Browse entries in the PDBbind-CN Database

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Related entries of code: 5t5g
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1zkkRCSB PDB    PDBbind167aa, >1ZKK_1|Chains... *
2bqzRCSB PDB    PDBbind161aa, >2BQZ_1|Chains... at 100%
3f9wRCSB PDB    PDBbind166aa, >3F9W_1|Chains... at 96%
3f9yRCSB PDB    PDBbind166aa, >3F9Y_1|Chains... at 96%
5tegRCSB PDB    PDBbind160aa, >5TEG_1|Chains... at 99%
5th7RCSB PDB    PDBbind148aa, >5TH7_1|Chains... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5th7RCSB PDB    PDBbind75P
Entry Information
PDB ID5t5g
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameN-lysine methyltransferase KMT5A
Ligand Name75P
EC.Number E.C.2.1.1.-
Resolution 2.1(Å)
Affinity (Kd/Ki/IC50)Kd=1.3uM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) J. Med. Chem. Vol. 59: pp. 9881-9889
Ligand Properties
Formula C24H40N6O2
Molecular Weight 444.613
Exact Mass 444.321
No. of atoms 72
No. of bonds 75
Polar Surface Area 91.59
LOGP Value 3.40      (Computed with XLOGP3)
2.83      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 12
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q9NQR1  
Entrez Gene IDNCBI Entrez Gene ID: 387893  
ASDInformation of known allosteric effects of PDB entries
 
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