Browse entries in the PDBbind-CN Database

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Related entries of code: 2xwe
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2nsxRCSB PDB    PDBbind497aa, >2NSX_1|Chains... at 100%
2v3dRCSB PDB    PDBbind505aa, >2V3D_1|Chains... *
2v3eRCSB PDB    PDBbind505aa, >2V3E_1|Chains... at 100%
2wcgRCSB PDB    PDBbind505aa, >2WCG_1|Chains... at 100%
2xwdRCSB PDB    PDBbind505aa, >2XWD_1|Chains... at 100%
3rikRCSB PDB    PDBbind497aa, >3RIK_1|Chains... at 100%
3rilRCSB PDB    PDBbind497aa, >3RIL_1|Chains... at 100%
5lvxRCSB PDB    PDBbind497aa, >5LVX_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
2wc4RCSB PDB    PDBbindAMF
Entry Information
PDB ID2xwe
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameGLUCOSYLCERAMIDASE
Ligand NameAMF
EC.Number E.C.3.2.1.45
Resolution 2.31(Å)
Affinity (Kd/Ki/IC50)Ki=0.95uM
Release Year2011
Protein/NA SequenceCheck fasta file
Primary Reference (2011) Org.Biomol.Chem. Vol. 9: pp. 4160
Ligand Properties
Formula C15H28N2O4S
Molecular Weight 332.459
Exact Mass 332.177
No. of atoms 50
No. of bonds 51
Polar Surface Area 121.82
LOGP Value 1.44      (Computed with XLOGP3)
0.47      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 11
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P04062  
Entrez Gene IDNCBI Entrez Gene ID: 2629  
ASDInformation of known allosteric effects of PDB entries
 
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