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Related entries of code: 5ut6
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4fvqRCSB PDB    PDBbind289aa, >4FVQ_1|Chain... *
4fvrRCSB PDB    PDBbind289aa, >4FVR_1|Chain... at 99%
5uszRCSB PDB    PDBbind289aa, >5USZ_1|Chain... at 100%
5ut0RCSB PDB    PDBbind289aa, >5UT0_1|Chain... at 100%
5ut4RCSB PDB    PDBbind289aa, >5UT4_1|Chain... at 100%
6g3cRCSB PDB    PDBbind272aa, >6G3C_1|Chains... at 99%
5winRCSB PDB    PDBbind277aa, >5WIN_1|Chain... at 100%
5wikRCSB PDB    PDBbind277aa, >5WIK_1|Chain... at 100%
5wijRCSB PDB    PDBbind277aa, >5WIJ_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5ut6
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameTyrosine-protein kinase JAK2
Ligand Name8MY
EC.Number E.C.-.-.-.-
Resolution 1.65(Å)
Affinity (Kd/Ki/IC50)Kd=57.3uM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) ACS Med Chem Lett Vol. 8: pp. 614-617
Ligand Properties
Formula C15H13N7O
Molecular Weight 307.310
Exact Mass 307.118
No. of atoms 36
No. of bonds 38
Polar Surface Area 125.67
LOGP Value 0.90      (Computed with XLOGP3)
2.01      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O60674  
Entrez Gene IDNCBI Entrez Gene ID: 3717  
ASDInformation of known allosteric effects of PDB entries
 
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