Browse entries in the PDBbind-CN Database

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Related entries of code: 5ut0
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4fvqRCSB PDB    PDBbind289aa, >4FVQ_1|Chain... *
4fvrRCSB PDB    PDBbind289aa, >4FVR_1|Chain... at 99%
5uszRCSB PDB    PDBbind289aa, >5USZ_1|Chain... at 100%
5ut4RCSB PDB    PDBbind289aa, >5UT4_1|Chain... at 100%
5ut6RCSB PDB    PDBbind289aa, >5UT6_1|Chain... at 100%
6g3cRCSB PDB    PDBbind272aa, >6G3C_1|Chains... at 99%
5winRCSB PDB    PDBbind277aa, >5WIN_1|Chain... at 100%
5wikRCSB PDB    PDBbind277aa, >5WIK_1|Chain... at 100%
5wijRCSB PDB    PDBbind277aa, >5WIJ_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4qmmRCSB PDB    PDBbind35R
Entry Information
PDB ID5ut0
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameTyrosine-protein kinase JAK2 JH2 domain
Ligand Name35R
EC.Number E.C.-.-.-.-
Resolution 2.1(Å)
Affinity (Kd/Ki/IC50)Kd=1323nM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) ACS Med Chem Lett Vol. 8: pp. 618-621
Ligand Properties
Formula C19H24N7O2
Molecular Weight 382.440
Exact Mass 382.199
No. of atoms 52
No. of bonds 56
Polar Surface Area 112.16
LOGP Value 0.50      (Computed with XLOGP3)
2.69      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 5
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 7
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O60674  
Entrez Gene IDNCBI Entrez Gene ID: 3717  
ASDInformation of known allosteric effects of PDB entries
 
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