOU 2310 CG GLN E 306 1893 1974 1790 -40 -18 -64 C ATOM 2311 CD GLN E 306 13.373 16.248 24.350 1.00 20.70 C ANISOU 2311 CD GLN E 306 2734 2426 2705 37 10 122 C ATOM 2312 OE1 GLN E 306 14.374 15.568 24.113 1.00 24.59 O ANISOU 2312 OE1 GLN E 306 2995 3062 3285 152 137 27 O ATOM 2313 NE2 GLN E 306 12.374 15.818 25.121 1.00 23.61 N ANISOU 2313 NE2 GLN E 306 2872 3006 3090 -11 133 8 N ATOM 2314 N THR E 307 13.647 20.852 22.636 1.00 8.34 N ANISOU 2314 N THR E 307 1027 1057 1082 -41 -14 -78 N ATOM 2315 CA THR E 307 14.632 21.852 23.006 1.00 8.58 C ANISOU 2315 CA THR E 307 1090 1066 1102 16 -29 -48 C ATOM 2316 C THR E 307 15.475 21.324 24.143 1.00 8.48 C ANISOU 2316 C THR E 307 1140 1012 1068 1 6 -38 C ATOM 2317 O THR E 307 14.953 20.707 25.088 1.00 8.96 O ANISOU 2317 O THR E 307 1248 1150 1003 14 31 -47 O ATOM 2318 CB THR E 307 13.947 23.145 23.443 1.00 9.30 C ANISOU 2318 CB THR E 307 1189 1108 1235 16 -43 -80 C ATOM 2319 OG1 THR E 307 13.064 23.589 22.401 1.00 11.99 O ANISOU 2319 OG1 THR E 307 1594 1441 1517 154 -142 -147 O ATOM 2320 CG2 THR E 307 14.974 24.280 23.648 1.00 9.30 C ANISOU 2320 CG2 THR E 307 1145 1203 1183 -6 9 -8 C ATOM 2321 N LYS E 308 16.772 21.564 24.023 1.00 8.57 N ANISOU 2321 N LYS E 308 1142 1086 1028 -34 19 -18 N ATOM 2322 CA LYS E 308 17.751 21.169 25.023 1.00 9.63 C ANISOU 2322 CA LYS E 308 1194 1218 1244 -14 -8 -28 C ATOM 2323 C LYS E 308 18.611 22.371 25.379 1.00 9.25 C ANISOU 2323 C LYS E 308 1221 1153 1140 -23 -3 -5 C ATOM 2324 O LYS E 308 18.878 23.229 24.538 1.00 9.41 O ANISOU 2324 O LYS E 308 1356 1163 1055 -49 20 -66 O ATOM 2325 CB LYS E 308 18.670 20.079 24.465 1.00 10.34 C ANISOU 2325 CB LYS E 308 1318 1311 1298 22 -15 -20 C ATOM 2326 CG LYS E 308 17.929 18.852 23.971 1.00 13.21 C ANISOU 2326 CG LYS E 308 1681 1577 1760 -17 -41 -86 C ATOM 2327 CD LYS E 308 17.375 18.083 25.140 1.00 16.93 C ANISOU 2327 CD LYS E 308 2145 2192 2094 -54 64 43 C ATOM 2328 CE LYS E 308 17.079 16.644 24.791 1.00 20.05 C ANISOU 2328 CE LYS E 308 2589 2397 2632 33 36 -14 C ATOM 2329 NZ LYS E 308 16.661 15.877 26.006 1.00 21.80 N ANISOU 2329 NZ LYS E 308 2808 2788 2688 33 107 35 N ATOM 2330 N LEU E 309 19.047 22.420 26.626 1.00 9.41 N ANISOU 2330 N LEU E 309 1243 1195 1136 -34 27 -4 N ATOM 2331 CA LEU E 309 20.003 23.417 27.050 1.00 9.75 C ANISOU 2331 CA LEU E 309 1257 1253 1194 -20 17 1 C ATOM 2332 C LEU E 309 21.379 22.807 26.800 1.00 10.54 C ANISOU 2332 C LEU E 309 1337 1326 1339 13 12 33 C ATOM 2333 O LEU E 309 21.685 21.730 27.316 1.00 11.24 O ANISOU 2333 O LEU E 309 1360 1325 1583 -25 171 93 O ATOM 2334 CB LEU E 309 19.784 23.743 28.527 1.00 10.06 C ANISOU 2334 CB LEU E 309 1305 1302 1214 25 20 -6 C ATOM 2335 CG LEU E 309 20.749 24.722 29.174 1.00 11.85 C ANISOU 2335 CG LEU E 309 1510 1530 1459 -28 -38 -16 C ATOM 2336 CD1 LEU E 309 20.788 26.014 28.433 1.00 13.71 C ANISOU 2336 CD1 LEU E 309 1774 1683 1751 62 23 42 C ATOM 2337 CD2 LEU E 309 20.349 24.992 30.620 1.00 13.49 C ANISOU 2337 CD2 LEU E 309 1722 1781 1620 20 74 -29 C ATOM 2338 N HIS E 310 22.196 23.484 25.988 1.00 11.42 N ANISOU 2338 N HIS E 310 1474 1380 1485 0 25 18 N ATOM 2339 CA HIS E 310 23.535 23.029 25.660 1.00 12.11 C ANISOU 2339 CA HIS E 310 1510 1506 1585 -16 -2 8 C ATOM 2340 C HIS E 310 24.514 24.117 26.031 1.00 13.19 C ANISOU 2340 C HIS E 310 1623 1642 1744 -9 13 31 C ATOM 2341 O HIS E 310 24.567 25.142 25.381 1.00 14.02 O ANISOU 2341 O HIS E 310 1716 1735 1875 13 6 65 O ATOM 2342 CB HIS E 310 23.675 22.744 24.162 1.00 12.38 C ANISOU 2342 CB HIS E 310 1538 1519 1645 -24 -20 -4 C ATOM 2343 CG HIS E 310 24.947 22.041 23.815 1.00 13.60 C ANISOU 2343 CG HIS E 310 1712 1673 1780 13 44 -13 C ATOM 2344 ND1 HIS E 310 25.068 20.670 23.863 1.00 14.99 N ANISOU 2344 ND1 HIS E 310 1973 1780 1941 37 47 30 N ATOM 2345 CD2 HIS E 310 26.166 22.514 23.460 1.00 14.05 C ANISOU 2345 CD2 HIS E 310 1739 1782 1817 31 -18 39 C ATOM 2346 CE1 HIS E 310 26.301 20.327 23.536 1.00 13.99 C ANISOU 2346 CE1 HIS E 310 1780 1764 1771 5 -30 32 C ATOM 2347 NE2 HIS E 310 26.986 21.426 23.280 1.00 14.33 N ANISOU 2347 NE2 HIS E 310 1823 1788 1835 3 28 -19 N ATOM 2348 N ASP E 311 25.305 23.901 27.066 1.00 13.92 N ANISOU 2348 N ASP E 311 1764 1781 1745 -35 -6 -3 N ATOM 2349 CA ASP E 311 26.241 24.937 27.476 1.00 15.06 C ANISOU 2349 CA ASP E 311 1865 1907 1949 -16 6 2 C ATOM 2350 C ASP E 311 27.579 24.746 26.784 1.00 15.23 C ANISOU 2350 C ASP E 311 1897 1914 1974 -8 19 1 C ATOM 2351 O ASP E 311 28.005 23.620 26.520 1.00 15.70 O ANISOU 2351 O ASP E 311 1886 1972 2106 1 74 24 O ATOM 2352 CB ASP E 311 26.407 24.936 28.988 1.00 16.12 C ANISOU 2352 CB ASP E 311 2021 2067 2035 -37 18 -7 C ATOM 2353 CG ASP E 311 27.111 23.701 29.490 1.00 18.40 C ANISOU 2353 CG ASP E 311 2349 2296 2343 55 28 49 C ATOM 2354 OD1 ASP E 311 26.578 22.593 29.249 1.00 22.18 O ANISOU 2354 OD1 ASP E 311 2923 2617 2884 -51 32 -15 O ATOM 2355 OD2 ASP E 311 28.196 23.745 30.117 1.00 21.86 O ANISOU 2355 OD2 ASP E 311 2721 2848 2735 -6 -100 14 O ATOM 2356 N ILE E 312 28.207 25.861 26.439 1.00 15.08 N ANISOU 2356 N ILE E 312 1855 1909 1964 -21 10 -15 N ATOM 2357 CA ILE E 312 29.541 25.839 25.874 1.00 15.56 C ANISOU 2357 CA ILE E 312 1957 1961 1991 -4 9 -8 C ATOM 2358 C ILE E 312 30.386 26.764 26.733 1.00 15.55 C ANISOU 2358 C ILE E 312 1935 1972 2000 -11 1 -4 C ATOM 2359 O ILE E 312 30.214 27.980 26.684 1.00 15.32 O ANISOU 2359 O ILE E 312 1903 1947 1969 -38 18 -24 O ATOM 2360 CB ILE E 312 29.543 26.333 24.423 1.00 15.58 C ANISOU 2360 CB ILE E 312 1968 1965 1986 -11 16 -1 C ATOM 2361 CG1 ILE E 312 28.672 25.433 23.549 1.00 16.36 C ANISOU 2361 CG1 ILE E 312 2099 2072 2044 -4 -36 -5 C ATOM 2362 CG2 ILE E 312 30.974 26.378 23.897 1.00 16.24 C ANISOU 2362 CG2 ILE E 312 2035 2041 2095 -17 16 10 C ATOM 2363 CD1 ILE E 312 28.589 25.904 22.110 1.00 17.00 C ANISOU 2363 CD1 ILE E 312 2208 2154 2095 12 -10 3 C ATOM 2364 N ASP E 313 31.267 26.187 27.544 1.00 16.03 N ANISOU 2364 N ASP E 313 2036 2019 2036 -3 -1 0 N ATOM 2365 CA ASP E 313 32.178 26.967 28.370 1.00 16.33 C ANISOU 2365 CA ASP E 313 2065 2066 2072 0 16 -5 C ATOM 2366 C ASP E 313 31.435 27.893 29.340 1.00 16.05 C ANISOU 2366 C ASP E 313 2024 2025 2046 -10 20 0 C ATOM 2367 O ASP E 313 31.865 29.004 29.577 1.00 16.44 O ANISOU 2367 O ASP E 313 2123 2038 2083 9 51 -10 O ATOM 2368 CB ASP E 313 33.125 27.789 27.475 1.00 16.62 C ANISOU 2368 CB ASP E 313 2119 2083 2111 -25 9 9 C ATOM 2369 CG ASP E 313 33.866 26.929 26.443 1.00 18.06 C ANISOU 2369 CG ASP E 313 2287 2281 2294 13 29 -20 C ATOM 2370 OD1 ASP E 313 34.281 25.807 26.809 1.00 20.16 O ANISOU 2370 OD1 ASP E 313 2601 2411 2646 36 -13 47 O ATOM 2371 OD2 ASP E 313 34.101 27.296 25.257 1.00 18.63 O ANISOU 2371 OD2 ASP E 313 2403 2406 2270 18 -1 -50 O ATOM 2372 N GLY E 314 30.310 27.437 29.887 1.00 15.66 N ANISOU 2372 N GLY E 314 1983 1984 1980 25 32 0 N ATOM 2373 CA GLY E 314 29.548 28.245 30.826 1.00 14.94 C ANISOU 2373 CA GLY E 314 1896 1890 1889 16 9 9 C ATOM 2374 C GLY E 314 28.559 29.210 30.184 1.00 14.27 C ANISOU 2374 C GLY E 314 1841 1818 1763 26 37 2 C ATOM 2375 O GLY E 314 27.955 30.028 30.883 1.00 15.41 O ANISOU 2375 O GLY E 314 2002 1954 1897 96 84 2 O ATOM 2376 N VAL E 315 28.420 29.160 28.863 1.00 12.28 N ANISOU 2376 N VAL E 315 1515 1556 1594 -33 -27 -33 N ATOM 2377 CA VAL E 315 27.478 30.023 28.169 1.00 11.45 C ANISOU 2377 CA VAL E 315 1450 1445 1456 -34 23 -21 C ATOM 2378 C VAL E 315 26.367 29.121 27.659 1.00 10.52 C ANISOU 2378 C VAL E 315 1303 1343 1349 -28 44 -13 C ATOM 2379 O VAL E 315 26.615 28.198 26.896 1.00 10.10 O ANISOU 2379 O VAL E 315 1153 1365 1318 -44 132 11 O ATOM 2380 CB VAL E 315 28.113 30.749 26.973 1.00 11.31 C ANISOU 2380 CB VAL E 315 1437 1440 1421 -14 -2 -22 C ATOM 2381 CG1 VAL E 315 27.055 31.583 26.240 1.00 11.53 C ANISOU 2381 CG1 VAL E 315 1443 1420 1515 -23 31 0 C ATOM 2382 CG2 VAL E 315 29.276 31.616 27.409 1.00 11.73 C ANISOU 2382 CG2 VAL E 315 1455 1472 1527 -11 29 -4 C ATOM 2383 N PRO E 316 25.138 29.353 28.084 1.00 9.96 N ANISOU 2383 N PRO E 316 1264 1276 1242 1 13 -22 N ATOM 2384 CA PRO E 316 24.032 28.492 27.663 1.00 9.52 C ANISOU 2384 CA PRO E 316 1228 1191 1198 -2 25 -19 C ATOM 2385 C PRO E 316 23.485 28.805 26.282 1.00 9.47 C ANISOU 2385 C PRO E 316 1239 1166 1190 0 24 8 C ATOM 2386 O PRO E 316 23.413 29.960 25.883 1.00 10.27 O ANISOU 2386 O PRO E 316 1452 1204 1244 44 10 -21 O ATOM 2387 CB PRO E 316 22.982 28.771 28.724 1.00 9.85 C ANISOU 2387 CB PRO E 316 1247 1228 1265 -1 24 -9 C ATOM 2388 CG PRO E 316 23.180 30.239 28.976 1.00 10.18 C ANISOU 2388 CG PRO E 316 1295 1270 1300 0 34 -39 C ATOM 2389 CD PRO E 316 24.679 30.395 29.020 1.00 10.37 C ANISOU 2389 CD PRO E 316 1316 1243 1379 0 24 -17 C ATOM 2390 N HIS E 317 23.126 27.751 25.563 1.00 8.57 N ANISOU 2390 N HIS E 317 1034 1110 1111 14 -9 1 N ATOM 2391 CA HIS E 317 22.489 27.857 24.262 1.00 8.66 C ANISOU 2391 CA HIS E 317 1128 1081 1081 22 -2 6 C ATOM 2392 C HIS E 317 21.289 26.939 24.253 1.00 8.61 C ANISOU 2392 C HIS E 317 1072 1085 1111 34 1 7 C ATOM 2393 O HIS E 317 21.341 25.844 24.817 1.00 9.62 O ANISOU 2393 O HIS E 317 1126 1199 1330 18 -2 128 O ATOM 2394 CB HIS E 317 23.423 27.402 23.155 1.00 8.58 C ANISOU 2394 CB HIS E 317 1104 1112 1041 28 -43 -10 C ATOM 2395 CG HIS E 317 24.659 28.224 23.035 1.00 9.35 C ANISOU 2395 CG HIS E 317 1203 1186 1163 3 109 -26 C ATOM 2396 ND1 HIS E 317 24.780 29.242 22.122 1.00 11.26 N ANISOU 2396 ND1 HIS E 317 1479 1347 1451 37 117 42 N ATOM 2397 CD2 HIS E 317 25.821 28.195 23.727 1.00 10.54 C ANISOU 2397 CD2 HIS E 317 1337 1374 1291 48 58 35 C ATOM 2398 CE1 HIS E 317 25.976 29.796 22.241 1.00 10.99 C ANISOU 2398 CE1 HIS E 317 1434 1392 1349 0 -5 -14 C ATOM 2399 NE2 HIS E 317 26.626 29.184 23.215 1.00 11.70 N ANISOU 2399 NE2 HIS E 317 1580 1361 1501 37 42 9 N ATOM 2400 N LEU E 318 20.202 27.373 23.629 1.00 8.09 N ANISOU 2400 N LEU E 318 1104 1019 951 53 -18 -6 N ATOM 2401 CA LEU E 318 19.031 26.532 23.452 1.00 8.45 C ANISOU 2401 CA LEU E 318 1162 1042 1004 34 2 -46 C ATOM 2402 C LEU E 318 19.107 25.929 22.061 1.00 7.88 C ANISOU 2402 C LEU E 318 1078 977 938 15 -7 -21 C ATOM 2403 O LEU E 318 19.245 26.658 21.089 1.00 8.08 O ANISOU 2403 O LEU E 318 1200 956 913 121 32 -73 O ATOM 2404 CB LEU E 318 17.754 27.364 23.539 1.00 8.90 C ANISOU 2404 CB LEU E 318 1130 1026 1222 -6 -44 -22 C ATOM 2405 CG LEU E 318 16.970 27.480 24.845 1.00 12.99 C ANISOU 2405 CG LEU E 318 1783 1532 1619 112 37 -40 C ATOM 2406 CD1 LEU E 318 17.608 26.976 26.107 1.00 11.34 C ANISOU 2406 CD1 LEU E 318 1534 1341 1432 -52 -23 -170 C ATOM 2407 CD2 LEU E 318 16.317 28.829 24.929 1.00 11.47 C ANISOU 2407 CD2 LEU E 318 1649 1381 1326 -28 -23 -117 C ATOM 2408 N ILE E 319 19.054 24.610 21.977 1.00 7.09 N ANISOU 2408 N ILE E 319 1028 868 796 -40 -34 -50 N ATOM 2409 CA ILE E 319 19.126 23.948 20.674 1.00 7.61 C ANISOU 2409 CA ILE E 319 974 965 951 -21 28 -57 C ATOM 2410 C ILE E 319 17.934 23.024 20.492 1.00 7.73 C ANISOU 2410 C ILE E 319 1028 929 978 -32 37 -35 C ATOM 2411 O ILE E 319 17.371 22.531 21.460 1.00 8.46 O ANISOU 2411 O ILE E 319 1191 999 1024 30 93 -35 O ATOM 2412 CB ILE E 319 20.444 23.167 20.518 1.00 7.87 C ANISOU 2412 CB ILE E 319 1010 1008 969 -11 -22 -53 C ATOM 2413 CG1 ILE E 319 20.596 22.095 21.597 1.00 9.07 C ANISOU 2413 CG1 ILE E 319 1112 1066 1266 9 23 18 C ATOM 2414 CG2 ILE E 319 21.633 24.151 20.532 1.00 8.29 C ANISOU 2414 CG2 ILE E 319 1060 1000 1089 -6 -71 -74 C ATOM 2415 CD1 ILE E 319 21.746 21.106 21.279 1.00 11.13 C ANISOU 2415 CD1 ILE E 319 1372 1328 1528 83 14 -22 C ATOM 2416 N LEU E 320 17.556 22.811 19.243 1.00 7.89 N ANISOU 2416 N LEU E 320 974 1030 993 35 26 1 N ATOM 2417 CA LEU E 320 16.495 21.879 18.918 1.00 8.10 C ANISOU 2417 CA LEU E 320 1041 1026 1010 18 1 -66 C ATOM 2418 C LEU E 320 17.167 20.640 18.346 1.00 8.39 C ANISOU 2418 C LEU E 320 1065 1086 1036 25 17 -54 C ATOM 2419 O LEU E 320 18.012 20.753 17.433 1.00 8.45 O ANISOU 2419 O LEU E 320 1046 1021 1142 -16 40 -114 O ATOM 2420 CB LEU E 320 15.511 22.457 17.890 1.00 9.34 C ANISOU 2420 CB LEU E 320 1180 1242 1124 45 -15 -32 C ATOM 2421 CG LEU E 320 14.544 23.531 18.375 1.00 12.14 C ANISOU 2421 CG LEU E 320 1505 1560 1546 117 -13 -126 C ATOM 2422 CD1 LEU E 320 13.696 24.037 17.229 1.00 15.12 C ANISOU 2422 CD1 LEU E 320 1823 2035 1885 154 -61 53 C ATOM 2423 CD2 LEU E 320 13.629 22.967 19.411 1.00 13.84 C ANISOU 2423 CD2 LEU E 320 1788 1816 1653 61 -31 25 C ATOM 2424 N ILE E 321 16.779 19.497 18.902 1.00 8.30 N ANISOU 2424 N ILE E 321 1029 1062 1062 14 -2 -88 N ATOM 2425 CA ILE E 321 17.249 18.170 18.503 1.00 8.95 C ANISOU 2425 CA ILE E 321 1146 1101 1153 -23 10 -58 C ATOM 2426 C ILE E 321 16.062 17.392 17.975 1.00 8.29 C ANISOU 2426 C ILE E 321 1014 1063 1073 14 8 -79 C ATOM 2427 O ILE E 321 14.957 17.509 18.501 1.00 9.29 O ANISOU 2427 O ILE E 321 1074 1141 1315 -41 70 -135 O ATOM 2428 CB ILE E 321 17.807 17.444 19.733 1.00 10.50 C ANISOU 2428 CB ILE E 321 1291 1280 1418 23 -86 -52 C ATOM 2429 CG1 ILE E 321 18.960 18.275 20.317 1.00 11.77 C ANISOU 2429 CG1 ILE E 321 1423 1448 1598 -38 -100 -47 C ATOM 2430 CG2 ILE E 321 18.200 16.004 19.379 1.00 13.09 C ANISOU 2430 CG2 ILE E 321 1684 1544 1745 50 -29 -39 C ATOM 2431 CD1 ILE E 321 20.174 18.280 19.466 1.00 13.78 C ANISOU 2431 CD1 ILE E 321 1792 1705 1738 20 57 15 C ATOM 2432 N ALA E 322 16.264 16.579 16.945 1.00 7.03 N ANISOU 2432 N ALA E 322 894 877 900 -3 -30 -40 N ATOM 2433 CA ALA E 322 15.145 15.781 16.434 1.00 7.02 C ANISOU 2433 CA ALA E 322 841 895 931 -4 -9 19 C ATOM 2434 C ALA E 322 14.736 14.719 17.457 1.00 7.26 C ANISOU 2434 C ALA E 322 894 955 906 17 -8 20 C ATOM 2435 O ALA E 322 15.574 13.945 17.909 1.00 7.32 O ANISOU 2435 O ALA E 322 863 968 948 108 128 74 O ATOM 2436 CB ALA E 322 15.497 15.139 15.099 1.00 6.88 C ANISOU 2436 CB ALA E 322 879 755 977 0 -21 -23 C ATOM 2437 N SER E 323 13.440 14.659 17.785 1.00 7.86 N ANISOU 2437 N SER E 323 957 1024 1002 50 7 16 N ATOM 2438 CA SER E 323 12.927 13.696 18.758 1.00 8.66 C ANISOU 2438 CA SER E 323 1085 1126 1077 -3 19 4 C ATOM 2439 C SER E 323 12.539 12.355 18.129 1.00 8.41 C ANISOU 2439 C SER E 323 1081 1059 1055 11 20 46 C ATOM 2440 O SER E 323 12.265 11.365 18.817 1.00 9.56 O ANISOU 2440 O SER E 323 1194 1236 1202 -23 60 92 O ATOM 2441 CB SER E 323 11.746 14.314 19.517 1.00 9.57 C ANISOU 2441 CB SER E 323 1212 1218 1203 27 74 -20 C ATOM 2442 OG SER E 323 10.625 14.484 18.666 1.00 12.03 O ANISOU 2442 OG SER E 323 1451 1675 1443 111 88 -33 O ATOM 2443 N ARG E 324 12.526 12.338 16.805 1.00 8.06 N ANISOU 2443 N ARG E 324 1118 993 949 -3 52 3 N ATOM 2444 CA ARG E 324 12.249 11.151 16.012 1.00 8.03 C ANISOU 2444 CA ARG E 324 1039 1012 997 -43 23 16 C ATOM 2445 C ARG E 324 12.782 11.440 14.626 1.00 7.86 C ANISOU 2445 C ARG E 324 1014 1006 965 -31 33 0 C ATOM 2446 O ARG E 324 13.179 12.564 14.351 1.00 7.80 O ANISOU 2446 O ARG E 324 1019 1087 856 -71 55 38 O ATOM 2447 CB ARG E 324 10.750 10.911 15.887 1.00 8.39 C ANISOU 2447 CB ARG E 324 1066 1078 1042 -22 26 9 C ATOM 2448 CG ARG E 324 10.004 12.058 15.172 1.00 10.07 C ANISOU 2448 CG ARG E 324 1299 1287 1241 44 -42 51 C ATOM 2449 CD ARG E 324 8.497 11.853 15.202 1.00 13.25 C ANISOU 2449 CD ARG E 324 1562 1743 1727 27 55 78 C ATOM 2450 NE ARG E 324 7.598 12.812 14.561 1.00 13.82 N ANISOU 2450 NE ARG E 324 1662 1827 1762 7 39 155 N ATOM 2451 CZ ARG E 324 7.591 13.202 13.296 1.00 13.38 C ANISOU 2451 CZ ARG E 324 1700 1703 1682 40 -56 -49 C ATOM 2452 NH1 ARG E 324 8.517 12.829 12.420 1.00 14.21 N ANISOU 2452 NH1 ARG E 324 1798 1878 1723 63 58 29 N ATOM 2453 NH2 ARG E 324 6.650 14.052 12.927 1.00 13.42 N ANISOU 2453 NH2 ARG E 324 1497 1789 1811 12 -105 -22 N ATOM 2454 N ASP E 325 12.782 10.440 13.752 1.00 7.85 N ANISOU 2454 N ASP E 325 979 1032 968 -35 28 18 N ATOM 2455 CA ASP E 325 13.173 10.675 12.363 1.00 8.48 C ANISOU 2455 CA ASP E 325 1076 1123 1021 -1 -5 16 C ATOM 2456 C ASP E 325 12.164 11.672 11.775 1.00 8.55 C ANISOU 2456 C ASP E 325 1067 1152 1029 -15 -10 18 C ATOM 2457 O ASP E 325 10.954 11.555 12.007 1.00 9.64 O ANISOU 2457 O ASP E 325 1179 1376 1106 48 117 90 O ATOM 2458 CB ASP E 325 13.190 9.374 11.568 1.00 8.82 C ANISOU 2458 CB ASP E 325 1115 1127 1108 29 6 21 C ATOM 2459 CG ASP E 325 14.325 8.430 11.964 1.00 11.01 C ANISOU 2459 CG ASP E 325 1345 1389 1449 13 -35 69 C ATOM 2460 OD1 ASP E 325 15.207 8.787 12.785 1.00 12.34 O ANISOU 2460 OD1 ASP E 325 1587 1603 1496 24 -38 -6 O ATOM 2461 OD2 ASP E 325 14.405 7.289 11.450 1.00 13.78 O ANISOU 2461 OD2 ASP E 325 1828 1617 1789 83 27 -91 O ATOM 2462 N ILE E 326 12.664 12.659 11.037 1.00 7.88 N ANISOU 2462 N ILE E 326 1007 1047 939 25 21 20 N ATOM 2463 CA ILE E 326 11.828 13.684 10.424 1.00 7.81 C ANISOU 2463 CA ILE E 326 1012 1052 902 10 -6 34 C ATOM 2464 C ILE E 326 11.932 13.551 8.919 1.00 7.68 C ANISOU 2464 C ILE E 326 959 1041 916 -12 -16 52 C ATOM 2465 O ILE E 326 13.006 13.553 8.379 1.00 8.40 O ANISOU 2465 O ILE E 326 1082 1209 898 68 3 113 O ATOM 2466 CB ILE E 326 12.312 15.070 10.838 1.00 8.51 C ANISOU 2466 CB ILE E 326 1109 1078 1045 54 9 51 C ATOM 2467 CG1 ILE E 326 12.219 15.239 12.355 1.00 9.33 C ANISOU 2467 CG1 ILE E 326 1191 1195 1159 37 12 31 C ATOM 2468 CG2 ILE E 326 11.500 16.144 10.131 1.00 8.89 C ANISOU 2468 CG2 ILE E 326 1128 1108 1141 46 -27 45 C ATOM 2469 CD1 ILE E 326 12.830 16.496 12.872 1.00 10.29 C ANISOU 2469 CD1 ILE E 326 1433 1276 1200 114 -56 -42 C ATOM 2470 N ALA E 327 10.802 13.430 8.250 1.00 7.41 N ANISOU 2470 N ALA E 327 901 1028 883 -5 10 84 N ATOM 2471 CA ALA E 327 10.811 13.247 6.821 1.00 7.42 C ANISOU 2471 CA ALA E 327 947 965 908 1 -18 23 C ATOM 2472 C ALA E 327 11.044 14.552 6.076 1.00 6.92 C ANISOU 2472 C ALA E 327 906 877 843 -20 -12 -10 C ATOM 2473 O ALA E 327 10.609 15.614 6.508 1.00 6.89 O ANISOU 2473 O ALA E 327 811 944 860 4 43 -6 O ATOM 2474 CB ALA E 327 9.498 12.671 6.388 1.00 7.62 C ANISOU 2474 CB ALA E 327 937 1034 923 -10 -18 33 C ATOM 2475 N ALA E 328 11.694 14.457 4.923 1.00 7.16 N ANISOU 2475 N ALA E 328 881 917 921 39 14 17 N ATOM 2476 CA ALA E 328 11.797 15.602 4.044 1.00 7.09 C ANISOU 2476 CA ALA E 328 890 913 889 -11 -2 19 C ATOM 2477 C ALA E 328 10.377 16.096 3.766 1.00 7.37 C ANISOU 2477 C ALA E 328 940 953 907 -17 -22 15 C ATOM 2478 O ALA E 328 9.445 15.292 3.546 1.00 8.33 O ANISOU 2478 O ALA E 328 970 1111 1081 -63 -25 47 O ATOM 2479 CB ALA E 328 12.488 15.223 2.755 1.00 7.33 C ANISOU 2479 CB ALA E 328 902 942 941 32 -41 64 C ATOM 2480 N GLY E 329 10.198 17.409 3.786 1.00 7.31 N ANISOU 2480 N GLY E 329 967 947 863 -2 -24 -16 N ATOM 2481 CA GLY E 329 8.907 18.005 3.481 1.00 7.48 C ANISOU 2481 CA GLY E 329 931 1010 900 8 7 27 C ATOM 2482 C GLY E 329 8.000 18.247 4.662 1.00 8.09 C ANISOU 2482 C GLY E 329 974 1058 1038 41 21 33 C ATOM 2483 O GLY E 329 6.950 18.892 4.523 1.00 9.60 O ANISOU 2483 O GLY E 329 1157 1269 1220 98 73 103 O ATOM 2484 N GLU E 330 8.377 17.691 5.806 1.00 7.82 N ANISOU 2484 N GLU E 330 947 1016 1008 17 1 -53 N ATOM 2485 CA GLU E 330 7.613 17.826 7.020 1.00 8.25 C ANISOU 2485 CA GLU E 330 1060 1091 984 26 -18 -23 C ATOM 2486 C GLU E 330 7.946 19.142 7.723 1.00 7.11 C ANISOU 2486 C GLU E 330 836 913 953 -44 8 -3 C ATOM 2487 O GLU E 330 9.116 19.563 7.737 1.00 8.24 O ANISOU 2487 O GLU E 330 925 1059 1147 25 19 -67 O ATOM 2488 CB GLU E 330 7.981 16.676 7.955 1.00 10.50 C ANISOU 2488 CB GLU E 330 1352 1218 1419 55 49 17 C ATOM 2489 CG GLU E 330 7.091 16.551 9.127 1.00 12.68 C ANISOU 2489 CG GLU E 330 1672 1542 1604 -1 -6 22 C ATOM 2490 CD GLU E 330 7.424 15.375 10.030 1.00 10.52 C ANISOU 2490 CD GLU E 330 1291 1314 1389 -127 -205 3 C ATOM 2491 OE1 GLU E 330 8.201 14.415 9.679 1.00 12.19 O ANISOU 2491 OE1 GLU E 330 1426 1727 1476 -79 -127 -60 O ATOM 2492 OE2 GLU E 330 6.870 15.412 11.100 1.00 14.23 O ANISOU 2492 OE2 GLU E 330 1767 1725 1912 -88 -10 -179 O ATOM 2493 N GLU E 331 6.935 19.781 8.316 1.00 6.95 N ANISOU 2493 N GLU E 331 955 876 808 -13 -46 -62 N ATOM 2494 CA GLU E 331 7.150 20.966 9.147 1.00 6.90 C ANISOU 2494 CA GLU E 331 904 855 862 -40 -7 2 C ATOM 2495 C GLU E 331 7.847 20.595 10.451 1.00 6.40 C ANISOU 2495 C GLU E 331 805 808 819 7 21 -35 C ATOM 2496 O GLU E 331 7.483 19.607 11.087 1.00 6.36 O ANISOU 2496 O GLU E 331 794 792 830 -41 -52 27 O ATOM 2497 CB GLU E 331 5.836 21.655 9.490 1.00 7.28 C ANISOU 2497 CB GLU E 331 963 934 868 -14 -52 -21 C ATOM 2498 CG GLU E 331 6.040 23.027 10.102 1.00 9.31 C ANISOU 2498 CG GLU E 331 1379 1110 1047 73 82 4 C ATOM 2499 CD GLU E 331 4.770 23.727 10.564 1.00 9.42 C ANISOU 2499 CD GLU E 331 1131 1225 1224 40 -70 3 C ATOM 2500 OE1 GLU E 331 3.637 23.163 10.519 1.00 11.58 O ANISOU 2500 OE1 GLU E 331 1383 1533 1482 59 -121 67 O ATOM 2501 OE2 GLU E 331 4.946 24.888 10.982 1.00 10.13 O ANISOU 2501 OE2 GLU E 331 1333 1232 1283 155 -68 23 O ATOM 2502 N LEU E 332 8.852 21.383 10.843 1.00 6.35 N ANISOU 2502 N LEU E 332 819 803 788 -29 0 -5 N ATOM 2503 CA LEU E 332 9.498 21.208 12.133 1.00 6.39 C ANISOU 2503 CA LEU E 332 811 767 849 13 -5 10 C ATOM 2504 C LEU E 332 8.591 21.820 13.193 1.00 5.77 C ANISOU 2504 C LEU E 332 839 733 619 20 -54 20 C ATOM 2505 O LEU E 332 8.050 22.922 12.995 1.00 6.38 O ANISOU 2505 O LEU E 332 895 735 791 4 -40 7 O ATOM 2506 CB LEU E 332 10.843 21.928 12.140 1.00 6.63 C ANISOU 2506 CB LEU E 332 847 824 845 -4 -52 6 C ATOM 2507 CG LEU E 332 11.900 21.403 11.182 1.00 8.25 C ANISOU 2507 CG LEU E 332 983 1102 1047 50 -33 -23 C ATOM 2508 CD1 LEU E 332 13.181 22.211 11.358 1.00 11.27 C ANISOU 2508 CD1 LEU E 332 1250 1412 1616 16 -20 -9 C ATOM 2509 CD2 LEU E 332 12.166 19.929 11.414 1.00 10.60 C ANISOU 2509 CD2 LEU E 332 1310 1259 1458 -11 51 37 C ATOM 2510 N LEU E 333 8.446 21.137 14.329 1.00 6.01 N ANISOU 2510 N LEU E 333 886 712 684 24 30 20 N ATOM 2511 CA LEU E 333 7.565 21.586 15.411 1.00 5.44 C ANISOU 2511 CA LEU E 333 681 718 664 38 -10 23 C ATOM 2512 C LEU E 333 8.080 21.147 16.750 1.00 5.33 C ANISOU 2512 C LEU E 333 729 666 627 24 -18 -33 C ATOM 2513 O LEU E 333 8.593 20.043 16.879 1.00 6.36 O ANISOU 2513 O LEU E 333 895 744 776 30 -102 -40 O ATOM 2514 CB LEU E 333 6.178 20.958 15.249 1.00 5.87 C ANISOU 2514 CB LEU E 333 734 759 737 50 -67 -41 C ATOM 2515 CG LEU E 333 5.426 21.355 13.982 1.00 6.65 C ANISOU 2515 CG LEU E 333 866 821 838 64 -81 21 C ATOM 2516 CD1 LEU E 333 4.229 20.442 13.745 1.00 6.04 C ANISOU 2516 CD1 LEU E 333 813 784 695 51 12 9 C ATOM 2517 CD2 LEU E 333 5.000 22.802 14.037 1.00 6.41 C ANISOU 2517 CD2 LEU E 333 926 753 756 32 -144 12 C ATOM 2518 N TYR E 334 7.914 21.991 17.763 1.00 5.67 N ANISOU 2518 N TYR E 334 798 686 670 51 12 -35 N ATOM 2519 CA TYR E 334 8.297 21.630 19.135 1.00 5.35 C ANISOU 2519 CA TYR E 334 764 636 630 23 -31 -56 C ATOM 2520 C TYR E 334 7.329 22.275 20.109 1.00 5.56 C ANISOU 2520 C TYR E 334 680 724 705 17 -24 18 C ATOM 2521 O TYR E 334 6.547 23.155 19.757 1.00 6.18 O ANISOU 2521 O TYR E 334 866 675 806 39 -97 46 O ATOM 2522 CB TYR E 334 9.726 22.031 19.472 1.00 5.69 C ANISOU 2522 CB TYR E 334 791 721 648 14 -6 34 C ATOM 2523 CG TYR E 334 9.973 23.523 19.536 1.00 5.59 C ANISOU 2523 CG TYR E 334 813 655 656 -2 -77 -7 C ATOM 2524 CD1 TYR E 334 9.988 24.195 20.743 1.00 6.63 C ANISOU 2524 CD1 TYR E 334 1054 802 662 37 -91 -55 C ATOM 2525 CD2 TYR E 334 10.236 24.263 18.398 1.00 7.14 C ANISOU 2525 CD2 TYR E 334 1033 922 758 -10 -12 0 C ATOM 2526 CE1 TYR E 334 10.229 25.545 20.811 1.00 7.40 C ANISOU 2526 CE1 TYR E 334 977 901 930 -54 21 9 C ATOM 2527 CE2 TYR E 334 10.451 25.596 18.458 1.00 6.63 C ANISOU 2527 CE2 TYR E 334 950 920 646 -65 -47 79 C ATOM 2528 CZ TYR E 334 10.458 26.254 19.659 1.00 6.80 C ANISOU 2528 CZ TYR E 334 879 862 843 -21 -109 -10 C ATOM 2529 OH TYR E 334 10.687 27.606 19.668 1.00 7.66 O ANISOU 2529 OH TYR E 334 1129 925 856 -18 -101 38 O ATOM 2530 N ASP E 335 7.394 21.835 21.348 1.00 6.10 N ANISOU 2530 N ASP E 335 818 748 751 17 0 24 N ATOM 2531 CA ASP E 335 6.525 22.340 22.376 1.00 6.59 C ANISOU 2531 CA ASP E 335 881 836 786 8 -6 -26 C ATOM 2532 C ASP E 335 7.090 23.651 22.935 1.00 6.27 C ANISOU 2532 C ASP E 335 790 773 816 13 -54 -9 C ATOM 2533 O ASP E 335 8.145 23.667 23.585 1.00 5.63 O ANISOU 2533 O ASP E 335 697 796 644 -12 -29 -81 O ATOM 2534 CB ASP E 335 6.394 21.262 23.462 1.00 7.37 C ANISOU 2534 CB ASP E 335 997 856 945 -2 15 46 C ATOM 2535 CG ASP E 335 5.553 21.680 24.636 1.00 9.94 C ANISOU 2535 CG ASP E 335 1358 1182 1236 107 75 25 C ATOM 2536 OD1 ASP E 335 4.841 22.711 24.572 1.00 8.06 O ANISOU 2536 OD1 ASP E 335 1209 839 1014 -82 -58 -3 O ATOM 2537 OD2 ASP E 335 5.515 20.973 25.688 1.00 14.93 O ANISOU 2537 OD2 ASP E 335 2321 1721 1631 208 187 250 O ATOM 2538 N TYR E 336 6.379 24.748 22.672 1.00 5.65 N ANISOU 2538 N TYR E 336 756 693 695 6 -31 -21 N ATOM 2539 CA TYR E 336 6.767 26.068 23.181 1.00 5.04 C ANISOU 2539 CA TYR E 336 650 666 598 -32 -13 -13 C ATOM 2540 C TYR E 336 6.821 26.096 24.713 1.00 5.44 C ANISOU 2540 C TYR E 336 744 678 643 -15 -1 -40 C ATOM 2541 O TYR E 336 7.582 26.872 25.287 1.00 6.59 O ANISOU 2541 O TYR E 336 912 899 690 -76 -96 -65 O ATOM 2542 CB TYR E 336 5.801 27.138 22.712 1.00 4.54 C ANISOU 2542 CB TYR E 336 583 585 556 0 41 -36 C ATOM 2543 CG TYR E 336 5.999 27.616 21.282 1.00 3.61 C ANISOU 2543 CG TYR E 336 538 410 424 -16 -26 -21 C ATOM 2544 CD1 TYR E 336 6.882 26.987 20.386 1.00 4.84 C ANISOU 2544 CD1 TYR E 336 559 756 524 97 -87 10 C ATOM 2545 CD2 TYR E 336 5.287 28.710 20.803 1.00 4.76 C ANISOU 2545 CD2 TYR E 336 598 602 608 145 5 -49 C ATOM 2546 CE1 TYR E 336 7.022 27.431 19.081 1.00 3.77 C ANISOU 2546 CE1 TYR E 336 468 418 545 9 40 7 C ATOM 2547 CE2 TYR E 336 5.424 29.149 19.524 1.00 5.08 C ANISOU 2547 CE2 TYR E 336 688 646 594 78 23 -28 C ATOM 2548 CZ TYR E 336 6.312 28.531 18.649 1.00 4.21 C ANISOU 2548 CZ TYR E 336 542 535 522 42 -33 -33 C ATOM 2549 OH TYR E 336 6.428 29.033 17.370 1.00 4.91 O ANISOU 2549 OH TYR E 336 637 712 516 0 -14 -96 O ATOM 2550 N GLY E 337 6.022 25.268 25.364 1.00 5.46 N ANISOU 2550 N GLY E 337 741 710 622 -6 0 -79 N ATOM 2551 CA GLY E 337 6.102 25.166 26.816 1.00 6.06 C ANISOU 2551 CA GLY E 337 834 771 696 -16 41 -21 C ATOM 2552 C GLY E 337 5.353 26.199 27.627 1.00 6.96 C ANISOU 2552 C GLY E 337 927 858 857 40 10 -24 C ATOM 2553 O GLY E 337 5.381 26.151 28.870 1.00 7.34 O ANISOU 2553 O GLY E 337 1033 901 853 45 -49 -4 O ATOM 2554 N ASP E 338 4.688 27.132 26.958 1.00 7.34 N ANISOU 2554 N ASP E 338 1033 903 852 33 -46 24 N ATOM 2555 CA ASP E 338 3.866 28.126 27.647 1.00 7.22 C ANISOU 2555 CA ASP E 338 914 963 863 13 17 12 C ATOM 2556 C ASP E 338 2.545 27.458 27.992 1.00 7.98 C ANISOU 2556 C ASP E 338 1003 999 1029 30 -49 -13 C ATOM 2557 O ASP E 338 1.777 27.103 27.109 1.00 8.17 O ANISOU 2557 O ASP E 338 1058 1102 944 68 -56 34 O ATOM 2558 CB ASP E 338 3.663 29.380 26.790 1.00 7.73 C ANISOU 2558 CB ASP E 338 973 988 977 26 -3 -10 C ATOM 2559 CG ASP E 338 2.980 30.508 27.540 1.00 8.53 C ANISOU 2559 CG ASP E 338 1048 1045 1145 36 0 34 C ATOM 2560 OD1 ASP E 338 2.353 30.247 28.587 1.00 7.98 O ANISOU 2560 OD1 ASP E 338 1187 991 853 155 -87 59 O ATOM 2561 OD2 ASP E 338 3.007 31.693 27.120 1.00 8.69 O ANISOU 2561 OD2 ASP E 338 1201 971 1128 -81 -79 45 O ATOM 2562 N ARG E 339 2.326 27.265 29.291 1.00 8.20 N ANISOU 2562 N ARG E 339 990 1080 1045 18 11 47 N ATOM 2563 CA ARG E 339 1.149 26.567 29.784 1.00 9.45 C ANISOU 2563 CA ARG E 339 1183 1214 1193 -5 -4 61 C ATOM 2564 C ARG E 339 0.248 27.507 30.579 1.00 9.62 C ANISOU 2564 C ARG E 339 1201 1265 1189 17 -4 49 C ATOM 2565 O ARG E 339 -0.769 27.088 31.137 1.00 10.65 O ANISOU 2565 O ARG E 339 1266 1386 1395 26 -27 128 O ATOM 2566 CB ARG E 339 1.602 25.346 30.594 1.00 9.77 C ANISOU 2566 CB ARG E 339 1250 1240 1218 -5 0 76 C ATOM 2567 CG ARG E 339 2.254 24.328 29.675 1.00 11.37 C ANISOU 2567 CG ARG E 339 1362 1426 1532 11 24 31 C ATOM 2568 CD ARG E 339 2.748 23.059 30.316 1.00 12.72 C ANISOU 2568 CD ARG E 339 1585 1551 1694 -20 9 111 C ATOM 2569 NE ARG E 339 3.544 22.317 29.345 1.00 14.96 N ANISOU 2569 NE ARG E 339 1949 1838 1895 17 56 12 N ATOM 2570 CZ ARG E 339 4.273 21.240 29.614 1.00 16.21 C ANISOU 2570 CZ ARG E 339 2041 2001 2117 33 17 -10 C ATOM 2571 NH1 ARG E 339 4.290 20.716 30.834 1.00 17.73 N ANISOU 2571 NH1 ARG E 339 2273 2214 2247 61 -16 56 N ATOM 2572 NH2 ARG E 339 4.979 20.671 28.644 1.00 17.02 N ANISOU 2572 NH2 ARG E 339 2192 2192 2080 26 66 -27 N ATOM 2573 N SER E 340 0.599 28.793 30.587 1.00 9.89 N ANISOU 2573 N SER E 340 1237 1321 1199 10 0 26 N ATOM 2574 CA SER E 340 -0.163 29.792 31.329 1.00 10.93 C ANISOU 2574 CA SER E 340 1408 1411 1331 24 11 1 C ATOM 2575 C SER E 340 -1.582 29.923 30.798 1.00 11.26 C ANISOU 2575 C SER E 340 1449 1461 1367 35 19 -1 C ATOM 2576 O SER E 340 -1.831 29.887 29.589 1.00 11.14 O ANISOU 2576 O SER E 340 1461 1484 1286 33 27 17 O ATOM 2577 CB SER E 340 0.572 31.144 31.355 1.00 11.11 C ANISOU 2577 CB SER E 340 1411 1410 1396 32 30 -10 C ATOM 2578 OG SER E 340 0.592 31.802 30.105 1.00 12.18 O ANISOU 2578 OG SER E 340 1688 1486 1453 89 22 -5 O ATOM 2579 N LYS E 341 -2.537 30.033 31.709 1.00 12.15 N ANISOU 2579 N LYS E 341 1535 1578 1501 9 51 58 N ATOM 2580 CA LYS E 341 -3.921 30.148 31.285 1.00 12.85 C ANISOU 2580 CA LYS E 341 1613 1634 1632 6 -6 37 C ATOM 2581 C LYS E 341 -4.148 31.420 30.448 1.00 12.03 C ANISOU 2581 C LYS E 341 1482 1563 1526 1 30 7 C ATOM 2582 O LYS E 341 -4.954 31.415 29.521 1.00 12.26 O ANISOU 2582 O LYS E 341 1565 1633 1461 38 45 69 O ATOM 2583 CB LYS E 341 -4.846 30.066 32.490 1.00 14.00 C ANISOU 2583 CB LYS E 341 1766 1790 1762 2 0 30 C ATOM 2584 CG LYS E 341 -4.860 28.659 33.125 1.00 16.18 C ANISOU 2584 CG LYS E 341 2094 1969 2084 15 -5 80 C ATOM 2585 CD LYS E 341 -5.382 27.588 32.153 1.00 19.03 C ANISOU 2585 CD LYS E 341 2463 2337 2431 -32 -88 -34 C ATOM 2586 CE LYS E 341 -5.090 26.172 32.642 1.00 20.15 C ANISOU 2586 CE LYS E 341 2631 2458 2564 -1 -37 36 C ATOM 2587 NZ LYS E 341 -3.643 25.856 32.490 1.00 22.08 N ANISOU 2587 NZ LYS E 341 2775 2739 2876 39 -26 -15 N ATOM 2588 N ALA E 342 -3.419 32.488 30.754 1.00 11.42 N ANISOU 2588 N ALA E 342 1474 1451 1412 32 53 -8 N ATOM 2589 CA ALA E 342 -3.526 33.732 29.987 1.00 10.95 C ANISOU 2589 CA ALA E 342 1417 1387 1354 22 19 -13 C ATOM 2590 C ALA E 342 -3.063 33.551 28.537 1.00 10.34 C ANISOU 2590 C ALA E 342 1317 1304 1307 15 -4 -16 C ATOM 2591 O ALA E 342 -3.671 34.078 27.601 1.00 10.53 O ANISOU 2591 O ALA E 342 1470 1232 1297 47 18 0 O ATOM 2592 CB ALA E 342 -2.720 34.805 30.637 1.00 11.29 C ANISOU 2592 CB ALA E 342 1437 1427 1423 -10 5 19 C ATOM 2593 N SER E 343 -1.973 32.820 28.353 1.00 9.60 N ANISOU 2593 N SER E 343 1262 1182 1202 12 -4 -52 N ATOM 2594 CA SER E 343 -1.466 32.583 27.006 1.00 9.11 C ANISOU 2594 CA SER E 343 1167 1138 1155 19 -17 -18 C ATOM 2595 C SER E 343 -2.394 31.671 26.228 1.00 9.38 C ANISOU 2595 C SER E 343 1168 1185 1210 4 -11 -23 C ATOM 2596 O SER E 343 -2.679 31.914 25.042 1.00 8.88 O ANISOU 2596 O SER E 343 1122 1155 1097 53 -22 -21 O ATOM 2597 CB SER E 343 -0.061 31.990 27.046 1.00 8.52 C ANISOU 2597 CB SER E 343 1065 1073 1097 -17 7 -32 C ATOM 2598 OG SER E 343 0.853 32.939 27.548 1.00 8.33 O ANISOU 2598 OG SER E 343 1081 1045 1038 26 -60 -24 O ATOM 2599 N ILE E 344 -2.853 30.607 26.874 1.00 10.07 N ANISOU 2599 N ILE E 344 1308 1272 1246 30 16 -2 N ATOM 2600 CA ILE E 344 -3.726 29.648 26.187 1.00 10.69 C ANISOU 2600 CA ILE E 344 1335 1354 1372 -21 -37 -5 C ATOM 2601 C ILE E 344 -5.075 30.257 25.786 1.00 10.88 C ANISOU 2601 C ILE E 344 1390 1382 1360 13 -7 6 C ATOM 2602 O ILE E 344 -5.654 29.899 24.749 1.00 10.28 O ANISOU 2602 O ILE E 344 1309 1332 1263 -13 0 -55 O ATOM 2603 CB ILE E 344 -3.907 28.395 27.044 1.00 10.99 C ANISOU 2603 CB ILE E 344 1392 1385 1399 0 -28 1 C ATOM 2604 CG1 ILE E 344 -2.622 27.566 26.995 1.00 11.90 C ANISOU 2604 CG1 ILE E 344 1453 1554 1511 15 52 1 C ATOM 2605 CG2 ILE E 344 -5.059 27.537 26.530 1.00 11.88 C ANISOU 2605 CG2 ILE E 344 1464 1456 1593 -45 -40 28 C ATOM 2606 CD1 ILE E 344 -2.544 26.534 28.078 1.00 14.12 C ANISOU 2606 CD1 ILE E 344 1771 1710 1884 13 -7 98 C ATOM 2607 N GLU E 345 -5.567 31.163 26.621 1.00 11.48 N ANISOU 2607 N GLU E 345 1489 1434 1439 4 -13 14 N ATOM 2608 CA GLU E 345 -6.802 31.888 26.373 1.00 11.91 C ANISOU 2608 CA GLU E 345 1490 1517 1515 -1 1 31 C ATOM 2609 C GLU E 345 -6.709 32.647 25.053 1.00 11.31 C ANISOU 2609 C GLU E 345 1410 1436 1449 -17 -14 13 C ATOM 2610 O GLU E 345 -7.627 32.611 24.231 1.00 11.59 O ANISOU 2610 O GLU E 345 1427 1470 1505 9 -44 65 O ATOM 2611 CB GLU E 345 -7.028 32.871 27.528 1.00 12.55 C ANISOU 2611 CB GLU E 345 1617 1558 1590 -11 -2 14 C ATOM 2612 CG GLU E 345 -8.416 33.483 27.640 1.00 15.12 C ANISOU 2612 CG GLU E 345 1829 1913 2001 20 0 65 C ATOM 2613 CD GLU E 345 -8.653 34.114 29.013 1.00 17.89 C ANISOU 2613 CD GLU E 345 2349 2252 2196 6 15 -38 C ATOM 2614 OE1 GLU E 345 -8.217 33.524 30.032 1.00 19.73 O ANISOU 2614 OE1 GLU E 345 2662 2411 2423 40 -71 48 O ATOM 2615 OE2 GLU E 345 -9.260 35.211 29.088 1.00 19.63 O ANISOU 2615 OE2 GLU E 345 2562 2387 2508 81 -18 38 O ATOM 2616 N ALA E 346 -5.574 33.304 24.846 1.00 10.58 N ANISOU 2616 N ALA E 346 1330 1333 1357 0 9 15 N ATOM 2617 CA ALA E 346 -5.348 34.110 23.655 1.00 10.01 C ANISOU 2617 CA ALA E 346 1269 1256 1278 19 -13 -6 C ATOM 2618 C ALA E 346 -4.843 33.301 22.464 1.00 9.71 C ANISOU 2618 C ALA E 346 1210 1247 1230 -1 1 10 C ATOM 2619 O ALA E 346 -5.017 33.721 21.316 1.00 9.58 O ANISOU 2619 O ALA E 346 1188 1219 1231 35 -18 16 O ATOM 2620 CB ALA E 346 -4.359 35.212 23.974 1.00 10.14 C ANISOU 2620 CB ALA E 346 1237 1252 1361 9 3 34 C ATOM 2621 N HIS E 347 -4.217 32.156 22.741 1.00 9.29 N ANISOU 2621 N HIS E 347 1183 1179 1165 7 10 7 N ATOM 2622 CA HIS E 347 -3.617 31.317 21.701 1.00 9.61 C ANISOU 2622 CA HIS E 347 1242 1221 1189 6 9 0 C ATOM 2623 C HIS E 347 -3.972 29.873 21.944 1.00 9.42 C ANISOU 2623 C HIS E 347 1197 1195 1185 -8 12 -4 C ATOM 2624 O HIS E 347 -3.171 29.113 22.486 1.00 8.97 O ANISOU 2624 O HIS E 347 1114 1117 1177 -92 27 -35 O ATOM 2625 CB HIS E 347 -2.099 31.480 21.678 1.00 9.92 C ANISOU 2625 CB HIS E 347 1302 1269 1196 -6 -9 2 C ATOM 2626 CG HIS E 347 -1.667 32.904 21.619 1.00 11.39 C ANISOU 2626 CG HIS E 347 1451 1409 1464 -3 16 30 C ATOM 2627 ND1 HIS E 347 -1.658 33.627 20.445 1.00 12.69 N ANISOU 2627 ND1 HIS E 347 1685 1593 1544 -16 26 86 N ATOM 2628 CD2 HIS E 347 -1.293 33.759 22.597 1.00 11.56 C ANISOU 2628 CD2 HIS E 347 1435 1490 1467 30 -4 24 C ATOM 2629 CE1 HIS E 347 -1.270 34.864 20.704 1.00 12.94 C ANISOU 2629 CE1 HIS E 347 1635 1637 1643 -3 -6 2 C ATOM 2630 NE2 HIS E 347 -1.045 34.969 22.001 1.00 13.26 N ANISOU 2630 NE2 HIS E 347 1696 1625 1715 -7 33 62 N ATOM 2631 N PRO E 348 -5.177 29.489 21.542 1.00 10.41 N ANISOU 2631 N PRO E 348 1290 1297 1367 0 -3 6 N ATOM 2632 CA PRO E 348 -5.663 28.139 21.819 1.00 10.87 C ANISOU 2632 CA PRO E 348 1380 1340 1409 -1 5 15 C ATOM 2633 C PRO E 348 -4.791 27.044 21.211 1.00 10.90 C ANISOU 2633 C PRO E 348 1362 1352 1426 8 46 10 C ATOM 2634 O PRO E 348 -4.797 25.936 21.774 1.00 11.08 O ANISOU 2634 O PRO E 348 1385 1366 1459 18 82 40 O ATOM 2635 CB PRO E 348 -7.062 28.140 21.201 1.00 10.84 C ANISOU 2635 CB PRO E 348 1344 1376 1397 -15 35 6 C ATOM 2636 CG PRO E 348 -7.013 29.204 20.181 1.00 11.31 C ANISOU 2636 CG PRO E 348 1431 1380 1487 -16 -31 30 C ATOM 2637 CD PRO E 348 -6.174 30.279 20.795 1.00 10.73 C ANISOU 2637 CD PRO E 348 1381 1326 1368 -9 -36 -4 C ATOM 2638 N TRP E 349 -4.055 27.343 20.132 1.00 10.65 N ANISOU 2638 N TRP E 349 1385 1312 1348 -13 9 -10 N ATOM 2639 CA TRP E 349 -3.156 26.379 19.492 1.00 10.48 C ANISOU 2639 CA TRP E 349 1311 1290 1378 -26 0 -35 C ATOM 2640 C TRP E 349 -2.042 25.918 20.453 1.00 10.89 C ANISOU 2640 C TRP E 349 1346 1351 1439 -19 2 -51 C ATOM 2641 O TRP E 349 -1.386 24.903 20.204 1.00 11.01 O ANISOU 2641 O TRP E 349 1365 1256 1560 -44 30 -122 O ATOM 2642 CB TRP E 349 -2.575 26.936 18.179 1.00 10.17 C ANISOU 2642 CB TRP E 349 1298 1234 1329 -21 -63 -53 C ATOM 2643 CG TRP E 349 -1.991 28.308 18.316 1.00 8.79 C ANISOU 2643 CG TRP E 349 1051 1125 1163 16 16 -31 C ATOM 2644 CD1 TRP E 349 -2.606 29.493 18.018 1.00 8.01 C ANISOU 2644 CD1 TRP E 349 1033 1069 941 9 6 50 C ATOM 2645 CD2 TRP E 349 -0.697 28.646 18.824 1.00 6.78 C ANISOU 2645 CD2 TRP E 349 926 817 833 45 -16 -56 C ATOM 2646 NE1 TRP E 349 -1.767 30.542 18.297 1.00 8.30 N ANISOU 2646 NE1 TRP E 349 1027 1104 1020 -16 -49 47 N ATOM 2647 CE2 TRP E 349 -0.584 30.046 18.789 1.00 6.84 C ANISOU 2647 CE2 TRP E 349 848 892 857 0 23 -3 C ATOM 2648 CE3 TRP E 349 0.392 27.900 19.274 1.00 6.06 C ANISOU 2648 CE3 TRP E 349 768 804 730 -50 9 -9 C ATOM 2649 CZ2 TRP E 349 0.556 30.712 19.236 1.00 7.57 C ANISOU 2649 CZ2 TRP E 349 956 833 1084 -32 -11 34 C ATOM 2650 CZ3 TRP E 349 1.520 28.559 19.707 1.00 6.11 C ANISOU 2650 CZ3 TRP E 349 715 795 811 -88 63 27 C ATOM 2651 CH2 TRP E 349 1.598 29.947 19.680 1.00 8.36 C ANISOU 2651 CH2 TRP E 349 1079 941 1155 5 -9 39 C ATOM 2652 N LEU E 350 -1.841 26.633 21.572 1.00 11.13 N ANISOU 2652 N LEU E 350 1412 1405 1410 -13 29 -44 N ATOM 2653 CA LEU E 350 -0.834 26.229 22.547 1.00 11.99 C ANISOU 2653 CA LEU E 350 1517 1522 1515 -19 18 -43 C ATOM 2654 C LEU E 350 -1.212 24.893 23.166 1.00 13.83 C ANISOU 2654 C LEU E 350 1769 1729 1753 -19 1 33 C ATOM 2655 O LEU E 350 -0.386 24.216 23.760 1.00 13.27 O ANISOU 2655 O LEU E 350 1552 1714 1773 -105 14 14 O ATOM 2656 CB LEU E 350 -0.648 27.296 23.625 1.00 11.39 C ANISOU 2656 CB LEU E 350 1480 1443 1403 -34 17 -18 C ATOM 2657 CG LEU E 350 0.303 28.421 23.232 1.00 10.29 C ANISOU 2657 CG LEU E 350 1326 1349 1234 2 42 -3 C ATOM 2658 CD1 LEU E 350 0.161 29.603 24.180 1.00 10.24 C ANISOU 2658 CD1 LEU E 350 1252 1311 1326 -31 1 16 C ATOM 2659 CD2 LEU E 350 1.749 27.924 23.181 1.00 10.40 C ANISOU 2659 CD2 LEU E 350 1360 1342 1249 -30 6 -84 C ATOM 2660 N LYS E 351 -2.479 24.522 23.007 1.00 16.73 N ANISOU 2660 N LYS E 351 2064 2094 2197 -37 -12 18 N ATOM 2661 CA LYS E 351 -2.963 23.219 23.437 1.00 18.77 C ANISOU 2661 CA LYS E 351 2368 2337 2427 -27 16 35 C ATOM 2662 C LYS E 351 -2.737 22.165 22.341 1.00 20.26 C ANISOU 2662 C LYS E 351 2571 2503 2624 -8 -11 -13 C ATOM 2663 O LYS E 351 -2.753 20.972 22.625 1.00 21.71 O ANISOU 2663 O LYS E 351 2818 2587 2840 47 -50 32 O ATOM 2664 CB LYS E 351 -4.442 23.305 23.813 1.00 19.28 C ANISOU 2664 CB LYS E 351 2409 2396 2517 -7 3 12 C ATOM 2665 CG LYS E 351 -4.661 23.960 25.166 1.00 20.27 C ANISOU 2665 CG LYS E 351 2602 2534 2562 -4 6 1 C ATOM 2666 CD LYS E 351 -5.966 23.517 25.808 1.00 22.49 C ANISOU 2666 CD LYS E 351 2789 2830 2923 -18 38 31 C ATOM 2667 CE LYS E 351 -5.884 23.560 27.340 1.00 23.88 C ANISOU 2667 CE LYS E 351 3064 3010 2998 26 -17 -18 C ATOM 2668 NZ LYS E 351 -7.151 23.122 28.007 1.00 25.19 N ANISOU 2668 NZ LYS E 351 3220 3131 3219 4 24 48 N ATOM 2669 N HIS E 352 -2.548 22.591 21.096 1.00 21.55 N ANISOU 2669 N HIS E 352 2734 2707 2748 9 -15 0 N ATOM 2670 CA HIS E 352 -2.294 21.645 19.999 1.00 22.44 C ANISOU 2670 CA HIS E 352 2851 2815 2859 18 -4 -17 C ATOM 2671 C HIS E 352 -0.951 20.971 20.273 1.00 22.79 C ANISOU 2671 C HIS E 352 2891 2843 2925 5 -39 -17 C ATOM 2672 O HIS E 352 0.070 21.602 20.506 1.00 22.34 O ANISOU 2672 O HIS E 352 2782 2806 2898 0 10 0 O ATOM 2673 CB HIS E 352 -2.241 22.334 18.622 1.00 22.76 C ANISOU 2673 CB HIS E 352 2900 2868 2881 41 -15 -11 C ATOM 2674 CG HIS E 352 -3.521 23.003 18.203 1.00 23.01 C ANISOU 2674 CG HIS E 352 2890 2924 2929 19 -37 -27 C ATOM 2675 ND1 HIS E 352 -4.584 23.202 19.058 1.00 23.37 N ANISOU 2675 ND1 HIS E 352 2888 3000 2989 -30 -20 8 N ATOM 2676 CD2 HIS E 352 -3.882 23.560 17.021 1.00 22.81 C ANISOU 2676 CD2 HIS E 352 2861 2905 2900 2 -3 -24 C ATOM 2677 CE1 HIS E 352 -5.553 23.833 18.417 1.00 23.90 C ANISOU 2677 CE1 HIS E 352 3026 3034 3020 21 -3 28 C ATOM 2678 NE2 HIS E 352 -5.153 24.062 17.179 1.00 23.35 N ANISOU 2678 NE2 HIS E 352 2909 2978 2985 36 -28 -19 N ATOM 2679 OXT HIS E 352 -0.761 19.758 20.294 1.00 24.28 O ANISOU 2679 OXT HIS E 352 3141 2950 3133 51 -88 29 O TER 2680 HIS E 352 ATOM 2681 N ARG F 17 -0.865 37.390 23.574 1.00 9.76 N ANISOU 2681 N ARG F 17 1166 1258 1282 27 -16 7 N ATOM 2682 CA ARG F 17 0.606 37.283 23.774 1.00 9.96 C ANISOU 2682 CA ARG F 17 1237 1266 1281 15 -13 13 C ATOM 2683 C ARG F 17 0.975 35.998 24.499 1.00 9.07 C ANISOU 2683 C ARG F 17 1128 1166 1150 23 2 -10 C ATOM 2684 O ARG F 17 0.204 35.490 25.312 1.00 9.70 O ANISOU 2684 O ARG F 17 1158 1221 1304 30 14 17 O ATOM 2685 CB ARG F 17 1.125 38.479 24.575 1.00 10.66 C ANISOU 2685 CB ARG F 17 1314 1367 1369 33 -5 -21 C ATOM 2686 CG ARG F 17 1.029 39.800 23.828 1.00 13.39 C ANISOU 2686 CG ARG F 17 1671 1621 1796 5 -6 74 C ATOM 2687 CD ARG F 17 1.825 39.809 22.543 1.00 15.97 C ANISOU 2687 CD ARG F 17 2038 2082 1945 33 56 -50 C ATOM 2688 NE ARG F 17 1.939 41.130 21.941 1.00 18.97 N ANISOU 2688 NE ARG F 17 2496 2260 2451 -12 8 29 N ATOM 2689 CZ ARG F 17 2.929 41.510 21.136 1.00 21.13 C ANISOU 2689 CZ ARG F 17 2636 2675 2715 -21 87 11 C ATOM 2690 NH1 ARG F 17 3.916 40.679 20.841 1.00 21.89 N ANISOU 2690 NH1 ARG F 17 2838 2645 2830 56 88 8 N ATOM 2691 NH2 ARG F 17 2.945 42.743 20.640 1.00 22.26 N ANISOU 2691 NH2 ARG F 17 2832 2782 2842 22 44 75 N ATOM 2692 N HIS F 18 2.113 35.426 24.134 1.00 7.94 N ANISOU 2692 N HIS F 18 1056 1008 952 -5 -4 -53 N ATOM 2693 CA HIS F 18 2.674 34.309 24.861 1.00 7.21 C ANISOU 2693 CA HIS F 18 873 957 908 -1 1 -12 C ATOM 2694 C HIS F 18 4.200 34.386 24.908 1.00 7.36 C ANISOU 2694 C HIS F 18 921 920 952 0 -1 3 C ATOM 2695 O HIS F 18 4.830 35.329 24.402 1.00 7.57 O ANISOU 2695 O HIS F 18 893 1003 980 27 26 17 O ATOM 2696 CB HIS F 18 2.269 33.008 24.158 1.00 7.54 C ANISOU 2696 CB HIS F 18 917 956 991 0 -18 13 C ATOM 2697 CG HIS F 18 2.854 32.875 22.788 1.00 7.11 C ANISOU 2697 CG HIS F 18 814 927 957 21 -48 -46 C ATOM 2698 ND1 HIS F 18 4.091 32.312 22.561 1.00 7.58 N ANISOU 2698 ND1 HIS F 18 835 1001 1043 60 56 -41 N ATOM 2699 CD2 HIS F 18 2.381 33.244 21.572 1.00 6.65 C ANISOU 2699 CD2 HIS F 18 830 788 909 -38 23 -18 C ATOM 2700 CE1 HIS F 18 4.358 32.354 21.266 1.00 8.12 C ANISOU 2700 CE1 HIS F 18 994 1024 1067 67 -19 -20 C ATOM 2701 NE2 HIS F 18 3.341 32.924 20.647 1.00 7.84 N ANISOU 2701 NE2 HIS F 18 1020 1044 914 16 -17 -30 N ATOM 2702 N ARG F 19 4.786 33.374 25.526 1.00 6.67 N ANISOU 2702 N ARG F 19 817 842 875 6 12 22 N ATOM 2703 CA ARG F 19 6.223 33.231 25.540 1.00 6.55 C ANISOU 2703 CA ARG F 19 854 812 820 12 -28 8 C ATOM 2704 C ARG F 19 6.539 31.779 25.235 1.00 6.02 C ANISOU 2704 C ARG F 19 782 773 730 3 -54 -14 C ATOM 2705 O ARG F 19 5.707 31.048 24.670 1.00 6.16 O ANISOU 2705 O ARG F 19 793 751 796 40 -94 2 O ATOM 2706 CB ARG F 19 6.801 33.678 26.890 1.00 6.87 C ANISOU 2706 CB ARG F 19 880 826 903 68 -53 -53 C ATOM 2707 CG ARG F 19 6.423 32.829 28.064 1.00 8.23 C ANISOU 2707 CG ARG F 19 986 1036 1102 11 22 52 C ATOM 2708 CD ARG F 19 6.632 33.542 29.405 1.00 10.09 C ANISOU 2708 CD ARG F 19 1240 1388 1205 10 -9 32 C ATOM 2709 NE ARG F 19 5.870 34.781 29.417 1.00 12.34 N ANISOU 2709 NE ARG F 19 1687 1430 1571 4 53 -53 N ATOM 2710 CZ ARG F 19 4.572 34.847 29.674 1.00 16.30 C ANISOU 2710 CZ ARG F 19 1926 2094 2172 18 64 -24 C ATOM 2711 NH1 ARG F 19 3.888 33.753 30.009 1.00 17.29 N ANISOU 2711 NH1 ARG F 19 2205 2107 2256 15 6 5 N ATOM 2712 NH2 ARG F 19 3.950 36.015 29.635 1.00 18.74 N ANISOU 2712 NH2 ARG F 19 2328 2245 2545 81 29 94 N HETATM 2713 N MLZ F 20 7.775 31.394 25.461 1.00 5.97 N ANISOU 2713 N MLZ F 20 728 772 769 -23 8 -6 N HETATM 2714 CA MLZ F 20 8.240 30.027 25.412 1.00 5.67 C ANISOU 2714 CA MLZ F 20 715 754 683 -12 -2 -50 C HETATM 2715 CB MLZ F 20 9.159 29.785 24.229 1.00 6.32 C ANISOU 2715 CB MLZ F 20 763 830 804 31 31 -50 C HETATM 2716 CG MLZ F 20 8.449 30.058 22.908 1.00 7.42 C ANISOU 2716 CG MLZ F 20 1009 863 945 -41 -119 -65 C HETATM 2717 CD MLZ F 20 9.409 30.028 21.714 1.00 9.80 C ANISOU 2717 CD MLZ F 20 1194 1277 1249 -13 -90 -86 C HETATM 2718 CE MLZ F 20 8.664 30.604 20.512 1.00 11.08 C ANISOU 2718 CE MLZ F 20 1391 1579 1240 50 -94 -38 C HETATM 2719 NZ MLZ F 20 9.438 31.092 19.422 1.00 13.83 N ANISOU 2719 NZ MLZ F 20 1554 1825 1874 -98 -134 135 N HETATM 2720 CM MLZ F 20 8.787 31.732 18.306 1.00 12.90 C ANISOU 2720 CM MLZ F 20 1621 1680 1598 -89 -39 43 C HETATM 2721 C MLZ F 20 8.981 29.774 26.682 1.00 5.95 C ANISOU 2721 C MLZ F 20 677 818 763 28 23 -32 C HETATM 2722 O MLZ F 20 9.604 30.663 27.217 1.00 6.19 O ANISOU 2722 O MLZ F 20 746 772 833 -22 -27 12 O ATOM 2723 N VAL F 21 8.940 28.480 27.193 1.00 5.41 N ANISOU 2723 N VAL F 21 637 631 785 11 5 44 N ATOM 2724 CA VAL F 21 9.540 28.076 28.490 1.00 5.46 C ANISOU 2724 CA VAL F 21 689 702 682 -18 -37 0 C ATOM 2725 C VAL F 21 10.167 26.704 28.332 1.00 6.13 C ANISOU 2725 C VAL F 21 745 723 860 -28 5 11 C ATOM 2726 O VAL F 21 9.514 25.786 27.878 1.00 6.18 O ANISOU 2726 O VAL F 21 815 812 719 56 -154 -69 O ATOM 2727 CB VAL F 21 8.516 28.015 29.616 1.00 5.50 C ANISOU 2727 CB VAL F 21 719 717 654 68 -34 -42 C ATOM 2728 CG1 VAL F 21 9.220 27.607 30.888 1.00 5.98 C ANISOU 2728 CG1 VAL F 21 798 858 614 21 -6 -10 C ATOM 2729 CG2 VAL F 21 7.805 29.334 29.782 1.00 5.77 C ANISOU 2729 CG2 VAL F 21 768 694 728 15 40 43 C ATOM 2730 N LEU F 22 11.467 26.593 28.575 1.00 7.33 N ANISOU 2730 N LEU F 22 902 962 921 -19 -95 -2 N ATOM 2731 CA LEU F 22 12.118 25.297 28.562 1.00 8.38 C ANISOU 2731 CA LEU F 22 1092 1047 1043 -3 -42 -16 C ATOM 2732 C LEU F 22 11.656 24.410 29.721 1.00 10.19 C ANISOU 2732 C LEU F 22 1319 1339 1213 16 -51 24 C ATOM 2733 O LEU F 22 11.746 24.817 30.868 1.00 10.74 O ANISOU 2733 O LEU F 22 1509 1344 1227 127 40 55 O ATOM 2734 CB LEU F 22 13.631 25.472 28.611 1.00 8.54 C ANISOU 2734 CB LEU F 22 1110 1104 1028 14 -38 5 C ATOM 2735 CG LEU F 22 14.431 24.166 28.550 1.00 9.61 C ANISOU 2735 CG LEU F 22 1185 1124 1342 -20 -17 32 C ATOM 2736 CD1 LEU F 22 14.189 23.430 27.263 1.00 10.91 C ANISOU 2736 CD1 LEU F 22 1340 1337 1467 69 17 5 C ATOM 2737 CD2 LEU F 22 15.877 24.449 28.713 1.00 11.21 C ANISOU 2737 CD2 LEU F 22 1320 1412 1526 35 0 37 C ATOM 2738 N ARG F 23 11.180 23.208 29.391 1.00 12.88 N ANISOU 2738 N ARG F 23 1653 1625 1613 11 -3 -12 N ATOM 2739 CA ARG F 23 10.735 22.213 30.356 1.00 15.43 C ANISOU 2739 CA ARG F 23 1939 1945 1976 -31 3 20 C ATOM 2740 C ARG F 23 11.440 20.894 30.057 1.00 18.39 C ANISOU 2740 C ARG F 23 2369 2263 2354 12 35 -15 C ATOM 2741 O ARG F 23 10.968 20.121 29.230 1.00 19.24 O ANISOU 2741 O ARG F 23 2432 2394 2483 56 -10 1 O ATOM 2742 CB ARG F 23 9.231 22.041 30.225 1.00 15.33 C ANISOU 2742 CB ARG F 23 1913 1913 1998 -7 22 -3 C ATOM 2743 CG ARG F 23 8.467 23.251 30.716 1.00 15.68 C ANISOU 2743 CG ARG F 23 1947 1952 2058 -23 16 -20 C ATOM 2744 CD ARG F 23 6.983 23.206 30.445 1.00 15.83 C ANISOU 2744 CD ARG F 23 1979 1962 2074 25 -40 -25 C ATOM 2745 NE ARG F 23 6.333 24.469 30.776 1.00 15.80 N ANISOU 2745 NE ARG F 23 2093 1957 1952 90 19 -8 N ATOM 2746 CZ ARG F 23 6.350 25.045 31.964 1.00 15.65 C ANISOU 2746 CZ ARG F 23 2008 1965 1970 39 -20 -31 C ATOM 2747 NH1 ARG F 23 6.976 24.479 32.992 1.00 16.80 N ANISOU 2747 NH1 ARG F 23 2236 2122 2022 120 19 61 N ATOM 2748 NH2 ARG F 23 5.731 26.205 32.133 1.00 15.17 N ANISOU 2748 NH2 ARG F 23 1940 1909 1913 53 5 72 N ATOM 2749 N ASP F 24 12.559 20.647 30.736 1.00 22.24 N ANISOU 2749 N ASP F 24 2787 2812 2849 15 -32 31 N ATOM 2750 CA ASP F 24 13.417 19.484 30.473 1.00 25.18 C ANISOU 2750 CA ASP F 24 3197 3143 3226 40 34 -4 C ATOM 2751 C ASP F 24 14.667 19.687 31.329 1.00 27.72 C ANISOU 2751 C ASP F 24 3501 3510 3518 29 -34 -11 C ATOM 2752 O ASP F 24 14.680 19.403 32.525 1.00 28.56 O ANISOU 2752 O ASP F 24 3643 3594 3615 47 4 24 O ATOM 2753 CB ASP F 24 13.782 19.482 28.987 1.00 25.59 C ANISOU 2753 CB ASP F 24 3253 3224 3245 44 -1 -4 C ATOM 2754 CG ASP F 24 14.741 18.363 28.591 1.00 25.75 C ANISOU 2754 CG ASP F 24 3243 3246 3292 39 24 24 C ATOM 2755 OD1 ASP F 24 15.971 18.587 28.613 1.00 25.91 O ANISOU 2755 OD1 ASP F 24 3284 3235 3324 43 -96 41 O ATOM 2756 OD2 ASP F 24 14.350 17.254 28.180 1.00 26.30 O ANISOU 2756 OD2 ASP F 24 3324 3336 3330 19 16 14 O ATOM 2757 N ASN F 25 15.708 20.171 30.656 1.00 30.38 N ANISOU 2757 N ASN F 25 3837 3836 3870 1 39 8 N ATOM 2758 CA ASN F 25 16.935 20.746 31.228 1.00 32.13 C ANISOU 2758 CA ASN F 25 4053 4074 4078 -9 -11 -12 C ATOM 2759 C ASN F 25 17.989 20.032 32.079 1.00 33.55 C ANISOU 2759 C ASN F 25 4231 4233 4282 21 -9 10 C ATOM 2760 O ASN F 25 17.799 18.940 32.625 1.00 34.16 O ANISOU 2760 O ASN F 25 4301 4281 4394 8 11 40 O ATOM 2761 CB ASN F 25 16.590 22.048 31.939 1.00 32.50 C ANISOU 2761 CB ASN F 25 4106 4091 4148 11 -24 -16 C ATOM 2762 CG ASN F 25 17.684 23.053 31.792 1.00 33.09 C ANISOU 2762 CG ASN F 25 4188 4189 4194 -6 0 9 C ATOM 2763 OD1 ASN F 25 18.607 22.832 31.008 1.00 34.42 O ANISOU 2763 OD1 ASN F 25 4360 4365 4352 85 29 -15 O ATOM 2764 ND2 ASN F 25 17.615 24.154 32.538 1.00 33.45 N ANISOU 2764 ND2 ASN F 25 4258 4204 4247 -16 37 -8 N ATOM 2765 N TYR F 26 19.112 20.753 32.152 1.00 34.80 N ANISOU 2765 N TYR F 26 4386 4392 4443 -14 4 0 N ATOM 2766 CA TYR F 26 20.359 20.420 32.832 1.00 35.65 C ANISOU 2766 CA TYR F 26 4502 4510 4533 5 -7 3 C ATOM 2767 C TYR F 26 21.436 20.198 31.772 1.00 35.98 C ANISOU 2767 C TYR F 26 4548 4554 4567 4 5 0 C ATOM 2768 O TYR F 26 22.555 20.703 31.887 1.00 36.41 O ANISOU 2768 O TYR F 26 4608 4594 4633 13 11 -1 O ATOM 2769 CB TYR F 26 20.242 19.268 33.830 1.00 35.94 C ANISOU 2769 CB TYR F 26 4548 4533 4571 2 9 13 C ATOM 2770 CG TYR F 26 20.387 19.788 35.238 1.00 36.76 C ANISOU 2770 CG TYR F 26 4668 4652 4644 3 -7 -12 C ATOM 2771 CD1 TYR F 26 19.294 19.879 36.092 1.00 37.37 C ANISOU 2771 CD1 TYR F 26 4723 4748 4727 5 19 -5 C ATOM 2772 CD2 TYR F 26 21.615 20.246 35.693 1.00 37.11 C ANISOU 2772 CD2 TYR F 26 4681 4704 4714 -7 -3 -9 C ATOM 2773 CE1 TYR F 26 19.432 20.387 37.372 1.00 37.70 C ANISOU 2773 CE1 TYR F 26 4788 4778 4757 3 -11 -12 C ATOM 2774 CE2 TYR F 26 21.763 20.754 36.962 1.00 37.47 C ANISOU 2774 CE2 TYR F 26 4740 4764 4732 0 -11 -1 C ATOM 2775 CZ TYR F 26 20.672 20.824 37.799 1.00 37.69 C ANISOU 2775 CZ TYR F 26 4756 4782 4781 3 6 0 C ATOM 2776 OH TYR F 26 20.824 21.324 39.072 1.00 38.06 O ANISOU 2776 OH TYR F 26 4811 4819 4831 11 12 -16 O ATOM 2777 OXT TYR F 26 21.197 19.562 30.744 1.00 36.53 O ANISOU 2777 OXT TYR F 26 4633 4597 4649 -11 15 -12 O TER 2778 TYR F 26 HETATM 2779 N SAH A1354 4.709 4.756 -7.372 1.00 43.87 N ANISOU 2779 N SAH A1354 5545 5710 5414 -108 13 -10 N HETATM 2780 CA SAH A1354 3.701 3.763 -7.776 1.00 45.72 C ANISOU 2780 CA SAH A1354 5788 5869 5714 -84 17 -27 C HETATM 2781 CB SAH A1354 2.590 3.686 -6.734 1.00 45.63 C ANISOU 2781 CB SAH A1354 5703 5828 5806 -50 21 -23 C HETATM 2782 CG SAH A1354 3.005 2.800 -5.568 1.00 46.36 C ANISOU 2782 CG SAH A1354 5710 6121 5782 -40 -65 30 C HETATM 2783 SD SAH A1354 3.045 1.059 -6.070 1.00 45.79 S ANISOU 2783 SD SAH A1354 5488 6197 5711 -231 -14 -20 S HETATM 2784 C SAH A1354 3.121 4.009 -9.171 1.00 46.46 C ANISOU 2784 C SAH A1354 5951 5895 5807 -103 0 -6 C HETATM 2785 O SAH A1354 2.383 3.110 -9.589 1.00 48.75 O ANISOU 2785 O SAH A1354 6168 6297 6056 -171 -83 -118 O HETATM 2786 C5' SAH A1354 4.691 0.600 -5.417 1.00 43.95 C ANISOU 2786 C5' SAH A1354 5469 5741 5486 -175 77 -16 C HETATM 2787 C4' SAH A1354 5.874 1.053 -6.257 1.00 43.94 C ANISOU 2787 C4' SAH A1354 5650 5704 5338 -5 79 25 C HETATM 2788 O4' SAH A1354 6.086 2.432 -6.056 1.00 42.66 O ANISOU 2788 O4' SAH A1354 5119 5735 5351 -164 93 -38 O HETATM 2789 C3' SAH A1354 7.188 0.357 -5.887 1.00 45.30 C ANISOU 2789 C3' SAH A1354 5632 5841 5738 -4 78 -77 C HETATM 2790 O3' SAH A1354 7.309 -0.955 -6.400 1.00 47.15 O ANISOU 2790 O3' SAH A1354 5858 6005 6050 -121 74 -202 O HETATM 2791 C2' SAH A1354 8.158 1.383 -6.420 1.00 44.92 C ANISOU 2791 C2' SAH A1354 5681 5869 5517 -43 -81 -67 C HETATM 2792 O2' SAH A1354 8.293 1.282 -7.835 1.00 47.13 O ANISOU 2792 O2' SAH A1354 5807 6405 5693 -142 182 -209 O HETATM 2793 C1' SAH A1354 7.480 2.681 -6.046 1.00 42.42 C ANISOU 2793 C1' SAH A1354 5187 5739 5192 -166 -53 -82 C HETATM 2794 N9 SAH A1354 7.853 3.160 -4.695 1.00 41.88 N ANISOU 2794 N9 SAH A1354 4940 5809 5161 -213 4 -152 N HETATM 2795 C8 SAH A1354 7.073 3.205 -3.565 1.00 41.92 C ANISOU 2795 C8 SAH A1354 5182 5616 5126 -159 60 -25 C HETATM 2796 N7 SAH A1354 7.760 3.742 -2.551 1.00 41.58 N ANISOU 2796 N7 SAH A1354 4774 5752 5271 -153 250 -125 N HETATM 2797 C5 SAH A1354 9.006 4.065 -3.030 1.00 40.85 C ANISOU 2797 C5 SAH A1354 4813 5513 5194 -254 177 -125 C HETATM 2798 C6 SAH A1354 10.101 4.639 -2.412 1.00 42.77 C ANISOU 2798 C6 SAH A1354 5139 5830 5279 -163 43 -138 C HETATM 2799 N6 SAH A1354 10.129 5.013 -1.129 1.00 44.16 N ANISOU 2799 N6 SAH A1354 5293 5961 5524 -169 95 -173 N HETATM 2800 N1 SAH A1354 11.210 4.823 -3.211 1.00 44.20 N ANISOU 2800 N1 SAH A1354 5227 6137 5429 -195 187 -87 N HETATM 2801 C2 SAH A1354 11.233 4.452 -4.540 1.00 44.80 C ANISOU 2801 C2 SAH A1354 5443 6086 5492 -195 79 -113 C HETATM 2802 N3 SAH A1354 10.155 3.886 -5.172 1.00 43.96 N ANISOU 2802 N3 SAH A1354 5366 5978 5359 -110 149 -124 N HETATM 2803 C4 SAH A1354 9.060 3.709 -4.385 1.00 41.84 C ANISOU 2803 C4 SAH A1354 5002 5621 5275 -196 54 -37 C HETATM 2804 N SAH E1354 4.881 31.596 12.410 1.00 47.72 N ANISOU 2804 N SAH E1354 6051 6075 6005 -65 -4 -39 N HETATM 2805 CA SAH E1354 5.777 32.632 12.945 1.00 48.85 C ANISOU 2805 CA SAH E1354 6250 6180 6129 -69 -1 -25 C HETATM 2806 CB SAH E1354 7.092 32.023 13.375 1.00 49.10 C ANISOU 2806 CB SAH E1354 6269 6199 6184 -66 11 -29 C HETATM 2807 CG SAH E1354 7.011 31.485 14.791 1.00 48.47 C ANISOU 2807 CG SAH E1354 6088 6186 6140 4 1 -28 C HETATM 2808 SD SAH E1354 6.854 32.828 16.001 1.00 49.23 S ANISOU 2808 SD SAH E1354 6306 6480 5917 -355 -160 -170 S HETATM 2809 C SAH E1354 6.014 33.719 11.915 1.00 49.64 C ANISOU 2809 C SAH E1354 6409 6237 6212 -72 -24 -23 C HETATM 2810 O SAH E1354 5.387 33.700 10.855 1.00 50.92 O ANISOU 2810 O SAH E1354 6596 6575 6173 -163 -32 -12 O HETATM 2811 C5' SAH E1354 5.408 32.301 16.971 1.00 46.82 C ANISOU 2811 C5' SAH E1354 6052 5906 5829 19 1 -130 C HETATM 2812 C4' SAH E1354 4.058 32.594 16.338 1.00 46.98 C ANISOU 2812 C4' SAH E1354 6021 5889 5939 -46 41 -126 C HETATM 2813 O4' SAH E1354 3.789 31.671 15.298 1.00 45.22 O ANISOU 2813 O4' SAH E1354 5651 5928 5600 -136 -68 -101 O HETATM 2814 C3' SAH E1354 2.873 32.484 17.291 1.00 47.62 C ANISOU 2814 C3' SAH E1354 5985 6065 6041 29 23 -100 C HETATM 2815 O3' SAH E1354 2.724 33.669 18.045 1.00 48.81 O ANISOU 2815 O3' SAH E1354 6129 6190 6226 -25 -87 -230 O HETATM 2816 C2' SAH E1354 1.739 32.207 16.321 1.00 46.75 C ANISOU 2816 C2' SAH E1354 5978 5834 5948 -25 21 -168 C HETATM 2817 O2' SAH E1354 1.294 33.361 15.641 1.00 48.39 O ANISOU 2817 O2' SAH E1354 6019 6218 6147 81 -84 -133 O HETATM 2818 C1' SAH E1354 2.422 31.316 15.315 1.00 45.56 C ANISOU 2818 C1' SAH E1354 5635 6031 5642 -2 -18 -51 C HETATM 2819 N9 SAH E1354 2.283 29.892 15.661 1.00 44.31 N ANISOU 2819 N9 SAH E1354 5576 5914 5344 -132 -8 -184 N HETATM 2820 C8 SAH E1354 3.243 29.048 16.147 1.00 43.84 C ANISOU 2820 C8 SAH E1354 5689 5670 5294 -39 82 -50 C HETATM 2821 N7 SAH E1354 2.745 27.806 16.330 1.00 44.10 N ANISOU 2821 N7 SAH E1354 5493 5910 5351 -134 124 -82 N HETATM 2822 C5 SAH E1354 1.437 27.843 15.913 1.00 43.41 C ANISOU 2822 C5 SAH E1354 5429 5730 5332 -84 54 -123 C HETATM 2823 C6 SAH E1354 0.447 26.846 15.861 1.00 43.95 C ANISOU 2823 C6 SAH E1354 5499 5736 5461 -36 58 -18 C HETATM 2824 N6 SAH E1354 0.636 25.592 16.235 1.00 43.81 N ANISOU 2824 N6 SAH E1354 5425 5799 5422 -48 94 -276 N HETATM 2825 N1 SAH E1354 -0.776 27.252 15.395 1.00 45.67 N ANISOU 2825 N1 SAH E1354 5623 6077 5652 -7 -8 -47 N HETATM 2826 C2 SAH E1354 -1.016 28.552 15.013 1.00 45.83 C ANISOU 2826 C2 SAH E1354 5631 5969 5814 -75 63 -62 C HETATM 2827 N3 SAH E1354 -0.046 29.527 15.047 1.00 46.32 N ANISOU 2827 N3 SAH E1354 5852 5871 5877 -7 -27 -147 N HETATM 2828 C4 SAH E1354 1.152 29.143 15.499 1.00 44.24 C ANISOU 2828 C4 SAH E1354 5579 5850 5379 -89 45 -140 C HETATM 2829 O HOH A2001 -18.981 10.619 30.055 1.00 60.54 O ANISOU 2829 O HOH A2001 7719 7662 7619 6 18 18 O HETATM 2830 O HOH A2002 -22.188 16.274 34.253 1.00 66.75 O ANISOU 2830 O HOH A2002 8477 8414 8471 2 9 16 O HETATM 2831 O HOH A2003 -16.234 13.312 29.275 1.00 62.79 O ANISOU 2831 O HOH A2003 8028 7911 7919 -19 8 10 O HETATM 2832 O HOH A2004 -22.656 9.819 25.033 1.00 56.80 O ANISOU 2832 O HOH A2004 7201 7183 7196 2 -1 -5 O HETATM 2833 O HOH A2005 -24.254 11.479 31.895 1.00 61.28 O HETATM 2834 O HOH A2006 -20.187 16.936 22.553 1.00 51.83 O ANISOU 2834 O HOH A2006 6432 6633 6628 6 -55 17 O HETATM 2835 O HOH A2007 -22.276 4.376 27.709 1.00 63.66 O ANISOU 2835 O HOH A2007 8053 8068 8065 4 10 -11 O HETATM 2836 O HOH A2008 -23.105 8.079 29.817 1.00 57.84 O ANISOU 2836 O HOH A2008 7356 7325 7295 0 6 0 O HETATM 2837 O HOH A2009 -18.409 6.543 30.050 1.00 55.79 O ANISOU 2837 O HOH A2009 7057 7109 7032 17 -49 0 O HETATM 2838 O HOH A2010 -16.380 8.380 28.648 1.00 68.09 O ANISOU 2838 O HOH A2010 8622 8626 8624 7 -25 -10 O HETATM 2839 O HOH A2011 -19.924 1.149 21.464 1.00 65.29 O ANISOU 2839 O HOH A2011 8297 8263 8246 -3 5 13 O HETATM 2840 O HOH A2012 -19.321 3.330 28.379 1.00 59.32 O ANISOU 2840 O HOH A2012 7562 7513 7462 24 -3 8 O HETATM 2841 O HOH A2013 -15.640 9.205 18.303 1.00 37.91 O ANISOU 2841 O HOH A2013 5130 4631 4640 64 -143 -56 O HETATM 2842 O HOH A2014 -11.829 2.593 22.933 1.00 64.66 O ANISOU 2842 O HOH A2014 8212 8167 8187 22 7 -11 O HETATM 2843 O HOH A2015 -21.286 2.235 15.192 1.00 39.17 O ANISOU 2843 O HOH A2015 4870 5022 4987 8 31 35 O HETATM 2844 O HOH A2016 -23.486 3.723 21.141 1.00 54.92 O ANISOU 2844 O HOH A2016 6965 6937 6963 -1 -4 16 O HETATM 2845 O HOH A2017 -17.237 11.009 18.164 1.00 44.16 O ANISOU 2845 O HOH A2017 5754 5523 5503 -15 -18 -85 O HETATM 2846 O HOH A2018 -20.373 8.807 13.537 1.00 36.49 O ANISOU 2846 O HOH A2018 4897 4465 4501 167 19 26 O HETATM 2847 O HOH A2019 -23.969 11.644 21.101 1.00 44.97 O ANISOU 2847 O HOH A2019 5768 5700 5617 18 4 18 O HETATM 2848 O HOH A2020 -12.132 9.356 13.129 1.00 52.47 O ANISOU 2848 O HOH A2020 6684 6701 6548 70 -55 27 O HETATM 2849 O HOH A2021 -14.988 -1.768 13.331 1.00 60.60 O ANISOU 2849 O HOH A2021 7691 7663 7671 25 -38 19 O HETATM 2850 O HOH A2022 -27.211 6.410 14.919 1.00 49.46 O ANISOU 2850 O HOH A2022 6344 6234 6212 -10 -26 5 O HETATM 2851 O HOH A2023 -17.764 9.709 7.923 1.00 34.92 O ANISOU 2851 O HOH A2023 4667 4269 4329 246 72 66 O HETATM 2852 O HOH A2024 -17.377 13.861 12.571 1.00 64.64 O ANISOU 2852 O HOH A2024 8246 8150 8162 8 -28 0 O HETATM 2853 O HOH A2025 -17.322 -1.595 11.652 1.00 51.73 O ANISOU 2853 O HOH A2025 6545 6536 6573 15 3 3 O HETATM 2854 O HOH A2026 -21.234 1.147 12.523 1.00 45.49 O ANISOU 2854 O HOH A2026 5746 5707 5828 4 -35 31 O HETATM 2855 O HOH A2027 -22.099 1.476 9.854 1.00 47.87 O ANISOU 2855 O HOH A2027 5998 6107 6083 11 -28 9 O HETATM 2856 O HOH A2028 -25.219 8.504 9.306 1.00 54.67 O ANISOU 2856 O HOH A2028 6993 6884 6893 30 -51 -48 O HETATM 2857 O HOH A2029 -19.693 10.472 10.008 1.00 50.79 O ANISOU 2857 O HOH A2029 6417 6447 6431 90 -4 56 O HETATM 2858 O HOH A2030 -21.546 6.150 3.257 1.00 44.68 O ANISOU 2858 O HOH A2030 5597 5709 5667 18 -13 65 O HETATM 2859 O HOH A2031 -20.856 8.693 10.876 1.00 42.34 O ANISOU 2859 O HOH A2031 5537 5395 5153 94 47 17 O HETATM 2860 O HOH A2032 -16.059 2.009 -1.473 1.00 51.36 O ANISOU 2860 O HOH A2032 6558 6543 6412 -16 -14 23 O HETATM 2861 O HOH A2033 -22.706 3.189 -0.248 1.00 45.92 O ANISOU 2861 O HOH A2033 5726 5836 5883 29 -43 26 O HETATM 2862 O HOH A2034 -21.939 2.903 7.361 1.00 62.72 O ANISOU 2862 O HOH A2034 7934 7951 7944 2 -6 20 O HETATM 2863 O HOH A2035 -20.463 0.624 -3.130 1.00 55.22 O ANISOU 2863 O HOH A2035 6953 6990 7038 -69 52 14 O HETATM 2864 O HOH A2036 -17.137 8.239 -4.671 1.00 55.24 O ANISOU 2864 O HOH A2036 6895 7062 7031 22 -17 5 O HETATM 2865 O HOH A2037 -14.044 8.667 -5.786 1.00 64.34 O ANISOU 2865 O HOH A2037 8120 8164 8163 -5 11 20 O HETATM 2866 O HOH A2038 -12.434 10.840 1.801 1.00 39.89 O ANISOU 2866 O HOH A2038 5132 5003 5020 85 138 107 O HETATM 2867 O HOH A2039 -13.162 6.468 1.124 1.00 42.88 O ANISOU 2867 O HOH A2039 5457 5563 5269 63 84 141 O HETATM 2868 O HOH A2040 -8.133 3.739 -2.523 1.00 26.16 O ANISOU 2868 O HOH A2040 3404 3341 3194 -62 99 -37 O HETATM 2869 O HOH A2041 -11.074 5.148 0.253 1.00 31.37 O ANISOU 2869 O HOH A2041 3937 4014 3968 127 -66 169 O HETATM 2870 O HOH A2042 -9.352 13.905 -3.457 1.00 42.76 O ANISOU 2870 O HOH A2042 5151 5539 5556 -22 -49 -52 O HETATM 2871 O HOH A2043 -13.554 11.053 -3.828 1.00 56.35 O ANISOU 2871 O HOH A2043 7078 7055 7278 17 108 38 O HETATM 2872 O HOH A2044 -10.261 8.077 -6.197 1.00 41.92 O ANISOU 2872 O HOH A2044 5345 5354 5229 60 82 11 O HETATM 2873 O HOH A2045 -18.264 15.195 -0.792 1.00 67.88 O ANISOU 2873 O HOH A2045 8592 8617 8583 -5 24 11 O HETATM 2874 O HOH A2046 -14.534 12.506 2.995 1.00 62.18 O ANISOU 2874 O HOH A2046 7893 7835 7897 8 32 -24 O HETATM 2875 O HOH A2047 -13.536 14.121 4.372 1.00 63.30 O ANISOU 2875 O HOH A2047 7968 8042 8041 7 -1 13 O HETATM 2876 O HOH A2048 -15.510 17.972 -2.600 1.00 68.93 O ANISOU 2876 O HOH A2048 8725 8729 8736 3 -6 7 O HETATM 2877 O HOH A2049 -10.889 18.344 0.318 1.00 57.21 O ANISOU 2877 O HOH A2049 7257 7217 7261 -17 -46 1 O HETATM 2878 O HOH A2050 -10.810 16.827 -2.546 1.00 43.95 O ANISOU 2878 O HOH A2050 5452 5558 5689 86 -37 78 O HETATM 2879 O HOH A2051 -7.747 17.235 -6.070 1.00 61.43 O ANISOU 2879 O HOH A2051 7773 7816 7749 -14 1 23 O HETATM 2880 O HOH A2052 -2.245 20.432 -6.850 1.00 66.58 O ANISOU 2880 O HOH A2052 8440 8393 8463 -15 -3 10 O HETATM 2881 O HOH A2053 -5.371 13.456 -8.851 1.00 38.12 O ANISOU 2881 O HOH A2053 4697 4987 4800 192 -255 -179 O HETATM 2882 O HOH A2054 -3.262 15.232 -10.618 1.00 54.16 O ANISOU 2882 O HOH A2054 6807 6851 6920 33 0 10 O HETATM 2883 O HOH A2055 0.248 13.749 -12.352 1.00 66.06 O ANISOU 2883 O HOH A2055 8336 8408 8356 16 0 9 O HETATM 2884 O HOH A2056 6.904 16.366 -6.628 1.00 52.74 O ANISOU 2884 O HOH A2056 6708 6622 6706 43 -5 56 O HETATM 2885 O HOH A2057 4.911 19.121 -8.735 1.00 54.04 O ANISOU 2885 O HOH A2057 6919 6809 6801 31 27 13 O HETATM 2886 O HOH A2058 2.514 17.442 -12.852 1.00 64.07 O ANISOU 2886 O HOH A2058 8096 8140 8107 10 -14 7 O HETATM 2887 O HOH A2059 13.182 8.860 -4.198 1.00 48.32 O ANISOU 2887 O HOH A2059 6201 6023 6135 -11 -49 67 O HETATM 2888 O HOH A2060 9.306 15.068 -6.341 1.00 38.32 O ANISOU 2888 O HOH A2060 4913 4664 4982 7 30 -86 O HETATM 2889 O HOH A2061 16.837 14.800 -7.683 1.00 63.19 O ANISOU 2889 O HOH A2061 8028 7990 7990 7 -17 3 O HETATM 2890 O HOH A2062 13.940 16.554 -7.278 1.00 52.87 O ANISOU 2890 O HOH A2062 6764 6585 6739 -34 -26 -32 O HETATM 2891 O HOH A2063 11.420 11.860 -3.779 1.00 40.54 O ANISOU 2891 O HOH A2063 5515 5124 4763 -51 -209 -209 O HETATM 2892 O HOH A2064 14.414 14.766 -5.068 1.00 55.00 O ANISOU 2892 O HOH A2064 6977 6940 6981 -34 -46 -66 O HETATM 2893 O HOH A2065 13.686 4.866 -7.636 1.00 55.37 O ANISOU 2893 O HOH A2065 6937 6972 7125 8 21 13 O HETATM 2894 O HOH A2066 -2.372 7.520 -12.378 1.00 37.05 O ANISOU 2894 O HOH A2066 4823 4834 4419 -7 -31 93 O HETATM 2895 O HOH A2067 -1.618 20.775 -2.304 1.00 49.68 O ANISOU 2895 O HOH A2067 6244 6372 6260 -19 -18 73 O HETATM 2896 O HOH A2068 -9.060 19.638 -0.411 1.00 50.65 O ANISOU 2896 O HOH A2068 6431 6431 6382 77 -11 32 O HETATM 2897 O HOH A2069 -8.221 17.587 -3.752 1.00 48.81 O ANISOU 2897 O HOH A2069 6134 6246 6164 -61 -38 -28 O HETATM 2898 O HOH A2070 -8.725 19.607 6.622 1.00 51.09 O ANISOU 2898 O HOH A2070 6405 6554 6450 9 65 -15 O HETATM 2899 O HOH A2071 -7.059 22.181 5.092 1.00 42.21 O ANISOU 2899 O HOH A2071 5392 5038 5607 109 -9 -48 O HETATM 2900 O HOH A2072 -1.828 19.999 9.676 1.00 58.10 O ANISOU 2900 O HOH A2072 7458 7289 7327 45 29 -8 O HETATM 2901 O HOH A2073 -2.194 22.817 12.001 1.00 60.57 O ANISOU 2901 O HOH A2073 7674 7692 7648 -59 -3 30 O HETATM 2902 O HOH A2074 -4.713 19.180 11.801 1.00 66.06 O ANISOU 2902 O HOH A2074 8402 8347 8351 21 18 -19 O HETATM 2903 O HOH A2075 0.777 8.123 15.749 1.00 62.80 O ANISOU 2903 O HOH A2075 7978 7959 7923 -22 -8 22 O HETATM 2904 O HOH A2076 -6.255 14.784 16.129 1.00 37.11 O ANISOU 2904 O HOH A2076 4773 4613 4714 104 104 -139 O HETATM 2905 O HOH A2077 -3.000 8.846 18.387 1.00 61.38 O ANISOU 2905 O HOH A2077 7856 7732 7733 -1 10 -19 O HETATM 2906 O HOH A2078 -10.313 7.678 11.927 1.00 64.06 O ANISOU 2906 O HOH A2078 8046 8152 8142 -17 26 -3 O HETATM 2907 O HOH A2079 -10.638 14.903 13.019 1.00 61.08 O ANISOU 2907 O HOH A2079 7677 7753 7774 4 24 -18 O HETATM 2908 O HOH A2080 -9.958 14.797 7.771 1.00 44.64 O ANISOU 2908 O HOH A2080 5756 5484 5721 89 -49 -17 O HETATM 2909 O HOH A2081 -8.700 12.714 14.198 1.00 42.55 O ANISOU 2909 O HOH A2081 5426 5490 5248 58 -30 -54 O HETATM 2910 O HOH A2082 -9.323 17.223 10.719 1.00 62.87 O ANISOU 2910 O HOH A2082 8021 7939 7926 19 -3 26 O HETATM 2911 O HOH A2083 -10.713 12.244 7.120 1.00 38.79 O ANISOU 2911 O HOH A2083 4867 4751 5119 280 -22 -69 O HETATM 2912 O HOH A2084 -11.648 10.130 10.313 1.00 38.40 O ANISOU 2912 O HOH A2084 4607 5129 4854 118 60 -16 O HETATM 2913 O HOH A2085 -9.906 11.376 2.603 1.00 35.80 O ANISOU 2913 O HOH A2085 4653 4405 4542 254 74 123 O HETATM 2914 O HOH A2086 -13.376 2.995 0.200 1.00 35.10 O ANISOU 2914 O HOH A2086 4378 4522 4435 150 154 39 O HETATM 2915 O HOH A2087 -14.738 -1.056 0.140 1.00 39.11 O ANISOU 2915 O HOH A2087 4965 4973 4922 -62 2 -22 O HETATM 2916 O HOH A2088 -9.278 -2.957 1.804 1.00 25.92 O ANISOU 2916 O HOH A2088 3344 3147 3355 26 145 -6 O HETATM 2917 O HOH A2089 -12.149 -3.098 -1.172 1.00 57.43 O ANISOU 2917 O HOH A2089 7404 7176 7240 -15 -49 4 O HETATM 2918 O HOH A2090 -12.750 -4.301 -5.728 1.00 57.28 O ANISOU 2918 O HOH A2090 7324 7246 7191 3 -16 -17 O HETATM 2919 O HOH A2091 -13.082 -4.886 -3.192 1.00 60.31 O ANISOU 2919 O HOH A2091 7629 7661 7624 28 -29 30 O HETATM 2920 O HOH A2092 -6.748 -5.817 -8.533 1.00 37.31 O ANISOU 2920 O HOH A2092 4648 4940 4586 -88 -59 95 O HETATM 2921 O HOH A2093 -9.498 -7.079 -10.332 1.00 63.71 O ANISOU 2921 O HOH A2093 8050 8093 8063 -17 2 27 O HETATM 2922 O HOH A2094 -8.218 -9.128 -10.106 1.00 61.89 O ANISOU 2922 O HOH A2094 7818 7904 7791 21 24 25 O HETATM 2923 O HOH A2095 -12.793 -7.273 -2.559 1.00 43.84 O ANISOU 2923 O HOH A2095 5503 5655 5497 54 52 53 O HETATM 2924 O HOH A2096 -12.332 -11.609 -4.609 1.00 60.21 O ANISOU 2924 O HOH A2096 7611 7607 7658 33 -9 16 O HETATM 2925 O HOH A2097 -9.112 -16.256 -2.713 1.00 31.65 O ANISOU 2925 O HOH A2097 3836 3946 4242 -154 -4 -24 O HETATM 2926 O HOH A2098 -12.601 -17.282 1.685 1.00 64.04 O ANISOU 2926 O HOH A2098 8123 8118 8090 16 3 4 O HETATM 2927 O HOH A2099 -13.116 -18.575 -1.921 1.00 63.11 O ANISOU 2927 O HOH A2099 7986 7991 8001 16 -9 3 O HETATM 2928 O HOH A2100 -6.681 -20.705 -4.557 1.00 54.53 O ANISOU 2928 O HOH A2100 6912 6931 6875 -3 0 -4 O HETATM 2929 O HOH A2101 -5.761 -19.757 0.950 1.00 47.96 O ANISOU 2929 O HOH A2101 6033 6087 6101 -5 11 -6 O HETATM 2930 O HOH A2102 -0.596 -21.029 -3.779 1.00 45.64 O ANISOU 2930 O HOH A2102 5862 5636 5840 63 51 12 O HETATM 2931 O HOH A2103 -4.411 -17.171 -8.224 1.00 55.22 O ANISOU 2931 O HOH A2103 6947 7014 7017 13 19 -11 O HETATM 2932 O HOH A2104 -8.186 -15.947 -7.856 1.00 62.91 O ANISOU 2932 O HOH A2104 7985 7954 7962 13 16 4 O HETATM 2933 O HOH A2105 -19.044 16.703 35.924 1.00 55.56 O ANISOU 2933 O HOH A2105 7055 7023 7030 -6 50 7 O HETATM 2934 O HOH A2106 -21.541 11.857 32.512 1.00 64.71 O ANISOU 2934 O HOH A2106 8199 8194 8193 2 -1 0 O HETATM 2935 O HOH A2107 5.586 -17.799 -1.130 1.00 63.78 O ANISOU 2935 O HOH A2107 8126 8096 8011 -4 -25 -14 O HETATM 2936 O HOH A2108 4.476 -16.166 -5.174 1.00 47.16 O ANISOU 2936 O HOH A2108 5980 5963 5976 40 5 25 O HETATM 2937 O HOH A2109 -17.665 4.851 33.382 1.00 58.28 O ANISOU 2937 O HOH A2109 7399 7378 7364 8 -20 -21 O HETATM 2938 O HOH A2110 -2.596 -25.010 -4.246 1.00 58.82 O ANISOU 2938 O HOH A2110 7394 7391 7562 19 58 25 O HETATM 2939 O HOH A2111 -4.808 -25.260 -5.239 1.00 68.00 O ANISOU 2939 O HOH A2111 8626 8576 8631 -12 6 24 O HETATM 2940 O HOH A2112 -7.195 -11.747 -11.240 1.00 65.04 O ANISOU 2940 O HOH A2112 8263 8208 8241 -13 6 20 O HETATM 2941 O HOH A2113 -11.098 -12.044 -6.945 1.00 49.91 O ANISOU 2941 O HOH A2113 6263 6367 6332 -25 2 -7 O HETATM 2942 O HOH A2114 -21.186 -0.093 14.949 1.00 68.36 O ANISOU 2942 O HOH A2114 8686 8626 8662 -12 1 -1 O HETATM 2943 O HOH A2115 5.940 -9.818 -5.467 1.00 38.77 O ANISOU 2943 O HOH A2115 4871 4962 4897 -73 12 -77 O HETATM 2944 O HOH A2116 4.972 -10.210 -8.113 1.00 39.95 O ANISOU 2944 O HOH A2116 5007 5193 4979 70 165 42 O HETATM 2945 O HOH A2117 -18.772 10.466 5.499 1.00 43.77 O ANISOU 2945 O HOH A2117 5677 5521 5431 61 -14 86 O HETATM 2946 O HOH A2118 -15.995 11.768 8.222 1.00 49.52 O ANISOU 2946 O HOH A2118 6410 6210 6195 94 15 21 O HETATM 2947 O HOH A2119 -18.019 10.302 -5.638 1.00 59.91 O ANISOU 2947 O HOH A2119 7604 7583 7575 11 -26 7 O HETATM 2948 O HOH A2120 -16.334 9.988 -7.235 1.00 56.37 O ANISOU 2948 O HOH A2120 7153 7192 7071 2 -38 -3 O HETATM 2949 O HOH A2121 -5.102 -8.201 -11.306 1.00 56.19 O ANISOU 2949 O HOH A2121 7011 7137 7199 -8 -31 -8 O HETATM 2950 O HOH A2122 -11.162 12.883 4.485 1.00 44.76 O ANISOU 2950 O HOH A2122 5778 5646 5582 58 16 -25 O HETATM 2951 O HOH A2123 -11.777 14.634 -4.598 1.00 56.26 O ANISOU 2951 O HOH A2123 7126 7117 7132 5 6 13 O HETATM 2952 O HOH A2124 -9.759 10.474 -6.599 1.00 67.05 O ANISOU 2952 O HOH A2124 8501 8465 8508 -8 1 0 O HETATM 2953 O HOH A2125 10.641 -11.536 -11.789 1.00 56.69 O ANISOU 2953 O HOH A2125 7181 7206 7152 -28 -3 32 O HETATM 2954 O HOH A2126 -16.002 12.951 5.589 1.00 60.90 O ANISOU 2954 O HOH A2126 7733 7643 7762 -1 0 19 O HETATM 2955 O HOH A2127 3.167 -18.372 -12.853 1.00 58.02 O ANISOU 2955 O HOH A2127 7343 7377 7324 -3 -9 -9 O HETATM 2956 O HOH A2128 6.706 15.812 -3.643 1.00 58.24 O ANISOU 2956 O HOH A2128 7486 7299 7342 -18 1 2 O HETATM 2957 O HOH A2129 8.924 -15.866 -15.190 1.00 49.99 O ANISOU 2957 O HOH A2129 6336 6318 6339 4 -10 19 O HETATM 2958 O HOH A2130 0.728 -5.019 -16.997 1.00 62.08 O ANISOU 2958 O HOH A2130 7865 7832 7889 -1 -23 -12 O HETATM 2959 O HOH A2131 13.086 9.489 -0.617 1.00 64.16 O ANISOU 2959 O HOH A2131 8109 8075 8191 -33 32 -9 O HETATM 2960 O HOH A2132 9.887 14.323 -3.706 1.00 49.77 O ANISOU 2960 O HOH A2132 6203 6363 6343 0 14 -33 O HETATM 2961 O HOH A2133 10.824 17.136 -7.157 1.00 51.96 O ANISOU 2961 O HOH A2133 6625 6498 6619 24 12 34 O HETATM 2962 O HOH A2134 11.952 15.172 -3.966 1.00 58.01 O ANISOU 2962 O HOH A2134 7386 7320 7333 -9 7 0 O HETATM 2963 O HOH A2135 14.063 13.101 -2.887 1.00 57.64 O ANISOU 2963 O HOH A2135 7395 7264 7240 3 -23 -29 O HETATM 2964 O HOH A2136 14.411 15.514 -2.620 1.00 69.71 O ANISOU 2964 O HOH A2136 8825 8824 8838 -3 -8 15 O HETATM 2965 O HOH A2137 9.521 -4.204 -13.849 1.00 65.57 O ANISOU 2965 O HOH A2137 8296 8262 8355 22 -16 -48 O HETATM 2966 O HOH A2138 5.381 -1.885 -20.477 1.00 36.58 O ANISOU 2966 O HOH A2138 4523 4636 4738 -34 -29 115 O HETATM 2967 O HOH A2139 6.013 -3.750 -22.586 1.00 47.95 O ANISOU 2967 O HOH A2139 6148 6100 5970 21 46 103 O HETATM 2968 O HOH A2140 -0.035 -8.928 -15.104 1.00 62.59 O ANISOU 2968 O HOH A2140 7966 7918 7896 -21 4 0 O HETATM 2969 O HOH A2141 1.257 20.851 -3.951 1.00 55.90 O ANISOU 2969 O HOH A2141 7097 7067 7076 -10 -14 -4 O HETATM 2970 O HOH A2142 0.007 23.443 -1.854 1.00 61.50 O ANISOU 2970 O HOH A2142 7747 7845 7774 -20 18 -11 O HETATM 2971 O HOH A2143 -9.146 22.696 3.232 1.00 55.08 O ANISOU 2971 O HOH A2143 7040 6913 6972 45 6 13 O HETATM 2972 O HOH A2144 3.017 -4.414 -2.769 1.00 39.27 O ANISOU 2972 O HOH A2144 4922 5146 4850 18 -16 46 O HETATM 2973 O HOH A2145 4.612 0.338 -10.164 1.00 44.76 O ANISOU 2973 O HOH A2145 5774 5595 5636 -11 -59 -20 O HETATM 2974 O HOH A2146 -11.355 18.154 9.619 1.00 62.90 O ANISOU 2974 O HOH A2146 7992 7954 7952 19 42 -1 O HETATM 2975 O HOH A2147 -13.217 11.849 8.908 1.00 50.37 O ANISOU 2975 O HOH A2147 6501 6255 6381 41 -54 -9 O HETATM 2976 O HOH A2148 2.325 -2.279 6.391 1.00 29.51 O ANISOU 2976 O HOH A2148 3483 3787 3942 -174 33 120 O HETATM 2977 O HOH A2149 -17.337 -0.994 0.792 1.00 51.44 O ANISOU 2977 O HOH A2149 6514 6543 6485 27 -39 18 O HETATM 2978 O HOH A2150 -10.205 -5.349 0.316 1.00 40.25 O ANISOU 2978 O HOH A2150 5069 4926 5297 -2 -78 -115 O HETATM 2979 O HOH A2151 -15.665 -5.721 -5.694 1.00 58.06 O ANISOU 2979 O HOH A2151 7335 7354 7370 26 -14 9 O HETATM 2980 O HOH A2152 -13.768 -3.378 -7.623 1.00 53.28 O ANISOU 2980 O HOH A2152 6704 6760 6779 -14 26 13 O HETATM 2981 O HOH A2153 -16.298 -5.307 -3.136 1.00 61.50 O ANISOU 2981 O HOH A2153 7802 7803 7762 25 36 16 O HETATM 2982 O HOH A2154 -13.969 -6.912 -0.127 1.00 47.67 O ANISOU 2982 O HOH A2154 6021 6092 5998 94 -11 60 O HETATM 2983 O HOH A2155 -16.740 -13.472 -3.972 1.00 59.25 O ANISOU 2983 O HOH A2155 7518 7531 7460 32 -2 0 O HETATM 2984 O HOH A2156 -16.318 -12.573 -6.394 1.00 58.16 O ANISOU 2984 O HOH A2156 7358 7350 7390 -11 -12 0 O HETATM 2985 O HOH A2157 -1.901 -8.550 9.858 1.00 31.83 O ANISOU 2985 O HOH A2157 4070 3974 4047 -170 -15 0 O HETATM 2986 O HOH A2158 -0.798 -10.829 13.189 1.00 65.56 O ANISOU 2986 O HOH A2158 8301 8282 8327 -3 -1 -23 O HETATM 2987 O HOH A2159 -0.621 -14.417 14.490 1.00 38.96 O ANISOU 2987 O HOH A2159 4812 4853 5135 146 -24 49 O HETATM 2988 O HOH A2160 -4.394 -7.589 10.419 1.00 43.49 O ANISOU 2988 O HOH A2160 5401 5540 5581 -52 72 -17 O HETATM 2989 O HOH A2161 -4.284 -14.817 11.470 1.00 45.13 O ANISOU 2989 O HOH A2161 5666 5755 5725 6 22 1 O HETATM 2990 O HOH A2162 -9.167 -18.803 -2.900 1.00 60.41 O ANISOU 2990 O HOH A2162 7699 7614 7640 31 -5 20 O HETATM 2991 O HOH A2163 -14.263 -15.714 2.805 1.00 65.39 O ANISOU 2991 O HOH A2163 8314 8258 8271 3 -16 2 O HETATM 2992 O HOH A2164 -4.151 -20.148 -10.566 1.00 58.88 O ANISOU 2992 O HOH A2164 7463 7467 7442 -6 0 18 O HETATM 2993 O HOH A2165 -17.104 14.147 37.060 1.00 58.20 O ANISOU 2993 O HOH A2165 7318 7369 7424 3 -7 -8 O HETATM 2994 O HOH A2166 -23.980 8.177 32.727 1.00 60.19 O ANISOU 2994 O HOH A2166 7624 7622 7623 0 1 0 O HETATM 2995 O HOH A2167 -21.675 4.866 36.052 1.00 44.95 O ANISOU 2995 O HOH A2167 5689 5622 5768 -7 -73 -15 O HETATM 2996 O HOH A2168 -8.535 -10.763 13.364 1.00 45.45 O ANISOU 2996 O HOH A2168 5939 5750 5578 69 41 -58 O HETATM 2997 O HOH A2169 -10.901 -17.707 9.249 1.00 52.14 O ANISOU 2997 O HOH A2169 6521 6629 6661 -12 13 16 O HETATM 2998 O HOH A2170 -8.197 -14.584 -11.661 1.00 69.62 O ANISOU 2998 O HOH A2170 8829 8856 8764 20 1 -5 O HETATM 2999 O HOH A2171 -4.623 -12.858 -12.033 1.00 61.16 O ANISOU 2999 O HOH A2171 7720 7775 7740 2 1 18 O HETATM 3000 O HOH A2172 -18.277 12.693 4.754 1.00 52.50 O ANISOU 3000 O HOH A2172 6636 6683 6628 -9 4 22 O HETATM 3001 O HOH A2173 -4.968 -18.576 15.946 1.00 66.49 O ANISOU 3001 O HOH A2173 8409 8419 8435 13 -34 15 O HETATM 3002 O HOH A2174 -5.058 -20.686 10.892 1.00 45.01 O ANISOU 3002 O HOH A2174 5658 5705 5737 60 -54 1 O HETATM 3003 O HOH A2175 -5.857 -13.397 13.295 1.00 48.32 O ANISOU 3003 O HOH A2175 6059 6138 6160 10 63 1 O HETATM 3004 O HOH A2176 -8.904 12.943 -6.981 1.00 65.84 O ANISOU 3004 O HOH A2176 8381 8344 8289 35 18 30 O HETATM 3005 O HOH A2177 -9.722 12.608 -10.164 1.00 58.12 O ANISOU 3005 O HOH A2177 7380 7360 7343 -2 6 11 O HETATM 3006 O HOH A2178 -9.286 -20.764 4.038 1.00 67.99 O ANISOU 3006 O HOH A2178 8601 8614 8614 4 10 0 O HETATM 3007 O HOH A2179 -15.302 15.659 7.710 1.00 63.48 O ANISOU 3007 O HOH A2179 8071 8044 8005 -31 11 6 O HETATM 3008 O HOH A2180 14.439 -14.197 -10.246 1.00 53.41 O ANISOU 3008 O HOH A2180 6802 6755 6735 17 -15 -12 O HETATM 3009 O HOH A2181 0.890 -15.018 6.621 1.00 36.44 O ANISOU 3009 O HOH A2181 4345 4807 4691 86 -111 38 O HETATM 3010 O HOH A2182 -6.075 -17.919 4.060 1.00 40.62 O ANISOU 3010 O HOH A2182 5115 5008 5308 -111 -29 -48 O HETATM 3011 O HOH A2183 1.921 22.085 -6.547 1.00 61.78 O ANISOU 3011 O HOH A2183 7879 7830 7763 30 -17 -11 O HETATM 3012 O HOH A2184 -10.900 -15.396 8.627 1.00 50.53 O ANISOU 3012 O HOH A2184 6395 6464 6340 22 9 -13 O HETATM 3013 O HOH A2185 -3.370 -11.244 14.265 1.00 52.85 O ANISOU 3013 O HOH A2185 6727 6767 6584 30 24 -16 O HETATM 3014 O HOH A2186 -8.998 -12.521 15.729 1.00 58.87 O ANISOU 3014 O HOH A2186 7458 7440 7469 20 10 4 O HETATM 3015 O HOH A2187 -17.223 -16.562 3.740 1.00 67.66 O ANISOU 3015 O HOH A2187 8560 8587 8559 6 -33 4 O HETATM 3016 O HOH A2188 -15.436 -13.875 1.170 1.00 69.12 O ANISOU 3016 O HOH A2188 8768 8734 8760 -2 1 10 O HETATM 3017 O HOH A2189 -3.333 -11.588 -15.050 1.00 61.68 O ANISOU 3017 O HOH A2189 7791 7797 7848 3 -22 21 O HETATM 3018 O HOH A2190 -15.237 12.868 39.005 1.00 60.42 O ANISOU 3018 O HOH A2190 7695 7610 7651 9 23 14 O HETATM 3019 O HOH A2191 -14.752 13.957 36.037 1.00 64.97 O ANISOU 3019 O HOH A2191 8225 8231 8227 -6 11 1 O HETATM 3020 O HOH A2192 -2.778 -22.689 -14.084 1.00 50.95 O ANISOU 3020 O HOH A2192 6495 6477 6387 28 5 14 O HETATM 3021 O HOH A2193 -4.611 -20.336 -13.942 1.00 54.30 O ANISOU 3021 O HOH A2193 6869 6920 6841 13 29 1 O HETATM 3022 O HOH A2194 -5.872 -18.879 -14.359 1.00 46.67 O ANISOU 3022 O HOH A2194 5925 5905 5901 15 -40 -19 O HETATM 3023 O HOH A2195 -9.263 15.439 -11.701 1.00 73.67 O ANISOU 3023 O HOH A2195 9337 9293 9360 -5 3 -7 O HETATM 3024 O HOH A2196 15.563 -16.429 -11.094 1.00 48.25 O ANISOU 3024 O HOH A2196 5973 6130 6229 -5 31 25 O HETATM 3025 O HOH A2197 1.126 -6.805 -8.009 1.00 26.54 O ANISOU 3025 O HOH A2197 3190 3304 3589 43 84 39 O HETATM 3026 O HOH A2198 -11.405 -0.457 -13.267 1.00 56.55 O ANISOU 3026 O HOH A2198 7171 7200 7115 11 -1 -6 O HETATM 3027 O HOH A2199 -6.855 -2.525 -8.019 1.00 31.88 O ANISOU 3027 O HOH A2199 3967 4088 4054 99 13 197 O HETATM 3028 O HOH A2200 -15.657 4.667 -12.127 1.00 52.36 O ANISOU 3028 O HOH A2200 6574 6559 6758 -27 39 2 O HETATM 3029 O HOH A2201 -18.403 -14.339 2.371 1.00 54.86 O ANISOU 3029 O HOH A2201 6986 6931 6925 -8 3 -3 O HETATM 3030 O HOH A2202 -15.657 0.770 -10.954 1.00 59.32 O ANISOU 3030 O HOH A2202 7468 7505 7563 7 7 25 O HETATM 3031 O HOH A2203 -8.211 -7.752 -14.970 1.00 64.71 O ANISOU 3031 O HOH A2203 8237 8225 8123 5 21 -12 O HETATM 3032 O HOH A2204 -10.962 -6.987 -15.692 1.00 67.06 O ANISOU 3032 O HOH A2204 8528 8460 8488 -15 10 14 O HETATM 3033 O HOH A2205 -13.368 -8.105 -14.238 1.00 65.78 O ANISOU 3033 O HOH A2205 8328 8307 8358 0 20 14 O HETATM 3034 O HOH A2206 -14.191 -9.399 -10.259 1.00 63.93 O ANISOU 3034 O HOH A2206 8075 8080 8133 -13 2 -5 O HETATM 3035 O HOH A2207 -12.197 -9.766 -12.543 1.00 60.62 O ANISOU 3035 O HOH A2207 7667 7630 7736 -3 9 12 O HETATM 3036 O HOH A2208 -9.547 -1.051 -14.981 1.00 70.93 O ANISOU 3036 O HOH A2208 8982 9015 8952 1 -7 26 O HETATM 3037 O HOH A2209 -0.004 -1.054 -13.585 1.00 38.50 O ANISOU 3037 O HOH A2209 5018 4957 4652 47 135 75 O HETATM 3038 O HOH A2210 -4.477 -3.019 -14.898 1.00 42.02 O ANISOU 3038 O HOH A2210 5481 5323 5159 85 49 -52 O HETATM 3039 O HOH A2211 -15.688 5.071 -9.709 1.00 55.80 O ANISOU 3039 O HOH A2211 6974 7124 7101 24 0 29 O HETATM 3040 O HOH A2212 -4.825 6.163 -11.105 1.00 40.85 O ANISOU 3040 O HOH A2212 5135 5087 5297 -30 -30 158 O HETATM 3041 O HOH A2213 -8.085 -0.616 -6.776 1.00 37.65 O ANISOU 3041 O HOH A2213 4793 4809 4701 47 37 132 O HETATM 3042 O HOH A2214 -12.273 0.403 -8.440 1.00 54.23 O ANISOU 3042 O HOH A2214 6842 6895 6867 0 4 10 O HETATM 3043 O HOH A2215 -13.280 7.012 -8.872 1.00 64.50 O ANISOU 3043 O HOH A2215 8161 8144 8202 -29 -19 0 O HETATM 3044 O HOH A2216 -6.364 7.113 -9.014 1.00 66.40 O ANISOU 3044 O HOH A2216 8395 8405 8427 -18 -15 -12 O HETATM 3045 O HOH A2217 -7.405 8.524 -10.691 1.00 56.13 O ANISOU 3045 O HOH A2217 7067 7087 7170 -30 -17 -4 O HETATM 3046 O HOH A2218 -12.101 4.219 -8.785 1.00 49.56 O ANISOU 3046 O HOH A2218 6201 6390 6235 74 -69 23 O HETATM 3047 O HOH A2219 -11.697 2.584 -11.769 1.00 52.59 O ANISOU 3047 O HOH A2219 6522 6735 6722 7 -21 -3 O HETATM 3048 O HOH A2220 -4.975 4.044 -9.074 1.00 27.86 O ANISOU 3048 O HOH A2220 3408 3628 3550 114 16 43 O HETATM 3049 O HOH A2221 15.682 -4.148 7.235 1.00 54.72 O ANISOU 3049 O HOH A2221 6957 6876 6956 29 -28 21 O HETATM 3050 O HOH A2222 6.530 4.172 13.096 1.00 68.89 O ANISOU 3050 O HOH A2222 8722 8725 8726 3 22 16 O HETATM 3051 O HOH A2223 23.102 -9.415 0.563 1.00 64.04 O ANISOU 3051 O HOH A2223 8138 8070 8122 9 -15 -5 O HETATM 3052 O HOH A2224 -3.311 7.670 -5.766 1.00 75.36 O ANISOU 3052 O HOH A2224 9569 9540 9522 -9 14 7 O HETATM 3053 O HOH A2225 -6.591 1.662 -3.666 1.00 26.26 O ANISOU 3053 O HOH A2225 3016 3425 3534 11 97 78 O HETATM 3054 O HOH A2226 -8.749 3.019 12.867 1.00 44.97 O ANISOU 3054 O HOH A2226 5639 5695 5753 5 -21 0 O HETATM 3055 O HOH A2227 -18.823 -2.020 2.986 1.00 57.04 O ANISOU 3055 O HOH A2227 7274 7177 7219 -24 -24 7 O HETATM 3056 O HOH A2228 9.862 7.747 0.961 1.00 43.99 O ANISOU 3056 O HOH A2228 5705 5432 5576 -104 148 -24 O HETATM 3057 O HOH A2229 6.258 4.927 8.256 1.00 32.11 O ANISOU 3057 O HOH A2229 4068 4049 4082 -92 6 -220 O HETATM 3058 O HOH A2230 10.659 6.593 11.741 1.00 53.09 O ANISOU 3058 O HOH A2230 6663 6725 6784 -37 -107 -21 O HETATM 3059 O HOH A2231 13.709 -2.744 6.325 1.00 41.89 O ANISOU 3059 O HOH A2231 5268 5405 5244 -43 -103 56 O HETATM 3060 O HOH A2232 12.919 -2.079 10.781 1.00 67.96 O ANISOU 3060 O HOH A2232 8634 8611 8574 25 21 9 O HETATM 3061 O HOH A2233 6.701 3.511 10.712 1.00 63.13 O ANISOU 3061 O HOH A2233 8016 8036 7933 -12 -26 20 O HETATM 3062 O HOH A2234 6.243 11.495 6.102 1.00 38.70 O ANISOU 3062 O HOH A2234 4739 4884 5079 12 -19 -65 O HETATM 3063 O HOH A2235 6.406 7.332 10.715 1.00 53.63 O ANISOU 3063 O HOH A2235 6793 6809 6773 88 -72 26 O HETATM 3064 O HOH A2236 6.688 11.586 9.634 1.00 40.05 O ANISOU 3064 O HOH A2236 5123 4915 5179 13 -224 -191 O HETATM 3065 O HOH A2237 6.889 9.799 11.423 1.00 51.22 O ANISOU 3065 O HOH A2237 6446 6500 6514 -52 4 0 O HETATM 3066 O HOH A2238 0.460 8.760 4.085 1.00 75.39 O ANISOU 3066 O HOH A2238 9550 9502 9593 22 15 -3 O HETATM 3067 O HOH A2239 3.336 3.366 8.439 1.00 33.65 O ANISOU 3067 O HOH A2239 4342 4531 3911 286 88 -31 O HETATM 3068 O HOH A2240 20.610 -5.138 1.038 1.00 47.32 O ANISOU 3068 O HOH A2240 5869 6039 6069 -36 -8 44 O HETATM 3069 O HOH A2241 21.317 -8.177 3.430 1.00 44.74 O ANISOU 3069 O HOH A2241 5540 5758 5700 -133 -42 28 O HETATM 3070 O HOH A2242 18.053 -8.545 -6.654 1.00 56.93 O ANISOU 3070 O HOH A2242 7187 7196 7244 3 3 -10 O HETATM 3071 O HOH A2243 14.370 -13.714 -6.552 1.00 47.83 O ANISOU 3071 O HOH A2243 6083 6076 6013 47 -5 7 O HETATM 3072 O HOH A2244 2.979 2.593 15.212 1.00 60.22 O ANISOU 3072 O HOH A2244 7680 7616 7581 30 22 2 O HETATM 3073 O HOH A2245 0.650 5.880 16.684 1.00 68.72 O ANISOU 3073 O HOH A2245 8715 8697 8699 -3 -24 12 O HETATM 3074 O HOH A2246 20.579 -1.086 0.999 1.00 40.84 O ANISOU 3074 O HOH A2246 5077 5250 5187 10 -6 -9 O HETATM 3075 O HOH A2247 1.503 1.037 7.822 1.00 31.60 O ANISOU 3075 O HOH A2247 4069 4028 3907 -78 -46 -85 O HETATM 3076 O HOH A2248 0.369 0.225 10.695 1.00 40.63 O ANISOU 3076 O HOH A2248 4942 5108 5386 56 -79 169 O HETATM 3077 O HOH A2249 7.668 -3.553 -9.205 1.00 61.07 O ANISOU 3077 O HOH A2249 7753 7722 7728 12 -1 9 O HETATM 3078 O HOH A2250 17.093 4.110 -2.029 1.00 47.78 O ANISOU 3078 O HOH A2250 5987 5935 6232 -53 -39 0 O HETATM 3079 O HOH A2251 15.107 5.616 -0.533 1.00 46.49 O ANISOU 3079 O HOH A2251 5792 5730 6141 -57 -59 11 O HETATM 3080 O HOH A2252 -1.640 3.809 16.878 1.00 70.86 O ANISOU 3080 O HOH A2252 8983 8973 8965 -4 7 -3 O HETATM 3081 O HOH A2253 -5.334 1.518 16.790 1.00 67.51 O ANISOU 3081 O HOH A2253 8585 8544 8521 3 28 -10 O HETATM 3082 O HOH A2254 -9.941 0.608 12.199 1.00 54.47 O ANISOU 3082 O HOH A2254 6959 6885 6851 10 -10 -28 O HETATM 3083 O HOH A2255 -13.803 -9.061 13.520 1.00 62.27 O ANISOU 3083 O HOH A2255 7904 7896 7857 20 37 20 O HETATM 3084 O HOH A2256 -12.869 -3.111 12.990 1.00 49.35 O ANISOU 3084 O HOH A2256 6368 6284 6098 -7 71 -7 O HETATM 3085 O HOH A2257 -19.606 -5.768 4.672 1.00 39.69 O ANISOU 3085 O HOH A2257 4779 5045 5254 15 -1 71 O HETATM 3086 O HOH A2258 -23.805 -4.637 6.567 1.00 64.87 O ANISOU 3086 O HOH A2258 8148 8256 8243 3 -6 -6 O HETATM 3087 O HOH A2259 -20.393 -3.344 10.386 1.00 60.81 O ANISOU 3087 O HOH A2259 7728 7660 7714 16 16 -18 O HETATM 3088 O HOH A2260 -18.884 -4.790 11.648 1.00 48.51 O ANISOU 3088 O HOH A2260 6208 6135 6086 -49 64 -8 O HETATM 3089 O HOH A2261 -22.229 -2.224 9.286 1.00 56.90 O ANISOU 3089 O HOH A2261 7185 7251 7181 1 34 9 O HETATM 3090 O HOH A2262 -19.981 -10.600 5.312 1.00 45.57 O ANISOU 3090 O HOH A2262 5742 5808 5762 -81 24 12 O HETATM 3091 O HOH A2263 -13.961 -12.404 4.600 1.00 60.38 O ANISOU 3091 O HOH A2263 7646 7630 7664 -32 23 -9 O HETATM 3092 O HOH A2264 -12.501 -5.827 1.433 1.00 43.49 O ANISOU 3092 O HOH A2264 5527 5490 5504 44 -5 -2 O HETATM 3093 O HOH A2265 -17.720 -4.427 3.553 1.00 39.55 O ANISOU 3093 O HOH A2265 4755 5211 5060 -25 -109 -11 O HETATM 3094 O HOH A2266 -2.900 7.906 14.613 1.00 41.77 O ANISOU 3094 O HOH A2266 5217 5350 5302 29 5 38 O HETATM 3095 O HOH A2267 4.408 10.281 13.063 1.00 58.18 O ANISOU 3095 O HOH A2267 7465 7273 7366 1 66 14 O HETATM 3096 O HOH A2268 3.443 6.564 10.344 1.00 46.72 O ANISOU 3096 O HOH A2268 5827 5859 6064 -2 39 -60 O HETATM 3097 O HOH A2269 3.718 11.375 15.391 1.00 60.87 O ANISOU 3097 O HOH A2269 7702 7713 7710 12 30 -27 O HETATM 3098 O HOH A2270 2.736 17.429 12.003 1.00 56.37 O ANISOU 3098 O HOH A2270 7030 7110 7275 -77 -42 -77 O HETATM 3099 O HOH A2271 -2.932 20.159 15.962 1.00 58.61 O ANISOU 3099 O HOH A2271 7407 7385 7476 -41 32 -17 O HETATM 3100 O HOH A2272 -4.309 16.588 15.859 1.00 47.14 O ANISOU 3100 O HOH A2272 6025 5966 5919 -44 -86 -98 O HETATM 3101 O HOH A2273 0.647 19.835 14.395 1.00 44.31 O ANISOU 3101 O HOH A2273 5483 5544 5808 50 -31 -203 O HETATM 3102 O HOH A2274 -1.264 16.474 16.507 1.00 59.05 O ANISOU 3102 O HOH A2274 7415 7548 7471 19 -29 -4 O HETATM 3103 O HOH A2275 0.624 15.429 15.080 1.00 38.52 O ANISOU 3103 O HOH A2275 5147 4909 4580 -39 0 -28 O HETATM 3104 O HOH A2276 -2.099 22.707 5.359 1.00 33.35 O ANISOU 3104 O HOH A2276 4238 4018 4413 71 17 -143 O HETATM 3105 O HOH A2277 1.763 23.530 3.701 1.00 51.02 O ANISOU 3105 O HOH A2277 6507 6444 6435 60 11 14 O HETATM 3106 O HOH A2278 3.992 21.398 1.458 1.00 49.95 O ANISOU 3106 O HOH A2278 6306 6251 6422 -31 -52 -38 O HETATM 3107 O HOH A2279 5.279 16.908 -1.809 1.00 58.52 O ANISOU 3107 O HOH A2279 7413 7396 7425 -5 56 24 O HETATM 3108 O HOH A2280 3.716 19.301 -3.043 1.00 49.03 O ANISOU 3108 O HOH A2280 6322 6119 6188 -62 0 39 O HETATM 3109 O HOH A2281 6.468 18.200 -0.027 1.00 52.96 O ANISOU 3109 O HOH A2281 6775 6685 6661 23 44 -4 O HETATM 3110 O HOH A2282 6.498 15.370 4.007 1.00 34.74 O ANISOU 3110 O HOH A2282 4388 4241 4570 -75 -40 -237 O HETATM 3111 O HOH A2283 4.105 19.252 8.050 1.00 36.84 O ANISOU 3111 O HOH A2283 4306 4702 4988 -121 -130 -296 O HETATM 3112 O HOH A2284 5.942 12.841 3.618 1.00 35.06 O ANISOU 3112 O HOH A2284 4352 4413 4556 -64 -208 -197 O HETATM 3113 O HOH A2285 6.271 15.742 1.130 1.00 35.05 O ANISOU 3113 O HOH A2285 4084 4548 4682 -130 -1 -39 O HETATM 3114 O HOH A2286 7.773 13.752 -1.901 1.00 45.47 O ANISOU 3114 O HOH A2286 5700 5813 5762 -49 -76 -81 O HETATM 3115 O HOH A2287 2.704 8.799 -2.124 1.00 25.44 O ANISOU 3115 O HOH A2287 3242 3189 3234 -82 1 45 O HETATM 3116 O HOH A2288 0.056 2.048 -1.525 1.00 24.25 O ANISOU 3116 O HOH A2288 3009 3041 3162 -16 -77 -42 O HETATM 3117 O HOH A2289 5.379 -0.349 10.589 1.00 47.74 O ANISOU 3117 O HOH A2289 6284 6023 5830 85 76 55 O HETATM 3118 O HOH A2290 9.475 -2.392 7.079 1.00 35.71 O ANISOU 3118 O HOH A2290 4448 4586 4532 -59 -71 -20 O HETATM 3119 O HOH A2291 5.821 -3.035 9.366 1.00 54.24 O ANISOU 3119 O HOH A2291 6826 7002 6780 -16 -45 -24 O HETATM 3120 O HOH A2292 8.172 -9.191 5.420 1.00 37.02 O ANISOU 3120 O HOH A2292 4876 4576 4614 98 83 372 O HETATM 3121 O HOH A2293 8.341 -6.061 13.662 1.00 58.78 O ANISOU 3121 O HOH A2293 7520 7364 7449 -14 -36 7 O HETATM 3122 O HOH A2294 8.563 -7.357 10.924 1.00 73.15 O ANISOU 3122 O HOH A2294 9253 9275 9266 0 2 -16 O HETATM 3123 O HOH A2295 14.757 -6.410 7.385 1.00 63.96 O ANISOU 3123 O HOH A2295 8074 8086 8139 -14 17 -8 O HETATM 3124 O HOH A2296 13.135 -13.870 2.703 1.00 53.97 O ANISOU 3124 O HOH A2296 6840 6825 6838 -12 -9 73 O HETATM 3125 O HOH A2297 13.894 -13.220 0.386 1.00 57.67 O ANISOU 3125 O HOH A2297 7358 7265 7289 12 37 -25 O HETATM 3126 O HOH A2298 14.557 -12.223 4.284 1.00 45.60 O ANISOU 3126 O HOH A2298 5865 5607 5854 8 38 32 O HETATM 3127 O HOH A2299 18.931 -7.124 2.000 1.00 43.31 O ANISOU 3127 O HOH A2299 5321 5513 5619 -4 -25 26 O HETATM 3128 O HOH A2300 16.686 -9.880 -4.771 1.00 41.72 O ANISOU 3128 O HOH A2300 5374 5155 5321 46 -27 -7 O HETATM 3129 O HOH A2301 10.669 -11.028 -1.695 1.00 44.83 O ANISOU 3129 O HOH A2301 5580 5632 5821 -11 2 -18 O HETATM 3130 O HOH A2302 19.608 -3.189 -0.503 1.00 35.63 O ANISOU 3130 O HOH A2302 4386 4407 4742 -71 -35 0 O HETATM 3131 O HOH A2303 22.433 -7.279 -4.467 1.00 56.49 O ANISOU 3131 O HOH A2303 7121 7186 7156 -20 -1 11 O HETATM 3132 O HOH A2304 13.715 -3.187 -9.294 1.00 62.65 O ANISOU 3132 O HOH A2304 7965 7873 7964 5 60 34 O HETATM 3133 O HOH A2305 11.868 -0.133 -7.449 1.00 41.10 O ANISOU 3133 O HOH A2305 5459 5190 4965 -14 119 -53 O HETATM 3134 O HOH A2306 9.467 -4.907 -8.910 1.00 58.11 O ANISOU 3134 O HOH A2306 7371 7363 7342 -13 3 45 O HETATM 3135 O HOH A2307 16.765 2.464 -3.967 1.00 40.03 O ANISOU 3135 O HOH A2307 4982 5047 5178 1 105 -53 O HETATM 3136 O HOH A2308 12.604 4.986 0.897 1.00 38.04 O ANISOU 3136 O HOH A2308 4705 4616 5132 -53 -124 45 O HETATM 3137 O HOH A2309 11.443 -2.684 4.864 1.00 34.28 O ANISOU 3137 O HOH A2309 4598 4275 4152 -91 73 13 O HETATM 3138 O HOH A2310 20.549 -4.733 4.336 1.00 39.17 O ANISOU 3138 O HOH A2310 4791 5131 4960 -43 -96 75 O HETATM 3139 O HOH A2311 19.896 5.367 0.535 1.00 54.23 O ANISOU 3139 O HOH A2311 6850 6899 6854 -4 -43 16 O HETATM 3140 O HOH A2312 16.429 5.430 7.246 1.00 73.11 O ANISOU 3140 O HOH A2312 9225 9255 9297 5 -29 17 O HETATM 3141 O HOH A2313 13.956 6.284 7.226 1.00 40.87 O ANISOU 3141 O HOH A2313 5108 5247 5174 -109 -102 -39 O HETATM 3142 O HOH A2314 18.990 0.955 1.582 1.00 43.03 O ANISOU 3142 O HOH A2314 5279 5577 5492 -59 -102 -20 O HETATM 3143 O HOH A2315 9.716 -1.305 -8.015 1.00 52.60 O ANISOU 3143 O HOH A2315 6628 6665 6690 60 24 0 O HETATM 3144 O HOH A2316 6.267 2.974 -9.523 1.00 36.99 O ANISOU 3144 O HOH A2316 4790 4863 4399 256 11 0 O HETATM 3145 O HOH A2317 13.510 6.381 -2.982 1.00 37.85 O ANISOU 3145 O HOH A2317 4584 4644 5153 -145 -36 87 O HETATM 3146 O HOH A2318 5.708 -1.776 -8.523 1.00 34.05 O ANISOU 3146 O HOH A2318 4602 4319 4013 -65 19 78 O HETATM 3147 O HOH B2001 4.585 -7.921 -9.979 1.00 47.25 O ANISOU 3147 O HOH B2001 6119 5876 5957 6 -12 -29 O HETATM 3148 O HOH B2002 11.872 -6.957 -10.458 1.00 50.95 O ANISOU 3148 O HOH B2002 6432 6458 6466 21 -39 -4 O HETATM 3149 O HOH B2003 9.616 -9.238 -13.543 1.00 59.91 O ANISOU 3149 O HOH B2003 7570 7610 7581 1 0 11 O HETATM 3150 O HOH B2004 10.407 -2.947 -2.798 1.00 69.17 O ANISOU 3150 O HOH B2004 8774 8758 8749 20 24 21 O HETATM 3151 O HOH B2005 8.023 -2.531 -1.376 1.00 69.69 O ANISOU 3151 O HOH B2005 8854 8834 8791 9 16 14 O HETATM 3152 O HOH B2006 3.049 -7.279 -4.579 1.00 31.91 O ANISOU 3152 O HOH B2006 3860 4140 4124 -46 128 66 O HETATM 3153 O HOH B2007 7.779 -10.112 2.117 1.00 42.46 O ANISOU 3153 O HOH B2007 5262 5356 5512 -43 11 -2 O HETATM 3154 O HOH B2008 8.700 -14.450 -2.054 1.00 56.19 O ANISOU 3154 O HOH B2008 7120 7096 7132 2 23 15 O HETATM 3155 O HOH B2009 1.481 -10.388 9.212 1.00 38.33 O ANISOU 3155 O HOH B2009 4850 5000 4713 87 18 47 O HETATM 3156 O HOH B2010 3.219 -9.067 11.137 1.00 74.36 O ANISOU 3156 O HOH B2010 9404 9441 9408 -2 -3 -25 O HETATM 3157 O HOH B2011 1.411 -2.178 12.177 1.00 53.20 O ANISOU 3157 O HOH B2011 6711 6836 6665 38 0 16 O HETATM 3158 O HOH B2012 4.633 -10.959 9.099 1.00 44.11 O ANISOU 3158 O HOH B2012 5616 5462 5679 3 -4 136 O HETATM 3159 O HOH B2013 -3.182 -8.699 18.352 1.00 60.57 O ANISOU 3159 O HOH B2013 7651 7695 7666 12 11 10 O HETATM 3160 O HOH B2014 -0.702 -5.610 18.308 1.00 58.94 O ANISOU 3160 O HOH B2014 7482 7514 7399 -1 -51 -52 O HETATM 3161 O HOH B2015 0.650 -8.869 12.546 1.00 58.82 O ANISOU 3161 O HOH B2015 7470 7366 7511 11 18 10 O HETATM 3162 O HOH B2016 -5.422 -2.954 12.672 1.00 44.55 O ANISOU 3162 O HOH B2016 5871 5640 5414 0 -121 60 O HETATM 3163 O HOH B2017 -7.065 -3.201 14.675 1.00 65.34 O ANISOU 3163 O HOH B2017 8295 8300 8232 -17 18 8 O HETATM 3164 O HOH B2018 -11.794 -7.050 19.376 1.00 69.67 O ANISOU 3164 O HOH B2018 8834 8832 8804 19 -5 2 O HETATM 3165 O HOH B2019 -9.294 -4.282 15.375 1.00 63.83 O ANISOU 3165 O HOH B2019 8129 8070 8052 17 9 -11 O HETATM 3166 O HOH B2020 12.134 -9.464 -11.025 1.00 52.45 O ANISOU 3166 O HOH B2020 6642 6640 6646 0 -4 0 O HETATM 3167 O HOH B2021 2.843 -8.807 -7.071 1.00 33.72 O ANISOU 3167 O HOH B2021 4537 4166 4107 81 -69 -28 O HETATM 3168 O HOH B2022 8.386 -16.452 -3.909 1.00 51.45 O ANISOU 3168 O HOH B2022 6492 6526 6530 -8 42 -8 O HETATM 3169 O HOH B2023 8.208 -14.873 1.056 1.00 63.50 O ANISOU 3169 O HOH B2023 7991 8065 8068 -14 -4 7 O HETATM 3170 O HOH B2024 8.413 -13.309 3.753 1.00 48.90 O ANISOU 3170 O HOH B2024 6267 6227 6083 37 29 24 O HETATM 3171 O HOH B2025 7.107 -11.047 4.169 1.00 42.16 O ANISOU 3171 O HOH B2025 5273 5421 5322 102 17 123 O HETATM 3172 O HOH B2026 0.670 -11.489 6.950 1.00 35.88 O ANISOU 3172 O HOH B2026 4451 4713 4467 -85 -154 223 O HETATM 3173 O HOH B2027 2.329 -1.992 9.142 1.00 46.97 O ANISOU 3173 O HOH B2027 6120 6013 5712 -39 3 -10 O HETATM 3174 O HOH B2028 -4.884 -5.788 12.940 1.00 50.33 O ANISOU 3174 O HOH B2028 6493 6248 6382 15 32 30 O HETATM 3175 O HOH B2029 -10.259 -0.893 15.474 1.00 58.21 O ANISOU 3175 O HOH B2029 7395 7372 7350 9 -9 -9 O HETATM 3176 O HOH E2001 31.404 3.001 16.982 1.00 58.69 O ANISOU 3176 O HOH E2001 7502 7439 7355 -10 -43 2 O HETATM 3177 O HOH E2002 28.865 2.352 14.319 1.00 50.28 O ANISOU 3177 O HOH E2002 6331 6411 6360 72 -28 -47 O HETATM 3178 O HOH E2003 39.202 5.508 25.654 1.00 58.49 O ANISOU 3178 O HOH E2003 7435 7406 7382 -8 18 12 O HETATM 3179 O HOH E2004 35.440 5.578 27.311 1.00 54.66 O ANISOU 3179 O HOH E2004 7037 6914 6816 -11 -2 -2 O HETATM 3180 O HOH E2005 36.945 11.413 17.574 1.00 59.00 O ANISOU 3180 O HOH E2005 7496 7448 7471 -4 11 -12 O HETATM 3181 O HOH E2006 40.389 9.198 23.119 1.00 54.53 O ANISOU 3181 O HOH E2006 6952 6876 6889 -4 1 -21 O HETATM 3182 O HOH E2007 29.138 10.495 18.613 1.00 33.72 O ANISOU 3182 O HOH E2007 4380 4243 4186 -62 93 -16 O HETATM 3183 O HOH E2008 26.890 16.927 23.719 1.00 52.13 O ANISOU 3183 O HOH E2008 6676 6609 6519 23 4 -34 O HETATM 3184 O HOH E2009 25.206 15.387 25.070 1.00 59.11 O ANISOU 3184 O HOH E2009 7515 7502 7442 15 34 0 O HETATM 3185 O HOH E2010 38.800 13.083 22.074 1.00 63.22 O ANISOU 3185 O HOH E2010 8053 7986 7981 4 8 19 O HETATM 3186 O HOH E2011 36.009 16.525 22.708 1.00 61.85 O ANISOU 3186 O HOH E2011 7837 7810 7851 -4 38 0 O HETATM 3187 O HOH E2012 33.751 14.243 25.997 1.00 70.68 O ANISOU 3187 O HOH E2012 8963 8944 8946 -3 17 13 O HETATM 3188 O HOH E2013 36.973 14.108 18.744 1.00 58.55 O ANISOU 3188 O HOH E2013 7436 7460 7350 -45 -50 -15 O HETATM 3189 O HOH E2014 31.475 10.788 14.482 1.00 62.49 O ANISOU 3189 O HOH E2014 7931 7885 7925 30 -6 -43 O HETATM 3190 O HOH E2015 30.470 9.860 16.560 1.00 50.36 O ANISOU 3190 O HOH E2015 6364 6352 6419 44 8 5 O HETATM 3191 O HOH E2016 36.961 7.345 15.940 1.00 62.39 O ANISOU 3191 O HOH E2016 7922 7912 7869 23 -33 2 O HETATM 3192 O HOH E2017 33.143 15.235 15.769 1.00 33.00 O ANISOU 3192 O HOH E2017 4348 4090 4099 47 129 101 O HETATM 3193 O HOH E2018 24.841 14.422 16.894 1.00 54.00 O ANISOU 3193 O HOH E2018 6951 6758 6808 1 40 -3 O HETATM 3194 O HOH E2019 29.393 17.317 30.890 1.00 62.50 O ANISOU 3194 O HOH E2019 7897 7922 7929 -3 9 -1 O HETATM 3195 O HOH E2020 40.026 15.063 18.917 1.00 61.81 O ANISOU 3195 O HOH E2020 7819 7830 7836 13 -3 -24 O HETATM 3196 O HOH E2021 29.300 19.521 13.271 1.00 45.52 O ANISOU 3196 O HOH E2021 5756 5701 5837 80 75 23 O HETATM 3197 O HOH E2022 33.936 17.854 14.977 1.00 60.69 O ANISOU 3197 O HOH E2022 7705 7665 7686 22 7 -1 O HETATM 3198 O HOH E2023 32.959 20.405 11.224 1.00 50.85 O ANISOU 3198 O HOH E2023 6395 6481 6444 -8 -9 22 O HETATM 3199 O HOH E2024 32.281 25.504 13.524 1.00 50.07 O ANISOU 3199 O HOH E2024 6393 6254 6376 27 0 11 O HETATM 3200 O HOH E2025 29.558 23.591 10.570 1.00 56.71 O ANISOU 3200 O HOH E2025 7189 7174 7184 20 -28 -29 O HETATM 3201 O HOH E2026 23.432 30.990 10.370 1.00 50.57 O ANISOU 3201 O HOH E2026 6363 6344 6506 -5 -32 -3 O HETATM 3202 O HOH E2027 30.220 28.547 4.030 1.00 65.92 O ANISOU 3202 O HOH E2027 8405 8315 8324 -1 -6 -10 O HETATM 3203 O HOH E2028 23.832 25.796 13.467 1.00 44.90 O ANISOU 3203 O HOH E2028 5618 5695 5744 40 62 21 O HETATM 3204 O HOH E2029 23.003 22.538 10.071 1.00 40.36 O ANISOU 3204 O HOH E2029 5154 5137 5043 142 -81 -81 O HETATM 3205 O HOH E2030 23.269 27.620 6.910 1.00 55.84 O ANISOU 3205 O HOH E2030 7147 7063 7003 -12 59 11 O HETATM 3206 O HOH E2031 20.724 28.278 6.214 1.00 64.02 O ANISOU 3206 O HOH E2031 8076 8126 8122 2 -19 -8 O HETATM 3207 O HOH E2032 20.825 26.130 3.798 1.00 67.59 O ANISOU 3207 O HOH E2032 8554 8544 8583 -15 0 -1 O HETATM 3208 O HOH E2033 18.904 25.068 5.149 1.00 48.66 O ANISOU 3208 O HOH E2033 5921 6212 6355 -17 8 1 O HETATM 3209 O HOH E2034 19.815 30.539 8.457 1.00 43.35 O ANISOU 3209 O HOH E2034 5359 5541 5568 -11 104 68 O HETATM 3210 O HOH E2035 21.640 27.207 14.347 1.00 33.50 O ANISOU 3210 O HOH E2035 4222 4171 4333 -7 216 -62 O HETATM 3211 O HOH E2036 27.457 23.140 7.336 1.00 67.14 O ANISOU 3211 O HOH E2036 8505 8510 8494 -28 -18 10 O HETATM 3212 O HOH E2037 20.323 23.356 3.022 1.00 47.02 O ANISOU 3212 O HOH E2037 5813 6093 5957 -32 29 0 O HETATM 3213 O HOH E2038 17.200 24.013 2.251 1.00 55.43 O ANISOU 3213 O HOH E2038 6983 7063 7013 -30 15 -13 O HETATM 3214 O HOH E2039 13.307 24.109 -2.521 1.00 61.26 O ANISOU 3214 O HOH E2039 7788 7737 7750 -4 -9 -7 O HETATM 3215 O HOH E2040 14.260 29.514 3.281 1.00 44.23 O ANISOU 3215 O HOH E2040 5592 5428 5786 -91 164 84 O HETATM 3216 O HOH E2041 7.493 24.552 -0.215 1.00 68.11 O ANISOU 3216 O HOH E2041 8628 8621 8630 -5 10 -9 O HETATM 3217 O HOH E2042 -1.641 23.643 7.879 1.00 44.00 O ANISOU 3217 O HOH E2042 5811 5500 5407 -29 34 -20 O HETATM 3218 O HOH E2043 -1.364 24.263 10.024 1.00 49.10 O ANISOU 3218 O HOH E2043 6342 6141 6171 -5 17 7 O HETATM 3219 O HOH E2044 -2.849 25.297 11.529 1.00 46.71 O ANISOU 3219 O HOH E2044 5916 5887 5943 -61 16 17 O HETATM 3220 O HOH E2045 -0.159 24.673 4.442 1.00 38.94 O ANISOU 3220 O HOH E2045 4753 4796 5246 -58 73 -128 O HETATM 3221 O HOH E2046 -4.398 23.598 4.383 1.00 36.47 O ANISOU 3221 O HOH E2046 4521 4491 4844 26 -96 -131 O HETATM 3222 O HOH E2047 -4.394 28.817 13.589 1.00 50.75 O ANISOU 3222 O HOH E2047 6274 6575 6432 -2 15 88 O HETATM 3223 O HOH E2048 0.950 20.538 11.936 1.00 57.84 O ANISOU 3223 O HOH E2048 7329 7279 7367 -55 -12 -11 O HETATM 3224 O HOH E2049 -0.088 21.964 9.454 1.00 51.27 O ANISOU 3224 O HOH E2049 6391 6561 6527 93 -29 29 O HETATM 3225 O HOH E2050 10.619 35.283 6.455 1.00 44.75 O ANISOU 3225 O HOH E2050 5583 5573 5845 -57 73 13 O HETATM 3226 O HOH E2051 11.134 19.806 1.334 1.00 51.40 O ANISOU 3226 O HOH E2051 6333 6634 6559 -12 -55 73 O HETATM 3227 O HOH E2052 18.073 22.003 1.541 1.00 57.51 O ANISOU 3227 O HOH E2052 7312 7250 7287 -9 10 32 O HETATM 3228 O HOH E2053 22.282 19.323 9.581 1.00 52.45 O ANISOU 3228 O HOH E2053 6660 6650 6619 -23 13 50 O HETATM 3229 O HOH E2054 23.057 18.558 5.420 1.00 62.12 O ANISOU 3229 O HOH E2054 7856 7869 7875 24 13 3 O HETATM 3230 O HOH E2055 23.171 15.196 8.262 1.00 64.24 O ANISOU 3230 O HOH E2055 8120 8134 8152 -3 13 -4 O HETATM 3231 O HOH E2056 13.276 7.942 4.362 1.00 60.93 O ANISOU 3231 O HOH E2056 7751 7739 7658 5 0 -13 O HETATM 3232 O HOH E2057 16.504 13.354 2.481 1.00 49.39 O ANISOU 3232 O HOH E2057 6438 6180 6146 31 93 -98 O HETATM 3233 O HOH E2058 19.722 13.176 5.404 1.00 51.31 O ANISOU 3233 O HOH E2058 6545 6570 6377 33 44 2 O HETATM 3234 O HOH E2059 12.565 11.686 4.044 1.00 38.61 O ANISOU 3234 O HOH E2059 4928 4875 4867 207 -28 -120 O HETATM 3235 O HOH E2060 18.835 11.049 8.045 1.00 54.30 O ANISOU 3235 O HOH E2060 6855 6913 6863 42 36 -1 O HETATM 3236 O HOH E2061 11.875 8.464 18.946 1.00 58.21 O ANISOU 3236 O HOH E2061 7390 7320 7406 -23 10 -20 O HETATM 3237 O HOH E2062 14.555 5.798 23.966 1.00 63.85 O ANISOU 3237 O HOH E2062 8088 8085 8085 -1 -3 0 O HETATM 3238 O HOH E2063 14.335 5.178 20.295 1.00 68.47 O ANISOU 3238 O HOH E2063 8697 8674 8644 4 21 5 O HETATM 3239 O HOH E2064 13.972 11.418 22.036 1.00 64.12 O ANISOU 3239 O HOH E2064 8167 8113 8081 -16 -20 -3 O HETATM 3240 O HOH E2065 19.205 8.136 15.014 1.00 35.93 O ANISOU 3240 O HOH E2065 4734 4335 4582 47 40 -67 O HETATM 3241 O HOH E2066 21.408 11.244 15.111 1.00 42.90 O ANISOU 3241 O HOH E2066 5477 5322 5499 155 34 75 O HETATM 3242 O HOH E2067 21.383 16.006 10.128 1.00 41.36 O ANISOU 3242 O HOH E2067 5297 5230 5186 126 44 22 O HETATM 3243 O HOH E2068 23.775 15.985 15.158 1.00 43.57 O ANISOU 3243 O HOH E2068 5356 5633 5562 128 113 21 O HETATM 3244 O HOH E2069 22.269 17.753 11.806 1.00 44.26 O ANISOU 3244 O HOH E2069 5548 5622 5643 -41 53 -51 O HETATM 3245 O HOH E2070 20.588 21.578 10.400 1.00 36.66 O ANISOU 3245 O HOH E2070 4634 4639 4654 3 -16 -179 O HETATM 3246 O HOH E2071 21.936 32.623 20.602 1.00 49.84 O ANISOU 3246 O HOH E2071 6246 6326 6363 24 -42 6 O HETATM 3247 O HOH E2072 25.413 31.050 18.939 1.00 43.28 O ANISOU 3247 O HOH E2072 5368 5523 5550 8 -72 28 O HETATM 3248 O HOH E2073 23.905 28.634 15.803 1.00 43.38 O ANISOU 3248 O HOH E2073 5514 5576 5391 66 112 121 O HETATM 3249 O HOH E2074 20.529 29.909 22.239 1.00 30.83 O ANISOU 3249 O HOH E2074 3865 3862 3985 2 34 50 O HETATM 3250 O HOH E2075 18.373 29.703 14.460 1.00 30.45 O ANISOU 3250 O HOH E2075 3830 3664 4076 -164 -26 11 O HETATM 3251 O HOH E2076 20.330 36.205 15.955 1.00 49.95 O ANISOU 3251 O HOH E2076 6230 6281 6467 -28 14 6 O HETATM 3252 O HOH E2077 25.715 33.493 20.326 1.00 58.62 O ANISOU 3252 O HOH E2077 7501 7398 7371 31 -14 38 O HETATM 3253 O HOH E2078 23.301 35.107 20.703 1.00 51.30 O ANISOU 3253 O HOH E2078 6502 6507 6480 0 27 -47 O HETATM 3254 O HOH E2079 21.121 41.530 24.832 1.00 60.88 O ANISOU 3254 O HOH E2079 7712 7709 7709 -11 22 -5 O HETATM 3255 O HOH E2080 24.917 37.825 26.235 1.00 55.60 O ANISOU 3255 O HOH E2080 7134 6992 6998 -37 41 34 O HETATM 3256 O HOH E2081 22.908 39.524 24.792 1.00 58.75 O ANISOU 3256 O HOH E2081 7416 7432 7473 -42 32 45 O HETATM 3257 O HOH E2082 23.192 35.930 22.949 1.00 59.09 O ANISOU 3257 O HOH E2082 7448 7539 7462 32 -3 5 O HETATM 3258 O HOH E2083 22.520 40.199 37.274 1.00 65.91 O ANISOU 3258 O HOH E2083 8395 8318 8329 -15 9 9 O HETATM 3259 O HOH E2084 19.984 41.135 30.690 1.00 37.84 O ANISOU 3259 O HOH E2084 4655 4662 5060 -104 -78 29 O HETATM 3260 O HOH E2085 17.804 40.104 35.928 1.00 57.64 O ANISOU 3260 O HOH E2085 7280 7293 7327 -4 -22 -46 O HETATM 3261 O HOH E2086 18.489 41.884 33.177 1.00 47.10 O ANISOU 3261 O HOH E2086 5954 5992 5948 12 16 -1 O HETATM 3262 O HOH E2087 11.312 44.053 34.910 1.00 45.55 O ANISOU 3262 O HOH E2087 5852 5737 5718 21 -27 -62 O HETATM 3263 O HOH E2088 16.941 46.116 27.315 1.00 59.22 O ANISOU 3263 O HOH E2088 7516 7524 7461 0 -2 -24 O HETATM 3264 O HOH E2089 19.594 46.120 31.198 1.00 54.00 O ANISOU 3264 O HOH E2089 6825 6834 6858 -27 7 23 O HETATM 3265 O HOH E2090 11.971 40.075 37.755 1.00 43.70 O ANISOU 3265 O HOH E2090 5501 5501 5600 3 15 28 O HETATM 3266 O HOH E2091 39.358 5.638 30.093 1.00 65.31 O ANISOU 3266 O HOH E2091 8294 8278 8242 8 -7 7 O HETATM 3267 O HOH E2092 9.120 48.160 29.618 1.00 53.17 O ANISOU 3267 O HOH E2092 6729 6731 6740 35 -35 6 O HETATM 3268 O HOH E2093 12.499 49.869 34.029 1.00 60.94 O ANISOU 3268 O HOH E2093 7708 7689 7755 18 5 -8 O HETATM 3269 O HOH E2094 31.725 14.266 27.506 1.00 57.66 O ANISOU 3269 O HOH E2094 7307 7282 7319 -6 10 -6 O HETATM 3270 O HOH E2095 37.782 4.976 17.741 1.00 53.87 O ANISOU 3270 O HOH E2095 6842 6803 6824 -9 51 10 O HETATM 3271 O HOH E2096 29.609 13.755 34.118 1.00 64.11 O ANISOU 3271 O HOH E2096 8114 8110 8132 17 33 7 O HETATM 3272 O HOH E2097 5.097 40.372 24.664 1.00 43.08 O ANISOU 3272 O HOH E2097 5374 5294 5697 21 -70 -8 O HETATM 3273 O HOH E2098 6.385 39.512 30.912 1.00 60.81 O ANISOU 3273 O HOH E2098 7708 7656 7739 -31 9 2 O HETATM 3274 O HOH E2099 4.459 37.964 25.760 1.00 41.73 O ANISOU 3274 O HOH E2099 5415 5077 5361 22 -83 -78 O HETATM 3275 O HOH E2100 27.375 17.899 11.588 1.00 52.07 O ANISOU 3275 O HOH E2100 6649 6584 6551 -15 75 -2 O HETATM 3276 O HOH E2101 30.077 21.062 11.371 1.00 60.18 O ANISOU 3276 O HOH E2101 7591 7611 7662 -4 -1 50 O HETATM 3277 O HOH E2102 13.978 45.337 23.040 1.00 49.91 O ANISOU 3277 O HOH E2102 6325 6256 6381 -9 -12 -6 O HETATM 3278 O HOH E2103 -0.223 44.985 26.137 1.00 68.17 O ANISOU 3278 O HOH E2103 8638 8613 8648 -3 11 -1 O HETATM 3279 O HOH E2104 -0.812 48.939 20.303 1.00 66.12 O ANISOU 3279 O HOH E2104 8409 8376 8336 -6 17 21 O HETATM 3280 O HOH E2105 5.822 48.892 28.699 1.00 52.45 O ANISOU 3280 O HOH E2105 6644 6629 6653 0 5 15 O HETATM 3281 O HOH E2106 1.089 52.061 25.532 1.00 67.68 O ANISOU 3281 O HOH E2106 8562 8575 8578 0 -7 6 O HETATM 3282 O HOH E2107 15.551 25.268 -0.512 1.00 59.11 O ANISOU 3282 O HOH E2107 7445 7511 7500 1 45 29 O HETATM 3283 O HOH E2108 16.852 30.676 4.598 1.00 63.74 O ANISOU 3283 O HOH E2108 8113 8055 8050 23 19 -2 O HETATM 3284 O HOH E2109 7.690 45.468 14.584 1.00 68.38 O ANISOU 3284 O HOH E2109 8661 8698 8619 -1 3 15 O HETATM 3285 O HOH E2110 3.359 51.273 18.642 1.00 57.15 O ANISOU 3285 O HOH E2110 7248 7246 7221 0 3 14 O HETATM 3286 O HOH E2111 -0.313 25.547 1.491 1.00 37.49 O ANISOU 3286 O HOH E2111 4867 4749 4626 24 -21 76 O HETATM 3287 O HOH E2112 -4.373 31.058 15.171 1.00 52.74 O ANISOU 3287 O HOH E2112 6684 6768 6584 10 -31 60 O HETATM 3288 O HOH E2113 2.867 39.817 15.484 1.00 48.00 O ANISOU 3288 O HOH E2113 6193 6070 5974 32 -88 -50 O HETATM 3289 O HOH E2114 3.499 48.390 10.741 1.00 48.77 O ANISOU 3289 O HOH E2114 6259 6251 6021 67 48 63 O HETATM 3290 O HOH E2115 10.399 16.564 0.084 1.00 52.85 O ANISOU 3290 O HOH E2115 6687 6769 6624 -34 -20 37 O HETATM 3291 O HOH E2116 9.997 46.888 19.096 1.00 56.93 O ANISOU 3291 O HOH E2116 7240 7183 7208 -15 -5 33 O HETATM 3292 O HOH E2117 8.880 38.974 21.316 1.00 31.38 O ANISOU 3292 O HOH E2117 3771 3938 4211 13 -104 69 O HETATM 3293 O HOH E2118 10.147 10.830 3.183 1.00 46.51 O ANISOU 3293 O HOH E2118 5726 5983 5963 43 -124 -130 O HETATM 3294 O HOH E2119 14.157 11.812 1.870 1.00 49.60 O ANISOU 3294 O HOH E2119 6344 6317 6182 83 29 -24 O HETATM 3295 O HOH E2120 18.759 11.054 3.346 1.00 61.31 O ANISOU 3295 O HOH E2120 7742 7736 7816 -7 4 23 O HETATM 3296 O HOH E2121 14.415 8.784 1.413 1.00 61.25 O ANISOU 3296 O HOH E2121 7807 7712 7749 -8 -14 -41 O HETATM 3297 O HOH E2122 7.816 33.226 22.362 1.00 36.33 O ANISOU 3297 O HOH E2122 4596 4629 4577 40 29 39 O HETATM 3298 O HOH E2123 4.137 36.086 17.359 1.00 37.28 O ANISOU 3298 O HOH E2123 4806 4646 4712 -127 -140 30 O HETATM 3299 O HOH E2124 4.942 36.120 14.614 1.00 42.19 O ANISOU 3299 O HOH E2124 5406 5275 5347 -53 28 15 O HETATM 3300 O HOH E2125 18.823 6.107 16.729 1.00 49.71 O ANISOU 3300 O HOH E2125 6369 6274 6245 -30 10 -40 O HETATM 3301 O HOH E2126 15.686 11.433 24.980 1.00 57.41 O ANISOU 3301 O HOH E2126 7313 7231 7269 -5 -6 14 O HETATM 3302 O HOH E2127 11.499 4.619 18.454 1.00 66.76 O ANISOU 3302 O HOH E2127 8448 8474 8443 3 -9 -14 O HETATM 3303 O HOH E2128 15.123 3.418 22.287 1.00 58.23 O ANISOU 3303 O HOH E2128 7379 7384 7361 5 4 -1 O HETATM 3304 O HOH E2129 24.888 16.606 12.635 1.00 41.25 O ANISOU 3304 O HOH E2129 5570 5019 5084 34 39 -48 O HETATM 3305 O HOH E2130 9.983 24.605 25.419 1.00 27.95 O ANISOU 3305 O HOH E2130 3446 3661 3513 -129 -101 -77 O HETATM 3306 O HOH E2131 21.337 32.390 23.158 1.00 51.21 O ANISOU 3306 O HOH E2131 6482 6424 6550 -28 24 -53 O HETATM 3307 O HOH E2132 24.860 34.788 24.358 1.00 53.29 O ANISOU 3307 O HOH E2132 6716 6806 6723 8 48 48 O HETATM 3308 O HOH E2133 11.733 29.363 33.209 1.00 36.82 O ANISOU 3308 O HOH E2133 4575 4872 4539 -142 -280 -175 O HETATM 3309 O HOH E2134 13.361 23.915 34.990 1.00 65.58 O ANISOU 3309 O HOH E2134 8324 8252 8342 1 1 -2 O HETATM 3310 O HOH E2135 14.854 25.569 32.272 1.00 42.18 O ANISOU 3310 O HOH E2135 5440 5383 5203 -51 -94 -99 O HETATM 3311 O HOH E2136 13.793 25.437 39.053 1.00 38.69 O ANISOU 3311 O HOH E2136 4862 4943 4892 93 65 -44 O HETATM 3312 O HOH E2137 9.776 26.277 34.864 1.00 41.60 O ANISOU 3312 O HOH E2137 5218 5299 5286 116 20 2 O HETATM 3313 O HOH E2138 11.473 46.965 35.250 1.00 62.97 O ANISOU 3313 O HOH E2138 7970 7929 8027 -6 -9 -7 O HETATM 3314 O HOH E2139 21.106 44.534 32.866 1.00 64.08 O ANISOU 3314 O HOH E2139 8133 8096 8115 9 -19 -10 O HETATM 3315 O HOH E2140 10.034 48.903 33.506 1.00 49.92 O ANISOU 3315 O HOH E2140 6319 6362 6286 -12 -19 0 O HETATM 3316 O HOH E2141 30.672 10.839 27.980 1.00 60.65 O ANISOU 3316 O HOH E2141 7755 7686 7602 32 11 15 O HETATM 3317 O HOH E2142 20.976 29.904 44.326 1.00 50.15 O ANISOU 3317 O HOH E2142 6316 6443 6293 17 -21 45 O HETATM 3318 O HOH E2143 23.093 26.262 40.497 1.00 64.64 O ANISOU 3318 O HOH E2143 8221 8163 8173 11 20 9 O HETATM 3319 O HOH E2144 19.182 25.994 37.371 1.00 43.52 O ANISOU 3319 O HOH E2144 5370 5458 5706 -16 -29 96 O HETATM 3320 O HOH E2145 17.803 27.393 41.511 1.00 48.57 O ANISOU 3320 O HOH E2145 6165 6172 6115 -61 143 -45 O HETATM 3321 O HOH E2146 12.593 47.029 19.478 1.00 57.27 O ANISOU 3321 O HOH E2146 7266 7203 7288 -4 37 43 O HETATM 3322 O HOH E2147 -3.843 49.505 20.335 1.00 55.83 O ANISOU 3322 O HOH E2147 7114 7072 7024 0 18 -8 O HETATM 3323 O HOH E2148 -2.018 42.734 29.048 1.00 69.44 O ANISOU 3323 O HOH E2148 8802 8800 8780 -5 -10 11 O HETATM 3324 O HOH E2149 11.502 32.204 35.991 1.00 31.10 O ANISOU 3324 O HOH E2149 3897 3938 3980 11 207 -79 O HETATM 3325 O HOH E2150 18.110 36.312 35.983 1.00 34.52 O ANISOU 3325 O HOH E2150 4410 4208 4497 -91 23 -102 O HETATM 3326 O HOH E2151 1.807 37.719 17.973 1.00 56.90 O ANISOU 3326 O HOH E2151 7222 7195 7203 -6 39 22 O HETATM 3327 O HOH E2152 12.386 14.874 -1.015 1.00 53.75 O ANISOU 3327 O HOH E2152 6905 6874 6643 64 30 -26 O HETATM 3328 O HOH E2153 24.188 35.926 34.957 1.00 56.84 O ANISOU 3328 O HOH E2153 7198 7197 7200 -20 -17 0 O HETATM 3329 O HOH E2154 12.135 12.650 -0.103 1.00 57.89 O ANISOU 3329 O HOH E2154 7427 7329 7237 22 42 -58 O HETATM 3330 O HOH E2155 19.705 9.555 1.537 1.00 58.86 O ANISOU 3330 O HOH E2155 7399 7454 7510 -13 -6 0 O HETATM 3331 O HOH E2156 15.908 9.188 26.446 1.00 54.89 O ANISOU 3331 O HOH E2156 6990 6956 6909 37 -3 15 O HETATM 3332 O HOH E2157 15.169 10.847 28.099 1.00 53.25 O ANISOU 3332 O HOH E2157 6806 6703 6723 -2 0 -7 O HETATM 3333 O HOH E2158 10.410 2.204 16.645 1.00 60.31 O ANISOU 3333 O HOH E2158 7673 7598 7644 7 -5 -16 O HETATM 3334 O HOH E2159 8.893 3.576 18.657 1.00 59.36 O ANISOU 3334 O HOH E2159 7534 7529 7490 4 1 2 O HETATM 3335 O HOH E2160 16.211 40.076 19.219 1.00 40.26 O ANISOU 3335 O HOH E2160 5112 5084 5099 -78 -135 140 O HETATM 3336 O HOH E2161 10.349 31.092 33.317 1.00 26.59 O ANISOU 3336 O HOH E2161 3229 3601 3272 -22 -77 62 O HETATM 3337 O HOH E2162 -2.413 45.311 32.571 1.00 58.56 O ANISOU 3337 O HOH E2162 7467 7377 7404 23 1 0 O HETATM 3338 O HOH E2163 9.186 40.770 15.524 1.00 44.96 O ANISOU 3338 O HOH E2163 5691 5520 5871 -42 0 -23 O HETATM 3339 O HOH E2164 11.570 43.659 15.060 1.00 60.06 O ANISOU 3339 O HOH E2164 7619 7618 7581 39 6 26 O HETATM 3340 O HOH E2165 19.026 45.119 12.854 1.00 71.06 O ANISOU 3340 O HOH E2165 9008 9002 8990 -1 -2 9 O HETATM 3341 O HOH E2166 16.504 37.616 16.738 1.00 35.40 O ANISOU 3341 O HOH E2166 4357 4592 4498 -62 66 218 O HETATM 3342 O HOH E2167 18.425 39.375 18.281 1.00 57.96 O ANISOU 3342 O HOH E2167 7306 7380 7336 19 -84 1 O HETATM 3343 O HOH E2168 16.836 41.942 9.614 1.00 63.79 O ANISOU 3343 O HOH E2168 8041 8081 8114 16 3 12 O HETATM 3344 O HOH E2169 13.663 37.751 8.815 1.00 41.02 O ANISOU 3344 O HOH E2169 5064 5230 5293 52 -63 -16 O HETATM 3345 O HOH E2170 13.780 34.968 7.806 1.00 50.51 O ANISOU 3345 O HOH E2170 6453 6366 6373 -45 38 -15 O HETATM 3346 O HOH E2171 17.898 35.605 15.610 1.00 40.31 O ANISOU 3346 O HOH E2171 5026 5253 5036 4 -87 70 O HETATM 3347 O HOH E2172 17.167 32.704 6.299 1.00 44.55 O ANISOU 3347 O HOH E2172 5799 5694 5432 -60 -21 43 O HETATM 3348 O HOH E2173 17.414 36.839 6.380 1.00 53.35 O ANISOU 3348 O HOH E2173 6748 6862 6658 -3 14 9 O HETATM 3349 O HOH E2174 22.491 36.138 12.419 1.00 51.01 O ANISOU 3349 O HOH E2174 6372 6494 6513 -24 -12 0 O HETATM 3350 O HOH E2175 5.159 7.944 22.621 1.00 66.93 O ANISOU 3350 O HOH E2175 8478 8496 8454 0 14 9 O HETATM 3351 O HOH E2176 10.369 3.419 14.052 1.00 64.92 O ANISOU 3351 O HOH E2176 8254 8206 8206 22 28 -22 O HETATM 3352 O HOH E2177 14.278 34.511 10.878 1.00 33.85 O ANISOU 3352 O HOH E2177 4035 4246 4578 -137 86 88 O HETATM 3353 O HOH E2178 -0.114 21.154 29.873 1.00 54.58 O ANISOU 3353 O HOH E2178 7027 6893 6815 -7 -11 -18 O HETATM 3354 O HOH E2179 2.188 13.030 21.472 1.00 69.31 O ANISOU 3354 O HOH E2179 8791 8795 8748 -6 -1 18 O HETATM 3355 O HOH E2180 12.834 9.728 25.470 1.00 59.52 O ANISOU 3355 O HOH E2180 7566 7556 7493 6 44 0 O HETATM 3356 O HOH E2181 -2.309 39.022 31.427 1.00 70.17 O ANISOU 3356 O HOH E2181 8886 8860 8913 -1 -6 0 O HETATM 3357 O HOH E2182 16.702 31.623 15.713 1.00 31.18 O ANISOU 3357 O HOH E2182 3603 4036 4207 -139 -34 15 O HETATM 3358 O HOH E2183 0.971 22.501 15.149 1.00 40.91 O ANISOU 3358 O HOH E2183 5134 5199 5208 31 -98 -152 O HETATM 3359 O HOH E2184 7.038 10.015 21.854 1.00 74.29 O ANISOU 3359 O HOH E2184 9427 9405 9394 -13 4 12 O HETATM 3360 O HOH E2185 13.293 4.787 14.282 1.00 63.68 O ANISOU 3360 O HOH E2185 8062 8046 8085 6 -35 3 O HETATM 3361 O HOH E2186 13.074 3.443 11.050 1.00 60.32 O ANISOU 3361 O HOH E2186 7736 7631 7550 19 -39 3 O HETATM 3362 O HOH E2187 2.085 17.794 15.244 1.00 45.17 O ANISOU 3362 O HOH E2187 5713 5596 5850 -12 -76 60 O HETATM 3363 O HOH E2188 6.198 18.462 20.937 1.00 35.67 O ANISOU 3363 O HOH E2188 4565 4375 4613 -81 -4 -23 O HETATM 3364 O HOH E2189 4.878 14.563 22.561 1.00 71.50 O ANISOU 3364 O HOH E2189 9051 9068 9047 26 -17 11 O HETATM 3365 O HOH E2190 1.870 15.057 23.215 1.00 62.53 O ANISOU 3365 O HOH E2190 7967 7876 7915 -26 -18 9 O HETATM 3366 O HOH E2191 -0.849 23.168 27.729 1.00 44.42 O ANISOU 3366 O HOH E2191 5426 5576 5872 11 -22 30 O HETATM 3367 O HOH E2192 2.288 13.378 16.094 1.00 53.12 O ANISOU 3367 O HOH E2192 6742 6781 6657 73 -40 -26 O HETATM 3368 O HOH E2193 4.450 14.576 15.165 1.00 45.69 O ANISOU 3368 O HOH E2193 5778 5757 5822 -62 -16 -161 O HETATM 3369 O HOH E2194 6.421 12.997 17.022 1.00 54.43 O ANISOU 3369 O HOH E2194 6946 6875 6857 -22 -35 -104 O HETATM 3370 O HOH E2195 8.967 19.386 21.923 1.00 33.29 O ANISOU 3370 O HOH E2195 4109 4234 4304 248 121 166 O HETATM 3371 O HOH E2196 11.121 12.944 25.320 1.00 68.13 O ANISOU 3371 O HOH E2196 8626 8628 8630 -15 0 -1 O HETATM 3372 O HOH E2197 -1.635 38.637 28.259 1.00 58.65 O ANISOU 3372 O HOH E2197 7396 7468 7418 -13 16 -14 O HETATM 3373 O HOH E2198 -9.670 35.655 21.618 1.00 64.37 O ANISOU 3373 O HOH E2198 8121 8160 8176 -14 -13 4 O HETATM 3374 O HOH E2199 12.385 20.255 25.499 1.00 34.97 O ANISOU 3374 O HOH E2199 4479 4369 4439 -50 42 99 O HETATM 3375 O HOH E2200 10.684 21.512 23.382 1.00 31.38 O ANISOU 3375 O HOH E2200 3887 3983 4050 -232 39 -31 O HETATM 3376 O HOH E2201 16.933 13.816 24.755 1.00 67.12 O ANISOU 3376 O HOH E2201 8536 8513 8452 5 10 13 O HETATM 3377 O HOH E2202 23.159 19.173 27.359 1.00 68.13 O ANISOU 3377 O HOH E2202 8672 8612 8602 5 7 -3 O HETATM 3378 O HOH E2203 20.694 19.078 27.764 1.00 65.49 O ANISOU 3378 O HOH E2203 8280 8269 8334 3 -15 -23 O HETATM 3379 O HOH E2204 17.976 20.670 28.542 1.00 35.57 O ANISOU 3379 O HOH E2204 4539 4430 4544 -21 -4 81 O HETATM 3380 O HOH E2205 25.757 22.870 32.113 1.00 58.66 O ANISOU 3380 O HOH E2205 7406 7408 7473 5 29 -4 O HETATM 3381 O HOH E2206 24.484 21.380 29.217 1.00 50.09 O ANISOU 3381 O HOH E2206 6442 6331 6258 -4 27 2 O HETATM 3382 O HOH E2207 29.383 21.593 25.328 1.00 49.96 O ANISOU 3382 O HOH E2207 6344 6275 6362 69 20 -7 O HETATM 3383 O HOH E2208 25.786 20.785 27.501 1.00 50.88 O ANISOU 3383 O HOH E2208 6401 6402 6528 17 3 -17 O HETATM 3384 O HOH E2209 31.396 29.985 25.129 1.00 51.59 O ANISOU 3384 O HOH E2209 6568 6541 6489 -40 53 4 O HETATM 3385 O HOH E2210 32.141 23.710 26.545 1.00 54.16 O ANISOU 3385 O HOH E2210 6892 6897 6787 17 62 7 O HETATM 3386 O HOH E2211 23.959 31.712 24.114 1.00 49.53 O ANISOU 3386 O HOH E2211 6146 6385 6285 34 2 20 O HETATM 3387 O HOH E2212 29.290 30.192 23.183 1.00 47.14 O ANISOU 3387 O HOH E2212 5855 5945 6108 -45 18 -9 O HETATM 3388 O HOH E2213 16.220 12.792 20.540 1.00 42.33 O ANISOU 3388 O HOH E2213 5549 5392 5140 -64 -22 50 O HETATM 3389 O HOH E2214 11.305 11.490 22.035 1.00 58.74 O ANISOU 3389 O HOH E2214 7507 7406 7406 6 -16 28 O HETATM 3390 O HOH E2215 8.646 12.804 18.974 1.00 60.20 O ANISOU 3390 O HOH E2215 7569 7616 7686 -11 25 40 O HETATM 3391 O HOH E2216 9.308 9.803 19.573 1.00 67.78 O ANISOU 3391 O HOH E2216 8589 8568 8596 -5 3 -4 O HETATM 3392 O HOH E2217 9.056 16.170 20.110 1.00 52.92 O ANISOU 3392 O HOH E2217 6539 6702 6864 26 83 61 O HETATM 3393 O HOH E2218 5.401 16.956 14.129 1.00 51.60 O ANISOU 3393 O HOH E2218 6655 6583 6366 9 -16 32 O HETATM 3394 O HOH E2219 12.836 6.132 9.809 1.00 47.21 O ANISOU 3394 O HOH E2219 6136 5936 5866 28 -49 -45 O HETATM 3395 O HOH E2220 12.518 7.790 14.678 1.00 41.98 O ANISOU 3395 O HOH E2220 5469 5050 5430 43 1 66 O HETATM 3396 O HOH E2221 9.587 9.197 12.468 1.00 46.23 O ANISOU 3396 O HOH E2221 5904 5605 6053 -125 -99 -168 O HETATM 3397 O HOH E2222 8.487 14.760 0.216 1.00 45.17 O ANISOU 3397 O HOH E2222 5704 5746 5710 8 -105 38 O HETATM 3398 O HOH E2223 8.704 12.875 2.644 1.00 37.69 O ANISOU 3398 O HOH E2223 4702 4743 4874 -139 -84 -109 O HETATM 3399 O HOH E2224 4.932 20.581 5.466 1.00 38.72 O ANISOU 3399 O HOH E2224 4932 4987 4793 62 23 11 O HETATM 3400 O HOH E2225 6.166 19.703 2.001 1.00 39.50 O ANISOU 3400 O HOH E2225 4884 5176 4948 -24 -9 42 O HETATM 3401 O HOH E2226 5.371 17.734 11.144 1.00 34.09 O ANISOU 3401 O HOH E2226 4062 4069 4821 -96 -14 -137 O HETATM 3402 O HOH E2227 2.492 20.983 9.460 1.00 44.44 O ANISOU 3402 O HOH E2227 5535 5662 5685 -34 -25 -242 O HETATM 3403 O HOH E2228 7.625 25.253 11.728 1.00 27.93 O ANISOU 3403 O HOH E2228 3479 3614 3515 -134 97 10 O HETATM 3404 O HOH E2229 10.535 28.896 17.329 1.00 26.80 O ANISOU 3404 O HOH E2229 3436 3364 3382 -203 -52 -40 O HETATM 3405 O HOH E2230 3.148 23.043 26.684 1.00 37.55 O ANISOU 3405 O HOH E2230 4967 4620 4681 -17 78 122 O HETATM 3406 O HOH E2231 4.429 18.468 25.122 1.00 67.06 O ANISOU 3406 O HOH E2231 8553 8466 8461 -2 -3 11 O HETATM 3407 O HOH E2232 4.128 28.960 31.397 1.00 33.41 O ANISOU 3407 O HOH E2232 4181 4734 3777 234 75 184 O HETATM 3408 O HOH E2233 0.992 34.104 30.559 1.00 49.05 O ANISOU 3408 O HOH E2233 6195 6193 6248 32 -25 -36 O HETATM 3409 O HOH E2234 -2.299 24.931 30.362 1.00 63.38 O ANISOU 3409 O HOH E2234 7954 8068 8057 3 -2 16 O HETATM 3410 O HOH E2235 -1.911 26.515 33.683 1.00 37.56 O ANISOU 3410 O HOH E2235 4819 4693 4759 -17 -71 -13 O HETATM 3411 O HOH E2236 -1.749 33.029 33.449 1.00 47.75 O ANISOU 3411 O HOH E2236 6165 5994 5981 59 7 -28 O HETATM 3412 O HOH E2237 0.482 35.755 28.297 1.00 49.82 O ANISOU 3412 O HOH E2237 6325 6276 6327 -33 -8 -116 O HETATM 3413 O HOH E2238 -9.908 31.740 21.784 1.00 61.65 O ANISOU 3413 O HOH E2238 7803 7785 7833 4 -26 -11 O HETATM 3414 O HOH E2239 -8.524 33.464 21.358 1.00 47.81 O ANISOU 3414 O HOH E2239 6010 6045 6110 -46 -45 0 O HETATM 3415 O HOH E2240 -7.279 25.239 23.254 1.00 56.39 O ANISOU 3415 O HOH E2240 7028 7186 7211 5 32 6 O HETATM 3416 O HOH E2241 -2.127 33.191 17.646 1.00 41.16 O ANISOU 3416 O HOH E2241 5207 5107 5324 20 -41 10 O HETATM 3417 O HOH E2242 0.941 24.656 26.044 1.00 37.69 O ANISOU 3417 O HOH E2242 4989 4633 4698 -63 -127 -115 O HETATM 3418 O HOH E2243 -6.115 22.390 15.184 1.00 55.55 O ANISOU 3418 O HOH E2243 7044 7033 7027 1 42 16 O HETATM 3419 O HOH E2244 -5.312 21.252 20.716 1.00 70.96 O ANISOU 3419 O HOH E2244 9014 8990 8954 9 4 -17 O HETATM 3420 O HOH E2245 -1.341 23.468 15.388 1.00 45.59 O ANISOU 3420 O HOH E2245 5743 5767 5810 -70 -48 -47 O HETATM 3421 O HOH E2246 -2.792 25.896 14.464 1.00 46.66 O ANISOU 3421 O HOH E2246 5782 5963 5984 -142 -28 -28 O HETATM 3422 O HOH E2247 2.743 34.011 13.137 1.00 43.16 O ANISOU 3422 O HOH E2247 5501 5411 5484 150 147 64 O HETATM 3423 O HOH E2248 0.644 35.543 17.003 1.00 57.59 O ANISOU 3423 O HOH E2248 7327 7361 7191 68 13 21 O HETATM 3424 O HOH F2001 -2.818 39.059 22.520 1.00 59.00 O ANISOU 3424 O HOH F2001 7515 7477 7424 10 -6 5 O HETATM 3425 O HOH F2002 -1.585 39.610 20.788 1.00 56.20 O ANISOU 3425 O HOH F2002 7079 7140 7131 -26 27 -17 O HETATM 3426 O HOH F2003 7.392 36.266 23.668 1.00 31.61 O ANISOU 3426 O HOH F2003 3867 4047 4094 18 -5 221 O HETATM 3427 O HOH F2004 2.374 37.983 27.546 1.00 67.98 O ANISOU 3427 O HOH F2004 8594 8605 8630 22 14 11 O HETATM 3428 O HOH F2005 4.909 31.089 32.074 1.00 26.33 O ANISOU 3428 O HOH F2005 3294 3498 3209 199 -7 122 O HETATM 3429 O HOH F2006 12.855 26.709 32.349 1.00 44.01 O ANISOU 3429 O HOH F2006 5772 5547 5404 -47 50 -24 O HETATM 3430 O HOH F2007 10.816 24.213 33.506 1.00 43.30 O ANISOU 3430 O HOH F2007 5584 5455 5410 79 21 65 O HETATM 3431 O HOH F2008 11.511 18.238 27.250 1.00 40.14 O ANISOU 3431 O HOH F2008 5217 5015 5019 -7 153 -34 O HETATM 3432 O HOH F2009 10.624 22.232 26.695 1.00 35.14 O ANISOU 3432 O HOH F2009 4573 4274 4504 66 -131 -91 O HETATM 3433 O HOH F2010 7.398 27.081 34.398 1.00 38.20 O ANISOU 3433 O HOH F2010 4914 4760 4840 11 -112 -212 O HETATM 3434 O HOH F2011 6.027 21.788 34.591 1.00 56.24 O ANISOU 3434 O HOH F2011 7093 7118 7156 30 -8 50 O HETATM 3435 O HOH F2012 8.284 22.160 33.935 1.00 50.00 O ANISOU 3435 O HOH F2012 6379 6347 6269 79 11 19 O HETATM 3436 O HOH F2013 14.102 16.322 34.114 1.00 54.07 O ANISOU 3436 O HOH F2013 6906 6812 6826 0 58 -24 O HETATM 3437 O HOH F2014 19.399 24.626 34.391 1.00 62.66 O ANISOU 3437 O HOH F2014 7938 7921 7948 -4 -15 8 O HETATM 3438 O HOH F2015 17.023 23.606 35.813 1.00 67.89 O ANISOU 3438 O HOH F2015 8634 8540 8621 12 13 -1 O HETATM 3439 O HOH F2016 21.764 19.705 40.463 1.00 53.97 O ANISOU 3439 O HOH F2016 6790 6877 6838 -39 32 10 O HETATM 3440 O HOH F2017 7.242 39.134 23.642 1.00 35.44 O ANISOU 3440 O HOH F2017 4503 4474 4486 -33 94 112 O HETATM 3441 O HOH F2018 7.595 29.749 33.575 1.00 36.55 O ANISOU 3441 O HOH F2018 4902 4594 4391 94 101 -104 O CONECT 1315 1324 CONECT 1324 1315 1325 CONECT 1325 1324 1326 1332 CONECT 1326 1325 1327 CONECT 1327 1326 1328 CONECT 1328 1327 1329 CONECT 1329 1328 1330 CONECT 1330 1329 1331 CONECT 1331 1330 CONECT 1332 1325 1333 1334 CONECT 1333 1332 CONECT 1334 1332 CONECT 2704 2713 CONECT 2713 2704 2714 CONECT 2714 2713 2715 2721 CONECT 2715 2714 2716 CONECT 2716 2715 2717 CONECT 2717 2716 2718 CONECT 2718 2717 2719 CONECT 2719 2718 2720 CONECT 2720 2719 CONECT 2721 2714 2722 2723 CONECT 2722 2721 CONECT 2723 2721 CONECT 2779 2780 CONECT 2780 2779 2781 2784 CONECT 2781 2780 2782 CONECT 2782 2781 2783 CONECT 2783 2782 2786 CONECT 2784 2780 2785 CONECT 2785 2784 CONECT 2786 2783 2787 CONECT 2787 2786 2788 2789 CONECT 2788 2787 2793 CONECT 2789 2787 2790 2791 CONECT 2790 2789 CONECT 2791 2789 2792 2793 CONECT 2792 2791 CONECT 2793 2788 2791 2794 CONECT 2794 2793 2795 2803 CONECT 2795 2794 2796 CONECT 2796 2795 2797 CONECT 2797 2796 2798 2803 CONECT 2798 2797 2799 2800 CONECT 2799 2798 CONECT 2800 2798 2801 CONECT 2801 2800 2802 CONECT 2802 2801 2803 CONECT 2803 2794 2797 2802 CONECT 2804 2805 CONECT 2805 2804 2806 2809 CONECT 2806 2805 2807 CONECT 2807 2806 2808 CONECT 2808 2807 2811 CONECT 2809 2805 2810 CONECT 2810 2809 CONECT 2811 2808 2812 CONECT 2812 2811 2813 2814 CONECT 2813 2812 2818 CONECT 2814 2812 2815 2816 CONECT 2815 2814 CONECT 2816 2814 2817 2818 CONECT 2817 2816 CONECT 2818 2813 2816 2819 CONECT 2819 2818 2820 2828 CONECT 2820 2819 2821 CONECT 2821 2820 2822 CONECT 2822 2821 2823 2828 CONECT 2823 2822 2824 2825 CONECT 2824 2823 CONECT 2825 2823 2826 CONECT 2826 2825 2827 CONECT 2827 2826 2828 CONECT 2828 2819 2822 2827 MASTER 419 0 4 10 20 0 9 9 3437 4 74 28 END
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Related entries of code: 2bqz
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
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RCSB PDB
PDBbind
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Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
3lk4
RCSB PDB
PDBbind
29-mer
Entry Information
PDB ID
2bqz
Complex Type
Protein-Protein
PDBbind Subset
general set
Protein Name
histone methyltransferase
Ligand Name
29-mer
EC.Number
E.C.2.1.1.43
Resolution
1.5(Å)
Affinity (Kd/Ki/IC50)
Kd=20uM
Release Year
2005
Protein/NA Sequence
Check fasta file
Primary Reference
Genes Dev.v19;pp.1444
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q9NQR1
P62805
Entrez Gene ID
NCBI Entrez Gene ID:
387893
121504
554313
8294
8359
8360
8361
8362
8363
8364
8365
8366
8367
8368
8370
ASD
Information of known allosteric effects of PDB entries
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