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Related entries of code: 5yqo
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5dy5RCSB PDB    PDBbind304aa, >5DY5:A|PDBID|CHAIN|... at 99%
5marRCSB PDB    PDBbind303aa, >5MAR:B|PDBID|CHAIN|... at 99%
5matRCSB PDB    PDBbind303aa, >5MAT:C|PDBID|CHAIN|... at 99%
5y0zRCSB PDB    PDBbind293aa, >5Y0Z:B|PDBID|CHAIN|... at 100%
5y5nRCSB PDB    PDBbind336aa, >5Y5N:A|PDBID|CHAIN|... at 96%
5yqlRCSB PDB    PDBbind306aa, >5YQL:A|PDBID|CHAIN|... at 98%
5yqnRCSB PDB    PDBbind306aa, >5YQN:A|PDBID|CHAIN|... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5yqo
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namesirtuin 2
Ligand NameL5C
EC.Number E.C.-.-.-.-
Resolution 1.48(Å)
Affinity (Kd/Ki/IC50)IC50=0.815uM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) Eur J Med Chem Vol. 155: pp. 806-823
Ligand Properties
Formula C26H26N6O3S
Molecular Weight 502.588
Exact Mass 502.179
No. of atoms 62
No. of bonds 65
Polar Surface Area 136.33
LOGP Value 3.36      (Computed with XLOGP3)
4.54      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 11
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q8IXJ6  
Entrez Gene IDNCBI Entrez Gene ID: 22933  
ASDInformation of known allosteric effects of PDB entries

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