Browse entries in the PDBbind-CN Database

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Related entries of code: 4hw7
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2i0vRCSB PDB    PDBbind335aa, >2I0V_1|Chain... at 91%
2i0yRCSB PDB    PDBbind335aa, >2I0Y_1|Chain... at 91%
2i1mRCSB PDB    PDBbind333aa, >2I1M_1|Chain... at 90%
3beaRCSB PDB    PDBbind333aa, >3BEA_1|Chain... at 91%
3dpkRCSB PDB    PDBbind335aa, >3DPK_1|Chain... at 91%
3krjRCSB PDB    PDBbind335aa, >3KRJ_1|Chain... at 91%
3krlRCSB PDB    PDBbind335aa, >3KRL_1|Chain... at 91%
3lcdRCSB PDB    PDBbind329aa, >3LCD_1|Chain... at 95%
3lcoRCSB PDB    PDBbind324aa, >3LCO_1|Chain... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4hw7
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMacrophage colony-stimulating factor 1 receptor (C667T, C830S, C907T mutation)
Ligand Name64M
EC.Number E.C.2.7.10.1
Resolution 2.9(Å)
Affinity (Kd/Ki/IC50)IC50=0.062uM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) Proc.Natl.Acad.Sci.USA Vol. 110: pp. 5689-5694
Ligand Properties
Formula C22H19F3N4O
Molecular Weight 412.408
Exact Mass 412.151
No. of atoms 49
No. of bonds 52
Polar Surface Area 62.83
LOGP Value 4.83      (Computed with XLOGP3)
5.26      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P07333  
Entrez Gene IDNCBI Entrez Gene ID: 1436  
ASDInformation of known allosteric effects of PDB entries
 
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