Browse entries in the PDBbind-CN Database

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Related entries of code: 6gj7
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1cluRCSB PDB    PDBbind166aa, >1CLU_1|Chain... at 92%
1d8eRCSB PDB    PDBbind11aa, >1D8E_3|Chain... at 100%
1he8RCSB PDB    PDBbind166aa, >1HE8_2|Chain... at 92%
1nvuRCSB PDB    PDBbind166aa, >1NVU_1|Chains... at 92%
1wq1RCSB PDB    PDBbind166aa, >1WQ1_1|Chain... at 92%
4dstRCSB PDB    PDBbind189aa, >4DST_1|Chain... *
4dsuRCSB PDB    PDBbind189aa, >4DSU_1|Chain... at 100%
4epyRCSB PDB    PDBbind170aa, >4EPY_1|Chain... at 98%
4k81RCSB PDB    PDBbind171aa, >4K81_2|Chains... at 90%
4nyiRCSB PDB    PDBbind167aa, >4NYI_1|Chain... at 92%
4nyjRCSB PDB    PDBbind166aa, >4NYJ_2|Chain... at 92%
4nymRCSB PDB    PDBbind166aa, >4NYM_2|Chain... at 92%
5kykRCSB PDB    PDBbind169aa, >5KYK_1|Chains... at 98%
6b0vRCSB PDB    PDBbind170aa, >6B0V_1|Chains... at 97%
6b0yRCSB PDB    PDBbind170aa, >6B0Y_1|Chains... at 97%
6d55RCSB PDB    PDBbind167aa, >6D55_3|Chain... at 92%
6d56RCSB PDB    PDBbind167aa, >6D56_3|Chain... at 92%
6d59RCSB PDB    PDBbind167aa, >6D59_3|Chain... at 92%
6d5eRCSB PDB    PDBbind167aa, >6D5E_3|Chain... at 92%
6d5gRCSB PDB    PDBbind167aa, >6D5G_3|Chain... at 92%
6d5hRCSB PDB    PDBbind167aa, >6D5H_3|Chain... at 92%
6d5jRCSB PDB    PDBbind167aa, >6D5J_3|Chain... at 92%
6fa2RCSB PDB    PDBbind171aa, >6FA2_3|Chain... at 96%
6fa3RCSB PDB    PDBbind172aa, >6FA3_2|Chain... at 96%
6fa4RCSB PDB    PDBbind173aa, >6FA4_2|Chains... at 96%
6quwRCSB PDB    PDBbind170aa, >6QUW_1|Chains... at 99%
6quvRCSB PDB    PDBbind170aa, >6QUV_1|Chains... at 99%
6pgpRCSB PDB    PDBbind183aa, >6PGP_1|Chains... at 90%
6pgoRCSB PDB    PDBbind183aa, >6PGO_1|Chains... at 90%
6p8zRCSB PDB    PDBbind183aa, >6P8Z_1|Chains... at 90%
6p8yRCSB PDB    PDBbind183aa, >6P8Y_1|Chains... at 90%
6p8xRCSB PDB    PDBbind183aa, >6P8X_1|Chains... at 90%
6gj8RCSB PDB    PDBbind169aa, >6GJ8_1|Chain... at 99%
6gj6RCSB PDB    PDBbind170aa, >6GJ6_1|Chain... at 99%
6gj5RCSB PDB    PDBbind170aa, >6GJ5_1|Chains... at 98%
6d5wRCSB PDB    PDBbind167aa, >6D5W_2|Chain... at 92%
6ccxRCSB PDB    PDBbind187aa, >6CCX_2|Chain... at 97%
6oimRCSB PDB    PDBbind183aa, >6OIM_1|Chain... at 90%
6cc9RCSB PDB    PDBbind187aa, >6CC9_2|Chain... at 97%
6v5lRCSB PDB    PDBbind169aa, >6V5L_1|Chain... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6gj7
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameKRAS G12D
Ligand NameF0B
EC.Number E.C.-.-.-.-
Resolution 1.67(Å)
Affinity (Kd/Ki/IC50)IC50=0.87uM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Proc.Natl.Acad.Sci.USA Vol. 116: pp. 15823-15829
Ligand Properties
Formula C33H29N4O2
Molecular Weight 513.609
Exact Mass 513.229
No. of atoms 68
No. of bonds 74
Polar Surface Area 86.66
LOGP Value 4.81      (Computed with XLOGP3)
5.30      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 7
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P01116  
Entrez Gene IDNCBI Entrez Gene ID: 3845  
ASDInformation of known allosteric effects of PDB entries
 
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