Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 3dpk
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2i0vRCSB PDB    PDBbind335aa, >2I0V_1|Chain... at 91%
2i0yRCSB PDB    PDBbind335aa, >2I0Y_1|Chain... at 91%
2i1mRCSB PDB    PDBbind333aa, >2I1M_1|Chain... at 90%
3beaRCSB PDB    PDBbind333aa, >3BEA_1|Chain... at 91%
3krjRCSB PDB    PDBbind335aa, >3KRJ_1|Chain... at 91%
3krlRCSB PDB    PDBbind335aa, >3KRL_1|Chain... at 91%
3lcdRCSB PDB    PDBbind329aa, >3LCD_1|Chain... at 95%
3lcoRCSB PDB    PDBbind324aa, >3LCO_1|Chain... at 98%
4hw7RCSB PDB    PDBbind343aa, >4HW7_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID3dpk
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMacrophage colony-stimulating factor-1 receptor, kinase domain
Ligand Name8C5
EC.Number E.C.2.7.10.1
Resolution 1.95(Å)
Affinity (Kd/Ki/IC50)IC50=4.1nM
Release Year2009
Protein/NA SequenceCheck fasta file
Primary Reference (2009) J.Med.Chem. Vol. 52: pp. 1081-1099
Ligand Properties
Formula C27H35N6O3
Molecular Weight 491.605
Exact Mass 491.277
No. of atoms 71
No. of bonds 75
Polar Surface Area 102.58
LOGP Value 4.87      (Computed with XLOGP3)
4.59      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11362  P07333  
Entrez Gene IDNCBI Entrez Gene ID: 2260  1436  
ASDInformation of known allosteric effects of PDB entries
 
This site has been visited times since Nov 2007.


Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com