Browse entries in the PDBbind-CN Database

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Related entries of code: 5th7
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1zkkRCSB PDB    PDBbind167aa, >1ZKK_1|Chains... *
2bqzRCSB PDB    PDBbind161aa, >2BQZ_1|Chains... at 100%
3f9wRCSB PDB    PDBbind166aa, >3F9W_1|Chains... at 96%
3f9yRCSB PDB    PDBbind166aa, >3F9Y_1|Chains... at 96%
5t5gRCSB PDB    PDBbind148aa, >5T5G_1|Chain... at 98%
5tegRCSB PDB    PDBbind160aa, >5TEG_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5t5gRCSB PDB    PDBbind75P
Entry Information
PDB ID5th7
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameN-lysine methyltransferase KMT5A
Ligand Name75P
EC.Number E.C.2.1.1.-
Resolution 1.95(Å)
Affinity (Kd/Ki/IC50)IC50=6.9uM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) J. Med. Chem. Vol. 59: pp. 9881-9889
Ligand Properties
Formula C20H29N5O3
Molecular Weight 387.476
Exact Mass 387.227
No. of atoms 57
No. of bonds 59
Polar Surface Area 88.61
LOGP Value 3.44      (Computed with XLOGP3)
3.10      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 10
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q9NQR1  
Entrez Gene IDNCBI Entrez Gene ID: 387893  
ASDInformation of known allosteric effects of PDB entries
 
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