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Related entries of code: 2i0v
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2i0yRCSB PDB    PDBbind335aa, >2I0Y_1|Chain... at 91%
2i1mRCSB PDB    PDBbind333aa, >2I1M_1|Chain... at 90%
3beaRCSB PDB    PDBbind333aa, >3BEA_1|Chain... at 91%
3dpkRCSB PDB    PDBbind335aa, >3DPK_1|Chain... at 91%
3krjRCSB PDB    PDBbind335aa, >3KRJ_1|Chain... at 91%
3krlRCSB PDB    PDBbind335aa, >3KRL_1|Chain... at 91%
3lcdRCSB PDB    PDBbind329aa, >3LCD_1|Chain... at 95%
3lcoRCSB PDB    PDBbind324aa, >3LCO_1|Chain... at 98%
4hw7RCSB PDB    PDBbind343aa, >4HW7_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID2i0v
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamecFMS tyrosine kinase
Ligand Name6C3
EC.Number E.C.2.7.10.1
Resolution 2.8(Å)
Affinity (Kd/Ki/IC50)IC50=160nM
Release Year2006
Protein/NA SequenceCheck fasta file
Primary Reference J. Biol. Chem. 2007, 282, 4094-4101.
Ligand Properties
Formula C19H15ClN2O2
Molecular Weight 338.788
Exact Mass 338.082
No. of atoms 39
No. of bonds 42
Polar Surface Area 55.13
LOGP Value 3.73      (Computed with XLOGP3)
4.64      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P07333  
Entrez Gene IDNCBI Entrez Gene ID: 1436  
ASDInformation of known allosteric effects of PDB entries
 
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