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Related entries of code: 5y5n
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5dy5RCSB PDB    PDBbind304aa, >5DY5:A|PDBID|CHAIN|... at 99%
5marRCSB PDB    PDBbind303aa, >5MAR:B|PDBID|CHAIN|... at 99%
5matRCSB PDB    PDBbind303aa, >5MAT:C|PDBID|CHAIN|... at 99%
5y0zRCSB PDB    PDBbind293aa, >5Y0Z:B|PDBID|CHAIN|... at 100%
5yqlRCSB PDB    PDBbind306aa, >5YQL:A|PDBID|CHAIN|... at 98%
5yqnRCSB PDB    PDBbind306aa, >5YQN:A|PDBID|CHAIN|... at 98%
5yqoRCSB PDB    PDBbind306aa, >5YQO:A|PDBID|CHAIN|... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5y5n
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namesirtuin-2
Ligand Name8NO
EC.Number E.C.-.-.-.-
Resolution 2.3(Å)
Affinity (Kd/Ki/IC50)IC50=1.74uM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) CHEM SCI Vol. 8: pp. 6400-6408
Ligand Properties
Formula C21H20N2O2
Molecular Weight 332.396
Exact Mass 332.152
No. of atoms 45
No. of bonds 47
Polar Surface Area 64.35
LOGP Value 4.82      (Computed with XLOGP3)
4.92      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 1
No. of Rotatable Bonds: 7
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q8IXJ6  
Entrez Gene IDNCBI Entrez Gene ID: 22933  
ASDInformation of known allosteric effects of PDB entries

 
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