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Related entries of code: 5y0z
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5dy5RCSB PDB    PDBbind304aa, >5DY5:A|PDBID|CHAIN|... at 99%
5marRCSB PDB    PDBbind303aa, >5MAR:B|PDBID|CHAIN|... at 99%
5matRCSB PDB    PDBbind303aa, >5MAT:C|PDBID|CHAIN|... at 99%
5y5nRCSB PDB    PDBbind336aa, >5Y5N:A|PDBID|CHAIN|... at 96%
5yqlRCSB PDB    PDBbind306aa, >5YQL:A|PDBID|CHAIN|... at 98%
5yqnRCSB PDB    PDBbind306aa, >5YQN:A|PDBID|CHAIN|... at 98%
5yqoRCSB PDB    PDBbind306aa, >5YQO:A|PDBID|CHAIN|... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5y0z
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameSIRT2
Ligand Name8K9
EC.Number E.C.-.-.-.-
Resolution 2(Å)
Affinity (Kd/Ki/IC50)IC50=0.46uM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) Philos. Trans. R. Soc. Lond., B, Biol. Sci. Vol. 373: pp. -
Ligand Properties
Formula C30H45N2O3
Molecular Weight 481.690
Exact Mass 481.343
No. of atoms 80
No. of bonds 83
Polar Surface Area 55.9
LOGP Value 6.13      (Computed with XLOGP3)
5.23      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 10
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q8IXJ6  
Entrez Gene IDNCBI Entrez Gene ID: 22933  
ASDInformation of known allosteric effects of PDB entries

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